Distinct Pattern of Walking Recovery following Therapeutic Interventions Post-Stroke

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Material Information

Title:
Distinct Pattern of Walking Recovery following Therapeutic Interventions Post-Stroke Responders Vs. Non-Responders
Physical Description:
1 online resource (177 p.)
Language:
english
Creator:
Patil, Shilpa
Publisher:
University of Florida
Place of Publication:
Gainesville, Fla.
Publication Date:

Thesis/Dissertation Information

Degree:
Doctorate ( Ph.D.)
Degree Grantor:
University of Florida
Degree Disciplines:
Rehabilitation Science
Committee Chair:
PATTEN,CAROLYNN
Committee Co-Chair:
HASS,CHRISTOPHER J
Committee Members:
ROSENBEK,JOHN CLYDE
PRESNELL,BRETT DOUGLAS
FREGLY,BENJAMIN J

Subjects

Subjects / Keywords:
gait -- recovery -- responder -- stroke
Rehabilitation Science -- Dissertations, Academic -- UF
Genre:
Rehabilitation Science thesis, Ph.D.
bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, terriorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract:
Following a staged intervention with 5 weeks of power training followed by 3 weeks of gait training we identified 2 distinct groups of individuals based on the improvement in their walking speed: responders and non-responders. Ernst in his review on stroke rehabilitation in 1990 had expressed an urgent need to design well-planned clinical trials aimed at finding the best treatment approach and discriminating potential responders. However, this issue has only recently been investigated. Stroke is one of the most leading causes of disability worldwide and leaves more than 67% of individuals who have walking impairment following stroke unable to achieve independent walking.Consequently, walking recovery is one of the most articulated goals in stroke rehabilitation.Moreover a large clinical trial recently showed that only about 52% of individuals post subacute stroke improve their walking function following intervention.Consequently, there is an urgent need to understand why some individuals respond to treatment to a greater extent and how this information can be used in clinics to the advantage of a clinician.   This dissertation informs us that individuals who respond have better lateral stabilization of their pelvis and are able to transfer weight from the paretic to the non-paretic leg more efficiently at baseline.Moreover, they achieve improvement in their walking speed following treatment by using restoration as well as compensation both proximally and distally whereas non-responders use intra-limb compensation by more proximal muscles and inter-limb compensation by the non-paretic leg. Finally, using a multivariate approach by a combination of Sure Independent Screening, Envelope model and Fischer Discriminant analysis we also developed a criterion based on 8 key gait measures at baseline which could a priori identify the potential responders.
General Note:
In the series University of Florida Digital Collections.
General Note:
Includes vita.
Bibliography:
Includes bibliographical references.
Source of Description:
Description based on online resource; title from PDF title page.
Source of Description:
This bibliographic record is available under the Creative Commons CC0 public domain dedication. The University of Florida Libraries, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
Statement of Responsibility:
by Shilpa Patil.
Thesis:
Thesis (Ph.D.)--University of Florida, 2013.
Local:
Adviser: PATTEN,CAROLYNN.
Local:
Co-adviser: HASS,CHRISTOPHER J.
Electronic Access:
RESTRICTED TO UF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE UNTIL 2015-12-31

Record Information

Source Institution:
UFRGP
Rights Management:
Applicable rights reserved.
Classification:
lcc - LD1780 2013
System ID:
UFE0045342:00001