TOXICITY ASSUMPTIONS MADE WITH NO DATA
1 In1 -
1 In 10,000 -
1 In 1,000,000 _
The Lnearized Multi-Stage Model makes assumptions on the adverse effects of low doses
of a chemical even though there are Insufficient data to support such assumptions.
The model takes dose-response Information based on high doses and assumes
that there Is the same relative adverse effect at low doses. However, there are
Insufficient data to support this assumption. The lower doses may,
In reality, result in different adverse effects or none at all.