Longitudinal Examination of Genetic Differential Susceptibility, Parenting, and Peers in Predicting Substance Use among ...

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Material Information

Title:
Longitudinal Examination of Genetic Differential Susceptibility, Parenting, and Peers in Predicting Substance Use among African American Youths
Physical Description:
1 online resource (96 p.)
Language:
english
Creator:
Costa, Elise T
Publisher:
University of Florida
Place of Publication:
Gainesville, Fla.
Publication Date:

Thesis/Dissertation Information

Degree:
Master's ( M.A.)
Degree Grantor:
University of Florida
Degree Disciplines:
Criminology, Law, and Society, Sociology and Criminology & Law
Committee Chair:
GIBSON,CHRIS L
Committee Co-Chair:
KROHN,MARVIN D
Committee Members:
FAGAN,ABIGAIL A

Subjects

Subjects / Keywords:
african -- american -- differential -- genetics -- gxe -- substance -- susceptibility -- use
Sociology and Criminology & Law -- Dissertations, Academic -- UF
Genre:
Criminology, Law, and Society thesis, M.A.
bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, terriorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract:
The purpose of this thesis was to examine propositions from Thornberrys interactional theory for parenting, peers, and substance use across developmental stages of early to late adolescents, while also advancing propositions about these associations by proposing and empirically testing genetic differential susceptibility hypotheses. The genetic differential susceptibility hypothesis suggests that particular genetic variants thought to place individuals at risk for engaging in antisocial behavior actually increase their sensitivity to social environments, both nurturing and harsh. Three waves of prospective longitudinal data (waves 2 through 4) taken from the Family and Community Health Study (FACHS) were analyzed to test hypotheses from four research questions that include 1) does structural adversity indirectly influence substance use through ineffective parenting? 2) at what developmental stage do parents and peers matter most for predicting substance use, 3) is the association between parenting and youths substance use conditioned by a childs degree of genetics sensitivity to his/her environment, and 4) if so, do gene X environment interactions vary by developmental stage. The analysis sample contains genetic information on DRD4 and 5HTTLPR, as well as complete data on 467 respondents from waves 2 through 4. Multivariate logistic regression models were estimated to predict a binary measure of substance use during mid-adolescents (waves 3) and again during late adolescence/early adulthood (wave 4). Peer substance had the most consistent statistically significant and positive association with substance use across waves. Parenting influences on substance use were marginal. Parent hostility measured at wave 2 exhibiting a significant and positive association with wave 3 substance use. Separate interactions between a genetic index and four parenting measures, as well as peer substance use, were non-significant, providing no support for a genetic susceptibility hypothesis. The implications of the findings for interactional theory and gene X environment research on substance use are discussed, several limitations are acknowledged, and future research directions are identified.
General Note:
In the series University of Florida Digital Collections.
General Note:
Includes vita.
Bibliography:
Includes bibliographical references.
Source of Description:
Description based on online resource; title from PDF title page.
Source of Description:
This bibliographic record is available under the Creative Commons CC0 public domain dedication. The University of Florida Libraries, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
Statement of Responsibility:
by Elise T Costa.
Thesis:
Thesis (M.A.)--University of Florida, 2014.
Local:
Adviser: GIBSON,CHRIS L.
Local:
Co-adviser: KROHN,MARVIN D.
Electronic Access:
RESTRICTED TO UF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE UNTIL 2016-05-31

Record Information

Source Institution:
UFRGP
Rights Management:
Applicable rights reserved.
Classification:
lcc - LD1780 2014
System ID:
UFE0046836:00001