Morbidity and mortality

COMMU ICABLE DISEASE CENTER


15, No. 15







Ending
I 16, 1966


acd


U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE


CURRENT TRENDS
POST-INFECTIOUS ENCEPHALITIS

During the first quarter of 1966, 209 cases of post-
infectious encephalitis of specified etiology were notified
from 18 States (Table 1). For the comparable period in
1965 there were 187 reported cases of post-infectious
encephalitis. Mumps was the most frequently reported
cause of encephalitis in both years, accounting for more
than one-half the total. In the first 13 weeks of 1966, one
case of encephalitis in association with cat scratch
fever occurred in Tennessee.
Measles encephalitis was reported twice as frequently
during the first quarter of 1966 as during the comparable
period in 1965. In some States (Illinois and Kentucky in


('OA A'E TS
Current Trend.I
Post-Infectious n hal iti. .................. 125
Pneumonia-lnfl un-n /.I a I th tin In122 I. h. ( t I s 127
Invcstigation.a i \' ilti Pro!r .m .... . 1



Table 2), the increase in measles encephalitis reporting
was parallel to an increase in the reporting of total
measles cases. In Michigan, however, the total reported
measles encephalitis cases increased even though the
total measles incidence reported decreased. Forthe United
States in the first quarter of 1965, the ratio of reported
measles encephalitis to reported measles cases was 0.27
(Continued on page 126)


CASES OF SPECIFIED NOTIFIABLE DISEASES: UNITED STATES
(Cumulative totals include revised and delayed reports through previous weeks)
15th WEEK ENDED CUMULATIVE, FIRST 15 WEEKS
MEDIAN
DISEASE APRIL 16, APRIL 17, 1961-1965 MEDIAN
1966 1965 1966 1965 1961-1965
Aseptic meningitis ... ................. 31 22 27 420 437 361
Brucellosis. .. .......... .. 3 2 6 53 56 101
Diphtheria ........... -.... ... 5 8 40 67 99
Encephalitis, primary:
Arthropod-borne & unspecified ......... 32 31 359 448
Encephalitis, post-infectious ...... 17 15 246 219 -
Hepatitis, serum ..34 674 792 369 11710 15
Hepatitis, infectious. ................... 599 10,422 15489
Measles rubeolaa) ..... ........ 7,575 10,859 17.542 109.279 139,594 183,291
Poliomyelitis, Total (including unspecified) 1 2 7 6 43
Paralytic .. .. .. ..... 1 1 6 4 38
Nonparalytic ............... ... 2
Meningococcal infections. Total ........ 111 103 54 1.534 1,315 898
Civilian ... 104 82 1,336 1,197 -
Mil i r ... .. 7 21 198 118
Rubella (German measles) ...... 1,885 20.820 -
Streptococcal sore throat & Scarlet fever 10,763 9,949 8.966 175,641 167,786 146,975
Tetanus ............ .... 3 2 28 53 -
Tularemia .... 2 47 57
Typhoid fever .... ...... ....... 4 4 9 76 98 106
Typhus, tick-borne (Rky. Mt Spotted fever) 9 6

Rabies in Animals.. ..................... 106 109 109 1.289 1,541 1,221

NOTIFIABLE DISEASES OF LOW FREQUENCY
Cum. Cum.
Anthrax: .. ..... . 2 Botulism: .... .. ..... 1
Leptospirosis: . ....... 9 Trichinosis: Ohio-,1 Iowa-1 .......... 33
Malaria: N.C.-1, Calif.-2, P.R.-I .. ........ 84 Rabies in Man: ...... .. ...... .......
Psittacosis: Wisc.-1, Texas-1 . 16 Rubella. Congenital Syndrome: 10
Typhus, murine: .. .. ..... ....... ... 6 ........








Morbidity and Mortality Weekly Report


CURRENT TRENDS
POST-INFECTIOUS ENCEPHALITIS
(Continued from front page)



Table 1
Reported Cases of Post-Infectious and Post-Immunization Encephalitis
First Quarter Ending April 2, 1966 (Weeks 1-13)


State


Arkansas . ...........
California ...................
Connecticut ... ..........
Florida . ... ........
Illinois . ....... .
Iowa ...... ...............
Kentucky . . .
Louisiana . ...........
M aryland . ...........
Massachusetts .. .. ........
M ichigan . .......... .
Minnesota ....... ............
New York, Upstate . .....
Pennsylvania . .........
Rhode Island ......... .......
Tennessee ....... ..........
Texas .. ...
Washington . ..........


Mumps


-I- -1


Measles


13


17
1
6
2

1
6
4
1
5

2
3
1


Chickenpox


6

1
1


1
1


2
6
3
1

2
2


First Quarter Total
1966 ............ .... 107 62 28
1965 ................... 114 31 33


Other Specified


Herpes Simplex-1
Influenza-1

Herpes Simplex-2
Influenza-2
Influenza-1


Herpes Zoster-1




Herpes Zoster-1, Vaccinia-1

Cat Scratch Fever-1
Influenza-1


(States not reporting a case not, listed.)


per thousand cases of measles, and in the first quarter of
1966 this ratio was 0.66 per thousand. Some additional
information is available about 10 cases of post-measles
encephalitis in Illinois and 5 cases in Michigan. Thirteen
of the 15 patients were between the ages of 3 years and
8 years, one patient was 16 years old, and one patient


who died was 21 months old. There were 11 males and
4 females. The symptoms ranged from headache and stiff
neck to coma, convulsions, and signs of corticospinal
tract involvement.
(Reported by the CNS Disease Unit, Epidemiology Branch,
CDC.)


Table 2
Reported Measles Encephalitis in Four States
First 13 Weeks, 1965 and 1966


Measles
Encephalitis
Cases

12
1

2


1965


Measles
Cases


5,115
651
778
11,187


Rate 1000
Measles
Cases

2.3
1.5
0.0
0.2


Measles
Encephalitis
Cases


126


APRIL 16, 1966


State


California .
Illinois .
Kentucky
Michigan


Rate/1000
Measles
Cases


1966


Measles
Cases


.-1.' "7
7,650
3,391
5. I, 14









APRIL t16, 1966


Morbidity and Mortality Weekly Report





Figure 1
PNEUMONIA-INFLUENZA DEATHS IN 122 UNITED STATES CITIES


WN
CENTRAL 200-
0 10 CITIES
150-
75-

50- -f100'
25- o-


WK NO 40 44 48 52 4 8 12 16 20 24 28 32
1965 1966
150-
loo- MOUNTAIN
8 CITIES 125



75
50
50
25


40 44 48 52 4 8 12 16 20 24 28 32 40 48 5 4 8 12 16 20 24 28 236
1965 | 1966 .965 1966


E.S
CENTRAL
8 CITIES


200

150



50


MIDDLE
ATLANTIC
20 CITIES


40 44 48 52 4 2 16 20 24 28 32 40 44 48 5 4 8 2 6 20 24 28 32 40 44 48 52 4 8 2 16 20 24 20 52 36
196531966 196511966 96511966

PACIFIC W.S. SOUTH
16 CITIES CENTRAL ATLANTIC


13 CITIES


150


00


~A~~]-L~So


12 CITIES


...i...i...;..~.. .L, i L,,,I,,, 1,, I .. ,h H,,rh... H I ..,i,,.,,..I,,,,h l ,hlh ,l d,, I lllt ,,
SC '* -2 40 44 48 52 4 2 16 20 24 28 32 40 44 2 4 8 4i 26 20 24 28 32 36
1965 1966 1965 | 1966 965 i 3966


Excess mortality due to influenza and pneumonia as
measured in 122 U.S. cities has risen slightly over that
of the previous week, remaining above the epidemic
threshold for the seventh consecutive week. This slight
rise in excess mortality for the 122 cities is no longer
predominantly related to the excess mortality recorded
during the A2 riflueinz- epidemics which have occurred
in the Pacific Hegion The rise is being maintained by


the mortality continuing to occur in the Mountain Region
and to that shown in the Middle and South Atlantic Regions
for the second consecutive week. To date only influenza
type B virus has been reported from these latter two
geographic regions.


(Reported by the Influenza-Respiratory Disease Unit,
Epidemiology Branch, CDC.)











128 Morbidity and Mortality Weekly Report



CASES OF SPECIFIED NOTIFIABLE DISEASES: UNITED STATES

FOR WEEKS ENDED

APRIL 16, 1966 AND APRIL 17, 1965 (15th WEEK)



ENCEPHALITIS HEPATITIS
ASEPTIC Primary Post- Both
AREA MENINGITIS BRUCELLOSIS including Infectious DIPHTHERIA Serum Infectious Types
unsp. cases
1966 1965 1966 1966 1965 1966 1966 1965 1966 1966 1965
UNITED STATES... 31 22 3 32 31 17 5 34 599 674

NEW ENGLAND.......... 2 1 2 2 18 45
Maine ............. --- --- --- --- ---- --- --- 12
New Hampshir e...... 1 4
Vermon ............ 1
Massachusetts. .... 2 -- 12 16
Rhode Island....... 2 1 1 7
Connecticut........ 1 4 5

MIDD.E ATLANTIC..... 4 4 2 17 12 91 90
New York City...... 1 1 10 11 12 17
New York, Up-State. 1 1 -- 24 18
New Jersey ....... 1 2 1 15 32
Pennsylvania....... 2 2 1 5 40 23

EAST NORTH CENTRAL... 4 2 8 2 2 1 147 129
Ohio............... 1 3 1 44 22
Indiana............ 4 10 4
Illinois........... 1 1 1 1 16 32
Michigan........... .. 3 1 1 73 61
Wisconsin.......... 4 10

WEST NORTH CENTRAL... 1 I 3 16 51
Minnesota.......... 1 3 2 2
Iowa .............. 5 17
Missouri........... 6 14
North Dakota....... 2
South Dakota.......- --
Nebraska........... -- 1 4
Kansas ............. 12

SOUTH ATLANTI ....... 1 1 2 13 1 3 71 74
Del.ware ........... 1 1
Maryland........... 4 1 21 7
Dist. of Columibia.. 1-
Virginia............ 1 2 1 16 37
West Virginia...... 2 4
North Carolina .... 1 5 4 8
South Carolina ..... 3
Georgia ............ 15 3
Florida ............ .. 1 2 2 12 10

EAST SOUTH CENTRAL... 9 2 3 2 50 46
Kentucky............ 2 2 18 10
Tennessee.......... 2 1 23 7
Alabama............ 2 2 7 12
Mississippi........ 3 2 2 17

WEST SOUTH CENTRAL... 3 3 1 1 -2 4 56 47
Arkansas ........... 2 1 10 1
Louisiana........... 1 8 5
Oklahoma........... -- 1
Texas.............. 3 3 1 3 37 41

MOUNTAIN ............. 2 4 1 2 38 54
Montana ............... 2 3
Idaho................. -3 4
Wyoming ........... -
Colorado............. 1 1 1 -21 17
New Mxico......... 1 5 8
Arizona............ 1 3 5 12
Utah............... 1 1 10
Nevada ............

PACIFIC .............. 5 6 3 6 10 15 112 138
Washington......... I 13 5
Oregon ............. 10 12
California......... 4 6 3 6 10 15 86 113
Alaska............ 1 8
Hawaii ............. 1 -- 2

Puerto Rico........... 1 21 42










129


Morbidity and Mortality Weekly Report


CASESS OF SPECIFIED NOTIFIABLE DISEASES: I NITII1) STATES

FOR WEEKS ENDED

APRIL 16, 1966 AND APRIL 17, 1965 (15th WEEK) CONTINUED


MEASLES (Rubeola)
AREA --- --- -
Cumulative
1966 1966 1965

UNITED STATES... 7,575 109,279 139,594

NEW ENGLAND.......... 73 1,318 27,199
Maine................ --- 146 2,010
New Hampshire...... 20 335
Vermont............. 4 202 426
Massachusetts...... 35 507 15,165
Rhode Island ....... 57 2,990
Connecticut........ 33 386 6,273

MIDDLE ATLANTIC..... 653 13,135 5,554
New York City...... 332 6,720 557
New York, Up-State. 72 1,355 1,826
New Jersey......... 45 1,396 966
Pennsylvania....... 204 3,664 2,205

EAST NORTH CENTRAL... 2,450 41,537 26,268
Ohio ............... 291 3,266 5,597
Indiana............. 114 2,494 1,041
Illinois........... 496 8,571 1,046
Michigan ........... 534 6,897 13,828
Wisconsin.......... 1,015 20,309 4,746

WEST NORTH CENTRAL.. 371 5,115 10,851
Minnesota.......... 5 1,238 354
Iowa ............... 342 2,782 6,002
Missouri........... 1 315 1,599
North Dakota...... 23 735 2,559
South Dakota....... 3 58
Nebraska........... 42 279
Kansas............. NN NN NN

SOUTH ATLANTIC....... 610 8,454 16,337
Delaware............ 13 117 345
Maryland............ 58 1,309 584
Dist. of Columbia.. 7 302 22
Virginia........... 95 846 2,562
West Virginia...... 187 3,293 9,882
North Carolina..... 7 145 194
South Carolina..... 15 399 629
Georgia............ 10 177 461
Florida............ 218 1,866 1,658

EAST SOUTH CENTRAL... 769 12,034 8,121
Kentucky............. 132 3,690 976
Tennessee........... 505 6,955 4,867
Alabama............ 12 778 1,583
Mississippi........ 120 611 695

WEST SOUTH CENTRAL... 1,330 12,541 19,547
Arkansas........... 375 827
Louisiana........... 5 64 47
Oklahoma............ 37 268 120
Texas............... 1,288 11,834 18,553

MOUNTAIN ............. 472 5,913 11,024
Montana............. 49 867 2,705
Idaho.............. 27 614 1,657
Wyoming ............ 82 566
Colorado............ 41 641 2,308
New Mexico.......... 30 332 358
Arizona............ 307 3,174 443
Utah............... 18 179 2,901
Nevada................. 24 86

PACIFIC.............. 847 9,232 14,693
Washington.......... 81 1,791 4,350
Oregon.............. 60 721 2,108
California......... 703 6,614 6,518
Alaska.............. 1 51 102
Haui. ....... 8 1 ,
Puerto Rico........... 128 1,396 986


MENINGOCOCCAL INFECT
TOTAL

Cumulati
1966 966

111 1,534

1 72
7
7
3
29
5
1 21

18 167
1 24
11 47
1 47
5 49

15 224
4 62
6 36
2 42
2 62
1 22

6 80
2 21
12
4 33
3
2
3
6

11 244
3
23
6
2 33
8
2 48
1 34
2 41
4 48

13 129
4 57
5 40
2 23
2 9

11 232
12
2 90
9
9 121

14 56
3
1
1
10 32
3 9
1 8

2

22 330
2 19
2 15
18 280
S 13


2


TIONS,


ve
1965

1,315

66
8
4
1
23
11
19

173
26
40
60
47

159
47
22
39
28
23

68
14
2
35
3
2
5
7

264


4
3I


29
18
42
41
35
66

93
41
26
20
6

216
12
121
16
67

48
1
7

10
7
14
5
2

228
16
18
187
4


3*


Tot,


1966


POLIOMYELITIS
RUBELLA

Cumulative
1965 1966 1966 1966

1 6 1,885

211
211


3
81
21
102

136
26
96

14

708
S 147
155
96
146
164

1 1 1 81

73
S1



I


1 125

12

21
16
16

11

65

- 137
21
109
S7


-3 12

-1

-2 12

178
-- 6
- 2

40

S130



1 297
S 1 140
31
119
4
-- 3

-- 1










130 Morbidity and Mortality Weekly Report


CASES OF SPECIFIED NOTIFIABLE DISEASES: UNITED STATES

FOR WEEKS ENDED

APRIL 16, 1966 AND APRIL 17, 1965 (15th WEEK) CONTINUED


STREPTOCOCCAL TYPHUS FEVER RABIES IN
SORE THROAT & TETANUS TULAREMIA TYPHOID TICK-BORNE ANIMALS
AREA SCARLET FEVER (Rky. Mt. Spotted)
1966 1966 Cum. 1966 Cum. 1966 Cum. 1966 Cum. 1966 Cum.
1966 1966 1966 1966 1966
UNITED STATES... 10,763 3 28 47 4 76 9 106 1,289

NEW ENGLAND .......... 1,630 2 1 3 1 13
Maine................ ... ......-- ... ..
New Hampshire...... 40 1 6
Vermont............ 40 7
Massachusetts....... 385 2 1
Rhode Island....... 56 -
Connecticut........ 1,109 3 -

MIDDLE ATLANTIC ..... 597 1 5 17 1 7 93
New York City...... 28 3 8 -
New York, Up-State. 486 3 7 88
New Jersey........ NN 3 -
Pennsylvania....... 83 1 2 3 1 5

EAST NORTH CENTRAL... 1,505 2 2 12 1 13 21 185
Ohio................ 197 3 6 9 104
Indiana............. 131 1 1 3 2 9 38
Illinois........... 288 5 1 13
Michigan........... 500 1 1 1 2 3 15
Wisconsin.......... 389 1 2 15

WEST NORTH CENTRAL... 349 1 3 1 8 1 15 280
Minnesota.......... 11 3 51
Iowa............... 180 -- 1 3 2 68
Missouri........... 1 1 4 4 106
North Dakota....... 84 1 5
South Dakota....... 16 2 28
Nebraska ........... 2 1 7
Kansas............. 56 2 1 1 2 15

SOUTH ATLANTIC....... 1,143 8 6 1 15 6 12 167
Delaware ........... 117 -
Maryland............ 94 1 5
Dist. of Columbia.. 7 -
Virginia........... 407 2 6 2 11 116
West Virginia...... 327 1 1 18
North Carolina..... 15 2 2 3 -
South Carolina..... 22 1 -
Georgia............ 5 3 1 1 20
Florida............. 149 4 1 13

EAST SOUTH CENTRAL... 1,740 1 12 1 7 14 185
Kentucky............ 230 2 1 1 26
Tennessee........... 1,374 6 4 13 155
Alabama............ 1 4 1 2 4
Mississippi......... 136 -

WEST SOUTH CENTRAL... 1,209 6 11 3 1 29 279
Arkansas........... 2 9 1 2 38
Louisiana.......... 1 3 1 16
Oklahoma........... 66 1 18 68
Texas............... 1,140 3 1 1 9 157

MOUNTAIN.............. 1,502 1 6 3 18
Montana............. 48 2
Idaho .............. 71 -
Wyoming ..........
Colorado........... 929 2 I
New Mexico......... 220 2 5
Arizona............. 104 I 1 10
Utah............... 130 1 3 -
Nevada... ......... -

PACIFIC.................. 1,088 3 1 4 4 69
Washington........ 429 -
Oregon ............. 45 1 -
California......... 513 3 1 3 4 69
Alaska............. 31 -
Hawaii. ... ......7...-
Puerto Rico.......... 6 1 11 3 1 3









Morbidity and limrlalit Weekl Report


DEATHS IN 122 UNITED STATES CITIES FOR WEEK ENDED APRIL 16, 1966

(By place of occurrence and week of filing certificate. Excludes fetal deaths)


All Causes Pneumonia Under All Causes Pneumonia Under
Area All 65 years and 1 year Area All 65 years and I yar
Ages and over Influenza All Ages and over Ifluena
All Ages Causes All Ages Causes


NEW ENGLAND:
Boston, Mass.---------
Bridgeport, Conn.-----
Cambridge, Mass.------
Fall River, Mass.-----
Hartford, Conn.-------
Lowell, Mass.---------
Lynn, Mass.-----------
New Bedford, Mass.----
New Haven, Conn.------
Providence, R. I.-----
Somerville, Mass.-----
Springfield, Mass.----
Waterbury, Conn.------
Worcester, Mass.------

MIDDLE ATLANTIC:
Albany, N. Y.---------
Allentown, Pa.--------
Buffalo, N. Y.--------
Camden, N. J.---------
Elizabeth, N. J.------
Erie, Pa.-------------
Jersey City, N. J.----
Newark, N. J.---------
New York City, N. Y.--
Paterson, N. J.-------
Philadelphia, Pa.-----
Pittsburgh, Pa.-------
Reading, Pa.----------
Rochester, N. Y.------
Schenectady, N. Y.----
Scranton, Pa.---------
Syracuse, N. Y.-------
Trenton, N. J.--------
Utica, N. Y.----------
Yonkers, N. Y.--------

EAST NORTH CENTRAL:
Akron, Ohio-----------
Canton, Ohio----------
Chicago, Ill.---------
Cincinnati, Ohio------
Cleveland, Ohio-------
Columbus, Ohio--------
Dayton, Ohio----------
Detroit, Mich.--------
Evansville, Ind.------
Flint, Mich.----------
Fort Wayne, Ind.------
Gary, Ind.------------
Grand Rapids, Mich.---
Indianapolis, Ind.----
Madison, Wis.---------
Milwaukee, Wis.-------
Peoria, Ill.----------
Rockford, Ill.--------
South Bend, Ind.------
Toledo, Ohio----------
Youngstown, Ohio------

WEST NORTH CENTRAL:
Des Moines, Iowa------
Duluth, Minn.---------
Kansas City, Kans.----
Kansas City, Mo.------
Lincoln, Nebr.--------
Minneapolis, Minn.----
Omaha, Nebr.-----------
St. Louis, Mo.--------
St. Paul, Minn.-------
Wichita, Kans.--------


700 426 36 37
228 126 6 11
34 22 5 2
26 18 1
22 11 3 -
66 35 3 6
18 12 4 -
27 18 3 1
33 23 1 1
52 33 5
54 31 2 4
12 8 1 -
40 29 5 1
34 19 2
54 41 3 3

3,666 2,241 191 137
65 38 2
45 30 1 -
175 99 7 5
42 25 4
44 23 4 1
55 37 3 -
90 63 11 4
123 57 6 9
1,850 1,140 96 69
49 32 5 3
520 316 15 21
205 115 3 5
55 44 7 2
102 75 11 2
22 10 -
40 20 11 3
60 35 1 2
55 31 2 3
26 21 5 -
43 30 3 2

3,052 1,728 139 179
77 42 1 4
29 15 4 4
988 540 40 55
187 99 2 14
249 139 3 14
135 89 4 4
109 67 17 3
395 203 28 32
48 33 2 2
56 26 3 4
54 33 3 2
50 23 4 2
35 22 4 1
167 107 7 5
28 17 -
155 93 7 11
26 15 2
33 20 3 2
56 32 9
105 59 5 5
70 54 2 4

893 561 33 34
58 45 5 1
29 20 2
57 29 1 2
128 71 8 9
25 18 1 -
169 100 7 7
75 43 1 3
222 144 6 5
91 64 1 4
39 27 3 1


percent of divisional total.


SOUTH ATLANTIC:
Atlanta, Ga.------------
Baltimore, Md.----------
Charlotte, N. C.-------
Jacksonville, Fla.-----
Miami, Fla.------------
Norfolk, Va.-----------
Richmond, Va.-----------
Savannah, Ga.----------
St. Petersburg, Fla.---
Tampa, Fla.------------
Washington, D. C.-------
Wilmington, Del.-------

EAST SOUTH CENTRAL:
Birmingham, Ala.-------
Chattanooga, Tenn.-----
Knoxville, Tenn.-------
Louisville, Ky.--------
Memphis, Tenn.---------
Mobile, Ala.-----------
Montgomery, Ala.-------
Nashville, Tenn.-------

WEST SOUTH CENTRAL:
Austin, Tex.-----------
Baton Rouge, La.-------
Corpus Christi, Tex.---
Dallas, Tex.-----------
El Paso, Tex.----------
Fort Worth, Tex.-------
Houston, Tex.----------
Little Rock, Ark.------
New Orleans, La.-------
Oklahoma City, Okla.---
San Antonio, Tex.------
Shreveport, La.---------
Tulsa, Okla.-----------

MOUNTAIN:
Albuquerque, N. Mex.---
Colorado Springs, Colo.
Denver, Colo.----------
Ogden, Utah------------
Phoenix, Ariz.---------
Pueblo, Colo.----------
Salt Lake City, Utah---
Tucson, Ariz.----------

PACIFIC:
Berkeley, Calif.-------
Fresno, Calif.---------
Glendale, Calif.-------
Honolulu, Hawaii-------
Long Beach, Calif.-----
Los Angeles, Calif.----
Oakland, Calif.--------
Pasadena, Calif.*------
Portland, Oreg.--------
Sacramento, Calif.-----
San Diego, Calif.------
San Francisco, Calif.--
San Jose, Calif.-------
Seattle, Wash.---------
Spokane, Wash.---------
Tacoma, Wash.----------


1,174
140
276
34
56
95
55
78
34
99
84
186
37

628
84
45
44
125
129
57
40
104

1,244
37
39
41
166
28
101
245
45
244
80
124
50
44

474
46
21
143
21
99
30
56
58

1,599
12
26
33
59
86
490
72
37
132
65
111
184
33
122
71
66


611
66
144
13
22
51
30
36
18
75
51
85
20

329
35
26
23
62
71
26
26
60

633
23
15
20
89
13
49
114
25
118
42
66
32
27

308
30
14
101
13
52
20
40
38

1,005
9
13
27
26
56
305
52
27
87
36
64
103
20
80
56
44


Total 13,430 7,842 661 648

Cumulative Totals
including reported corrections for previous weeks

All Causes, All Ages ----------------------- 199,777
All Causes, Age 65 and over------------------- 116,327
Pneumonia and Influenza, All Ages------------- 9,908
All Causes, Under 1 Year of Age--------------- 10,141


Week No.

15


*Estimate based on average









Morbidity and Mortality Weekly Report


INVESTIGATIONAL VACCINES PROGRAM


The following has1 been communicated by the Lab-
oratory Branch of the Communicable Disease Center:


\ program has been established at the CDC to pro-
1ide vaccines that are needed for human immunization
but are not available from commercial sources. The
objective of the program is to provide qualified medical
investigators with a source of vaccines which have been
proven effective and safe. hut their applications are too
limited to sustain commercial production and distribution.
These steps are being taken on the recommendation of
The Public Health Service Advisory Committee on Immu-
nization Practice.
The first product that will be available in this pro-
gram is the pentavalent (ABCDE) botulinum toxoid,
aluminum phosphate adsorbed, that was developed by
Dr. George G. Wright and associates at the U.S. Army
Biological Laboratories, Fort Detrick. Frederick. Maryland.
The toxoid will be distributed as an Investigational
New Drug. Inquiries and requests for this item should be
addressed to:
Investigational Vaccines Program
Laboratory Branch
Communicable Disease Center
Atlanta, Georgia 30333
Suggestions will be considered regarding additional
prophylactic agents that meet the program objective
stated above and which might be considered for provision
by the Communicable Disease Center in the future.






ERRATUM, Vol. 15, No. 14, p. 117:


The issue of the MMWR for the week ending April 9, 1966,
is incorrectly numbered. On the front page in the upper
right corner the text should read Vol. 15, No. 14, instead
of Vol. 15, No. 10.


APRIL 16, 1966


THE MORBIDITY AND MORTALITY WEEKLY REPORT, WITH A CIRCULA-
TION OF 15,600. IS PUBLISHED AT THE COMMUNICABLE DISEASE
CENTER. ATLANTA. GEORGIA.
CHIEF. COMMUNICABLE DISEASE CENTER DAVID J. SENCER, M.D,
CHIEF. EPIDEMIOLOGY BRANCH A.D. LANGMUIR, M.D.
ACTING CHIEF. STATISTICS SECTION IDA L. SHERMAN. M.S.
EDITOR: MMWR D.J.M. MACKENZIE. M.B,
F.R. C P. E.
IN ADDITION TO THE ESTABLISHED PROCEDURES FOR REPORTING
MORBIDITY AND MORTALITY. THE COMMUNICABLE DISEASE CENTER
WELCOMES ACCOUNTS OF INTERESTING OUTBREAKS OR CASE INVES.
TIGATIONS WHICH ARE OF CURRENT INTEREST TO HEALTH OFFICIALS
AND WHICH ARE DIRECTLY RELATED TO THE CONTROL OF
COMMUNICABLE DISEASES. SUCH COMMUNICATIONS SHOULD BE
ADDRESSED TO:
THE EDITOR
MORBIDITY AND MORTALITY WEEKLY REPORT
COMMUNICABLE DISEASE CENTER
ATLANTA. GEORGIA 30333
NOTE: THE DATA IN THIS REPORT ARE PROVISIONAL AND ARE
BASED ON WEEKLY TELEGRAMS TO THE CDC BY THE INDIVIDUAL
STATE HEALTH DEPARTMENTS. THE REPORTING WEEK CONCLUDES
ON SATURDAY: COMPILED DATA ON A NATIONAL BASIS ARE RELEASED
ON THE SUCCEEDING FRIDAY.


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