Group Title: Animal Science Department mimeograph report - Florida Agricultural Experiment Station ; no. AN64-2
Title: Comparison of bacitracin, zinc bacitracin and a combination of oxytetracycline and oleandomycin for swine
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 Material Information
Title: Comparison of bacitracin, zinc bacitracin and a combination of oxytetracycline and oleandomycin for swine
Series Title: Animal Science Department mimeograph report
Physical Description: 3 p. : ; 28 cm.
Language: English
Creator: Combs, G. E ( George Ernest ), 1927-
Wallace, H. D ( Harold Dean )
University of Florida -- Agricultural Experiment Station
Publisher: Florida Agricultural Experiment Station
Place of Publication: Gainesville Fla
Publication Date: 1963
Subject: Swine -- Feeding and feeds -- Florida   ( lcsh )
Antibiotics in animal nutrition -- Florida   ( lcsh )
Swine -- Growth -- Florida   ( lcsh )
Genre: government publication (state, provincial, terriorial, dependent)   ( marcgt )
non-fiction   ( marcgt )
Statement of Responsibility: G.E. Combs and H.D. Wallace.
General Note: Caption title.
General Note: "July, 1963."
 Record Information
Bibliographic ID: UF00072947
Volume ID: VID00001
Source Institution: University of Florida
Rights Management: All rights reserved by the source institution and holding location.
Resource Identifier: oclc - 77528829

Full Text

Animal Science Department Florida Agricultural
Mimeograph Report AN64-2 Experiment Station
Gainesville, Florida
July, 1963


G. E. Combs and H. D. Wallace I/

Among the benefits derived from adding antibiotics to swine rations
are increased rate and efficiency of gain, control of non-specific scours
and a lowering of the overall disease level in swine facilities where
they are used continuously. It has also been reported that certain anti-
biotics or combination of antibiotics.are more effective in one or more
of these aspects than others; also, that in instances where a particular
antibiotic has been used extensively over a period of years some benefit
may be derived from using another antibiotic or antibiotic combination
(Fla. Ani. Sci. Mimeo. Series 63-5 and 63-8).

The following study was initiated to compare the effectiveness of
bacitracin, zinc bacitracin and oxytetracycline and oleandomycin com-
bination!iraomyxin) in controlling non-specific scours and in improving
rate and efficiency of gain.


One hundred pigs weaned at 2 weeks of age were allotted on the
basis of weight and litter to four treatment groups of 25 pigs each.
All groups were self-fed ag libitum in concrete floor pens. Water was
provided in automatic waterers and the experiment was terminated when
all groups reached market weight.

The composition of the basal rations is presented in table 1.
Basal ration I was fed until the groups averaged approximately 50
pounds; basal ration 2 was then fed until the experiment was termi-

I/ Combs and Wallace, Associate Animal Nutritionist and Animal
Nutritionist respectively, Department of Animal Science.

The assistance of W. E. Collins and L. S. Taylor, Swine Herds-
men, is acknowledged.

Bacitracin was supplied by Pabst Brewing Co., Zinc bacitracin
supplied by Commercial Solvents Corp. and Taomyxin by Chas.
Pfizer and Co.

The experimental treatments were as follows:

Antibiotic (qrain/ton)

2 wks. 7 wks. 51 Ibs.
until until until
6 wks. 50 Ibs. market
of age weight

Treatment I (control) 0 0 0
Treatment 2 (bacitracin) 100 50 10
Treatment 3 (zinc bacitracin) 100 50 10
Treatment 4 oxytetracyclinee 100 50 10
oleandomycin combi-

Results and Discussion

The data pertaining to the daily gain and feed efficiency of the
treatment groups are summarized in table 2. Although the magnitude of
the difference between the daily gain of the control and the antibiotic
supplemented groups was relatively small the difference was statistically
significant. There were, however, no statistically significant differences
among the groups that received either bacitracin, zinc bacitracin or the
oxytetracycline oleandomycin combination. The feed required per pound
of gain was similar for all treatments.

No particular scouring problem was evident during the experiment
which precludes an evaluation concerning the comparative effectiveness
of the antibiotics in controlling this problem.


Pigs weaned at 2 weeks of age were fed rations containing bacitracin,
or a combination of oxytetracycline and oleandomycin until market weight.

The average daily gains of pigs fed the antibiotic supplemented
rations were significantly faster than those which did not receive an
antibiotic. The gains of all antibiotic supplemented groups were statis-
tically similar. The feed required per pound of gain was similar for all
treatment groups.

The incidence of scours was low for all groups; therefore, the com-
parative efficacy of the antibiotics in controlling this condition could
not be evaluated.


Table I. Composition of Basal Rations

To 50 Ibs.

51 to 200 lbs.
I ; wea; h+

Ground yellow corn
Soybean meal
Trace minerals I/
Vitamin supplement 2/
Vitamin B12 supplement 3/
Vitamin A and D premix 4/




1/ Contributed 84 ppm. zinc when used at .10 level.




Z/ Contained the following per pound: riboflavin, 2000 mg.; panto-
thenic'acid, 4000 mg,; niacin, 900Q mg.; choline chloride, 10,000 mg.

5/ Contained 12 mg. vitamin B12 per pound.

'/ Contained vitamin A (10,000 I.U./gm.), 14 gm; vitamin D (9000
I.U./gm.), 4 gm. and corn, 890 gm.

Table 2. Performance of Pigs Fed Antibiotics From
2 Weeks of Age until Market Weight.

Treatment Basal Babitracin Zinc Bacitracin Taomyxin

No. pigs 25 25 25 25
Av. init. weight, Ib. 8.1 8.1 8,1 8.1
Av. final weight, lb. 180.2 189.3 191.6 194.2
Av. daily gain, lb. 1.23a 1.29 1.31 1.33
Av. daily feed, lb. 3.60 3.86 3.79 3.98
Feed/lb. gain, Ib. 2.92 2.99 2.89 2.99

a/ Significantly less than bacitracin (P<.05) and zinc bacitracin
and oxytetracycline-oloandomypin (P<-.01).

1000 copies

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