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Dimorphic Gene Expression Before and After the Onset of Sexual Differentiation

Permanent Link: http://ufdc.ufl.edu/UFE0043832/00001

Material Information

Title: Dimorphic Gene Expression Before and After the Onset of Sexual Differentiation
Physical Description: 1 online resource (51 p.)
Language: english
Creator: Fernandez, Jennifer A
Publisher: University of Florida
Place of Publication: Gainesville, Fla.
Publication Date: 2011

Subjects

Subjects / Keywords: cluster -- hierarchical
Biology -- Dissertations, Academic -- UF
Genre: Zoology thesis, M.S.
bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, terriorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract: The process of sexual development encompasses two continuous phases: a hormone independent sexual determination phase, followed by a hormone dependent sexual differentiation phase. It is well known that androgen plays a central role in masculinizing the genitalia from its indifferent stage to its final form as the penis or clitoris. During this second phase, 5alpha-dihydrotestosterone acts on the androgen receptor (AR) to masculinize the genital tubercle. AR mRNA is detected at E12.5 and onward, AR protein is detected at E14 and embryo hormone production does not being until E13 Therefore, it can be deduced that E13.5 signifies the onset of the hormone dependent phase. The molecular mechanisms of sexual differentiation are largely unknown. The targets of the androgen receptor, and how these genes interact and react, and consequently resulting in the final form of the external genitalia, remain a mystery. To explore this subject we used a microarray and compared the transcriptomes of males and females at E13.5, the onset of sexual differentiation, and at E15.5, after the "androgen surge", to elucidate the key players responsible for the developmental fate of the genital tubercle.
General Note: In the series University of Florida Digital Collections.
General Note: Includes vita.
Bibliography: Includes bibliographical references.
Source of Description: Description based on online resource; title from PDF title page.
Source of Description: This bibliographic record is available under the Creative Commons CC0 public domain dedication. The University of Florida Libraries, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
Statement of Responsibility: by Jennifer A Fernandez.
Thesis: Thesis (M.S.)--University of Florida, 2011.
Local: Adviser: Cohn, Martin J.
Electronic Access: RESTRICTED TO UF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE UNTIL 2014-12-31

Record Information

Source Institution: UFRGP
Rights Management: Applicable rights reserved.
Classification: lcc - LD1780 2011
System ID: UFE0043832:00001

Permanent Link: http://ufdc.ufl.edu/UFE0043832/00001

Material Information

Title: Dimorphic Gene Expression Before and After the Onset of Sexual Differentiation
Physical Description: 1 online resource (51 p.)
Language: english
Creator: Fernandez, Jennifer A
Publisher: University of Florida
Place of Publication: Gainesville, Fla.
Publication Date: 2011

Subjects

Subjects / Keywords: cluster -- hierarchical
Biology -- Dissertations, Academic -- UF
Genre: Zoology thesis, M.S.
bibliography   ( marcgt )
theses   ( marcgt )
government publication (state, provincial, terriorial, dependent)   ( marcgt )
born-digital   ( sobekcm )
Electronic Thesis or Dissertation

Notes

Abstract: The process of sexual development encompasses two continuous phases: a hormone independent sexual determination phase, followed by a hormone dependent sexual differentiation phase. It is well known that androgen plays a central role in masculinizing the genitalia from its indifferent stage to its final form as the penis or clitoris. During this second phase, 5alpha-dihydrotestosterone acts on the androgen receptor (AR) to masculinize the genital tubercle. AR mRNA is detected at E12.5 and onward, AR protein is detected at E14 and embryo hormone production does not being until E13 Therefore, it can be deduced that E13.5 signifies the onset of the hormone dependent phase. The molecular mechanisms of sexual differentiation are largely unknown. The targets of the androgen receptor, and how these genes interact and react, and consequently resulting in the final form of the external genitalia, remain a mystery. To explore this subject we used a microarray and compared the transcriptomes of males and females at E13.5, the onset of sexual differentiation, and at E15.5, after the "androgen surge", to elucidate the key players responsible for the developmental fate of the genital tubercle.
General Note: In the series University of Florida Digital Collections.
General Note: Includes vita.
Bibliography: Includes bibliographical references.
Source of Description: Description based on online resource; title from PDF title page.
Source of Description: This bibliographic record is available under the Creative Commons CC0 public domain dedication. The University of Florida Libraries, as creator of this bibliographic record, has waived all rights to it worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law.
Statement of Responsibility: by Jennifer A Fernandez.
Thesis: Thesis (M.S.)--University of Florida, 2011.
Local: Adviser: Cohn, Martin J.
Electronic Access: RESTRICTED TO UF STUDENTS, STAFF, FACULTY, AND ON-CAMPUS USE UNTIL 2014-12-31

Record Information

Source Institution: UFRGP
Rights Management: Applicable rights reserved.
Classification: lcc - LD1780 2011
System ID: UFE0043832:00001

Full Text

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1 DIMORPHIC GENE EXPRESSION BEFORE AND AFTER THE ONSET OF SEXUAL DIFFERENTIATION By JENNIFER FERNANDEZ A THESIS PRESENTED TO THE GRADUATE SCHOOL OF THE UNIVERSITY OF FLORIDA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE UNIVERSITY OF FLORIDA 2011

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2 2011 Jennifer Fernandez

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3 ACKNOWLEDGMENTS I thank the chair and members of my supervisory committee for their mentoring, the members of the lab for their guidance and assistance, and the staff at UFGI for their help in completing my analysis. I thank my parents for their loving encouragement, which motivated me to complete my study.

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4 TABLE OF CONTENTS page ACKNOWLEDGMENTS ................................ ................................ ................................ ............... 3 LIST OF FIGURES ................................ ................................ ................................ ......................... 6 LIST OF OBJECTS ................................ ................................ ................................ ......................... 7 ABSTRACT ................................ ................................ ................................ ................................ ..... 8 CHAPTER 1 INTRODUCTION ................................ ................................ ................................ .................... 9 Introduction ................................ ................................ ................................ ............................... 9 Sexual Development ................................ ................................ ................................ ................. 9 Sexual Determination ................................ ................................ ................................ ........ 9 Genetic Control of GT Development ................................ ................................ .............. 10 Sexual Differentiation ................................ ................................ ................................ ..... 10 Testosterone, DHT and the Androgen Receptor ................................ ...................... 11 Disorders of Sexual Development ................................ ................................ ................... 12 Current Research ................................ ................................ ................................ .................... 12 2 METHODS ................................ ................................ ................................ ............................. 14 Animals ................................ ................................ ................................ ................................ ... 14 RNA Collection ................................ ................................ ................................ ...................... 14 Microarray ................................ ................................ ................................ .............................. 14 Analysis ................................ ................................ ................................ ................................ .. 15 3 RESULTS ................................ ................................ ................................ ............................... 18 Dimorphic Genes Before and After the Onset of Sexual Differentiation ............................... 18 Dimorphic Genes Before the Onset of Sexual Differentiation ................................ ........ 18 After the Onset of Sexual Differentiation ................................ ................................ ....... 19 Temporal Ch ange in Gene Expression ................................ ................................ ................... 21 Gene Expression in Females Before and After the Onset of Sexual Differentiation ................................ ................................ ................................ .............. 21 Gene Expression in Males Before and After the Onset of Sexual Differentiation ................................ ................................ ................................ .............. 23 Targets of the Androgen Receptor ................................ ................................ .......................... 25 Targets of The AR at the Onset of Sexual Differentiation ................................ .............. 25 Targets of the AR After the Onset of Sexual Differentiation ................................ .......... 26 4 DISCUSSION ................................ ................................ ................................ ......................... 39

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5 Dimorphically E xpressed Genes Before Onset of Sexual Differentiation ............................. 39 Activin type 1 receptor Acvr1 ................................ ................................ ........................ 39 Dimorphically Expressed Genes After the Onset of Sexual Differentiation .......................... 40 Fraser syndrome 1 Fras1 ................................ ................................ .............................. 40 Targets of Androgen Action ................................ ................................ ................................ ... 40 Androgen Targets at the Onset of Sexual Differentiation, E13.5 ................................ .... 41 Steroid 5 alpha reductase 3 Srd5a3 ................................ ................................ ........ 42 Gremlin 2 Grem 2 ................................ ................................ ................................ ... 43 Androgen Targets After the Onset of Sexual Differentiation, E15.5 .............................. 43 Insulin like growth factor 1 IGF 1 ................................ ................................ .......... 43 SPARC related modular cal cium binding Smoc1 ................................ .................. 44 Fras related protein 2 Frem2 ................................ ................................ ................ 44 5 CONCLUSION ................................ ................................ ................................ ....................... 46 LIST OF REFERENCES ................................ ................................ ................................ ............... 47 BIOGRAPHICAL SKETCH ................................ ................................ ................................ ......... 51

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6 LIST OF FIGURES Figure page 3 1 Gene ontology analysis corresponding to the dimorphically expressed genes in the male E13.5 versus female E13.5 comparison ................................ .......................... 28 3 2 Gene ontolo gy analysis corresponding to the dimorphically expressed genes in the male E13.5 versus female E13.5 comparison ................................ .......................... 29 3 3 Gene ontology analysis corresponding to the dimorphically expressed genes in the male E15.5 versus female E15.5 comparison ................................ .......................... 30 3 4 Gene ontology analysis corresponding to the dimorphically expressed genes in the male E15.5 versus female E15.5 comparison ................................ .......................... 31 3 5 Gene ontology analysis corresponding to the differentially expressed genes in the female E13.5 versus female E15.5 comparison ................................ ........................... 32 3 6 Gene ontology analysis corresponding to the differentially expressed genes in the female E13.5 versus female E15.5 comparison ................................ ........................... 33 3 7 Gene ontology analysis corresponding to the differentially expressed genes in the male E13.5 versus male E15.5 comparison ................................ ................................ 34 3 8 Gene ontology analysis corresponding to the differentially expressed genes in the male E13.5 versus male E15.5 comparison ................................ ................................ 35 3 9 Gene ontology analysis corresponding to the dimorphically expressed genes at E13.5 that are also targets of the androgen receptor. ................................ ..................... 36 3 10 Gene ontology analysis corresponding to the dimorphically expressed genes at E15.5 that are also targets of the androgen receptor. ................................ ..................... 37

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7 LIST OF OBJECTS Object page 3 1 Dimorphically expressed genes in the female versus male comparison at E13.5 ................................ ................................ ................................ ................................ .. 38 3 2 Hierarchical cluster: female versus ma le comparison at E13.5 ................................ ......... 38 3 3 Dimorphically expressed genes in the female versus male comparison at E15.5 ................................ ................................ ................................ ................................ .. 38 3 4 Hierarchical cl uster: female versus male comparison at E15.5 ................................ ......... 38 3 5 Differentially expressed genes in the female at E13.5 versus female at E15.5 ................. 38 3 6 Hierarchical cluster: female at E13.5 versus 15.5 ................................ .............................. 38 3 7 Differentially expressed genes in the male at E13.5 versus male at E15.5 ....................... 38 3 8 Hierarchical cluster: male at E13.5 versus 15.5 ................................ ................................ 38 3 9 Androgen responsive genes at E13.5 as a PDF document (.pdf file 10 KB) ..................... 38 3 10 Androgen responsive genes at E15.5 as a PDF document (.pdf file 7 KB) ....................... 38

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8 Abstract of Thesis Presented to the Graduate School of the University of Florida in Partial Fulfillment of the Requirements for the Master of Science DIMORPHIC GENE EXPRESSION BEFORE AND AFTER THE ONSET OF SEXUAL DIFFERENTIATION By Jennifer Fernandez December 2011 Chair: Martin Cohn Major: Zoology The process of sexual development encompasses two continuou s phases: a hormone independent sexual determination phase, followed by a hormone dependent sexual differentiation phase. It is well known that androgen plays a central role in masculinizing the genitalia from its indifferent stage to its final form as the penis or clitoris. During this second phase, 5alpha dihydrotestosterone acts on the androgen receptor (AR) to masculinize the genital tubercle. AR mRNA is detected at E12.5 and onward, AR protein is detected at E14 and embryo hormone production does not b eing until E13 Therefore, it can be deduced that E13.5 signifies the onset of the hormone dependent phase. The molecular mechanisms of sexual differentiation are largely unknown. The targets of the androgen receptor, and how these genes interact and react, and consequently resulting in the final form of the external genitalia, remain a mystery. To explore this subject we used a microarray and compared the transcriptomes of males and females at E13.5, the onset of sexual differentiation, and at E15.5, after tubercle

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9 CHAPTER 1 INTRODUCTION Introduction The external genitalia begin as a genital tubercle, which is an embryonic precursor to the penis or clit oris in the fully developed organism. The developmental mechanisms that lead the formation of the genital tubercle are beginning to be understood (1) however the downstream targets of androgen s, which lead to the virilization of this organ remain unknown The overarching aim of this study is to identify the genes that mediate sexual differentiation of the external genitalia. Sexual Development The central paradigm of sexual development cultivated by Jost (5) is that chromosomal sex leads to gonadal sex, which leads to phenotypic sex. Sexual Determination Sex determination is a genetic ( and hormone independent ) event, which determines the sex ual characteristics of an organism. Humans and other mammals have a XY sex determination system in which females a re homogametic, having a XX pair of sex chromosomes and males are heterogametic, having a XY pair of sex chromosomes ( 2 ). The Y chromosome carries the SRY gene, which encodes the SRY protein. A mutation or translocation of part of the SRY gene underlies so me of the earliest of disorders of sexual development ( see below ) including Swyer Syndrome (XY females with gonadal dysgenesis) and XX male syndrome (3). The expression of SRY is a determinant of the male phenotype and allows the proliferation of Sertoli c ells, which will release anti mullerian hormone (AMH) (4). AMH in turn causes the regression of the female urogenital primordium, otherwise known as the Mullerian duct s and plays a role in

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10 development of Leydig cells, which will produce androgens and lead into the second hormonal dependent phase of development of external genitalia in males (4). Genetic Control of GT Development Development of the genital tubercle is under genetic control, which involves tight coordination of proximodistal outgrowth, pat terning, and urethral tubulogenesis Several developmental regulators, such as homeobox containing Hox genes catenin signaling bone morphogenic protein s (BMP s ), sonic hedgehog (Shh) and fibroblast growth factors (Fgf) have been suggested to play an orchestrating role in the patterning and outgrowth of the genital tubercle before masculination (13 20). These genetic ally controlled morphogenetic process es are followed by androgen mediated virilzation of or estrogen mediated feminization of the genital tubercle to form the male and female external genitalia Sexual Differentiation Androgens play a vital role in the second phase of sexual development, sexual differentiation, which determines the phenotypic sex of the organism. Jost (5) performed several experiments, which determined that testicular hormones ultimately induce the male phenotype. Through the castration of male rabbits prior to phenotypic differentiation of the external genitalia, he found all resulting phenotypes to be female, concluding th at the male form was the induced phenotype that resulted from testicular hormones. He also deduced that there were two embryonic testicular hormones, AMH and androgens. A series of separate endocrinologic and embryo logic experiments proved testosterone t o be the hormone ultimately involved in masculinizing the male urogenital tract. Administration of anti androgen pharmacological agents during embryogenesis was

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11 shown to inhibit male development (6, 7). In another experiment, t estosterone was shown to imm ediately precede virilization in many species, exhibiting a cause and effect relationship (8). In female embryos, administration of a testosterone analogue was shown to induce male development of internal and external genitalia (9). Although much is known about the role of sex hormones in sexual differentiation, the genetic mechanism s by which the y ultimately induce the differentiation of the sexually indifferent genitalia remains un resolved. Testosterone DHT and the Androgen Receptor Testosterone is produ ced by the Leydig cells in the gonads beginning in the embryo at embryonic day (E) 13 and acts locally to prom ote maturation of spermatagonia Testosterone also is secreted into the circula tory system where it acts to masculinize the external genitalia ( 4). Testosterone can be converted to a more active form dihydrotestosterone (DHT) by 5 alpha reductase in the cell. This metabolite proves to be a much more potent agonist for androgen receptor activation, as it does not have the ability to be converted to estrodiol through the enzyme aromatase as testosterone can. Thus, DHT it is purely androgenic. Either of these androgenic hormones can bind to the androgen receptor (AR) in the cytoplasm of the cell. After binding, this hormone receptor complex translo cates into the nucleus and binds to androgen responsive element s (ARE s ) on DNA where it functions as a DNA binding transcription factor that regulates gene expression of downstream targets. Endocrine disruptors, like the pharmacological agent flutamide, c an bind to the AR and inactivate signaling thereby preventing the expression of downstream targets and therefore organogenesis due to androgenic factors (21). Testosterone is mainly responsible for development of the male primary sexual characteristics ( e.g., epididymis, vas deferens, and seminal vesicle ), whereas DHT

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12 induces the development of secondary sexual characteristics (e. g. the prostate a nd penis) If there is an impairment of testosterone or the androgen receptor during development, the abnormal ities can involve both the internal and external genitalia. If the impairment is only within the formation of DHT, only the external genitalia will be affected, resulting in female external genit al ia with male internal reproductive organs (2 2 ) Mutation of the AR gene, which lies on the X chromosome, will result in testicular feminization mutation (TFM) in mice and androgen insensitivity syndrome (AIS) in humans. This syndrome results in 46, XY karyotype individuals, which are phenotypic females with male g onads that result as a function of the SRY gene. As the Wolffian structures are hormone dependent they will generally be absent in such mutants the severity of which depends on the mutation. This is yet another description of how impairments in any step of the path of sexual development can lead to a disorder of sexual development. Disorders of Sexual Development Disorders of sexual development (DSD) refer to an extensive list of anomalies that result from deviations of the normal sexual development. Thes e deviations can be broken down into anomalies of the sex chromosomes, the gonads, the reproductive ducts, and the genitalia (10). The defects focused mainly on the abnormalities in the development of external genitalia and can include micropenis, clitorom egaly and hypospadias. Current Research Research in the field of sexual differentiation and organogenesis of the genital tubercle has focused mainly on the genetic mechanisms of development. Little is known about the molecular mechanisms that mediat e the masculinization process induced by androgens. Recently, Miyagawa et al ii performed a DNA microarray analysis to compare gene expression between male and female genital tubercle s at E15.5, a n early stage of

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13 genital tubercle differentiation The comple te results of this study are unpublished but a few genes were extracted and analyzed rtPCR and in situ hybridization using tissue from the ventral bilateral mesenchyme and urethral epithelium (11). Li et al. (2006) previously performed microarray analysis of genital tubercle development; however, the data presented only a list of genes that increased in E16 and E17 GT versus E14. In addition, these data were collected from cDNA arrays, which have been shown to have lower reproducibility and concordance amo ng platforms (12), and not Affymetrix. Hence a comparison cannot be made with these data ( 2 3). Our aim is to explore the dimorphically expressed genes at the onset of sexual development (E13.5), as well after the onset (E15.5) The genetic targets of the androgen receptor and how these genes interact to ultimately result in the male external genitalia are unknown. To explore this subject we used a microarray and compared the transcriptomes of males and females at E13.5, when sexual differentiation is ini tiated and at E15.5, after androgenic action has begun to virilize the male genitalia to elucidate the key players responsible for the development of the external genitalia To identify the downstream targets of the androgen receptor, we administered the anti androgen flutamide to the pregnant dams beginning at E12.5 through 14.5, a window during which a phenotypic and feminizing effect can be induced (21). Total RNA was taken at E13.5 and E15.5 to identify the androgen targets before and after sexual dif ferentiation. To identify which genes are involved in the maturation of the genital tubercle, we compared the two time points within each sex. Identification of the candidate genes for embryonic genital tubercle maturation and sexual differentiation will f acilitate further molecular and developmental studies of sexual differentiation.

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14 CHAPTER 2 METHODS Animals Timed pregnant CD1 mice (Harlan Laboratory) were sacrificed via by cervical dislocation. Embryos were collected at embryonic day (E) E13.5 and E15.5 ( stage was determined initially by the day of an appearance of vaginal plug as 0.5 days post conception ) The stage of development was confirmed by morphological examination using a dissecting microscope. Embryos were sacrificed by decapitation immediately after removal from the yolk sac. The sex of the pups was confirmed by determining the presence of ovaries or testes, and also by PCR of embryonic tail DNA for SRY and ZFY as described ( 24 ). Fetal GTs were examined to confirm normal morphology and then mic rodissected and stored in RNAlater (Cat. No. 76104, Q IAGEN Valencia, CA) at 4 C for total RNA isolation. RNA Collection Total RNA from the frozen samples was extracted using an RNeasy Plus Micro Kit y kit; Cat. No. 74034, Q IAGEN Valencia, CA) RNA concentration was determined on a Nanodrop Spectrophoto meter (Nano Drop Technologies, Wilmington, DE) and RNA integrity was evaluated by microfluidic analysis using the Agilent 2100 Bioanalyzer (Agilent T echnologies Inc. Palo Alto, CA). Microarray Samples for microarray analysis were prepared by isolation of RNA from genital tubercles of E13.5 and E15.5 male and female mice f rom the following treatment groups; untreated and corn oil treated females and un treated, corn oil treated, and flutamide

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15 treated males. Four litters were harvested for each treatment group, and 3 male and 3 female embryos were collected from each litter. The flutamide treated and vehicle treated timed pregnant CD 1 dams were gavaged w ith 150mg/kg/day of flutamide dissolved in 10% ethanol and vehicle (tocopherol stripped corn oil), or 3ul/g/day of the vehicle dissolved in 10% ethanol, respectively, once daily at noon from E12.5 through E14.5. For embryos sacrificed at E13.5, the timed p regnant CD 1 dams were gavaged once on E12.5 with either flutamide or vehicle. For the embryos sacrificed at E15.5, the timed pregnant CD 1 dams were gavaged on E12.5, E13.5 and E14.5 with either a succession of flutamide or vehicle. cDNA synthesis, cRNA s ynthesis, amplification, biotin labeling and chip hybridization was performed as described in the IVT Expression Kit (Ca. No. 901229; Affymetix) protocol using 200ng of total RNA for the reverse transcription to synthesize first strand cDNA. An in vitro tr anscription incubation time of 16hrs was used to synthesize biotin modified cRNA from double stranded cDNA templates. Biotin labeled product was hybridized onto a GeneChip Mouse Genome 430 2.0 Array, which contains 42102 probe sets. Staining and washing fo llowed the protocol (EukGEWSv4; Affymetrix) with GeneChip Fluidics Station 450. Analysis GeneChip Mouse Genome 430 2.0 Arrays (Affymetrix) were used for the expression analysis. Four independent samples were collected for each combination of sex, stage and condition, for a total of 40 gene chips and 120 independent samples. Each independent replicate is a pool of RNA from three mice. Library files and cell files were quantified using Affymetrix Expression Console. MAS 5 signal values were extracted.

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16 Contr before analysis. The remaining 31,109 probe sets were analyzed. To identify sexual dimorphisms in gene expression before and after the onset of sexual differentiation, and genes involved in maturation of each sex during sexual differentiation we examined multiple contrasts between untreated samples The following ANOVA model was fit: Y ij = + i + ij where Y ij is natural log transformed signal for condition i = (female at E13.5, female at E15.5, male at E13.5 and male at E15.5), and replicate j for all the untreated samples (n=16). Where is the overall mean, is condition, and is the error. In order to identify the genes involved in sexual differentiation the followi ng contrasts were performed: female at E13.5 versus female at E15.5, female at E13.5 versus male at E13.5, male at E13.5 versus male at E15.5, and male at E15.5 versus female at E15.5. A False Discovery Rate (FDR) was used to correct for multiple tests (25 ). Since this analysis is an initial screen for genes involved in sexual differentiation between sexes or temporally within a sex, we are most concerned with type II error (false negatives). Accordingly, all probes significant at a false discovery rate (F DR) of P < 0.05 were retained for further analysis (25). Probe sets differentially expressed among sexes (at least 1 of the contrasts above significant n=5691) are then candidates for regulation mediated by the androgen receptor For the treated samples (n=24), the following ANOVA model was fit: Y ij = + i + ij where Y ij is natural log transformed signal for treatment i = (vehicle treated female at E13.5, vehicle treated female at E15.5, vehicle treated male at E13.5 and vehicle treated male at E15.5, flutamide treated male at E13.5, and flutamide treated male at E15.5), and replicate j. Where is the overall mean, is the treatment, and is the error. In order to

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17 identify direct or indirect targets of the androgen receptor the following cont rasts were performed: vehicle treated female at E13 verses vehicle treated male at E13, vehicle treated female at E13 versus flutamide treated male at E13, vehicle treated female at E15 versus vehicle treated male at E15, vehicle treated female at E15 vers us flutamide treated male at E15, vehicle treated male at E13 versus flutamide treated male at E13, vehicle treated male at E15 versus flutamide treated male at E15. A False Discovery Rate (FDR) was used to correct for multiple tests. Accordingly, all prob es significant at a false discovery rate (FDR) of P < 0.05 were considered to be significantly targets of the androgen receptor. Probe sets differentially expressed for at least 1 of these contrasts were selected for further analysis (n=3027).

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18 CHAPTER 3 RESULTS Dimorphic Genes Before and After the Onset of Sexual Differentiation Dimorphic Genes Before the Onset of Sexual Differentiation There are 45102 probes sets are available on the Affymetrix 430 2.0 Mouse Chip. After the absent calls were removed, 31100 probe sets were detected on at least one of the 40 arrays T he expression of 5691 of those probe sets was significant ly different in the comparisons between untreated males and females at E13.5, untreated males and females at E15.5, untreated males at E13.5 and E15.5, and untreated females at E13.5 and E15.5 These 5691 probe sets represent those with significant differences in expression during sexual differentiation and maturation between sexes at each stage as shown with the contrasts: untreated males versus untreated females at E13.5 and E15.5, and temporally within a sex as shown with the contrasts: untreated males at E13.5 versus untreated males at E 15.5, and untreated females at E13.5 versus untreated females at E15.5 From the 5691 signifi cantly different probe sets expressed within the pair wise male (E13.5, E15.5), female (E13.5, E15.5) comparisons contrasting within sexes and between sexes 265 distinct genes, excluding duplicates, were significant between males and female genital tuber cles at E13.5 In analyzing the probe sets comparatively between males and females at this stage, the expression of 163 genes was significantly higher in males than in females, while the expression of the remaining 103 genes were significantly higher in f emales than in males ( Object 3 1 ). Thus, at E13.5 in the genital tubercle, 58% more genes were expressed at a level significantly higher in males than in females. These developmentally interesting genes included Cybr3, Ctnd1, Mib2, Daam1, Activinr1,

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19 Pak3, Fap, Egr2, Egfr, Slit3, Mib2, and Foxc1 In females, up regulated genes included Senp2 and Dab2 When clustered together by similarity in expression level using the LSmeans value, the hierarchical cluster analysis produced 10 clusters ( Object 3 2 ). The first two clusters as well as clusters 4,5,6 and 7, represent genes in which the expression levels in males were comparatively higher than that in females, and clusters 3, 8, 9 and 10, represent those in which the expression levels in females was comparati vely higher than that in males. In the clusters up regulated in males, Col17a1, Cyb5r3, and Mib2 presented in cluster1, Pak3, Egfr, Egr2, Foxc1 and Bmp pathway associated gene, Acvr1, presented in cluster 2. Within the female clusters, Senp2 presented in cluster 3.There were no genes known to be important in the development of other organ systems in clusters 4 through 10. The annotated genes were sorted into their biological function as guided by Affymetrix Mouse 430 2.0 annotation Gene Ontology terms. T he most dimorphic constituted 10% of the genes shown to be more highly expressed in males (Figure 3 1 ) while only 2% of genes more highly expressed genes in females had this bi o logical function (Figure 3 2 ). The remaining 28% of the genes upregulated in the females at E13.5, and 36% of the genes upregulated in the male s at E13.5, had no known function. After the Onset of Sexual Differentiation During mouse embryonic development, hormone production begins at E13 (2 7 29 ), and AR protein is detected at E14 ( 26 ), and so it is that by E14.5 the embryo is within the hormone dependent phase of sexual development. By E15.5, AR and its ligand DHT have been diffusing through the blood for a time that is sufficient to activate

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20 downstream targets that are responsible for the virilization of the genital tubercle ( 30 31 ) I investigated which genes are differentially expressed at this stage of development in order to determine which targets o f the AR are responsible for the developmental fate of the genital tubercle. From the 5691 significantly different probe sets expressed within the pair wise male (E13.5, E15.5) and female (E13.5, E15.5) comparisons, contrasting within sexes and between se xes 28 of those, excluding duplicates, were significant between males and females at E15.5 ( Object 3 3 ) In analyzing the probe sets comparatively between males a nd females at this stage, the expression of 20 genes was significantly higher in females than in males, while the expression of the remaining 8 genes was significantly higher in males than in females. In males at this stage, 8 genes were up regulated, and in females, 20 genes were up regulated in males Thus, at E15.5 in the genital tubercle, 60% more genes were expressed at a level significantly higher in females than in males These genes that were up regulated in females at E15.5 included Abcf3, Vamp3, Fras1, Eif2s 3x The genes that were up regulated in this comparison in males included mainly Y linked genes like Ddx3y When clustered together by similarity in expression level using the LSmeans value, the hierarchical cluster analysis produced 10 clust ers ( Object 3 4 ) The first 5 clusters consist of genes that are comparatively higher in males than in females. In the first cluster there were 6 genes, which consisted of Cox4i2, Eif2s3x, Zscan12, Abcf3, Kdm6a In the second cluster, the genes presented w ere Ssbp2, Tmem213, Vamp3, and Fras1 The third, fourth and fifth clusters consisted of Ncapd3, Tsc22d1 and Xist The

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21 fifth through tenth clusters consisted of genes that were comparatively higher in females than in males at E15.5 and they were Ddx3y, Uty and Gca The annotated genes were sorted into their biological function as guided by Affymetrix Mouse 430 2.0 annotation Gene Ontology terms The most dimorphic 20% of the genes shown to be more highly expressed in males ( Figure 3 3 ), while only 9% of gene s more highly expressed genes in females had this biological function ( Figure 3 4 ). There were also genes present in males that had biological function in the gories, of which no genes were present in these categories in females. The remaining 64% and 56% genes in the female / male comparison at E15.5, respectively had no known function. Temporal Change in Gene Expression To u nderstand the molecular events that occur during sexual differentiation, we examined the gene expression profiles of each gender at two time points, E13.5, before the onset of differentiation, and E15.5, when sexual differentiation is underway. We were particularly interested in identifying the genes that control maturation of the male and female genitalia Gene Expression in Females Before and After the Onset of Sexual Differentiation Pairwise comparisons of male (E13.5, E15.5) and female (E13.5, E15.5) genital tubercles which were contras t ed within sexes and between sexes, identified 5691 probe sets with significantly different express ion profiles P airwise comparisons of females at E13.5 versus females at E15.5 revealed 3968 distinct genes that are significant ly different ( Object 3 5 ). I n analyzing the probe sets comparatively between females at each stage,

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22 the expression of 2262 genes were significantly higher at E13.5 than at E15.5, while the expression of the remaining 1706 genes were significantly higher at E15.5 than at E13.5. Thus, at E13.5 in the genital tubercle, 25% more genes were expressed at a level significantly higher at E13.5 than at E15.5 Among the genes upregulated at E13.5 were collagens ( Col1a1, Col1a2, Col3a1, Col5a1, Col5a2 Col6a1, Col8a1, Col8a2, Col23a1 ), keratins ( krt6a, krt13, krt42, krt77, krt84 ), forkhead genes ( Foxc1, Foxf1a, Foxh1, Foxj2, Foxk1, Foxk2, Foxn1, Foxn2, Foxn3, Foxo3, Foxp1, Foxq1 ), DNA binding transcription factors, particularly homeobox genes ( Hoxa5, Hoxa9, Hoxa10, Hoxd13, Msx1, Meox2, Shox2, Pr rx1, Cux1, Hopx, Lhx5, Mkx ), fibronectin III domain encoding genes ( Fn1, Epha1, Epha3, Epha7, Ephx1 ), members of the TGF Beta superfamily of ligands ( Bmp2, Bmpr2, Bmp2k, Acvr1 ), Wnt signaling pathway genes ( Wnt2, Wnt5a, Wnt6, Wnt7a, Wnt9a, Wnt16, Frz1, Frz 2, Frz3), members of the protocadherin gene family, which is a subset of the cadherin family (Pcdh7, Pcdh9 Pcdhb9, Pcdh10, Pcdh12, Pcdh17 ), and other developmentally interesting genes ( Senp2, Senp3, Sumo3, Rhoa, Notch3, Jun, Dkk3, Hey2, Igf1, Fras1 ). When clustered together by similarity in expression level using the LSmeans value, the hierarchical cluster analysis produced 10 clusters ( Object 3 6 ) The first 4 clusters consist of genes that are comparatively higher at E15.5 than at E13.5. In the first clu ster some developmentally interesting genes exhibited were Epha1, Jag1, Ctnna1, Egfr, Efr3, Klf6, Acvr1, Ror1 Dkk3, Lrp10, Jak2, Fkbp7, Fkbp9, Abcd3, Cyb5, and Notch3 In the second cluster, some interesting genes presented were Foxc1, Foxj2, Foxk1, Fox o1, Foxq1, Epha3, Epha7, Col1a2, Col3a1, Col5a1, Col8a1, Col23a1, Wnt5a, Fkbp14, Sox2, Ar, Pak3, Jun, Shox2, Hey2, Igf1, Mkx, and Rhoq The third cluster

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23 contains Tgfbr2, Ephx1, Wnt9a, Fkbp10 Col1a1, Col5a2, and Col6a1 Cluster four contained many keratins (e.g., krt6a, krt13, krt84 ) along with Meox2 and Cadm3. The last cluster whose expression was comparatively higher at E15.5 than E13.5 was cluster five which contained a Wnt ligand, Rspo1, and genes involved in epidermal differentiation and cornification Hrnr, Dpt and Lor. Clusters six through ten contain genes that were more highly expressed at E13.5, before the onset of sexual development in females. In cluster six included Foxk2, Sox12, Hoxa9, Hoxd13, Fkbp4, Ryk, Msx2, Senp2, Senp3, and Sumo3 Example s of genes in cluster seven include Rac3 Fzd3, Hoxa5, Msx1, Fkbp3, Wnt6 and Actb Examples of genes contained in cluster eight are Wnt5a, Wnt7a, Senp6 and Foxf1a The genes expressed in cluster nine included Rhoa and Hoxa10 In the final cluster, ten, ex amples are Fras1 Hoxa10 and Tbx3 The annotated genes were sorted into their biological function as guided by Affymetrix Mouse 430 2.0 annotation Gene Ontology terms. Analysis of the genes that are significantly higher E13.5 than E15.5 females, the mos t dimorphic ontology group (Figure 3 5 ) whereas only 9% of the genes more highly expressed at E15.5 belong ed to this class (Figure 3 6 ) Comparisons of female genitalia at E13.5 and E15.5 also showed that 9% of the genes upregulated in E13.5 females and 27% of the genes upregulated at E15.5 had no known functio n Gene Expression in Males Before and After t he Onset of Sexual Differentiation From the 5691 significantly different probe sets expressed within the pair wise male (E13.5, E15.5), female (E13.5, E15.5) comparisons which were contrast ed within sexes and between sexes 885 of those, excluding duplicates, were significant between males at E13.5 and E15.5 ( Object 3 7 ). In analyzing the probe sets comparatively in males

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24 between E13.5 and E15.5, the expression of 614 genes were significantly higher at E13.5, while the expression of the remaining 271 genes were significantly higher at E15.5 than at E13.5. Thus, 56% more genes were expre ssed at a level significantly higher at E13.5 than at E15.5. These genes include Fkbp1b, Fkpb7, Fkbp9, Foxc1, Foxk2, Bmpk2 Jak2, Ptgr1, Igf1, Fap, Mkx, TGFBR2, Sox7, Sox9, Meis1, Meis2, Frem2, Fras1, Senp6, Lix1, Dlx1, Dlx2, Notch1, Hoxa9, Wnt6, Wnt7a, Pit x2, and Msx1. When clustered together by similarity in expression level using the LSmeans value, the hierarchical cluster analysis produced 10 clusters ( Object 3 8 ). The first five clusters consist of genes that are comparatively higher at E15.5 than at E1 3.5 in males. T he first cluster contained Fkbp7, Fkbp9, Bmp2k, Jak2 and Foxc1 The second cluster contained Mafb and Ifg1 followed by the third cluster of Sfrp2, Upk1b, Fap, Mk x Tgfbr2, Sox7 and four th cluster which contained Fbln7 C luster five contai ned three genes of which none were remarkable. Clusters six through ten contain genes whose expression intensities were comparatively higher at E13.5, or prior to the onset of sexual differentiation. These genes include; cluster six : Wnt6, Wnt7a, Msx1, Msx 2, Dlx1 ; cluster seven : Notch1, Hoxa9, Fkbp1b, Pitx2, Foxk2 ; cluster eight : Sox9, Tbx3 ; and cluster nine : Meis1, Meis2, Lix1, Senp6, Dlx2, Abce1, Frem2, and Fras. The annotated genes were sorted into their biological function as guided by Affymetrix Mous e 430 2.0 annotation Gene Ontology terms. Genes involved in the most dimorphic biological process es genes shown to be more highly expressed at E15.5 (Figure 3 7 ), while only 2% of genes more highly expressed genes at E13.5 had this bi ological function (Figure 3 8 ). The

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25 remaining 46% and 23% of the genes in the E13.5 and E15.5 male comparison respectively had no known function Targets of the Androgen Receptor Targets of The AR at the Ons et of Sexual Differentiation Androgen signaling, mediated by AR and its ligand s testosterone and DHT, masculinizes the genital tubercle resulting in the formation of a penis. The direct and indirect targets of the ligand receptor complex in the genital tub ercle are largely unknown. The pharmacological agent flutamide acts as an anti androgen by directly binding to and blocking the AR ( 21 ), and was used in these studies to antagonize AR signaling AR mRNA is not known to be present in the embryo until after E12.5 ( 28 ), and androgen production begins at E13 (2 7 29 ) shortly after Leydig cell differentiation Given that AR protein is not detected until E14 (26), we hypothesized that antagonism of AR prior to this stage would have minor, if any, effects on the genitalia To test this hypothesis, we asked which of the 5691 genes that exhibited sexual dimorphism in untreated males (E13.5, E15.5) versus untreated females (E13.5, E15.5) when contrast ed within sexes and between sexes, were targets of AR. From thos e that showed dimorphism between males and females at both stages (5691 genes) 3026 genes also presented as significantly different within the flutamide comparisons described below To identify targets (direct or indirect) of AR in E13.5 genital tubercl es a series of paired comparisons were performed A female control ( corn oil treated ) versus male control comparison at E13.5 was carried out to identify sex specific differences in the context of the corn oil vehicle To identify which of these sex speci fic differences were due to AR activity, a female control versus male flutamide treated comparison at E13. 5

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26 was performed. We therefore searched for genes that were significantly different in the first ( control ) comparison s but were then not differentially expressed in the second ( male flutamide : female vehicle) comparison We predicted that this experiment would determine if there is an interaction between the pharmacological agent, and anti androgen receptor blocker flutamide, and genes present and invol ved in sexual differentiation at its onset. The comparison between female and male control mice at E13.5 yielded 62 genes Of those 62 genes, 39 were then not significant in the comparison between female corn oil treated and male flutamide treated at E 13.5. Genes present in this comparison include Grem2, Rab40b, Casp6, and Srd5a3 ( Object 3 9 ) The data suggest that these 39 genes are either direct or indirect targets of AR. The annotated genes were sorted into their biological function s using Affymetri x Mouse 430 2.0 annotation Gene Ontology terms (Figure 3 9). The largest number of genes order we then The remaining 34% of the genes in the comparison between male and female controls at E13.5, that were then were not significant in the comparison when the male was treated with flutamide at the same stage, had no known function Targets of the AR After the Onset of Sexu al Differentiation In parallel to the flutamide comparison performed at the onset of sexual differentiation, we compared female control versus male control genitalia at E15.5 to identify sex

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27 specific differen c es in the presence of corn oil. We next compar ed female control s versus male flutamide treated comparison at E15.5. This was followed by a cross comparison of these two data sets to identify genes that respond to AR antagonism The comparison between female and male con trol mice at E15.5 yielded 49 genes Of those 49 genes, 34 were then not significant in the comparison between female corn oil treated and male flutamide treated at E15. 5, suggesting that these 34 genes are androgen responsive Genes present in this pool include Frem2, Igf1, Eps15, Tagln3, Smoc1, and Rhoa ( Object 3 10 ) The annotated genes were sorted into their biological function as guided by Affymetrix Mouse 430 2.0 annotation Gene Ontology terms (Figure 3 10). The largest number of genes fell into the The remainder of the genes categorized T he remaining 46% of the genes that presented in the comparison between male and female controls at E15.5, and then were not significant in the comparison when the mal e was treated with flutamide at the same stage, had no known function

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28 Figure 3 1 Gene ontology analysis corresponding to the dimorphically expressed genes in the male E13.5 versus female E13.5 comparison. These depict the genes more highly expressed in males in this comparison.

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29 Figure 3 2. Gene ontology analysis corresponding to the dimorphically expressed genes in the male E13.5 versus female E13.5 comparison. These depict the genes more highly expressed in females in this comparison.

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30 Figure 3 3 Gene ontology analysis corresponding to the dimorphically expressed genes in the male E15.5 versus female E15.5 comparison. These depict the genes more highly expressed in males in this comparison.

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31 Figure 3 4. Gene ontology analysis corresponding t o the dimorphically expressed genes in the male E15.5 versus female E15.5 comparison. These depict the g enes more highly expressed in males in this comparison.

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32 Figure 3 5 Gene ontology analysis corresponding to the differentially expressed genes in th e female E13.5 versus female E15.5 comparison. These depict the genes more highly expressed in females at E13.5.

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33 Figure 3 6. Gene ontology analysis corresponding to the differentially expressed genes in the female E13.5 versus female E15.5 comparison. These depict the genes more highly expressed in females at E15.5.

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34 Figure 3 7 Gene ontology analysis corresponding to the differentially expressed genes in the male E13.5 versus male E15.5 comparison. These depict the genes more highly expressed in ma les at E1 5 .5. Immune related molecules 5% ECM/cell adhesion and tissue remodeling 4% Signaling transduction 9% Enzyme/ amino acid and protein metabolism 13% Transport proetin 10% Ion Transport 6% Carbohydrate metabolism 5% Transcriptional factors 9% Cytoskeleton protein 2% Cell proliferation, differentiation and apoptosis 7% Function unknown 23% Chromatin regulation and translation 3% DNA repair/modification 1% Cell Cycle 3%

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35 Figure 3 8. Gene ontology analysis corresponding to the differentially expressed genes in the male E13.5 versus male E15.5 comparison. These depict the genes more highly expressed in males at E1 3 .5. Immune related molecules 3% ECM/cell adhesion and tissue remodeling 2% Signaling transduction 4% Enzyme/ amino acid and protein metabolism 6% Transport proetin 2% Ion Transport 2% Carbohydrate metabolism 1% Transcriptional factors 11% Cytoskeleton protein 1% Cell proliferation, differentiation and apoptosis 5% Function unknown 46% Chromatin regualation and translation 8% DNA repair/modification 2% Cell Cycle 7%

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36 Figure 3 9 Gene ontology analysis corresponding to the dimorphically expressed genes at E13.5 that are also targets of the androgen receptor.

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37 Figure 3 10. Gene ontology analysis corresponding to the dimorphically expressed genes at E15.5 that are also targets of the androgen receptor.

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38 Object 3 1. Dimorphically expressed genes in the female versus male comparison at E13.5 as a PDF document (.pdf file 90 KB) Object 3 2. Hierarchical cluster: female versus male comparison at E13.5 as a PDF document (.pdf file 6.5 MB) Object 3 3. Dimorph ically expressed genes in the female versus male comparison at E15.5 as a PDF document (.pdf file 45 KB) Object 3 4. Hierarchical cluster: female versus male comparison at E15.5 as a PDF document (.pdf file 2.4 MB) Object 3 5. Differentially expressed gen es in the female at E13.5 versus female at E15.5 comparison as a PDF document (.pdf file 754 KB) Object 3 6. Hierarchical cluster: female at E13.5 versus 15.5 as a PDF document (.pdf file 19 MB) Object 3 7 Differentially expressed genes in the male at E13.5 versus male at E15.5 comparison as a PDF document (.pdf file 176 KB) Object 3 8. Hierarchical cluster: male at E13.5 versus 15.5 as a PDF document (.pdf file 17.2 KB) Object 3 9. A ndrogen responsive genes at E13.5 as a PDF document (.pdf file 10 KB) Object 3 10. A ndrogen responsive genes at E15.5 as a PDF document (.pdf file 7 KB)

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39 CHAPTER 4 DISCUSSION The objective of this study was to identify genes dimorphically expressed between males and females at key stages of sexual development, and to ident ify possible targets of androgen receptor during the hormone dependent phase of sexual differentiation. Below I discuss the significance of a subset of genes that are known have roles in other developmental processes and diseases. Dimor phically Expressed Genes Before Onset of Sexual D ifferentiation Activin type 1 receptor Acvr1 These receptors transduce signals for a variety of members of the transforming growth factor beta superfamily of ligands including AMH, activin, bone morphogenic proteins (BMPs) and Nodal (32). As expected due to its relation with AMH, this gene is upregulated in males at E13.5. This gene may also hint as to why there is a large discrepancy between the quantity of dimorphically expressed genes at E13.5 and E15.5. Patterning of ext ernal genitalia is under genetic control in males and females until around E15.5 in the mouse (30), after which morphological changes due sexual differentiation are first seen. This could account for the difference in number of dimorphically expressed gen es between females and males at E13.5, and females and males at E15.5 (265 versus 28, respectively). This idea is supported by the presence of the Tgf beta receptor, Acvr1 Tgf beta genes have been implicated in genital tubercle patterning and outgrowth; f or example, Bmp7 expression is located in the urethral epithelium, and Bmp2 and Bmp4 are expressed in the mesenchyme at this stage (16).

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40 Dimorphically Expressed Genes After the Onset of Sexual D ifferentiation Fraser syndrome 1 Fras1 The Fras 1 gene enco des a membrane protein that belongs to the FRAS1 family. This extracellular matrix protein is thought to be required for maintaining the integrity of the skin epithelium and is expressed mainly in sites of epithelial mesenchymal interactions. The protein l ocalizes to the basement membrane, and plays a role in epidermal dermal interactions during morphogenetic processes. Mutations in this gene Interestingly, Fraser syndrome is characterized by developmental abnormalities including malformations in the genitalia. In the microarray analysis, this gene is expressed at a level significantly higher in males and females at E13.5 as compared to E15.5, as depicted in the temporal co mparisons. It is also expressed at a level significantly higher in females at E15.5 compared to males at E15.5. Fras1 has been shown to down regulate BMP4 in the mesonephric duct ( 33 ). At E14.5, BMP4 is expressed in the mesenchyme surrounding the urethral plate in the genital tubercle ( 16 ), although its expression at E15.5 in the genital tubercle has yet to be published. The absence of Fras1 in males at E15.5 would suggest that BMP4 in the genital tubercle would be expressed at higher level and could indica te morphological remodeling. Targets of Androgen Action The targets of androgen action during formation of secondary sex characteristics are generally unknown. The aim of this investigation was to implicate target genes of androgen androgen receptor compl ex through the use of anti androgen flutamide. These are genes implicated as androgen targets at the onset of sexual differentiation.

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41 Androgen Targets at the Onset of Sexual D ifferentiation, E13.5 In the untreated comparisons, we detected a higher number o f dimorphically expressed genes (female versus male at E13.5 produced 265 genes: female versus male at E15.5 produced 28 genes) than in the parallel corn oil comparisons (female versus male at E13.5 produced 62 genes: female versus male at E15.5 produced 4 9 genes). Thus, corn oil alone reduces the number of differences in gene expression between males and females. The action of phytoestrogens can serve as a possible explanation for the difference in the number of dimorphically expressed genes. Phytoestroge ns are plant derived xenoestrogens that are proposed to possess hormone like properties in humans and other mammals, i.e., mimicking natural hormones, inhibiting the action of hormones, and inducing abnormal gene expressions. Exogenous estrogenic compounds that bind to the estrogen receptors (ERs) can block or alter endogenous estrogen functions via an ER mediated response, in reproductive and developmental stages. ( 34 ) This hypothesis is reinforced by the phytoestrogen genistein, which has been shown to in duce hypospadias in mice ( 35 ), as does the administration of exogenous estrogens in utero ( 36 ). Conversely, in ERKO mouse models, the adult females are partially masculinized, presenting with an elongated os clitoris ( 37 ). Along with providing evidence of phenotypic deviations due to modification of ER activation, this also disproves the traditional belief that androgens are necessary for masculinization of the male external genitalia, and in the absence of androgen the default female state will persist. In stead, a balance between androgens and estrogens are necessary for the proper morphology of adult external genitalia. The possible action of phytoestrogens in the corn oil experiments could have increased ER signaling in males, making their downstream ge ne expression patterns more similar to that of a female, thereby resulting in a decreased number of significantly

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42 different genes. This can be viewed by the untreated comparisons at E13.5 presenting with 265 significantly different genes and the corn oil c omparisons at E13.5 presenting with 62 significantly different genes. Conversely, the phytoestrogens could have increased the expression of ER targets to a level that would make genes that were not significantly different in the untreated experiments, then significantly different in the corn oil experiments. This can be viewed by the untreated comparisons at E15.5 presenting with 28 significantly different genes, and the corn oil comparisons at E15.5 presenting with 49 significantly different genes. Validat ion of these findings could include qPCR of an identified a gene whose expression was significantly different in the untreated comparison and not significant in the corn oil treated comparison at E13.5 and E15.5. Or, in a analogous fashion, identify the ge nes that were not present in the untreated comparisons and which were then present in the corn oil experiments to identify the genes are possibly antagonized by ER activation. Steroid 5 alpha reductase 3 Srd5a3 The Srd5a3 gene encodes an enzyme involved in the production of DHT from testosterone, and thus is involved in the maintenance of the androgen androgen receptor activation pathway ( 38 ). It is also necessary for the N linked glycosylation of proteins. Defects in SRD5A3 are the cause of congenital di sorder of glycosylation type 1Q in humans, which cause a range of abnormalities mainly due to the metabolic absence of glycosylated proteins. SRD5A3 sequence predicts a steroid 5a reductase domain, and mutation of the SRD5A2 gene in human causes male pseud ohermaphroditism resulting from an enzymatic block of the conversion of testosterone to DHT ( 39 ). Still, biochemical and clinical investigations in the patients with SRD5A3 mutations displayed

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43 no abnormal sexual abnormalities that would have suggested a pr imary defect of steroid metabolism ( 40 ). Further investigation will have to be performed to understand the role of Srd5a3 in sexual development. Gremlin 2 Grem 2 A related Gremlin gene, Grem1 is an antagonist of Bmp2 and Bmp4, which are both localized to the mesenchyme of the genital tubercle from E11.5 14.5, and are also implicated in proliferation and outgrowth of the genital tubercle. BMP2 and BMP4 are possible downstream targets of Shh, and in its absence are down regulated resulting in an increase in apoptosis in the genital tubercle ( 16 ). Through this gene expression analysis, Grem2 is implicated as a possible downstream target of androgen receptor, and if, like Grem1, it is an antagonist of Bmp2 and 4, it may play a role in regulating organogenesis, patterning, and tissue differentiation. This AR mediated inhibition of Bmp2 and 4 would allow for proliferation and outgrowth of the genital tubercle in males. It has been shown that suppression of BMP signaling through mutations of the receptor Bmpr1a ha s resulted in reduced apoptosis, which reinforces this hypothesis (41) Unfortunately, Grem2 knockout mouse has yet to be developed, so this hypothesis cannot be directly tested. The upstream disruption of Grem2 via anti androgens provides an intriguing ex planation for congenital birth defect localized to the external genitalia. Androgen Targets After the Onset of Sexual Differentiation E15.5 Insulin like growth factor 1 IGF 1 Igf1 is a n endogenous activator of the AKT signaling pathway, a stimulator of cell growth and proliferation, and a potent inhibitor of programmed cell death. Igf1 has been implicated in the embryo as necessary for proper growth of Sertoli and androgen producing Leydig cells through its ability to stimulate cell growth and proliferat ion ( 42 ).

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44 An AR/ Ifg1 positive feedback system has also been identified in prostate cells but it has never been implicated in genital development ( 43 ). As a possible target of the AR, the down regulation of Igf1 through anti androgens during sexual developm ent is an interesting topic that will need to be address further to elucidate its possible role in masculinizing the genital tubercle. SPARC related modular calcium binding Smoc1 Smoc 1 is a matricellular protein possibly involved in angiogenesis as well as growth factor signaling, proliferation, and migration in the embryo. As a matricellular protein, it has the capability to interact with hormones, cell surface receptors and other bioeffector molecules ( 44 ). Smoc1 is expressed in the murine fetal gonads beginning at E11.5 through E15.5, but its expression has not been characterized in the genital tubercle ( 45 ). Further work will have to be done to see if Smoc1 is implicated in the morphologic changes necessary for development and virlization of the geni tal tubercle. Fras related protein 2 Frem2 Frem2 like Fras1 that was expressed temporally in males and females and dimorphically at E15.5, encodes a membrane protein that belongs to the FRAS1 family. It plays a role in epidermal dermal interactions duri ng morphogenetic processes. Unlike Fras1 Frem2 loss of function experiments have resulted in defects in developmental events associated with coordinated migrations and cellular rearrangements of all three germ layers. This suggests that Frem2 may provide a substrate for rearrangements during embryogenesis by altering the extracellular matrix. Frem2 is expressed during development and precedes morphogenetic rearrangements in many tissues, with its loss leading to defects of these tissues ( 4 6 ). With Frem2 b eing implicated as a target of AR in the genital tubercle during sexual differentiation, in conjunction with its roll of providing

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45 a foundation for tissue rearrangements in embryogenesis, it is an interesting candidate for masculinization of the tubercle.

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46 CHAPTER 5 CONCLUSION Taken together the results presented here are consistent with the idea that the formation of male and female external genitalia is not a binary switch; it is a continuum from absolute male to absolute female mediated by differential r egulation of hundreds of genes While the early establishment of chromosomal sex may define male or female, the manifestation of phenotypic sex largely involves the regulation of genes important in key cellular processes rather than broad pattern formatio n. In identifying the genes that are dimorphically expressed at key stages in sexual development, and differentially expressed within sexes during sexual development, than maybe we can understand the continuum fully, and what causes the deviations from abs olute male and absolute female. This gene expression analysis lays a foundation for further study and identification of the interaction between the genes differentially expressed in so that we may understand the molecular mechanisms within the androgen d riven, morphological conversion from indifferent genital tubercle to phenotypic male.

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47 LIST OF REFERENCES 1. Cohn MJ. (2011) Development of the external genitalia: conserved and divergent mechanisms of appendage patterning Dev Dyn. 240(5):1108 15 2. Stephen G. Brush. Nettie M. Stevens and the Discovery of Sex Determination by Chromosomes Isis Vol. 69, No. 2 (Jun., 1978), pp. 162 172 3. Entrez Gene: SRY sex determining region Y. Gene ID: 6736 4. Wilson J.D., Griffin, J.E., George, F.W., Leshin M. (1983) The End ocrine Control of Male Phenotypic Development. Aust. J. Biol. Sel., 36, 101 128 5. Jost, A. (1953) Problems of fetal endocrinology. The gonadal and hypophyseal hormones Recent Progr. Hormone Res. 8 : 379 418 6. Goldman, S.S. (1971) Production of hypospadias in the rat by selective inhibition of fetal testicular 17 hydroxylase. Endocrinology 88, 527 31 7. Neumann, F., Berswordt Wallrabe, R., von, Elger, W., Steinbeck, H., Hahn, J.D., and Kramer, M. (1970) Aspects of androgen dependent events as studied by ant iandrogens. Recent Prog. Hrom. Res. 26, 337 410 8. Wilson, J.D., and Siiteri, P.K. (1973) Developmental pattern of testosterone synthesis in the fetal gonad of the rabbit. Endocrinology 92, 1182 91 9. Shultz, F.M. and Wilson, J.D. (1974) Virilization of the wolffian duct in the rat fetus by various androgens. Endocrinology 94, 979 86 10. Consortium on the Management of Disorders of Sex Development. Clinical Guidelines. 1st ed. Rohnert Park, CA: Intersex Society of North America; 2006 11. Nishida, H., et al. ( 20 08 ) Gene expression analyses on embryonic external genitalia: identification of regulatory genes possibly involved in masculinization processes. Congenit. Anom. (Kyoto) 48: 63 67 12. Woo Y, Affourtit J, Daigle S, Viale A, Johnson K, Naggert J, Churchill G. ( 2004) A comparison of cDNA, oligonucleotide, and Affymetrix GeneChip gene expression microarray platforms J Biomol Tech. 15(4):276 84. 13. Yamaguchi TP, Bradley A, McMahon A P,Jones S.A (1999) Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development; 126: 1211 e23 14. Haraguchi R, Suzuki K, M urakami R, Sakai M, Kamikawa M, Kengaku M, et al. (2000) Molecular analysis of external genitalia formation: the role of fibroblast

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48 growth factor (Fgf) genes during genital tubercle formation Development; 127: 2471 e9. 15. Haraguchi R, Mo R, Hui C, Motoyama J, Makino S, Shiroishi T, et al. (2001) Unique functions of Sonic hedg ehog signaling during external genitalia development. Development; 128: 4241 e50. 16. Perriton CL, Powles N, Ch iang C, Maconochie MK, Cohn MJ. (2002) Sonic hedgehog signaling from the urethral epithelium controls external genital development Dev Biol; 247: 26 e46. 352 Y. 17. Suzuki K, Bachiller D, Chen YP, Kamikawa M, Ogi H, Haraguchi R, et al. (2003) Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling Development 130: 6209 e20 18. Yamada G, Suzuki K, Haraguchi R, Miyagawa S, Satoh Y, Kamimura M, et al. (2006) Molecular genetic cascad es for external genitalia formation: an emerging organogenesis program. Dev Dyn 235:1738 e52. 19. Wilhelm D, Koopman P. (2006) The makings of maleness: towards an integrated view of male sexual development. Nat Rev Genet 7: 620e31. 20. Lin C, Yin Y, Long F, Ma L. (2008) Tissue specific requirements of beta catenin in external genitalia development. Development 135:2815e25. 21. Silversides, D. W., Pric e, C. A., and Cooke, G. M. (1995) Effects of short term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice. Can. J. Physiol. Pharm. 73: 1582 1588. 22. Barsoum I, Yao HH. ( 2006 ) The road to maleness: from testis to Wolffian duct. Trends Endocrinol Metab. Aug 17(6):223 8 23. Li et al., J. Li, E. Willingham and L.S. Baskin, (2006) Gene expression profiles in mouse urethral development BJU Int. 98 pp. 880 885 24. Hogan, B.L.M, Beggington, R., Costantini, F., Lacy, E., 1994. Manipulating the Mouse Embryo. A Laboratory Manual. Cold Spring Harbor Laborator y Press, Cold Spring Harbor, NY. 25. Benjamini, Y., Hochberg, Y., ( 1995 ) Controlling the false discovery rate a practical and powerful approach to multiple testing J. R. Stat. Soc., Ser. B Stat. Methodol. 57, 289 300.

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49 26. Agras K, Willing ham E., Liu B., Baskin LS. (2007) Ontogeny of Andr ogen Receptor and Disruption of Its mRNA Expression by Exogenous Estrogens During Morphogenesis of the Genital Tubercle J Urol.; 177(2):799. 27. Ikeda, Y., Shen, W. H., Ing raham, H.A., Parker, K.L., (1994) Developmental expression of mouse steroidogenic fact or 1, an essential regulator of the steroid hydroxylases Mol. Endocrinol. 8, 654 662 28. Crocoll A, Zhu CC, Cato AC, Blum M. (1998) Expression of androgen receptor mRNA during mouse embryogenesis Mech Dev. 72:175 178 29. Gondos, B. (1980) Development and di fferentiation of the testis and male reproductive tract. In: Testicular Development, Structure and Function (eds A. Steinberger & B. Steinberger), pp. 3 20. Raven Press, New York. 30. Suzuki, K., Ogino, Y., Murakami, R., Satoh, Y., Ba chiller, D., and Yamada,G (2002) Embryonic development of mouse externalgenitalia: insights into a unique mode of organogenesis. Evol. Dev. 4:133 141. 31. Miyagawa, S., et al. ( 2009b ) Genetic interactions of the androgen and Wnt/beta catenin pathways for the masculinization of exter nal genitalia. Mol.Endocrinol. 23: 871 880. 32. Cancer Genome Anatomy Project. National Cancer Institute. World Wide Web (URL: http://cgap.nci.gov). [July 2011] 33. Pitera JE, Scambler PJ, Woolf AS. (2008) Fras1, a basement membrane associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli. Hum Mol Genet. Dec 15;17(24):3953 64 34. Korach KS, Chae K, Gibson M, Curtis S. (1991) Estrogen receptor stereochemistry: ligand binding and hormonal responsiveness Steroids 56 :263 270. 35. Vilela ML, Willingham E, Buckley J, Liu BC, Agras K, Shiroyanagi Y, et al. (2007) Endocrine disruptors and hypospadias: role of genistein and the fungicide vinclozolin Urology 70:618 621 36. Kim K S, Torres CR jr, Yuc el S, et al. (2004) I nduction of hypospadias in a murine model by maternal exposure to synthetic estrogens Environ Res 94: 267 275 37. Yang JH, Menshenina J, Cu na GR, Place N, Baskin LS. (2010) Morphology of mouse external genitalia: implications for the ro le of estrogen in sexual dimorphisms of the mouse genital tubercle. J Urol 184: 1604 1609

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50 38. Uemura, M., Tamura, K., Chung, S., Honma, S., Okuyama, A., Nakamura, Y., and Nakagawa, H. (2008). Novel 5 alpha steroid reductase (SRD5A3, type 3) is overexpressed i n hormone refractory prostate cancer Cancer Sci. 99, 81 86. 39. Andersson, S., Berman, D.M., Jenkins, E.P., and Russell, D.W. (1991). Deletion of steroid 5 alpha reductase 2 gene in male pseudohermaphroditism. Nature 354, 159 161. 40. Cantagrel V, Lefeber DJ, Ng BG, Guan Z, Silhavy JL, Bielas SL, Lehle L, Hombauer H, Adamowicz M, Swiezewska E, De Brouwer AP, Blmel P, Sykut Cegielska J, Houliston S, Swistun D, Ali BR, Dobyns WB, Babovic Vuksanovic D, van Bokhoven H, Wevers RA, Raetz CR, Freeze HH, Morava E, Al Gazali L, Gleeson JG. ( 2010 ) SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder Cell 142(2):203 17. 41. Suzuki K, Bachiller D, Chen YP, Kamikawa M, Ogi H, Haraguchi R, Ogino Y, Minami Y, Mishina Y, Ahn K, Crenshaw EB 3rd, Yamada G. (2003) Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling [corrected]. Development. 130(25):6209 20 42. Baker J, Hardy MP, Zhou J, Bondy C, Lupu F, Bellv AR, Efstratiadis A. (1996) Effects of an Igf1 gene null mutation on mouse reproduction Mol Endocrinol. 10(7):903 18. 43. Yanase T, Fan W. (2009) Modification of androgen receptor function by IGF 1 signaling implications in the mechanism of re fractory prostate carcinoma Vitam Horm. 80:649 66 44. Bornstein P. ( 200 9 ) Matricellular proteins: an overview. Matrix Biol. (7):555 6 45. Pazin DE, Albrecht KH. (2009) Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and rep roductive tract differentiation. Dev Dyn. (11):2877 90. 46. Timmer JR, Mak TW, Manova K, Anderson KV, Niswander L. (2005) Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene Proc Natl Acad Sc i U S A. (33):11746 50.

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51 BIOGRAPHICAL SKETCH Jennifer Angelica Fernandez was born in 1986 in Monterey, California. The youngest of two children, she grew up in a military household, moving across the world and finally settling in Melbourne Florida. She earned her B achelor of Science in Integrative Biology the University of Florida in 2008. Upon completion of her b achelor degree she entered a m aster s degree program in Zoology also at the University of Florida. A short year and a half later she pree mptively began a Doctorate of Medical Dentistry program at the University of Pennsylvania, only to return a year later to finish he r m Upon completion of her m aster degree program in December 2011, she will be continuing her dental degre e in Philadelphia, which will be completed in May 2014. She plans to continue her education in a specialty program.



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Gene Symbol Gene Title Probe Set ID Entrez Gene Gender Enriched 2610029G23Rik RIKEN cDNA 2610029G23 gene 1417921_at 67683 F Sema4d sema domain, immunoglobulin domain (Ig), short cytoplasmic domain, (semaphorin) 4D 1420824_at 20354 F Rnps1 ribonucleic acid binding protein S1 1437359_at 19826 F Frem2 Fras1 related extracellular matrix protein 2 1457038_at 242022 F Gpc6 glypican 6 1441438_at 23888 F Fam168a Family with sequence similarity 168, member A 1444119_at 319604 F Timm22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1448518_at 56322 F ----1457480_at --F Eps15 epidermal growth factor receptor pathway substrate 15 1430152_at 13858 F ----1446278_at --F Kdm6a 4lysine (K)-specific demethylase 6A 1445198_at 22289 F Ank3 ankyrin 3, epithelial 1457288_at 11735 F Arr3 arrestin 3, retinal 1425232_x_at 170735 F Fancl Fanconi anemia, complementation group L 1432337_at 67030 F 9530006C21Rik RIKEN cDNA 9530006C21 gene 1441779_at 77393 F ----1438894_at --F D4Ertd58e DNA segment, Chr 4, ERATO Doi 58, expressed 1448089_at 52054 F Rhoa Ras homolog gene family, member A 1443768_at 11848 F D330022H12Rik RIKEN cDNA D330022H12 gene 1430251_at 77095 F A130022J21Rik RIKEN cDNA A130022J21 gene 1444764_at 320617 F ----1443675_at --F Tiam1 T-cell lymphoma invasion and metastasis 1 1444373_at 21844 F ----1446525_at --F Hmbox1 homeobox containing 1 1443020_at 219150 F ----1443247_at --F Igf1 insulin-like growth factor 1 1419519_at 16000 M Adamts5 /// LOC100048332 a disintegrin-like and metallopeptidase /// similar to a disintegrin-like and metalloprotease 1422561_at 100048332 /// 23794 M Slain1 SLAIN motif family, member 1 1424824_at 105439 M Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 1451716_at 16658 M Igf1 insulin-like growth factor 1 1434413_at 16000 M Igf1 insulin-like growth factor 1 1437401_at 16000 M Has2 hyaluronan synthase 2 1449169_at 15117 M Zdhhc14 zinc finger, DHHC domain containing 14 1438619_x_at 224454 M Tagln3 transgelin 3 1450683_at 56370 M Fam102b family with sequence similarity 102, member B 1455033_at 329739 M Smoc1 SPARC related modular calcium binding 1 1448321_at 64075 M Targets of the androgen receptor at E15.5.



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Gene Symbol Gene Title Probe Set ID Entrez Gene Gender Enriched Cluster Number* Cluster Order* Tmem109 transmembrane protein 109 1416032_at 68539 M 1 1 Rhbdl2 rhomboid, veinlet-like 2 (Drosophila) 1442819_at 230726 M 1 2 Fam3c family with sequence similarity 3, member C 1448904_at 27999 M 1 3 Stk17b serine/threonine kinase 17b (apoptosis-inducing) 1423452_at 98267 M 1 4 Slc39a8 solute carrier family 39 (metal ion transporter), member 8 1416832_at 67547 M 1 5 Mapre1 microtubule-associated protein, RP/EB family, member 1 1428819_at 13589 M 1 6 Myh9 myosin, heavy polypeptide 9, non-muscle 1420171_s_at 17886 M 1 7 Sash1 SAM and SH3 domain containing 1 1448005_at 70097 M 1 8 Col17a1 collagen, type XVII, alpha 1 1418799_a_at 12821 M 1 9 Reep3 receptor accessory protein 3 1424781_at 28193 M 1 10 Nipbl Nipped-B homolog (Drosophila) 1453576_at 71175 M 1 11 Dym dymeclin 1437141_x_at 69190 M 1 12 Arf3 ADP-ribosylation factor 3 1437331_a_at 11842 M 1 13 Ep400 E1A binding protein p400 1447349_s_at 75560 M 1 14 Cxxc5 CXXC finger 5 1448960_at 67393 M 1 15 Ptpn12 protein tyrosine phosphatase, non-receptor type 12 1450478_a_at 19248 M 1 16 Lgi2 leucine-rich repeat LGI family, member 2 1457040_at 246316 M 1 17 Pan3 PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae) 1428768_at 72587 M 1 18 Ypel5 yippee-like 5 (Drosophila) 1433593_at 383295 M 1 19 Wbscr27 Williams Beuren syndrome chromosome region 27 (human) 1418359_at 79565 M 1 20 Rgs3 regulator of G-protein signaling 3 1425296_a_at 50780 M 1 21 Rtkn rhotekin 1425601_a_at 20166 M 1 22 Chd1 chromodomain helicase DNA binding protein 1 1457473_at 12648 M 1 23 Swap70 SWA-70 protein 1434225_at 20947 M 1 24 AU040320 expressed sequence AU040320 1452150_at 100317 M 1 25 Iqsec1 IQ motif and Sec7 domain 1 1427145_at 232227 M 1 26 Tyrobp TYRO protein tyrosine kinase binding protein 1450792_at 22177 M 1 27 Vps11 vacuolar protein sorting 11 (yeast) 1428110_x_at 71732 M 1 28 Kctd14 potassium channel tetramerisation domain containing 14 1455452_x_at 233529 M 1 29 Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1417866_at 21927 M 1 30 Nudt18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 1435902_at 213484 M 1 31 Znf512b zinc finger protein 512B 1436184_at 269401 M 1 32 Btd biotinidase 1417987_at 26363 M 1 33 Fam82a2 family with sequence similarity 82, member A2 1428196_a_at 67809 M 1 34 Pygb brain glycogen phosphorylase 1433504_at 110078 M 1 35 Slc44a2 solute carrier family 44, member 2 1438559_x_at 68682 M 1 36 Cyb5r3 cytochrome b5 reductase 3 1422186_s_at 109754 M 1 37 Mib2 mindbomb homolog 2 (Drosophila) 1424862_s_at 76580 M 1 38 2310044G17Rik RIKEN cDNA 2310044G17 gene 1424915_s_at 217732 M 1 39 Ranbp2 RAN binding protein 2 1422621_at 19386 M 1 40 Pigh phosphatidylinositol glycan anchor biosynthesis, class H 1455860_at 110417 M 1 41 Stradb STE20-related kinase adaptor beta 1433544_at 227154 M 1 42 Gnb2 guanine nucleotide binding protein (G protein), beta 2 1450623_at 14693 M 1 43 Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 1436179_a_at 13002 M 1 44 Amotl1 angiomotin-like 1 1428785_at 75723 M 1 45 Naf1 nuclear assembly factor 1 homolog (S. cerevisiae) 1452192_at 234344 M 1 46 4933403F05Rik RIKEN cDNA 4933403F05 gene 1434979_at 108654 M 1 47 Plscr3 phospholipid scramblase 3 1449020_at 70310 M 1 48 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1449731_s_at 18035 M 1 49 Eif3a eukaryotic translation initiation factor 3, subunit A 1416660_at 13669 M 2 50 Gmeb1 glucocorticoid modulatory element binding protein 1 1456232_at 56809 M 2 51 Mfsd9 major facilitator superfamily domain containing 9 1460619_at 211798 M 2 52 Ctnnd1 catenin (cadherin associated protein), delta 1 1422450_at 12388 M 2 53 Fap fibroblast activation protein 1417552_at 14089 M 2 54 Cpeb2 cytoplasmic polyadenylation element binding protein 2 1434272_at 231207 M 2 55 Dmxl2 Dmx-like 2 1428749_at 235380 M 2 56 Pak3 p21 protein (Cdc42/Rac)-activated kinase 3 1435486_at 18481 M 2 57 Flt1 FMS-like tyrosine kinase 1 1451756_at 14254 M 2 58 Slco5a1 solute carrier organic anion transporter family, member 5A1 1440874_at 240726 M 2 59 Acvr1 activin A receptor, type 1 1416786_at 11477 M 2 60 Map3k7ip3 mitogen-activated protein kinase kinase kinase 7 interacting protein 3 1428762_at 66724 M 2 61 Ubr3 ubiquitin protein ligase E3 component n-recognin 3 1429107_at 68795 M 2 62 Kif13a kinesin family member 13A 1451890_at 16553 M 2 63 Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) 1420563_at 53623 M 2 64 Baiap2l1 BAI1-associated protein 2-like 1 1424951_at 66898 M 2 65 BC059842 cDNA sequence BC059842 1440819_s_at 230676 M 2 66 Gm129 predicted gene 129 1435188_at 229599 M 2 67 Fbxo6 F-box protein 6 1417501_at 50762 M 2 68 Msi2 Musashi homolog 2 (Drosophila) 1435521_at 76626 M 2 69 Bche butyrylcholinesterase 1436098_at 12038 M 2 70 ----1430245_at --M 2 71 Ltbp4 latent transforming growth factor beta binding protein 4 1436665_a_at 108075 M 2 72 Egr2 early growth response 2 1427683_at 13654 M 2 73 Nipal1 NIPA-like domain containing 1 1456321_at 70701 M 2 74 Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 1435461_at 99470 M 2 75 Egfr epidermal growth factor receptor 1435888_at 13649 M 2 76 Inadl InaD-like (Drosophila) 1418983_at 12695 M 2 77 Foxc1 forkhead box C1 1419486_at 17300 M 2 78 Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase 5 1425702_a_at 83965 M 2 79 Cds1 CDP-diacylglycerol synthase 1 1456114_at 74596 M 2 80 Serinc5 serine incorporator 5 1433571_at 218442 M 2 81 ----1445758_at --M 2 82 Vps37a vacuolar protein sorting 37A (yeast) 1419177_at 52348 M 2 83 N4bp1 NEDD4 binding protein 1 1455606_at 80750 M 2 84 Samd8 sterile alpha motif domain containing 8 1434402_at 67630 M 2 85 Eif2c1 eukaryotic translation initiation factor 2C, 1 1434331_at 236511 M 2 86 Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 1437149_at 21366 M 2 87 Myo1c myosin IC 1419648_at 17913 M 2 88 Slit3 Slit homolog 3 (Drosophila) 1427086_at 20564 M 2 89 BC023744 cDNA sequence BC023744 1436591_at 231668 M 2 90 Coro1a coronin, actin binding protein 1A 1416246_a_at 12721 F 3 91 Ddx28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 1428702_at 71986 F 3 92 Dimorphically expressed genes in the female versus male comparison at E13.5

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Pla2g12a phospholipase A2, group XIIA 1452026_a_at 66350 F 3 93 Ttc26 tetratricopeptide repeat domain 26 1435401_at 264134 F 3 94 Mrps25 mitochondrial ribosomal protein S25 1418716_at 64658 F 3 95 Ncbp2 nuclear cap binding protein subunit 2 1423045_at 68092 F 3 96 Prpf3 PRP3 pre-mRNA processing factor 3 homolog (yeast) 1424314_at 70767 F 3 97 Tusc4 tumor suppressor candidate 4 1417046_at 56032 F 3 98 Eif1b eukaryotic translation initiation factor 1B 1428272_at 68969 F 3 99 Gm13880 /// Trappc6b predicted gene 13880 /// trafficking protein particle complex 6B 1428177_at 433458 /// 78232 F 3 100 Bag2 BCL2-associated athanogene 2 1423948_at 213539 F 3 101 Orc2l origin recognition complex, subunit 2-like (S. cerevisiae) 1418226_at 18393 F 3 102 Taf9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1422778_at 108143 F 3 103 Msra methionine sulfoxide reductase A 1448856_a_at 110265 F 3 104 Hmbs hydroxymethylbilane synthase 1426475_at 15288 F 3 105 Dnajc4 DnaJ (Hsp40) homolog, subfamily C, member 4 1417934_at 57431 F 3 106 Arpc4 actin related protein 2/3 complex, subunit 4 1423588_at 68089 F 3 107 Arf1 ADP-ribosylation factor 1 1426390_a_at 11840 F 3 108 Arglu1 arginine and glutamate rich 1 1433597_at 234023 F 3 109 Racgap1 Rac GTPase-activating protein 1 1451358_a_at 26934 F 3 110 Spg21 spastic paraplegia 21 homolog (human) 1451036_at 27965 F 3 111 Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 1452046_a_at 19047 F 3 112 Coil coilin 1416692_at 12812 F 3 113 Trim37 tripartite motif-containing 37 1436394_at 68729 F 3 114 Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 1423826_at 100608 F 3 115 Gle1 GLE1 RNA export mediator (yeast) 1426344_at 74412 F 3 116 Senp2 SUMO/sentrin specific peptidase 2 1451717_s_at 75826 F 3 117 2610306M01Rik RIKEN cDNA 2610306M01 gene 1452988_at 67170 F 3 118 4930453N24Rik RIKEN cDNA 4930453N24 gene 1449718_s_at 67609 F 3 119 Stx18 syntaxin 18 1453819_x_at 71116 F 3 120 Tspan13 tetraspanin 13 1460239_at 66109 F 3 121 Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 1423109_s_at 57279 F 3 122 Homer3 homer homolog 3 (Drosophila) 1424859_at 26558 F 3 123 Gm5871 /// Smndc1 predicted gene 5871 /// survival motor neuron domain containing 1 1443396_at 545792 /// 76479 F 3 124 Smpd2 sphingomyelin phosphodiesterase 2, neutral 1416999_at 20598 F 3 125 5530601H04Rik RIKEN cDNA 5530601H04 gene 1452750_at 71445 F 3 126 Gla galactosidase, alpha 1418248_at 11605 F 3 127 Lrrc57 leucine rich repeat containing 57 1428312_at 66606 F 3 128 Isl2 insulin related protein 2 (islet 2) 1418676_at 104360 F 3 129 Dusp11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 1452594_at 72102 F 3 130 B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 1420993_at 108105 F 3 131 Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked 1423744_x_at 26905 F 3 132 Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked 1451090_a_at 26905 F 3 133 2610029G23Rik RIKEN cDNA 2610029G23 gene 1417921_at 67683 F 3 134 Mrps9 mitochondrial ribosomal protein S9 1435843_x_at 69527 F 3 135 Eif2s3x /// LOC100048746 eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked 1421895_at 100048746 /// 26905 F 3 136 Senp2 SUMO/sentrin specific peptidase 2 1425465_a_at 75826 F 3 137 Cd99l2 CD99 antigen-like 2 1456746_a_at 171486 F 3 138 Ccdc88c coiled-coil domain containing 88C 1427138_at 68339 F 3 139 5730422E09Rik RIKEN cDNA 5730422E09 gene 1444601_at 433966 F 3 140 ----1445350_at --F 3 141 Tigd5 tigger transposable element derived 5 1460743_at 105734 F 3 142 Dab2 disabled homolog 2 (Drosophila) 1430604_a_at 13132 F 3 143 ----1457480_at --F 3 144 Zfp719 zinc finger protein 719 1443985_at 210105 F 3 145 Adarb2 adenosine deaminase, RNA-specific, B2 1458112_at 94191 F 3 146 Tubb2a-ps2 tubulin, beta 2a, pseudogene 2 1449683_x_at 627110 F 3 147 Apod apolipoprotein D 1416371_at 11815 F 4 148 Zbtb16 zinc finger and BTB domain containing 16 1419874_x_at 235320 F 4 149 Vwf Von Willebrand factor homolog 1435386_at 22371 F 4 150 Mapre3 microtubule-associated protein, RP/EB family, member 3 1427079_at 100732 F 4 151 Hal histidine ammonia lyase 1418645_at 15109 F 4 152 Apba1 amyloid beta (A4) precursor protein binding, family A, member 1 1455369_at 319924 F 4 153 1110064A23Rik RIKEN cDNA 1110064A23 gene 1439543_at 68893 F 4 154 Camk2d calcium/calmodulin-dependent protein kinase II, delta 1460630_at 108058 F 4 155 Pkp3 plakophilin 3 1418832_at 56460 F 4 156 Clec4a3 C-type lectin domain family 4, member a3 1429954_at 73149 F 4 157 Mmrn2 multimerin 2 1439518_at 105450 F 4 158 Tshz2 teashirt zinc finger family member 2 1459250_at 228911 F 4 159 Tmem202 Transmembrane protein 202 1443186_at 73893 F 4 160 ----1459123_at --F 4 161 Epb4.1l1 erythrocyte protein band 4.1-like 1 1421090_at 13821 F 4 162 Tpsab1 tryptase alpha/beta 1 1426175_a_at 17230 F 4 163 Plxnc1 plexin C1 1450905_at 54712 F 4 164 Daam1 dishevelled associated activator of morphogenesis 1 1458662_at 208846 F 4 165 Prei4 preimplantation protein 4 1437953_at 74182 F 4 166 Pcdhb11 Protocadherin beta 11 1456710_at 93882 F 4 167 Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 1422671_s_at 72560 F 4 168 Cytip cytohesin 1 interacting protein 1435697_a_at 227929 F 4 169 Wdr61 WD repeat domain 61 1454954_at 66317 F 4 170 Optn optineurin 1435679_at 71648 F 4 171 Depdc6 DEP domain containing 6 1451348_at 97998 F 4 172 Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 1448789_at 56847 F 4 173 Vsig8 V-set and immunoglobulin domain containing 8 1436671_at 240916 F 4 174 4930518F22Rik RIKEN cDNA 4930518F22 gene 1458063_at 71655 F 4 175 Pip5k1b phosphatidylinositol-4-phosphate 5-kinase, type 1 beta 1450389_s_at 18719 F 4 176 Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 1427019_at 19283 F 4 177 1500001A10Rik RIKEN cDNA 1500001A10 gene 1435062_at 68955 F 4 178 Gria4 Glutamate receptor, ionotropic, AMPA4 (alpha 4) 1436772_at 14802 F 4 179 Nfic nuclear factor I/C 1427665_a_at 18029 F 4 180 Sfmbt2 Scm-like with four mbt domains 2 1434353_at 353282 F 4 181 P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 1419853_a_at 18439 F 5 182 Lipm lipase, family member M 1430550_at 78753 F 5 183 ----1441854_at --F 5 184 Rims2 regulating synaptic membrane exocytosis 2 1422809_at 116838 F 5 185 B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 1455234_at 26877 F 5 186

PAGE 3

Bend6 BEN domain containing 6 1434590_at 320705 F 5 187 Lipk lipase, family member K 1443914_at 240633 F 5 188 Arrdc2 arrestin domain containing 2 1428352_at 70807 F 5 189 Uty Ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome 1457582_at 22290 F 6 190 Thbs3 thrombospondin 3 1416623_at 21827 F 7 191 Glt25d2 glycosyltransferase 25 domain containing 2 1437930_at 269132 F 7 192 ----1442157_at --F 7 193 ----1439011_at --F 7 194 Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 1417416_at 16485 F 7 195 Slc4a3 solute carrier family 4 (anion exchanger), member 3 1418485_at 20536 F 7 196 Tsc22d2 TSC22 domain family, member 2 1453012_at 72033 F 7 197 Dhx38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 1453751_at 64340 F 7 198 Aff1 AF4/FMR2 family, member 1 1418135_at 17355 F 7 199 Ephx1 epoxide hydrolase 1, microsomal 1422438_at 13849 F 7 200 Rgs5 regulator of G-protein signaling 5 1420940_x_at 19737 F 7 201 Arhgap20 Rho GTPase activating protein 20 1427522_at 244867 F 7 202 Hs1bp3 HCLS1 binding protein 3 1421994_a_at 58240 F 7 203 Nqo2 NAD(P)H dehydrogenase, quinone 2 1436189_at 18105 F 7 204 Myl7 myosin, light polypeptide 7, regulatory 1449071_at 17898 F 7 205 Fam19a5 family with sequence similarity 19, member A5 1419490_at 106014 F 7 206 Grin3a glutamate receptor ionotropic, NMDA3A 1438866_at 242443 F 7 207 Mboat1 membrane bound O-acyltransferase domain containing 1 1435323_a_at 218121 F 7 208 Pja2 praja 2, RING-H2 motif containing 1427148_at 224938 F 7 209 Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1435078_at 77097 F 7 210 1110059G02Rik RIKEN cDNA 1110059G02 gene 1436204_at 68786 F 7 211 C1qb complement component 1, q subcomponent, beta polypeptide 1437726_x_at 12260 F 7 212 Endod1 endonuclease domain containing 1 1426540_at 71946 F 7 213 Stim2 stromal interaction molecule 2 1441024_at 116873 F 7 214 Ppp1r3g protein phosphatase 1, regulatory (inhibitor) subunit 3G 1428923_at 76487 F 7 215 2900054C01Rik RIKEN cDNA 2900054C01 gene 1429625_at 73049 F 7 216 Msrb3 methionine sulfoxide reductase B3 1439151_at 320183 F 7 217 0710007G10Rik /// Tmem175 RIKEN cDNA 0710007G10 gene /// transmembrane protein 175 1435109_at 68409 /// 72392 F 7 218 Myo19 myosin XIX 1451183_at 66196 F 7 219 Actr1b ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 1452057_at 226977 F 7 220 ----1420178_at --F 8 221 Zfp182 zinc finger protein 182 1446820_at 319535 F 8 222 Krtap17-1 keratin associated protein 17-1 1453523_at 77914 F 8 223 Tmem168 transmembrane protein 168 1432311_at 101118 F 8 224 Ccl25 chemokine (C-C motif) ligand 25 1458277_at 20300 F 8 225 Ap2a2 adaptor protein complex AP-2, alpha 2 subunit 1432007_s_at 11772 F 8 226 Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 1420968_at 66830 F 8 227 Gm10072 /// Gm16382 /// Gm5437 /// Gm6635 /// Gm6670 /// Gm9154 /// Gm9228 // predicted gene 10072 /// ribosomal protein L31 pseudogene 1441304_at 100043192 /// 114641 /// 432681 /// 625917 /// 626367 /// 638399 /// 66840 F 8 228 Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 1455740_at 15382 F 8 229 ----1421481_at --F 8 230 D530017H19Rik RIKEN cDNA D530017H19 gene 1446774_at 78713 F 8 231 ----1445874_at --F 8 232 Ttk Ttk protein kinase 1442594_at 22137 F 8 233 Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 1447882_x_at 71990 F 8 234 Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 1428205_x_at 14401 F 8 235 Cbx1 chromobox homolog 1 (Drosophila HP1 beta) 1450797_a_at 12412 F 8 236 Oaz3 ornithine decarboxylase antizyme 3 1437010_a_at 53814 F 8 237 ----1441119_at --F 8 238 ----1446480_at --F 8 239 Zfp664 zinc finger protein 664 1437047_at 269704 F 8 240 Dcun1d5 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) 1444582_at 76863 F 8 241 ----1446720_at --F 8 242 Kcns3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 1457799_at 238076 F 8 243 Msr1 macrophage scavenger receptor 1 1422062_at 20288 F 9 244 Nhsl1 NHS-like 1 1430810_at 215819 F 9 245 Csn1s2a casein alpha s2-like A 1455579_at 12993 F 9 246 ----1440433_at --F 9 247 F830028O17Rik RIKEN cDNA F830028O17 gene 1436457_at 320071 F 9 248 ----1457971_at --F 9 249 2310010M20Rik RIKEN cDNA 2310010M20 gene 1432107_at 69576 F 9 250 Gm10001 predicted gene 10001 1440534_at 791296 F 9 251 ----1447094_at --F 9 252 Gm2590 predicted gene 2590 1440573_at 100040086 F 9 253 A730041O05Rik RIKEN cDNA A730041O05 gene 1459012_at 320330 F 9 254 B230343J05Rik RIKEN cDNA B230343J05 gene 1436432_at 320320 F 9 255 Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 1443536_at 26570 F 9 256 Pilra paired immunoglobin-like type 2 receptor alpha 1427327_at 231805 F 9 257 ----1431996_at --F 9 258 Kif2a kinesin family member 2A 1432072_at 16563 F 9 259 Trav17 T cell receptor alpha variable 17 1443140_at 627777 F 9 260 Trim7 tripartite motif-containing 7 1439352_at 94089 F 9 261 Slc20a1 solute carrier family 20, member 1 1446441_at 20515 F 9 262 B230339M05Rik RIKEN cDNA B230339M05 gene 1457488_at 228850 F 9 263 Sync syncoilin 1432349_a_at 68828 F 9 264 Vps18 vacuolar protein sorting 18 (yeast) 1442112_at 228545 F 9 265 ----1445549_at --F 9 266 ----1442404_at --F 9 267 Ajap1 adherens junction associated protein 1 1438662_at 230959 F 9 268 Xist inactive X specific transcripts 1427262_at 213742 F 10 269 Xist inactive X specific transcripts 1436936_s_at 213742 F 10 270 Xist inactive X specific transcripts 1427263_at 213742 F 10 271 Cluster Number and Cluster Order corresponds to Figure 1b, female versus male at E13.5 dendrogram.





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Gene Symbol Gene Title Probe Set ID Entrez Gene Gender enriched Cluster Number* Cluster Order* Cox4i2 cytochrome c oxidase subunit IV isoform 2 1421373_at 84682 F 1 1 Eif2s3x /// LOC100048746 eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked /// similar to translation initiation factor eIF-2 gamma subunit 1421895_at 100048746 /// 26905 F 1 2 Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked 1423744_x_at 26905 F 1 3 Zscan12 zinc finger and SCAN domain containing 12 1451281_at 22758 F 1 4 Abcf3 ATP-binding cassette, sub-family F (GCN20), member 3 1426747_at 27406 F 1 5 Kdm6a 4lysine (K)-specific demethylase 6A 1427672_a_at 22289 F 1 6 Ssbp2 single-stranded DNA binding protein 2 1429951_at 66970 F 2 7 4931431B13Rik RIKEN cDNA 4931431B13 gene 1430416_at 70973 F 2 8 Tmem213 transmembrane protein 213 1453480_at 77522 F 2 9 Vamp3 vesicle-associated membrane protein 3 1433693_x_at 22319 F 2 10 Fras1 Fraser syndrome 1 homolog (human) 1440765_at 231470 F 2 11 Ncapd3 non-SMC condensin II complex, subunit D3 1430782_at 78658 F 3 12 Tsc22d1 TSC22 domain family, member 1 1447360_at 21807 F 3 13 4930518F22Rik RIKEN cDNA 4930518F22 gene 1458063_at 71655 F 3 14 4933401J01Rik RIKEN cDNA 4933401J01 gene 1454564_at 71042 F 3 15 ----1457971_at --F 3 16 ----1446713_at --F 3 17 ----1439216_at --F 4 18 ----1444326_at --F 4 19 A730041O05Rik RIKEN cDNA A730041O05 gene 1459012_at 320330 F 4 20 Xist inactive X specific transcripts 1427262_at 213742 F 5 21 Xist inactive X specific transcripts 1436936_s_at 213742 F 5 22 Ddx3y DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked 1426439_at 26900 M 6 23 Uty ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome 1426598_at 22290 M 7 24 Ddx3y DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked 1452077_at 26900 M 8 25 B830012L14Rik RIKEN cDNA B830012L14 gene 1439311_at 320085 M 9 26 ----1445093_at --M 9 27 Gca grancalcin 1451451_at 227960 M 9 28 ----1443731_at --M 10 29 ----1445020_at --M 10 30 ----1458521_at --M 10 31 Dimorphically expressed genes in the female versus male comparison at E15.5 Cluster Number and Cluster Order corresponds to Figure 2b, female versus male at E15.5





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Differentially expressed genes in the male at E13.5 versus male at E15.5 comparison Gene Symbol Gene Title Probe Set ID Chromosomal Location Entrez Gene Stage Enriched Cluster Number* Cluster Order* Ssr3 signal sequence receptor, gamma 1415700_a_at chr3 E1 67437 15.5 1 1 Styx serine/threonine/tyrosine interaction protein 1429710_at chr14 C1 56291 15.5 1 2 Fkbp7 FK506 binding protein 7 1416803_at chr2 C3|2 60.5 cM 14231 15.5 1 3 Asb7 ankyrin repeat and SOCS box-containing 7 1435010_at chr7 C 117589 15.5 1 4 Lrp10 low-density lipoprotein receptor-related protein 10 1416836_at chr14 C2-C3 65107 15.5 1 5 Rab9 RAB9, member RAS oncogene family 1448391_at chrX F5 56382 15.5 1 6 Sigmar1 sigma non-opioid intracellular receptor 1 1451956_a_at chr4 A5-B2 18391 15.5 1 7 Herpud2 HERPUD family member 2 1415982_at chr9 A4 80517 15.5 1 8 Rag1ap1 recombination activating gene 1 activating protein 1 1448948_at chr3 F1|3 44.3 cM 19729 15.5 1 9 Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 1450010_at chr2 E1 56348 15.5 1 10 Mknk2 MAP kinase-interacting serine/threonine kinase 2 1418300_a_at chr10 C1 17347 15.5 1 11 Sptlc1 serine palmitoyltransferase, long chain base subunit 1 1422690_at chr13 B1 268656 15.5 1 12 Setd3 SET domain containing 3 1451748_a_at chr12 F1|12 53.0 cM 52690 15.5 1 13 Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 1428645_at chr3 F2.3|3 48.8 cM 14679 15.5 1 14 Lztfl1 leucine zipper transcription factor-like 1 1417170_at chr9 F|9 71.1 cM 93730 15.5 1 15 Fbxo3 F-box protein 3 1423490_at chr2 E2 57443 15.5 1 16 Prei4 preimplantation protein 4 1429144_at chr2 F3|2 74182 15.5 1 17 Rnf167 ring finger protein 167 1430527_a_at chr11 B4 70510 15.5 1 18 Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 1423109_s_at chr9 F2 57279 15.5 1 19 Rab7l1 RAB7, member RAS oncogene family-like 1 1451362_at chr1 E4 226422 15.5 1 20 Tatdn1 TatD DNase domain containing 1 1448033_at chr15 D1 69694 15.5 1 21 Azi2 5-azacytidine induced gene 2 1431822_a_at chr9 F3 27215 15.5 1 22 Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H 1415826_at chr1 A1 108664 15.5 1 23 Tm9sf2 transmembrane 9 superfamily member 2 1455875_x_at chr14 E5|14 67.0 cM 68059 15.5 1 24 Acbd3 acyl-Coenzyme A binding domain containing 3 1452137_at chr1 H4|1 98.7 cM 170760 15.5 1 25 Vkorc1 vitamin K epoxide reductase complex, subunit 1 1452770_at chr7 F3|7 61.0 cM 27973 15.5 1 26 Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) 1417649_at chr7 F5|7 69.49 cM 12577 15.5 1 27 Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1423126_at chr9 E3.3|9 51.0 cM 11933 15.5 1 28 Ckap4 cytoskeleton-associated protein 4 1426754_x_at chr10 C1 216197 15.5 1 29 Ero1l ERO1-like (S. cerevisiae) 1419029_at chr14 C-D 50527 15.5 1 30 Mapk1 mitogen-activated protein kinase 1 1426585_s_at chr16 A3|16 9.82 cM 26413 15.5 1 31 Gpam glycerol-3-phosphate acyltransferase, mitochondrial 1419499_at chr19 D2|19 52.0 cM 14732 15.5 1 32 Rab11a RAB11a, member RAS oncogene family 1449256_a_at chr9 C 53869 15.5 1 33 6330409N04Rik RIKEN cDNA 6330409N04 gene 1429723_at chr14 D1 66674 15.5 1 34 Acadm acyl-Coenzyme A dehydrogenase, medium chain 1415984_at chr3 H3|3 73.6 cM 11364 15.5 1 35 Nek7 NIMA (never in mitosis gene a)-related expressed kinase 7 1416816_at chr1 E4|1 73.0 cM 59125 15.5 1 36 BC013529 cDNA sequence BC013529 1424026_s_at chr10 A1 215751 15.5 1 37 Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 1449372_at chr14 E4 100037258 15.5 1 38 Lxn latexin 1416503_at chr3 E1|3 31.6 cM 17035 15.5 1 39 Gas6 growth arrest specific 6 1417399_at chr8 A1.1|8 5.0 cM 14456 15.5 1 40 Ppp2r5a protein phosphatase 2, regulatory subunit B (B56), alpha isoform 1423911_at chr1 H6 226849 15.5 1 41 Chmp2b chromatin modifying protein 2B 1428252_at chr16 C1.3 68942 15.5 1 42 Tm9sf3 transmembrane 9 superfamily member 3 1460186_at chr19 C3 107358 15.5 1 43 Stx4a syntaxin 4A (placental) 1451573_a_at chr7 F4 20909 15.5 1 44 Rab1 RAB1, member RAS oncogene family 1416082_at chr11 A3.1|11 10.9 cM 19324 15.5 1 45 Rab18 RAB18, member RAS oncogene family 1420900_a_at chr18 A1|18 7.5 cM 19330 15.5 1 46 Capza2 capping protein (actin filament) muscle Z-line, alpha 2 1423057_at chr6 A2|6 3.05 cM 12343 15.5 1 47 Cntd1 Cyclin N-terminal domain containing 1 1439405_x_at chr11 D 68107 15.5 1 48 1110003E01Rik RIKEN cDNA 1110003E01 gene 1416768_at chr5 C3.1 68552 15.5 1 49 Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 1428190_at chr16 B1|16 10.65 cM 13358 15.5 1 50 9530068E07Rik RIKEN cDNA 9530068E07 gene 1427108_at chr11 B1.3 213673 15.5 1 51 Tmed9 transmembrane emp24 protein transport domain containing 9 1448268_at chr13 B2 67511 15.5 1 52 Tubb2c tubulin, beta 2C 1423642_at chr2 A3 227613 15.5 1 53 Cttn cortactin 1423917_a_at chr7 F5 13043 15.5 1 54 Sec22b SEC22 vesicle trafficking protein homolog B (S. cerevisiae) 1449063_at chr3 F2.2 20333 15.5 1 55 Arcn1 archain 1 1451089_a_at chr9 A5.2 213827 15.5 1 56 Calu calumenin 1415870_at chr6 A3.3 12321 15.5 1 57 Tmem30a transmembrane protein 30A 1448339_at chr9 E1 69981 15.5 1 58 Scamp2 secretory carrier membrane protein 2 1448404_at chr9 B 24044 15.5 1 59 Bmp2k BMP2 inducible kinase 1437419_at chr5 E3 140780 15.5 1 60 Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) 1416840_at chrX A1.2 68041 15.5 1 61 Rbms1 RNA binding motif, single stranded interacting protein 1 1434005_at chr2 C3 56878 15.5 1 62 Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1448684_at chr16 B2 66849 15.5 1 63 Canx calnexin 1428935_at chr11 B1.3|11 30.0 cM 12330 15.5 1 64 Cd81 CD81 antigen 1416330_at chr7 F5|7 69.3 cM 12520 15.5 1 65 Chsy1 /// LOC100047167 chondroitin sulfate synthase 1 /// similar to mKIAA0990 protein 1434316_at chr7 C 100047167 /// 269941 15.5 1 66 Anxa3 annexin A3 1460330_at chr5 E3|5 54.0 cM 11745 15.5 1 67 Jak2 Janus kinase 2 1421066_at chr19 C1|19 24.0 cM 16452 15.5 1 68 Psat1 phosphoserine aminotransferase 1 1451064_a_at chr19 A|19 32.5 cM 107272 15.5 1 69 Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 1422508_at chr16 B4 11964 15.5 1 70 Mycbp2 MYC binding protein 2 1434937_at chr14 E2.3|14 54.58 cM 105689 15.5 1 71 Fkbp9 FK506 binding protein 9 1437687_x_at chr6 B3|6 28.0 cM 27055 15.5 1 72 Snx4 sorting nexin 4 1460182_at chr16 B3 69150 15.5 1 73 Abhd5 abhydrolase domain containing 5 1417566_at chr9 F4 67469 15.5 1 74 Gphn gephyrin 1426462_at chr12 D2 268566 15.5 1 75 Clint1 clathrin interactor 1 1452152_at chr11 B1.1 216705 15.5 1 76 Gulp1 GULP, engulfment adaptor PTB domain containing 1 1434423_at chr1 C1 70676 15.5 1 77 Fkbp9 FK506 binding protein 9 1423677_at chr6 B3|6 28.0 cM 27055 15.5 1 78 Myl9 myosin, light polypeptide 9, regulatory 1452670_at chr2 H1 98932 15.5 1 79 Klf6 Kruppel-like factor 6 1433508_at chr13 A1 23849 15.5 1 80 Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 1437688_x_at chrX A1.1 70495 15.5 1 81 5033414K04Rik RIKEN cDNA 5033414K04 gene 1436999_at chr1 C5 98496 15.5 1 82 Serinc3 serine incorporator 3 1455550_x_at chr2 H3 26943 15.5 1 83 Snap23 synaptosomal-associated protein 23 1420896_at chr2 E5|2 61.8 cM 20619 15.5 1 84 Pppde1 PPPDE peptidase domain containing 1 1451621_at chr1 H3 78825 15.5 1 85 Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 1448104_at chr12 D1 104776 15.5 1 86

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Yipf6 Yip1 domain family, member 6 1455111_at chrX C2 77929 15.5 1 87 Nipal1 NIPA-like domain containing 1 1456321_at chr5 C3.2 70701 15.5 1 88 Ckb creatine kinase, brain 1455106_a_at chr12 F1|12 55.0 cM 12709 15.5 1 89 2610507B11Rik RIKEN cDNA 2610507B11 gene 1455905_at chr11 B5|11 44.93 cM 72503 15.5 1 90 Ctla2a /// Ctla2b cytotoxic T lymphocyte-associated protein 2 alpha /// cytotoxic T lymphocyte-associated protein 2 beta 1416811_s_at chr12 C1|13 /// chr13 B2|13 36.0 cM 13024 /// 13025 15.5 1 91 Stxbp6 syntaxin binding protein 6 (amisyn) 1425749_at chr12 B3 217517 15.5 1 92 Fyn Fyn proto-oncogene 1448765_at chr10 B1|10 25.0 cM 14360 15.5 1 93 Pggt1b protein geranylgeranyltransferase type I, beta subunit 1438229_at chr18 C 225467 15.5 1 94 Camta2 calmodulin binding transcription activator 2 1426901_s_at chr11 B3|11 42.0 cM 216874 15.5 1 95 Sfrs17b splicing factor, arginine/serine-rich 17b 1457265_at chrX A3.3 338351 15.5 1 96 Tmem106b transmembrane protein 106B 1452290_at chr6 A2 71900 15.5 1 97 Insig2 insulin induced gene 2 1417982_at chr1 E2 72999 15.5 1 98 Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 1423621_a_at chr3 E1-E3 11416 15.5 1 99 ----1437073_x_at ----15.5 1 100 LOC100046186 /// Ramp3 similar to receptor activity modifying protein 3 /// receptor (calcitonin) activity modifying protein 3 1420401_a_at chr11 A1|11 2.1 cM 100046186 /// 56089 15.5 1 101 Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 1449893_a_at chr6 D2|6 39.0 cM 16206 15.5 1 102 Zfp185 zinc finger protein 185 1420944_at chrX A7.3|X 28.95 cM 22673 15.5 1 103 Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal 1448621_a_at chr7 E3|7 51.0 cM 20597 15.5 1 104 Pros1 protein S (alpha) 1426246_at chr16 C1.3 19128 15.5 1 105 Fam126b family with sequence similarity 126, member B 1438221_at chr1 C1.3 213056 15.5 1 106 Ptgr1 prostaglandin reductase 1 1417777_at chr4 C1 67103 15.5 1 107 Fam102b family with sequence similarity 102, member B 1455033_at chr3 F3 329739 15.5 1 108 Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 1457248_x_at chr1 H3 15490 15.5 1 109 Foxc1 forkhead box C1 1419486_at chr13 A3.2|13 20.0 cM 17300 15.5 1 110 Unc84b unc-84 homolog B (C. elegans) 1433832_at chr15 E1 223697 15.5 1 111 Agtr2 angiotensin II receptor, type 2 1415832_at chrX A2|X 12.5 cM 11609 15.5 2 112 Ogn osteoglycin 1419663_at chr13 A5 18295 15.5 2 113 Ebf1 early B-cell factor 1 1416301_a_at chr11 B1.1|11 20.0 cM 13591 15.5 2 114 Tmem117 transmembrane protein 117 1433615_at chr15 E3 320709 15.5 2 115 Srgn serglycin 1417426_at chr10 B4 19073 15.5 2 116 Trim7 tripartite motif-containing 7 1439352_at chr11 B1.2 94089 15.5 2 117 Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 1418601_at chr19 B|19 20.0 cM 26358 15.5 2 118 Bglap-rs1 /// Bglap1 /// Bglap2 bone gamma-carboxyglutamate protein, related sequence 1 1449880_s_at chr3 F1|3 42.6 cM 12095 /// 12096 /// 12097 15.5 2 119 Glrx glutaredoxin 1416592_at chr13 C1|13 44.0 cM 93692 15.5 2 120 Tuba4a tubulin, alpha 4A 1417373_a_at chr1 C3 22145 15.5 2 121 Pdzk1ip1 PDZK1 interacting protein 1 1417689_a_at chr4 D1 67182 15.5 2 122 Npl N-acetylneuraminate pyruvate lyase 1424265_at chr1 G2 74091 15.5 2 123 Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 1451716_at chr2 H2|2 91.0 cM 16658 15.5 2 124 CU041261.1 /// LOC100189605 /// Mup1 /// Mup10 /// Mup12 /// Mup2 /// Mup7 // major urinary protein LOC100048885 1420465_s_at chr4 B3 /// chr4 B3|4 /// chr4 B3|4 27.8 cM 100039008 /// 100039054 /// 100041658 /// 100041687 /// 100048885 /// 1001 15.5 2 125 Hopx HOP homeobox 1428662_a_at chr5 C3.3 74318 15.5 2 126 Glrx glutaredoxin 1416593_at chr13 C1|13 44.0 cM 93692 15.5 2 127 Car13 carbonic anhydrase 13 1421307_at chr3 A2 71934 15.5 2 128 Sdpr serum deprivation response 1416778_at chr1 C1.1 20324 15.5 2 129 Nt5e 5' nucleotidase, ecto 1428547_at chr9 E3.2 23959 15.5 2 130 Rgs5 regulator of G-protein signaling 5 1417466_at chr1 H2|1 86.5 cM 19737 15.5 2 131 Kctd12 potassium channel tetramerisation domain containing 12 1434881_s_at chr14 E2.3 239217 15.5 2 132 Igf1 insulin-like growth factor 1 1434413_at chr10 C1|10 48.0 cM 16000 15.5 2 133 Hopx HOP homeobox 1451776_s_at chr5 C3.3 74318 15.5 2 134 Akap12 A kinase (PRKA) anchor protein (gravin) 12 1419706_a_at chr10 A1 83397 15.5 2 135 Gng4 guanine nucleotide binding protein (G protein), gamma 4 1447669_s_at chr13 A1|13 7.0 cM 14706 15.5 2 136 Sdpr serum deprivation response 1443832_s_at chr1 C1.1 20324 15.5 2 137 Acsl1 acyl-CoA synthetase long-chain family member 1 1423883_at chr8 B2 14081 15.5 2 138 Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 1427183_at chr11 A4 216616 15.5 2 139 2610528A11Rik RIKEN cDNA 2610528A11 gene 1435639_at chr14 B 70045 15.5 2 140 Psapl1 prosaposin-like 1 1429457_at chr5 B3 76943 15.5 2 141 Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 1443536_at chr3 D|3 16.4 cM 26570 15.5 2 142 Ifi27l1 interferon, alpha-inducible protein 27 like 1 1454757_s_at chr12 E|12 51.0 cM 52668 15.5 2 143 Cpa3 carboxypeptidase A3, mast cell 1448730_at chr3 A2|3 13.2 cM 12873 15.5 2 144 Adh1 alcohol dehydrogenase 1 (class I) 1416225_at chr3 G3|3 71.2 cM 11522 15.5 3 145 Pmp22 peripheral myelin protein 22 1417133_at chr11 B3|11 34.45 cM 18858 15.5 3 146 Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform 1424453_at chr16 B3|16 22.85 cM 13026 15.5 3 147 Slc39a2 solute carrier family 39 (zinc transporter), member 2 1443163_at chr14 C2 214922 15.5 3 148 Glt8d2 glycosyltransferase 8 domain containing 2 1429403_x_at chr10 C1 74782 15.5 3 149 Adamts5 /// LOC100048332 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) 1456404_at chr16 C3.3|16 62.0 cM 100048332 /// 23794 15.5 3 150 Lst1 leukocyte specific transcript 1 1425548_a_at chr17 B1|17 19.06 cM 16988 15.5 3 151 Sgms1 sphingomyelin synthase 1 1426576_at chr19 C1 208449 15.5 3 152 Igf1 insulin-like growth factor 1 1437401_at chr10 C1|10 48.0 cM 16000 15.5 3 153 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1451152_a_at chr1 H2.2|1 86.8 cM 11931 15.5 3 154 Hs3st1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 1423450_a_at chr5 B3|5 22.0 cM 15476 15.5 3 155 Axl AXL receptor tyrosine kinase 1423586_at chr7 A3-B1|7 6.0 cM 26362 15.5 3 156 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 1424638_at chr17 A3.3|17 15.23 cM 12575 15.5 3 157 Spag9 sperm associated antigen 9 1433648_at chr11 C 70834 15.5 3 158 Kank2 KN motif and ankyrin repeat domains 2 1460559_at chr9 A3 235041 15.5 3 159 Slc20a1 solute carrier family 20, member 1 1446441_at chr2 F1|2 73.0 cM 20515 15.5 3 160 Has2 hyaluronan synthase 2 1449169_at chr15 D1|15 31.2 cM 15117 15.5 3 161 Gng12 guanine nucleotide binding protein (G protein), gamma 12 1455089_at chr6 C1|6 30.0 cM 14701 15.5 3 162 Fap fibroblast activation protein 1417552_at chr2 C1.3|2 36.0 cM 14089 15.5 3 163 Lhfp lipoma HMGIC fusion partner 1433776_at chr3 C 108927 15.5 3 164 Degs1 degenerative spermatocyte homolog 1 (Drosophila) 1423346_at chr1 H5 13244 15.5 3 165 Mkx mohawk homeobox 1437492_at chr18 A1|18 3.0 cM 210719 15.5 3 166 Upk1b uroplakin 1B 1435831_at chr16 B5-C2 22268 15.5 3 167 Igf1 insulin-like growth factor 1 1419519_at chr10 C1|10 48.0 cM 16000 15.5 3 168 Sepp1 selenoprotein P, plasma, 1 1452141_a_at chr15 A1|15 5.9 cM 20363 15.5 3 169 Mef2a myocyte enhancer factor 2A 1421252_a_at chr7 C|7 33.0 cM 17258 15.5 3 170 Mxra8 matrix-remodelling associated 8 1452330_a_at chr4 E2|4 83.0 cM 74761 15.5 3 171 Rian RNA imprinted and accumulated in nucleus 1427580_a_at chr12 F1|12 54.5 cM 75745 15.5 3 172 Casp8 caspase 8 1424552_at chr1 B|1 30.1 cM 12370 15.5 3 173 Upk1b uroplakin 1B 1455464_x_at chr16 B5-C2 22268 15.5 3 174

PAGE 3

Mboat2 membrane bound O-acyltransferase domain containing 2 1425029_a_at chr12 A1.3 67216 15.5 3 175 A630007B06Rik RIKEN cDNA A630007B06 gene 1436073_at chr19 D2 213993 15.5 3 176 Bscl2 Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) 1437345_a_at chr19 A|19 4.0 cM 14705 15.5 3 177 Pcsk5 proprotein convertase subtilisin/kexin type 5 1451406_a_at chr19 B|19 18.0 cM 18552 15.5 3 178 Tmem100 transmembrane protein 100 1449533_at chr11 C 67888 15.5 3 179 Tubb6 tubulin, beta 6 1416431_at chr18 E1 67951 15.5 3 180 Degs1 degenerative spermatocyte homolog 1 (Drosophila) 1423345_at chr1 H5 13244 15.5 3 181 C78339 expressed sequence C78339 1433475_a_at chr13 A5 97863 15.5 3 182 Dusp3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) 1434472_at chr11 D 72349 15.5 3 183 1110067D22Rik RIKEN cDNA 1110067D22 gene 1424318_at chr11 A3.1|11 11.0 cM 216551 15.5 3 184 Rdh10 retinol dehydrogenase 10 (all-trans) 1426968_a_at chr1 A3|1 12.0 cM 98711 15.5 3 185 Rcn3 reticulocalbin 3, EF-hand calcium binding domain 1424382_at chr7 B4|7 23.1 cM 52377 15.5 3 186 F3 coagulation factor III 1417408_at chr3 G1|3 50.0 cM 14066 15.5 3 187 Bend5 BEN domain containing 5 1435351_at chr4 C7 67621 15.5 3 188 Angptl1 angiopoietin-like 1 1455224_at chr1 H1 72713 15.5 3 189 Tmed5 transmembrane emp24 protein transport domain containing 5 1424574_at chr5 E5 73130 15.5 3 190 Ifi30 interferon gamma inducible protein 30 1422476_at chr8 B3.3 65972 15.5 3 191 Gimap1 GTPase, IMAP family member 1 1449988_at chr6 B2.3 16205 15.5 3 192 Arfgap3 /// LOC100045474 ADP-ribosylation factor GTPase activating protein 3 /// similar to ADP-ribosylation factor GTPase activating protein 3 1426534_a_at chr15 E3 100045474 /// 66251 15.5 3 193 Snrk SNF related kinase 1448864_at chr9 F4 20623 15.5 3 194 Tmem9b TMEM9 domain family, member B 1417874_at chr7 E3 56786 15.5 3 195 Akap11 A kinase (PRKA) anchor protein 11 1434764_at chr14 D3 219181 15.5 3 196 Mef2a myocyte enhancer factor 2A 1427185_at chr7 C|7 33.0 cM 17258 15.5 3 197 Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1436297_a_at chr15 E1|15 66168 15.5 3 198 Edem3 ER degradation enhancer, mannosidase alpha-like 3 1460401_at chr1 G2 66967 15.5 3 199 Gm6768 /// Ncoa4 predicted gene 6768 /// nuclear receptor coactivator 4 1420808_at chr12 F2 /// chr14 B 27057 /// 627557 15.5 3 200 Slc25a24 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 1452717_at chr3 F3 229731 15.5 3 201 Rhoq ras homolog gene family, member Q 1427918_a_at chr17 E4|17 56.0 cM 104215 15.5 3 202 Dsel dermatan sulfate epimerase-like 1438407_at chr1 E2.2 319901 15.5 3 203 Dnajc21 DnaJ (Hsp40) homolog, subfamily C, member 21 1460711_at chr15 A2 78244 15.5 3 204 Shisa5 shisa homolog 5 (Xenopus laevis) 1437503_a_at chr9 F2 66940 15.5 3 205 Il1rap interleukin 1 receptor accessory protein 1421844_at chr16 B2 16180 15.5 3 206 Chst1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 1449147_at --76969 15.5 3 207 Upk1b uroplakin 1B 1457065_at chr16 B5-C2 22268 15.5 3 208 Prkcdbp protein kinase C, delta binding protein 1423771_at chr7 F1 109042 15.5 3 209 Glt8d2 glycosyltransferase 8 domain containing 2 1429402_at chr10 C1 74782 15.5 3 210 B630019K06Rik RIKEN cDNA B630019K06 gene 1433452_at chrX A1.1 102941 15.5 3 211 Rab8b RAB8B, member RAS oncogene family 1426799_at chr9 C 235442 15.5 3 212 Itm2a integral membrane protein 2A 1423608_at chrX A2-A3 16431 15.5 3 213 Rian RNA imprinted and accumulated in nucleus 1452899_at chr12 F1|12 54.5 cM 75745 15.5 3 214 Ppapdc1b phosphatidic acid phosphatase type 2 domain containing 1B 1428154_s_at chr8 A3|8 71910 15.5 3 215 Pde1a phosphodiesterase 1A, calmodulin-dependent 1449298_a_at chr2 D 18573 15.5 3 216 Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 1416473_a_at chr9 C 56741 15.5 3 217 Tgfbr2 transforming growth factor, beta receptor II 1426397_at chr9 F3|9 69.0 cM 21813 15.5 3 218 Vsnl1 visinin-like 1 1420955_at chr12 A2 26950 15.5 3 219 Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 1456530_x_at chr4 D2.1 54325 15.5 3 220 Colec12 collectin sub-family member 12 1419693_at chr18 A1 140792 15.5 3 221 Ank progressive ankylosis 1450627_at chr15 B1|15 14.4 cM 11732 15.5 3 222 H2-D1 histocompatibility 2, D region locus 1 1425545_x_at chr17 B1|17 19.09 cM 14964 15.5 3 223 Slain1 SLAIN motif family, member 1 1424824_at chr14 E2.3 105439 15.5 3 224 Ndrg1 N-myc downstream regulated gene 1 1456174_x_at chr15 D2 17988 15.5 3 225 Ppap2b phosphatidic acid phosphatase type 2B 1448908_at chr4 C6|4 52.7 cM 67916 15.5 3 226 Scel sciellin 1422837_at chr14 E 64929 15.5 3 227 Smoc1 SPARC related modular calcium binding 1 1448321_at chr12 D1 64075 15.5 3 228 Sdpr serum deprivation response 1416779_at chr1 C1.1 20324 15.5 3 229 Islr immunoglobulin superfamily containing leucine-rich repeat 1418450_at chr9 B 26968 15.5 3 230 Dgat2 diacylglycerol O-acyltransferase 2 1422678_at chr7 F1 67800 15.5 3 231 Clu /// LOC100046120 clusterin /// similar to clusterin 1437689_x_at chr14 D1|14 28.0 cM 100046120 /// 12759 15.5 3 232 Thbd thrombomodulin 1448529_at chr2 G3|2 84.0 cM 21824 15.5 3 233 Kcns3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 1457799_at chr12 A1.1|12 2.5 cM 238076 15.5 3 234 Zfp664 zinc finger protein 664 1437047_at chr5 F 269704 15.5 3 235 Col5a2 collagen, type V, alpha 2 1450625_at chr1 C1 12832 15.5 3 236 Acsl1 acyl-CoA synthetase long-chain family member 1 1450643_s_at chr8 B2 14081 15.5 3 237 Sox7 SRY-box containing gene 7 1416564_at chr14 C3 20680 15.5 3 238 Myadm myeloid-associated differentiation marker 1439389_s_at chr7 A1|7 4.0 cM 50918 15.5 3 239 Pkd2 polycystic kidney disease 2 1441870_s_at chr5 E5|5 55.0 cM 18764 15.5 3 240 Clcn5 chloride channel 5 1420295_x_at chrX A1.1|X 0.8 cM 12728 15.5 3 241 Zdhhc14 zinc finger, DHHC domain containing 14 1438619_x_at chr17 A1 224454 15.5 3 242 Fam70a family with sequence similarity 70, member A 1439006_x_at chrX A3.3 245386 15.5 3 243 Ggct gamma-glutamyl cyclotransferase 1435695_a_at chr6 26.0 cM 110175 15.5 3 244 Rab27b RAB27b, member RAS oncogene family 1417214_at chr18 E2|18 45.0 cM 80718 15.5 3 245 Ugt1a1 /// Ugt1a10 /// Ugt1a2 /// Ugt1a5 /// Ugt1a6a /// Ugt1a6b /// Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A1 /// UDP glycosyltransferase 1 family, polypeptide A10 1426261_s_at chr1 D /// chr1 D|1 51.7 cM 22236 /// 394430 /// 394432 /// 394433 /// 394434 /// 394435 /// 394436 // 15.5 3 246 Nrk Nik related kinase 1450079_at chrX F1|X 53.0 cM 27206 15.5 3 247 Cnrip1 cannabinoid receptor interacting protein 1 1433695_at chr11 A3.1 380686 15.5 3 248 H2-L histocompatibility 2, D region 1451931_x_at chr17 19.13 cM 14980 15.5 3 249 Sfrp2 secreted frizzled-related protein 2 1448201_at chr3 E3|3 38.5 cM 20319 15.5 3 250 Cxcl12 chemokine (C-X-C motif) ligand 12 1448823_at chr6 F1|6 53.0 cM 20315 15.5 3 251 Ctsk cathepsin K 1450652_at chr3 F2.1|3 47.9 cM 13038 15.5 3 252 Fam57a family with sequence similarity 57, member A 1435076_at chr11 B5 116972 15.5 3 253 Armcx3 armadillo repeat containing, X-linked 3 1460359_at chrX E3 71703 15.5 3 254 Ctss cathepsin S 1448591_at chr3 F2.1|3 42.7 cM 13040 15.5 3 255 Klf4 Kruppel-like factor 4 (gut) 1417394_at chr4 B3|4 19.7 cM 16600 15.5 3 256 Id4 /// LOC100045546 inhibitor of DNA binding 4 /// similar to Id4 1423259_at chr13 B|13 31.0 cM 100045546 /// 15904 15.5 3 257 Ptx3 pentraxin related gene 1418666_at chr3 E1|3 33.8 cM 19288 15.5 3 258 Spnb2 spectrin beta 2 1444089_at chr11 A3.3|11 13.0 cM 20742 15.5 3 259 Klhl2 kelch-like 2, Mayven (Drosophila) 1426978_at chr8 B3.1 77113 15.5 3 260 Tbx18 T-box18 1449871_at chr9 E3.2|9 48.5 cM 76365 15.5 3 261 LOC100045546 similar to Id4 1450928_at --100045546 15.5 3 262

PAGE 4

Fermt3 fermitin family homolog 3 (Drosophila) 1456014_s_at chr19 A 108101 15.5 3 263 Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 1455994_x_at chr4 D2.1 54325 15.5 3 264 Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 1425676_a_at chr4 D2.1 54325 15.5 3 265 Fam102b family with sequence similarity 102, member B 1434828_at chr3 F3 329739 15.5 3 266 H2-D1 histocompatibility 2, D region locus 1 1451784_x_at chr17 B1|17 19.09 cM 14964 15.5 3 267 1110032F04Rik RIKEN cDNA 1110032F04 gene 1456509_at chr3 E1 68725 15.5 3 268 Clca3 chloride channel calcium activated 3 1416306_at chr3 H2|3 74.5 cM 23844 15.5 4 269 Fbln7 fibulin 7 1460412_at chr2 F3 70370 15.5 4 270 Ccl21a /// Ccl21b /// Ccl21c chemokine (C-C motif) ligand 21A /// chemokine (C-C motif) ligand 21B /// chemokine (C-C motif) ligand 21C (leucine) 1419426_s_at chr4 A5|4 13.3 cM /// chr4 A5|4 13.34 cM 18829 /// 20298 /// 65956 15.5 4 271 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1439036_a_at chr1 H2.2|1 86.8 cM 11931 15.5 4 272 Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a 1416318_at chr13 A4|13 12.0 cM 66222 15.5 4 273 Lor loricrin 1448745_s_at chr3 F1|3 42.1 cM 16939 15.5 4 274 2310002J15Rik RIKEN cDNA 2310002J15 gene 1450532_at chr2 A3 67859 15.5 4 275 1110020C03Rik RIKEN cDNA 1110020C03 gene 1429869_at chr4 D2.1 68625 15.5 4 276 Zcchc5 zinc finger, CCHC domain containing 5 1437355_at chrX D 213436 15.5 4 277 Serpinb7 serine (or cysteine) peptidase inhibitor, clade B, member 7 1449500_at chr1 D 116872 15.5 4 278 Lor loricrin 1420183_at chr3 F1|3 42.1 cM 16939 15.5 4 279 Serpinb11 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11 1449451_at chr1 E2.1 66957 15.5 4 280 Fam3b family with sequence similarity 3, member B 1425122_at chr16 C4|16 71.3 cM 52793 15.5 4 281 Trf transferrin 1425546_a_at chr9 F1-F3|9 56.0 cM 22041 15.5 4 282 Gpx3 glutathione peroxidase 3 1449106_at chr11 B3-B5 14778 15.5 4 283 Gsta1 /// Gsta2 glutathione S-transferase, alpha 1 (Ya) /// glutathione S-transferase, alpha 2 (Yc2) 1421041_s_at chr9 E1|9 43.0 cM /// chr9 E1|9 44.0 cM 14857 /// 14858 15.5 4 284 Sprr3 small proline-rich protein 3 1422401_at chr3 F1|3 45.2 cM 20766 15.5 4 285 Rarres1 retinoic acid receptor responder (tazarotene induced) 1 1438055_at chr3 E1 109222 15.5 4 286 Sbsn suprabasin 1439630_x_at chr7A3|7 282619 15.5 4 287 Ly6g6c lymphocyte antigen 6 complex, locus G6C 1449789_x_at chr17 B1 68468 15.5 4 288 Acer1 alkaline ceramidase 1 1439183_at chr17 D 171168 15.5 5 289 Hrnr hornerin 1451613_at --68723 15.5 5 290 Lce3f /// LOC630971 late cornified envelope 3F /// hypothetical protein LOC630971 1456248_at chr3 F1 630971 /// 69520 15.5 5 291 Stmn1 stathmin 1 1415849_s_at chr4 D3|4 65.7 cM 16765 13.5 6 292 Orc1l origin recognition complex, subunit 1-like (S.cereviaiae) 1422663_at chr4 D 18392 13.5 6 293 Sip1 survival of motor neuron protein interacting protein 1 1451044_at chr12 C2 66603 13.5 6 294 Guk1 guanylate kinase 1 1416395_at chr11 B1.3 14923 13.5 6 295 Pdgfa platelet derived growth factor, alpha 1418711_at chr5 G2|5 82.0 cM 18590 13.5 6 296 Thoc4 THO complex 4 1417724_at chr11 E2 21681 13.5 6 297 Pabpn1 poly(A) binding protein, nuclear 1 1422850_at chr14 C3|14 19.5 cM 54196 13.5 6 298 D030056L22Rik RIKEN cDNA D030056L22 gene 1423879_at chr19 B 225995 13.5 6 299 Fastkd2 FAST kinase domains 2 1426741_a_at chr1 C2 75619 13.5 6 300 Sfrs7 splicing factor, arginine/serine-rich 7 1424883_s_at chr17 E3 225027 13.5 6 301 Dnajc6 DnaJ (Hsp40) homolog, subfamily C, member 6 1433596_at chr4 C6 72685 13.5 6 302 Rabl2a RAB, member of RAS oncogene family-like 2A 1431931_a_at chr15 E3 68708 13.5 6 303 Plekho1 pleckstrin homology domain containing, family O member 1 1417128_at chr3 F2 67220 13.5 6 304 Sgol1 shugoshin-like 1 (S. pombe) 1418919_at chr17 C 72415 13.5 6 305 Dsg2 desmoglein 2 1425619_s_at chr18 A2|18 7.05 cM 13511 13.5 6 306 Srrm1 serine/arginine repetitive matrix 1 1450045_at chr4 D3 51796 13.5 6 307 Gmnn geminin 1417506_at chr13 A3.1 57441 13.5 6 308 Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein 1442058_s_at chr11 D 19183 13.5 6 309 Pkp2 plakophilin 2 1449799_s_at chr16 B1 67451 13.5 6 310 1110012J17Rik RIKEN cDNA 1110012J17 gene 1429053_at chr17 E1.1 68617 13.5 6 311 Traip TRAF-interacting protein 1420707_a_at chr9 F1-F2|9 60.0 cM 22036 13.5 6 312 Dab1 disabled homolog 1 (Drosophila) 1421100_a_at chr4 C6|4 52.7 cM 13131 13.5 6 313 Klhl11 kelch-like 11 (Drosophila) 1427218_at chr11 D 217194 13.5 6 314 LOC676546 /// Mmd similar to monocyte to macrophage differentiation-associated /// monocyte to macrophage differentiation-associated 1435645_at chr11 C 67468 /// 676546 13.5 6 315 Bex1 brain expressed gene 1 1448595_a_at chrX F1|X 57.5 cM 19716 13.5 6 316 Tubb3 tubulin, beta 3 1415978_at chr8 E1 22152 13.5 6 317 1110034G24Rik RIKEN cDNA 1110034G24 gene 1437617_x_at --73747 13.5 6 318 5730407M17Rik RIKEN cDNA 5730407M17 gene 1431347_at chr2 B 70480 13.5 6 319 H2afv H2A histone family, member V 1428029_a_at chr11 A1 77605 13.5 6 320 Gpr107 G protein-coupled receptor 107 1459788_at chr2 B 277463 13.5 6 321 Wnt6 wingless-related MMTV integration site 6 1419708_at chr1 C3 22420 13.5 6 322 LOC100134980 hypothetical LOC100134980 1425421_at chr7 F3 100134980 13.5 6 323 C630004H02Rik RIKEN cDNA C630004H02 gene 1457518_at chr11 E2 217310 13.5 6 324 Anxa6 Annexin A6 1442288_at chr11 B1.3|11 29.5 cM 11749 13.5 6 325 Cldn7 claudin 7 1448393_at chr11 B4 53624 13.5 6 326 Sfrs3 splicing factor, arginine/serine-rich 3 (SRp20) 1416150_a_at chr17 A3.3|17 11.0 cM 20383 13.5 6 327 Dhfr dihydrofolate reductase 1419172_at chr13 C3|13 43.0 cM 13361 13.5 6 328 Bex2 brain expressed X-linked 2 1417388_at chrX F1|X 57.5 cM 12069 13.5 6 329 Sltm SAFB-like, transcription modulator 1456683_at chr9 D 66660 13.5 6 330 Trp53rk transformation related protein 53 regulating kinase 1419683_at chr2 H3 76367 13.5 6 331 Ovol2 ovo-like 2 (Drosophila) 1449205_at chr2 H1 107586 13.5 6 332 Lrrc56 leucine rich repeat containing 56 1427890_a_at chr7 F5 70552 13.5 6 333 Prdx2 peroxiredoxin 2 1430979_a_at chr8 C3|8 36.0 cM 21672 13.5 6 334 Snrpn /// Snurf small nuclear ribonucleoprotein N /// SNRPN upstream reading frame 1435716_x_at chr7 C /// chr7 C|7 29.0 cM 20646 /// 84704 13.5 6 335 ----1446234_at ----13.5 6 336 Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase 1436704_x_at --108156 13.5 6 337 2900010M23Rik RIKEN cDNA 2900010M23 gene 1436810_x_at chr17 B1 67267 13.5 6 338 Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 1455898_x_at chr6 F2|6 59.0 cM 20527 13.5 6 339 ----1457438_at ----13.5 6 340 Msx1 homeobox, msh-like 1 1448601_s_at chr5 B3|5 21.0 cM 17701 13.5 6 341 1810022C23Rik RIKEN cDNA 1810022C23 gene 1451588_at chr13 A3.3 69123 13.5 6 342 Zfp207 zinc finger protein 207 1455092_at chr11 B5 22680 13.5 6 343 Cd151 CD151 antigen 1456085_x_at chr7 F5|7 23.5 cM 12476 13.5 6 344 3010003L21Rik RIKEN cDNA 3010003L21 gene 1415875_at chr6 G3 109163 13.5 6 345 Batf3 basic leucine zipper transcription factor, ATF-like 3 1453076_at chr1 H6 381319 13.5 6 346 ----1456216_at ----13.5 6 347 Cxcl14 chemokine (C-X-C motif) ligand 14 1418456_a_at chr13 B1 57266 13.5 6 348 Fip1l1 FIP1 like 1 (S. cerevisiae) 1443586_at chr5 D 66899 13.5 6 349 Rprm reprimo, TP53 dependent G2 arrest mediator candidate 1422552_at chr2 C1 67874 13.5 6 350

PAGE 5

Krtcap3 keratinocyte associated protein 3 1432474_a_at chr5 B1 69815 13.5 6 351 1500004F05Rik RIKEN cDNA 1500004F05 gene 1456899_at chr8 A4 69765 13.5 6 352 Mrpl11 mitochondrial ribosomal protein L11 1437131_x_at chr19 A 66419 13.5 6 353 Acyp1 acylphosphatase 1, erythrocyte (common) type 1439013_x_at chr12 D2 66204 13.5 6 354 Snhg7 Small nucleolar RNA host gene (non-protein coding) 7 1447483_s_at --72091 13.5 6 355 Wfdc2 WAP four-disulfide core domain 2 1424351_at chr2 H3 67701 13.5 6 356 Polr3k polymerase (RNA) III (DNA directed) polypeptide K 1439266_a_at chr2 H4 67005 13.5 6 357 2610002D18Rik RIKEN cDNA 2610002D18 gene 1429812_at chr4 D3 69885 13.5 6 358 Arfgap3 ADP-ribosylation factor GTPase activating protein 3 1430904_at chr15 E3 66251 13.5 6 359 Chd7 chromodomain helicase DNA binding protein 7 1437745_at chr4 A1|4 1.0 cM 320790 13.5 6 360 6430706D22Rik RIKEN cDNA 6430706D22 gene 1454686_at --78605 13.5 6 361 Usp14 ubiquitin specific peptidase 14 1439201_at chr18 A1|18 2.0 cM 59025 13.5 6 362 Pdlim7 PDZ and LIM domain 7 1443785_x_at chr13 B2 67399 13.5 6 363 Fam60a family with sequence similarity 60, member A 1448126_at --56306 13.5 6 364 ----1439336_at ----13.5 6 365 ----1446410_at ----13.5 6 366 8030447M02Rik RIKEN cDNA 8030447M02 gene 1458601_at --399578 13.5 6 367 ----1446384_at ----13.5 6 368 Fkbp4 /// LOC100048743 FK506 binding protein 4 /// similar to FK506 binding protein 4 1416363_at chr6 F3 100048743 /// 14228 13.5 6 369 Prss22 protease, serine, 22 1420352_at chr17 A3.3|17 10.7 cM 70835 13.5 6 370 Gm5871 /// Smndc1 predicted gene 5871 /// survival motor neuron domain containing 1 1443396_at chr19 D2 /// chr5 F 545792 /// 76479 13.5 6 371 Cenpa centromere protein A 1450842_a_at chr5 B1|5 18.0 cM 12615 13.5 6 372 ----1446615_at ----13.5 6 373 Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 1421468_at chr2 C1.1 16519 13.5 6 374 AI449595 EST AI449595 1437677_at --58901 13.5 6 375 Anapc11 Anaphase promoting complex subunit 11 1447897_x_at chr11 E2 66156 13.5 6 376 ----1442628_at ----13.5 6 377 Rint1 RAD50 interactor 1 1431147_at chr5 A3 72772 13.5 6 378 2700094K13Rik RIKEN cDNA 2700094K13 gene 1436349_at chr2 D 72657 13.5 6 379 Nr2c2 nuclear receptor subfamily 2, group C, member 2 1454167_at chr6 D1 22026 13.5 6 380 Ube2t ubiquitin-conjugating enzyme E2T (putative) 1422462_at chr1 E4 67196 13.5 6 381 Fis1 fission 1 (mitochondrial outer membrane) homolog (yeast) 1443819_x_at chr5 G1 66437 13.5 6 382 Siva1 SIVA1, apoptosis-inducing factor 1426323_x_at chr12 F2 30954 13.5 6 383 Tbc1d9 TBC1 domain family, member 9 1431253_s_at chr8 C3 71310 13.5 6 384 Mkks McKusick-Kaufman syndrome protein 1454014_a_at chr2 F3 59030 13.5 6 385 Slc25a33 solute carrier family 25, member 33 1424211_at chr4 E1 70556 13.5 6 386 Bnc1 basonuclin 1 1424890_at chr7 D3 12173 13.5 6 387 Trnau1ap tRNA selenocysteine 1 associated protein 1 1428746_a_at chr4 D3|4 71787 13.5 6 388 Apcdd1 Adenomatosis polyposis coli down-regulated 1 1443639_at chr18 E1 494504 13.5 6 389 Cldn6 claudin 6 1417845_at chr17 A3.3 54419 13.5 6 390 Ndst3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1453777_a_at chr3 G3 83398 13.5 6 391 6820431F20Rik RIKEN cDNA 6820431F20 gene 1436740_at chr8 A1.3 381598 13.5 6 392 Kdm5b lysine (K)-specific demethylase 5B 1457482_at chr1 E4|1 72.0 cM 75605 13.5 6 393 ----1442750_at ----13.5 6 394 Lman1 lectin, mannose-binding, 1 1444037_at chr18 E1 70361 13.5 6 395 ----1440431_at ----13.5 6 396 Cklf chemokine-like factor 1451832_at chr8 D3 75458 13.5 6 397 5730507N06Rik RIKEN cDNA 5730507N06 gene 1457642_at --70622 13.5 6 398 2810410L24Rik RIKEN cDNA 2810410L24 gene 1429510_at chr11 E2 100042332 13.5 6 399 Nrf1 Nuclear respiratory factor 1 1434627_at chr6 A3.3|6 6.5 cM 18181 13.5 6 400 Phip pleckstrin homology domain interacting protein 1438535_at chr9 E3.1 83946 13.5 6 401 ----1455744_at ----13.5 6 402 Cox4i2 cytochrome c oxidase subunit IV isoform 2 1421373_at chr2 H2 84682 13.5 6 403 Mrpl17 mitochondrial ribosomal protein L17 1458027_at chr7 F1 27397 13.5 6 404 Dusp9 dual specificity phosphatase 9 1454737_at chrX B 75590 13.5 6 405 Hist1h3a /// Hist1h3b /// Hist1h3c /// Hist1h3d /// Hist1h3e /// Hist1h3f /// histone cluster 1, H3a /// histone cluster 1, H3b /// histone cluster 1, H3c /// histone cluster 1, H3d /// histone cluster 1, H3e /// histone cluster 1, H3f /// histone cluster 1, H3g /// histone cluster 1, H3h /// histone cluster 1, H3i /// histone clust 1460314_s_at chr13 A2-A3 /// chr13 A2-A3|13 12.0 cM /// chr3 F1-F2 /// c 15077 /// 260423 /// 319148 /// 319149 /// 319150 /// 319151 /// 319152 // 13.5 6 406 Nlrp3 NLR family, pyrin domain containing 3 1425412_at chr11 B1.3 216799 13.5 6 407 Myo19 myosin XIX 1459265_at chr11 B5 66196 13.5 6 408 Rpp30 Ribonuclease P/MRP 30 subunit (human) 1447970_at chr19 C2 54364 13.5 6 409 Hmga2 high mobility group AT-hook 2 1450781_at chr10 D2|10 67.5 cM 15364 13.5 6 410 ----1457398_at ----13.5 6 411 Cdc25c cell division cycle 25 homolog C (S. pombe) 1422252_a_at chr18 B1|18 15.0 cM 12532 13.5 6 412 ----1437600_at ----13.5 6 413 AL023051 expressed sequence AL023051 1444675_at --100782 13.5 6 414 ----1444858_at ----13.5 6 415 ----1426060_at ----13.5 6 416 ----1443513_at ----13.5 6 417 AI605517 expressed sequence AI605517 1457797_at --106622 13.5 6 418 ----1439200_x_at ----13.5 6 419 Phf20 PHD finger protein 20 1458017_at chr2 H1 228829 13.5 6 420 Pus3 pseudouridine synthase 3 1429222_at chr9 A5.3 67049 13.5 6 421 0610038B21Rik RIKEN cDNA 0610038B21 gene 1430930_at --70345 13.5 6 422 Fam54a family with sequence similarity 54, member A 1432013_a_at chr10 A3 71804 13.5 6 423 ----1445837_at ----13.5 6 424 Cxcl14 chemokine (C-X-C motif) ligand 14 1418457_at chr13 B1 57266 13.5 6 425 Wnt7a wingless-related MMTV integration site 7A 1423367_at chr6 D1|6 39.5 cM 22421 13.5 6 426 4632427E13Rik RIKEN cDNA 4632427E13 gene 1429331_at chr7 E1 666737 13.5 6 427 Zmym4 zinc finger, MYM-type 4 1438460_at chr4 D2.2 67785 13.5 6 428 ----1444557_at ----13.5 6 429 Gm8276 /// Pabpc1 predicted gene 8276 /// poly(A) binding protein, cytoplasmic 1 1453840_at chr15 C /// chr3 D|3 18458 /// 666756 13.5 6 430 2810410L24Rik RIKEN cDNA 2810410L24 gene 1438972_x_at chr11 E2 100042332 13.5 6 431 6720475J19Rik RIKEN cDNA 6720475J19 gene 1423071_x_at chr19 A 68157 13.5 6 432 4632427E13Rik RIKEN cDNA 4632427E13 gene 1442155_at chr7 E1 666737 13.5 6 433 4930588G05Rik RIKEN cDNA 4930588G05 gene 1430175_at --78817 13.5 6 434 Stag1 Stromal antigen 1 1441724_at chr9 F1 20842 13.5 6 435 6820431F20Rik RIKEN cDNA 6820431F20 gene 1437717_x_at chr8 A1.3 381598 13.5 6 436 ----1442322_at ----13.5 6 437 Tarbp2 TAR (HIV) RNA binding protein 2 1438952_x_at chr15 F|15 61.7 cM 21357 13.5 6 438

PAGE 6

Thrap3 thyroid hormone receptor associated protein 3 1452125_at chr4 D2.2 230753 13.5 6 439 Lgtn Ligatin 1437720_at chr1 F|1 69.1 cM 16865 13.5 6 440 AI480624 expressed sequence AI480624 1442197_at --102540 13.5 6 441 Fbxl7 F-box and leucine-rich repeat protein 7 1440441_at chr15 B1 448987 13.5 6 442 Dlx1 distal-less homeobox 1 1449470_at chr2 C2|2 44.0 cM 13390 13.5 6 443 ----1440121_at ----13.5 6 444 Rtn4 reticulon 4 1435284_at chr11 A3.3 68585 13.5 6 445 ----1441467_at ----13.5 6 446 ----1442914_at ----13.5 6 447 D530037H12Rik RIKEN cDNA D530037H12 gene 1437917_at --96893 13.5 6 448 ----1460126_at ----13.5 6 449 Fubp1 far upstream element (FUSE) binding protein 1 1437544_at chr3 H3|3 70.5 cM 51886 13.5 6 450 ----1443090_at ----13.5 6 451 Rbm5 RNA binding motif protein 5 1456262_at chr9 F1 83486 13.5 6 452 ----1439672_at ----13.5 6 453 Fn1 fibronectin 1 1437218_at chr1 C1-C5|1 36.1 cM 14268 13.5 6 454 Ranbp3 RAN binding protein 3 1457711_at chr17 D 71810 13.5 6 455 Rsrc2 arginine/serine-rich coiled-coil 2 1442083_at chr5 F 208606 13.5 6 456 ----1443592_at ----13.5 6 457 Hmga2 high mobility group AT-hook 2 1450780_s_at chr10 D2|10 67.5 cM 15364 13.5 6 458 Zcchc11 zinc finger, CCHC domain containing 11 1439631_at chr4 C7 230594 13.5 6 459 Arrdc3 Arrestin domain containing 3 1459253_at chr13 C3 105171 13.5 6 460 ----1444195_at ----13.5 6 461 ----1438072_at ----13.5 6 462 ----1444598_at ----13.5 6 463 ----1438104_at ----13.5 6 464 Acot6 acyl-CoA thioesterase 6 1460388_at chr12 D1 217700 13.5 6 465 ----1439097_at ----13.5 6 466 Fmod fibromodulin 1415939_at chr1 E4|1 74.3 cM 14264 13.5 7 467 Cdk4 /// LOC640611 cyclin-dependent kinase 4 /// similar to Cell division protein kinase 4 (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) 1422440_at chr10 D3 12567 /// 640611 13.5 7 468 Ecd ecdysoneless homolog (Drosophila) 1424593_at chr14 B 70601 13.5 7 469 Pitx2 paired-like homeodomain transcription factor 2 1424797_a_at chr3 G3|3 57.7 cM 18741 13.5 7 470 Ldhb lactate dehydrogenase B 1448237_x_at chr6 G2|6 62.0 cM 16832 13.5 7 471 ----1434568_at ----13.5 7 472 Mrpl28 mitochondrial ribosomal protein L28 1416284_at chr17 B1 68611 13.5 7 473 Tbpl1 TATA box binding protein-like 1 1431415_a_at chr10 A3 237336 13.5 7 474 Nuak1 NUAK family, SNF1-like kinase, 1 1438684_at chr10 C1 77976 13.5 7 475 Jrk jerky 1418409_at chr15 D3|15 42.8 cM 16469 13.5 7 476 Uba2 ubiquitin-like modifier activating enzyme 2 1448283_a_at chr7 B1 50995 13.5 7 477 Grwd1 glutamate-rich WD repeat containing 1 1455841_s_at chr7 B4 101612 13.5 7 478 Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 1422460_at chr6 C1|6 30.3 cM 56150 13.5 7 479 Zswim3 zinc finger, SWIM domain containing 3 1428313_at chr2 H3 67538 13.5 7 480 Hmgb3 high mobility group box 3 1416155_at chrX A1 15354 13.5 7 481 Commd6 COMM domain containing 6 1435863_at chr14 E2.3 66200 13.5 7 482 Ctnnd2 /// LOC100045979 catenin (cadherin associated protein), delta 2 /// similar to arm-repeat protein NPRAP/neurojungin 1422592_at chr15 B2 100045979 /// 18163 13.5 7 483 Cdca3 cell division cycle associated 3 1452040_a_at chr6 F2|6 60.19 cM 14793 13.5 7 484 Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 1455988_a_at chr5 G1.3 12466 13.5 7 485 Notch1 Notch gene homolog 1 (Drosophila) 1418633_at chr2 A3|2 15.0 cM 18128 13.5 7 486 Cdca4 cell division cycle associated 4 1423683_at chr12 F2 71963 13.5 7 487 Hoxa9 homeo box A9 1421579_at chr6 B3|6 26.32 cM 15405 13.5 7 488 Wdyhv1 WDYHV motif containing 1 1434144_s_at chr15 D2|15 76773 13.5 7 489 Snhg10 small nucleolar RNA host gene (non-protein coding) 10 1447993_a_at chr12 E 69434 13.5 7 490 Panx1 pannexin 1 1416379_at chr9 A2 55991 13.5 7 491 Luc7l Luc7 homolog (S. cerevisiae)-like 1428255_at chr17 B1|17 11.8 cM 66978 13.5 7 492 Cd151 CD151 antigen 1451232_at chr7 F5|7 23.5 cM 12476 13.5 7 493 5133400G04Rik RIKEN cDNA 5133400G04 gene 1430023_at chr18 B3 71242 13.5 7 494 Cdc2a cell division cycle 2 homolog A (S. pombe) 1448314_at chr10 B5.3|10 38.0 cM 12534 13.5 7 495 Mrps35 mitochondrial ribosomal protein S35 1452111_at chr6 G3 232536 13.5 7 496 Pnpla6 patatin-like phospholipase domain containing 6 1416517_at chr8 A1.1|8 1.1 cM 50767 13.5 7 497 Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 1424118_a_at chr2 C3 66442 13.5 7 498 ----1442044_at ----13.5 7 499 Rbm4 RNA binding motif protein 4 1416920_at chr19 A 19653 13.5 7 500 Ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1416070_a_at chr1 E2 66942 13.5 7 501 Fkbp1b FK506 binding protein 1b 1449429_at chr12 A1.1 14226 13.5 7 502 Apex1 apurinic/apyrimidinic endonuclease 1 1416135_at chr14 C3|14 18.5 cM 11792 13.5 7 503 5730494M16Rik RIKEN cDNA 5730494M16 gene 1441960_x_at chr18 A2 66648 13.5 7 504 Ldhb lactate dehydrogenase B 1416183_a_at chr6 G2|6 62.0 cM 16832 13.5 7 505 Tbc1d7 TBC1 domain family, member 7 1428598_at chr13 A4 67046 13.5 7 506 Nob1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1454957_at chr8 D2 67619 13.5 7 507 Eri2 exoribonuclease 2 1435390_at chr7 F3|7 71151 13.5 7 508 Sfrs2 splicing factor, arginine/serine-rich 2 (SC-35) 1452439_s_at chr11 E2|11 73.0 cM 20382 13.5 7 509 Hmgn1 high mobility group nucleosomal binding domain 1 1422495_a_at chr16 C4|16 69.8 cM 15312 13.5 7 510 Sf3b4 splicing factor 3b, subunit 4 1424619_at chr3 F2.1 107701 13.5 7 511 Zscan12 zinc finger and SCAN domain containing 12 1451281_at chr13 A3.1 22758 13.5 7 512 Ldhb lactate dehydrogenase B 1455235_x_at chr6 G2|6 62.0 cM 16832 13.5 7 513 Sac3d1 SAC3 domain containing 1 1417035_at chr19 A 66406 13.5 7 514 Rbbp4 retinoblastoma binding protein 4 1434892_x_at --19646 13.5 7 515 Med29 mediator complex subunit 29 1421903_at chr7 A3 67224 13.5 7 516 Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 1422665_a_at chr10 A1|10 7.0 cM 18537 13.5 7 517 Pitx2 paired-like homeodomain transcription factor 2 1450482_a_at chr3 G3|3 57.7 cM 18741 13.5 7 518 Tubg1 tubulin, gamma 1 1417144_at chr11 D|11 60.0 cM 103733 13.5 7 519 Ndufa7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a) 1436567_a_at chr17 B1 66416 13.5 7 520 Tmem183a transmembrane protein 183A 1417199_at chr1 E4 57439 13.5 7 521 Tom1l1 target of myb1-like 1 (chicken) 1451117_a_at chr11 D|11 53.0 cM 71943 13.5 7 522 Birc5 baculoviral IAP repeat-containing 5 1424278_a_at chr11 E2 11799 13.5 7 523 Foxk2 forkhead box K2 1428353_at chr11 E2 68837 13.5 7 524 Tia1 cytotoxic granule-associated RNA binding protein 1 1416812_at chr6 D2 21841 13.5 7 525 Ccnjl cyclin J-like 1459978_x_at chr11 B1.1 380694 13.5 7 526

PAGE 7

G2e3 G2/M-phase specific E3 ubiquitin ligase 1455355_at chr12 C1 217558 13.5 7 527 2310030G06Rik RIKEN cDNA 2310030G06 gene 1449357_at chr9 A5.3 66952 13.5 7 528 Pqlc3 PQ loop repeat containing 1424906_at chr12 A1.1 217430 13.5 7 529 N6amt2 N-6 adenine-specific DNA methyltransferase 2 (putative) 1435270_x_at chr14 C3 68043 13.5 7 530 Gm14176 /// Gm5931 /// LOC100044900 /// Ube2i predicted gene 14176 /// ubiquitin-conjugating enzyme E2I pseudogene /// similar to Chain A, Crystal Structure Of Human Rangap1-Ubc9 /// ubiquitin-conjugating enzyme E2I 1422712_a_at chr17 A3.3 /// chr2 H1|2 /// chrX A1.1 100043681 /// 100044900 /// 22196 /// 546265 13.5 7 531 Nudt1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1449349_at chr5 G1 17766 13.5 7 532 Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 1423517_at chr5 G1.3 12466 13.5 7 533 Rpl7l1 ribosomal protein L7-like 1 1452049_at chr17 C 66229 13.5 7 534 Nme6 non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase) 1448574_at chr9 F2 54369 13.5 7 535 Tk2 thymidine kinase 2, mitochondrial 1426100_a_at chr8 D3 57813 13.5 7 536 Fbxo5 F-box protein 5 1429499_at chr10 A1 67141 13.5 7 537 Cisd2 CDGSH iron sulfur domain 2 1428441_at chr3 G3 67006 13.5 7 538 Hes6 hairy and enhancer of split 6 (Drosophila) 1436050_x_at chr1 D 55927 13.5 7 539 C330018D20Rik RIKEN cDNA C330018D20 gene 1439783_at chr18 D3 77422 13.5 7 540 Lsm6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1437108_at chr8 C1 78651 13.5 7 541 LOC100048338 /// Pdlim1 similar to Pdlim1 protein /// PDZ and LIM domain 1 (elfin) 1416554_at chr19 D1 100048338 /// 54132 13.5 7 542 Sfrs3 splicing factor, arginine/serine-rich 3 (SRp20) 1454993_a_at chr17 A3.3|17 11.0 cM 20383 13.5 7 543 Olfm1 olfactomedin 1 1426562_a_at chr2 A3 56177 13.5 7 544 Dus1l dihydrouridine synthase 1-like (S. cerevisiae) 1435734_x_at chr11 E2 68730 13.5 7 545 Mettl4 methyltransferase like 4 1453165_at chr17 E5 76781 13.5 7 546 Supt3h suppressor of Ty 3 homolog (S. cerevisiae) 1434963_at chr17 B3 109115 13.5 7 547 Cenpm centromere protein M 1418184_at chr15 E2 66570 13.5 7 548 Shisa4 shisa homolog 4 (Xenopus laevis) 1438426_at chr1 E4 77552 13.5 7 549 Idh3a isocitrate dehydrogenase 3 (NAD+) alpha 1422500_at chr9 A5.3 67834 13.5 7 550 Yeats4 YEATS domain containing 4 1423105_a_at chr10 D2 64050 13.5 7 551 Fbxo46 F-box protein 46 1436601_at chr7 A3 243867 13.5 7 552 2010111I01Rik RIKEN cDNA 2010111I01 gene 1460695_a_at chr13 B3 72061 13.5 7 553 Msx2 homeobox, msh-like 2 1449559_at chr13 B1|13 32.0 cM 17702 13.5 7 554 2900092E17Rik RIKEN cDNA 2900092E17 gene 1424014_at chr7 F4 67278 13.5 7 555 Serhl serine hydrolase-like 1434145_s_at chr15 E1 68607 13.5 7 556 Gcsh glycine cleavage system protein H (aminomethyl carrier) 1432164_a_at chr8 E1 68133 13.5 7 557 Ikzf2 IKAROS family zinc finger 2 1437542_at chr1 C3 22779 13.5 7 558 Khdrbs3 KH domain containing, RNA binding, signal transduction associated 3 1453317_a_at chr15 D3|15 37.5 cM 13992 13.5 7 559 Med11 mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae) 1417739_at chr11 B3 66172 13.5 7 560 Pih1d1 PIH1 domain containing 1 1447750_x_at chr7 B4 68845 13.5 7 561 Exo1 exonuclease 1 1418026_at chr1 H4|1 97.0 cM 26909 13.5 7 562 Commd3 COMM domain containing 3 1433539_at chr2 A3|2 9.0 cM 12238 13.5 7 563 Sf3a1 splicing factor 3a, subunit 1 1419087_s_at chr11 A1 67465 13.5 7 564 Kcnmb4 /// LOC100047870 potassium large conductance calcium-activated channel, subfamily M, beta member 4 /// similar to calcium activated potassium channel beta 4 subunit 1449471_at chr10 D2 100047870 /// 58802 13.5 7 565 Tbca tubulin cofactor A 1456205_x_at chr13 D1 21371 13.5 7 566 1810048J11Rik RIKEN cDNA 1810048J11 gene 1453020_at chr12 C3 67708 13.5 7 567 Tacc3 transforming, acidic coiled-coil containing protein 3 1417450_a_at chr5 B2 21335 13.5 7 568 Grhl2 grainyhead-like 2 (Drosophila) 1427046_at chr15 C 252973 13.5 7 569 Nme3 non-metastatic cells 3, protein expressed in 1448905_at chr17 A3.3 79059 13.5 7 570 Gm11401 /// LOC638798 /// LOC677628 /// Tceb2 predicted gene 11401 /// similar to transcription elongation factor B (SIII), polypeptide 2 /// similar to transcription elongation factor B (SIII), polypeptide 2 /// transcription elongation factor B (SIII), polypeptide 2 1436949_a_at chr11 A1 /// chr17 A3.3 638798 /// 665250 /// 67673 /// 677628 13.5 7 571 Dbf4 DBF4 homolog (S. cerevisiae) 1418334_at chr5 A2 27214 13.5 7 572 Pltp phospholipid transfer protein 1456424_s_at chr2 H3|2 93.0 cM 18830 13.5 7 573 Kat2a K(lysine) acetyltransferase 2A 1422971_at chr11 D|11 61.4 cM 14534 13.5 7 574 Ldhb lactate dehydrogenase B 1434499_a_at chr6 G2|6 62.0 cM 16832 13.5 7 575 Gm7083 /// Sfrs3 predicted gene 7083 /// splicing factor, arginine/serine-rich 3 (SRp20) 1434512_x_at chr15 D1|15 /// chr17 A3.3|17 11.0 cM 20383 /// 632248 13.5 7 576 Tm2d2 TM2 domain containing 2 1438181_x_at chr8 A3 69742 13.5 7 577 Cd151 CD151 antigen 1424093_x_at chr7 F5|7 23.5 cM 12476 13.5 7 578 Bcor BCL6 interacting corepressor 1429438_at chrX A1.2 71458 13.5 7 579 Aurka aurora kinase A 1424511_at chr2 H3|2 100.0 cM 20878 13.5 7 580 Rabl4 RAB, member of RAS oncogene family-like 4 1434299_x_at chr15 E2 67042 13.5 7 581 Cdc25c cell division cycle 25 homolog C (S. pombe) 1456077_x_at chr18 B1|18 15.0 cM 12532 13.5 7 582 Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1416102_at chr15 B3.1 22631 13.5 7 583 Atxn2l ataxin 2-like 1438668_x_at chr7 F3 233871 13.5 7 584 Wdr5 WD repeat domain 5 1416581_at chr2 A3 140858 13.5 7 585 Cdk2 cyclin-dependent kinase 2 1416873_a_at chr10 D3 12566 13.5 7 586 Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) 1448319_at chr6 B1|6 13.0 cM 11677 13.5 7 587 Tia1 cytotoxic granule-associated RNA binding protein 1 1416813_at chr6 D2 21841 13.5 7 588 Zfp821 zinc finger protein 821 1426889_at chr8 D3 75871 13.5 7 589 Elp3 Elongation protein 3 homolog (S. cerevisiae) 1436762_x_at chr14 D1 74195 13.5 7 590 Drg1 developmentally regulated GTP binding protein 1 1434688_x_at chr11 A1 13494 13.5 7 591 Exosc6 exosome component 6 1435544_at chr8 E1 72544 13.5 7 592 Ppp2r2d protein phosphatase 2, regulatory subunit B, delta isoform 1420033_s_at chr7 F4|7 68.0 cM 52432 13.5 7 593 Nipsnap1 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans) 1448465_at chr11 A1 18082 13.5 7 594 Sema4d sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1420824_at chr13 B1 20354 13.5 7 595 Rpusd4 RNA pseudouridylate synthase domain containing 4 1452710_at chr9 A5.3 71989 13.5 7 596 Ktelc1 KTEL (Lys-Tyr-Glu-Leu) containing 1 1426535_at chr16 B4 224143 13.5 7 597 1500011H22Rik RIKEN cDNA 1500011H22 gene 1424192_at chr5 F 68948 13.5 7 598 Pbk PDZ binding kinase 1448627_s_at chr14 D1|14 28.0 cM 52033 13.5 7 599 5730494M16Rik RIKEN cDNA 5730494M16 gene 1459875_x_at chr18 A2 66648 13.5 7 600 Eif1 eukaryotic translation initiation factor 1 1423799_at chr11 D 20918 13.5 7 601 Rnps1 ribonucleic acid binding protein S1 1437851_x_at chr17 A3.3 19826 13.5 7 602 Kifc1 /// LOC100044746 kinesin family member C1 /// similar to Kifc1 protein 1449877_s_at chr17 A3.3 100044746 /// 16580 13.5 7 603 Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like 1424766_at chrX D 236930 13.5 7 604 2700078E11Rik RIKEN cDNA 2700078E11 gene 1451556_a_at chr19 D3 78832 13.5 7 605 Mycl1 v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) 1434777_at chr4 D2.2|4 55.0 cM 16918 13.5 7 606 Ciapin1 cytokine induced apoptosis inhibitor 1 1448140_at chr8 C5 109006 13.5 7 607 Orc2l origin recognition complex, subunit 2-like (S. cerevisiae) 1418226_at chr1 C1.3 18393 13.5 7 608 Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 1452046_a_at chr5 F-G1 19047 13.5 7 609 Wdr77 WD repeat domain 77 1422844_a_at chr3 F2.2 70465 13.5 7 610 Zc3hc1 zinc finger, C3HC type 1 1426654_at chr6 A3.3 232679 13.5 7 611 Med22 mediator complex subunit 22 1421528_a_at chr2 A3|2 15.5 cM 20933 13.5 7 612 Slc44a2 solute carrier family 44, member 2 1438559_x_at chr9 A3 68682 13.5 7 613 Zscan21 zinc finger and SCAN domain containing 21 1420095_s_at chr5 G2|5 78.0 cM 22697 13.5 7 614

PAGE 8

Gpr177 G protein-coupled receptor 177 1423824_at chr3 H4 68151 13.5 7 615 Kif2c kinesin family member 2C 1437611_x_at chr4 D1 73804 13.5 7 616 Grwd1 glutamate-rich WD repeat containing 1 1452171_at chr7 B4 101612 13.5 7 617 Lmnb1 lamin B1 1423520_at chr18 D3|18 29.0 cM 16906 13.5 7 618 5730494M16Rik RIKEN cDNA 5730494M16 gene 1428189_at chr18 A2 66648 13.5 7 619 Dcps decapping enzyme, scavenger 1424080_at chr9 A4 69305 13.5 7 620 Usp39 ubiquitin specific peptidase 39 1437007_x_at chr6 C1|6 31.5 cM 28035 13.5 7 621 Gm5806 /// Gm9855 /// Tdg predicted gene 5806 /// predicted gene 9855 /// thymine DNA glycosylase 1435715_x_at chr10 B2 /// chr10 C1|10 43.0 cM /// chr15 E1 21665 /// 545124 /// 624784 13.5 7 622 Ubac2 ubiquitin associated domain containing 2 1423928_at chr14 E5 68889 13.5 7 623 Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 1448151_at chr8 A1.1|8 1.0 cM 15568 13.5 7 624 Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon 1433886_at chr16 A3 224045 13.5 7 625 Gpr177 G protein-coupled receptor 177 1437434_a_at chr3 H4 68151 13.5 7 626 Fxyd7 FXYD domain-containing ion transport regulator 7 1419200_at chr7 B1 57780 13.5 8 627 Vamp3 vesicle-associated membrane protein 3 1433693_x_at chr4 E1 22319 13.5 8 628 Crygb crystallin, gamma B 1427264_at chr1 C2|1 32.0 cM 12965 13.5 8 629 Ssbp2 single-stranded DNA binding protein 2 1429951_at chr13 C3 66970 13.5 8 630 Trps1 trichorhinophalangeal syndrome I (human) 1457445_at chr15 C|15 30.1 cM 83925 13.5 8 631 ----1458241_at ----13.5 8 632 ----1439233_at ----13.5 8 633 ----1442056_at ----13.5 8 634 ----1444349_at ----13.5 8 635 ----1444787_at ----13.5 8 636 Pus3 pseudouridine synthase 3 1433104_at chr9 A5.3 67049 13.5 8 637 Dusp9 dual specificity phosphatase 9 1433844_a_at chrX B 75590 13.5 8 638 ----1459512_at ----13.5 8 639 Tbx3 T-box 3 1445757_at chr5 F|5 65.0 cM 21386 13.5 8 640 4930556N13Rik RIKEN cDNA 4930556N13 gene 1432364_at --75285 13.5 8 641 ----1458746_at ----13.5 8 642 Rpl12 ribosomal protein L12 1435655_at chr2 B 269261 13.5 8 643 Tra2a Transformer 2 alpha homolog (Drosophila) 1439043_at chr6 B2.3 101214 13.5 8 644 ----1447691_x_at ----13.5 8 645 ----1441415_at ----13.5 8 646 ----1459301_at ----13.5 8 647 Wdr75 WD repeat domain 75 1442296_at chr1 C1 73674 13.5 8 648 ----1458947_at ----13.5 8 649 Ppt1 palmitoyl-protein thioesterase 1 1420015_s_at chr4 D1-D3|4 59.1 cM 19063 13.5 8 650 ----1442479_at ----13.5 8 651 ----1441597_at ----13.5 8 652 6720477C19Rik RIKEN cDNA 6720477C19 gene 1433184_at --77731 13.5 8 653 A730041O05Rik RIKEN cDNA A730041O05 gene 1459012_at --320330 13.5 8 654 Tbrg3 transforming growth factor beta regulated gene 3 1456671_at chr15 E1 21378 13.5 8 655 Erbb2ip Erbb2 interacting protein 1439080_at chr13 D1 59079 13.5 8 656 ----1458653_at ----13.5 8 657 ----1426173_at ----13.5 8 658 Setd1a SET domain containing 1A 1450336_at chr7 F3 233904 13.5 8 659 Cux1 Cut-like homeobox 1 1441956_s_at chr5 G2|5 78.0 cM 13047 13.5 8 660 Neil3 nei like 3 (E. coli) 1440633_at chr8 B1.3 234258 13.5 8 661 ----1441679_at ----13.5 8 662 Sltm SAFB-like, transcription modulator 1443426_at chr9 D 66660 13.5 8 663 Tmem213 transmembrane protein 213 1453480_at chr6 B1 77522 13.5 8 664 Kcnn4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 1421038_a_at chr7 A3 16534 13.5 8 665 ----1445965_at ----13.5 8 666 Ocrl oculocerebrorenal syndrome of Lowe 1457313_at chrX A4 320634 13.5 8 667 Agk acylglycerol kinase 1430496_at chr6 B1 69923 13.5 8 668 Psmg4 proteasome (prosome, macropain) assembly chaperone 4 1445700_at chr13 A3.3 69666 13.5 8 669 Rif1 Rap1 interacting factor 1 homolog (yeast) 1438516_at chr2 C1.1|2 31.0 cM 51869 13.5 8 670 Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 1440609_at --26921 13.5 8 671 ----1446289_at ----13.5 8 672 ----1459844_at ----13.5 8 673 Gabrp gamma-aminobutyric acid (GABA) A receptor, pi 1424647_at chr11 A4 216643 13.5 8 674 Phf6 PHD finger protein 6 1430415_at chrX A4 70998 13.5 8 675 Ncapd3 non-SMC condensin II complex, subunit D3 1430782_at chr9 A4 78658 13.5 8 676 ----1441052_at ----13.5 8 677 Smc6 structural maintenance of chromosomes 6 1460069_at chr12 A2 67241 13.5 8 678 Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H 1457639_at chr1 A1 108664 13.5 8 679 D630029K05Rik RIKEN cDNA D630029K05 gene 1435570_s_at chr10 D2 103175 13.5 8 680 Zfp40 Zinc finger protein 40 1435984_at chr17 A3.3|17 10.05 cM 22700 13.5 8 681 Hist1h2bp histone cluster 1, H2bp 1427762_x_at chr13 A3.1 319188 13.5 8 682 Ccdc88a coiled coil domain containing 88A 1445440_at chr11 A3.3 108686 13.5 8 683 Sox9 SRY-box containing gene 9 1433889_at chr11 E2|11 69.5 cM 20682 13.5 8 684 ----1440701_at ----13.5 8 685 5830411K21Rik RIKEN cDNA 5830411K21 gene 1430379_at --78822 13.5 8 686 ----1446963_at ----13.5 8 687 Ext1 exostoses (multiple) 1 1458054_at chr15 C|15 26.55 cM 14042 13.5 8 688 Api5 apoptosis inhibitor 5 1437053_x_at chr2 E1 11800 13.5 8 689 Mrpl15 Mitochondrial ribosomal protein L15 1439988_at chr1 A1 27395 13.5 8 690 ----1446278_at ----13.5 8 691 Odz2 odd Oz/ten-m homolog 2 (Drosophila) 1454424_at chr11 A4|11 18.0 cM 23964 13.5 8 692 Spag9 sperm associated antigen 9 1437676_at chr11 C 70834 13.5 8 693 ----1459566_at ----13.5 8 694 Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 1441417_at chr9 A4|9 20.0 cM 16430 13.5 8 695 ----1447204_at ----13.5 8 696 ----1459707_at ----13.5 8 697 Lix1 limb expression 1 homolog (chicken) 1421180_at chr17 A3.1 66643 13.5 9 698 Trpc2 transient receptor potential cation channel, subfamily C, member 2 1430485_at chr7 F1|7 50.0 cM 22064 13.5 9 699 Lcorl Ligand dependent nuclear receptor corepressor-like 1458352_at chr5 B3 209707 13.5 9 700 Ube2d2 ubiquitin-conjugating enzyme E2D 2 1445885_at chr18 B2 56550 13.5 9 701 ----1458974_at ----13.5 9 702

PAGE 9

4930507A01Rik RIKEN cDNA 4930507A01 gene 1429904_at --75867 13.5 9 703 6720427H10Rik RIKEN cDNA 6720427H10 gene 1431118_at --77884 13.5 9 704 Reg3d regenerating islet-derived 3 delta 1424009_at chr6 C3 30053 13.5 9 705 Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 1440464_at chr8 A1.1|8 1.0 cM 15568 13.5 9 706 Gnb2l1 Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 1440120_at chr11 B1.2 14694 13.5 9 707 Mapk8 mitogen-activated protein kinase 8 1437045_at chr14 B 26419 13.5 9 708 D15Wsu126e DNA segment, Chr 15, Wayne State University 126, expressed 1446972_at chr15 30.0 cM 28112 13.5 9 709 Ccdc76 coiled-coil domain containing 76 1453824_at chr3 G1 229780 13.5 9 710 E330024J20Rik RIKEN cDNA E330024J20 gene 1445743_at --320654 13.5 9 711 LOC435565 interferon-inducible GTPase-like 1425722_at chr18 D3 435565 13.5 9 712 ----1439174_at ----13.5 9 713 Nxf1 Nuclear RNA export factor 1 homolog (S. cerevisiae) 1439092_at chr19 A|19 5.0 cM 53319 13.5 9 714 Tmem186 transmembrane protein 186 1439726_at chr16 A1 66690 13.5 9 715 ----1442150_at ----13.5 9 716 Tmem178 transmembrane protein 178 1429175_at chr17 E3 68027 13.5 9 717 Ep400 E1A binding protein p400 1440751_at chr5 F 75560 13.5 9 718 Prei4 preimplantation protein 4 1437953_at chr2 F3|2 74182 13.5 9 719 Tra2b transformer 2 beta homolog (Drosophila) 1441466_at chr16 B1 20462 13.5 9 720 ----1459493_at ----13.5 9 721 Dnajc1 DnaJ (Hsp40) homolog, subfamily C, member 1 1447649_x_at chr2 A2 13418 13.5 9 722 Usmg5 upregulated during skeletal muscle growth 5 1448179_at chr19 D2 66477 13.5 9 723 H3f3b H3 histone, family 3B 1430357_at chr11 E2 15081 13.5 9 724 ----1442671_at ----13.5 9 725 ----1445689_at ----13.5 9 726 Tcf4 Transcription factor 4 1458201_at --21413 13.5 9 727 4931431B13Rik RIKEN cDNA 4931431B13 gene 1430416_at --70973 13.5 9 728 Taf15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1438130_at chr11 B5 70439 13.5 9 729 ----1446107_at ----13.5 9 730 BC002199 cDNA sequence BC002199 1446235_at chr3 G2 211556 13.5 9 731 Nono non-POU-domain-containing, octamer binding protein 1431239_at chrX D 53610 13.5 9 732 Rnps1 ribonucleic acid binding protein S1 1437359_at chr17 A3.3 19826 13.5 9 733 Mbtd1 mbt domain containing 1 1441100_at chr11 D 103537 13.5 9 734 Matr3 matrin 3 1458508_at chr18 C|18 15.0 cM 17184 13.5 9 735 Gprin1 G protein-regulated inducer of neurite outgrowth 1 1424137_at chr13 B2 26913 13.5 9 736 LOC100044751 /// Zfp207 hypothetical protein LOC100044751 /// zinc finger protein 207 1434752_at chr11 B5 100044751 /// 22680 13.5 9 737 ----1439651_at ----13.5 9 738 Tle3 transducin-like enhancer of split 3, homolog of Drosophila E(spl) 1458512_at --21887 13.5 9 739 Nisch nischarin 1430151_at chr14 B 64652 13.5 9 740 ----1443337_at ----13.5 9 741 Nasp nuclear autoantigenic sperm protein (histone-binding) 1444583_at chr4 56.5 cM 50927 13.5 9 742 ----1447175_at ----13.5 9 743 Tle4 transducin-like enhancer of split 4, homolog of Drosophila E(spl) 1430384_at chr19 A|19 7.0 cM 21888 13.5 9 744 Gm550 predicted gene 550 1456549_at chr19 A 225852 13.5 9 745 1110007A13Rik RIKEN cDNA 1110007A13 gene 1439126_at chr7 F3 210711 13.5 9 746 Fubp1 far upstream element (FUSE) binding protein 1 1437543_at chr3 H3|3 70.5 cM 51886 13.5 9 747 Nfat5 Nuclear factor of activated T-cells 5 1439805_at chr8 D2|8 53.0 cM 54446 13.5 9 748 Golim4 golgi integral membrane protein 4 1459045_at chr3 E3 73124 13.5 9 749 Meis2 Meis homeobox 2 1440091_at chr2 E4-E5|2 64.0 cM 17536 13.5 9 750 ----1460032_at ----13.5 9 751 Ints6 integrator complex subunit 6 1443128_at chr14 C3 18130 13.5 9 752 ----1445166_at ----13.5 9 753 ----1439136_at ----13.5 9 754 Zmat2 zinc finger, matrin type 2 1446079_at chr18 B2 66492 13.5 9 755 ----1458575_at ----13.5 9 756 ----1443394_at ----13.5 9 757 Stox2 storkhead box 2 1441953_at chr8 B1.1 71069 13.5 9 758 ----1446946_at ----13.5 9 759 ----1446953_at ----13.5 9 760 Map2k7 mitogen-activated protein kinase kinase 7 1421416_at chr8 A1.1 26400 13.5 9 761 ----1441869_x_at ----13.5 9 762 ----1427820_at ----13.5 9 763 Fgd3 FYVE, RhoGEF and PH domain containing 3 1433398_at chr13 A5|13 31.0 cM 30938 13.5 9 764 Hist1h3f histone cluster 1, H3f 1431231_at chr13 A2-A3|13 12.0 cM 260423 13.5 9 765 9230108I15Rik RIKEN cDNA 9230108I15 gene 1438299_at chr2 H4 78078 13.5 9 766 ----1441498_at ----13.5 9 767 Csnk2a1 casein kinase 2, alpha 1 polypeptide 1453427_at chr2 G3 12995 13.5 9 768 Ttc3 tetratricopeptide repeat domain 3 1441684_at chr16 C3.3-4|16 67.9 cM 22129 13.5 9 769 Slc20a2 Solute carrier family 20, member 2 1457302_at chr8 A2|8 9.0 cM 20516 13.5 9 770 ----1443056_at ----13.5 9 771 ----1447951_at ----13.5 9 772 ----1443075_at ----13.5 9 773 MGC7817 hypothetical protein LOC620031 1425424_at chr6 G2 620031 13.5 9 774 Erbb2ip Erbb2 interacting protein 1439079_a_at chr13 D1 59079 13.5 9 775 ----1446627_at ----13.5 9 776 LOC553096 hypothetical LOC553096 1442320_at --553096 13.5 9 777 C78692 expressed sequence C78692 1446288_at --97148 13.5 9 778 ----1447312_at ----13.5 9 779 Luc7l2 LUC7-like 2 (S. cerevisiae) 1436767_at chr6 B1 192196 13.5 9 780 A130064L14Rik RIKEN cDNA A130064L14 gene 1444343_at --320257 13.5 9 781 Fus fusion, derived from t(12;16) malignant liposarcoma (human) 1455831_at chr7 F3 233908 13.5 9 782 Ube2j2 ubiquitin-conjugating enzyme E2, J2 homolog (yeast) 1430317_at chr4 E2|4 83.0 cM 140499 13.5 9 783 5930433N17Rik RIKEN cDNA 5930433N17 gene 1440721_at --399623 13.5 9 784 1810029B16Rik RIKEN cDNA 1810029B16 gene 1431117_x_at chr8 B3.3 66282 13.5 9 785 Meis1 Meis homeobox 1 1443260_at chr11 A3.1|11 11.0 cM 17268 13.5 9 786 Usp7 ubiquitin specific peptidase 7 1438249_at chr16 A1 252870 13.5 9 787 Tmtc2 transmembrane and tetratricopeptide repeat containing 2 1441033_at chr10 D1 278279 13.5 9 788 ----1456553_at ----13.5 9 789 Ccdc38 coiled-coil domain containing 38 1438569_at chr10 C2 237465 13.5 9 790

PAGE 10

----1458495_at ----13.5 9 791 ----1439191_at ----13.5 9 792 Amn1 Antagonist of mitotic exit network 1 homolog (S. cerevisiae) 1441141_at chr6 G3 232566 13.5 9 793 Dnm3os dynamin 3, opposite strand 1452382_at chr1 H2.1 474332 13.5 9 794 C80998 expressed sequence C80998 1456050_at --97819 13.5 9 795 ----1457971_at ----13.5 9 796 Top1 topoisomerase (DNA) I 1438495_at chr2 H2-3|2 92.0 cM 21969 13.5 9 797 Senp6 SUMO/sentrin specific peptidase 6 1445387_at chr9 E1 215351 13.5 9 798 Mycbp2 MYC binding protein 2 1442858_at chr14 E2.3|14 54.58 cM 105689 13.5 9 799 Rock1 Rho-associated coiled-coil containing protein kinase 1 1441162_at chr18 A2 19877 13.5 9 800 9930017N22Rik RIKEN cDNA 9930017N22 gene 1456758_at --320403 13.5 9 801 ----1444705_at ----13.5 9 802 ----1457529_x_at ----13.5 9 803 Cblb Casitas B-lineage lymphoma b 1458469_at chr16 B5 208650 13.5 9 804 Gm9840 /// Rbx1 predicted gene 9840 /// ring-box 1 1438623_x_at chr15 E1 /// chr17 B1|17 100043674 /// 56438 13.5 9 805 ----1441172_at ----13.5 9 806 ----1441248_at ----13.5 9 807 Mbtd1 Mbt domain containing 1 1443862_at chr11 D 103537 13.5 9 808 Abce1 ATP-binding cassette, sub-family E (OABP), member 1 1442071_at chr8 C 24015 13.5 9 809 Polb polymerase (DNA directed), beta 1439840_at chr8 A2|8 8.0 cM 18970 13.5 9 810 Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 1441536_at --208715 13.5 9 811 Gemin8 Gem (nuclear organelle) associated protein 8 1444239_at chrX F5 237221 13.5 9 812 Cd82 CD82 antigen 1449611_at chr2 E1|2 49.6 cM 12521 13.5 9 813 Frem2 Fras1 related extracellular matrix protein 2 1457038_at chr3 C 242022 13.5 9 814 Dpf2 D4, zinc and double PHD fingers family 2 1429903_at chr19 A|19 2.0 cM 19708 13.5 9 815 Saps3 SAPS domain family, member 3 1439161_at chr19 A 52036 13.5 9 816 ----1440011_at ----13.5 9 817 Bcl9 B-cell CLL/lymphoma 9 1455565_at chr3 F2 77578 13.5 9 818 Robo2 roundabout homolog 2 (Drosophila) 1458229_at chr16 C3.1 268902 13.5 9 819 ----1438301_at ----13.5 9 820 ----1437162_at ----13.5 9 821 ----1444762_at ----13.5 9 822 Myst2 MYST histone acetyltransferase 2 1447631_at chr11 D 217127 13.5 9 823 Ube2b ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae) 1439477_at chr11 B1.3 22210 13.5 9 824 Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 1447808_s_at chr16 B3 57738 13.5 9 825 Trpm7 transient receptor potential cation channel, subfamily M, member 7 1431355_s_at chr2 F2 58800 13.5 9 826 ----1445518_at ----13.5 9 827 Palld palladin, cytoskeletal associated protein 1440635_at chr8 B3.3 72333 13.5 9 828 Fam168a Family with sequence similarity 168, member A 1444119_at chr7 E3 319604 13.5 9 829 ----1457483_at ----13.5 9 830 ----1457842_at ----13.5 9 831 ----1438245_at ----13.5 9 832 A630007B06Rik RIKEN cDNA A630007B06 gene 1444371_at chr19 D2 213993 13.5 9 833 ----1459715_at ----13.5 9 834 Tet2 Tet oncogene family member 2 1438781_at chr3 G3 214133 13.5 9 835 ----1445933_at ----13.5 9 836 Cbara1 calcium binding atopy-related autoantigen 1 1439501_at chr10 B4 216001 13.5 9 837 Dlx2 distal-less homeobox 2 1448877_at chr2 C2|2 44.0 cM 13392 13.5 9 838 ----1446955_at ----13.5 9 839 ----1439572_at ----13.5 9 840 ----1442886_at ----13.5 9 841 3222401L13Rik RIKEN cDNA 3222401L13 gene 1458446_at chr18 B3 320513 13.5 9 842 ----1447109_at ----13.5 9 843 ----1441397_at ----13.5 9 844 6430537I21Rik RIKEN cDNA 6430537I21 gene 1441688_at --319654 13.5 9 845 Tmtc3 Transmembrane and tetratricopeptide repeat containing 3 1457294_at chr10 D1 237500 13.5 9 846 LOC552876 hypothetical LOC552876 1442041_at --552876 13.5 9 847 ----1446048_at ----13.5 9 848 Prpmp5 proline-rich protein MP5 1421490_at chr6 G1 381832 13.5 10 849 Rps9 ribosomal protein S9 1426958_at chr7 A1 76846 13.5 10 850 4930448K20Rik glyceraldehyde-3-phosphate dehydrogenase pseudogene 1433082_at chr4 A1 74662 13.5 10 851 Ednra endothelin receptor type A 1440093_at --13617 13.5 10 852 ----1445377_at ----13.5 10 853 ----1459289_at ----13.5 10 854 ----1443037_at ----13.5 10 855 ----1443534_at ----13.5 10 856 Tsc22d1 TSC22 domain family, member 1 1447360_at chr14 D3|14 42.0 cM 21807 13.5 10 857 D13Ertd787e DNA segment, Chr 13, ERATO Doi 787, expressed 1457304_at chr13 29.0 cM 52680 13.5 10 858 1810033B17Rik RIKEN cDNA 1810033B17 gene 1430612_at chr8 A1|8 0.38 cM 69189 13.5 10 859 ----1458747_at ----13.5 10 860 Gmcl1 germ cell-less homolog 1 (Drosophila) 1438888_at chr6 D1|6 47.3 cM 23885 13.5 10 861 ----1443201_at ----13.5 10 862 ----1446860_at ----13.5 10 863 Ube2w ubiquitin-conjugating enzyme E2W (putative) 1443188_at chr1 A3 66799 13.5 10 864 D9Wsu74e DNA segment, Chr 9, Wayne State University 74, expressed 1457742_at chr9 29.0 cM 27963 13.5 10 865 Airn antisense Igf2r RNA 1446095_at chr17 A1|17 7.36 cM 104103 13.5 10 866 2410018L13Rik RIKEN cDNA 2410018L13 gene 1431317_at chr12 A1.3 69732 13.5 10 867 Btf3 /// Gm7973 /// Gm9308 basic transcription factor 3 /// predicted gene 7973 /// predicted gene 9308 1433863_at chr13 D1 /// chr14 E5 /// chrX F1 218490 /// 666196 /// 668700 13.5 10 868 D130009B15Rik RIKEN cDNA D130009B15 gene 1443269_at --399631 13.5 10 869 ----1459635_at ----13.5 10 870 ----1444043_at ----13.5 10 871 Gas7 Growth arrest specific 7 1457948_at chr11 B3 14457 13.5 10 872 B230208H17Rik RIKEN cDNA B230208H17 gene 1438100_at chr2 A3 227624 13.5 10 873 ----1459008_at ----13.5 10 874 4930518F22Rik RIKEN cDNA 4930518F22 gene 1458063_at --71655 13.5 10 875 ----1436398_at ----13.5 10 876 Hbb-y hemoglobin Y, beta-like embryonic chain 1436823_x_at chr7 E3|7 49.95 cM 15135 13.5 10 877 Hbb-y hemoglobin Y, beta-like embryonic chain 1436717_x_at chr7 E3|7 49.95 cM 15135 13.5 10 878

PAGE 11

----1442411_at ----13.5 10 879 Fras1 Fraser syndrome 1 homolog (human) 1440765_at chr5 E3 231470 13.5 10 880 4933401J01Rik RIKEN cDNA 4933401J01 gene 1454564_at --71042 13.5 10 881 ----1447891_at ----13.5 10 882 Hbb-bh1 hemoglobin Z, beta-like embryonic chain 1437990_x_at chr7 E3|7 49.96 cM 15132 13.5 10 883 ----1443151_at ----13.5 10 884 ----1458290_at ----13.5 10 885 Trim31 tripartite motif-containing 31 1425308_at chr17 B1 224762 13.5 10 886 AI451458 expressed sequence AI451458 1442122_at --102916 13.5 10 887 Vti1a vesicle transport through interaction with t-SNAREs homolog 1A (yeast) 1446365_at chr19 D2 53611 13.5 10 888 AW551984 expressed sequence AW551984 1447300_at chr9 A5.1 244810 13.5 10 889 9430012M22Rik RIKEN cDNA 9430012M22 gene 1454592_at --77244 13.5 10 890 2810040C05Rik RIKEN cDNA 2810040C05 gene 1430749_at --72719 13.5 10 891 3110048L19Rik zinc finger pseudogene 1454402_at chr17 A3.2 73233 13.5 10 892 Phf21a PHD finger protein 21A 1441145_at chr2 E1 192285 13.5 10 893 ----1438960_at ----13.5 10 894 B430316J06Rik RIKEN cDNA B430316J06 gene 1439933_at --402749 13.5 10 895 ----1439175_at ----13.5 10 896 C130068B02Rik RIKEN cDNA C130068B02 gene 1440317_at --402752 13.5 10 897 Tpp2 tripeptidyl peptidase II 1430576_at chr1 C1.1|1 27.0 cM 22019 13.5 10 898 2810416A17Rik RIKEN cDNA 2810416A17 gene 1433266_at --70241 13.5 10 899 Dtl denticleless homolog (Drosophila) 1439520_at chr1 H6 76843 13.5 10 900 Gsk3b glycogen synthase kinase 3 beta 1439931_at chr16 B4 56637 13.5 10 901 ----1446167_at ----13.5 10 902 ----1446736_at ----13.5 10 903 ----1447227_at ----13.5 10 904 ----1457402_at ----13.5 10 905 Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1437775_at chr12 D3 78920 13.5 10 906 ----1446656_at ----13.5 10 907 Usp24 ubiquitin specific peptidase 24 1441018_at chr4 C7 329908 13.5 10 908 C77626 expressed sequence C77626 1444972_at --98010 13.5 10 909 5330403D14Rik RIKEN cDNA 5330403D14 gene 1453395_at --76675 13.5 10 910 ----1441612_at ----13.5 10 911 ----1445600_at ----13.5 10 912 ----1446859_at ----13.5 10 913 ----1442381_at ----13.5 10 914 Top1 topoisomerase (DNA) I 1457573_at chr2 H2-3|2 92.0 cM 21969 13.5 10 915 ----1447147_at ----13.5 10 916 1500032P08Rik RIKEN cDNA 1500032P08 gene 1447537_at --69025 13.5 10 917 ----1459571_at ----13.5 10 918 Nol11 nucleolar protein 11 1439166_at chr11 E1 68979 13.5 10 919 ----1444114_at ----13.5 10 920 AU021025 expressed sequence AU021025 1439895_at --105285 13.5 10 921 Cdc42bpa CDC42 binding protein kinase alpha 1442260_at chr1 H4 226751 13.5 10 922 ----1443533_at ----13.5 10 923 ----1443675_at ----13.5 10 924 9930033D15Rik RIKEN cDNA 9930033D15 gene 1444775_at --320147 13.5 10 925 Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex 1448716_at chr11 A4|11 16.0 cM 15126 13.5 10 926 Gabrp gamma-aminobutyric acid (GABA) A receptor, pi 1451424_at chr11 A4 216643 13.5 10 927 ----1432653_at ----13.5 10 928 Hbb-bh1 hemoglobin Z, beta-like embryonic chain 1450736_a_at chr7 E3|7 49.96 cM 15132 13.5 10 929 ----1441854_at ----13.5 10 930 ----1444326_at ----13.5 10 931 A230101C19Rik RIKEN cDNA A230101C19 gene 1432803_at --77756 13.5 10 932 ----1443514_at ----13.5 10 933 ----1444140_at ----13.5 10 934 ----1446713_at ----13.5 10 935 Hbb-bh1 hemoglobin Z, beta-like embryonic chain 1437810_a_at chr7 E3|7 49.96 cM 15132 13.5 10 936 AI465300 expressed sequence AI465300 1443972_at --102533 13.5 10 937 Slc4a8 Solute carrier family 4 (anion exchanger), member 8 1456519_at chr15 F3 59033 13.5 10 938 ----1457122_at ----13.5 10 939 ----1445512_at ----13.5 10 940 Hbb-y hemoglobin Y, beta-like embryonic chain 1450621_a_at chr7 E3|7 49.95 cM 15135 13.5 10 941 9530006C21Rik RIKEN cDNA 9530006C21 gene 1441779_at --77393 13.5 10 942 ----1446006_at ----13.5 10 943 Cluster Number and Cluster Order corresponds to Figure 3-7, male at E13.5 versus male at E15.5 dendrogram.





PAGE 1

Gene Symbol Gene Title Probe Set ID Chromosomal Location Entrez Gene Stage Enriched Cluster Number* Cluster Order* Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1 1415671_at chr8 D3 11972 15.5 1 1 1190002N15Rik /// LOC100044725 RIKEN cDNA 1190002N15 gene /// hypothetical protein LOC100044725 1433582_at chr9 E3.3 100044725 /// 68861 15.5 1 2 Mier3 mesoderm induction early response 1, family member 3 1460614_at chr13 D2.2 218613 15.5 1 3 Tmem77 transmembrane protein 77 1424782_at chr3 F3 67171 15.5 1 4 Lphn3 latrophilin 3 1439313_at chr5 D-E1 319387 15.5 1 5 Rmnd5a required for meiotic nuclear division 5 homolog A (S. cerevisiae) 1426884_at chr6 C1 68477 15.5 1 6 Gata2 GATA binding protein 2 1450333_a_at chr6 D1|6 38.5 cM 14461 15.5 1 7 Jarid2 jumonji, AT rich interactive domain 2 1422697_s_at chr13 A5|13 27.0 cM 16468 15.5 1 8 Trim2 tripartite motif-containing 2 1459860_x_at chr3 F1 80890 15.5 1 9 Lrrc16a leucine rich repeat containing 16A 1451804_a_at chr13 A3.2 68732 15.5 1 10 Ide insulin degrading enzyme 1435140_at chr19 C2|19 25.0 cM 15925 15.5 1 11 Zdhhc20 zinc finger, DHHC domain containing 20 1434236_at chr14 C3 75965 15.5 1 12 Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 1451114_at chr9 F3 67213 15.5 1 13 Kdm4a lysine (K)-specific demethylase 4A 1435340_at chr4 D2.1|4 56.5 cM 230674 15.5 1 14 Mfn2 mitofusin 2 1448131_at chr4 E2 170731 15.5 1 15 Fxr1 fragile X mental retardation gene 1, autosomal homolog 1417598_a_at chr3 B 14359 15.5 1 16 Abi1 abl-interactor 1 1423177_a_at chr2 A3|2 15.0 cM 11308 15.5 1 17 Mak10 MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae) 1433570_s_at chr13 B3 78689 15.5 1 18 1110029L17Rik RIKEN cDNA 1110029L17 gene 1455294_at --68722 15.5 1 19 Mapk13 mitogen-activated protein kinase 13 1448871_at chr17 A3-B 26415 15.5 1 20 LOC100047601 /// Nus1 similar to DNA segment, Chr 10, ERATO Doi 438, expressed 1419914_s_at chr10 B3|10 29.0 cM 100047601 /// 52014 15.5 1 21 Epha1 Eph receptor A1 1422917_at chr6 B2.1 13835 15.5 1 22 LOC100047601 /// Nus1 similar to DNA segment, Chr 10, ERATO Doi 438, expressed 1460563_at chr10 B3|10 29.0 cM 100047601 /// 52014 15.5 1 23 Rab24 RAB24, member RAS oncogene family 1421872_at chr13 B1|13 36.0 cM 19336 15.5 1 24 LOC100046895 /// Qk similar to Quaking protein /// quaking 1451179_a_at chr17 A1|17 5.9 cM 100046895 /// 19317 15.5 1 25 Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 1423621_a_at chr3 E1-E3 11416 15.5 1 26 Pla2g16 phospholipase A2, group XVI 1451611_at chr19 A 225845 15.5 1 27 Psap prosaposin 1415687_a_at chr10 B4|10 35.0 cM 19156 15.5 1 28 Jag1 jagged 1 1434070_at chr2 F3|2 77.0 cM 16449 15.5 1 29 Rab7 RAB7, member RAS oncogene family 1448159_at chr6 D1|6 38.5 cM 19349 15.5 1 30 Oxr1 oxidation resistance 1 1418501_a_at chr15 D1 170719 15.5 1 31 Fbxo8 F-box protein 8 1418510_s_at chr8 B3.2 50753 15.5 1 32 Armcx3 armadillo repeat containing, X-linked 3 1424373_at chrX E3 71703 15.5 1 33 Stx4a syntaxin 4A (placental) 1451573_a_at chr7 F4 20909 15.5 1 34 Exoc4 exocyst complex component 4 1422685_at chr6 A3.3|6 12.0 cM 20336 15.5 1 35 Rab21 RAB21, member RAS oncogene family 1437741_at chr10 D1 216344 15.5 1 36 F2r coagulation factor II (thrombin) receptor 1450852_s_at chr13 D1|13 47.0 cM 14062 15.5 1 37 Zranb1 zinc finger, RAN-binding domain containing 1 1427200_at chr7 F3 360216 15.5 1 38 Ctnna1 catenin (cadherin associated protein), alpha 1 1448149_at chr18 B1|18 11.0 cM 12385 15.5 1 39 Vapa vesicle-associated membrane protein, associated protein A 1416465_a_at chr17 E1.2 30960 15.5 1 40 Epm2aip1 EPM2A (laforin) interacting protein 1 1434105_at chr9 F3 77781 15.5 1 41 H2-K1 histocompatibility 2, K1, K region 1425336_x_at chr17 B1|17 18.44 cM 14972 15.5 1 42 Ptpra protein tyrosine phosphatase, receptor type, A 1425340_a_at chr2 G|2 73.5 cM 19262 15.5 1 43 Rap2b RAP2B, member of RAS oncogene family 1417914_at chr3 E1 74012 15.5 1 44 ----1436338_at ----15.5 1 45 Eng endoglin 1417271_a_at chr2 B|2 21.4 cM 13805 15.5 1 46 Thap2 THAP domain containing, apoptosis associated protein 2 1455336_at chr10 D2 66816 15.5 1 47 Dap death-associated protein 1451112_s_at chr15 B2 223453 15.5 1 48 Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 1429430_at chr1 A1 319263 15.5 1 49 Egfr epidermal growth factor receptor 1435888_at chr11 A1-A4|11 9.0 cM 13649 15.5 1 50 Zfp354c zinc finger protein 354C 1439044_at chr11 B1.3|11 25.0 cM 30944 15.5 1 51 Rab14 RAB14, member RAS oncogene family 1419246_s_at chr2 B 68365 15.5 1 52 Ppapdc1b phosphatidic acid phosphatase type 2 domain containing 1B 1428154_s_at chr8 A3|8 71910 15.5 1 53 Vangl2 vang-like 2 (van gogh, Drosophila) 1455592_at chr1 H3|1 93.4 cM 93840 15.5 1 54 Acadvl acyl-Coenzyme A dehydrogenase, very long chain 1424184_at chr11 B2-B5|11 38.0 cM 11370 15.5 1 55 AW549877 expressed sequence AW549877 1426459_s_at chr15 A1 106064 15.5 1 56 Zdhhc17 zinc finger, DHHC domain containing 17 1434397_at chr10 D1 320150 15.5 1 57 Tspan9 tetraspanin 9 1441968_at chr6 F3 109246 15.5 1 58 Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1434069_at chr2 H3 277360 15.5 1 59 Dctn1 dynactin 1 1435414_s_at chr6 C3|6 34.9 cM 13191 15.5 1 60 Sirpa signal-regulatory protein alpha 1416985_at chr2 F3|2 73.1 cM 19261 15.5 1 61 Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 1455777_x_at chr18 D1 15488 15.5 1 62 Rtkn rhotekin 1425601_a_at chr6 C3|6 34.81 cM 20166 15.5 1 63 Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 1433926_at chr8 D3|8 50.0 cM 234663 15.5 1 64 Aebp2 AE binding protein 2 1434080_at chr6 G1 11569 15.5 1 65 Znrf2 zinc and ring finger 2 1455291_s_at chr6 B3|6 26.0 cM 387524 15.5 1 66 Dennd1a DENN/MADD domain containing 1A 1424625_a_at chr2 B 227801 15.5 1 67 Klf6 Kruppel-like factor 6 1447448_s_at chr13 A1 23849 15.5 1 68 Bms1 BMS1 homolog, ribosome assembly protein (yeast) 1433636_at chr6 F1 213895 15.5 1 69 Lamp2 lysosomal-associated membrane protein 2 1416344_at chrX A3.3|X 13.0 cM 16784 15.5 1 70 ----1438024_at ----15.5 1 71 Zfp711 zinc finger protein 711 1432750_at chrX E1 245595 15.5 1 72 Gabarapl1 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 1416418_at chr6 F3 57436 15.5 1 73 Zfp106 zinc finger protein 106 1425332_at chr2 F1|2 67.2 cM 20402 15.5 1 74 Arfip1 ADP-ribosylation factor interacting protein 1 1454916_s_at chr3 F1 99889 15.5 1 75 Igsf3 immunoglobulin superfamily, member 3 1455048_at chr3 F2.2|3 48.5 cM 78908 15.5 1 76 Mal2 mal, T-cell differentiation protein 2 1427042_at chr15 D1 105853 15.5 1 77 Nat13 N-acetyltransferase 13 1428410_at chr16 B4 72117 15.5 1 78 Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 1448578_at chr11 B3|11 44.0 cM 18472 15.5 1 79 Ncl nucleolin 1456528_x_at chr1 D|1 48.4 cM 17975 15.5 1 80 Ssb Sjogren syndrome antigen B 1416422_a_at chr2 C2|2 41.0 cM 20823 15.5 1 81 ----1442129_at ----15.5 1 82 Fam3c family with sequence similarity 3, member C 1448904_at chr6 A3.1|6 2.0 cM 27999 15.5 1 83 Esf1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1434942_at chr2 G3 66580 15.5 1 84 Rbbp6 retinoblastoma binding protein 6 1425115_at --19647 15.5 1 85 Msl2 male-specific lethal 2 homolog (Drosophila) 1429108_at chr9 E4 77853 15.5 1 86 Arhgap5 Rho GTPase activating protein 5 1450896_at chr12 C1|12 25.75 cM 11855 15.5 1 87 Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 1428936_at chr10 C3 67972 15.5 1 88 Clint1 clathrin interactor 1 1452152_at chr11 B1.1 216705 15.5 1 89 Ptpn21 protein tyrosine phosphatase, non-receptor type 21 1419055_a_at chr12 F1 24000 15.5 1 90 Tm7sf3 transmembrane 7 superfamily member 3 1452664_a_at chr6 G3 67623 15.5 1 91 Heca headcase homolog (Drosophila) 1434478_at chr10 A2-A3 380629 15.5 1 92 Mtmr6 myotubularin related protein 6 1451726_at chr14 D1 219135 15.5 1 93 Anxa4 annexin A4 1421223_a_at chr6 D1|6 38.0 cM 11746 15.5 1 94 Nelf nasal embryonic LHRH factor 1436959_x_at chr2 A3 56876 15.5 1 95 Syap1 synapse associated protein 1 1416472_at chrX F4 67043 15.5 1 96 Sike1 suppressor of IKBKE 1 1422594_at chr3 F3 66641 15.5 1 97 Appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 1426743_at chr10 C1 216190 15.5 1 98 Nebl nebulette 1438452_at chr2 A2 74103 15.5 1 99 Cnpy4 canopy 4 homolog (zebrafish) 1428325_at chr5 G2 66455 15.5 1 100 Wdr53 WD repeat domain 53 1428839_at chr16 B2 68980 15.5 1 101 Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 1437211_x_at chr9 E1 68801 15.5 1 102 Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal 1448621_a_at chr7 E3|7 51.0 cM 20597 15.5 1 103 Itm2b integral membrane protein 2B 1417999_at chr14 D3|14 32.5 cM 16432 15.5 1 104 Rbms1 RNA binding motif, single stranded interacting protein 1 1434005_at chr2 C3 56878 15.5 1 105 Differentially expressed genes in the female at E13.5 versus female at E15.5 comparison

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Dusp16 dual specificity phosphatase 16 1418401_a_at chr6 G1|6 62.0 cM 70686 15.5 1 106 4933439F18Rik RIKEN cDNA 4933439F18 gene 1438006_at chr11 B2 66771 15.5 1 107 Cyb561 cytochrome b-561 1417507_at chr11 E1|11 65.0 cM 13056 15.5 1 108 Ngly1 N-glycanase 1 1417827_at chr14 A2|14 4.0 cM 59007 15.5 1 109 D6Wsu116e DNA segment, Chr 6, Wayne State University 116, expressed 1456056_a_at chr6 F1|6 50.3 cM 28006 15.5 1 110 Etv3 ets variant gene 3 1418637_at chr3 F1 27049 15.5 1 111 Aff4 AF4/FMR2 family, member 4 1450031_at chr11 B1.3 93736 15.5 1 112 Ramp2 receptor (calcitonin) activity modifying protein 2 1418187_at chr11 D|11 61.5 cM 54409 15.5 1 113 Myl9 myosin, light polypeptide 9, regulatory 1452670_at chr2 H1 98932 15.5 1 114 Kif1c kinesin family member 1C 1424746_at chr11 B3 16562 15.5 1 115 ----1437375_at ----15.5 1 116 Il10rb interleukin 10 receptor, beta 1419455_at chr16 C3.3|16 63.11 cM 16155 15.5 1 117 Snx21 sorting nexin family member 21 1427070_at chr2 H3 101113 15.5 1 118 Swap70 SWA-70 protein 1434225_at chr7 F1|7 50.0 cM 20947 15.5 1 119 Gnaq guanine nucleotide binding protein, alpha q polypeptide 1428939_s_at chr19 A|19 9.0 cM 14682 15.5 1 120 Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 1452712_at chr2 A7.2 229279 15.5 1 121 Pdpk1 3-phosphoinositide dependent protein kinase-1 1415729_at chr17 A3.3 18607 15.5 1 122 Svil supervillin 1460694_s_at chr18 A1 225115 15.5 1 123 Nptn neuroplastin 1415821_at chr9 B 20320 15.5 1 124 Phf17 PHD finger protein 17 1452179_at chr3 B 269424 15.5 1 125 Fkbp9 FK506 binding protein 9 1423677_at chr6 B3|6 28.0 cM 27055 15.5 1 126 Ncl nucleolin 1415772_at chr1 D|1 48.4 cM 17975 15.5 1 127 Mbnl2 muscleblind-like 2 1433754_at chr14 E4 105559 15.5 1 128 Trim2 tripartite motif-containing 2 1417027_at chr3 F1 80890 15.5 1 129 Dnajc21 DnaJ (Hsp40) homolog, subfamily C, member 21 1460711_at chr15 A2 78244 15.5 1 130 Jam3 junction adhesion molecule 3 1423503_at chr9 A4 83964 15.5 1 131 Ppp2r5a protein phosphatase 2, regulatory subunit B (B56), alpha isoform 1423911_at chr1 H6 226849 15.5 1 132 Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 1435635_at chr1 A1 319263 15.5 1 133 Stim1 stromal interaction molecule 1 1448320_at chr7 E3|7 50.0 cM 20866 15.5 1 134 Sncaip synuclein, alpha interacting protein (synphilin) 1423499_at chr18 D1 67847 15.5 1 135 Mcart1 mitochondrial carrier triple repeat 1 1433816_at chr4 B1 230125 15.5 1 136 Atf2 activating transcription factor 2 1426583_at chr2 C3 11909 15.5 1 137 Otud4 OTU domain containing 4 1434468_at chr8 C3|8 36.0 cM 73945 15.5 1 138 ----1439799_at ----15.5 1 139 Smc1a structural maintenance of chromosomes 1A 1417831_at chrX F3 24061 15.5 1 140 Ptprd protein tyrosine phosphatase, receptor type, D 1429052_at chr4 C3|4 38.0 cM 19266 15.5 1 141 Zfp146 zinc finger protein 146 1422135_at chr7 B1 26465 15.5 1 142 Picalm phosphatidylinositol binding clathrin assembly protein 1451316_a_at chr7 E1|7 47.2 cM 233489 15.5 1 143 LOC100048050 /// Lphn2 similar to calcium-independent alpha-latrotoxin receptor homolog 2 /// latrophilin 2 1434111_at chr3 H3 100048050 /// 99633 15.5 1 144 Fkbp9 FK506 binding protein 9 1437687_x_at chr6 B3|6 28.0 cM 27055 15.5 1 145 Vamp4 vesicle-associated membrane protein 4 1434796_at chr1 H1|1 85.0 cM 53330 15.5 1 146 Golga2 golgi autoantigen, golgin subfamily a, 2 1448625_at chr2 B 99412 15.5 1 147 Dhx9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 1451770_s_at chr1 G3|1 77.0 cM 13211 15.5 1 148 Galntl1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 1416760_at chr12 C3 108760 15.5 1 149 Olfml3 olfactomedin-like 3 1448475_at chr3 F2.2 99543 15.5 1 150 Nr1d2 nuclear receptor subfamily 1, group D, member 2 1416958_at chr14 A2 353187 15.5 1 151 Dennd5a DENN/MADD domain containing 5A 1424015_at chr7 F1 19347 15.5 1 152 Tm9sf4 transmembrane 9 superfamily protein member 4 1423205_at chr2 H1 99237 15.5 1 153 Lonp2 lon peptidase 2, peroxisomal 1460178_at chr8 C3 66887 15.5 1 154 Elk3 ELK3, member of ETS oncogene family 1448797_at chr10 C-D1|10 51.0 cM 13713 15.5 1 155 Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1 1454959_s_at chr5 A3|5 2.0 cM 14677 15.5 1 156 Sel1l sel-1 suppressor of lin-12-like (C. elegans) 1436774_at chr12 E 20338 15.5 1 157 Prrg3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 1439549_at chrX A7.3 208748 15.5 1 158 Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 1437132_x_at chr13 A3.3-A4 18003 15.5 1 159 Atp9a ATPase, class II, type 9A 1415932_x_at --11981 15.5 1 160 Tmem109 transmembrane protein 109 1416032_at chr19 A 68539 15.5 1 161 Efnb2 ephrin B2 1419639_at chr8 A1.1|8 2.0 cM 13642 15.5 1 162 Irf2 interferon regulatory factor 2 1418265_s_at chr8 B2 16363 15.5 1 163 Tsc22d2 TSC22 domain family, member 2 1430535_at chr3 D 72033 15.5 1 164 3110073H01Rik RIKEN cDNA 3110073H01 gene 1429771_at --73201 15.5 1 165 Foxn3 forkhead box N3 1434002_at chr12 E 71375 15.5 1 166 Mboat7 membrane bound O-acyltransferase domain containing 7 1451066_at chr7 A1 77582 15.5 1 167 Polr3a polymerase (RNA) III (DNA directed) polypeptide A 1437525_a_at chr14 A3 218832 15.5 1 168 Gm6768 /// Ncoa4 predicted gene 6768 /// nuclear receptor coactivator 4 1420808_at chr12 F2 /// chr14 B 27057 /// 627557 15.5 1 169 Hexa hexosaminidase A 1449024_a_at chr9 B|9 29.0 cM 15211 15.5 1 170 Krt7 keratin 7 1423952_a_at chr15 F2|15 58.7 cM 110310 15.5 1 171 Dusp22 dual specificity phosphatase 22 1448985_at chr13 A3.2 105352 15.5 1 172 Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1 1434440_at chr5 A3|5 2.0 cM 14677 15.5 1 173 Ghr growth hormone receptor 1451501_a_at chr15 A1|15 4.6 cM 14600 15.5 1 174 Glt8d2 glycosyltransferase 8 domain containing 2 1429402_at chr10 C1 74782 15.5 1 175 Unc84b unc-84 homolog B (C. elegans) 1433832_at chr15 E1 223697 15.5 1 176 Grn granulin 1456567_x_at chr11 D|11 60.0 cM 14824 15.5 1 177 Zadh2 zinc binding alcohol dehydrogenase, domain containing 2 1451277_at chr18 E4 225791 15.5 1 178 Mtmr9 myotubularin related protein 9 1455058_at chr14 D1 210376 15.5 1 179 Pdcd6ip programmed cell death 6 interacting protein 1415937_s_at chr9 F2 18571 15.5 1 180 Tmed5 transmembrane emp24 protein transport domain containing 5 1424573_at chr5 E5 73130 15.5 1 181 3110002H16Rik RIKEN cDNA 3110002H16 gene 1456716_s_at chr18 A1 76482 15.5 1 182 Ppil4 peptidylprolyl isomerase (cyclophilin)-like 4 1424043_at chr10 A1 67418 15.5 1 183 Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform 1438011_at chr16 B3|16 22.85 cM 13026 15.5 1 184 Ube2h ubiquitin-conjugating enzyme E2H 1438971_x_at chr6 A3.3|6 6.5 cM 22214 15.5 1 185 Rnf19a ring finger protein 19A 1417508_at chr15 B3.1 30945 15.5 1 186 1110018J18Rik RIKEN cDNA 1110018J18 gene 1434441_at chr13 B3 66129 15.5 1 187 ----1420514_at ----15.5 1 188 Hspb1 heat shock protein 1 1422943_a_at chr5 G2|5 76.0 cM 15507 15.5 1 189 Jag1 jagged 1 1421106_at chr2 F3|2 77.0 cM 16449 15.5 1 190 5730409E04Rik RIKEN cDNA 5730409E04Rik gene 1457260_at chr4 D2.2 230757 15.5 1 191 Marcks myristoylated alanine rich protein kinase C substrate 1415973_at chr10 B1|10 22.0 cM 17118 15.5 1 192 Fam59a family with sequence similarity 59, member A 1436827_at chr18 A2 381126 15.5 1 193 Fam102b family with sequence similarity 102, member B 1455033_at chr3 F3 329739 15.5 1 194 Acvr1 activin A receptor, type 1 1416786_at chr2 C1.1 11477 15.5 1 195 Etv5 ets variant gene 5 1428142_at chr16 B1 104156 15.5 1 196 Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 1437735_at chr10 C|10 58.0 cM 17931 15.5 1 197 Shisa5 shisa homolog 5 (Xenopus laevis) 1437503_a_at chr9 F2 66940 15.5 1 198 Atf2 activating transcription factor 2 1452116_s_at chr2 C3 11909 15.5 1 199 Txnip thioredoxin interacting protein 1415996_at chr3 47.1 cM 56338 15.5 1 200 Trim8 tripartite motif protein 8 1418577_at chr19 D1 93679 15.5 1 201 Yipf6 Yip1 domain family, member 6 1455111_at chrX C2 77929 15.5 1 202 Fam63a family with sequence similarity 63, member A 1426655_a_at chr3 F2 75007 15.5 1 203 BC023744 cDNA sequence BC023744 1436591_at chr5 F 231668 15.5 1 204 Tpbg trophoblast glycoprotein 1423311_s_at chr9 E3.1 21983 15.5 1 205 ----1430245_at ----15.5 1 206 Usp30 ubiquitin specific peptidase 30 1436009_at chr5 F|5 61.0 cM 100756 15.5 1 207 Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 1439368_a_at chr17 A3.3 65962 15.5 1 208 Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 1451075_s_at chr10 D3|10 70.0 cM 52468 15.5 1 209 Lpar1 lysophosphatidic acid receptor 1 1417143_at chr4 B3|4 16.0 cM 14745 15.5 1 210 Neo1 neogenin 1447693_s_at chr9 B 18007 15.5 1 211 Pcsk6 proprotein convertase subtilisin/kexin type 6 1426981_at chr7 C|7 28.5 cM 18553 15.5 1 212

PAGE 3

Meis1 Meis homeobox 1 1450992_a_at chr11 A3.1|11 11.0 cM 17268 15.5 1 213 Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 1452969_at chr10 C3 67972 15.5 1 214 Fmr1 fragile X mental retardation syndrome 1 homolog 1423369_at chrX A7.1|X 24.5 cM 14265 15.5 1 215 Scp2 sterol carrier protein 2, liver 1449686_s_at chr4 C7|4 52.0 cM 20280 15.5 1 216 Megf9 multiple EGF-like-domains 9 1433968_a_at chr4 C2 230316 15.5 1 217 Srd5a3 steroid 5 alpha-reductase 3 1456691_s_at chr5 C3.3 57357 15.5 1 218 Manea mannosidase, endo-alpha 1455403_at chr4 A3 242362 15.5 1 219 Asph aspartate-beta-hydroxylase 1450058_at chr4 A1 65973 15.5 1 220 Loxl3 lysyl oxidase-like 3 1418269_at chr6 C3|6 34.76 cM 16950 15.5 1 221 Fam63a family with sequence similarity 63, member A 1438321_x_at chr3 F2 75007 15.5 1 222 Cwf19l2 CWF19-like 2, cell cycle control (S. pombe) 1456019_at chr9 A1 244672 15.5 1 223 Chst1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 1449147_at --76969 15.5 1 224 Etfdh electron transferring flavoprotein, dehydrogenase 1451084_at chr3 E3|3 31.8 cM 66841 15.5 1 225 Slc17a5 solute carrier family 17 (anion/sugar transporter), member 5 1429116_at chr9 E1 235504 15.5 1 226 Nkap NFKB activating protein 1435662_at chrX A3.3 67050 15.5 1 227 Grn granulin 1438629_x_at chr11 D|11 60.0 cM 14824 15.5 1 228 Tbc1d15 TBC1 domain family, member 15 1416060_at chr10 D2 66687 15.5 1 229 Tmem87a transmembrane protein 87A 1424454_at chr2 E5 211499 15.5 1 230 Pten phosphatase and tensin homolog 1422553_at chr19 C1|19 24.5 cM 19211 15.5 1 231 Vps37a vacuolar protein sorting 37A (yeast) 1419177_at chr8 B1.2|8 22.0 cM 52348 15.5 1 232 B930041F14Rik RIKEN cDNA B930041F14 gene 1438635_x_at chr4 E2 230991 15.5 1 233 Klhl5 kelch-like 5 (Drosophila) 1426530_a_at chr5 C3.1 71778 15.5 1 234 Trip12 thyroid hormone receptor interactor 12 1423899_at chr1 F 14897 15.5 1 235 Ppp1r9a protein phosphatase 1, regulatory (inhibitor) subunit 9A 1456072_at chr6 A1|6 0.5 cM 243725 15.5 1 236 Slc25a16 solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16 1434996_at chr10 B4 73132 15.5 1 237 Pnpla8 patatin-like phospholipase domain containing 8 1417768_at chr12 B3 67452 15.5 1 238 Tmem64 transmembrane protein 64 1433735_a_at chr4 A2 100201 15.5 1 239 Zc3h14 zinc finger CCCH type containing 14 1426999_at chr12 F1 75553 15.5 1 240 Dkk3 dickkopf homolog 3 (Xenopus laevis) 1448669_at chr7 F1 50781 15.5 1 241 Adcy6 adenylate cyclase 6 1418128_at chr15 F 11512 15.5 1 242 1110036O03Rik RIKEN cDNA 1110036O03 gene 1455288_at chr11 D 66180 15.5 1 243 Tmem168 transmembrane protein 168 1423822_a_at chr6 A2 101118 15.5 1 244 Efr3a EFR3 homolog A (S. cerevisiae) 1416131_s_at chr15 D1 76740 15.5 1 245 Hook3 hook homolog 3 (Drosophila) 1435157_at chr8 A2 320191 15.5 1 246 Synpo synaptopodin 1434089_at chr18 D3 104027 15.5 1 247 Akap11 A kinase (PRKA) anchor protein 11 1434764_at chr14 D3 219181 15.5 1 248 Rbms3 RNA binding motif, single stranded interacting protein 1436937_at chr9 F3 207181 15.5 1 249 Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1 1427510_at chr5 A3|5 2.0 cM 14677 15.5 1 250 Kif13a kinesin family member 13A 1455746_at chr13 B1 16553 15.5 1 251 Btbd10 /// LOC100047893 BTB (POZ) domain containing 10 /// similar to BTB (POZ) domain containing 10 1438578_a_at chr7 F2 100047893 /// 68815 15.5 1 252 Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 1439456_x_at chrX A1.1 70495 15.5 1 253 Arhgef18 rho/rac guanine nucleotide exchange factor (GEF) 18 1418553_at chr8 A1.1 102098 15.5 1 254 Ptprd protein tyrosine phosphatase, receptor type, D 1424886_at chr4 C3|4 38.0 cM 19266 15.5 1 255 Bicd2 bicaudal D homolog 2 (Drosophila) 1437875_at chr13 A5 76895 15.5 1 256 Serinc3 serine incorporator 3 1455550_x_at chr2 H3 26943 15.5 1 257 Slmap sarcolemma associated protein 1426457_at chr14 B 83997 15.5 1 258 Chmp2b chromatin modifying protein 2B 1428253_at chr16 C1.3 68942 15.5 1 259 Ssbp2 single-stranded DNA binding protein 2 1449815_a_at chr13 C3 66970 15.5 1 260 Tmem167b transmembrane protein 167B 1429042_at chr3 F3 67495 15.5 1 261 Polr3g polymerase (RNA) III (DNA directed) polypeptide G 1449155_at chr13 C3 67486 15.5 1 262 Smad1 MAD homolog 1 (Drosophila) 1448208_at chr8 C2 17125 15.5 1 263 Amotl1 angiomotin-like 1 1455247_at chr9 A3 75723 15.5 1 264 Ncl nucleolin 1415771_at chr1 D|1 48.4 cM 17975 15.5 1 265 Vim vimentin 1438118_x_at chr2 A2|2 7.0 cM 22352 15.5 1 266 Dcaf12 DDB1 and CUL4 associated factor 12 1438669_at chr4 B1 68970 15.5 1 267 Upf2 UPF2 regulator of nonsense transcripts homolog (yeast) 1435030_at chr2 A1 326622 15.5 1 268 Fjx1 four jointed box 1 (Drosophila) 1450728_at chr2 E2 14221 15.5 1 269 Ehd2 EH-domain containing 2 1459823_at chr7 A2|7 15.13 cM 259300 15.5 1 270 Wasf2 WAS protein family, member 2 1454673_at chr4 D2.3 242687 15.5 1 271 Snx2 sorting nexin 2 1460224_at chr18 D1 67804 15.5 1 272 Ube3a ubiquitin protein ligase E3A 1416680_at chr7 C|7 28.65 cM 22215 15.5 1 273 LOC100046998 /// Opa1 similar to optic atrophy 1 (autosomal dominant) 1434890_at chr16 B2|16 21.5 cM 100046998 /// 74143 15.5 1 274 Rxra retinoid X receptor alpha 1454773_at chr2 A3|2 17.0 cM 20181 15.5 1 275 Ctla2a /// Ctla2b cytotoxic T lymphocyte-associated protein 2 alpha 1416811_s_at chr12 C1|13 /// chr13 B2|13 36.0 cM 13024 /// 13025 15.5 1 276 Gpam glycerol-3-phosphate acyltransferase, mitochondrial 1419499_at chr19 D2|19 52.0 cM 14732 15.5 1 277 Stag2 stromal antigen 2 1421849_at --20843 15.5 1 278 Igsf3 immunoglobulin superfamily, member 3 1455049_at chr3 F2.2|3 48.5 cM 78908 15.5 1 279 Wdr26 WD repeat domain 26 1423962_at chr1 H4 226757 15.5 1 280 Mapk3 mitogen-activated protein kinase 3 1427060_at chr7 F3|7 61.0 cM 26417 15.5 1 281 Adam10 a disintegrin and metallopeptidase domain 10 1428103_at chr9 D|9 41.0 cM 11487 15.5 1 282 Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 1455159_at chr14 B 72993 15.5 1 283 Fam120a family with sequence similarity 120, member A 1427296_at chr13 A5 218236 15.5 1 284 Ptpn12 protein tyrosine phosphatase, non-receptor type 12 1450478_a_at chr5 A3-B 19248 15.5 1 285 Scamp2 secretory carrier membrane protein 2 1448404_at chr9 B 24044 15.5 1 286 Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 1436180_at chr2 H4|2 106.0 cM 13002 15.5 1 287 Klf10 Kruppel-like factor 10 1416029_at chr15 B3.1 21847 15.5 1 288 Zfp148 zinc finger protein 148 1418381_at chr16 B3|16 21.1 cM 22661 15.5 1 289 5033414K04Rik RIKEN cDNA 5033414K04 gene 1436999_at chr1 C5 98496 15.5 1 290 Rdh14 retinol dehydrogenase 14 (all-trans and 9-cis) 1417438_at chr12 A1.1 105014 15.5 1 291 Fam3c family with sequence similarity 3, member C 1417953_at chr6 A3.1|6 2.0 cM 27999 15.5 1 292 Tor1b torsin family 1, member B 1448848_at chr2 B 30934 15.5 1 293 Scarb2 scavenger receptor class B, member 2 1454704_at chr5 E3 12492 15.5 1 294 Tm9sf3 transmembrane 9 superfamily member 3 1416509_at chr19 C3 107358 15.5 1 295 Gosr2 golgi SNAP receptor complex member 2 1419371_s_at chr11 E1|11 62.0 cM 56494 15.5 1 296 Dnmt3a DNA methyltransferase 3A 1423063_at chr12 A2-A3 13435 15.5 1 297 Odz3 odd Oz/ten-m homolog 3 (Drosophila) 1449315_at chr8 B2 23965 15.5 1 298 Acbd3 acyl-Coenzyme A binding domain containing 3 1452137_at chr1 H4|1 98.7 cM 170760 15.5 1 299 Zfp445 zinc finger protein 445 1454774_at chr9 F4 235682 15.5 1 300 Zfp800 zinc finger protein 800 1456790_at chr6 A3.2 627049 15.5 1 301 Tnrc6a trinucleotide repeat containing 6a 1425036_a_at chr7 F3 233833 15.5 1 302 BC033915 cDNA sequence BC033915 1455437_at chr9 A5.2 70661 15.5 1 303 Cebpd CCAAT/enhancer binding protein (C/EBP), delta 1423233_at chr16 A2|16 9.0 cM 12609 15.5 1 304 Rock1 Rho-associated coiled-coil containing protein kinase 1 1423445_at chr18 A2 19877 15.5 1 305 Myo1c myosin IC 1419649_s_at chr11 C-E1|11 44.13 cM 17913 15.5 1 306 Dnajb4 DnaJ (Hsp40) homolog, subfamily B, member 4 1451177_at chr3 H3 67035 15.5 1 307 Tspyl3 TSPY-like 3 1447788_s_at chr2 H1 241732 15.5 1 308 Pir pirin 1429001_at chrX F5 69656 15.5 1 309 Ermp1 endoplasmic reticulum metallopeptidase 1 1433702_at chr19 C1|19 24.5 cM 226090 15.5 1 310 Usp7 ubiquitin specific peptidase 7 1454948_at chr16 A1 252870 15.5 1 311 Klf6 Kruppel-like factor 6 1433508_at chr13 A1 23849 15.5 1 312 Gulp1 GULP, engulfment adaptor PTB domain containing 1 1434423_at chr1 C1 70676 15.5 1 313 Cul3 cullin 3 1450756_s_at chr1 C4 26554 15.5 1 314 Dcun1d1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 1455053_a_at chr3 B 114893 15.5 1 315 Suox sulfite oxidase 1451339_at chr10 D3 211389 15.5 1 316 Cpne3 copine III 1435450_at chr4 A3 70568 15.5 1 317 Wdr46 WD repeat domain 46 1437828_s_at chr17 B1 57315 15.5 1 318 Add1 adducin 1 (alpha) 1450054_at chr5 B2|5 20.0 cM 11518 15.5 1 319

PAGE 4

Anxa7 annexin A7 1416138_at chr14 A3|14 2.5 cM 11750 15.5 1 320 C1galt1c1 C1GALT1-specific chaperone 1 1416655_at chrX A2 59048 15.5 1 321 Fam18b family with sequence similarity 18, member B 1452953_at chr11 B2 67510 15.5 1 322 Arf3 ADP-ribosylation factor 3 1437331_a_at chr15 F2 11842 15.5 1 323 Eprs glutamyl-prolyl-tRNA synthetase 1452157_at chr1 H4-H6 107508 15.5 1 324 Exoc4 exocyst complex component 4 1422686_s_at chr6 A3.3|6 12.0 cM 20336 15.5 1 325 Egr2 early growth response 2 1427683_at chr10 B5|10 35.0 cM 13654 15.5 1 326 LOC676870 /// Pbx1 region containing RIKEN cDNA 2310056B04 gene; pre B-cell leukemia transcription factor 1 1428646_at chr1 H2.3|1 88.1 cM 18514 /// 676870 15.5 1 327 Atp8b2 ATPase, class I, type 8B, member 2 1434026_at chr3 F2 54667 15.5 1 328 Rasa2 RAS p21 protein activator 2 1455181_at chr9 E4 114713 15.5 1 329 Vapa vesicle-associated membrane protein, associated protein A 1416466_at chr17 E1.2 30960 15.5 1 330 Rab2b RAB2B, member RAS oncogene family 1452668_x_at chr14 C2 76338 15.5 1 331 Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) 1416840_at chrX A1.2 68041 15.5 1 332 Ubxn4 UBX domain protein 4 1426486_at chr1 E4 67812 15.5 1 333 Luc7l2 LUC7-like 2 (S. cerevisiae) 1437761_at chr6 B1 192196 15.5 1 334 Sparc secreted acidic cysteine rich glycoprotein 1416589_at chr11 B1|11 29.9 cM 20692 15.5 1 335 Pvrl4 poliovirus receptor-related 4 1451690_a_at --71740 15.5 1 336 Maml1 mastermind like 1 (Drosophila) 1426769_s_at chr11 B1.3 103806 15.5 1 337 Cyth3 cytohesin 3 1418758_a_at chr5 G2|5 82.0 cM 19159 15.5 1 338 D1Ertd448e DNA segment, Chr 1, ERATO Doi 448, expressed 1455723_at chr1 17.0 cM 52318 15.5 1 339 Pxmp4 peroxisomal membrane protein 4 1422780_at chr2 H2 59038 15.5 1 340 Nek7 NIMA (never in mitosis gene a)-related expressed kinase 7 1416816_at chr1 E4|1 73.0 cM 59125 15.5 1 341 Baz2b bromodomain adjacent to zinc finger domain, 2B 1435240_at chr2 C1.1 407823 15.5 1 342 Rbbp6 retinoblastoma binding protein 6 1425114_at --19647 15.5 1 343 Usp47 ubiquitin specific peptidase 47 1426977_at chr7 F2 74996 15.5 1 344 Ggta1 glycoprotein galactosyltransferase alpha 1, 3 1418483_a_at chr2 B|2 25.0 cM 14594 15.5 1 345 Scfd1 Sec1 family domain containing 1 1428335_a_at chr12 C1 76983 15.5 1 346 Pofut2 protein O-fucosyltransferase 2 1437845_x_at chr10 C1 80294 15.5 1 347 Rab10 RAB10, member RAS oncogene family 1429296_at chr12 A1.1|12 2.0 cM 19325 15.5 1 348 Limch1 LIM and calponin homology domains 1 1435321_at chr5 C3.1 77569 15.5 1 349 Tbl1xr1 transducin (beta)-like 1X-linked receptor 1 1434839_s_at chr3 A3 81004 15.5 1 350 Ccny /// LOC100044842 cyclin Y /// similar to cyclin fold protein 1 1428971_at chr18 A1 100044842 /// 67974 15.5 1 351 D15Ertd621e DNA segment, Chr 15, ERATO Doi 621, expressed 1454705_at chr15 D1|15 33.2 cM 210998 15.5 1 352 C230096C10Rik RIKEN cDNA C230096C10 gene 1434021_at chr4 D3 230866 15.5 1 353 ----1455249_at ----15.5 1 354 Spop speckle-type POZ protein 1416524_at chr11 D|11 55.6 cM 20747 15.5 1 355 Clstn1 calsyntenin 1 1421860_at --65945 15.5 1 356 Clasp1 CLIP associating protein 1 1452265_at chr1 E2 76707 15.5 1 357 Ndnl2 necdin-like 2 1422554_at chr7 C 66647 15.5 1 358 BC059842 cDNA sequence BC059842 1440819_s_at chr4 D2.1 230676 15.5 1 359 Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 1434775_at chr8 E2 93742 15.5 1 360 Atxn7 ataxin 7 1436175_at chr14 A1 246103 15.5 1 361 Rod1 ROD1 regulator of differentiation 1 (S. pombe) 1455819_at chr4 B3 230257 15.5 1 362 Filip1l filamin A interacting protein 1-like 1428861_at chr16 C1.1 78749 15.5 1 363 Tmem30a transmembrane protein 30A 1448339_at chr9 E1 69981 15.5 1 364 Abhd5 abhydrolase domain containing 5 1417566_at chr9 F4 67469 15.5 1 365 Sfxn3 sideroflexin 3 1417893_at chr19 D1 94280 15.5 1 366 Slc39a6 solute carrier family 39 (metal ion transporter), member 6 1424674_at chr18 A2 106957 15.5 1 367 Eif4b eukaryotic translation initiation factor 4B 1426378_at chr15 F3 75705 15.5 1 368 Zbtb43 zinc finger and BTB domain containing 43 1435900_at chr2 B 71834 15.5 1 369 Zfp622 zinc finger protein 622 1425030_at chr15 B1|15 8.9 cM 52521 15.5 1 370 Ostm1 osteopetrosis associated transmembrane protein 1 1428334_at chr10 B2|10 29.0 cM 14628 15.5 1 371 Far1 fatty acyl CoA reductase 1 1426369_at chr7 F2 67420 15.5 1 372 Setx senataxin 1433794_at chr2 A3 269254 15.5 1 373 Gba glucosidase, beta, acid 1450099_a_at chr3 F1|3 44.05 cM 14466 15.5 1 374 Arid1b AT rich interactive domain 1B (SWI-like) 1455979_at chr17 A1 239985 15.5 1 375 Yipf5 Yip1 domain family, member 5 1444289_at chr18 B3 67180 15.5 1 376 BC005537 cDNA sequence BC005537 1450877_at chr13 A3.2 79555 15.5 1 377 Gas2l3 growth arrest-specific 2 like 3 1455980_a_at chr10 C2 237436 15.5 1 378 Armcx2 armadillo repeat containing, X-linked 2 1415780_a_at chrX E3 67416 15.5 1 379 Pdpk1 3-phosphoinositide dependent protein kinase-1 1416501_at chr17 A3.3 18607 15.5 1 380 Cd81 CD81 antigen 1416330_at chr7 F5|7 69.3 cM 12520 15.5 1 381 Tmem106b transmembrane protein 106B 1452290_at chr6 A2 71900 15.5 1 382 Fubp3 far upstream element (FUSE) binding protein 3 1433679_at chr2 B 320267 15.5 1 383 Stk17b serine/threonine kinase 17b (apoptosis-inducing) 1423452_at chr1 C1.1 98267 15.5 1 384 Tnfaip8 tumor necrosis factor, alpha-induced protein 8 1416950_at chr18 D1 106869 15.5 1 385 Ndrg3 N-myc downstream regulated gene 3 1417663_a_at chr2 H1 29812 15.5 1 386 Morc4 microrchidia 4 1434436_at chrX F1 75746 15.5 1 387 Gm6245 /// Ubxn2a predicted gene 6245 /// UBX domain protein 2A 1425020_at chr12 A1.1 /// chr13 A3.3 217379 /// 621629 15.5 1 388 Trim2 tripartite motif-containing 2 1448551_a_at chr3 F1 80890 15.5 1 389 Golph3 golgi phosphoprotein 3 1450394_at chr15 A1 66629 15.5 1 390 Camsap1l1 calmodulin regulated spectrin-associated protein 1-like 1 1429044_at chr1 E4 67886 15.5 1 391 Rnf13 ring finger protein 13 1451074_at chr3 D 24017 15.5 1 392 Zswim1 zinc finger, SWIM domain containing 1 1451189_at chr2 H3 71971 15.5 1 393 Gabpb2 GA repeat binding protein, beta 2 1455110_at chr3 F2 213054 15.5 1 394 Nfe2l1 nuclear factor, erythroid derived 2,-like 1 1416331_a_at chr11 D-E|11 57.0 cM 18023 15.5 1 395 Sec24d Sec24 related gene family, member D (S. cerevisiae) 1426972_at chr3 G3 69608 15.5 1 396 Sertad2 SERTA domain containing 2 1454815_at chr11 A3.2 58172 15.5 1 397 Oat ornithine aminotransferase 1416452_at chr7 F3|7 63.0 cM 18242 15.5 1 398 Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 1419883_s_at chr8 B3.3 11966 15.5 1 399 Rb1 retinoblastoma 1 1417850_at chr14 D3|14 41.0 cM 19645 15.5 1 400 Pdcd4 programmed cell death 4 1418840_at chr19 D2|19 20.0 cM 18569 15.5 1 401 Slc31a1 solute carrier family 31, member 1 1433750_at chr4 C1-C2 20529 15.5 1 402 Ubap2l ubiquitin associated protein 2-like 1435882_at chr3 F2|3 74383 15.5 1 403 Cd164 CD164 antigen 1416440_at chr10 B2|10 25.0 cM 53599 15.5 1 404 Styx serine/threonine/tyrosine interaction protein 1429710_at chr14 C1 56291 15.5 1 405 Tmem123 transmembrane protein 123 1448623_at chr9 A1 71929 15.5 1 406 Reep3 receptor accessory protein 3 1424781_at chr10 B5.1|10 30.0 cM 28193 15.5 1 407 2900026A02Rik RIKEN cDNA 2900026A02 gene 1429089_s_at chr5 F 243219 15.5 1 408 Dynll2 dynein light chain LC8-type 2 1418258_s_at chr11 C 68097 15.5 1 409 Xiap X-linked inhibitor of apoptosis 1437533_at chrX A3-A5 11798 15.5 1 410 ----1433898_at ----15.5 1 411 Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 1441894_s_at chr15 F3 56149 15.5 1 412 Snhg1 small nucleolar RNA host gene (non-protein coding) 1 1439399_a_at chr19 A 83673 15.5 1 413 Nsun3 NOL1/NOP2/Sun domain family member 3 1436735_at chr16 C1.3 106338 15.5 1 414 Pigq phosphatidylinositol glycan anchor biosynthesis, class Q 1415946_at chr17 B 14755 15.5 1 415 Sypl synaptophysin-like protein 1435081_at chr12 B2|12 15.0 cM 19027 15.5 1 416 Sppl3 signal peptide peptidase 3 1451073_at chr5 F 74585 15.5 1 417 Jak2 Janus kinase 2 1421066_at chr19 C1|19 24.0 cM 16452 15.5 1 418 Ppig peptidyl-prolyl isomerase G (cyclophilin G) 1435341_at chr2 C2 228005 15.5 1 419 Rnf11 ring finger protein 11 1426404_a_at chr4 C7 29864 15.5 1 420 Fermt2 fermitin family homolog 2 (Drosophila) 1434180_at chr14 C1 218952 15.5 1 421 Acadm acyl-Coenzyme A dehydrogenase, medium chain 1415984_at chr3 H3|3 73.6 cM 11364 15.5 1 422 Tbl2 transducin (beta)-like 2 1434224_at chr5 G2|5 63.5 cM 27368 15.5 1 423 Scamp2 secretory carrier membrane protein 2 1416611_at chr9 B 24044 15.5 1 424 BC013529 cDNA sequence BC013529 1424026_s_at chr10 A1 215751 15.5 1 425 Snhg1 small nucleolar RNA host gene (non-protein coding) 1 1433674_a_at chr19 A 83673 15.5 1 426

PAGE 5

Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 1449893_a_at chr6 D2|6 39.0 cM 16206 15.5 1 427 Ube4b ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) 1448410_at chr4 E2|4 76.4 cM 63958 15.5 1 428 Apcdd1 adenomatosis polyposis coli down-regulated 1 1437604_x_at chr18 E1 494504 15.5 1 429 Plekhh1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 1447807_s_at chr12 C3 211945 15.5 1 430 ----1448986_x_at ----15.5 1 431 Ubqln1 ubiquilin 1 1424368_s_at chr13 B1 56085 15.5 1 432 Lrrc28 leucine rich repeat containing 28 1433858_at chr7 C 67867 15.5 1 433 Haghl hydroxyacylglutathione hydrolase-like 1428584_a_at chr17 A3.3 68977 15.5 1 434 Ccdc104 coiled-coil domain containing 104 1451442_at chr11 A4 216618 15.5 1 435 Rcor3 REST corepressor 3 1428343_at chr1 H6 214742 15.5 1 436 Ube3a ubiquitin protein ligase E3A 1416682_at chr7 C|7 28.65 cM 22215 15.5 1 437 Golga4 golgi autoantigen, golgin subfamily a, 4 1417674_s_at chr9 F3 54214 15.5 1 438 Ccdc6 coiled-coil domain containing 6 1428311_at chr10 B5.3 76551 15.5 1 439 Map2k4 mitogen-activated protein kinase kinase 4 1451982_at chr11 B3|11 33.0 cM 26398 15.5 1 440 Fam122b family with sequence similarity 122, member B 1452682_at chrX A5 78755 15.5 1 441 Gmfg glia maturation factor, gamma 1419194_s_at chr7 A3 63986 15.5 1 442 Dstyk dual serine/threonine and tyrosine protein kinase 1436300_at chr1 E4 213452 15.5 1 443 Iqsec1 IQ motif and Sec7 domain 1 1427145_at chr6 D1|6 38.0 cM 232227 15.5 1 444 Fam120a family with sequence similarity 120, member A 1433572_a_at chr13 A5 218236 15.5 1 445 Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 1422508_at chr16 B4 11964 15.5 1 446 2510039O18Rik RIKEN cDNA 2510039O18 gene 1451078_at chr4 E1 77034 15.5 1 447 Abcd3 ATP-binding cassette, sub-family D (ALD), member 3 1416679_at chr3 G-H1|3 56.6 cM 19299 15.5 1 448 Hdac8 histone deacetylase 8 1428933_at chrX C3 70315 15.5 1 449 LOC100047324 /// Sesn1 similar to Sesn1 protein /// sestrin 1 1454699_at chr10 B2|10 25.0 cM 100047324 /// 140742 15.5 1 450 Rfx7 regulatory factor X, 7 1434521_at chr9 D 319758 15.5 1 451 Trim35 tripartite motif-containing 35 1454650_at chr14 D1 66854 15.5 1 452 Tmx3 thioredoxin-related transmembrane protein 3 1419925_s_at chr18 E4 67988 15.5 1 453 Nat12 N-acetyltransferase 12 1428453_at chr14 C1 70646 15.5 1 454 Trub1 TruB pseudouridine (psi) synthase homolog 1 (E. coli) 1428281_at chr19 D2 72133 15.5 1 455 Crtap cartilage associated protein 1448592_at chr9 F3-F4 56693 15.5 1 456 2610301B20Rik RIKEN cDNA 2610301B20 gene 1429451_at chr4 A1 67157 15.5 1 457 Lmo2 LIM domain only 2 1454086_a_at chr2 E2|2 60.0 cM 16909 15.5 1 458 Arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 1415711_at chr1 A2 211673 15.5 1 459 LOC100046746 /// Smap1 similar to SMAP1 /// stromal membrane-associated protein 1 1423956_at chr1 A5 100046746 /// 98366 15.5 1 460 Tm9sf1 transmembrane 9 superfamily member 1 1418198_a_at chr14 C3 74140 15.5 1 461 Copb1 coatomer protein complex, subunit beta 1 1423301_at chr7 F1|7 53.3 cM 70349 15.5 1 462 Mfsd1 major facilitator superfamily domain containing 1 1451247_at chr3 E2 66868 15.5 1 463 X99384 cDNA sequence X99384 1448134_at chr10 B4 27355 15.5 1 464 D4Ertd22e DNA segment, Chr 4, ERATO Doi 22, expressed 1454981_at chr4 D3|4 69.8 cM 213491 15.5 1 465 2310044H10Rik RIKEN cDNA 2310044H10 gene 1424038_a_at chr7 B4 69683 15.5 1 466 Slu7 SLU7 splicing factor homolog (S. cerevisiae) 1447146_s_at chr11 A5-B1.1 193116 15.5 1 467 C1d C1D nuclear receptor co-repressor 1448505_at chr11 A2 57316 15.5 1 468 Efs embryonal Fyn-associated substrate 1416716_at chr14 C3 13644 15.5 1 469 Ctsz cathepsin Z 1417870_x_at chr2 H4|2 103.5 cM 64138 15.5 1 470 Naf1 nuclear assembly factor 1 homolog (S. cerevisiae) 1452192_at chr8 B3.3 234344 15.5 1 471 Itfg1 integrin alpha FG-GAP repeat containing 1 1419041_at chr8 C4|8 39.0 cM 71927 15.5 1 472 Azi2 5-azacytidine induced gene 2 1431822_a_at chr9 F3 27215 15.5 1 473 Uba3 ubiquitin-like modifier activating enzyme 3 1417202_s_at chr6 D3 22200 15.5 1 474 Ufsp2 UFM1-specific peptidase 2 1418319_at chr8 B1.1 192169 15.5 1 475 Rraga Ras-related GTP binding A 1428905_at chr4 C4 68441 15.5 1 476 Hadh hydroxyacyl-Coenzyme A dehydrogenase 1460184_at chr3 G3 15107 15.5 1 477 Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 1416189_a_at chr6 D1 53421 15.5 1 478 Mcl1 myeloid cell leukemia sequence 1 1416880_at chr3 F2.1|3 43.6 cM 17210 15.5 1 479 Pdha1 pyruvate dehydrogenase E1 alpha 1 1418560_at chrX F3-F4|X 66.5 cM 18597 15.5 1 480 Eri1 exoribonuclease 1 1418828_at chr8 B1.1 67276 15.5 1 481 Idh3b isocitrate dehydrogenase 3 (NAD+) beta 1418886_s_at chr2 F3 170718 15.5 1 482 D030074E01Rik RIKEN cDNA D030074E01 gene 1428969_at chr18 A2 75964 15.5 1 483 Arcn1 archain 1 1451089_a_at chr9 A5.2 213827 15.5 1 484 Plscr3 phospholipid scramblase 3 1449020_at chr11 B3|11 43.0 cM 70310 15.5 1 485 Sec22b SEC22 vesicle trafficking protein homolog B (S. cerevisiae) 1415766_at chr3 F2.2 20333 15.5 1 486 Dedd death effector domain-containing 1434995_s_at chr1 H2|1 90.0 cM 21945 15.5 1 487 Flot2 flotillin 2 1438164_x_at chr11 B5|11 46.0 cM 14252 15.5 1 488 Gas5 growth arrest specific 5 1419291_x_at chr1 H2.1 14455 15.5 1 489 Rnf167 ring finger protein 167 1430527_a_at chr11 B4 70510 15.5 1 490 Kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1417204_at chr5 G2 66913 15.5 1 491 Btd biotinidase 1417987_at chr14 B 26363 15.5 1 492 Stk11 serine/threonine kinase 11 1418644_a_at chr10 C1 20869 15.5 1 493 Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 1434000_at chr6 G2|6 71.2 cM 16653 15.5 1 494 Csnk1d casein kinase 1, delta 1437690_x_at chr11 E2 104318 15.5 1 495 Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 1415872_at chr11 B1.2 59013 15.5 1 496 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1420088_at chr12 C1-C3 18035 15.5 1 497 Pnrc1 proline-rich nuclear receptor coactivator 1 1433668_at chr4 A5 108767 15.5 1 498 Rab6 RAB6, member RAS oncogene family 1448305_at chr7 C4 19346 15.5 1 499 Ctr9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1422679_s_at chr7 F1|7 54.0 cM 22083 15.5 1 500 Usp7 ubiquitin specific peptidase 7 1434371_x_at chr16 A1 252870 15.5 1 501 Sharpin SHANK-associated RH domain interacting protein 1451267_at chr15 D3 106025 15.5 1 502 Pfn2 profilin 2 1418210_at chr3 D|3 29.3 cM 18645 15.5 1 503 Golga5 golgi autoantigen, golgin subfamily a, 5 1418447_at chr12 F1 27277 15.5 1 504 9030425E11Rik RIKEN cDNA 9030425E11 gene 1448250_at chr9 A5.1 71566 15.5 1 505 Rnf217 ring finger protein 217 1440179_x_at chr10 A4 268291 15.5 1 506 Rag1ap1 recombination activating gene 1 activating protein 1 1448948_at chr3 F1|3 44.3 cM 19729 15.5 1 507 Fam174a family with sequence similarity 174, member A 1419170_at chr1 D 67698 15.5 1 508 Amotl1 angiomotin-like 1 1428785_at chr9 A3 75723 15.5 1 509 Yipf4 Yip1 domain family, member 4 1426416_a_at chr17 E3 67864 15.5 1 510 Nars asparaginyl-tRNA synthetase 1428666_at chr18 E1 70223 15.5 1 511 Mrpl9 mitochondrial ribosomal protein L9 1437749_s_at chr3 F2 78523 15.5 1 512 Acadl acyl-Coenzyme A dehydrogenase, long-chain 1448987_at chr1 C3|1 27.3 cM 11363 15.5 1 513 Ccdc97 coiled-coil domain containing 97 1426692_at chr7 A3|7 5.5 cM 52132 15.5 1 514 Eif2b4 eukaryotic translation initiation factor 2B, subunit 4 delta 1449940_a_at chr5 B1 13667 15.5 1 515 Atad1 ATPase family, AAA domain containing 1 1448763_at chr19 C3 67979 15.5 1 516 Rab1 RAB1, member RAS oncogene family 1416082_at chr11 A3.1|11 10.9 cM 19324 15.5 1 517 Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 1426382_at chr17 E4-E5|17 50.8 cM 19043 15.5 1 518 Chic2 cysteine-rich hydrophobic domain 2 1429050_at chr5 D 74277 15.5 1 519 Slc44a1 solute carrier family 44, member 1 1433645_at chr4 B2 100434 15.5 1 520 Tmed9 transmembrane emp24 protein transport domain containing 9 1448268_at chr13 B2 67511 15.5 1 521 Rbbp7 retinoblastoma binding protein 7 1456227_x_at chrX F4 245688 15.5 1 522 Tmem19 transmembrane protein 19 1416261_at chr10 D2 67226 15.5 1 523 Rnf180 ring finger protein 180 1438306_at chr13 D1 71816 15.5 1 524 Fam172a family with sequence similarity 172, member A 1454723_at chr13 C1 68675 15.5 1 525 Srp72 signal recognition particle 72 1428876_at chr5 C3.3 66661 15.5 1 526 Slc44a2 solute carrier family 44, member 2 1438559_x_at chr9 A3 68682 15.5 1 527 Cyb5 cytochrome b-5 1416727_a_at chr18 E4|18 55.0 cM 109672 15.5 1 528 Pigq phosphatidylinositol glycan anchor biosynthesis, class Q 1438652_x_at chr17 B 14755 15.5 1 529 1110003E01Rik RIKEN cDNA 1110003E01 gene 1416768_at chr5 C3.1 68552 15.5 1 530 Stard7 START domain containing 7 1449628_s_at chr2 F1|2 62.5 cM 99138 15.5 1 531 Sec62 SEC62 homolog (S. cerevisiae) 1454697_at chr3 A3 69276 15.5 1 532 Atp13a1 ATPase type 13A1 1417475_at chr8 B3.3 170759 15.5 1 533

PAGE 6

Mib2 mindbomb homolog 2 (Drosophila) 1424862_s_at chr4 E2 76580 15.5 1 534 Fig4 FIG4 homolog (S. cerevisiae) 1419577_at chr10 B1 103199 15.5 1 535 Gtdc1 glycosyltransferase-like domain containing 1 1434290_at chr2 B 227835 15.5 1 536 Pfkm phosphofructokinase, muscle 1416780_at chr15 F1 18642 15.5 1 537 LOC100044423 /// Smek2 hypothetical protein LOC100044423 /// SMEK homolog 2, suppressor of mek1 (Dictyostelium) 1423197_a_at chr11 A3.3 100044423 /// 104570 15.5 1 538 F11r F11 receptor 1424595_at chr1 H2|1 93.3 cM 16456 15.5 1 539 Cntd1 Cyclin N-terminal domain containing 1 1439405_x_at chr11 D 68107 15.5 1 540 LOC636537 /// Ssr1 similar to signal sequence receptor, alpha /// signal sequence receptor, alpha 1417763_at chr13 A3.3 107513 /// 636537 15.5 1 541 Xpc xeroderma pigmentosum, complementation group C 1422532_at chr6 D 22591 15.5 1 542 Rtn3 reticulon 3 1418101_a_at chr19 A 20168 15.5 1 543 Styx serine/threonine/tyrosine interaction protein 1429711_at chr14 C1 56291 15.5 1 544 Tmem50a transmembrane protein 50A 1453155_at chr4 D3|4 65.71 cM 71817 15.5 1 545 Capza2 capping protein (actin filament) muscle Z-line, alpha 2 1423057_at chr6 A2|6 3.05 cM 12343 15.5 1 546 Arl8b ADP-ribosylation factor-like 8B 1428138_s_at chr6 E2 67166 15.5 1 547 4933403F05Rik RIKEN cDNA 4933403F05 gene 1434979_at chr18 E2 108654 15.5 1 548 Tcf19 transcription factor 19 1423809_at chr17 B1 106795 15.5 1 549 Rab7 RAB7, member RAS oncogene family 1415734_at chr6 D1|6 38.5 cM 19349 15.5 1 550 Ankrd28 ankyrin repeat domain 28 1434630_at chr14 B 105522 15.5 1 551 Dazap2 DAZ associated protein 2 1415796_at chr15 F1|15 60.0 cM 23994 15.5 1 552 Dnajc3 DnaJ (Hsp40) homolog, subfamily C, member 3 1449372_at chr14 E4 100037258 15.5 1 553 Ranbp2 RAN binding protein 2 1422621_at chr10 B4|10 30.0 cM 19386 15.5 1 554 Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1448863_a_at chr11 B5|11 45.1 cM 21927 15.5 1 555 Ccdc136 coiled-coil domain containing 136 1424699_at chr6 A3.3 232664 15.5 1 556 Cep68 centrosomal protein 68 1436034_at chr11 A3.1|11 10.91 cM 216543 15.5 1 557 Etl4 enhancer trap locus 4 1426880_at chr2 A3 208618 15.5 1 558 Nsun2 NOL1/NOP2/Sun domain family member 2 1423850_at chr13 C1|13 40.0 cM 28114 15.5 1 559 Rffl ring finger and FYVE like domain containing protein 1434432_at chr11 B5 67338 15.5 1 560 Uhrf2 ubiquitin-like, containing PHD and RING finger domains 2 1454920_at chr19 C1 109113 15.5 1 561 D10Ertd641e DNA segment, Chr 10, ERATO Doi 641, expressed 1419994_s_at chr10 B4|10 30.0 cM 52717 15.5 1 562 Ppp4r2 protein phosphatase 4, regulatory subunit 2 1433850_at chr6 D3 232314 15.5 1 563 Nedd4 neural precursor cell expressed, developmentally down-regulated 4 1450431_a_at chr9 D|9 40.0 cM 17999 15.5 1 564 Uso1 USO1 homolog, vesicle docking protein (yeast) 1424274_at chr5 E3 56041 15.5 1 565 Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 1450634_at chr16 B4 11964 15.5 1 566 Pdcd7 programmed cell death 7 1416377_at chr9 D 50996 15.5 1 567 Dnajb6 DnaJ (Hsp40) homolog, subfamily B, member 6 1448234_at chr5 B1 23950 15.5 1 568 Pldn pallidin 1417349_at chr2 E5|2 67.6 cM 18457 15.5 1 569 Kcnb1 /// Pacsin2 potassium voltage gated channel, Shab-related subfamily, member 1 1417810_a_at chr15 E1 /// chr2 H3|2 97.0 cM 16500 /// 23970 15.5 1 570 Gpsm2 G-protein signalling modulator 2 (AGS3-like, C. elegans) 1424895_at chr3 F3 76123 15.5 1 571 Smc1a structural maintenance of chromosomes 1A 1417830_at chrX F3 24061 15.5 1 572 Exoc3 exocyst complex component 3 1434750_at chr13 C1 211446 15.5 1 573 Rab11a RAB11a, member RAS oncogene family 1449256_a_at chr9 C 53869 15.5 1 574 Cd2ap CD2-associated protein 1420907_at chr17 B3 12488 15.5 1 575 Pctk1 PCTAIRE-motif protein kinase 1 1438625_s_at chrX A1.3|X 5.7 cM 18555 15.5 1 576 Csda cold shock domain protein A 1451012_a_at chr6 F3 56449 15.5 1 577 Fkbp7 FK506 binding protein 7 1416803_at chr2 C3|2 60.5 cM 14231 15.5 1 578 Exoc3 exocyst complex component 3 1455594_at chr13 C1 211446 15.5 1 579 Pdcd6ip programmed cell death 6 interacting protein 1448155_at chr9 F2 18571 15.5 1 580 Rab9 RAB9, member RAS oncogene family 1448391_at chrX F5 56382 15.5 1 581 Tmem77 transmembrane protein 77 1453731_a_at chr3 F3 67171 15.5 1 582 Fam188a family with sequence similarity 188, member A 1418963_at chr2 A1 66960 15.5 1 583 Stradb STE20-related kinase adaptor beta 1433544_at chr1 C1.3|1 34.0 cM 227154 15.5 1 584 Fam82a2 family with sequence similarity 82, member A2 1428196_a_at chr2 E5 67809 15.5 1 585 Zfp655 zinc finger protein 655 1428341_at chr5 G2 72611 15.5 1 586 Anxa3 annexin A3 1460330_at chr5 E3|5 54.0 cM 11745 15.5 1 587 Lrp10 low-density lipoprotein receptor-related protein 10 1416836_at chr14 C2-C3 65107 15.5 1 588 Lztfl1 leucine zipper transcription factor-like 1 1417170_at chr9 F|9 71.1 cM 93730 15.5 1 589 Bsdc1 BSD domain containing 1 1427270_a_at chr4 D2.2 100383 15.5 1 590 Xpot exportin, tRNA (nuclear export receptor for tRNAs) 1428772_at chr10 D3 73192 15.5 1 591 Zfp36l1 zinc finger protein 36, C3H type-like 1 1450644_at chr12 C3 12192 15.5 1 592 Mfap1a microfibrillar-associated protein 1A 1449445_x_at chr2 F1 67532 15.5 1 593 Stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1416861_at chr2 A2-B 20844 15.5 1 594 Notch3 Notch gene homolog 3 (Drosophila) 1421965_s_at chr17 B1|17 20.0 cM 18131 15.5 1 595 Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 1417369_at chr18 D1 15488 15.5 1 596 5730427N09Rik RIKEN cDNA 5730427N09 gene 1423131_at chr13 D1 59050 15.5 1 597 Wdr3 WD repeat domain 3 1433746_at chr3 F2.2 269470 15.5 1 598 Fbxw11 F-box and WD-40 domain protein 11 1437468_x_at chr11 A4 103583 15.5 1 599 Csnk1d casein kinase 1, delta 1415825_s_at chr11 E2 104318 15.5 1 600 Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1449731_s_at chr12 C1-C3 18035 15.5 1 601 Tcf25 transcription factor 25 (basic helix-loop-helix) 1451081_a_at chr8 E1|8 67.0 cM 66855 15.5 1 602 Tet2 tet oncogene family member 2 1455300_at chr3 G3 214133 15.5 1 603 Sptlc1 serine palmitoyltransferase, long chain base subunit 1 1422690_at chr13 B1 268656 15.5 1 604 Fam117b family with sequence similarity 117, member B 1434010_at chr1 C2 72750 15.5 1 605 Cops2 COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) 1423459_at chr2 F1|2 70.0 cM 12848 15.5 1 606 Ubr5 ubiquitin protein ligase E3 component n-recognin 5 1452718_at chr15 B3.1 70790 15.5 1 607 Atf1 activating transcription factor 1 1417296_at --11908 15.5 1 608 Dstyk dual serine/threonine and tyrosine protein kinase 1436301_at chr1 E4 213452 15.5 1 609 Arf3 ADP-ribosylation factor 3 1423973_a_at chr15 F2 11842 15.5 1 610 Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 1425550_a_at chr11 E1|11 65.0 cM 19084 15.5 1 611 Vopp1 vesicular, overexpressed in cancer, prosurvival protein 1 1423812_s_at chr6 B3 232023 15.5 1 612 2310044G17Rik RIKEN cDNA 2310044G17 gene 1424915_s_at chr12 D2 217732 15.5 1 613 Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 1434706_at chr1 A2 70675 15.5 1 614 Gas5 growth arrest specific 5 1449410_a_at chr1 H2.1 14455 15.5 1 615 Map3k1 mitogen-activated protein kinase kinase kinase 1 1424850_at chr13 D2.2|13 60.0 cM 26401 15.5 1 616 Cpsf2 cleavage and polyadenylation specific factor 2 1431089_at chr12 F1 51786 15.5 1 617 Abhd4 abhydrolase domain containing 4 1439259_x_at chr14 C2 105501 15.5 1 618 Nipbl Nipped-B homolog (Drosophila) 1453576_at chr15 A2 71175 15.5 1 619 Eif3c eukaryotic translation initiation factor 3, subunit C 1415858_at --56347 15.5 1 620 Atp7a ATPase, Cu++ transporting, alpha polypeptide 1418774_a_at chrX D|X 44.0 cM 11977 15.5 1 621 Ckap4 cytoskeleton-associated protein 4 1426754_x_at chr10 C1 216197 15.5 1 622 LOC100047588 /// Mark3 similar to MAP/microtubule affinity-regulating kinase 3 1418316_a_at chr12 F1 100047588 /// 17169 15.5 1 623 Snap23 synaptosomal-associated protein 23 1420896_at chr2 E5|2 61.8 cM 20619 15.5 1 624 Rell1 RELT-like 1 1427243_at chr5 C3.1 100532 15.5 1 625 Cttn cortactin 1433908_a_at chr7 F5 13043 15.5 1 626 Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 1451782_a_at chr17 C 63959 15.5 1 627 Ints12 integrator complex subunit 12 1428985_at chr3 H2 71793 15.5 1 628 Xpot exportin, tRNA (nuclear export receptor for tRNAs) 1428949_at chr10 D3 73192 15.5 1 629 Dym dymeclin 1437141_x_at chr18 E2 69190 15.5 1 630 Copg coatomer protein complex, subunit gamma 1416017_at chr6 D1|6 38.0 cM 54161 15.5 1 631 BC024659 cDNA sequence BC024659 1433986_at chr13A4|13 108934 15.5 1 632 Mtmr3 myotubularin related protein 3 1434042_s_at chr11 A1 74302 15.5 1 633 Smad1 MAD homolog 1 (Drosophila) 1459843_s_at chr8 C2 17125 15.5 1 634 5930434B04Rik RIKEN cDNA 5930434B04 gene 1435018_at chr2 A3 381356 15.5 1 635 Rgp1 RGP1 retrograde golgi transport homolog (S. cerevisiae) 1434338_at chr4 B1 242406 15.5 1 636 Mpp1 membrane protein, palmitoylated 1450919_at chrX A7.3|X 30.48 cM 17524 15.5 1 637 Mdm4 transformed mouse 3T3 cell double minute 4 1460542_s_at chr1 G-G|1 70.0 cM 17248 15.5 1 638 Lxn latexin 1416503_at chr3 E1|3 31.6 cM 17035 15.5 1 639 Ckap4 cytoskeleton-associated protein 4 1452181_at chr10 C1 216197 15.5 1 640

PAGE 7

Rnf10 ring finger protein 10 1423102_a_at chr5 F|5 62.0 cM 50849 15.5 1 641 Ttc33 tetratricopeptide repeat domain 33 1423958_a_at chr15 A1 67515 15.5 1 642 Inpp5f inositol polyphosphate-5-phosphatase F 1433542_at chr7 F3 101490 15.5 1 643 Ddx42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 1427022_at chr11 E1 72047 15.5 1 644 Unkl unkempt-like (Drosophila) 1428565_at chr17 A3.3 74154 15.5 1 645 Pxn paxillin 1456135_s_at chr5 F|5 60.0 cM 19303 15.5 1 646 Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1417866_at chr11 B5|11 45.1 cM 21927 15.5 1 647 Hmgn3 high mobility group nucleosomal binding domain 3 1434875_a_at chr9 E3.1 94353 15.5 1 648 Tmem66 transmembrane protein 66 1424039_at chr8 A4 67887 15.5 1 649 Pofut1 protein O-fucosyltransferase 1 1443881_at chr2 H2 140484 15.5 1 650 Chmp4b /// LOC674706 chromatin modifying protein 4B /// similar to zinc finger protein 341 1426240_at chr2 H2 674706 /// 75608 15.5 1 651 AI661453 expressed sequence AI661453 1425163_at chr17 C 224833 15.5 1 652 Ptpn9 protein tyrosine phosphatase, non-receptor type 9 1451037_at --56294 15.5 1 653 Ypel5 yippee-like 5 (Drosophila) 1433593_at chr17 E2 383295 15.5 1 654 Mnt max binding protein 1418192_at chr11 B-C|11 44.0 cM 17428 15.5 1 655 Csnk1a1 casein kinase 1, alpha 1 1428537_at chr18 D3 93687 15.5 1 656 Erlin2 ER lipid raft associated 2 1435223_at chr8 A2 244373 15.5 1 657 Msi2 Musashi homolog 2 (Drosophila) 1435521_at chr11 C 76626 15.5 1 658 Psat1 phosphoserine aminotransferase 1 1451064_a_at chr19 A|19 32.5 cM 107272 15.5 1 659 Mxi1 Max interacting protein 1 1450376_at chr19 D|19 49.5 cM 17859 15.5 1 660 D19Bwg1357e DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed 1426932_at chr19 C1|19 22.5 cM 52874 15.5 1 661 Rnf128 ring finger protein 128 1449036_at chrX F1 66889 15.5 1 662 Sp1 trans-acting transcription factor 1 1454852_at chr15 F3 20683 15.5 1 663 Ccndbp1 cyclin D-type binding-protein 1 1420745_a_at chr2 E5|2 68.6 cM 17151 15.5 1 664 Eif4a2 eukaryotic translation initiation factor 4A2 1450934_at chr16 B1|16 14.2 cM 13682 15.5 1 665 Kctd3 potassium channel tetramerisation domain containing 3 1455816_a_at chr1 H6 226823 15.5 1 666 Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1437539_at chr15 A1 105787 15.5 1 667 Prps2 phosphoribosyl pyrophosphate synthetase 2 1454843_at chrX 72.0 cM 110639 15.5 1 668 Irak1 interleukin-1 receptor-associated kinase 1 1460649_at chrX A7.3|X 29.6 cM 16179 15.5 1 669 Yipf2 Yip1 domain family, member 2 1438415_s_at chr9 A3 74766 15.5 1 670 Hp1bp3 heterochromatin protein 1, binding protein 3 1415751_at chr4 D3 15441 15.5 1 671 Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 1436179_a_at chr2 H4|2 106.0 cM 13002 15.5 1 672 Snx16 sorting nexin 16 1456041_at chr3 A1 74718 15.5 1 673 Zzz3 zinc finger, ZZ domain containing 3 1434332_at chr3 H3 108946 15.5 1 674 Polh polymerase (DNA directed), eta (RAD 30 related) 1447837_x_at chr17 C 80905 15.5 1 675 AU040320 expressed sequence AU040320 1452150_at chr4 D2.2 100317 15.5 1 676 Calu calumenin 1415870_at chr6 A3.3 12321 15.5 1 677 Tmem64 transmembrane protein 64 1434307_at chr4 A2 100201 15.5 1 678 Ewsr1 Ewing sarcoma breakpoint region 1 1417238_at chr11 A1-A3 14030 15.5 1 679 Fnbp1l formin binding protein 1-like 1434339_at chr3 G1 214459 15.5 1 680 Vkorc1 vitamin K epoxide reductase complex, subunit 1 1452770_at chr7 F3|7 61.0 cM 27973 15.5 1 681 Slc39a8 solute carrier family 39 (metal ion transporter), member 8 1416832_at chr3 G3|3 66.0 cM 67547 15.5 1 682 Chmp1b chromatin modifying protein 1B 1418817_at chr18 E1 67064 15.5 1 683 Rfc1 replication factor C (activator 1) 1 1418342_at chr5 C|5 39.0 cM 19687 15.5 1 684 Slc35a3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 1429648_at chr3 G1 229782 15.5 1 685 Gypc glycophorin C 1423878_at chr18 B1|18 17.0 cM 71683 15.5 1 686 Sdcbp syndecan binding protein 1423332_at chr4 A1 53378 15.5 1 687 Fbxo3 F-box protein 3 1423490_at chr2 E2 57443 15.5 1 688 Hccs holocytochrome c synthetase 1420890_at chrX F5 15159 15.5 1 689 Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 1426759_at chr17 E3 225028 15.5 1 690 Pdia3 protein disulfide isomerase associated 3 1423423_at chr2 E5|2 69.0 cM 14827 15.5 1 691 Grn granulin 1448148_at chr11 D|11 60.0 cM 14824 15.5 1 692 Setd3 SET domain containing 3 1451748_a_at chr12 F1|12 53.0 cM 52690 15.5 1 693 Cyfip1 cytoplasmic FMR1 interacting protein 1 1416329_at chr7 B5 20430 15.5 1 694 Rab12 RAB12, member RAS oncogene family 1427992_a_at chr17 E1.1 19328 15.5 1 695 Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1423126_at chr9 E3.3|9 51.0 cM 11933 15.5 1 696 Eif4b eukaryotic translation initiation factor 4B 1426380_at chr15 F3 75705 15.5 1 697 Zfp110 zinc finger protein 110 1437236_a_at chr7 A1|7 4.0 cM 65020 15.5 1 698 AI314180 expressed sequence AI314180 1452122_at chr4 B3 230249 15.5 1 699 Hnrnpm heterogeneous nuclear ribonucleoprotein M 1426698_a_at chr17 B1 76936 15.5 1 700 Ep400 E1A binding protein p400 1447349_s_at chr5 F 75560 15.5 1 701 Nudt18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 1435902_at chr14 D2 213484 15.5 1 702 AI747699 expressed sequence AI747699 1433914_at chr19 C1 381236 15.5 1 703 Canx calnexin 1428935_at chr11 B1.3|11 30.0 cM 12330 15.5 1 704 Mfsd9 major facilitator superfamily domain containing 9 1460619_at chr1 B 211798 15.5 1 705 Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 1448850_a_at chr2 H4|2 106.0 cM 13002 15.5 1 706 Cd82 CD82 antigen 1416401_at chr2 E1|2 49.6 cM 12521 15.5 1 707 Erbb2ip Erbb2 interacting protein 1428011_a_at chr13 D1 59079 15.5 1 708 Kctd10 potassium channel tetramerisation domain containing 10 1423694_at chr5 F 330171 15.5 1 709 Coro7 coronin 7 1437524_x_at chr16 A1|16 2.2 cM 78885 15.5 1 710 Sf3b2 splicing factor 3b, subunit 2 1438637_x_at chr19 A 319322 15.5 1 711 E130203B14Rik RIKEN cDNA E130203B14 gene 1455050_at chr14 B 320736 15.5 1 712 Map3k7ip2 mitogen-activated protein kinase kinase kinase 7 interacting protein 2 1423462_at chr10 A1 68652 15.5 1 713 E430025E21Rik RIKEN cDNA E430025E21 gene 1434132_at chr15 D1 223593 15.5 1 714 Ube2e2 ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) 1424358_at chr14 A2-A3 218793 15.5 1 715 Mbtps1 membrane-bound transcription factor peptidase, site 1 1448240_at chr8 E1 56453 15.5 1 716 Trim2 tripartite motif-containing 2 1417028_a_at chr3 F1 80890 15.5 1 717 Zfp46 zinc finger protein 46 1425231_a_at chr4 D3|4 65.9 cM 22704 15.5 1 718 Ppig peptidyl-prolyl isomerase G (cyclophilin G) 1436505_at chr2 C2 228005 15.5 1 719 Csda cold shock domain protein A 1435800_a_at chr6 F3 56449 15.5 1 720 Chd1 chromodomain helicase DNA binding protein 1 1457473_at chr17 A2|17 7.2 cM 12648 15.5 1 721 LOC100046560 /// Maged2 similar to melanoma antigen family D, 2 /// melanoma antigen, family D, 2 1426306_a_at chrX F2 100046560 /// 80884 15.5 1 722 Ubqln2 ubiquilin 2 1450021_at chrX F3 54609 15.5 1 723 Atg3 autophagy-related 3 (yeast) 1448993_at chr16 B5 67841 15.5 1 724 Rrp1 ribosomal RNA processing 1 homolog (S. cerevisiae) 1415957_a_at chr10 C1|10 42.0 cM 18114 15.5 1 725 Tmed10 transmembrane emp24-like trafficking protein 10 (yeast) 1424707_at chr12 D2 68581 15.5 1 726 Aga aspartylglucosaminidase 1434665_at chr8 B3 11593 15.5 1 727 Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 1422568_at chr11 B3 83431 15.5 1 728 Prkar2a protein kinase, cAMP dependent regulatory, type II alpha 1452915_at chr9 F2 19087 15.5 1 729 Kif5b kinesin family member 5B 1418430_at chr18 1.0 cM 16573 15.5 1 730 Etv3 ets variant gene 3 1418635_at chr3 F1 27049 15.5 1 731 Fam76b family with sequence similarity 76, member B 1426985_s_at chr9 A1 72826 15.5 1 732 D15Ertd621e DNA segment, Chr 15, ERATO Doi 621, expressed 1433724_at chr15 D1|15 33.2 cM 210998 15.5 1 733 Ror1 receptor tyrosine kinase-like orphan receptor 1 1429313_at chr4 49.6 cM 26563 15.5 1 734 Lrpap1 low density lipoprotein receptor-related protein associated protein 1 1436609_a_at chr5 B2|5 20.0 cM 16976 15.5 1 735 Mknk2 MAP kinase-interacting serine/threonine kinase 2 1418300_a_at chr10 C1 17347 15.5 1 736 Rbpj recombination signal binding protein for immunoglobulin kappa J region 1448957_at chr5 C1-C3|5 37.5 cM 19664 15.5 1 737 Lman1 lectin, mannose-binding, 1 1452671_s_at chr18 E1 70361 15.5 1 738 Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 1428645_at chr3 F2.3|3 48.8 cM 14679 15.5 1 739 Capn2 calpain 2 1416257_at chr1 H5 12334 15.5 1 740 Stx16 syntaxin 16 1429237_at chr2 H4 228960 15.5 1 741 Arf6 ADP-ribosylation factor 6 1418823_at chr12 C2 11845 15.5 1 742 Ddit4l DNA-damage-inducible transcript 4-like 1439332_at chr3 G3 73284 15.5 1 743 2310035C23Rik RIKEN cDNA 2310035C23 gene 1433726_at chr1 D|1 227446 15.5 1 744 Slc30a9 solute carrier family 30 (zinc transporter), member 9 1426668_at chr5 C3.1 109108 15.5 1 745 Dnajc14 DnaJ (Hsp40) homolog, subfamily C, member 14 1437546_at chr10 D3 74330 15.5 1 746 2610507B11Rik RIKEN cDNA 2610507B11 gene 1426820_at chr11 B5|11 44.93 cM 72503 15.5 1 747

PAGE 8

Rp2h retinitis pigmentosa 2 homolog (human) 1434061_at chrX A2 19889 15.5 1 748 Rrbp1 ribosome binding protein 1 1449221_a_at chr2 G1 81910 15.5 1 749 Inadl InaD-like (Drosophila) 1418983_at chr4 C6 12695 15.5 1 750 Dcaf7 DDB1 and CUL4 associated factor 7 1429151_at chr11 E1 71833 15.5 1 751 Rasa1 RAS p21 protein activator 1 1426476_at chr13 C3 218397 15.5 1 752 Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 1426994_at chr1 E2.1 98432 15.5 1 753 Prei4 preimplantation protein 4 1429144_at chr2 F3|2 74182 15.5 1 754 Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 1417018_at chr19 A 58859 15.5 1 755 Vps41 vacuolar protein sorting 41 (yeast) 1433666_s_at chr13 A2 218035 15.5 1 756 Chm choroidermia 1439824_at chrX E1 12662 15.5 1 757 2310076G13Rik RIKEN cDNA 2310076G13 gene 1453174_at --71938 15.5 1 758 Rnf170 ring finger protein 170 1434956_at --77733 15.5 1 759 Pftk1 PFTAIRE protein kinase 1 1419249_at chr5 A1|5 0.0 cM 18647 15.5 1 760 Rpl22 ribosomal protein L22 1448398_s_at chr4 E2 19934 15.5 1 761 Mapk1 mitogen-activated protein kinase 1 1426585_s_at chr16 A3|16 9.82 cM 26413 15.5 1 762 Tjp2 tight junction protein 2 1450985_a_at --21873 15.5 1 763 Rras Harvey rat sarcoma oncogene, subgroup R 1418448_at chr7 B4|7 23.0 cM 20130 15.5 1 764 Lrrfip2 leucine rich repeat (in FLII) interacting protein 2 1436510_a_at chr9 F2 71268 15.5 1 765 Tm9sf2 transmembrane 9 superfamily member 2 1455875_x_at chr14 E5|14 67.0 cM 68059 15.5 1 766 Atp8b1 ATPase, class I, type 8B, member 1 1455396_at chr18 E1 54670 15.5 1 767 Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 1427941_at chr12 E-F1|12 51.0 cM 192119 15.5 1 768 LOC100045106 /// Vstm2b hypothetical protein LOC100045106 /// V-set and transmembrane domain containing 2B 1419118_at chr7 B3 100045106 /// 58188 15.5 1 769 Mycbp2 MYC binding protein 2 1434937_at chr14 E2.3|14 54.58 cM 105689 15.5 1 770 Rab2a RAB2A, member RAS oncogene family 1419945_s_at chr4 A1 59021 15.5 1 771 Dnm1l dynamin 1-like 1428086_at chr16 A2 74006 15.5 1 772 Psen1 presenilin 1 1421853_at chr12 D1|12 37.0 cM 19164 15.5 1 773 Cttn cortactin 1423917_a_at chr7 F5 13043 15.5 1 774 Zfyve20 zinc finger, FYVE domain containing 20 1435093_at chr6 D3 78287 15.5 1 775 Serinc1 serine incorporator 1 1415838_at chr10 B4 56442 15.5 2 776 Os9 amplified in osteosarcoma 1426975_at chr10 D3 216440 15.5 2 777 Tmx4 thioredoxin-related transmembrane protein 4 1453120_at chr2 G1|2 77.0 cM 52837 15.5 2 778 Cd2ap CD2-associated protein 1420908_at chr17 B3 12488 15.5 2 779 Trim29 tripartite motif-containing 29 1424162_at chr9 A5.1 72169 15.5 2 780 2010109K11Rik RIKEN cDNA 2010109K11 gene 1436839_at chr12 A3 72123 15.5 2 781 Efr3a EFR3 homolog A (S. cerevisiae) 1416133_at chr15 D1 76740 15.5 2 782 Ano6 anoctamin 6 1455308_at chr15 F1 105722 15.5 2 783 Mbnl2 muscleblind-like 2 1455827_at chr14 E4 105559 15.5 2 784 Tubb6 tubulin, beta 6 1416431_at chr18 E1 67951 15.5 2 785 Osbpl1a oxysterol binding protein-like 1A 1460192_at chr18 A2 64291 15.5 2 786 Tjp1 tight junction protein 1 1417749_a_at chr7 C|7 28.5 cM 21872 15.5 2 787 Tmem9b TMEM9 domain family, member B 1417874_at chr7 E3 56786 15.5 2 788 D10Ertd610e DNA segment, Chr 10, ERATO Doi 610, expressed 1419978_s_at chr10 D3|10 70.0 cM 52666 15.5 2 789 Vps4b vacuolar protein sorting 4b (yeast) 1417007_a_at chr1 D 20479 15.5 2 790 Trim44 tripartite motif-containing 44 1421870_at chr2 E2 80985 15.5 2 791 Stag2 stromal antigen 2 1450396_at --20843 15.5 2 792 Dnajb14 DnaJ (Hsp40) homolog, subfamily B, member 14 1430561_at chr3 G3 70604 15.5 2 793 Tpp1 tripeptidyl peptidase I 1434768_at chr7 E3|7 50.0 cM 12751 15.5 2 794 Plcb4 phospholipase C, beta 4 1435771_at chr2 F3|2 77.0 cM 18798 15.5 2 795 Ddit4l DNA-damage-inducible transcript 4-like 1444139_at chr3 G3 73284 15.5 2 796 Tmem109 transmembrane protein 109 1456057_x_at chr19 A 68539 15.5 2 797 Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 1423662_at chrX A1.1 70495 15.5 2 798 Fndc3a fibronectin type III domain containing 3A 1426903_at chr14 D2 319448 15.5 2 799 Man2a1 mannosidase 2, alpha 1 1448647_at chr17 E1.2 17158 15.5 2 800 2700007P21Rik RIKEN cDNA 2700007P21 gene 1436859_at chr2 E3 212772 15.5 2 801 ----1458341_x_at ----15.5 2 802 Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 1437149_at chr6 D1|6 38.2 cM 21366 15.5 2 803 Trib2 tribbles homolog 2 (Drosophila) 1426640_s_at chr12 A1.1 217410 15.5 2 804 Arrdc3 arrestin domain containing 3 1454617_at chr13 C3 105171 15.5 2 805 Tlcd2 TLC domain containing 2 1432282_a_at chr11 B5 380712 15.5 2 806 Ehd2 EH-domain containing 2 1424157_at chr7 A2|7 15.13 cM 259300 15.5 2 807 Med13 mediator complex subunit 13 1453160_at chr11 C 327987 15.5 2 808 Sh3pxd2b SH3 and PX domains 2B 1435644_at chr11 A4 268396 15.5 2 809 C030007I09Rik RIKEN cDNA C030007I09 gene 1441980_at chr3 G3 109250 15.5 2 810 Plagl1 pleiomorphic adenoma gene-like 1 1426208_x_at chr10 A2|10 15.0 cM 22634 15.5 2 811 Samd8 sterile alpha motif domain containing 8 1434402_at chr14 B 67630 15.5 2 812 ----1435059_at ----15.5 2 813 Prrc1 proline-rich coiled-coil 1 1429652_at chr18 D3 73137 15.5 2 814 Ncoa1 nuclear receptor coactivator 1 1418594_a_at chr12 A2-A3 17977 15.5 2 815 Pja2 praja 2, RING-H2 motif containing 1434383_at chr17 E1.1 224938 15.5 2 816 Atrnl1 attractin like 1 1419922_s_at chr19 D2 226255 15.5 2 817 Gfpt1 glutamine fructose-6-phosphate transaminase 1 1428715_at chr6 D1|6 35.5 cM 14583 15.5 2 818 Tmed5 transmembrane emp24 protein transport domain containing 5 1424574_at chr5 E5 73130 15.5 2 819 Ipo7 importin 7 1454955_at chr7 F1 233726 15.5 2 820 ----1437073_x_at ----15.5 2 821 B2m beta-2 microglobulin 1449289_a_at chr2 F1-F3|2 69.0 cM 12010 15.5 2 822 Mertk c-mer proto-oncogene tyrosine kinase 1422869_at chr2 F1 17289 15.5 2 823 Mbd1 methyl-CpG binding domain protein 1 1437061_at chr18 E2|18 45.0 cM 17190 15.5 2 824 Mapre2 microtubule-associated protein, RP/EB family, member 2 1426245_s_at chr18 A2 212307 15.5 2 825 Plcg1 phospholipase C, gamma 1 1435149_at chr2 H2|2 92.0 cM 18803 15.5 2 826 Ampd2 adenosine monophosphate deaminase 2 (isoform L) 1438941_x_at chr3 F2.3|3 50.4 cM 109674 15.5 2 827 Serinc1 serine incorporator 1 1448108_at chr10 B4 56442 15.5 2 828 Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 1415963_at chrX E3 56258 15.5 2 829 Htatsf1 HIV TAT specific factor 1 1454760_at chrX A4 72459 15.5 2 830 Pex6 peroxisomal biogenesis factor 6 1424078_s_at chr17 C 224824 15.5 2 831 Itm2a integral membrane protein 2A 1451047_at chrX A2-A3 16431 15.5 2 832 Tmem170b Transmembrane protein 170B 1434556_at chr13 A4 621976 15.5 2 833 Timp2 tissue inhibitor of metalloproteinase 2 1454677_at chr11 E2|11 72.0 cM 21858 15.5 2 834 Kbtbd11 kelch repeat and BTB (POZ) domain containing 11 1435465_at chr8 A2 74901 15.5 2 835 Fam114a1 family with sequence similarity 114, member A1 1417272_at chr5 C3.3 68303 15.5 2 836 Tmem100 transmembrane protein 100 1449533_at chr11 C 67888 15.5 2 837 Cpne1 copine I 1433439_at chr2 H2 266692 15.5 2 838 Foxk1 forkhead box K1 1434655_at chr5 G2|5 82.0 cM 17425 15.5 2 839 Tmem164 transmembrane protein 164 1454741_s_at chrX F2 209497 15.5 2 840 Adam17 a disintegrin and metallopeptidase domain 17 1421858_at chr12 A1.3|12 3.0 cM 11491 15.5 2 841 B630019K06Rik RIKEN cDNA B630019K06 gene 1433452_at chrX A1.1 102941 15.5 2 842 5031439G07Rik RIKEN cDNA 5031439G07 gene 1435745_at chr15 E2 223739 15.5 2 843 Trim25 tripartite motif-containing 25 1425974_a_at chr11 C 217069 15.5 2 844 Rhoq ras homolog gene family, member Q 1427918_a_at chr17 E4|17 56.0 cM 104215 15.5 2 845 LOC100046855 similar to BKLF 1454666_at --100046855 15.5 2 846 Rgs3 regulator of G-protein signaling 3 1425296_a_at chr4 B3|4 35.0 cM 50780 15.5 2 847 Tmem65 transmembrane protein 65 1452942_at chr15 D1 74868 15.5 2 848 Heatr5a HEAT repeat containing 5A 1435241_at chr12 C1 320487 15.5 2 849 Lmbr1 limb region 1 1442371_at chr5 B1|5 15.8 cM 56873 15.5 2 850 Plekha1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1417965_at chr7 F3 101476 15.5 2 851 Fbxo11 F-box protein 11 1434108_at chr17 E4 225055 15.5 2 852 Tlcd1 TLC domain containing 1 1452132_at chr11 B5 68385 15.5 2 853 Ccdc47 coiled-coil domain containing 47 1424636_at chr11 E1 67163 15.5 2 854

PAGE 9

Rab22a RAB22A, member RAS oncogene family 1454988_s_at chr2 H4|2 100.5 cM 19334 15.5 2 855 Tlr2 toll-like receptor 2 1419132_at chr3 E3 24088 15.5 2 856 Osbpl11 oxysterol binding protein-like 11 1436027_at chr16 B3 106326 15.5 2 857 Mfap1a microfibrillar-associated protein 1A 1419370_a_at chr2 F1 67532 15.5 2 858 Antxr2 anthrax toxin receptor 2 1426708_at chr5 E3 71914 15.5 2 859 Gusb glucuronidase, beta 1448124_at chr5 G1.3 110006 15.5 2 860 Tcfap2a transcription factor AP-2, alpha 1421996_at chr13 A5-B1|13 25.0 cM 21418 15.5 2 861 Rab13 RAB13, member RAS oncogene family 1424894_at chr3 F1|3 45.0 cM 68328 15.5 2 862 Apcdd1 adenomatosis polyposis coli down-regulated 1 1418382_at chr18 E1 494504 15.5 2 863 Gnpda1 glucosamine-6-phosphate deaminase 1 1455065_x_at --26384 15.5 2 864 Sypl synaptophysin-like protein 1422881_s_at chr12 B2|12 15.0 cM 19027 15.5 2 865 Irf2bp2 interferon regulatory factor 2 binding protein 2 1433634_at chr8 E2 270110 15.5 2 866 Nbr1 neighbor of Brca1 gene 1 1448343_a_at chr11 D|11 60.5 cM 17966 15.5 2 867 2310014D11Rik RIKEN cDNA 2310014D11 gene 1428914_at --69633 15.5 2 868 Rrbp1 ribosome binding protein 1 1452767_at chr2 G1 81910 15.5 2 869 Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 1434210_s_at chr6 D2|6 39.0 cM 16206 15.5 2 870 Pkp3 plakophilin 3 1418831_at chr7 F5 56460 15.5 2 871 Bend5 BEN domain containing 5 1435351_at chr4 C7 67621 15.5 2 872 Lactb lactamase, beta 1449014_at chr9 D 80907 15.5 2 873 Ski ski sarcoma viral oncogene homolog (avian) 1426373_at chr4 E2|4 78.9 cM 20481 15.5 2 874 Tspyl5 testis-specific protein, Y-encoded-like 5 1455807_at chr15 B3.1 239364 15.5 2 875 4833428C12Rik RIKEN cDNA 4833428C12 gene 1435717_at --399589 15.5 2 876 Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 1415840_at chr9 E1 68801 15.5 2 877 Kdelc2 KDEL (Lys-Asp-Glu-Leu) containing 2 1453071_s_at chr9 A5.3 68304 15.5 2 878 Fcho2 FCH domain only 2 1437200_at chr13 D1 218503 15.5 2 879 Acad11 /// Nphp3 acyl-Coenzyme A dehydrogenase family, member 11 1454647_at chr9 F1 /// chr9 F1|9 61.0 cM 102632 /// 74025 15.5 2 880 Tcf4 transcription factor 4 1416723_at --21413 15.5 2 881 Znrf2 zinc and ring finger 2 1434017_at chr6 B3|6 26.0 cM 387524 15.5 2 882 Tpbg trophoblast glycoprotein 1423310_at chr9 E3.1 21983 15.5 2 883 Mboat2 membrane bound O-acyltransferase domain containing 2 1425029_a_at chr12 A1.3 67216 15.5 2 884 Lima1 LIM domain and actin binding 1 1435727_s_at chr15 F1|15 60.4 cM 65970 15.5 2 885 Pygl liver glycogen phosphorylase 1417741_at chr12 C2|12 30.0 cM 110095 15.5 2 886 Maoa monoamine oxidase A 1442676_at chrX A2|X 5.2 cM 17161 15.5 2 887 Heca headcase homolog (Drosophila) 1434477_at chr10 A2-A3 380629 15.5 2 888 Cep170 centrosomal protein 170 1437154_at chr1 H4 545389 15.5 2 889 Mkx mohawk homeobox 1437492_at chr18 A1|18 3.0 cM 210719 15.5 2 890 Hk1 hexokinase 1 1437974_a_at chr10 B4|10 30.0 cM 15275 15.5 2 891 Qk quaking 1417073_a_at chr17 A1|17 5.9 cM 19317 15.5 2 892 Mtss1 metastasis suppressor 1 1434036_at chr15 D1 211401 15.5 2 893 Emid2 EMI domain containing 2 1425310_a_at chr5 G1 140709 15.5 2 894 Atp9a ATPase, class II, type 9A 1427604_a_at --11981 15.5 2 895 Gns glucosamine (N-acetyl)-6-sulfatase 1433546_at chr10 D2 75612 15.5 2 896 Tmem9b TMEM9 domain family, member B 1448867_at chr7 E3 56786 15.5 2 897 Tpp1 tripeptidyl peptidase I 1448313_at chr7 E3|7 50.0 cM 12751 15.5 2 898 Slc35a5 solute carrier family 35, member A5 1419971_s_at chr16 B5|16 29.9 cM 74102 15.5 2 899 Lamp2 lysosomal-associated membrane protein 2 1428094_at chrX A3.3|X 13.0 cM 16784 15.5 2 900 Tjp2 tight junction protein 2 1434599_a_at --21873 15.5 2 901 Tox thymocyte selection-associated high mobility group box 1425484_at chr4 A1 252838 15.5 2 902 Sh3d19 SH3 domain protein D19 1449084_s_at chr3 F1 27059 15.5 2 903 Gmeb1 glucocorticoid modulatory element binding protein 1 1456232_at chr4 D3 56809 15.5 2 904 Syngr2 synaptogyrin 2 1417081_a_at chr11 E2 20973 15.5 2 905 Reep3 receptor accessory protein 3 1424780_a_at chr10 B5.1|10 30.0 cM 28193 15.5 2 906 Pcyox1 prenylcysteine oxidase 1 1423394_at chr6 D1 66881 15.5 2 907 Nrip1 nuclear receptor interacting protein 1 1449089_at chr16 C3.1 268903 15.5 2 908 9930012K11Rik RIKEN cDNA 9930012K11 gene 1433801_at chr14 D2 268759 15.5 2 909 Apcdd1 adenomatosis polyposis coli down-regulated 1 1454822_x_at chr18 E1 494504 15.5 2 910 Cdc42ep2 CDC42 effector protein (Rho GTPase binding) 2 1428750_at chr19 A|19 0.0 cM 104252 15.5 2 911 Foxq1 forkhead box Q1 1438558_x_at chr13 A3.2|13 17.0 cM 15220 15.5 2 912 Slc35f1 solute carrier family 35, member F1 1436719_at chr10 B3 215085 15.5 2 913 Ccdc88a coiled coil domain containing 88A 1436025_at chr11 A3.3 108686 15.5 2 914 Prnp prion protein 1448233_at chr2 F2|2 75.0 cM 19122 15.5 2 915 Lhfpl2 lipoma HMGIC fusion partner-like 2 1454847_at chr13 D1 218454 15.5 2 916 Tuft1 tuftelin 1 1416689_at chr3 F2 22156 15.5 2 917 Dnajc18 DnaJ (Hsp40) homolog, subfamily C, member 18 1434863_at chr18 B3 76594 15.5 2 918 Erp44 endoplasmic reticulum protein 44 1423246_at chr4 B1 76299 15.5 2 919 Dsel dermatan sulfate epimerase-like 1438407_at chr1 E2.2 319901 15.5 2 920 Copz2 coatomer protein complex, subunit zeta 2 1418455_at chr11 D 56358 15.5 2 921 Casp8 caspase 8 1424552_at chr1 B|1 30.1 cM 12370 15.5 2 922 Crtc1 CREB regulated transcription coactivator 1 1434476_at chr8 B3.3 382056 15.5 2 923 Rian RNA imprinted and accumulated in nucleus 1427580_a_at chr12 F1|12 54.5 cM 75745 15.5 2 924 Tpm2 tropomyosin 2, beta 1425028_a_at chr4 B1 22004 15.5 2 925 Chmp2b chromatin modifying protein 2B 1428252_at chr16 C1.3 68942 15.5 2 926 4933403F05Rik RIKEN cDNA 4933403F05 gene 1434977_at chr18 E2 108654 15.5 2 927 Tmprss13 transmembrane protease, serine 13 1427477_at chr9 A5.2 214531 15.5 2 928 Med13l mediator complex subunit 13-like 1434603_at chr5 F 76199 15.5 2 929 Cdyl chromodomain protein, Y chromosome-like 1418070_at chr13 A3.3|13 17.0 cM 12593 15.5 2 930 Igf1 insulin-like growth factor 1 1437401_at chr10 C1|10 48.0 cM 16000 15.5 2 931 2900097C17Rik RIKEN cDNA 2900097C17 gene 1428286_at chr2 H1 347740 15.5 2 932 Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 1435461_at chr3 F2.2|3 53.0 cM 99470 15.5 2 933 Syngr2 synaptogyrin 2 1448577_x_at chr11 E2 20973 15.5 2 934 Setd7 SET domain containing (lysine methyltransferase) 7 1435437_at chr3 C 73251 15.5 2 935 Itm2a integral membrane protein 2A 1423608_at chrX A2-A3 16431 15.5 2 936 Ubr3 ubiquitin protein ligase E3 component n-recognin 3 1429107_at chr2 C2 68795 15.5 2 937 Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 1434310_at chr1 C1.3 12168 15.5 2 938 Npnt nephronectin 1452107_s_at chr3 G3 114249 15.5 2 939 Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C 1450234_at chr19 A 73656 15.5 2 940 LOC100046186 /// Ramp3 similar to receptor activity modifying protein 3 /// receptor (calcitonin) activity modifying protein 3 1420401_a_at chr11 A1|11 2.1 cM 100046186 /// 56089 15.5 2 941 Mospd2 motile sperm domain containing 2 1424124_at chrX F5 76763 15.5 2 942 Baiap2l1 BAI1-associated protein 2-like 1 1424951_at chr5 G2 66898 15.5 2 943 LOC100048050 /// Lphn2 similar to calcium-independent alpha-latrotoxin receptor homolog 2 /// latrophilin 2 1434112_at chr3 H3 100048050 /// 99633 15.5 2 944 Palld palladin, cytoskeletal associated protein 1427228_at chr8 B3.3 72333 15.5 2 945 Ppp2r5c protein phosphatase 2, regulatory subunit B (B56), gamma isoform 1434205_at chr12 F1|12 57.0 cM 26931 15.5 2 946 Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 1434642_at chr5 E4 114664 15.5 2 947 Kitl kit ligand 1448117_at chr10 D1|10 57.0 cM 17311 15.5 2 948 Adam22 a disintegrin and metallopeptidase domain 22 1435293_at chr5 A1|5 0.0 cM 11496 15.5 2 949 Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1436297_a_at chr15 E1|15 66168 15.5 2 950 Smarca1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1460292_a_at chrX A3.2 93761 15.5 2 951 Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 1416625_at chr2 D 12258 15.5 2 952 Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1449485_at chr13 A3.3|13 13.9 cM 19766 15.5 2 953 Gphn gephyrin 1430038_at chr12 D2 268566 15.5 2 954 Wdr26 WD repeat domain 26 1451188_at chr1 H4 226757 15.5 2 955 Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 1421970_a_at chr3 E3|3 33.6 cM 14800 15.5 2 956 Slu7 SLU7 splicing factor homolog (S. cerevisiae) 1425488_at chr11 A5-B1.1 193116 15.5 2 957 Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 1437784_at chr4 A|4 4.4 cM 12395 15.5 2 958 Dsc2 desmocollin 2 1421156_a_at chr18 A2|18 7.0 cM 13506 15.5 2 959 C78339 expressed sequence C78339 1433476_at chr13 A5 97863 15.5 2 960 Irf2bp2 interferon regulatory factor 2 binding protein 2 1433633_at chr8 E2 270110 15.5 2 961

PAGE 10

Nr3c1 nuclear receptor subfamily 3, group C, member 1 1421867_at chr18 B3|18 20.0 cM 14815 15.5 2 962 Ston1 Stonin 1 1439496_at chr17 E5 77057 15.5 2 963 Ctsa cathepsin A 1448128_at chr2 H3|2 96.0 cM 19025 15.5 2 964 Dynlt3 dynein light chain Tctex-type 3 1449929_at chrX A1.1 67117 15.5 2 965 Leo1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1455293_at chr9 D 235497 15.5 2 966 Fbxo6 F-box protein 6 1417501_at chr4 E2|4 71.0 cM 50762 15.5 2 967 Col19a1 collagen, type XIX, alpha 1 1421698_a_at chr1 A3 12823 15.5 2 968 Ifi30 interferon gamma inducible protein 30 1422476_at chr8 B3.3 65972 15.5 2 969 Slc25a24 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 1452717_at chr3 F3 229731 15.5 2 970 Fkbp14 FK506 binding protein 14 1433481_at chr6 B3 231997 15.5 2 971 Bmp2k BMP2 inducible kinase 1437419_at chr5 E3 140780 15.5 2 972 Timp2 tissue inhibitor of metalloproteinase 2 1433662_s_at chr11 E2|11 72.0 cM 21858 15.5 2 973 Foxc1 forkhead box C1 1419486_at chr13 A3.2|13 20.0 cM 17300 15.5 2 974 Atxn1l ataxin 1-like 1455507_s_at chr8 D3|8 53.0 cM 52335 15.5 2 975 B230380D07Rik RIKEN cDNA B230380D07 gene 1436842_at chr9 D 235461 15.5 2 976 Fam171a1 family with sequence similarity 171, member A1 1438402_at chr2 A1 269233 15.5 2 977 Serinc5 serine incorporator 5 1433571_at chr13 C3 218442 15.5 2 978 Rasgrp3 RAS, guanyl releasing protein 3 1438030_at chr17 E2 240168 15.5 2 979 Lnpep leucyl/cystinyl aminopeptidase 1433747_at chr17 A3.2 240028 15.5 2 980 Mll5 myeloid/lymphoid or mixed-lineage leukemia 5 1434704_at chr5 A3 69188 15.5 2 981 Ctsz cathepsin Z 1417868_a_at chr2 H4|2 103.5 cM 64138 15.5 2 982 Spnb2 spectrin beta 2 1452143_at chr11 A3.3|11 13.0 cM 20742 15.5 2 983 Mxra8 matrix-remodelling associated 8 1452330_a_at chr4 E2|4 83.0 cM 74761 15.5 2 984 Prrx1 paired related homeobox 1 1439774_at chr1 H2.1|1 85.4 cM 18933 15.5 2 985 Foxj2 forkhead box J2 1420374_at chr6 F2 60611 15.5 2 986 Gphn gephyrin 1426463_at chr12 D2 268566 15.5 2 987 Lepre1 leprecan 1 1452752_at chr4 D1 56401 15.5 2 988 Reep3 Receptor accessory protein 3 1433976_at chr10 B5.1|10 30.0 cM 28193 15.5 2 989 Vim vimentin 1456292_a_at chr2 A2|2 7.0 cM 22352 15.5 2 990 Prkar1b protein kinase, cAMP dependent regulatory, type I beta 1440133_x_at chr5 G2|5 82.0 cM 19085 15.5 2 991 Pcyox1 prenylcysteine oxidase 1 1447277_s_at chr6 D1 66881 15.5 2 992 Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 1418203_at chr18 E1 58801 15.5 2 993 Zfp185 zinc finger protein 185 1420944_at chrX A7.3|X 28.95 cM 22673 15.5 2 994 Mtap2 microtubule-associated protein 2 1434194_at chr1 C3|1 33.7 cM 17756 15.5 2 995 Gopc golgi associated PDZ and coiled-coil motif containing 1421191_s_at chr10 B3 94221 15.5 2 996 Rcn3 reticulocalbin 3, EF-hand calcium binding domain 1424382_at chr7 B4|7 23.1 cM 52377 15.5 2 997 Fyn Fyn proto-oncogene 1448765_at chr10 B1|10 25.0 cM 14360 15.5 2 998 Pdgfrl platelet-derived growth factor receptor-like 1428896_at chr8 A4 68797 15.5 2 999 Nfib nuclear factor I/B 1448288_at chr4 C4-C6|4 38.6 cM 18028 15.5 2 1000 Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 1448104_at chr12 D1 104776 15.5 2 1001 C430014K11Rik RIKEN cDNA C430014K11 gene 1435550_at chr15 F1 320003 15.5 2 1002 Nfib nuclear factor I/B 1454834_at chr4 C4-C6|4 38.6 cM 18028 15.5 2 1003 Adcy1 adenylate cyclase 1 1456487_at chr11 A2 432530 15.5 2 1004 Tm9sf2 transmembrane 9 superfamily member 2 1460331_at chr14 E5|14 67.0 cM 68059 15.5 2 1005 Tcta T-cell leukemia translocation altered gene 1420124_s_at chr9 F2 102791 15.5 2 1006 Cpxm1 carboxypeptidase X 1 (M14 family) 1448901_at chr2 F1 56264 15.5 2 1007 Itfg1 integrin alpha FG-GAP repeat containing 1 1435637_at chr8 C4|8 39.0 cM 71927 15.5 2 1008 Prickle1 prickle like 1 (Drosophila) 1452249_at chr15 E3 106042 15.5 2 1009 Pgm2l1 phosphoglucomutase 2-like 1 1438774_s_at chr7 F1 70974 15.5 2 1010 Cul4a cullin 4A 1451971_at chr8 A1.1 99375 15.5 2 1011 Gpc4 glypican 4 1421088_at chrX A5|X 16.0 cM 14735 15.5 2 1012 Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform 1421957_a_at chr16 B3|16 22.85 cM 13026 15.5 2 1013 Add3 adducin 3 (gamma) 1423298_at chr19 D2|19 47.0 cM 27360 15.5 2 1014 Ltbp4 latent transforming growth factor beta binding protein 4 1436665_a_at chr7 A3 108075 15.5 2 1015 Nipal2 NIPA-like domain containing 2 1424612_at chr15 B3.1 223473 15.5 2 1016 Lipa lysosomal acid lipase A 1450872_s_at chr19 C1 16889 15.5 2 1017 Strn striatin, calmodulin binding protein 1455156_at chr17 E3 268980 15.5 2 1018 Cd34 CD34 antigen 1416072_at chr1 H6|1 106.6 cM 12490 15.5 2 1019 Tmem168 transmembrane protein 168 1451133_s_at chr6 A2 101118 15.5 2 1020 Fbxl7 F-box and leucine-rich repeat protein 7 1456220_at chr15 B1 448987 15.5 2 1021 Dip2c DIP2 disco-interacting protein 2 homolog C (Drosophila) 1429064_at chr13 A1 208440 15.5 2 1022 C230091D08Rik RIKEN cDNA C230091D08 gene 1438695_at chr7 B4 330544 15.5 2 1023 Ptpn13 protein tyrosine phosphatase, non-receptor type 13 1452127_a_at chr5 E-F|5 56.0 cM 19249 15.5 2 1024 Tbc1d8b TBC1 domain family, member 8B 1430133_at chrX F1 245638 15.5 2 1025 Spag9 sperm associated antigen 9 1433648_at chr11 C 70834 15.5 2 1026 Eif3a eukaryotic translation initiation factor 3, subunit A 1416660_at chr19 D 13669 15.5 2 1027 Slit3 Slit homolog 3 (Drosophila) 1427086_at --20564 15.5 2 1028 Wwtr1 WW domain containing transcription regulator 1 1417817_a_at chr3 D 97064 15.5 2 1029 Ski ski sarcoma viral oncogene homolog (avian) 1429192_at chr4 E2|4 78.9 cM 20481 15.5 2 1030 Sgms1 sphingomyelin synthase 1 1436499_at chr19 C1 208449 15.5 2 1031 Tacc1 transforming, acidic coiled-coil containing protein 1 1429590_at chr8 A2 320165 15.5 2 1032 Myst4 MYST histone acetyltransferase monocytic leukemia 4 1423508_at chr14 A3 54169 15.5 2 1033 Parva parvin, alpha 1431375_s_at chr7 F1 57342 15.5 2 1034 Jhdm1d jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae) 1435867_at chr6 B1 338523 15.5 2 1035 Csad cysteine sulfinic acid decarboxylase 1427981_a_at --246277 15.5 2 1036 Zbtb44 zinc finger and BTB domain containing 44 1435397_at chr9 A4 235132 15.5 2 1037 Zfp449 zinc finger protein 449 1439945_at chrX A4 78619 15.5 2 1038 Tbl1xr1 transducin (beta)-like 1X-linked receptor 1 1455109_at chr3 A3 81004 15.5 2 1039 Cat catalase 1416429_a_at chr2 E3|2 57.0 cM 12359 15.5 2 1040 Vldlr very low density lipoprotein receptor 1417900_a_at chr19 C1|19 20.0 cM 22359 15.5 2 1041 Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 1423792_a_at chr9 F3 67213 15.5 2 1042 2310022B05Rik RIKEN cDNA 2310022B05 gene 1428910_at chr8 E2 69551 15.5 2 1043 Atl3 atlastin GTPase 3 1435890_at chr19 A 109168 15.5 2 1044 Ndrg4 N-myc downstream regulated gene 4 1426615_s_at chr8 D1 234593 15.5 2 1045 Creb3l2 cAMP responsive element binding protein 3-like 2 1452381_at chr6 B1 208647 15.5 2 1046 Aldoc aldolase C, fructose-bisphosphate 1451461_a_at chr11 B5|11 44.98 cM 11676 15.5 2 1047 Lrrfip1 leucine rich repeat (in FLII) interacting protein 1 1433842_at chr1 D 16978 15.5 2 1048 Tbc1d12 TBC1D12: TBC1 domain family, member 12 1435675_at chr19 C3 209478 15.5 2 1049 Mef2a myocyte enhancer factor 2A 1452347_at chr7 C|7 33.0 cM 17258 15.5 2 1050 App amyloid beta (A4) precursor protein 1420621_a_at chr16 C3-qter|16 56.0 cM 11820 15.5 2 1051 Nbl1 neuroblastoma, suppression of tumorigenicity 1 1448428_at chr4 D3|4 70.0 cM 17965 15.5 2 1052 Rcor1 REST corepressor 1 1434336_s_at chr12 F1|12 57.0 cM 217864 15.5 2 1053 Dock11 dedicator of cytokinesis 11 1429028_at chrX A3.2 75974 15.5 2 1054 Tcf4 transcription factor 4 1434148_at --21413 15.5 2 1055 Fstl1 follistatin-like 1 1448259_at chr16 B3|16 27.3 cM 14314 15.5 2 1056 Ccdc47 coiled-coil domain containing 47 1424637_s_at chr11 E1 67163 15.5 2 1057 Rassf8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 1452283_at chr6 G3 71323 15.5 2 1058 ----1434861_at ----15.5 2 1059 5730471H19Rik RIKEN cDNA 5730471H19 gene 1455038_at chr2|2 632764 15.5 2 1060 ----1442936_at ----15.5 2 1061 Cds1 CDP-diacylglycerol synthase 1 1456114_at chr5 E4 74596 15.5 2 1062 Trip4 thyroid hormone receptor interactor 4 1422858_at chr9 D 56404 15.5 2 1063 Mecom MDS1 and EVI1 complex locus 1438325_at chr3 A3|3 14.4 cM 14013 15.5 2 1064 Mmp2 matrix metallopeptidase 2 1439364_a_at chr8 C5|8 44.0 cM 17390 15.5 2 1065 Snrk SNF related kinase 1448864_at chr9 F4 20623 15.5 2 1066 Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) 1428187_at chr16 B5 16423 15.5 2 1067 Lats2 large tumor suppressor 2 1439441_x_at chr14 C3 50523 15.5 2 1068

PAGE 11

Tmem109 transmembrane protein 109 1437008_x_at chr19 A 68539 15.5 2 1069 Cgnl1 cingulin-like 1 1452309_at chr9 D 68178 15.5 2 1070 Usp27x ubiquitin specific peptidase 27, X chromosome 1436004_at chrX A1.1|X 1.1 cM 54651 15.5 2 1071 Ndrg4 N-myc downstream regulated gene 4 1436188_a_at chr8 D1 234593 15.5 2 1072 Wwtr1 WW domain containing transcription regulator 1 1437155_a_at chr3 D 97064 15.5 2 1073 Zfyve26 zinc finger, FYVE domain containing 26 1452306_at chr12 C3 211978 15.5 2 1074 ----1455418_at ----15.5 2 1075 Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 1416168_at chr11 B5 20317 15.5 2 1076 Ldb2 LIM domain binding 2 1421101_a_at chr5 B3 16826 15.5 2 1077 Pmp22 peripheral myelin protein 22 1417133_at chr11 B3|11 34.45 cM 18858 15.5 2 1078 Sema3d sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 1429459_at chr5 A2 108151 15.5 2 1079 Ms4a6b membrane-spanning 4-domains, subfamily A, member 6B 1418826_at chr19 B 69774 15.5 2 1080 Tmem43 transmembrane protein 43 1426434_at chr6 D2 74122 15.5 2 1081 Ildr2 immunoglobulin-like domain containing receptor 2 1436293_x_at chr1 H2.3 100039795 15.5 2 1082 Agpat4 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) 1436640_x_at chr17 A2 68262 15.5 2 1083 Enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 1434580_at chr17 B3 224794 15.5 2 1084 Bcl2 B-cell leukemia/lymphoma 2 1437122_at chr1 E2.1|1 59.8 cM 12043 15.5 2 1085 Kctd12b potassium channel tetramerisation domain containing 12b 1440355_at chrX F3 207474 15.5 2 1086 Hspb1 heat shock protein 1 1425964_x_at chr5 G2|5 76.0 cM 15507 15.5 2 1087 Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 1454855_at chr5 A3 50791 15.5 2 1088 ----1434379_at ----15.5 2 1089 Zdhhc14 zinc finger, DHHC domain containing 14 1438619_x_at chr17 A1 224454 15.5 2 1090 ----1445758_at ----15.5 2 1091 Masp1 mannan-binding lectin serine peptidase 1 1438602_s_at chr16 B2-B3 17174 15.5 2 1092 Esam endothelial cell-specific adhesion molecule 1460356_at chr9 B 69524 15.5 2 1093 Stat6 signal transducer and activator of transcription 6 1426353_at chr10 D3|10 70.0 cM 20852 15.5 2 1094 2210408K08Rik RIKEN cDNA 2210408K08 gene 1437087_at --108743 15.5 2 1095 Cugbp2 CUG triplet repeat, RNA binding protein 2 1450069_a_at chr2 A2-A3 14007 15.5 2 1096 Nrp2 neuropilin 2 1435349_at chr1 C2 18187 15.5 2 1097 Antxr1 anthrax toxin receptor 1 1451446_at chr6 D1 69538 15.5 2 1098 Emilin1 elastin microfibril interfacer 1 1416414_at chr5 B1 100952 15.5 2 1099 Mmp15 matrix metallopeptidase 15 1422597_at chr8 D1|8 45.5 cM 17388 15.5 2 1100 Nab1 Ngfi-A binding protein 1 1417624_at chr1 C1.1|1 27.0 cM 17936 15.5 2 1101 Irgq immunity-related GTPase family, Q 1435540_at chr7 A3 210146 15.5 2 1102 BC038331 cDNA sequence BC038331 1458295_at --408056 15.5 2 1103 Myd88 myeloid differentiation primary response gene 88 1419272_at chr9 F3|9 70.0 cM 17874 15.5 2 1104 Trim25 tripartite motif-containing 25 1419879_s_at chr11 C 217069 15.5 2 1105 Lix1l Lix1-like 1436546_at chr3 F2.1 280411 15.5 2 1106 Atp8a1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 1423597_at chr5 C3.1 11980 15.5 2 1107 Capn7 calpain 7 1423097_s_at chr14 B 12339 15.5 2 1108 LOC676870 /// Pbx1 region containing RIKEN cDNA 2310056B04 gene; pre B-cell leukemia transcription factor 1 /// pre B-cell leukemia transcription factor 1 1428647_at chr1 H2.3|1 88.1 cM 18514 /// 676870 15.5 2 1109 Frmd4a FERM domain containing 4A 1434285_at chr2 A1 209630 15.5 2 1110 Foxn2 forkhead box N2 1454831_at chr17 E5 14236 15.5 2 1111 Pten phosphatase and tensin homolog 1454722_at chr19 C1|19 24.5 cM 19211 15.5 2 1112 Rab27b RAB27b, member RAS oncogene family 1417214_at chr18 E2|18 45.0 cM 80718 15.5 2 1113 Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 1417329_at chr2 G2 54338 15.5 2 1114 Capn7 calpain 7 1423098_at chr14 B 12339 15.5 2 1115 Ccdc3 coiled-coil domain containing 3 1428549_at chr2 A1 74186 15.5 2 1116 Emp2 epithelial membrane protein 2 1433670_at chr16 A1|16 2.4 cM 13731 15.5 2 1117 Plekha2 pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2 1417288_at chr8 A2 83436 15.5 2 1118 Acad11 /// Nphp3 acyl-Coenzyme A dehydrogenase family, member 11 /// nephronophthisis 3 (adolescent) 1433545_s_at chr9 F1 /// chr9 F1|9 61.0 cM 102632 /// 74025 15.5 2 1119 Dock9 dedicator of cytokinesis 9 1450932_s_at chr14 E5|14 67.0 cM 105445 15.5 2 1120 Cxxc4 CXXC finger 4 1437351_at chr3 G3 319478 15.5 2 1121 Kank2 KN motif and ankyrin repeat domains 2 1460559_at chr9 A3 235041 15.5 2 1122 Pcnx pecanex homolog (Drosophila) 1419047_at chr12 D1 54604 15.5 2 1123 Sipa1l1 signal-induced proliferation-associated 1 like 1 1439755_at chr12 D1 217692 15.5 2 1124 Pros1 protein S (alpha) 1426246_at chr16 C1.3 19128 15.5 2 1125 Cbx6 chromobox homolog 6 1429290_at chr15 E1 494448 15.5 2 1126 Acp5 acid phosphatase 5, tartrate resistant 1431609_a_at chr9 A3|9 6.0 cM 11433 15.5 2 1127 1190003J15Rik RIKEN cDNA 1190003J15 gene 1455186_a_at chr7 F5 76974 15.5 2 1128 Gm10397 predicted gene 10397 1435740_at --100038401 15.5 2 1129 Epha7 Eph receptor A7 1451991_at chr4 A4|4 1.9 cM 13841 15.5 2 1130 Evpl envoplakin 1419133_at chr11 E1 14027 15.5 2 1131 Emp2 epithelial membrane protein 2 1425272_at chr16 A1|16 2.4 cM 13731 15.5 2 1132 D830012I24Rik RIKEN cDNA D830012I24 gene 1435822_at --320070 15.5 2 1133 Bscl2 Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) 1437345_a_at chr19 A|19 4.0 cM 14705 15.5 2 1134 Ppap2a phosphatidic acid phosphatase type 2A 1422619_at chr13 D2.2 19012 15.5 2 1135 Lsamp limbic system-associated membrane protein 1435895_at chr16 B5 268890 15.5 2 1136 Gprc5b G protein-coupled receptor, family C, group 5, member B 1424613_at chr7 F3 64297 15.5 2 1137 Foxo3 forkhead box O3 1434832_at chr10 B2|10 30.0 cM 56484 15.5 2 1138 Sdf4 stromal cell derived factor 4 1455584_at chr4 E2 20318 15.5 2 1139 Ankrd13a ankyrin repeat domain 13a 1460428_at chr5 F 68420 15.5 2 1140 1110067D22Rik RIKEN cDNA 1110067D22 gene 1424318_at chr11 A3.1|11 11.0 cM 216551 15.5 2 1141 Lats2 large tumor suppressor 2 1437101_at chr14 C3 50523 15.5 2 1142 Epha3 Eph receptor A3 1455426_at chr16 C1.3 13837 15.5 2 1143 Tyrobp TYRO protein tyrosine kinase binding protein 1450792_at chr7 B|7 10.0 cM 22177 15.5 2 1144 Stat1 signal transducer and activator of transcription 1 1450034_at chr1 C1.1|1 25.9 cM 20846 15.5 2 1145 Capn7 calpain 7 1423096_at chr14 B 12339 15.5 2 1146 Limch1 LIM and calponin homology domains 1 1435106_at chr5 C3.1 77569 15.5 2 1147 Aebp2 AE binding protein 2 1437743_at chr6 G1 11569 15.5 2 1148 Mtap4 microtubule-associated protein 4 1416092_a_at chr9 F2|9 58.0 cM 17758 15.5 2 1149 Tacstd2 tumor-associated calcium signal transducer 2 1423323_at --56753 15.5 2 1150 Clip4 CAP-GLY domain containing linker protein family, member 4 1427278_at chr17 E2 78785 15.5 2 1151 Mef2a myocyte enhancer factor 2A 1427185_at chr7 C|7 33.0 cM 17258 15.5 2 1152 Kat2b K(lysine) acetyltransferase 2B 1434037_s_at chr17 C|17 30.0 cM 18519 15.5 2 1153 Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 1452056_s_at chr3 G3 19055 15.5 2 1154 Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) 1419554_at chr16 B5 16423 15.5 2 1155 Fam57a family with sequence similarity 57, member A 1435076_at chr11 B5 116972 15.5 2 1156 Stxbp6 syntaxin binding protein 6 (amisyn) 1425749_at chr12 B3 217517 15.5 2 1157 Map3k7ip3 mitogen-activated protein kinase kinase kinase 7 interacting protein 3 1428762_at chrX C1 66724 15.5 2 1158 Ncoa2 nuclear receptor coactivator 2 1435233_at chr1 A3-A5|1 1.0 cM 17978 15.5 2 1159 Cat catalase 1416430_at chr2 E3|2 57.0 cM 12359 15.5 2 1160 Dlc1 deleted in liver cancer 1 1436173_at chr8 A4-B2|8 21.0 cM 50768 15.5 2 1161 Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 1452284_at chr6 A3.1 19283 15.5 2 1162 Med13l mediator complex subunit 13-like 1434602_at chr5 F 76199 15.5 2 1163 Phf3 PHD finger protein 3 1429000_at chr1 A5 213109 15.5 2 1164 Vim vimentin 1450641_at chr2 A2|2 7.0 cM 22352 15.5 2 1165 BC049807 cDNA sequence BC049807 1437696_at chr17 A3.2 381066 15.5 2 1166 Rnf144b ring finger protein 144B 1439153_at chr13 A5 218215 15.5 2 1167 Lhfp lipoma HMGIC fusion partner 1433776_at chr3 C 108927 15.5 2 1168 Itpripl2 inositol 1,4,5-triphosphate receptor interacting protein-like 2 1435777_at chr7 F1 319622 15.5 2 1169 Inpp5b inositol polyphosphate-5-phosphatase B 1451330_a_at chr4 D2|4 56.0 cM 16330 15.5 2 1170 Kidins220 kinase D-interacting substrate 220 1433852_at chr12 A1.3 77480 15.5 2 1171 Lnx2 ligand of numb-protein X 2 1460249_at chr5 G2 140887 15.5 2 1172 Pcdh7 Protocadherin 7 1437442_at chr5 C3-D 54216 15.5 2 1173 Cxx1c CAAX box 1 homolog C (human) 1450080_at chrX A5 72865 15.5 2 1174 Slc25a46 solute carrier family 25, member 46 1418134_at chr18 B1 67453 15.5 2 1175

PAGE 12

Epha3 Eph receptor A3 1425575_at chr16 C1.3 13837 15.5 2 1176 Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 1452774_at chr2 A7.2 229279 15.5 2 1177 Epb4.1l3 erythrocyte protein band 4.1-like 3 1419062_at chr17 E1.3|17 42.5 cM 13823 15.5 2 1178 Rab11fip2 RAB11 family interacting protein 2 (class I) 1455169_at chr19 D3 74998 15.5 2 1179 Dsc2 desmocollin 2 1426911_at chr18 A2|18 7.0 cM 13506 15.5 2 1180 2510009E07Rik RIKEN cDNA 2510009E07 gene 1428097_at chr16 B1 72190 15.5 2 1181 Tmem106b transmembrane protein 106B 1435074_at chr6 A2 71900 15.5 2 1182 Wipi1 WD repeat domain, phosphoinositide interacting 1 1456624_at chr11 E1|11 68.0 cM 52639 15.5 2 1183 Bcl6b B-cell CLL/lymphoma 6, member B 1418421_at chr11 B4 12029 15.5 2 1184 Bscl2 Bernardinelli-Seip congenital lipodystrophy 2 homolog (human) 1420632_a_at chr19 A|19 4.0 cM 14705 15.5 2 1185 2310002J15Rik RIKEN cDNA 2310002J15 gene 1437145_s_at chr2 A3 67859 15.5 2 1186 Zfp36 zinc finger protein 36 1452519_a_at chr7 A3|7 10.2 cM 22695 15.5 2 1187 Mtus1 mitochondrial tumor suppressor 1 1454824_s_at chr8 A4 102103 15.5 2 1188 Neu3 neuraminidase 3 1419339_at --50877 15.5 2 1189 Tacc1 transforming, acidic coiled-coil containing protein 1 1454909_at chr8 A2 320165 15.5 2 1190 Cplx2 complexin 2 1421477_at chr13 B1 12890 15.5 2 1191 Prss23 protease, serine, 23 1437671_x_at chr7 E1 76453 15.5 2 1192 Wdr47 WD repeat domain 47 1434558_at chr3 F3 99512 15.5 2 1193 Ttc30b tetratricopeptide repeat domain 30B 1423672_at chr2 C3 72421 15.5 2 1194 Lamp2 lysosomal-associated membrane protein 2 1416343_a_at chrX A3.3|X 13.0 cM 16784 15.5 2 1195 Tnks2 Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 1447522_s_at chr19 C2 74493 15.5 2 1196 Nsbp1 nucleosome binding protein 1 1418152_at chrX D 50887 15.5 2 1197 Acpl2 acid phosphatase-like 2 1429390_at chr9 E3.3 235534 15.5 2 1198 Rbms3 RNA binding motif, single stranded interacting protein 1436938_at chr9 F3 207181 15.5 2 1199 LOC676870 /// Pbx1 region containing RIKEN cDNA 2310056B04 gene; pre B-cell leukemia transcription factor 1 1425383_a_at chr1 H2.3|1 88.1 cM 18514 /// 676870 15.5 2 1200 Gns glucosamine (N-acetyl)-6-sulfatase 1433488_x_at chr10 D2 75612 15.5 2 1201 Edem3 ER degradation enhancer, mannosidase alpha-like 3 1460401_at chr1 G2 66967 15.5 2 1202 Ids iduronate 2-sulfatase 1455481_at chrX A7.1|X 27.0 cM 15931 15.5 2 1203 Crybg3 beta-gamma crystallin domain containing 3 1434410_at chr16 C1.3 224273 15.5 2 1204 Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase 5 1425702_a_at chr17 C|17 23.5 cM 83965 15.5 2 1205 Man2a2 mannosidase 2, alpha 2 1435203_at chr7 D2 140481 15.5 2 1206 Arsb arylsulfatase B 1429189_at chr13 C3-D1|13 50.0 cM 11881 15.5 2 1207 C78339 expressed sequence C78339 1433475_a_at chr13 A5 97863 15.5 2 1208 D030029J20Rik RIKEN cDNA D030029J20 gene 1437885_at --99324 15.5 2 1209 Tmbim1 transmembrane BAX inhibitor motif containing 1 1417162_at chr1 C3 69660 15.5 2 1210 Dusp3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) 1434472_at chr11 D 72349 15.5 2 1211 Epha7 Eph receptor A7 1443485_at chr4 A4|4 1.9 cM 13841 15.5 2 1212 BC013529 cDNA sequence BC013529 1424025_at chr10 A1 215751 15.5 2 1213 Arsk arylsulfatase K 1453109_at chr13 C1 77041 15.5 2 1214 Dsp desmoplakin 1435494_s_at chr13 A3.3 109620 15.5 2 1215 Selenbp1 selenium binding protein 1 1417580_s_at chr3 F2.1|3 43.25 cM 20341 15.5 2 1216 Palld palladin, cytoskeletal associated protein 1433768_at chr8 B3.3 72333 15.5 2 1217 Itgav integrin alpha V 1452784_at chr2 D|2 46.0 cM 16410 15.5 2 1218 Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 1416408_at chr11 E2 11430 15.5 2 1219 Ctnnd1 catenin (cadherin associated protein), delta 1 1422450_at chr2 D|2 47.8 cM 12388 15.5 2 1220 Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) 1420563_at chrX A3.3-A4|X 13.3 cM 53623 15.5 2 1221 Tspyl4 TSPY-like 4 1424029_at chr10 B1|10 22.0 cM 72480 15.5 2 1222 Aff2 AF4/FMR2 family, member 2 1443847_x_at chrX A5 14266 15.5 2 1223 Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1452291_at chr5 C3.1 212285 15.5 2 1224 Klf3 /// LOC100046855 Kruppel-like factor 3 (basic) /// similar to BKLF 1421604_a_at chr5 C3.1 100046855 /// 16599 15.5 2 1225 Boc biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein 1426869_at chr16 B5 117606 15.5 2 1226 Wnk1 WNK lysine deficient protein kinase 1 1433676_at chr6 F1 232341 15.5 2 1227 Prkcdbp protein kinase C, delta binding protein 1423771_at chr7 F1 109042 15.5 2 1228 Ubr3 ubiquitin protein ligase E3 component n-recognin 3 1460455_at chr2 C2 68795 15.5 2 1229 Klf4 Kruppel-like factor 4 (gut) 1417395_at chr4 B3|4 19.7 cM 16600 15.5 2 1230 Dmxl2 Dmx-like 2 1428749_at chr9 C 235380 15.5 2 1231 Sash1 SAM and SH3 domain containing 1 1448005_at chr10 A1 70097 15.5 2 1232 Svip small VCP/p97-interacting protein 1429146_at chr7 B4 75744 15.5 2 1233 Lad1 ladinin 1418449_at chr1 E4 16763 15.5 2 1234 Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 1437688_x_at chrX A1.1 70495 15.5 2 1235 Scamp1 secretory carrier membrane protein 1 1426775_s_at chr13 D1 107767 15.5 2 1236 Macc1 metastasis associated in colon cancer 1 1457044_at chr12 F2 238455 15.5 2 1237 ----1443755_at ----15.5 2 1238 Ccdc47 coiled-coil domain containing 47 1451420_at chr11 E1 67163 15.5 2 1239 Trip12 thyroid hormone receptor interactor 12 1423901_at chr1 F 14897 15.5 2 1240 Mgat5 mannoside acetylglucosaminyltransferase 5 1428643_at chr1 E3 107895 15.5 2 1241 Zxdb zinc finger, X-linked, duplicated B 1455817_x_at chrX C3 668166 15.5 2 1242 Wdr26 WD repeat domain 26 1435478_at chr1 H4 226757 15.5 2 1243 Dpysl3 dihydropyrimidinase-like 3 1415877_at chr18 B3 22240 15.5 2 1244 Rrbp1 ribosome binding protein 1 1426123_a_at chr2 G1 81910 15.5 2 1245 Kcnk6 potassium inwardly-rectifying channel, subfamily K, member 6 1435342_at chr7 B1|7 9.5 cM 52150 15.5 2 1246 Fam70a family with sequence similarity 70, member A 1439006_x_at chrX A3.3 245386 15.5 2 1247 Pcdhb9 protocadherin beta 9 1422640_at chr18 B3 93880 15.5 2 1248 Pcdh17 protocadherin 17 1436920_at chr14 D3 219228 15.5 2 1249 Tshz1 teashirt zinc finger family member 1 1427232_at chr18 E4|18 56.0 cM 110796 15.5 2 1250 Pdzk1ip1 PDZK1 interacting protein 1 1455477_s_at chr4 D1 67182 15.5 2 1251 Dkk2 dickkopf homolog 2 (Xenopus laevis) 1420512_at chr3 H2 56811 15.5 2 1252 Etv1 ets variant gene 1 1422607_at chr12 A3-B1|12 18.5 cM 14009 15.5 2 1253 Grin3a glutamate receptor ionotropic, NMDA3A 1438866_at chr4 B1 242443 15.5 2 1254 Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 1453724_a_at chr11 B5 20317 15.5 2 1255 C1qb complement component 1, q subcomponent, beta polypeptide 1417063_at chr4 D3|4 66.1 cM 12260 15.5 2 1256 Ndrg2 N-myc downstream regulated gene 2 1448154_at chr14 C2 29811 15.5 2 1257 Cd53 CD53 antigen 1448617_at chr3 F2.3|3 50.5 cM 12508 15.5 2 1258 Ghr growth hormone receptor 1417962_s_at chr15 A1|15 4.6 cM 14600 15.5 2 1259 Eef2k eukaryotic elongation factor-2 kinase 1437829_s_at chr7 F3 13631 15.5 2 1260 Camk2d calcium/calmodulin-dependent protein kinase II, delta 1422659_at chr3 G1-G2 108058 15.5 2 1261 Slc39a2 solute carrier family 39 (zinc transporter), member 2 1443163_at chr14 C2 214922 15.5 2 1262 Mmp14 Matrix metallopeptidase 14 (membrane-inserted) 1440920_at chr14 C2|14 12.5 cM 17387 15.5 2 1263 Peg3 paternally expressed 3 1417356_at chr7 A2-B1|7 6.5 cM 18616 15.5 2 1264 Cast calpastatin 1435972_at chr13 C1 12380 15.5 2 1265 Ccpg1 cell cycle progression 1 1424420_at chr9 D 72278 15.5 2 1266 Rab3d RAB3D, member RAS oncogene family 1418890_a_at chr9 A2-A3 19340 15.5 2 1267 Pcdha1 /// Pcdha10 /// Pcdha11 /// Pcdha12 /// Pcdha2 /// Pcdha3 /// Pcdha4 / protocadherin alpha 1 1420798_s_at chr18 B2-B3 /// chr18 B3 116731 /// 12936 /// 12937 /// 12939 /// 12941 /// 12942 /// 12943 /// 192 15.5 2 1268 Tmem40 transmembrane protein 40 1424966_at chr6 E3 94346 15.5 2 1269 Slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 1435387_at chr15 E3 239606 15.5 2 1270 Ifi35 interferon-induced protein 35 1445897_s_at chr11 D 70110 15.5 2 1271 Zdhhc14 zinc finger, DHHC domain containing 14 1437614_x_at chr17 A1 224454 15.5 2 1272 Tbx18 T-box18 1449871_at chr9 E3.2|9 48.5 cM 76365 15.5 2 1273 Hey2 hairy/enhancer-of-split related with YRPW motif 2 1418106_at chr10 A4 15214 15.5 2 1274 Aff3 AF4/FMR2 family, member 3 1433939_at chr1 B|1 18.7 cM 16764 15.5 2 1275 Msrb3 methionine sulfoxide reductase B3 1439151_at chr10 D2 320183 15.5 2 1276 LOC100046344 /// LOC100047753 /// Nme1 similar to Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) 1435277_x_at chr11 D 100046344 /// 100047753 /// 18102 15.5 2 1277 Dlc1 deleted in liver cancer 1 1460602_at chr8 A4-B2|8 21.0 cM 50768 15.5 2 1278 Irf2bp2 interferon regulatory factor 2 binding protein 2 1433632_at chr8 E2 270110 15.5 2 1279 8430436O14Rik RIKEN cDNA 8430436O14 gene 1452762_at --71506 15.5 2 1280 B230312A22Rik RIKEN cDNA B230312A22 gene 1434059_at chr4 A5 230088 15.5 2 1281 Gsn gelsolin 1436991_x_at chr2 B|2 24.5 cM 227753 15.5 2 1282

PAGE 13

1810011O10Rik RIKEN cDNA 1810011O10 gene 1435595_at chr8 A2 69068 15.5 2 1283 Grhl1 /// LOC100043996 grainyhead-like 1 (Drosophila) /// similar to Grhl1 protein 1424030_at chr12 A1.3 100043996 /// 195733 15.5 2 1284 Cdh13 cadherin 13 1434115_at chr8 E1|8 64.0 cM 12554 15.5 2 1285 Mylk myosin, light polypeptide kinase 1425505_at chr16 B3 107589 15.5 2 1286 Col3a1 collagen, type III, alpha 1 1427884_at chr1 C1.1|1 25.0 cM 12825 15.5 2 1287 Prnd prion protein dublet 1425681_a_at chr2 F2|2 75.0 cM 26434 15.5 2 1288 Bace1 beta-site APP cleaving enzyme 1 1455826_a_at chr9 A5.2 23821 15.5 2 1289 Vcam1 vascular cell adhesion molecule 1 1415989_at chr3 G1|3 50.8 cM 22329 15.5 2 1290 Dip2a /// LOC100044059 DIP2 disco-interacting protein 2 homolog A (Drosophila) 1452908_at chr10 C1|10 41.0 cM 100044059 /// 64451 15.5 2 1291 Hipk3 homeodomain interacting protein kinase 3 1426819_at chr2 E2 15259 15.5 2 1292 Nfib nuclear factor I/B 1434102_at chr4 C4-C6|4 38.6 cM 18028 15.5 2 1293 ----1455970_at ----15.5 2 1294 Maf avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog 1437473_at chr8 E1|8 61.0 cM 17132 15.5 2 1295 Wwtr1 WW domain containing transcription regulator 1 1417818_at chr3 D 97064 15.5 2 1296 Axl AXL receptor tyrosine kinase 1423586_at chr7 A3-B1|7 6.0 cM 26362 15.5 2 1297 Fam19a2 family with sequence similarity 19, member A2 1438007_at chr10 D2 268354 15.5 2 1298 Mfap3l microfibrillar-associated protein 3-like 1428804_at chr8 B3.2 71306 15.5 2 1299 Dcc deleted in colorectal carcinoma 1440487_at chr18 E2|18 45.0 cM 13176 15.5 2 1300 Ramp1 receptor (calcitonin) activity modifying protein 1 1417481_at chr1 D|1 56.0 cM 51801 15.5 2 1301 Colec12 collectin sub-family member 12 1419693_at chr18 A1 140792 15.5 2 1302 Asah2 N-acylsphingosine amidohydrolase 2 1450726_at chr19 C3 54447 15.5 2 1303 Scarf2 scavenger receptor class F, member 2 1434740_at chr16 A3 224024 15.5 2 1304 Sh3bp5 SH3-domain binding protein 5 (BTK-associated) 1421923_at chr14 B 24056 15.5 2 1305 Fam105a family with sequence similarity 105, member A 1435375_at chr15 B1 223433 15.5 2 1306 Tm6sf1 transmembrane 6 superfamily member 1 1424443_at chr7 D1 107769 15.5 2 1307 Adamts9 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 1437785_at chr6 D1 101401 15.5 2 1308 Galnt4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 1455915_at chr10 C3 14426 15.5 2 1309 ----1443124_at ----15.5 2 1310 Cdon cell adhesion molecule-related/down-regulated by oncogenes 1434957_at chr9 A4 57810 15.5 2 1311 Zfp521 zinc finger protein 521 1451332_at chr18 A1 225207 15.5 2 1312 B130021B11Rik RIKEN cDNA B130021B11 gene 1437558_at chr15 A1 320860 15.5 2 1313 Acpl2 acid phosphatase-like 2 1456735_x_at chr9 E3.3 235534 15.5 2 1314 Ltbp3 latent transforming growth factor beta binding protein 3 1438312_s_at chr19 B|19 2.0 cM 16998 15.5 2 1315 Rufy3 RUN and FYVE domain containing 3 1455605_at chr5 E1|5 48.0 cM 52822 15.5 2 1316 Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) 1416094_at chr8 A2|8 8.0 cM 11502 15.5 2 1317 Npnt nephronectin 1452106_at chr3 G3 114249 15.5 2 1318 Bicc1 bicaudal C homolog 1 (Drosophila) 1423484_at chr10 B5.3|10 38.6 cM 83675 15.5 2 1319 Lpar4 lysophosphatidic acid receptor 4 1439665_at chrX D 78134 15.5 2 1320 Gimap4 GTPase, IMAP family member 4 1424375_s_at chr6 B2.3 107526 15.5 2 1321 Slk STE20-like kinase (yeast) 1433999_at chr19 D2 20874 15.5 2 1322 Il18 interleukin 18 1417932_at chr9 A5.3|9 29.0 cM 16173 15.5 2 1323 Upk1b uroplakin 1B 1457065_at chr16 B5-C2 22268 15.5 2 1324 Loxl2 lysyl oxidase-like 2 1431004_at chr14 D2 94352 15.5 2 1325 Ggct gamma-glutamyl cyclotransferase 1435695_a_at chr6 26.0 cM 110175 15.5 2 1326 Ctsk cathepsin K 1450652_at chr3 F2.1|3 47.9 cM 13038 15.5 2 1327 Rab3d RAB3D, member RAS oncogene family 1418891_a_at chr9 A2-A3 19340 15.5 2 1328 Samd4 sterile alpha motif domain containing 4 1424594_at chr14 C1 74480 15.5 2 1329 Slc30a1 solute carrier family 30 (zinc transporter), member 1 1436164_at chr1 H6|1 106.0 cM 22782 15.5 2 1330 Fam19a5 family with sequence similarity 19, member A5 1419490_at chr15 E3 106014 15.5 2 1331 Gpr153 G protein-coupled receptor 153 1426973_at chr4 E2 100129 15.5 2 1332 Crtc3 CREB regulated transcription coactivator 3 1436379_at chr7 D3 70461 15.5 2 1333 2900054C01Rik RIKEN cDNA 2900054C01 gene 1429625_at --73049 15.5 2 1334 Igf1 insulin-like growth factor 1 1434413_at chr10 C1|10 48.0 cM 16000 15.5 2 1335 Col1a2 collagen, type I, alpha 2 1423110_at chr6 A1|6 0.68 cM 12843 15.5 2 1336 Endod1 endonuclease domain containing 1 1426541_a_at chr9 A3 71946 15.5 2 1337 Rrm2b ribonucleotide reductase M2 B (TP53 inducible) 1433773_at chr15 B3.1 382985 15.5 2 1338 Cobll1 Cobl-like 1 1454795_at chr2 C3 319876 15.5 2 1339 Serinc3 serine incorporator 3 1434548_at chr2 H3 26943 15.5 2 1340 Spns2 spinster homolog 2 (Drosophila) 1451601_a_at chr11 B4 216892 15.5 2 1341 Mmp2 matrix metallopeptidase 2 1416136_at chr8 C5|8 44.0 cM 17390 15.5 2 1342 Fgfr1 fibroblast growth factor receptor 1 1424050_s_at chr8 A2|8 10.0 cM 14182 15.5 2 1343 Gltp glycolipid transfer protein 1419027_s_at chr5 F 56356 15.5 2 1344 Wnt5a wingless-related MMTV integration site 5A 1436791_at chr14 A3|14 7.8 cM 22418 15.5 2 1345 Vldlr very low density lipoprotein receptor 1434465_x_at chr19 C1|19 20.0 cM 22359 15.5 2 1346 Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 1444615_x_at chr4 A|4 4.4 cM 12395 15.5 2 1347 Wasl Wiskott-Aldrich syndrome-like (human) 1452193_a_at chr6 A3 73178 15.5 2 1348 Pkd2 polycystic kidney disease 2 1417753_at chr5 E5|5 55.0 cM 18764 15.5 2 1349 9430020K01Rik RIKEN cDNA 9430020K01 gene 1428535_at chr18 A1 240185 15.5 2 1350 Pld1 phospholipase D1 1437113_s_at chr3 A3|3 10.5 cM 18805 15.5 2 1351 Ppl periplakin 1460732_a_at chr16 A-B1|16 4.4 cM 19041 15.5 2 1352 Golim4 golgi integral membrane protein 4 1428875_at chr3 E3 73124 15.5 2 1353 Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 1452714_at chr2 C1.1 66860 15.5 2 1354 Spred1 sprouty protein with EVH-1 domain 1, related sequence 1460116_s_at chr2 E5 114715 15.5 2 1355 Upk1b uroplakin 1B 1435831_at chr16 B5-C2 22268 15.5 2 1356 Sox7 SRY-box containing gene 7 1416564_at chr14 C3 20680 15.5 2 1357 Myo1c myosin IC 1419648_at chr11 C-E1|11 44.13 cM 17913 15.5 2 1358 Cdc42bpg CDC42 binding protein kinase gamma (DMPK-like) 1436197_at chr19 A 240505 15.5 2 1359 Trim33 tripartite motif-containing 33 1455189_at chr3 F2.2 94093 15.5 2 1360 LOC100047484 /// Stxbp3a similar to vesicle transport protein /// syntaxin binding protein 3A 1416653_at chr3 F3 100047484 /// 20912 15.5 2 1361 1110003E01Rik RIKEN cDNA 1110003E01 gene 1435464_at chr5 C3.1 68552 15.5 2 1362 Tgfb3 transforming growth factor, beta 3 1417455_at chr12 D2|12 41.0 cM 21809 15.5 2 1363 Wipi1 WD repeat domain, phosphoinositide interacting 1 1439060_s_at chr11 E1|11 68.0 cM 52639 15.5 2 1364 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 1421679_a_at chr17 A3.3|17 15.23 cM 12575 15.5 2 1365 Casc4 cancer susceptibility candidate 4 1433779_at chr2 E5 319996 15.5 2 1366 Trps1 trichorhinophalangeal syndrome I (human) 1434286_at chr15 C|15 30.1 cM 83925 15.5 2 1367 Cdh11 cadherin 11 1450757_at chr8 D2|8 46.5 cM 12552 15.5 2 1368 Serinc3 serine incorporator 3 1417815_a_at chr2 H3 26943 15.5 2 1369 Klhl2 kelch-like 2, Mayven (Drosophila) 1426978_at chr8 B3.1 77113 15.5 2 1370 Dio2 deiodinase, iodothyronine, type II 1418937_at chr12 D3 13371 15.5 2 1371 March7 membrane-associated ring finger (C3HC4) 7 1420609_at chr2 C3 57438 15.5 2 1372 Ptplad2 protein tyrosine phosphatase-like A domain containing 2 1450967_at chr4 C4 66775 15.5 2 1373 Magee1 melanoma antigen, family E, 1 1422431_at chrX C3 107528 15.5 2 1374 Fbln2 fibulin 2 1423407_a_at chr6 D|6 37.2 cM 14115 15.5 2 1375 Leprel2 leprecan-like 2 1449531_at chr6 F2|6 60.19 cM 14789 15.5 2 1376 Sulf1 sulfatase 1 1436319_at chr1 A3 240725 15.5 2 1377 Ovol1 OVO homolog-like 1 (Drosophila) 1419051_at chr19 A 18426 15.5 2 1378 Ar androgen receptor 1422982_at chrX C3|X 36.0 cM 11835 15.5 2 1379 Msn moesin 1421814_at chrX C3 17698 15.5 2 1380 Dynlt3 dynein light chain Tctex-type 3 1459854_s_at chrX A1.1 67117 15.5 2 1381 Fut11 fucosyltransferase 11 1434123_at chr14 B 73068 15.5 2 1382 Klf4 Kruppel-like factor 4 (gut) 1417394_at chr4 B3|4 19.7 cM 16600 15.5 2 1383 Myo1b myosin IB 1459679_s_at chr1 C1.1|1 24.8 cM 17912 15.5 2 1384 Ptgfrn prostaglandin F2 receptor negative regulator 1434891_at chr3 F3 19221 15.5 2 1385 Ndrg1 N-myc downstream regulated gene 1 1420760_s_at chr15 D2 17988 15.5 2 1386 Ablim1 actin-binding LIM protein 1 1453103_at chr19 D2|19 53.0 cM 226251 15.5 2 1387 Col8a1 collagen, type VIII, alpha 1 1455627_at chr16 C1.1 12837 15.5 2 1388 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1422518_at chrX A1.1|X 4.2 cM 12361 15.5 2 1389

PAGE 14

Foxo3 forkhead box O3 1434831_a_at chr10 B2|10 30.0 cM 56484 15.5 2 1390 Chst11 /// Phactr1 carbohydrate sulfotransferase 11 /// phosphatase and actin regulator 1 1456606_a_at chr10 C1 /// chr13 A4 218194 /// 58250 15.5 2 1391 Ssfa2 sperm specific antigen 2 1423613_at chr2 D 70599 15.5 2 1392 Pak3 p21 protein (Cdc42/Rac)-activated kinase 3 1435486_at chrX F2 18481 15.5 2 1393 Pcdh7 protocadherin 7 1456214_at chr5 C3-D 54216 15.5 2 1394 Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 1418340_at chr1 H3|1 93.3 cM 14127 15.5 2 1395 Ltbp1 latent transforming growth factor beta binding protein 1 1448870_at chr17 E3 268977 15.5 2 1396 Taf9b TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor 1434960_at chrX D 407786 15.5 2 1397 Socs6 suppressor of cytokine signaling 6 1435492_at chr18 E4 54607 15.5 2 1398 Degs1 degenerative spermatocyte homolog 1 (Drosophila) 1423346_at chr1 H5 13244 15.5 2 1399 Upk1b uroplakin 1B 1455464_x_at chr16 B5-C2 22268 15.5 2 1400 Sec23a SEC23A (S. cerevisiae) 1423347_at chr12 C1 20334 15.5 2 1401 Pls3 plastin 3 (T-isoform) 1423725_at chrX A7.3 102866 15.5 2 1402 Pdzrn3 PDZ domain containing RING finger 3 1416846_a_at chr6 D3 55983 15.5 2 1403 Sepp1 selenoprotein P, plasma, 1 1452141_a_at chr15 A1|15 5.9 cM 20363 15.5 2 1404 Col5a2 collagen, type V, alpha 2 1422437_at chr1 C1 12832 15.5 2 1405 Sstr4 somatostatin receptor 4 1457440_at chr2 G3|2 84.0 cM 20608 15.5 2 1406 Irs1 insulin receptor substrate 1 1423104_at chr1 C5|1 57.0 cM 16367 15.5 2 1407 Atl3 Atlastin GTPase 3 1436389_at chr19 A 109168 15.5 2 1408 Gstt1 glutathione S-transferase, theta 1 1418186_at chr10 B5-C1|10 40.7 cM 14871 15.5 2 1409 Rab8b RAB8B, member RAS oncogene family 1426799_at chr9 C 235442 15.5 2 1410 Dab2 disabled homolog 2 (Drosophila) 1420498_a_at chr15 A|15 6.7 cM 13132 15.5 2 1411 Hs3st1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 1423450_a_at chr5 B3|5 22.0 cM 15476 15.5 2 1412 Cnrip1 cannabinoid receptor interacting protein 1 1433695_at chr11 A3.1 380686 15.5 2 1413 Cbx6 chromobox homolog 6 1424407_s_at chr15 E1 494448 15.5 2 1414 Mef2a myocyte enhancer factor 2A 1427186_a_at chr7 C|7 33.0 cM 17258 15.5 2 1415 Zdhhc14 zinc finger, DHHC domain containing 14 1438975_x_at chr17 A1 224454 15.5 2 1416 Bche butyrylcholinesterase 1436098_at chr3 E3 12038 15.5 2 1417 Emp3 epithelial membrane protein 3 1417104_at chr7 B4|7 24.5 cM 13732 15.5 2 1418 Lgi2 leucine-rich repeat LGI family, member 2 1440147_at chr5 C1 246316 15.5 2 1419 ----1443952_at ----15.5 2 1420 Rps6ka5 ribosomal protein S6 kinase, polypeptide 5 1440343_at chr12 E 73086 15.5 2 1421 Fech ferrochelatase 1449181_at chr18 E1|18 39.0 cM 14151 15.5 2 1422 Atp11a ATPase, class VI, type 11A 1456388_at chr8 A2 50770 15.5 2 1423 Il1rap interleukin 1 receptor accessory protein 1421844_at chr16 B2 16180 15.5 2 1424 Fam102b family with sequence similarity 102, member B 1434828_at chr3 F3 329739 15.5 2 1425 Lphn3 latrophilin 3 1428523_at chr5 D-E1 319387 15.5 2 1426 Lyst lysosomal trafficking regulator 1434674_at chr13 A1|13 7.0 cM 17101 15.5 2 1427 S1pr3 sphingosine-1-phosphate receptor 3 1438658_a_at chr13 B1 13610 15.5 2 1428 Wnt5a wingless-related MMTV integration site 5A 1448818_at chr14 A3|14 7.8 cM 22418 15.5 2 1429 Rab25 RAB25, member RAS oncogene family 1417738_at chr3 E3-F1 53868 15.5 2 1430 H2-D1 histocompatibility 2, D region locus 1 1451784_x_at chr17 B1|17 19.09 cM 14964 15.5 2 1431 Tubb2a tubulin, beta 2A 1427347_s_at chr13 A3.3|13 16.0 cM 22151 15.5 2 1432 Cugbp2 CUG triplet repeat, RNA binding protein 2 1423895_a_at chr2 A2-A3 14007 15.5 2 1433 Jun Jun oncogene 1448694_at chr4 C5-C7|4 44.6 cM 16476 15.5 2 1434 Rbpj recombination signal binding protein for immunoglobulin kappa J region 1454896_at chr5 C1-C3|5 37.5 cM 19664 15.5 2 1435 Pkd2 polycystic kidney disease 2 1441870_s_at chr5 E5|5 55.0 cM 18764 15.5 2 1436 Krt15 keratin 15 1422667_at chr11 D|11 58.5 cM 16665 15.5 2 1437 Nipal1 NIPA-like domain containing 1 1456321_at chr5 C3.2 70701 15.5 2 1438 Fam129b family with sequence similarity 129, member B 1426812_a_at chr2 B 227737 15.5 2 1439 Spats2l spermatogenesis associated, serine-rich 2-like 1455566_s_at chr1 C2 67198 15.5 2 1440 Slu7 SLU7 splicing factor homolog (S. cerevisiae) 1425487_at chr11 A5-B1.1 193116 15.5 2 1441 Irs2 insulin receptor substrate 2 1443969_at chr8 A1.1 384783 15.5 2 1442 Gm10664 predicted gene 10664 1436287_at --100038489 15.5 2 1443 Esf1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1453727_at chr2 G3 66580 15.5 2 1444 Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 1427640_a_at chr4 A|4 4.4 cM 12395 15.5 2 1445 Scpep1 serine carboxypeptidase 1 1455908_a_at chr11 C 74617 15.5 2 1446 Anxa4 annexin A4 1424176_a_at chr6 D1|6 38.0 cM 11746 15.5 2 1447 Anxa5 annexin A5 1425567_a_at chr3 B|3 19.2 cM 11747 15.5 2 1448 Reep1 receptor accessory protein 1 1433509_s_at chr6 C1|6 31.5 cM 52250 15.5 2 1449 Ehbp1 EH domain binding protein 1 1424586_at chr11 A3.2|11 11.0 cM 216565 15.5 2 1450 LOC100044115 /// Rin2 similar to Ras and Rab interactor 2 /// Ras and Rab interactor 2 1426368_at chr2 G1 100044115 /// 74030 15.5 2 1451 Vat1 vesicle amine transport protein 1 homolog (T californica) 1438165_x_at chr11 D 26949 15.5 2 1452 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1451152_a_at chr1 H2.2|1 86.8 cM 11931 15.5 2 1453 Sgk1 serum/glucocorticoid regulated kinase 1 1416041_at chr10 A3 20393 15.5 2 1454 Shox2 short stature homeobox 2 1438042_at chr3 E3-F1|3 31.6 cM 20429 15.5 2 1455 Tbx18 T-box18 1429974_at chr9 E3.2|9 48.5 cM 76365 15.5 2 1456 Osr1 odd-skipped related 1 (Drosophila) 1449350_at chr12 A1.1|12 1.0 cM 23967 15.5 2 1457 Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 1457700_at chr17 B1 320997 15.5 2 1458 Ptx3 pentraxin related gene 1418666_at chr3 E1|3 33.8 cM 19288 15.5 2 1459 ----1456778_at ----15.5 2 1460 Cast calpastatin 1451413_at chr13 C1 12380 15.5 2 1461 Blnk B-cell linker 1451780_at chr19 C3|19 31.0 cM 17060 15.5 2 1462 Hs3st4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 1455620_at chr7 F3 628779 15.5 2 1463 Vsnl1 visinin-like 1 1420955_at chr12 A2 26950 15.5 2 1464 Etv1 ets variant gene 1 1450684_at chr12 A3-B1|12 18.5 cM 14009 15.5 2 1465 Mef2a myocyte enhancer factor 2A 1421252_a_at chr7 C|7 33.0 cM 17258 15.5 2 1466 Mgst2 microsomal glutathione S-transferase 2 1452592_at chr3 C 211666 15.5 2 1467 Tuba4a tubulin, alpha 4A 1417374_at chr1 C3 22145 15.5 2 1468 Timp3 tissue inhibitor of metalloproteinase 3 1449335_at chr10 C1|10 C1-D1|10 47.0 cM 21859 15.5 2 1469 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 1424638_at chr17 A3.3|17 15.23 cM 12575 15.5 2 1470 Mcc mutated in colorectal cancers 1438081_at chr18 B3|18 21.0 cM 328949 15.5 2 1471 Hpse heparanase 1433930_at chr5 E4 15442 15.5 2 1472 Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 1421074_at chr3 A1|3 1.0 cM 13123 15.5 2 1473 ----1440325_at ----15.5 2 1474 Fermt3 fermitin family homolog 3 (Drosophila) 1456014_s_at chr19 A 108101 15.5 2 1475 Jun Jun oncogene 1417409_at chr4 C5-C7|4 44.6 cM 16476 15.5 2 1476 Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1433561_at chr16 B2 78618 15.5 2 1477 ----1434848_at ----15.5 2 1478 Cldn1 claudin 1 1437932_a_at chr16 B2 12737 15.5 2 1479 Pdlim3 PDZ and LIM domain 3 1449178_at chr8 B1.1 53318 15.5 2 1480 C730049O14Rik RIKEN cDNA C730049O14 gene 1435084_at --320117 15.5 2 1481 ----1440527_at ----15.5 2 1482 Mapre2 microtubule-associated protein, RP/EB family, member 2 1451989_a_at chr18 A2 212307 15.5 2 1483 Ptrf polymerase I and transcript release factor 1424130_a_at chr11 D|11 60.5 cM 19285 15.5 2 1484 Rpgr /// Srpx retinitis pigmentosa GTPase regulator /// sushi-repeat-containing protein 1451939_a_at chrX A1.1 /// chrX A1.2 19893 /// 51795 15.5 2 1485 ----1427195_at ----15.5 2 1486 Cpd carboxypeptidase D 1455009_at chr11 B5|11 46.0 cM 12874 15.5 2 1487 ----1436614_at ----15.5 2 1488 Dab2 disabled homolog 2 (Drosophila) 1423805_at chr15 A|15 6.7 cM 13132 15.5 2 1489 Fzd1 frizzled homolog 1 (Drosophila) 1437284_at chr5 A1|5 5.0 cM 14362 15.5 2 1490 ----1460632_at ----15.5 2 1491 Arhgap24 Rho GTPase activating protein 24 1424842_a_at chr5 E4 231532 15.5 2 1492 Timp3 tissue inhibitor of metalloproteinase 3 1419089_at chr10 C1|10 C1-D1|10 47.0 cM 21859 15.5 2 1493 Hspb6 heat shock protein, alpha-crystallin-related, B6 1436332_at chr7 B1 243912 15.5 2 1494 Sptlc3 serine palmitoyltransferase, long chain base subunit 3 1439492_at chr2 F3 228677 15.5 2 1495 1810011O10Rik RIKEN cDNA 1810011O10 gene 1451415_at chr8 A2 69068 15.5 2 1496

PAGE 15

Runx2 runt related transcription factor 2 1424704_at chr17 B3|17 28.07 cM 12393 15.5 2 1497 Jazf1 JAZF zinc finger 1 1433894_at chr6 B3|6 25.9 cM 231986 15.5 2 1498 Spnb2 spectrin beta 2 1444089_at chr11 A3.3|11 13.0 cM 20742 15.5 2 1499 Vat1 vesicle amine transport protein 1 homolog (T californica) 1423726_at chr11 D 26949 15.5 2 1500 Stard5 StAR-related lipid transfer (START) domain containing 5 1450769_s_at chr7 D3 170460 15.5 2 1501 Npl N-acetylneuraminate pyruvate lyase 1424265_at chr1 G2 74091 15.5 2 1502 Mef2c myocyte enhancer factor 2C 1424852_at chr13 C3|13 45.0 cM 17260 15.5 2 1503 Gucy1a3 guanylate cyclase 1, soluble, alpha 3 1434141_at chr3 E3 60596 15.5 2 1504 Plxnd1 plexin D1 1451475_at chr6 E3 67784 15.5 2 1505 9230105E10Rik RIKEN cDNA 9230105E10 gene 1443858_at chr7 E3 319236 15.5 2 1506 Metrnl meteorin, glial cell differentiation regulator-like 1424356_a_at chr11 E2 210029 15.5 2 1507 Clu /// LOC100046120 clusterin /// similar to clusterin 1454849_x_at chr14 D1|14 28.0 cM 100046120 /// 12759 15.5 2 1508 Adcy7 adenylate cyclase 7 1456307_s_at chr8 C3|8 40.0 cM 11513 15.5 2 1509 Mylip myosin regulatory light chain interacting protein 1424988_at chr13 A5 218203 15.5 2 1510 Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha 1455091_at chr9 E4 235542 15.5 2 1511 Fndc3b fibronectin type III domain containing 3B 1433833_at chr3 A3 72007 15.5 2 1512 Myadm myeloid-associated differentiation marker 1439389_s_at chr7 A1|7 4.0 cM 50918 15.5 2 1513 Elovl7 ELOVL family member 7, elongation of long chain fatty acids (yeast) 1441891_x_at chr13 D2.1 74559 15.5 2 1514 Ar androgen receptor 1455647_at chrX C3|X 36.0 cM 11835 15.5 2 1515 Sh3kbp1 SH3-domain kinase binding protein 1 1460337_at chrX F4 58194 15.5 2 1516 Bglap-rs1 /// Bglap1 /// Bglap2 bone gamma-carboxyglutamate protein, related sequence 1 1449880_s_at chr3 F1|3 42.6 cM 12095 /// 12096 /// 12097 15.5 2 1517 2210012G02Rik RIKEN cDNA 2210012G02 gene 1431067_at chr4 C7 66526 15.5 2 1518 Tshz2 teashirt zinc finger family member 2 1435385_at chr2 H3|2 99.0 cM 228911 15.5 2 1519 Aplnr apelin receptor 1438651_a_at chr2 E1 23796 15.5 2 1520 Pdgfrb platelet derived growth factor receptor, beta polypeptide 1436970_a_at chr18 E1|18 30.0 cM 18596 15.5 2 1521 1110067D22Rik RIKEN cDNA 1110067D22 gene 1451313_a_at chr11 A3.1|11 11.0 cM 216551 15.5 2 1522 Gng12 guanine nucleotide binding protein (G protein), gamma 12 1455089_at chr6 C1|6 30.0 cM 14701 15.5 2 1523 Mcam melanoma cell adhesion molecule 1416357_a_at chr9 A5.1 84004 15.5 2 1524 Cd93 CD93 antigen 1456046_at chr2 G3|2 84.0 cM 17064 15.5 2 1525 Tshz1 teashirt zinc finger family member 1 1427233_at chr18 E4|18 56.0 cM 110796 15.5 2 1526 Mapre2 microtubule-associated protein, RP/EB family, member 2 1451990_at chr18 A2 212307 15.5 2 1527 Lgals9 lectin, galactose binding, soluble 9 1421217_a_at chr11 B5 16859 15.5 2 1528 Lmna lamin A 1425472_a_at chr3 F1|3 42.6 cM 16905 15.5 2 1529 Rdh12 retinol dehydrogenase 12 1424256_at chr12 D2 77974 15.5 2 1530 Ssbp2 single-stranded DNA binding protein 2 1438423_at chr13 C3 66970 15.5 2 1531 Cxcl12 chemokine (C-X-C motif) ligand 12 1448823_at chr6 F1|6 53.0 cM 20315 15.5 2 1532 Ppp3cc protein phosphatase 3, catalytic subunit, gamma isoform 1420743_a_at chr14 D2 19057 15.5 2 1533 Aqp3 aquaporin 3 1422008_a_at --11828 15.5 2 1534 1110059G02Rik RIKEN cDNA 1110059G02 gene 1436204_at --68786 15.5 2 1535 Mark1 MAP/microtubule affinity-regulating kinase 1 1425510_at chr1 H5 226778 15.5 2 1536 Ndrg1 N-myc downstream regulated gene 1 1456174_x_at chr15 D2 17988 15.5 2 1537 Vat1 Vesicle amine transport protein 1 homolog (T californica) 1441930_x_at chr11 D 26949 15.5 2 1538 Ets1 E26 avian leukemia oncogene 1, 5' domain 1452163_at chr9 A4|9 15.0 cM 23871 15.5 2 1539 5430421F17Rik RIKEN cDNA 5430421F17 gene 1430239_at --74489 15.5 2 1540 Nr3c2 nuclear receptor subfamily 3, group C, member 2 1435991_at chr8 C1|8 35.0 cM 110784 15.5 2 1541 Stim2 stromal interaction molecule 2 1441024_at chr5 C1|5 34.0 cM 116873 15.5 2 1542 Fcgr1 Fc receptor, IgG, high affinity I 1417876_at chr3 F2.1|3 45.2 cM 14129 15.5 2 1543 Slain1 SLAIN motif family, member 1 1424824_at chr14 E2.3 105439 15.5 2 1544 Nqo2 NAD(P)H dehydrogenase, quinone 2 1436189_at chr13 A4|13 13.8 cM 18105 15.5 2 1545 Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 1456609_at chr4 D3 66259 15.5 2 1546 Nipal4 NIPA-like domain containing 4 1441909_s_at chr11 B1.1 214112 15.5 2 1547 Col6a2 collagen, type VI, alpha 2 1426947_x_at chr10 41.1 cM 12834 15.5 2 1548 Dpysl3 dihydropyrimidinase-like 3 1454613_at chr18 B3 22240 15.5 2 1549 CU041261.1 /// LOC100189605 /// Mup1 /// Mup10 /// Mup12 /// Mup2 /// Mup7 // major urinary protein LOC100048885 1420465_s_at chr4 B3 /// chr4 B3|4 /// chr4 B3|4 27.8 cM 100039008 /// 100039054 /// 100041658 /// 100041687 /// 100048885 /// 1001 15.5 2 1550 Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1435078_at chr11 E1 77097 15.5 2 1551 Emcn endomucin 1425582_a_at chr3 G3 59308 15.5 2 1552 Ncam1 neural cell adhesion molecule 1 1426865_a_at chr9 A5.3|9 28.0 cM 17967 15.5 2 1553 Nt5e 5' nucleotidase, ecto 1428547_at chr9 E3.2 23959 15.5 2 1554 Ppap2b phosphatidic acid phosphatase type 2B 1448908_at chr4 C6|4 52.7 cM 67916 15.5 2 1555 Mfsd6 major facilitator superfamily domain containing 6 1424464_s_at chr1 C1.1 98682 15.5 2 1556 Fgd5 FYVE, RhoGEF and PH domain containing 5 1460578_at chr6 D1 232237 15.5 2 1557 Pja2 praja 2, RING-H2 motif containing 1427148_at chr17 E1.1 224938 15.5 2 1558 C1qb complement component 1, q subcomponent, beta polypeptide 1437726_x_at chr4 D3|4 66.1 cM 12260 15.5 2 1559 ----1442257_at ----15.5 2 1560 Krt19 keratin 19 1417156_at chr11 D|11 58.51 cM 16669 15.5 2 1561 Col23a1 collagen, type XXIII, alpha 1 1440911_at chr11 B1.3 237759 15.5 2 1562 Atp13a4 /// LOC637970 ATPase type 13A4 /// similar to type V P-type ATPase isoform 4 1438707_at chr16 B2 224079 /// 637970 15.5 2 1563 Id4 /// LOC100045546 inhibitor of DNA binding 4 /// similar to Id4 1423259_at chr13 B|13 31.0 cM 100045546 /// 15904 15.5 2 1564 Serpinb6c serine (or cysteine) peptidase inhibitor, clade B, member 6c 1451594_s_at chr13 A3.3|13 13.6 cM 97848 15.5 2 1565 Wnt2 wingless-related MMTV integration site 2 1449425_at chr6 4.2 cM 22413 15.5 2 1566 Ap1s2 adaptor-related protein complex 1, sigma 2 subunit 1452657_at chrX F5 108012 15.5 2 1567 Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 1425676_a_at chr4 D2.1 54325 15.5 2 1568 Tcp11l2 t-complex 11 (mouse) like 2 1454646_at chr10 C1 216198 15.5 2 1569 Ncf1 neutrophil cytosolic factor 1 1456772_at chr5 G2|5 74.0 cM 17969 15.5 2 1570 Eps8 /// LOC632638 epidermal growth factor receptor pathway substrate 8 1422823_at chr6 G1|6 66.0 cM 13860 /// 632638 15.5 2 1571 Rgs3 regulator of G-protein signaling 3 1425701_a_at chr4 B3|4 35.0 cM 50780 15.5 2 1572 Negr1 neuronal growth regulator 1 1456392_at chr3 H4 320840 15.5 2 1573 Maf avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog 1456060_at chr8 E1|8 61.0 cM 17132 15.5 2 1574 Ets1 E26 avian leukemia oncogene 1, 5' domain 1426725_s_at chr9 A4|9 15.0 cM 23871 15.5 2 1575 Nrxn1 neurexin I 1454691_at chr17 E5 18189 15.5 2 1576 Matn2 matrilin 2 1455978_a_at chr15 B3.3 17181 15.5 2 1577 Myadm myeloid-associated differentiation marker 1423321_at chr7 A1|7 4.0 cM 50918 15.5 2 1578 Gsn gelsolin 1437171_x_at chr2 B|2 24.5 cM 227753 15.5 2 1579 Sorcs1 VPS10 domain receptor protein SORCS 1 1425864_a_at chr19 D2|19 51.0 cM 58178 15.5 2 1580 1110018F16Rik RIKEN cDNA 1110018F16 gene 1429468_at --68594 15.5 2 1581 Cugbp2 CUG triplet repeat, RNA binding protein 2 1451154_a_at chr2 A2-A3 14007 15.5 2 1582 Pdlim5 PDZ and LIM domain 5 1427475_a_at chr3 H3 56376 15.5 2 1583 Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 1453134_at chr3 B|3 12.4 cM 18706 15.5 2 1584 Epdr1 ependymin related protein 1 (zebrafish) 1450380_at chr13 A2 105298 15.5 2 1585 Cpeb2 cytoplasmic polyadenylation element binding protein 2 1434272_at chr5 B 231207 15.5 2 1586 Fkbp10 FK506 binding protein 10 1449632_s_at chr11 D|11 58.0 cM 14230 15.5 2 1587 Gsn gelsolin 1415812_at chr2 B|2 24.5 cM 227753 15.5 3 1588 Sdpr serum deprivation response 1416778_at chr1 C1.1 20324 15.5 3 1589 Mef2c myocyte enhancer factor 2C 1421028_a_at chr13 C3|13 45.0 cM 17260 15.5 3 1590 Glrx glutaredoxin 1416593_at chr13 C1|13 44.0 cM 93692 15.5 3 1591 Armcx3 armadillo repeat containing, X-linked 3 1460359_at chrX E3 71703 15.5 3 1592 1110059G02Rik RIKEN cDNA 1110059G02 gene 1436203_a_at --68786 15.5 3 1593 Pde2a phosphodiesterase 2A, cGMP-stimulated 1452202_at chr7 E3 207728 15.5 3 1594 Fmo1 flavin containing monooxygenase 1 1417429_at chr1 H1|1 92.6 cM 14261 15.5 3 1595 Tgfbr2 transforming growth factor, beta receptor II 1426397_at chr9 F3|9 69.0 cM 21813 15.5 3 1596 Bcl2 B-cell leukemia/lymphoma 2 1457687_at chr1 E2.1|1 59.8 cM 12043 15.5 3 1597 Nfe2l3 nuclear factor, erythroid derived 2, like 3 1417520_at chr6 B3|6 25.5 cM 18025 15.5 3 1598 Hspa1b heat shock protein 1B 1427126_at chr17 B1|17 18.9 cM 15511 15.5 3 1599 Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1430526_a_at chr19 C1|19 17.0 cM 67155 15.5 3 1600 Col6a2 collagen, type VI, alpha 2 1452250_a_at chr10 41.1 cM 12834 15.5 3 1601 Hopx HOP homeobox 1451776_s_at chr5 C3.3 74318 15.5 3 1602 Myo18a myosin XVIIIA 1451422_at chr11 B5 360013 15.5 3 1603

PAGE 16

Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 1455994_x_at chr4 D2.1 54325 15.5 3 1604 Nr3c1 nuclear receptor subfamily 3, group C, member 1 1457635_s_at chr18 B3|18 20.0 cM 14815 15.5 3 1605 Kitl kit ligand 1415855_at chr10 D1|10 57.0 cM 17311 15.5 3 1606 Zbtb7b zinc finger and BTB domain containing 7B 1455071_at chr3 A1-A2|3 45.0 cM 22724 15.5 3 1607 Ap1s2 adaptor-related protein complex 1, sigma 2 subunit 1447903_x_at chrX F5 108012 15.5 3 1608 Igfbp7 insulin-like growth factor binding protein 7 1423584_at chr5 C3.3 29817 15.5 3 1609 Glrx glutaredoxin 1416592_at chr13 C1|13 44.0 cM 93692 15.5 3 1610 Slc4a3 solute carrier family 4 (anion exchanger), member 3 1418485_at chr1 C4|1 41.0 cM 20536 15.5 3 1611 Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 1456530_x_at chr4 D2.1 54325 15.5 3 1612 Pdzk1ip1 PDZK1 interacting protein 1 1417689_a_at chr4 D1 67182 15.5 3 1613 Tmem40 transmembrane protein 40 1441917_s_at chr6 E3 94346 15.5 3 1614 Col1a1 collagen, type I, alpha 1 1455494_at chr11 D|11 56.0 cM 12842 15.5 3 1615 Actr1b ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 1452057_at chr1 B 226977 15.5 3 1616 Fabp4 fatty acid binding protein 4, adipocyte 1417023_a_at chr3 A1|3 13.9 cM 11770 15.5 3 1617 Fap fibroblast activation protein 1417552_at chr2 C1.3|2 36.0 cM 14089 15.5 3 1618 Wif1 Wnt inhibitory factor 1 1425425_a_at chr10 D2 24117 15.5 3 1619 Eppk1 epiplakin 1 1427537_at chr15 D3 223650 15.5 3 1620 ----1442157_at ----15.5 3 1621 Lyz1 lysozyme 1 1436996_x_at chr10 D2 17110 15.5 3 1622 Ugt1a1 /// Ugt1a10 /// Ugt1a2 /// Ugt1a5 /// Ugt1a6a /// Ugt1a6b /// Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A1 1424783_a_at chr1 D /// chr1 D|1 51.7 cM 22236 /// 394430 /// 394432 /// 394433 /// 394434 /// 394435 /// 394436 // 15.5 3 1623 Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 1453055_at chr2 F1 214968 15.5 3 1624 Tgfbi transforming growth factor, beta induced 1415871_at chr13 38.0 cM 21810 15.5 3 1625 Tnfsf12 /// Tnfsf12-tnfsf13 /// Tnfsf13 tumor necrosis factor (ligand) superfamily, member 12 1418345_at chr11 B4 21944 /// 619441 /// 69583 15.5 3 1626 Mrc1 mannose receptor, C type 1 1450430_at chr2 A2|2 5.0 cM 17533 15.5 3 1627 Pthlh parathyroid hormone-like peptide 1422324_a_at chr6 F-G|6 74.0 cM 19227 15.5 3 1628 Ugt1a1 /// Ugt1a10 /// Ugt1a2 /// Ugt1a5 /// Ugt1a6a /// Ugt1a6b /// Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A1 1426261_s_at chr1 D /// chr1 D|1 51.7 cM 22236 /// 394430 /// 394432 /// 394433 /// 394434 /// 394435 /// 394436 // 15.5 3 1629 Itpkb inositol 1,4,5-trisphosphate 3-kinase B 1435272_at chr1 H5|1 100.0 cM 320404 15.5 3 1630 Lmna lamin A 1457670_s_at chr3 F1|3 42.6 cM 16905 15.5 3 1631 ----1456539_at ----15.5 3 1632 Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 1417416_at chr6 F1-F3|6 61.0 cM 16485 15.5 3 1633 Tgm2 transglutaminase 2, C polypeptide 1455900_x_at chr2 H1|2 89.0 cM 21817 15.5 3 1634 Rtp4 receptor transporter protein 4 1418580_at chr16 B1 67775 15.5 3 1635 Itih5 inter-alpha (globulin) inhibitor H5 1429159_at chr2 A1 209378 15.5 3 1636 Eln elastin 1420855_at chr5 G2|5 75.0 cM 13717 15.5 3 1637 Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1422648_at chr8 A4|8 21.0 cM 11988 15.5 3 1638 Pafah2 platelet-activating factor acetylhydrolase 2 1448489_at chr4 D3 100163 15.5 3 1639 Col5a2 collagen, type V, alpha 2 1450625_at chr1 C1 12832 15.5 3 1640 Elf5 E74-like factor 5 1419555_at chr2 E3 13711 15.5 3 1641 Pcdh10 protocadherin 10 1430667_at chr3 C 18526 15.5 3 1642 Egr3 early growth response 3 1436329_at chr14 D2 13655 15.5 3 1643 Cpeb4 cytoplasmic polyadenylation element binding protein 4 1420618_at chr11 A4 67579 15.5 3 1644 Zfp385b zinc finger protein 385B 1436731_at chr2 C3 241494 15.5 3 1645 Bend6 BEN domain containing 6 1434590_at chr1 B 320705 15.5 3 1646 Sox18 SRY-box containing gene 18 1449135_at chr2 H4|2 96.0 cM 20672 15.5 3 1647 Bgn biglycan 1416405_at chrX B|X 29.3 cM 12111 15.5 3 1648 Clu /// LOC100046120 clusterin /// similar to clusterin 1437458_x_at chr14 D1|14 28.0 cM 100046120 /// 12759 15.5 3 1649 Clic3 chloride intracellular channel 3 1429574_at chr2 A3 69454 15.5 3 1650 Cryab crystallin, alpha B 1416455_a_at chr9 A5.3|9 29.0 cM 12955 15.5 3 1651 Bicc1 bicaudal C homolog 1 (Drosophila) 1441137_at chr10 B5.3|10 38.6 cM 83675 15.5 3 1652 Fosl2 /// LOC634417 fos-like antigen 2 /// similar to fos-like antigen 2 1437247_at chr5 B1|5 18.1 cM 14284 /// 634417 15.5 3 1653 Nxph1 neurexophilin 1 1436718_at chr6 A1 18231 15.5 3 1654 B130021B11Rik RIKEN cDNA B130021B11 gene 1438989_s_at chr15 A1 320860 15.5 3 1655 Pacsin3 protein kinase C and casein kinase substrate in neurons 3 1416995_at chr2 E1 80708 15.5 3 1656 S100a4 S100 calcium binding protein A4 1424542_at chr3 F1-F2|3 43.6 cM 20198 15.5 3 1657 C1qtnf6 C1q and tumor necrosis factor related protein 6 1431856_a_at chr15 E1 72709 15.5 3 1658 Cav1 caveolin 1, caveolae protein 1449145_a_at chr6 A2 12389 15.5 3 1659 Ptpn6 protein tyrosine phosphatase, non-receptor type 6 1460188_at chr6 F2|6 60.22 cM 15170 15.5 3 1660 Tuba4a tubulin, alpha 4A 1417373_a_at chr1 C3 22145 15.5 3 1661 Tprg transformation related protein 63 regulated 1430114_at chr16 B1 71338 15.5 3 1662 Plekha5 pleckstrin homology domain containing, family A member 5 1425543_s_at chr6 G2 109135 15.5 3 1663 Col6a1 collagen, type VI, alpha 1 1448590_at chr10 41.1 cM 12833 15.5 3 1664 Clu /// LOC100046120 clusterin /// similar to clusterin 1437689_x_at chr14 D1|14 28.0 cM 100046120 /// 12759 15.5 3 1665 Clu /// LOC100046120 clusterin /// similar to clusterin 1418626_a_at chr14 D1|14 28.0 cM 100046120 /// 12759 15.5 3 1666 Col14a1 collagen, type XIV, alpha 1 1427168_a_at chr15 D 12818 15.5 3 1667 Sdpr serum deprivation response 1416779_at chr1 C1.1 20324 15.5 3 1668 AF529169 cDNA sequence AF529169 1437501_at chr9 E3.1 209743 15.5 3 1669 Reck reversion-inducing-cysteine-rich protein with kazal motifs 1450784_at chr4 B1 53614 15.5 3 1670 Ndufa4l2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 1434905_at chr10 D3 407790 15.5 3 1671 Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1416868_at chr4 C7|4 24.7 cM 12580 15.5 3 1672 Nfe2l3 nuclear factor, erythroid derived 2, like 3 1453614_a_at chr6 B3|6 25.5 cM 18025 15.5 3 1673 Csf1r colony stimulating factor 1 receptor 1419872_at chr18 D|18 30.0 cM 12978 15.5 3 1674 Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3 1419225_at chr14 B 12294 15.5 3 1675 Ephx1 epoxide hydrolase 1, microsomal 1422438_at chr1 H4|1 98.5 cM 13849 15.5 3 1676 Zeb2 zinc finger E-box binding homeobox 2 1434298_at chr2 C1 24136 15.5 3 1677 Nfix nuclear factor I/X 1436364_x_at chr8 C1-C2|8 38.6 cM 18032 15.5 3 1678 Lmna lamin A 1421654_a_at chr3 F1|3 42.6 cM 16905 15.5 3 1679 Acsl1 acyl-CoA synthetase long-chain family member 1 1450643_s_at chr8 B2 14081 15.5 3 1680 Pcdh9 protocadherin 9 1429861_at chr14 E2.1 211712 15.5 3 1681 Ldb2 LIM domain binding 2 1456786_at chr5 B3 16826 15.5 3 1682 Col8a2 collagen, type VIII, alpha 2 1434667_at chr4 D2.2 329941 15.5 3 1683 Nudt6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 1456945_at chr3 B 229228 15.5 3 1684 Sim1 single-minded homolog 1 (Drosophila) 1449967_at chr10 B3|10 26.5 cM 20464 15.5 3 1685 Egln3 EGL nine homolog 3 (C. elegans) 1418649_at chr12 C1 112407 15.5 3 1686 ----1439906_at ----15.5 3 1687 LOC100045546 similar to Id4 1450928_at --100045546 15.5 3 1688 Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 1433825_at chr7 D3|7 39.0 cM 18213 15.5 3 1689 Egfl6 EGF-like-domain, multiple 6 1419332_at chrX F5|X 71.5 cM 54156 15.5 3 1690 Nrp1 neuropilin 1 1448943_at chr8 E|8 73.0 cM 18186 15.5 3 1691 Fstl3 follistatin-like 3 1422803_at chr10 C1 83554 15.5 3 1692 Nr3c1 nuclear receptor subfamily 3, group C, member 1 1460303_at chr18 B3|18 20.0 cM 14815 15.5 3 1693 Ckmt1 creatine kinase, mitochondrial 1, ubiquitous 1432418_a_at chr2 F1-F3|2 67.6 cM 12716 15.5 3 1694 BC062109 cDNA sequence BC062109 1436656_at chr5 E4 231503 15.5 3 1695 Itga8 integrin alpha 8 1454966_at chr2 A1 241226 15.5 3 1696 Wnt9a wingless-type MMTV integration site 9A 1436978_at chr11 B1.3 216795 15.5 3 1697 Capn1 calpain 1 1417229_at chr19 A|19 3.0 cM 12333 15.5 3 1698 Foxn1 forkhead box N1 1456815_at chr11 B5|11 45.0 cM 15218 15.5 3 1699 Ogn osteoglycin 1419662_at chr13 A5 18295 15.5 3 1700 Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 1451716_at chr2 H2|2 91.0 cM 16658 15.5 3 1701 Kcne4 potassium voltage-gated channel, Isk-related subfamily, gene 4 1418156_at chr1 C4 57814 15.5 3 1702 Nfix nuclear factor I/X 1436363_a_at chr8 C1-C2|8 38.6 cM 18032 15.5 3 1703 Yes1 Yamaguchi sarcoma viral (v-yes) oncogene homolog 1 1418470_at chr5 B1|5 18.2 cM 22612 15.5 3 1704 Dgat2 diacylglycerol O-acyltransferase 2 1422678_at chr7 F1 67800 15.5 3 1705 AI662270 expressed sequence AI662270 1434068_s_at chr11 C 100043636 15.5 3 1706 Hopx HOP homeobox 1428662_a_at chr5 C3.3 74318 15.5 3 1707 Mboat1 membrane bound O-acyltransferase domain containing 1 1435323_a_at chr13 A3.2 218121 15.5 3 1708 Egfl8 EGF-like domain 8 1447953_at chr17 B1|17 18.8 cM 81701 15.5 3 1709 Islr immunoglobulin superfamily containing leucine-rich repeat 1418450_at chr9 B 26968 15.5 3 1710

PAGE 17

Glt25d2 glycosyltransferase 25 domain containing 2 1437930_at chr1 G3 269132 15.5 3 1711 Eps8 epidermal growth factor receptor pathway substrate 8 1422824_s_at chr6 G1|6 66.0 cM 13860 15.5 3 1712 Cd44 CD44 antigen 1452483_a_at chr2 E2|2 56.0 cM 12505 15.5 3 1713 1190003J15Rik RIKEN cDNA 1190003J15 gene 1431786_s_at chr7 F5 76974 15.5 3 1714 Ctss cathepsin S 1448591_at chr3 F2.1|3 42.7 cM 13040 15.5 3 1715 Mfsd6 major facilitator superfamily domain containing 6 1424463_at chr1 C1.1 98682 15.5 3 1716 Vgll3 vestigial like 3 (Drosophila) 1455299_at chr16 C1.3 73569 15.5 3 1717 Igfbp3 insulin-like growth factor binding protein 3 1458268_s_at chr11 A1|11 1.35 cM 16009 15.5 3 1718 Epas1 endothelial PAS domain protein 1 1435436_at chr17 E4 13819 15.5 3 1719 Rnasel ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) 1426604_at chr1 G2 24014 15.5 3 1720 Dcn decorin 1449368_at chr10 C3|10 55.0 cM 13179 15.5 3 1721 LOC100045163 /// Plbd1 similar to RIKEN cDNA 1100001H23 gene /// phospholipase B domain containing 1 1448786_at chr6 G1 100045163 /// 66857 15.5 3 1722 Vgll3 vestigial like 3 (Drosophila) 1453593_at chr16 C1.3 73569 15.5 3 1723 Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 1421752_a_at chr1 E2.1 20724 15.5 3 1724 Ldb2 LIM domain binding 2 1439557_s_at chr5 B3 16826 15.5 3 1725 Adamts5 /// LOC100048332 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) 1422561_at chr16 C3.3|16 62.0 cM 100048332 /// 23794 15.5 3 1726 Scel sciellin 1422837_at chr14 E 64929 15.5 3 1727 Endod1 endonuclease domain containing 1 1426540_at chr9 A3 71946 15.5 3 1728 LOC675405 /// Nalcn similar to voltage gated channel like 1 /// sodium leak channel, non-selective 1448083_at chr14 E5 338370 /// 675405 15.5 3 1729 Lrrc33 leucine rich repeat containing 33 1451174_at chr16 B2 224109 15.5 3 1730 Bicc1 bicaudal C homolog 1 (Drosophila) 1436029_at chr10 B5.3|10 38.6 cM 83675 15.5 3 1731 Agtr2 angiotensin II receptor, type 2 1415832_at chrX A2|X 12.5 cM 11609 15.5 3 1732 Aff1 AF4/FMR2 family, member 1 1418135_at chr5 E|5 56.0 cM 17355 15.5 3 1733 Myl7 myosin, light polypeptide 7, regulatory 1449071_at chr11 A1|11 0.75 cM 17898 15.5 3 1734 Mapre3 microtubule-associated protein, RP/EB family, member 3 1427079_at chr5 B1 100732 15.5 3 1735 Nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1428479_at chr18 E4|18 54.0 cM 18018 15.5 3 1736 Vgll3 vestigial like 3 (Drosophila) 1430596_s_at chr16 C1.3 73569 15.5 3 1737 Lrrc15 leucine rich repeat containing 15 1436055_at chr16 B2 74488 15.5 3 1738 Igfbp3 insulin-like growth factor binding protein 3 1423062_at chr11 A1|11 1.35 cM 16009 15.5 3 1739 Bgn biglycan 1448323_a_at chrX B|X 29.3 cM 12111 15.5 3 1740 Lox lysyl oxidase 1416121_at chr18 D1|18 29.0 cM 16948 15.5 3 1741 Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 1418601_at chr19 B|19 20.0 cM 26358 15.5 3 1742 Col5a1 collagen, type V, alpha 1 1416741_at chr2 A2-B|2 18.0 cM 12831 15.5 3 1743 Aplf aprataxin and PNKP like factor 1430297_a_at chr6 D1 72103 15.5 3 1744 Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 1416473_a_at chr9 C 56741 15.5 3 1745 Hnmt histamine N-methyltransferase 1417702_a_at chr2 A3 140483 15.5 3 1746 0710007G10Rik /// Tmem175 RIKEN cDNA 0710007G10 gene /// transmembrane protein 175 1435109_at chr5 F 68409 /// 72392 15.5 3 1747 ----1447996_at ----15.5 3 1748 Tsc22d2 TSC22 domain family, member 2 1453012_at chr3 D 72033 15.5 3 1749 Aqp1 aquaporin 1 1416203_at chr6 B3|6 27.0 cM 11826 15.5 3 1750 Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 1422671_s_at chr9 A3|9 3.0 cM 72560 15.5 3 1751 Klk11 kallikrein related-peptidase 11 1419201_at chr7 B4 56538 15.5 3 1752 Zbtb16 zinc finger and BTB domain containing 16 1439163_at chr9 A5.3|9 23.0 cM 235320 15.5 3 1753 Cd109 CD109 antigen 1425658_at chr9 E1 235505 15.5 3 1754 Ugt1a1 /// Ugt1a10 /// Ugt1a2 /// Ugt1a5 /// Ugt1a6a /// Ugt1a6b /// Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A1 1426260_a_at chr1 D /// chr1 D|1 51.7 cM 22236 /// 394430 /// 394432 /// 394433 /// 394434 /// 394435 /// 394436 // 15.5 3 1755 Pip5k1b phosphatidylinositol-4-phosphate 5-kinase, type 1 beta 1450389_s_at chr19 C1 18719 15.5 3 1756 Rgs5 regulator of G-protein signaling 5 1420940_x_at chr1 H2|1 86.5 cM 19737 15.5 3 1757 Krt79 keratin 79 1427352_at chr15 F3 223917 15.5 3 1758 Col14a1 collagen, type XIV, alpha 1 1428455_at chr15 D 12818 15.5 3 1759 Thbd thrombomodulin 1448529_at chr2 G3|2 84.0 cM 21824 15.5 3 1760 Nrp1 neuropilin 1 1448944_at chr8 E|8 73.0 cM 18186 15.5 3 1761 ----1455147_at ----15.5 3 1762 Thbs3 thrombospondin 3 1416623_at chr3 E3-F1|3 44.1 cM 21827 15.5 3 1763 AW551984 expressed sequence AW551984 1433434_at chr9 A5.1 244810 15.5 3 1764 Apba2 amyloid beta (A4) precursor protein-binding, family A, member 2 1427288_at chr7 C|7 25.5 cM 11784 15.5 3 1765 Thbs2 thrombospondin 2 1447862_x_at chr17 8.1 cM 21826 15.5 3 1766 Fcgrt Fc receptor, IgG, alpha chain transporter 1416978_at chr7 B4|7 23.0 cM 14132 15.5 3 1767 Rab27b RAB27b, member RAS oncogene family 1417215_at chr18 E2|18 45.0 cM 80718 15.5 3 1768 Cebpb CCAAT/enhancer binding protein (C/EBP), beta 1418901_at chr2 H3|2 95.5 cM 12608 15.5 3 1769 6430514M23Rik RIKEN cDNA 6430514M23 gene 1436492_x_at --399595 15.5 3 1770 Hspa1a heat shock protein 1A 1452388_at chr17 B1 193740 15.5 3 1771 Inhbb /// LOC100046802 inhibin beta-B /// similar to Inhbb protein 1426858_at chr1 E2.3|1 64.1 cM 100046802 /// 16324 15.5 3 1772 Dpyd dihydropyrimidine dehydrogenase 1427946_s_at chr3 G1 99586 15.5 3 1773 Aasdh aminoadipate-semialdehyde dehydrogenase 1440364_a_at chr5 C3.3 231326 15.5 3 1774 2310007B03Rik RIKEN cDNA 2310007B03 gene 1453511_at chr1 D 71874 15.5 3 1775 Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 1416474_at chr9 C 56741 15.5 3 1776 Arrdc2 arrestin domain containing 2 1428352_at chr8 C1 70807 15.5 3 1777 Cd44 CD44 antigen 1434376_at chr2 E2|2 56.0 cM 12505 15.5 3 1778 Zeb2 zinc finger E-box binding homeobox 2 1456389_at chr2 C1 24136 15.5 3 1779 Zfpm2 zinc finger protein, multitype 2 1449314_at chr15 C|15 19.3 cM 22762 15.5 3 1780 Rgs5 regulator of G-protein signaling 5 1417466_at chr1 H2|1 86.5 cM 19737 15.5 3 1781 Apba1 amyloid beta (A4) precursor protein binding, family A, member 1 1455369_at chr19 B 319924 15.5 3 1782 Postn periostin, osteoblast specific factor 1423606_at chr3 C 50706 15.5 3 1783 Dock10 dedicator of cytokinesis 10 1435343_at chr1 C4 210293 15.5 3 1784 Tmem158 transmembrane protein 158 1428074_at chr9 F4 72309 15.5 3 1785 Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 1439015_at chr19 D2-D3|19 29.0 cM 14585 15.5 3 1786 Ehbp1l1 EH domain binding protein 1-like 1 1416804_at chr19 A 114601 15.5 3 1787 Ogn osteoglycin 1419663_at chr13 A5 18295 15.5 3 1788 LOC100047360 /// Scml2 similar to sex comb on midleg-like 2 (Drosophila) /// sex comb on midleg-like 2 (Drosophila) 1456984_at chrX F4 100047360 /// 107815 15.5 3 1789 Kctd12 potassium channel tetramerisation domain containing 12 1434881_s_at chr14 E2.3 239217 15.5 3 1790 Plagl1 pleiomorphic adenoma gene-like 1 1450533_a_at chr10 A2|10 15.0 cM 22634 15.5 3 1791 Cadm2 cell adhesion molecule 2 1435147_x_at chr16 C1.3-C2 239857 15.5 3 1792 ----1446181_at ----15.5 3 1793 Srgn serglycin 1417426_at chr10 B4 19073 15.5 3 1794 Nfic nuclear factor I/C 1427665_a_at chr10 C1|10 43.0 cM 18029 15.5 3 1795 Ccrl1 chemokine (C-C motif) receptor-like 1 1426139_a_at chr9 F1 252837 15.5 3 1796 Upk3b uroplakin 3B 1434237_at chr5 G2 100647 15.5 3 1797 Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 1428776_at chr5 E5 75750 15.5 3 1798 Daam1 dishevelled associated activator of morphogenesis 1 1458662_at chr12 C3 208846 15.5 3 1799 Htr3b 5-hydroxytryptamine (serotonin) receptor 3B 1421652_at chr9 B 57014 15.5 3 1800 Rab40b Rab40b, member RAS oncogene family 1425756_at chr11 E2 217371 15.5 3 1801 Akap12 A kinase (PRKA) anchor protein (gravin) 12 1419706_a_at chr10 A1 83397 15.5 3 1802 Cdh8 cadherin 8 1422052_at chr8 D1|8 46.5 cM 12564 15.5 3 1803 Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1455660_at chr15 E1|15 43.3 cM 12983 15.5 3 1804 Nrp1 neuropilin 1 1418084_at chr8 E|8 73.0 cM 18186 15.5 3 1805 Depdc6 DEP domain containing 6 1451348_at chr15 D1|15 6.7 cM 97998 15.5 3 1806 Cadm3 cell adhesion molecule 3 1418921_at chr1 H3 94332 15.5 3 1807 Arhgap20 Rho GTPase activating protein 20 1427522_at chr9 A5.3 244867 15.5 3 1808 Pcdh12 protocadherin 12 1437928_at chr18 B3 53601 15.5 3 1809 Clec4a3 C-type lectin domain family 4, member a3 1429954_at chr6 F2 73149 15.5 3 1810 ----1439011_at ----15.5 3 1811 Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 1448789_at chr7 C 56847 15.5 3 1812 Mmrn2 multimerin 2 1439518_at chr14 B 105450 15.5 3 1813 Agtpbp1 ATP/GTP binding protein 1 1418332_a_at chr13 B2 67269 15.5 3 1814 Gbp6 guanylate binding protein 6 1425156_at chr3 H1 229900 15.5 3 1815 Gng4 guanine nucleotide binding protein (G protein), gamma 4 1447669_s_at chr13 A1|13 7.0 cM 14706 15.5 3 1816 Syt16 synaptotagmin XVI 1434429_at chr12 C3 238266 15.5 3 1817

PAGE 18

Cdh8 cadherin 8 1455365_at chr8 D1|8 46.5 cM 12564 15.5 3 1818 ----1444602_at ----15.5 3 1819 Casp12 caspase 12 1418981_at chr9 A1|9 1.11 cM 12364 15.5 3 1820 Tfpi tissue factor pathway inhibitor 1438530_at chr2 D 21788 15.5 3 1821 Tgm2 transglutaminase 2, C polypeptide 1433428_x_at chr2 H1|2 89.0 cM 21817 15.5 3 1822 ----1454105_at ----15.5 3 1823 5930430L01Rik RIKEN cDNA 5930430L01 gene 1445558_at --319982 15.5 3 1824 Ntn1 netrin 1 1454974_at chr11 B3 18208 15.5 3 1825 Ebf1 early B-cell factor 1 1416301_a_at chr11 B1.1|11 20.0 cM 13591 15.5 3 1826 Gast gastrin 1422915_at chr11 D|11 60.0 cM 14459 15.5 3 1827 Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 1427183_at chr11 A4 216616 15.5 3 1828 Vsig8 V-set and immunoglobulin domain containing 8 1436671_at chr1 H3 240916 15.5 3 1829 Pcdhb11 Protocadherin beta 11 1456710_at chr18 B3 93882 15.5 3 1830 Fgl2 fibrinogen-like protein 2 1421855_at chr5 A3|5 7.0 cM 14190 15.5 3 1831 Lrrfip1 leucine rich repeat (in FLII) interacting protein 1 1437477_at chr1 D 16978 15.5 3 1832 Rnf39 Ring finger protein 39 1441793_at chr17 B1 386454 15.5 3 1833 LOC100046963 /// Pgm5 similar to phosphoglucomutase 5 /// phosphoglucomutase 5 1437871_at chr19 B 100046963 /// 226041 15.5 3 1834 Nupr1 nuclear protein 1 1419665_a_at --56312 15.5 3 1835 H2-K1 histocompatibility 2, K1, K region 1427746_x_at chr17 B1|17 18.44 cM 14972 15.5 3 1836 1600029D21Rik RIKEN cDNA 1600029D21 gene 1423933_a_at chr9 B 76509 15.5 3 1837 Tspan8 tetraspanin 8 1424649_a_at chr10 D2 216350 15.5 3 1838 Lama4 laminin, alpha 4 1424807_at chr10 B1|10 25.0 cM 16775 15.5 3 1839 Klk5 kallikrein related-peptidase 5 1429230_at chr7 B4|7 24.0 cM 68668 15.5 3 1840 1110064A23Rik RIKEN cDNA 1110064A23 gene 1439543_at chr2 B 68893 15.5 3 1841 LOC100047138 /// Tesc similar to Tescalcin /// tescalcin 1418743_a_at chr5 F|5 64.0 cM 100047138 /// 57816 15.5 3 1842 Gpx3 glutathione peroxidase 3 1449106_at chr11 B3-B5 14778 15.5 3 1843 Serpinb8 serine (or cysteine) peptidase inhibitor, clade B, member 8 1422776_at chr1 D 20725 15.5 3 1844 Ankrd43 ankyrin repeat domain 43 1436998_at chr11 B1.3 237761 15.5 3 1845 Tbxa2r thromboxane A2 receptor 1419222_at chr10 C1|10 43.0 cM 21390 15.5 3 1846 Hfe hemochromatosis 1422645_at chr13 A2-A4|13 15.0 cM 15216 15.5 3 1847 Lum lumican 1423607_at chr10 C3|10 61.0 cM 17022 15.5 3 1848 LOC640441 /// Thbs1 similar to thrombospondin 1 /// thrombospondin 1 1421811_at chr2 F1-F3|2 65.0 cM 21825 /// 640441 15.5 3 1849 Ttc22 tetratricopeptide repeat domain 22 1457149_at chr4 C7 230576 15.5 3 1850 Abca8a ATP-binding cassette, sub-family A (ABC1), member 8a 1427371_at chr11 E1 217258 15.5 3 1851 Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 1425103_at chrX F5|X 70.5 cM 70008 15.5 3 1852 Abi3bp ABI gene family, member 3 (NESH) binding protein 1427054_s_at chr16 C1.1 320712 15.5 3 1853 Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 1417856_at chr7 A3|7 4.0 cM 19698 15.5 3 1854 2200001I15Rik RIKEN cDNA 2200001I15 gene 1437019_at chr14 B 69134 15.5 3 1855 Sgpp1 sphingosine-1-phosphate phosphatase 1 1420821_at chr12 C3 81535 15.5 3 1856 Optn optineurin 1435679_at chr2 A1|2 0.5 cM 71648 15.5 3 1857 Gcet2 germinal center expressed transcript 2 1420544_at chr16 B5 14525 15.5 3 1858 Thbs2 thrombospondin 2 1422571_at chr17 8.1 cM 21826 15.5 3 1859 Eps8l1 EPS8-like 1 1431821_a_at chr7 A1 67425 15.5 3 1860 Epb4.1l1 erythrocyte protein band 4.1-like 1 1421090_at chr2 H1|2 88.0 cM 13821 15.5 3 1861 Tmem117 transmembrane protein 117 1433615_at chr15 E3 320709 15.5 3 1862 Adra2a adrenergic receptor, alpha 2a 1433600_at chr19 D2|19 50.0 cM 11551 15.5 3 1863 9130230N09Rik RIKEN cDNA 9130230N09 gene 1437980_at --100137727 15.5 3 1864 Ms4a6d membrane-spanning 4-domains, subfamily A, member 6D 1419598_at chr19 A 68774 15.5 3 1865 Dock10 dedicator of cytokinesis 10 1439247_at chr1 C4 210293 15.5 3 1866 Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 1427019_at chr6 A3.1 19283 15.5 3 1867 Plxnc1 plexin C1 1450905_at chr10 C3 54712 15.5 3 1868 Parp12 poly (ADP-ribose) polymerase family, member 12 1426774_at chr6 B1 243771 15.5 3 1869 P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 1419853_a_at --18439 15.5 3 1870 Thbs2 thrombospondin 2 1450663_at chr17 8.1 cM 21826 15.5 3 1871 Tmem125 transmembrane protein 125 1434094_at chr4 D2.1 230678 15.5 3 1872 Ly6g6c lymphocyte antigen 6 complex, locus G6C 1449789_x_at chr17 B1 68468 15.5 3 1873 Gm106 predicted gene 106 1457429_s_at chr1 A3 226866 15.5 3 1874 Nxph1 neurexophilin 1 1459921_at chr6 A1 18231 15.5 3 1875 Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a 1416318_at chr13 A4|13 12.0 cM 66222 15.5 4 1876 Krt6b keratin 6B 1422588_at chr15 F2|15 58.76 cM 16688 15.5 4 1877 Lipk lipase, family member K 1443914_at chr19 C1 240633 15.5 4 1878 Kera keratocan 1418063_at chr10 C3|10 61.0 cM 16545 15.5 4 1879 Ly6g6c lymphocyte antigen 6 complex, locus G6C 1422749_at chr17 B1 68468 15.5 4 1880 Lor loricrin 1420183_at chr3 F1|3 42.1 cM 16939 15.5 4 1881 Lrrtm4 leucine rich repeat transmembrane neuronal 4 1437214_at chr6 C3 243499 15.5 4 1882 Gsta2 glutathione S-transferase, alpha 2 (Yc2) 1421040_a_at chr9 E1|9 44.0 cM 14858 15.5 4 1883 Sbsn suprabasin 1459897_a_at chr7A3|7 282619 15.5 4 1884 Tpsab1 tryptase alpha/beta 1 1426175_a_at chr17 A3.3|17 10.4 cM 17230 15.5 4 1885 Zcchc5 zinc finger, CCHC domain containing 5 1437355_at chrX D 213436 15.5 4 1886 Ivl involucrin 1439878_at chr3 F1|3 45.2 cM 16447 15.5 4 1887 Cnfn cornifelin 1429540_at chr7 A3 72383 15.5 4 1888 Smpx small muscle protein, X-linked 1418095_at chrX F4 66106 15.5 4 1889 Upk3b uroplakin 3B 1454881_s_at chr5 G2 100647 15.5 4 1890 Rarres1 retinoic acid receptor responder (tazarotene induced) 1 1438055_at chr3 E1 109222 15.5 4 1891 Il1rl1 interleukin 1 receptor-like 1 1425145_at chr1 B|1 20.0 cM 17082 15.5 4 1892 Serpinb12 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12 1429297_at chr1 D 71869 15.5 4 1893 Hal histidine ammonia lyase 1418645_at chr10 C2-D1|10 51.0 cM 15109 15.5 4 1894 Rdh12 retinol dehydrogenase 12 1431010_a_at chr12 D2 77974 15.5 4 1895 2310002J15Rik RIKEN cDNA 2310002J15 gene 1450532_at chr2 A3 67859 15.5 4 1896 Zbtb16 zinc finger and BTB domain containing 16 1419874_x_at chr9 A5.3|9 23.0 cM 235320 15.5 4 1897 Cma1 chymase 1, mast cell 1449456_a_at chr14 C3|14 20.0 cM 17228 15.5 4 1898 Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1435752_s_at chr6 G2|6 70.0 cM 20928 15.5 4 1899 Gsta1 /// Gsta2 glutathione S-transferase, alpha 1 (Ya) /// glutathione S-transferase, alpha 2 (Yc2) 1421041_s_at chr9 E1|9 43.0 cM /// chr9 E1|9 44.0 cM 14857 /// 14858 15.5 4 1900 Gsdma gasdermin A 1423634_at chr11 D 57911 15.5 4 1901 Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A 1437517_x_at chr1 E2.1 20248 15.5 4 1902 Abca9 ATP-binding cassette, sub-family A (ABC1), member 9 1440879_at chr11 E1 217262 15.5 4 1903 Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 1425102_a_at chrX F5|X 70.5 cM 70008 15.5 4 1904 Cpa3 carboxypeptidase A3, mast cell 1448730_at chr3 A2|3 13.2 cM 12873 15.5 4 1905 4833423E24Rik RIKEN cDNA 4833423E24 gene 1439528_at chr2 D 228151 15.5 4 1906 Ccl21a /// Ccl21b /// Ccl21c chemokine (C-C motif) ligand 21A 1419426_s_at chr4 A5|4 13.3 cM /// chr4 A5|4 13.34 cM 18829 /// 20298 /// 65956 15.5 4 1907 Sprr1a small proline-rich protein 1A 1449133_at chr3 F1|3 45.2 cM 20753 15.5 4 1908 Camk2d calcium/calmodulin-dependent protein kinase II, delta 1460630_at chr3 G1-G2 108058 15.5 4 1909 Adh6a alcohol dehydrogenase 6A (class V) 1429608_at chr3 G3 69117 15.5 4 1910 Krt13 keratin 13 1437344_x_at chr11 D|11 58.49 cM 16663 15.5 4 1911 Defb1 defensin beta 1 1419492_s_at chr8 A4|8 9.0 cM 13214 15.5 4 1912 Lipm lipase, family member M 1430551_s_at chr19 C1 78753 15.5 4 1913 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1439036_a_at chr1 H2.2|1 86.8 cM 11931 15.5 4 1914 Lypd5 Ly6/Plaur domain containing 5 1453809_at chr7 A3 76942 15.5 4 1915 Cadm3 cell adhesion molecule 3 1418922_at chr1 H3 94332 15.5 4 1916 Slc15a3 solute carrier family 15, member 3 1420697_at chr19 B 65221 15.5 4 1917 Krt4 keratin 4 1438394_x_at chr15 F3|15 58.84 cM 16682 15.5 4 1918 Them5 thioesterase superfamily member 5 1453801_at chr3 F2 66198 15.5 4 1919 Wnt16 wingless-related MMTV integration site 16 1422941_at chr6 A3 93735 15.5 4 1920 Orm1 orosomucoid 1 1451054_at chr4 B3|4 31.4 cM 18405 15.5 4 1921 Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 1421058_at chr3 G3|3 71.2 cM 11529 15.5 4 1922 ----1439789_at ----15.5 4 1923 Krt6a keratin 6A 1422784_at chr15 F2|15 58.77 cM 16687 15.5 4 1924

PAGE 19

Sbsn suprabasin 1439630_x_at chr7A3|7 282619 15.5 4 1925 Fibin fin bud initiation factor homolog (zebrafish) 1419376_at chr2 E3 67606 15.5 4 1926 Psapl1 prosaposin-like 1 1440186_s_at chr5 B3 76943 15.5 4 1927 Dpp4 dipeptidylpeptidase 4 1459973_x_at chr2 C2-D|2 35.0 cM 13482 15.5 4 1928 Defb1 defensin beta 1 1419491_at chr8 A4|8 9.0 cM 13214 15.5 4 1929 Egr1 early growth response 1 1417065_at chr18 C/D|18 16.0 cM 13653 15.5 4 1930 Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 1438856_x_at chr1 E2.1 20724 15.5 4 1931 3110027N22Rik RIKEN cDNA 3110027N22 gene 1430252_at --73168 15.5 4 1932 Adamts2 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 1435990_at chr11 B1.3 216725 15.5 4 1933 Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 1427082_at chr8 E1 74032 15.5 4 1934 B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 1455234_at chr2 C3 26877 15.5 4 1935 1500015O10Rik RIKEN cDNA 1500015O10 gene 1423261_at chr1 C1 78896 15.5 4 1936 Acsl1 acyl-CoA synthetase long-chain family member 1 1423883_at chr8 B2 14081 15.5 4 1937 Clip4 CAP-GLY domain containing linker protein family, member 4 1435504_at chr17 E2 78785 15.5 4 1938 Gria4 Glutamate receptor, ionotropic, AMPA4 (alpha 4) 1436772_at chr9 A1|9 8.0 cM 14802 15.5 4 1939 Mal myelin and lymphocyte protein, T-cell differentiation protein 1417275_at chr2 F1 17153 15.5 4 1940 Mal myelin and lymphocyte protein, T-cell differentiation protein 1432558_a_at chr2 F1 17153 15.5 4 1941 Gpr124 G protein-coupled receptor 124 1418379_s_at chr8 A3 78560 15.5 4 1942 Mcpt2 mast cell protease 2 1449989_at chr14 C3|14 20.0 cM 17225 15.5 4 1943 Rgs5 regulator of G-protein signaling 5 1420941_at chr1 H2|1 86.5 cM 19737 15.5 4 1944 Nov nephroblastoma overexpressed gene 1426852_x_at chr15 D1|15 22.5 cM 18133 15.5 4 1945 Filip1 filamin A interacting protein 1 1436650_at chr9 E2 70598 15.5 4 1946 Bhlhe22 basic helix-loop-helix family, member e22 1418271_at --59058 15.5 4 1947 Trf transferrin 1425546_a_at chr9 F1-F3|9 56.0 cM 22041 15.5 4 1948 Stfa3 stefin A3 1419709_at chr16 B3|16 22.85 cM 20863 15.5 4 1949 Camk1d calcium/calmodulin-dependent protein kinase ID 1452050_at chr2 A1 227541 15.5 4 1950 Slc26a7 Solute carrier family 26, member 7 1436279_at chr4 A1 208890 15.5 4 1951 Bgn biglycan 1437889_x_at chrX B|X 29.3 cM 12111 15.5 4 1952 Bpil2 bactericidal/permeability-increasing protein-like 2 1437232_at chr10 C1 270757 15.5 4 1953 Hdc histidine decarboxylase 1454713_s_at chr2 E5-G 15186 15.5 4 1954 Krt84 keratin 84 1451551_at chr15 F2|15 58.74 cM 16680 15.5 4 1955 Krt6a keratin 6A 1422783_a_at chr15 F2|15 58.77 cM 16687 15.5 4 1956 Serpinb3b /// Serpinb3c serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B 1422940_x_at chr1 E1-E2 /// chr1 E2.1 381286 /// 383548 15.5 4 1957 Adamtsl1 ADAMTS-like 1 1442063_at chr4 C4 77739 15.5 4 1958 Thsd1 thrombospondin, type I, domain 1 1449621_s_at chr8 A3 56229 15.5 4 1959 Ifi27l1 interferon, alpha-inducible protein 27 like 1 1454757_s_at chr12 E|12 51.0 cM 52668 15.5 4 1960 Gas7 growth arrest specific 7 1457270_at chr11 B3 14457 15.5 4 1961 Meox2 mesenchyme homeobox 2 1424233_at chr12 A3|12 20.0 cM 17286 15.5 4 1962 Sdr16c6 short chain dehydrogenase/reductase family 16C, member 6 1457025_at chr4 A1 242286 15.5 4 1963 Tshz2 teashirt zinc finger family member 2 1459250_at chr2 H3|2 99.0 cM 228911 15.5 4 1964 AA986860 expressed sequence AA986860 1433610_at chr1 E4 212439 15.5 4 1965 BC100530 /// Stfa1 cDNA sequence BC100530 /// stefin A1 1435761_at chr16 B3 /// chr16 B3|16 22.85 cM 100034684 /// 20861 15.5 4 1966 Serpinb11 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11 1449451_at chr1 E2.1 66957 15.5 4 1967 Nlrp10 NLR family, pyrin domain containing 10 1456211_at chr7 E3 244202 15.5 4 1968 Msln mesothelin 1460238_at chr17 A3.3 56047 15.5 4 1969 Slco3a1 solute carrier organic anion transporter family, member 3a1 1418030_at chr7 D1 108116 15.5 4 1970 Larp6 La ribonucleoprotein domain family, member 6 1418400_at chr9 B 67557 15.5 4 1971 Pof1b premature ovarian failure 1B 1427492_at chrX E1 69693 15.5 4 1972 Dleu2 deleted in lymphocytic leukemia, 2 1427410_at chr14 C3 668253 15.5 4 1973 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1423890_x_at chr1 H2.2|1 86.8 cM 11931 15.5 4 1974 Cytip cytohesin 1 interacting protein 1451206_s_at chr2 C1.1 227929 15.5 4 1975 Asprv1 aspartic peptidase, retroviral-like 1 1452732_at chr6 D1 67855 15.5 4 1976 Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1418453_a_at chr1 H2.2|1 86.8 cM 11931 15.5 4 1977 Casp12 caspase 12 1449297_at chr9 A1|9 1.11 cM 12364 15.5 4 1978 Slc26a7 solute carrier family 26, member 7 1425841_at chr4 A1 208890 15.5 4 1979 Sfmbt2 Scm-like with four mbt domains 2 1434353_at chr2 A1 353282 15.5 4 1980 Tmem45a transmembrane protein 45a 1422587_at chr16 C1.1 56277 15.5 4 1981 Csta cystatin A 1435760_at chr16 B3 209294 15.5 4 1982 Mpeg1 macrophage expressed gene 1 1427076_at chr19 A 17476 15.5 4 1983 Cytip cytohesin 1 interacting protein 1435697_a_at chr2 C1.1 227929 15.5 4 1984 Krt4 keratin 4 1418735_at chr15 F3|15 58.84 cM 16682 15.5 4 1985 Pkp3 plakophilin 3 1418832_at chr7 F5 56460 15.5 4 1986 Rims2 regulating synaptic membrane exocytosis 2 1422809_at chr15 C|15 16.0 cM 116838 15.5 4 1987 Pdzd2 PDZ domain containing 2 1435553_at chr15 A2 68070 15.5 4 1988 Acer1 alkaline ceramidase 1 1450825_at chr17 D 171168 15.5 4 1989 Elovl4 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 1424306_at chr9 E2 83603 15.5 4 1990 Muc15 mucin 15 1426941_at chr2 E3 269328 15.5 4 1991 Nov nephroblastoma overexpressed gene 1426851_a_at chr15 D1|15 22.5 cM 18133 15.5 4 1992 Psapl1 prosaposin-like 1 1429457_at chr5 B3 76943 15.5 4 1993 AI662270 expressed sequence AI662270 1434067_at chr11 C 100043636 15.5 4 1994 Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 1435239_at chr11 B1.3|11 31.0 cM 14799 15.5 4 1995 Elovl4 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 1451308_at chr9 E2 83603 15.5 4 1996 Apod apolipoprotein D 1416371_at chr16 B2|16 21.2 cM 11815 15.5 5 1997 Lor loricrin 1448745_s_at chr3 F1|3 42.1 cM 16939 15.5 5 1998 Rspo1 R-spondin homolog (Xenopus laevis) 1449319_at chr4 D2.2 192199 15.5 5 1999 Dpp4 dipeptidylpeptidase 4 1416697_at chr2 C2-D|2 35.0 cM 13482 15.5 5 2000 Dkkl1 dickkopf-like 1 1417787_at chr7 B4|7 23.0 cM 50722 15.5 5 2001 Alox12b /// LOC100045755 arachidonate 12-lipoxygenase, 12R type /// similar to arachidonate 12-lipoxygenase 1418266_at chr11 B3|11 37.0 cM 100045755 /// 11686 15.5 5 2002 Ly6d lymphocyte antigen 6 complex, locus D 1416930_at chr15 D3|15 43.3 cM 17068 15.5 5 2003 Krt6a keratin 6A 1427700_x_at chr15 F2|15 58.77 cM 16687 15.5 5 2004 Aox4 aldehyde oxidase 4 1419215_at chr1 23.2 cM 71872 15.5 5 2005 Krt13 keratin 13 1422454_at chr11 D|11 58.49 cM 16663 15.5 5 2006 2310011E23Rik RIKEN cDNA 2310011E23 gene 1435111_at --69610 15.5 5 2007 Dpt dermatopontin 1418511_at chr1 H2 56429 15.5 5 2008 Lipm lipase, family member M 1430550_at chr19 C1 78753 15.5 5 2009 Serpinb3b /// Serpinb3c serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B 1422939_at chr1 E1-E2 /// chr1 E2.1 381286 /// 383548 15.5 5 2010 Sprr1b small proline-rich protein 1B 1422672_at chr3 F1|3 45.2 cM 20754 15.5 5 2011 Krt77 keratin 77 1433923_at chr15 F3 406220 15.5 5 2012 Prr9 proline rich 9 1444061_at chr3 F1 109314 15.5 5 2013 Acer1 alkaline ceramidase 1 1439183_at chr17 D 171168 15.5 5 2014 1110020A10Rik RIKEN cDNA 1110020A10 gene 1456203_at --68648 15.5 5 2015 Sbsn suprabasin 1459898_at chr7A3|7 282619 15.5 5 2016 Hrnr hornerin 1451613_at --68723 15.5 5 2017 Psmb5 proteasome (prosome, macropain) subunit, beta type 5 1415676_a_at chr14 C2-D1|14 20.0 cM 19173 13.5 6 2018 2810002N01Rik RIKEN cDNA 2810002N01 gene 1429248_at chr12 F2 68020 13.5 6 2019 Ccdc58 coiled-coil domain containing 58 1424465_at chr16 B3 381045 13.5 6 2020 Wdyhv1 WDYHV motif containing 1 1434144_s_at chr15 D2|15 76773 13.5 6 2021 1110054O05Rik RIKEN cDNA 1110054O05 gene 1429087_at chr4 B3 66209 13.5 6 2022 Sec22a SEC22 vesicle trafficking protein homologe A (S. cerevisiae) 1416320_at chr16 B3 317717 13.5 6 2023 Txn2 thioredoxin 2 1452782_a_at chr15 E1 56551 13.5 6 2024 Rer1 RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae) 1460706_s_at chr4 E2 67830 13.5 6 2025 Zfp568 zinc finger protein 568 1435091_at chr7 B1 243905 13.5 6 2026 Ccnjl cyclin J-like 1436789_at chr11 B1.1 380694 13.5 6 2027 Tia1 cytotoxic granule-associated RNA binding protein 1 1416813_at chr6 D2 21841 13.5 6 2028 Pts 6-pyruvoyl-tetrahydropterin synthase 1450660_at chr9 A5.3 19286 13.5 6 2029 Cct4 chaperonin containing Tcp1, subunit 4 (delta) 1456082_x_at chr11 A3.2|11 13.0 cM 12464 13.5 6 2030 Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B 1450914_at chr19 A 18938 13.5 6 2031

PAGE 20

Btf3l4 basic transcription factor 3-like 4 1451223_a_at chr4 C7 70533 13.5 6 2032 Orc2l origin recognition complex, subunit 2-like (S. cerevisiae) 1418226_at chr1 C1.3 18393 13.5 6 2033 Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1422459_a_at chr7 F5 23997 13.5 6 2034 Shq1 SHQ1 homolog (S. cerevisiae) 1428927_at chr6 D3 72171 13.5 6 2035 Ranbp1 RAN binding protein 1 1422547_at chr16 A3|16 10.9 cM 19385 13.5 6 2036 2010320M18Rik RIKEN cDNA 2010320M18 gene 1434792_at --72093 13.5 6 2037 Ube2b ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae) 1423107_at chr11 B1.3 22210 13.5 6 2038 D8Ertd738e DNA segment, Chr 8, ERATO Doi 738, expressed 1449724_s_at chr8 C3|8 39.0 cM 101966 13.5 6 2039 Pomgnt1 protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase 1426618_a_at chr4 C7 68273 13.5 6 2040 Rpl7l1 ribosomal protein L7-like 1 1452049_at chr17 C 66229 13.5 6 2041 Igfbp2 insulin-like growth factor binding protein 2 1454159_a_at chr1 C3|1 36.1 cM 16008 13.5 6 2042 Pfdn5 prefoldin 5 1415736_at chr15 F3|15 61.7 cM 56612 13.5 6 2043 Cuedc2 CUE domain containing 2 1431145_a_at chr19 D1 67116 13.5 6 2044 Mrpl21 mitochondrial ribosomal protein L21 1452580_a_at chr19 A 353242 13.5 6 2045 Sfxn1 sideroflexin 1 1417559_at chr13 B1|13 35.0 cM 14057 13.5 6 2046 Rfxank regulatory factor X-associated ankyrin-containing protein 1419310_s_at chr8 C1 19727 13.5 6 2047 Rbm3 RNA binding motif protein 3 1422660_at chrX A1.1|X 2.0 cM 19652 13.5 6 2048 Cox6b2 cytochrome c oxidase subunit VIb polypeptide 2 1435275_at chr7 A1 333182 13.5 6 2049 Tatdn2 TatD DNase domain containing 2 1454769_at chr6 E3|6 49.6 cM 381801 13.5 6 2050 Ndufab1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 1428159_s_at chr7 F3 70316 13.5 6 2051 Foxk2 forkhead box K2 1428353_at chr11 E2 68837 13.5 6 2052 Htra2 HtrA serine peptidase 2 1460495_s_at chr6 C3|6 34.75 cM 64704 13.5 6 2053 Polr2f polymerase (RNA) II (DNA directed) polypeptide F 1415754_at chr15 E1|15 46.6 cM 69833 13.5 6 2054 Arl6 ADP-ribosylation factor-like 6 1417331_a_at chr16 C1.2 56297 13.5 6 2055 Mat2a methionine adenosyltransferase II, alpha 1433576_at chr6 C1 232087 13.5 6 2056 Rpl6 ribosomal protein L6 1416546_a_at chr5 F 19988 13.5 6 2057 Commd4 COMM domain containing 4 1417006_at chr9 C 66199 13.5 6 2058 ----1434568_at ----13.5 6 2059 Ftl1 /// Ftl2 /// Gm10116 ferritin light chain 1 /// ferritin light chain 2 /// ferritin light chain 1 pseudogene 1422302_s_at chr13 C1|13 /// chr4 D2.2 /// chr7 B4 14325 /// 14337 /// 634386 13.5 6 2060 Pds5a PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) 1425082_s_at chr5 C3.3 71521 13.5 6 2061 Banf1 barrier to autointegration factor 1 1421082_s_at chr19 A 23825 13.5 6 2062 Rilpl1 Rab interacting lysosomal protein-like 1 1447852_x_at chr5 F 75695 13.5 6 2063 Psma2 proteasome (prosome, macropain) subunit, alpha type 2 1448206_at chr13 A1 19166 13.5 6 2064 Med29 mediator complex subunit 29 1421903_at chr7 A3 67224 13.5 6 2065 Eif5a eukaryotic translation initiation factor 5A 1451470_s_at chr11 B3 276770 13.5 6 2066 Cog8 component of oligomeric golgi complex 8 1423617_at chr8 D3 97484 13.5 6 2067 Fastkd5 FAST kinase domains 5 1435369_at chr2 F1 380601 13.5 6 2068 LOC675851 /// Ndufc2 similar to NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2 1455036_s_at chr7 E3 675851 /// 68197 13.5 6 2069 Mrpl43 mitochondrial ribosomal protein L43 1415681_at chr19 D1 94067 13.5 6 2070 Arpc5l actin related protein 2/3 complex, subunit 5-like 1452044_at chr2 B 74192 13.5 6 2071 Thoc3 THO complex 3 1423971_at chr13 B2 73666 13.5 6 2072 Cul5 cullin 5 1456102_a_at chr9 C 75717 13.5 6 2073 Eif1b eukaryotic translation initiation factor 1B 1428272_at chr9 F4 68969 13.5 6 2074 Wdr61 WD repeat domain 61 1448102_a_at chr9 C 66317 13.5 6 2075 Klhdc2 kelch domain containing 2 1435086_s_at chr12 C3|12 30.0 cM 69554 13.5 6 2076 Sfrs3 splicing factor, arginine/serine-rich 3 (SRp20) 1416152_a_at chr17 A3.3|17 11.0 cM 20383 13.5 6 2077 Ccdc124 coiled-coil domain containing 124 1428605_at chr8 C1 234388 13.5 6 2078 Pih1d1 PIH1 domain containing 1 1447750_x_at chr7 B4 68845 13.5 6 2079 Dynll1 dynein light chain LC8-type 1 1448682_at chr5 F 56455 13.5 6 2080 Clp1 CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) 1423612_at chr2 D 98985 13.5 6 2081 Rfc4 replication factor C (activator 1) 4 1424321_at chr16 B1 106344 13.5 6 2082 Polr1d polymerase (RNA) I polypeptide D 1447320_x_at chr5 G3 20018 13.5 6 2083 Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 1415811_at chr17 D-E1 18140 13.5 6 2084 Chka choline kinase alpha 1450264_a_at chr19 A|19 3.0 cM 12660 13.5 6 2085 Eif3e eukaryotic translation initiation factor 3, subunit E 1460432_a_at chr15 B3.2|15 17.1 cM 16341 13.5 6 2086 2700060E02Rik RIKEN cDNA 2700060E02 gene 1448238_at chr14 A3 68045 13.5 6 2087 Tm2d2 TM2 domain containing 2 1439234_a_at chr8 A3 69742 13.5 6 2088 4930455C21Rik RIKEN cDNA 4930455C21 gene 1420329_at chr16 B4 76916 13.5 6 2089 Zbed4 zinc finger, BED domain containing 4 1427090_at chr15 E3 223773 13.5 6 2090 LOC100047782 /// Zfp771 similar to crooked legs CG14938-PB /// zinc finger protein 771 1440817_x_at chr7 F3 100047782 /// 244216 13.5 6 2091 Skp1a S-phase kinase-associated protein 1A 1423148_at chr11 B1.3|11 31.0 cM 21402 13.5 6 2092 Rrm2 ribonucleotide reductase M2 1448226_at chr12 A1.3|12 7.0 cM 20135 13.5 6 2093 2310002J21Rik RIKEN cDNA 2310002J21 gene 1431340_a_at chr19 D2 66360 13.5 6 2094 Mdp1 magnesium-dependent phosphatase 1 1450067_a_at chr14 C3 67881 13.5 6 2095 Pabpn1 poly(A) binding protein, nuclear 1 1415728_at chr14 C3|14 19.5 cM 54196 13.5 6 2096 Tia1 cytotoxic granule-associated RNA binding protein 1 1416812_at chr6 D2 21841 13.5 6 2097 Cdc14b CDC14 cell division cycle 14 homolog B (S. cerevisiae) 1437070_at chr13 B3 218294 13.5 6 2098 Fbxw2 F-box and WD-40 domain protein 2 1451524_at chr2 B 30050 13.5 6 2099 C1qbp complement component 1, q subcomponent binding protein 1455821_x_at chr11 B4|11 37.0 cM 12261 13.5 6 2100 Ccnb1 cyclin B1 1419943_s_at chr13 D1 268697 13.5 6 2101 Mrpl49 mitochondrial ribosomal protein L49 1423218_a_at chr19 A|19 3.0 cM 18120 13.5 6 2102 Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 1448286_at chrX F3 15108 13.5 6 2103 Commd7 /// LOC674161 COMM domain containing 7 /// similar to COMM domain-containing protein 7 1426765_at chr2 H1 674161 /// 99311 13.5 6 2104 Tceb2 transcription elongation factor B (SIII), polypeptide 2 1428263_a_at chr17 A3.3 67673 13.5 6 2105 Med28 mediator of RNA polymerase II transcription, subunit 28 homolog (yeast) 1416508_at chr5 B3 66999 13.5 6 2106 Cycs /// Gm10053 cytochrome c, somatic /// predicted gene 10053 1422483_a_at chr19 B /// chr6 B2.3|6 23.0 cM 13063 /// 672195 13.5 6 2107 Pla2g12a phospholipase A2, group XIIA 1452026_a_at chr3 H1 66350 13.5 6 2108 Dad1 defender against cell death 1 1418528_a_at chr14 C2|14 24.0 cM 13135 13.5 6 2109 Gpn1 GPN-loop GTPase 1 1417390_at chr5 B1 74254 13.5 6 2110 Rad51 RAD51 homolog (S. cerevisiae) 1418281_at chr2 F1|2 66.8 cM 19361 13.5 6 2111 Homer3 homer homolog 3 (Drosophila) 1424859_at chr8 C1 26558 13.5 6 2112 Zik1 zinc finger protein interacting with K protein 1 1433946_at chr7 A1 22775 13.5 6 2113 Morf4l1 mortality factor 4 like 1 1455077_a_at chr9 D1 21761 13.5 6 2114 Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 1439269_x_at chr5 G1 17220 13.5 6 2115 Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 1415810_at chr17 D-E1 18140 13.5 6 2116 Plk4 polo-like kinase 4 (Drosophila) 1419838_s_at chr3 B 20873 13.5 6 2117 1110008F13Rik RIKEN cDNA 1110008F13 gene 1416699_at chr2 H2 67388 13.5 6 2118 Gm10094 /// Sap18 predicted gene 10094 /// Sin3-associated polypeptide 18 1419445_s_at chr14 C3|14 28.5 cM /// chr8 D1 100041953 /// 20220 13.5 6 2119 Atp5g1 /// Gm10039 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 1416020_a_at chr11 D 100041835 /// 11951 13.5 6 2120 Zdhhc24 zinc finger, DHHC domain containing 24 1428278_at chr19 A 70605 13.5 6 2121 Polr2e polymerase (RNA) II (DNA directed) polypeptide E 1417138_s_at chr10 C1 66420 13.5 6 2122 Usp1 ubiquitin specific peptidase 1 1423674_at chr4 C6 230484 13.5 6 2123 5730494M16Rik RIKEN cDNA 5730494M16 gene 1441960_x_at chr18 A2 66648 13.5 6 2124 Ndufb11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 1455911_x_at chrX A1.3 104130 13.5 6 2125 Tubb5 tubulin, beta 5 1416256_a_at chr17 B1 22154 13.5 6 2126 Pigm phosphatidylinositol glycan anchor biosynthesis, class M 1418964_at chr1 H3|1 94.0 cM 67556 13.5 6 2127 Rpusd4 RNA pseudouridylate synthase domain containing 4 1452710_at chr9 A5.3 71989 13.5 6 2128 Cdca5 cell division cycle associated 5 1416802_a_at chr19 A 67849 13.5 6 2129 Cox19 COX19 cytochrome c oxidase assembly homolog (S. cerevisiae) 1434923_at chr5 G2 68033 13.5 6 2130 Stk16 serine/threonine kinase 16 1426160_a_at chr1 C3 20872 13.5 6 2131 Ddt D-dopachrome tautomerase 1417103_at chr10 C1|10 40.7 cM 13202 13.5 6 2132 Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) 1448319_at chr6 B1|6 13.0 cM 11677 13.5 6 2133 Nudt22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 1460358_s_at chr19 A 68323 13.5 6 2134 Fxyd6 FXYD domain-containing ion transport regulator 6 1417343_at chr9 A5.2 59095 13.5 6 2135 Ccna2 cyclin A2 1417911_at chr3 B|3 19.2 cM 12428 13.5 6 2136 Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 1440681_at chr7 C|7 30.0 cM 11441 13.5 6 2137 Plxnb1 plexin B1 1435254_at chr9 F2 235611 13.5 6 2138

PAGE 21

Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 1438320_s_at chr5 G1 17220 13.5 6 2139 D10Ertd322e DNA segment, Chr 10, ERATO Doi 322, expressed 1418439_at chr10 C2|10 39.0 cM 67270 13.5 6 2140 Scand3 SCAN domain containing 3 1429671_at chr5 G1.3 71970 13.5 6 2141 Fen1 flap structure specific endonuclease 1 1421731_a_at chr19 A 14156 13.5 6 2142 N6amt2 N-6 adenine-specific DNA methyltransferase 2 (putative) 1435270_x_at chr14 C3 68043 13.5 6 2143 Rrp1b ribosomal RNA processing 1 homolog B (S. cerevisiae) 1452118_at chr17 B1 72462 13.5 6 2144 Brwd1 bromodomain and WD repeat domain containing 1 1433955_at chr16 C4 93871 13.5 6 2145 Tomm40l translocase of outer mitochondrial membrane 40 homolog-like (yeast) 1455614_at chr1 H3 641376 13.5 6 2146 Arl5b ADP-ribosylation factor-like 5B 1437884_at chr2 A2 75869 13.5 6 2147 Casp6 caspase 6 1415995_at chr3 H1 12368 13.5 6 2148 2310009A05Rik RIKEN cDNA 2310009A05 gene 1435237_at --66364 13.5 6 2149 1110038D17Rik RIKEN cDNA 1110038D17 gene 1428071_at chr10 C1 68778 13.5 6 2150 Gabarapl2 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 1423187_at chr8 E1 93739 13.5 6 2151 Tnks tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1432630_at chr8 A4|8 18.0 cM 21951 13.5 6 2152 Chtf8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 1424028_at chr8 D3 214987 13.5 6 2153 Nhp2 NHP2 ribonucleoprotein homolog (yeast) 1416605_at chr11 B1.3|11 28.5 cM 52530 13.5 6 2154 Ikbkg inhibitor of kappaB kinase gamma 1421209_s_at chrX A7.3 16151 13.5 6 2155 Eif4e2 eukaryotic translation initiation factor 4E member 2 1435803_a_at chr1 D 26987 13.5 6 2156 Ubr7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1454616_at chr12 F1 66622 13.5 6 2157 Tm2d3 TM2 domain containing 3 1423951_at chr7 C 68634 13.5 6 2158 Cbx1 chromobox homolog 1 (Drosophila HP1 beta) 1436266_x_at chr11 D|11 58.0 cM 12412 13.5 6 2159 Zfp560 zinc finger protein 560 1438026_at chr9 A3 434377 13.5 6 2160 Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 1416030_a_at chr5 G1 17220 13.5 6 2161 Mea1 male enhanced antigen 1 1437943_s_at chr17 C|17 24.3 cM 17256 13.5 6 2162 Nudt19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 1432332_a_at chr7 B2|7 15.0 cM 110959 13.5 6 2163 Ppp2r2d protein phosphatase 2, regulatory subunit B, delta isoform 1424527_at chr7 F4|7 68.0 cM 52432 13.5 6 2164 Ccdc53 coiled-coil domain containing 53 1452721_a_at chr10 C2 67282 13.5 6 2165 8430406I07Rik RIKEN cDNA 8430406I07 gene 1429619_a_at chr2 H1 74528 13.5 6 2166 Stx18 syntaxin 18 1429288_x_at chr5 B3 71116 13.5 6 2167 Prpf4b PRP4 pre-mRNA processing factor 4 homolog B (yeast) 1455696_a_at chr13 A5 19134 13.5 6 2168 Mllt11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 1416313_at chr3 F2.1 56772 13.5 6 2169 Ndufb6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 1434057_at chr4 A5 230075 13.5 6 2170 Tfb1m transcription factor B1, mitochondrial 1435924_at chr17 A1 224481 13.5 6 2171 Sox12 SRY-box containing gene 12 1455562_at chr2 G3 20667 13.5 6 2172 Lsm6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1437108_at chr8 C1 78651 13.5 6 2173 Coil coilin 1416692_at chr11 D|11 50.0 cM 12812 13.5 6 2174 Wdr34 WD repeat domain 34 1429174_at chr2 B 71820 13.5 6 2175 Ube2a ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae) 1448772_at chrX A3.3 22209 13.5 6 2176 N6amt2 N-6 adenine-specific DNA methyltransferase 2 (putative) 1418386_at chr14 C3 68043 13.5 6 2177 Stard3nl STARD3 N-terminal like 1430274_a_at chr13 A3.1 76205 13.5 6 2178 Snrpd3 small nuclear ribonucleoprotein D3 1422884_at chr10 C1 67332 13.5 6 2179 C330018D20Rik RIKEN cDNA C330018D20 gene 1439783_at chr18 D3 77422 13.5 6 2180 Gm4204 /// Nap1l1 predicted gene 4204 /// nucleosome assembly protein 1-like 1 1420476_a_at chr1 E4|1 /// chr10 D1|10 60.0 cM 100043064 /// 53605 13.5 6 2181 Mettl1 methyltransferase like 1 1439155_at chr10 D3 17299 13.5 6 2182 Wiz widely-interspaced zinc finger motifs 1418202_a_at chr17 B2 22404 13.5 6 2183 Ube2n ubiquitin-conjugating enzyme E2N 1422559_at chr10 C2 93765 13.5 6 2184 Eif3k eukaryotic translation initiation factor 3, subunit K 1452674_a_at chr7 A3-B1 73830 13.5 6 2185 Cth cystathionase (cystathionine gamma-lyase) 1426243_at chr3 H4 107869 13.5 6 2186 Bap1 Brca1 associated protein 1 1426354_at chr14 B 104416 13.5 6 2187 Tmem120a transmembrane protein 120A 1435031_at chr5 G2 215210 13.5 6 2188 Gtlf3a gene trap locus F3a 1419203_at chr11 B2 24082 13.5 6 2189 Pxmp3 peroxisomal membrane protein 3 1420711_a_at chr3 A1|3 1.0 cM 19302 13.5 6 2190 Rpa1 replication protein A1 1437309_a_at chr11 B5|11 44.0 cM 68275 13.5 6 2191 Zfp184 zinc finger protein 184 (Kruppel-like) 1441997_at chr13 A3.1 193452 13.5 6 2192 1500032L24Rik RIKEN cDNA 1500032L24 gene 1452584_at chr15 E2 69029 13.5 6 2193 Cyc1 cytochrome c-1 1416604_at chr15 D3 66445 13.5 6 2194 Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 1422665_a_at chr10 A1|10 7.0 cM 18537 13.5 6 2195 Wdr8 WD repeat domain 8 1423923_a_at chr4 E2 59002 13.5 6 2196 Nol12 nucleolar protein 12 1423453_at chr15 E1 97961 13.5 6 2197 Jmjd6 jumonji domain containing 6 1420056_s_at chr11 E2|11 75.0 cM 107817 13.5 6 2198 Serf1 small EDRK-rich factor 1 1449509_at chr13 D1|13 53.0 cM 20365 13.5 6 2199 Ptges3 prostaglandin E synthase 3 (cytosolic) 1460221_at chr10 D3 56351 13.5 6 2200 Eri2 exoribonuclease 2 1438172_x_at chr7 F3|7 71151 13.5 6 2201 Tmem126a transmembrane protein 126A 1451000_at chr7 E1 66271 13.5 6 2202 Flrt3 fibronectin leucine rich transmembrane protein 3 1453102_at chr2 F3 71436 13.5 6 2203 Prim1 DNA primase, p49 subunit 1418369_at chr10 D3|10 77.0 cM 19075 13.5 6 2204 2900010J23Rik RIKEN cDNA 2900010J23 gene 1433480_at chr2 B 72931 13.5 6 2205 Senp3 SUMO/sentrin specific peptidase 3 1448866_at chr11 B4 80886 13.5 6 2206 Gm12657 /// Gm6421 /// H3f3a /// H3f3c /// LOC100045490 predicted gene 12657 /// similar to H3 histone, family 3A 1423262_a_at chr1 D2.3 /// chr13 D2.3 /// chr2 E5 /// chr4 C5 100045490 /// 15078 /// 623365 /// 625328 /// 667250 13.5 6 2207 Gm14176 /// Gm5931 /// LOC100044900 /// Ube2i predicted gene 14176 /// ubiquitin-conjugating enzyme E2I pseudogene 1422712_a_at chr17 A3.3 /// chr2 H1|2 /// chrX A1.1 100043681 /// 100044900 /// 22196 /// 546265 13.5 6 2208 Cox5b cytochrome c oxidase, subunit Vb 1416902_a_at chr1 B 12859 13.5 6 2209 Tmem183a transmembrane protein 183A 1417199_at chr1 E4 57439 13.5 6 2210 4632434I11Rik RIKEN cDNA 4632434I11 gene 1434240_at chr7 E2 74041 13.5 6 2211 Gm13072 /// Gm7828 /// Trmt112 predicted gene 13072 /// predicted gene 7828 /// tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1425299_s_at chr19 E1 /// chr4 E2 /// chr5 E2 627985 /// 665860 /// 67674 13.5 6 2212 Rbm4 RNA binding motif protein 4 1455517_at chr19 A 19653 13.5 6 2213 Cby1 chibby homolog 1 (Drosophila) 1451305_at chr15 E2|15 73739 13.5 6 2214 Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 1448178_a_at chr3 F|3 42.9 cM 12462 13.5 6 2215 Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) 1415945_at chr8 C1 17218 13.5 6 2216 5730528L13Rik RIKEN cDNA 5730528L13 gene 1430701_a_at chr4 B2 66665 13.5 6 2217 0610012G03Rik RIKEN cDNA 0610012G03 gene 1417003_at chr16 B2 106264 13.5 6 2218 Mrps24 mitochondrial ribosomal protein S24 1450865_s_at chr11 A1 64660 13.5 6 2219 Sssca1 Sjogren's syndrome/scleroderma autoantigen 1 homolog (human) 1417726_at chr19 A 56390 13.5 6 2220 Gm3244 /// Ndufb4 predicted gene 3244 /// NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4 1428076_s_at chr15 D3|15 /// chr16 B3 100041273 /// 68194 13.5 6 2221 Hoxa9 homeo box A9 1421579_at chr6 B3|6 26.32 cM 15405 13.5 6 2222 Luc7l Luc7 homolog (S. cerevisiae)-like 1428255_at chr17 B1|17 11.8 cM 66978 13.5 6 2223 Gm10709 /// Gm13841 /// Gm3550 /// Gm6344 /// Rpl29 predicted gene 10709 /// ribosomal protein L29 1436046_x_at chr13 B1|13 /// chr18 B1|18 /// chr5 F /// chr9 A1 /// chr9 100039782 /// 100041859 /// 19944 /// 622707 /// 665032 13.5 6 2224 Mdfi MyoD family inhibitor 1420713_a_at chr17 C|17 24.0 cM 17240 13.5 6 2225 Cdc2a cell division cycle 2 homolog A (S. pombe) 1448314_at chr10 B5.3|10 38.0 cM 12534 13.5 6 2226 Nubp2 nucleotide binding protein 2 1416512_at chr17 A3.3|17 10.0 cM 26426 13.5 6 2227 Cox5a cytochrome c oxidase, subunit Va 1448153_at chr9 B 12858 13.5 6 2228 Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 1423517_at chr5 G1.3 12466 13.5 6 2229 Galk1 galactokinase 1 1417177_at chr11 E2|11 78.0 cM 14635 13.5 6 2230 Polr2j polymerase (RNA) II (DNA directed) polypeptide J 1417720_at chr5 G1 20022 13.5 6 2231 Zswim7 zinc finger, SWIM-type containing 7 1428515_at chr11 B2 69747 13.5 6 2232 Prelid2 PRELI domain containing 2 1436194_at chr18 B3 77619 13.5 6 2233 Cox4i2 cytochrome c oxidase subunit IV isoform 2 1421373_at chr2 H2 84682 13.5 6 2234 Pgk1 phosphoglycerate kinase 1 1438640_x_at chrX C-D|X 45.0 cM 18655 13.5 6 2235 Wdr18 WD repeat domain 18 1454695_at chr10 C1 216156 13.5 6 2236 Tsen15 tRNA splicing endonuclease 15 homolog (S. cerevisiae) 1449933_a_at chr1 G3 66637 13.5 6 2237 Uqcc ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast) 1416436_a_at --56046 13.5 6 2238 Fam118b family with sequence similarity 118, member B 1454236_a_at chr9 A5.3 109229 13.5 6 2239 Cnih cornichon homolog (Drosophila) 1423727_at chr14 C1 12793 13.5 6 2240 Tead2 TEA domain family member 2 1448519_at chr7 B5|7 23.0 cM 21677 13.5 6 2241 2610018G03Rik RIKEN cDNA 2610018G03 gene 1419032_at chrX A3.3 70415 13.5 6 2242 Dgcr6 DiGeorge syndrome critical region gene 6 1428753_a_at chr16 B2|16 10.71 cM 13353 13.5 6 2243 Snrpa1 small nuclear ribonucleoprotein polypeptide A' 1417352_s_at chr7 C 68981 13.5 6 2244 Hes6 hairy and enhancer of split 6 (Drosophila) 1436050_x_at chr1 D 55927 13.5 6 2245

PAGE 22

BC024063 /// Gm4924 cDNA sequence BC024063 /// predicted gene 4924 1456853_at chr10 C1 237412 /// 666584 13.5 6 2246 Ccng2 cyclin G2 1416488_at chr5 E3.3-F1.3 12452 13.5 6 2247 Gtf3c6 general transcription factor IIIC, polypeptide 6, alpha 1420626_at chr10 B1 67371 13.5 6 2248 BC005561 HO complex 2 pseudogene 1427461_at chr5 E5 100042165 13.5 6 2249 Slc7a6os solute carrier family 7, member 6 opposite strand 1429596_at chr8 D3 66432 13.5 6 2250 Skp2 S-phase kinase-associated protein 2 (p45) 1436000_a_at chr15 A2 27401 13.5 6 2251 Fzd3 frizzled homolog 3 (Drosophila) 1421157_at chr14 D1|14 27.0 cM 14365 13.5 6 2252 Prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 1426483_at chr7 F1 72981 13.5 6 2253 Rfc5 replication factor C (activator 1) 5 1452917_at chr5 F 72151 13.5 6 2254 Rpl21 ribosomal protein L21 1455767_x_at chr5 G3 19933 13.5 6 2255 Skp2 S-phase kinase-associated protein 2 (p45) 1460247_a_at chr15 A2 27401 13.5 6 2256 B230118H07Rik RIKEN cDNA B230118H07 gene 1416824_at chr2 E2|2 56.0 cM 68170 13.5 6 2257 Fam64a family with sequence similarity 64, member A 1452073_at chr11 B4 109212 13.5 6 2258 Grhl2 grainyhead-like 2 (Drosophila) 1427046_at chr15 C 252973 13.5 6 2259 Cdca4 cell division cycle associated 4 1423683_at chr12 F2 71963 13.5 6 2260 Bivm basic, immunoglobulin-like variable motif containing 1434288_at chr1 C1.1 246229 13.5 6 2261 Mrps23 mitochondrial ribosomal protein S23 1421875_a_at chr11 C|11 48.0 cM 64656 13.5 6 2262 Eif3e eukaryotic translation initiation factor 3, subunit E 1439268_x_at chr15 B3.2|15 17.1 cM 16341 13.5 6 2263 Cux1 cut-like homeobox 1 1425611_a_at chr5 G2|5 78.0 cM 13047 13.5 6 2264 Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1451884_a_at chr17 B1|17 18.95 cM 27756 13.5 6 2265 Cycs cytochrome c, somatic 1422484_at chr6 B2.3|6 23.0 cM 13063 13.5 6 2266 Tmem110 transmembrane protein 110 1438693_at chr14 B 69179 13.5 6 2267 Emd emerin 1417357_at chrX A7.3|X 29.81 cM 13726 13.5 6 2268 Atg5 autophagy-related 5 (yeast) 1418236_s_at chr10 B2|10 26.0 cM 11793 13.5 6 2269 Orc2l origin recognition complex, subunit 2-like (S. cerevisiae) 1418227_at chr1 C1.3 18393 13.5 6 2270 2310061C15Rik RIKEN cDNA 2310061C15 gene 1427921_s_at chr8 E1 66531 13.5 6 2271 Stx18 syntaxin 18 1453819_x_at chr5 B3 71116 13.5 6 2272 Birc5 baculoviral IAP repeat-containing 5 1424278_a_at chr11 E2 11799 13.5 6 2273 Psmg1 proteasome (prosome, macropain) assembly chaperone 1 1448307_at chr16 C4 56088 13.5 6 2274 Mrpl2 mitochondrial ribosomal protein L2 1448811_at chr17 C 27398 13.5 6 2275 Cyb5b cytochrome b5 type B 1448844_at chr8 D2 66427 13.5 6 2276 Bud31 BUD31 homolog (yeast) 1433611_s_at chr5 G2 231889 13.5 6 2277 Psma6 proteasome (prosome, macropain) subunit, alpha type 6 1437144_x_at chr12 C1 26443 13.5 6 2278 Zfp622 zinc finger protein 622 1447775_x_at chr15 B1|15 8.9 cM 52521 13.5 6 2279 Lyrm4 LYR motif containing 4 1455588_at chr13 A3.3 380840 13.5 6 2280 Pebp1 phosphatidylethanolamine binding protein 1 1415950_a_at chr5 F|5 63.0 cM 23980 13.5 6 2281 Ndufs6 NADH dehydrogenase (ubiquinone) Fe-S protein 6 1433603_at --407785 13.5 6 2282 Gm10075 /// Gm3879 /// Gm5853 /// Gm5937 /// Gm7468 /// Hmg1l1 /// Hmgb1 /// predicted gene 10075 1439463_x_at chr1 A3|1 /// chr3 F2.2 /// chr5 G3|5 83.0 cM /// chr6 G3 / 100040413 /// 100042515 /// 100045972 /// 100046019 /// 15289 /// 434174 / 13.5 6 2283 Mrps35 mitochondrial ribosomal protein S35 1452111_at chr6 G3 232536 13.5 6 2284 Khdrbs3 KH domain containing, RNA binding, signal transduction associated 3 1453317_a_at chr15 D3|15 37.5 cM 13992 13.5 6 2285 Rps27l ribosomal protein S27-like 1435429_x_at chr9 D 67941 13.5 6 2286 Timm17b translocase of inner mitochondrial membrane 17b 1460685_at chrX A1.1|X 2.0 cM 21855 13.5 6 2287 Muted muted 1448979_at chr13 A3.3|13 21.0 cM 17828 13.5 6 2288 Zfp41 zinc finger protein 41 1454927_at chr15 D3 22701 13.5 6 2289 Bub3 budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) 1416815_s_at chr7 F3|7 61.0 cM 12237 13.5 6 2290 Baalc brain and acute leukemia, cytoplasmic 1426329_s_at chr15 C|15 16.0 cM 118452 13.5 6 2291 Tor1a torsin family 1, member A (torsin A) 1426515_a_at chr2 B 30931 13.5 6 2292 Gm10774 /// Polr2l /// Usp50 predicted gene 10774 /// polymerase (RNA) II (DNA directed) polypeptide L /// ubiquitin specific peptidase 50 1428296_at chr2 F1 /// chr2 F2 /// chr7 F5 100043714 /// 66491 /// 75083 13.5 6 2293 Tmem128 transmembrane protein 128 1448317_at chr5 B3 66309 13.5 6 2294 Tacc3 transforming, acidic coiled-coil containing protein 3 1417450_a_at chr5 B2 21335 13.5 6 2295 Tm2d2 TM2 domain containing 2 1456663_x_at chr8 A3 69742 13.5 6 2296 Snrpb small nuclear ribonucleoprotein B 1419260_a_at chr2 F1|2 73.0 cM 20638 13.5 6 2297 Isca2 iron-sulfur cluster assembly 2 homolog (S. cerevisiae) 1424154_a_at chr12 D3 74316 13.5 6 2298 Plk4 polo-like kinase 4 (Drosophila) 1426580_at chr3 B 20873 13.5 6 2299 Egfl7 EGF-like domain 7 1435823_x_at chr2 B 353156 13.5 6 2300 ----1435952_at ----13.5 6 2301 Apex1 apurinic/apyrimidinic endonuclease 1 1416135_at chr14 C3|14 18.5 cM 11792 13.5 6 2302 Casp3 caspase 3 1449839_at chr8 B1.1|8 26.0 cM 12367 13.5 6 2303 Eif3i eukaryotic translation initiation factor 3, subunit I 1416233_at chr4 D2.2|4 61.0 cM 54709 13.5 6 2304 Zdhhc16 zinc finger, DHHC domain containing 16 1421115_a_at chr19 D1 74168 13.5 6 2305 Timm22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1448517_at chr11 B4 56322 13.5 6 2306 Dynll2 dynein light chain LC8-type 2 1418371_at chr11 C 68097 13.5 6 2307 2610018G03Rik RIKEN cDNA 2610018G03 gene 1419033_at chrX A3.3 70415 13.5 6 2308 1110007L15Rik RIKEN cDNA 1110007L15 gene 1451700_a_at chr5 G2 67604 13.5 6 2309 Cab39l calcium binding protein 39-like 1449966_s_at chr14 C3-D1 69008 13.5 6 2310 B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 1420993_at chr16 B1 108105 13.5 6 2311 Gtf2h3 general transcription factor IIH, polypeptide 3 1454092_a_at chr5 F|5 68.0 cM 209357 13.5 6 2312 Snhg10 small nucleolar RNA host gene (non-protein coding) 10 1447993_a_at chr12 E 69434 13.5 6 2313 LOC100048338 /// Pdlim1 similar to Pdlim1 protein /// PDZ and LIM domain 1 (elfin) 1416554_at chr19 D1 100048338 /// 54132 13.5 6 2314 Eef1g /// LOC100047986 eukaryotic translation elongation factor 1 gamma /// similar to eukaryotic translation elongation factor 1 gamma 1417364_at chr19 A 100047986 /// 67160 13.5 6 2315 Chrac1 chromatin accessibility complex 1 1422505_at chr15 E1 93696 13.5 6 2316 Ube2s ubiquitin-conjugating enzyme E2S 1416726_s_at chr7 A1 77891 13.5 6 2317 Kcnmb4 /// LOC100047870 potassium large conductance calcium-activated channel, subfamily M, beta member 4 1449471_at chr10 D2 100047870 /// 58802 13.5 6 2318 Aurka aurora kinase A 1424511_at chr2 H3|2 100.0 cM 20878 13.5 6 2319 Arl1 ADP-ribosylation factor-like 1 1447090_s_at chr10 C1 104303 13.5 6 2320 Ndufab1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 1447919_x_at chr7 F3 70316 13.5 6 2321 Akr1a4 aldo-keto reductase family 1, member A4 (aldehyde reductase) 1430123_a_at chr4 C7 58810 13.5 6 2322 Cdk2ap1 /// LOC100047490 CDK2 (cyclin-dependent kinase 2)-associated protein 1 /// similar to putative oral cancer suppressor 1435509_x_at chr5 F 100047490 /// 13445 13.5 6 2323 1810013D10Rik RIKEN cDNA 1810013D10 gene 1454614_at chr5 C1 66278 13.5 6 2324 Ntf5 neurotrophin 5 1440353_at chr7 B4|7 23.0 cM 78405 13.5 6 2325 Sult5a1 sulfotransferase family 5A, member 1 1449816_at chr8 E1 57429 13.5 6 2326 Cldn12 claudin 12 1433781_a_at chr5 A1 64945 13.5 6 2327 D11Wsu99e DNA segment, Chr 11, Wayne State University 99, expressed 1449258_at chr11 E2|11 25.0 cM 28081 13.5 6 2328 Mettl2 methyltransferase like 2 1435713_at chr11 E1|11 63.0 cM 52686 13.5 6 2329 Pkn2 protein kinase N2 1437296_at chr3 H1 109333 13.5 6 2330 Ndufb11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 1416056_a_at chrX A1.3 104130 13.5 6 2331 Triap1 TP53 regulated inhibitor of apoptosis 1 1460702_at chr5 F 69076 13.5 6 2332 AW209491 expressed sequence AW209491 1423512_at chr13 A1 105351 13.5 6 2333 Gm71 predicted gene 71 1455726_at chr12 C2 207965 13.5 6 2334 Sugt1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1426425_at chr14 D3 67955 13.5 6 2335 Sfrs2 splicing factor, arginine/serine-rich 2 (SC-35) 1452439_s_at chr11 E2|11 73.0 cM 20382 13.5 6 2336 Pdap1 PDGFA associated protein 1 1434020_at chr5 G2 231887 13.5 6 2337 Mrpl3 mitochondrial ribosomal protein L3 1422464_at chr9 F1 94062 13.5 6 2338 Myg1 melanocyte proliferating gene 1 1424088_at chr15 F3 60315 13.5 6 2339 Mrpl49 mitochondrial ribosomal protein L49 1423219_a_at chr19 A|19 3.0 cM 18120 13.5 6 2340 Uqcrc2 ubiquinol cytochrome c reductase core protein 2 1435757_a_at chr7 F2 67003 13.5 6 2341 Ccdc59 coiled-coil domain containing 59 1449446_at chr10 D1|10 59.0 cM 52713 13.5 6 2342 Btf3 basic transcription factor 3 1449643_s_at chr13 D1 218490 13.5 6 2343 Nupl1 nucleoporin like 1 1429878_a_at chr14 D1 71844 13.5 6 2344 Uba2 ubiquitin-like modifier activating enzyme 2 1448283_a_at chr7 B1 50995 13.5 6 2345 LOC100044627 /// Rpl23 similar to HL23 ribosomal protein /// ribosomal protein L23 1460680_a_at chr11 D|11 58.0 cM 100044627 /// 65019 13.5 6 2346 Ldhb lactate dehydrogenase B 1416183_a_at chr6 G2|6 62.0 cM 16832 13.5 6 2347 Nedd8 neural precursor cell expressed, developmentally down-regulated gene 8 1423715_a_at chr14 C3|14 20.5 cM 18002 13.5 6 2348 Polr2g polymerase (RNA) II (DNA directed) polypeptide G 1416270_at chr19 A 67710 13.5 6 2349 Tm2d2 TM2 domain containing 2 1439235_x_at chr8 A3 69742 13.5 6 2350 Mrps22 mitochondrial ribosomal protein S22 1416595_at chr9 E4 64655 13.5 6 2351 Nipa2 non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) 1426717_at chr7 B5 93790 13.5 6 2352

PAGE 23

Cblb Casitas B-lineage lymphoma b 1437304_at chr16 B5 208650 13.5 6 2353 Dohh deoxyhypusine hydroxylase/monooxygenase 1417322_at chr10 C1 102115 13.5 6 2354 Bax BCL2-associated X protein 1416837_at chr7 B5|7 23.0 cM 12028 13.5 6 2355 Gemin6 gem (nuclear organelle) associated protein 6 1424300_at chr17 E3 67242 13.5 6 2356 Gm7901 /// Gm8096 /// Gm8341 /// Gm9252 /// Phgdh 3-phosphoglycerate dehydrogenase pseudogene 1426657_s_at chr15 A2|15 /// chr3 E1 /// chr7 B3 /// chr8 A2|8 /// chr8 236539 /// 666036 /// 666422 /// 666875 /// 668576 13.5 6 2357 Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1423831_at chr5 A3 108099 13.5 6 2358 Gm3932 predicted gene 3932 1439251_at chr5 F|5 100042616 13.5 6 2359 Cisd1 CDGSH iron sulfur domain 1 1416850_s_at chr10 B5.3|10 38.0 cM 52637 13.5 6 2360 1500001M20Rik RIKEN cDNA 1500001M20 gene 1428684_at chr6 E3 68971 13.5 6 2361 Hoxd13 homeo box D13 1440626_at chr2 C3|2 45.0 cM 15433 13.5 6 2362 Tm2d2 TM2 domain containing 2 1439454_x_at chr8 A3 69742 13.5 6 2363 Hmgn1 high mobility group nucleosomal binding domain 1 1422495_a_at chr16 C4|16 69.8 cM 15312 13.5 6 2364 Dhrs7b /// LOC100045214 dehydrogenase/reductase (SDR family) member 7B 1424869_at chr11 B2 100045214 /// 216820 13.5 6 2365 3110001D03Rik RIKEN cDNA 3110001D03 gene 1423317_at chr4 C3 66928 13.5 6 2366 Nudt8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 1450111_a_at chr19 A 66387 13.5 6 2367 Bola3 bolA-like 3 (E. coli) 1433970_at chr6 C3 78653 13.5 6 2368 Msx2 homeobox, msh-like 2 1449559_at chr13 B1|13 32.0 cM 17702 13.5 6 2369 Ndufa3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 1452790_x_at chr7 A1 66091 13.5 6 2370 Atg5 autophagy-related 5 (yeast) 1415684_at chr10 B2|10 26.0 cM 11793 13.5 6 2371 Mettl1 methyltransferase like 1 1419122_at chr10 D3 17299 13.5 6 2372 Taf9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1422778_at chr13 D1 108143 13.5 6 2373 Zwint ZW10 interactor 1429787_x_at chr10 B5.3|10 38.0 cM 52696 13.5 6 2374 Morf4l1 mortality factor 4 like 1 1456142_x_at chr9 D1 21761 13.5 6 2375 1110059E24Rik RIKEN cDNA 1110059E24 gene 1416841_at chr19 C1 66206 13.5 6 2376 C80913 expressed sequence C80913 1419274_at chr7 B2 19777 13.5 6 2377 Ngfrap1 nerve growth factor receptor (TNFRSF16) associated protein 1 1428842_a_at chrX F1|X 57.5 cM 12070 13.5 6 2378 Usp3 ubiquitin specific peptidase 3 1425022_at chr9 C 235441 13.5 6 2379 5730494M16Rik RIKEN cDNA 5730494M16 gene 1428189_at chr18 A2 66648 13.5 6 2380 Nipsnap1 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans) 1448465_at chr11 A1 18082 13.5 6 2381 Kif5c kinesin family member 5C 1422945_a_at chr2 32.5 cM 16574 13.5 6 2382 Yaf2 YY1 associated factor 2 1423399_a_at chr15 F1 67057 13.5 6 2383 Gfer growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration) 1426995_a_at chr17 A3.3|17 10.0 cM 11692 13.5 6 2384 Nap1l1 nucleosome assembly protein 1-like 1 1429227_x_at chr10 D1|10 60.0 cM 53605 13.5 6 2385 Lpin2 lipin 2 1452836_at chr17 E1.3 64898 13.5 6 2386 Arglu1 arginine and glutamate rich 1 1433597_at chr8 A1.1 234023 13.5 6 2387 Prpf3 PRP3 pre-mRNA processing factor 3 homolog (yeast) 1424314_at chr3 F2 70767 13.5 6 2388 Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1426385_x_at chr11 B2|11 44.17 cM 22627 13.5 6 2389 LOC100046421 /// Tmem222 similar to D4Ertd196e protein /// transmembrane protein 222 1452686_s_at chr4 D2.3|4 65.7 cM 100046421 /// 52174 13.5 6 2390 Haus1 HAUS augmin-like complex, subunit 1 1424955_at chr18 E3 225745 13.5 6 2391 Pycrl pyrroline-5-carboxylate reductase-like 1416400_at chr15 E1 66194 13.5 6 2392 Nap1l1 nucleosome assembly protein 1-like 1 1420479_a_at chr10 D1|10 60.0 cM 53605 13.5 6 2393 Timm17a translocase of inner mitochondrial membrane 17a 1426256_at chr1 F 21854 13.5 6 2394 Gfer growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration) 1452272_a_at chr17 A3.3|17 10.0 cM 11692 13.5 6 2395 Suv39h1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1427382_a_at chrX A1-A2|X 1.95 cM 20937 13.5 6 2396 Mrps17 mitochondrial ribosomal protein S17 1453728_a_at chr5 F 66258 13.5 6 2397 Dnlz DNL-type zinc finger 1428913_at chr2 A3|2 20.0 cM 52838 13.5 6 2398 Cdc42se2 CDC42 small effector 2 1435220_s_at chr11 B1.3 72729 13.5 6 2399 Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 1451968_at chr1 E|1 42.0 cM 22596 13.5 6 2400 Bzw1 basic leucine zipper and W2 domains 1 1450845_a_at chr1 C2 66882 13.5 6 2401 Surf6 surfeit gene 6 1416864_at chr2 A3|2 15.5 cM 20935 13.5 6 2402 Lrrc42 leucine rich repeat containing 42 1424049_at chr4 C7 77809 13.5 6 2403 Ssna1 Sjogren's syndrome nuclear autoantigen 1 1448643_at chr2 A3 68475 13.5 6 2404 1500011H22Rik RIKEN cDNA 1500011H22 gene 1424192_at chr5 F 68948 13.5 6 2405 Mtx2 metaxin 2 1430500_s_at chr2 D 53375 13.5 6 2406 Ryk receptor-like tyrosine kinase 1451789_a_at chr9 F1|9 61.0 cM 20187 13.5 6 2407 Tpd52l2 tumor protein D52-like 2 1417106_at chr2 H4 66314 13.5 6 2408 Fh1 fumarate hydratase 1 1424828_a_at chr1 H4 14194 13.5 6 2409 Gm10257 /// Gm6421 /// Gm6749 /// Gm7194 /// H3f3a /// H3f3c /// LOC100045490 predicted gene 10257 1423263_at chr1 D2.3 /// chr13 D1 /// chr13 D2.3 /// chr15 B3.1 /// ch 100045490 /// 15078 /// 544973 /// 623365 /// 625328 /// 627371 /// 636952 13.5 6 2410 Rnf114 ring finger protein 114 1427874_at --81018 13.5 6 2411 2700078E11Rik RIKEN cDNA 2700078E11 gene 1451556_a_at chr19 D3 78832 13.5 6 2412 Kifap3 kinesin-associated protein 3 1417181_a_at chr1 H1 16579 13.5 6 2413 Asf1a ASF1 anti-silencing function 1 homolog A (S. cerevisiae) 1423511_at chr10 B3 66403 13.5 6 2414 Ndufs7 NADH dehydrogenase (ubiquinone) Fe-S protein 7 1424313_a_at chr10 C1|10 43.0 cM 75406 13.5 6 2415 Glrx2 glutaredoxin 2 (thioltransferase) 1422998_a_at chr1 F|1 77.8 cM 69367 13.5 6 2416 Klhdc2 kelch domain containing 2 1460678_at chr12 C3|12 30.0 cM 69554 13.5 6 2417 Tbcb tubulin folding cofactor B 1448533_at chr7 B1 66411 13.5 6 2418 Creld2 cysteine-rich with EGF-like domains 2 1452754_at chr15 E3 76737 13.5 6 2419 Tssc4 tumor-suppressing subchromosomal transferable fragment 4 1427661_a_at chr7 F5|7 69.3 cM 56844 13.5 6 2420 Dnajc8 DnaJ (Hsp40) homolog, subfamily C, member 8 1452683_at chr4 D2.3 68598 13.5 6 2421 Mpnd MPN domain containing 1451357_at chr17 D 68047 13.5 6 2422 Brcc3 BRCA1/BRCA2-containing complex, subunit 3 1452128_a_at chrX A7.3 210766 13.5 6 2423 Orc5l origin recognition complex, subunit 5-like (S. cerevisiae) 1415830_at chr5 A3 26429 13.5 6 2424 Sept6 septin 6 1424181_at chrX A2 56526 13.5 6 2425 Gart phosphoribosylglycinamide formyltransferase 1416283_at chr16 C3-C4|16 63.0 cM 14450 13.5 6 2426 Racgap1 Rac GTPase-activating protein 1 1451358_a_at chr15 F1 26934 13.5 6 2427 Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1418874_a_at chr3 F2.1|3 50.0 cM 19185 13.5 6 2428 Gnb1 guanine nucleotide binding protein (G protein), beta 1 1417432_a_at chr4 E2|4 79.4 cM 14688 13.5 6 2429 Cbr1 carbonyl reductase 1 1460196_at chr16 C4|16 67.0 cM 12408 13.5 6 2430 BC003940 cDNA sequence BC003940 1460690_at chr11 E2 192173 13.5 6 2431 Kifc1 /// LOC100044746 kinesin family member C1 /// similar to Kifc1 protein 1449877_s_at chr17 A3.3 100044746 /// 16580 13.5 6 2432 Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 1415914_at chr11 B1.3 15384 13.5 6 2433 Eif4a3 eukaryotic translation initiation factor 4A, isoform 3 1417242_at chr11 E2 192170 13.5 6 2434 Ilf2 interleukin enhancer binding factor 2 1417949_at chr3 F2 67781 13.5 6 2435 Clns1a chloride channel, nucleotide-sensitive, 1A 1423181_s_at chr7 E3|7 50.0 cM 12729 13.5 6 2436 Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 1451175_at chr8 B1.3 76687 13.5 6 2437 Cetn2 centrin 2 1418579_at chrX B|X 28.85 cM 26370 13.5 6 2438 Ndufv2 NADH dehydrogenase (ubiquinone) flavoprotein 2 1428179_at chr17 E1.2 72900 13.5 6 2439 Glrx2 glutaredoxin 2 (thioltransferase) 1437679_a_at chr1 F|1 77.8 cM 69367 13.5 6 2440 Zcchc17 zinc finger, CCHC domain containing 17 1452084_at chr4 D2.2 619605 13.5 6 2441 Ndufb11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 1416057_at chrX A1.3 104130 13.5 6 2442 Ufc1 ubiquitin-fold modifier conjugating enzyme 1 1416327_at chr1 H3|1 93.0 cM 66155 13.5 6 2443 Ndufa8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 1423692_at chr2 B 68375 13.5 6 2444 Kif2c kinesin family member 2C 1437611_x_at chr4 D1 73804 13.5 6 2445 Ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 1416070_a_at chr1 E2 66942 13.5 6 2446 Tmem49 transmembrane protein 49 1423722_at chr11 C 75909 13.5 6 2447 Rpl7l1 ribosomal protein L7-like 1 1426386_at chr17 C 66229 13.5 6 2448 Ccdc43 coiled-coil domain containing 43 1418543_s_at chr11 E1|11 60.0 cM 52715 13.5 6 2449 Srp14 signal recognition particle 14 1418567_a_at chr2 E5 20813 13.5 6 2450 Ccdc43 coiled-coil domain containing 43 1449128_at chr11 E1|11 60.0 cM 52715 13.5 6 2451 Cpsf3l cleavage and polyadenylation specific factor 3-like 1423964_at chr4 E2|4 83.0 cM 71957 13.5 6 2452 Wdr5 WD repeat domain 5 1416581_at chr2 A3 140858 13.5 6 2453 Dgcr8 DiGeorge syndrome critical region gene 8 1435439_at chr16 B1|16 10.9 cM 94223 13.5 6 2454 Calm2 calmodulin 2 1423807_a_at chr17 E4 12314 13.5 6 2455 Churc1 churchill domain containing 1 1425455_a_at chr12 C3 211151 13.5 6 2456 Gtpbp5 GTP binding protein 5 1451467_s_at chr2 H4|2 105.0 cM 52856 13.5 6 2457 Bnip2 BCL2/adenovirus E1B interacting protein 2 1453993_a_at chr9 D 12175 13.5 6 2458 4930579G24Rik RIKEN cDNA 4930579G24 gene 1429364_at chr3 F1 75939 13.5 6 2459

PAGE 24

Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha 1452662_a_at chr12 D1 13665 13.5 6 2460 Psmb2 proteasome (prosome, macropain) subunit, beta type 2 1448262_at chr4 D2.2|4 57.6 cM 26445 13.5 6 2461 Cdc20 cell division cycle 20 homolog (S. cerevisiae) 1416664_at chr4 D2.1 107995 13.5 6 2462 Bag2 BCL2-associated athanogene 2 1423948_at chr1 B 213539 13.5 6 2463 LOC100048093 /// Rnf8 similar to Ring finger protein 8 /// ring finger protein 8 1424120_at chr17 A3.3 100048093 /// 58230 13.5 6 2464 Dem1 defects in morphology 1 homolog (S. cerevisiae) 1428903_at chr4 D2.2 73172 13.5 6 2465 Tmem132a transmembrane protein 132A 1416845_at chr19 A 98170 13.5 6 2466 Rnf138 ring finger protein 138 1454064_a_at chr18 A2 56515 13.5 6 2467 Senp2 SUMO/sentrin specific peptidase 2 1451717_s_at chr16 B1 75826 13.5 6 2468 Dynlrb1 dynein light chain roadblock-type 1 1428257_s_at chr2 H1 67068 13.5 6 2469 Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon 1433886_at chr16 A3 224045 13.5 6 2470 2310061F22Rik RIKEN cDNA 2310061F22 gene 1428350_at chr8 E1 66965 13.5 6 2471 Amd1 S-adenosylmethionine decarboxylase 1 1448484_at chr10 B2|10 25.0 cM 11702 13.5 6 2472 Lsm14b LSM14 homolog B (SCD6, S. cerevisiae) 1455155_at chr2 H4 241846 13.5 6 2473 Mbd3 methyl-CpG binding domain protein 3 1417728_at chr10 C1|10 43.0 cM 17192 13.5 6 2474 Cct4 chaperonin containing Tcp1, subunit 4 (delta) 1433447_x_at chr11 A3.2|11 13.0 cM 12464 13.5 6 2475 Cdca7 cell division cycle associated 7 1428069_at chr2 C3 66953 13.5 6 2476 Top2a topoisomerase (DNA) II alpha 1454694_a_at chr11 D|11 57.0 cM 21973 13.5 6 2477 Mrps30 mitochondrial ribosomal protein S30 1427158_at chr13 D2.3 59054 13.5 6 2478 Slc39a3 solute carrier family 39 (zinc transporter), member 3 1417881_at chr10 C1 106947 13.5 6 2479 Fusip1 FUS interacting protein (serine-arginine rich) 1 1418527_a_at chr4 D3 14105 13.5 6 2480 LOC100048559 /// Sfrs1 similar to splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) 1428099_a_at chr11 C|11 49.0 cM 100048559 /// 110809 13.5 6 2481 Tmem167 transmembrane protein 167 1450904_at chr13 C3 66074 13.5 6 2482 Wdr43 WD repeat domain 43 1428390_at chr17 E1.3 72515 13.5 6 2483 Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 1459987_s_at chr3 F|3 42.9 cM 12462 13.5 6 2484 Cdv3 carnitine deficiency-associated gene expressed in ventricle 3 1415704_a_at chr9 F1 321022 13.5 6 2485 Trappc2l trafficking protein particle complex 2-like 1417105_at chr8 E1 59005 13.5 6 2486 Tusc4 tumor suppressor candidate 4 1417046_at chr9 F1 56032 13.5 6 2487 Gm13819 /// Gm2423 /// Ywhaq predicted gene 13819 /// predicted gene 2423 1460590_s_at chr12 A1.3 /// chr13 A1 /// chr5 F 100039786 /// 22630 /// 664895 13.5 6 2488 Pold1 polymerase (DNA directed), delta 1, catalytic subunit 1448187_at chr7 B4|7 23.0 cM 18971 13.5 6 2489 Bap1 Brca1 associated protein 1 1452039_a_at chr14 B 104416 13.5 6 2490 Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 1451131_at chr7 F3 54208 13.5 6 2491 Tcea1 transcription elongation factor A (SII) 1 1419258_at chr1 A1 21399 13.5 6 2492 Phf5a PHD finger protein 5A 1424170_at chr15 E 68479 13.5 6 2493 Gm5806 /// Gm9855 /// Tdg predicted gene 5806 /// predicted gene 9855 /// thymine DNA glycosylase 1435715_x_at chr10 B2 /// chr10 C1|10 43.0 cM /// chr15 E1 21665 /// 545124 /// 624784 13.5 6 2494 Anapc5 anaphase-promoting complex subunit 5 1456695_x_at chr5 F 59008 13.5 6 2495 Tmx1 thioredoxin-related transmembrane protein 1 1451195_a_at chr12 C2 72736 13.5 6 2496 Lmnb1 lamin B1 1423520_at chr18 D3|18 29.0 cM 16906 13.5 6 2497 Prpf31 PRP31 pre-mRNA processing factor 31 homolog (yeast) 1448633_at chr7 A1 68988 13.5 6 2498 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 1437398_a_at chr1 H2 56752 13.5 6 2499 Mrpl16 mitochondrial ribosomal protein L16 1450880_at chr19 B 94063 13.5 6 2500 0610007P14Rik RIKEN cDNA 0610007P14 gene 1454161_s_at chr12 D2 58520 13.5 6 2501 Preb prolactin regulatory element binding 1416502_a_at chr5 B1 50907 13.5 6 2502 Gm2423 /// Ywhaq predicted gene 2423 /// tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 1432842_s_at chr12 A1.3 /// chr13 A1 100039786 /// 22630 13.5 6 2503 1600021P15Rik RIKEN cDNA 1600021P15 gene 1439014_at chr16 B2 239796 13.5 6 2504 Myef2 myelin basic protein expression factor 2, repressor 1425350_a_at chr2 F1|2 73.0 cM 17876 13.5 6 2505 Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase 1423565_at chr5 E1 67054 13.5 6 2506 D10Ertd641e DNA segment, Chr 10, ERATO Doi 641, expressed 1449338_at chr10 B4|10 30.0 cM 52717 13.5 6 2507 Fubp1 far upstream element (FUSE) binding protein 1 1433482_a_at chr3 H3|3 70.5 cM 51886 13.5 6 2508 Hn1l hematological and neurological expressed 1-like 1433696_at chr17 A3.3|17 11.0 cM 52009 13.5 6 2509 Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 1452046_a_at chr5 F-G1 19047 13.5 6 2510 Ubac2 ubiquitin associated domain containing 2 1423928_at chr14 E5 68889 13.5 6 2511 Cox10 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) 1435380_at chr11 B3 70383 13.5 6 2512 Unc119b unc-119 homolog B (C. elegans) 1460688_s_at chr5 F 106840 13.5 6 2513 Mrps25 mitochondrial ribosomal protein S25 1418716_at chr6 D3 64658 13.5 6 2514 Etf1 eukaryotic translation termination factor 1 1451208_at chr18 B1 225363 13.5 6 2515 Aagab alphaand gamma-adaptin binding protein 1424016_at chr9 D 66939 13.5 6 2516 5830415L20Rik RIKEN cDNA 5830415L20 gene 1426279_at chr5 A2|5 68152 13.5 6 2517 Ppib peptidylprolyl isomerase B 1450911_at chr9 C 19035 13.5 6 2518 Glmn glomulin, FKBP associated protein 1418839_at chr5 E5 170823 13.5 6 2519 8430410A17Rik RIKEN cDNA 8430410A17 gene 1423786_at chr6 D1 232210 13.5 6 2520 Ube2d3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 1423113_a_at chr3 G3 66105 13.5 6 2521 Zscan21 zinc finger and SCAN domain containing 21 1420095_s_at chr5 G2|5 78.0 cM 22697 13.5 6 2522 Ift52 intraflagellar transport 52 homolog (Chlamydomonas) 1434696_at chr2 H2 245866 13.5 6 2523 Pcnp PEST proteolytic signal containing nuclear protein 1428314_at chr16 C1.1 76302 13.5 6 2524 2410042D21Rik RIKEN cDNA 2410042D21 gene 1433872_at chr2 E4 72425 13.5 6 2525 Ankrd54 ankyrin repeat domain 54 1451182_s_at chr15 E1|15 46.6 cM 223690 13.5 6 2526 Egln2 EGL nine homolog 2 (C. elegans) 1416533_at chr7 A3|7 7.0 cM 112406 13.5 6 2527 Sumo3 SMT3 suppressor of mif two 3 homolog 3 (yeast) 1422457_s_at chr10 C1|10 41.6 cM 20610 13.5 6 2528 Psmd6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 1423697_at chr14 A1 66413 13.5 6 2529 Drg1 developmentally regulated GTP binding protein 1 1448336_at chr11 A1 13494 13.5 6 2530 Uqcrc2 ubiquinol cytochrome c reductase core protein 2 1428631_a_at chr7 F2 67003 13.5 6 2531 Ube2c ubiquitin-conjugating enzyme E2C 1452954_at chr2 H3|2 93.0 cM 68612 13.5 6 2532 Anapc5 anaphase-promoting complex subunit 5 1435178_x_at chr5 F 59008 13.5 6 2533 A130010J15Rik RIKEN cDNA A130010J15 gene 1429394_at chr1 H6 319266 13.5 6 2534 Med8 mediator of RNA polymerase II transcription, subunit 8 homolog (yeast) 1431423_a_at chr4 D1|4 80509 13.5 6 2535 Tmem39b transmembrane protein 39b 1437910_at chr4 D2.3 230770 13.5 6 2536 Patz1 POZ (BTB) and AT hook containing zinc finger 1 1429739_a_at chr11 A1 56218 13.5 6 2537 Cnot8 CCR4-NOT transcription complex, subunit 8 1451102_at chr11 B1.3 69125 13.5 6 2538 Prpf19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) 1449635_at chr19 A|19 6.0 cM 28000 13.5 6 2539 Eif5 eukaryotic translation initiation factor 5 1454664_a_at chr12 F1|12 57.0 cM 217869 13.5 6 2540 Npc2 Niemann Pick type C2 1416901_at chr12 D1 67963 13.5 6 2541 Gpr177 G protein-coupled receptor 177 1437434_a_at chr3 H4 68151 13.5 6 2542 Cacybp calcyclin binding protein 1452047_at chr1 H1 12301 13.5 6 2543 Aspscr1 alveolar soft part sarcoma chromosome region, candidate 1 (human) 1423912_at chr11 E2 68938 13.5 6 2544 Rap1b RAS related protein 1b 1435519_at chr10 D2 215449 13.5 6 2545 Pdap1 PDGFA associated protein 1 1434019_at chr5 G2 231887 13.5 6 2546 Rnps1 ribonucleic acid binding protein S1 1437851_x_at chr17 A3.3 19826 13.5 6 2547 Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 1435859_x_at chr5 A3|5 9.0 cM 19181 13.5 6 2548 Got2 glutamate oxaloacetate transaminase 2, mitochondrial 1417716_at chr8 D1|8 46.0 cM 14719 13.5 6 2549 H2afy H2A histone family, member Y 1424572_a_at chr13 B2 26914 13.5 6 2550 Gatad1 GATA zinc finger domain containing 1 1425599_a_at chr5 A2 67210 13.5 6 2551 Txnl4a thioredoxin-like 4A 1433698_a_at chr18 E3 27366 13.5 6 2552 Nme7 non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase) 1418217_at chr1 H2.2 171567 13.5 6 2553 Tcp1 t-complex protein 1 1448122_at chr17 A3-B|17 7.5 cM 21454 13.5 6 2554 Eif6 eukaryotic translation initiation factor 6 1427578_a_at chr2 H1 16418 13.5 6 2555 Glud1 glutamate dehydrogenase 1 1448253_at chr14 B|14 15.5 cM 14661 13.5 6 2556 Basp1 /// LOC100045716 brain abundant, membrane attached signal protein 1 /// similar to 22 kDa neuronal tissue-enriched acidic protein 1428572_at chr15 B1 100045716 /// 70350 13.5 6 2557 Dnajc4 DnaJ (Hsp40) homolog, subfamily C, member 4 1417934_at chr19 A 57431 13.5 6 2558 Grwd1 glutamate-rich WD repeat containing 1 1452171_at chr7 B4 101612 13.5 6 2559 Brms1l breast cancer metastasis-suppressor 1-like 1460443_at chr12 C1|12 23.0 cM 52592 13.5 6 2560 Ncbp2 nuclear cap binding protein subunit 2 1423045_at chr16 B2 68092 13.5 6 2561 Elp3 Elongation protein 3 homolog (S. cerevisiae) 1436762_x_at chr14 D1 74195 13.5 6 2562 Ddx50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1417875_at chr10 B4 94213 13.5 6 2563 Gnl3 guanine nucleotide binding protein-like 3 (nucleolar) 1433656_a_at chr14 B|14 11.0 cM 30877 13.5 6 2564 Eif2s2 eukaryotic translation initiation factor 2, subunit 2 (beta) 1448819_at chr2 H1|2 90.0 cM 67204 13.5 6 2565 Spg21 spastic paraplegia 21 homolog (human) 1451036_at chr9 C|9 40.0 cM 27965 13.5 6 2566

PAGE 25

Med22 mediator complex subunit 22 1421528_a_at chr2 A3|2 15.5 cM 20933 13.5 6 2567 Hmbs hydroxymethylbilane synthase 1426475_at chr9 A5.2|9 26.0 cM 15288 13.5 6 2568 Zfp821 zinc finger protein 821 1426889_at chr8 D3 75871 13.5 6 2569 Mtap methylthioadenosine phosphorylase 1451346_at chr4 C4 66902 13.5 6 2570 Zc3hc1 zinc finger, C3HC type 1 1426654_at chr6 A3.3 232679 13.5 6 2571 Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1450968_at chr13 A3.3 66694 13.5 6 2572 Klhl9 kelch-like 9 (Drosophila) 1433442_at chr4 C4 242521 13.5 6 2573 Ccnb2 cyclin B2 1450920_at chr9 D 12442 13.5 6 2574 Rab4b RAB4B, member RAS oncogene family 1451643_a_at chr7 A3|7 7.4 cM 19342 13.5 6 2575 Mrpl27 mitochondrial ribosomal protein L27 1415690_at chr11 D|11 56.0 cM 94064 13.5 6 2576 Fkbp4 FK506 binding protein 4 1416362_a_at chr6 F3 14228 13.5 6 2577 Dusp19 dual specificity phosphatase 19 1418038_s_at chr2 C3 68082 13.5 6 2578 Gstm5 glutathione S-transferase, mu 5 1416842_at chr3 F2.3 14866 13.5 6 2579 Dcps decapping enzyme, scavenger 1424080_at chr9 A4 69305 13.5 6 2580 Pqlc3 PQ loop repeat containing 1424906_at chr12 A1.1 217430 13.5 6 2581 Mrps11 mitochondrial ribosomal protein S11 1460195_at chr7 D3 67994 13.5 6 2582 Ahsa1 AHA1, activator of heat shock protein ATPase homolog 1 (yeast) 1424147_at chr12 D2 217737 13.5 6 2583 Jagn1 jagunal homolog 1 (Drosophila) 1417064_at chr6 E3 67767 13.5 6 2584 ----1442044_at ----13.5 6 2585 Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha 1420491_at chr12 D1 13665 13.5 6 2586 Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 1421148_a_at chr7 F4 21843 13.5 6 2587 Rbbp4 retinoblastoma binding protein 4 1454791_a_at --19646 13.5 6 2588 Wdr74 WD repeat domain 74 1416890_at chr19 A 107071 13.5 6 2589 ENSMUSG00000074747 predicted gene, ENSMUSG00000074747 1428126_a_at chr10 D2 382423 13.5 6 2590 E2f6 E2F transcription factor 6 1448835_at chr12 A1.1|12 6.0 cM 50496 13.5 6 2591 Mycbp c-myc binding protein 1427939_s_at chr4 D2.2 56309 13.5 6 2592 Arl3 ADP-ribosylation factor-like 3 1450706_a_at chr19 D1 56350 13.5 6 2593 Ard1a ARD1 homolog A, N-acetyltransferase (S. cerevisiae) 1417118_a_at chrX A7.3 56292 13.5 6 2594 Ppp2r2d protein phosphatase 2, regulatory subunit B, delta isoform 1420033_s_at chr7 F4|7 68.0 cM 52432 13.5 6 2595 Usf1 upstream transcription factor 1 1426164_a_at chr1 H|1 93.3 cM 22278 13.5 6 2596 2310016E02Rik RIKEN cDNA 2310016E02 gene 1435522_a_at chr5 B1 67695 13.5 6 2597 Cetn2 centrin 2 1438647_x_at chrX B|X 28.85 cM 26370 13.5 6 2598 Snip1 Smad nuclear interacting protein 1 1459773_x_at chr4 D2.2 76793 13.5 6 2599 1110004F10Rik RIKEN cDNA 1110004F10 gene 1423335_at chr7 F3 56372 13.5 6 2600 Drg1 developmentally regulated GTP binding protein 1 1434688_x_at chr11 A1 13494 13.5 6 2601 2900092E17Rik RIKEN cDNA 2900092E17 gene 1449618_s_at chr7 F4 67278 13.5 6 2602 Iah1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 1429119_at chr12 A1.3 67732 13.5 6 2603 Josd2 Josephin domain containing 2 1449046_a_at chr7 B2 66124 13.5 6 2604 Eif4g2 eukaryotic translation initiation factor 4, gamma 2 1452758_s_at chr7 F1|7 51.52 cM 13690 13.5 6 2605 Mpp6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 1449348_at chr6 B2.3 56524 13.5 6 2606 Map1lc3b microtubule-associated protein 1 light chain 3 beta 1415930_a_at chr8 E1 67443 13.5 6 2607 Dph3 DPH3 homolog (KTI11, S. cerevisiae) 1431200_a_at chr14 B 105638 13.5 6 2608 Eral1 Era (G-protein)-like 1 (E. coli) 1460548_a_at chr11 B5 57837 13.5 6 2609 Gm9811 /// Rpl14 ribosomal protein L14 pseudogene /// ribosomal protein L14 1426793_a_at chr7 B4|7 /// chr9 F4 100040970 /// 67115 13.5 6 2610 Ttc26 tetratricopeptide repeat domain 26 1435401_at chr6 B1 264134 13.5 6 2611 Ctps cytidine 5'-triphosphate synthase 1416563_at chr4 D2.2|4 57.0 cM 51797 13.5 6 2612 Vrk2 vaccinia related kinase 2 1453343_s_at chr11 A3.3 69922 13.5 6 2613 Ttc1 tetratricopeptide repeat domain 1 1448537_at chr11 B1.1 66827 13.5 6 2614 Tmem11 transmembrane protein 11 1454669_at chr11 B2 216821 13.5 6 2615 Mrpl36 mitochondrial ribosomal protein L36 1422819_at chr13 C1 94066 13.5 6 2616 Prpf38a PRP38 pre-mRNA processing factor 38 (yeast) domain containing A 1433565_at chr4 C7 230596 13.5 6 2617 Pigc phosphatidylinositol glycan anchor biosynthesis, class C 1424189_at chr1 H2.1 67292 13.5 6 2618 LOC100047782 /// Zfp771 similar to crooked legs CG14938-PB /// zinc finger protein 771 1440971_x_at chr7 F3 100047782 /// 244216 13.5 6 2619 Tbc1d7 TBC1 domain family, member 7 1428598_at chr13 A4 67046 13.5 6 2620 Hn1 hematological and neurological expressed sequence 1 1416028_a_at chr11 E2|11 70.0 cM 15374 13.5 6 2621 Taf9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1451509_at chr13 D1 108143 13.5 6 2622 Hspa8 heat shock protein 8 1420623_x_at chr9 A5.1|9 24.0 cM 15481 13.5 6 2623 Traf3ip2 TRAF3 interacting protein 2 1448508_at chr10 B1 103213 13.5 6 2624 2700097O09Rik RIKEN cDNA 2700097O09 gene 1428810_at chr12 C1 72658 13.5 6 2625 Cbx3 /// LOC633016 chromobox homolog 3 (Drosophila HP1 gamma) /// similar to chromobox homolog 3 1448504_a_at chr6 B-C|6 26.0 cM 12417 /// 633016 13.5 6 2626 Uchl3 /// Uchl4 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) /// ubiquitin carboxyl-terminal esterase L4 1449855_s_at chr14 E2.3|14 48.0 cM /// chr9 C|9 35.0 cM 50933 /// 93841 13.5 6 2627 Tob2 transducer of ERBB2, 2 1417309_at chr15 E2 57259 13.5 6 2628 B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2 1434135_at chr13 A1 97884 13.5 6 2629 Actg1 actin, gamma, cytoplasmic 1 1415779_s_at chr11 E2 11465 13.5 6 2630 Tsr2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 1426939_at chrX F3 69499 13.5 6 2631 Eif4e2 eukaryotic translation initiation factor 4E member 2 1421985_a_at chr1 D 26987 13.5 6 2632 Clpp caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) 1416616_s_at chr17 D|17 34.0 cM 53895 13.5 6 2633 Cenpe centromere protein E 1435005_at chr3 H2 229841 13.5 6 2634 Dgcr6 DiGeorge syndrome critical region gene 6 1452434_s_at chr16 B2|16 10.71 cM 13353 13.5 6 2635 Cct7 chaperonin containing Tcp1, subunit 7 (eta) 1415816_at chr6 D1 12468 13.5 6 2636 Hdhd2 haloacid dehalogenase-like hydrolase domain containing 2 1428507_at chr18 E3 76987 13.5 6 2637 Ciapin1 cytokine induced apoptosis inhibitor 1 1448140_at chr8 C5 109006 13.5 6 2638 Cisd1 CDGSH iron sulfur domain 1 1416849_at chr10 B5.3|10 38.0 cM 52637 13.5 6 2639 Lzic leucine zipper and CTNNBIP1 domain containing 1429307_s_at chr4 E2 69151 13.5 6 2640 Asns asparagine synthetase 1451095_at chr6 A1 27053 13.5 6 2641 Esd esterase D/formylglutathione hydrolase 1417825_at chr14 D2-E2|14 41.5 cM 13885 13.5 6 2642 Psmb4 proteasome (prosome, macropain) subunit, beta type 4 1451205_at chr3 F2|3 43.1 cM 19172 13.5 6 2643 Pgk1 phosphoglycerate kinase 1 1417864_at chrX C-D|X 45.0 cM 18655 13.5 6 2644 Nat5 N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae) 1418244_at chr2 H1|2 82.0 cM 67877 13.5 6 2645 Mrps23 mitochondrial ribosomal protein S23 1421874_a_at chr11 C|11 48.0 cM 64656 13.5 6 2646 Ranbp3 RAN binding protein 3 1452673_at chr17 D 71810 13.5 6 2647 Ccnb1 /// Gm5593 /// Gm8416 cyclin B1 /// predicted gene 5593 /// predicted gene 8416 1416076_at chr13 D1 /// chr14 A1 /// chr7 B3 268697 /// 434175 /// 667005 13.5 6 2648 Cdc20 cell division cycle 20 homolog (S. cerevisiae) 1439377_x_at chr4 D2.1 107995 13.5 6 2649 Nudt1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1449349_at chr5 G1 17766 13.5 6 2650 Nob1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1454957_at chr8 D2 67619 13.5 6 2651 Nhp2l1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1416973_at chr15 E1|15 48.0 cM 20826 13.5 6 2652 Gm10080 /// Gm5526 /// Gm8894 /// Myl6 predicted gene 10080 /// myosin, light polypeptide 6, alkali, smooth muscle and non-muscle 1424269_a_at chr1 C1.1 /// chr14 C3 /// chr9 A5.2|9 100043172 /// 17904 /// 433297 /// 667952 13.5 6 2653 Emg1 EMG1 nucleolar protein homolog (S. cerevisiae) 1416393_at chr6 F2|6 60.22 cM 14791 13.5 6 2654 Nhp2l1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1416972_at chr15 E1|15 48.0 cM 20826 13.5 6 2655 Paip2 polyadenylate-binding protein-interacting protein 2 1448493_at chr18 B2 67869 13.5 6 2656 Sac3d1 SAC3 domain containing 1 1417035_at chr19 A 66406 13.5 6 2657 Sri sorcin 1450878_at chr5 A1-h|5 1.0 cM 109552 13.5 6 2658 Ahcy S-adenosylhomocysteine hydrolase 1417125_at chr2 H1|2 89.0 cM 269378 13.5 6 2659 Apoa1bp apolipoprotein A-I binding protein 1415727_at chr3 F1 246703 13.5 6 2660 Ndufb10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10 1428322_a_at chr17 A3.3 68342 13.5 6 2661 LOC100047839 /// Tomm6 hypothetical protein LOC100047839 /// translocase of outer mitochondrial membrane 6 homolog (yeast) 1437336_x_at chr17 C 100047839 /// 66119 13.5 6 2662 Tubg1 tubulin, gamma 1 1417144_at chr11 D|11 60.0 cM 103733 13.5 6 2663 Vps37b vacuolar protein sorting 37B (yeast) 1424380_at chr5 F 330192 13.5 6 2664 Nubpl nucleotide binding protein-like 1429278_at chr12 C1 76826 13.5 6 2665 Mat2a methionine adenosyltransferase II, alpha 1423667_at chr6 C1 232087 13.5 6 2666 Snrnp27 small nuclear ribonucleoprotein 27 (U4/U6.U5) 1460697_s_at chr6 D1 66618 13.5 6 2667 Tsg101 tumor susceptibility gene 101 1417004_at chr7 B5 22088 13.5 6 2668 Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 1422791_at chr9 A5.2 18475 13.5 6 2669 Tmem42 transmembrane protein 42 1421127_at chr9 F4|9 72.0 cM 66079 13.5 6 2670 Tes testis derived transcript 1424246_a_at chr6 A2|6 1.5 cM 21753 13.5 6 2671 Fbxo5 F-box protein 5 1429499_at chr10 A1 67141 13.5 6 2672 Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 1437447_s_at chr7 A3|7 4.0 cM 13870 13.5 6 2673

PAGE 26

Uspl1 ubiquitin specific peptidase like 1 1433927_at chr5 G3 231915 13.5 6 2674 Akr1a4 aldo-keto reductase family 1, member A4 (aldehyde reductase) 1435011_x_at chr4 C7 58810 13.5 6 2675 2610306M01Rik RIKEN cDNA 2610306M01 gene 1452988_at chr6 D1 67170 13.5 6 2676 Prim2 DNA primase, p58 subunit 1418036_at chr1 B|1 18.5 cM 19076 13.5 6 2677 Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 1423826_at chr5 F 100608 13.5 6 2678 Mtf2 metal response element binding transcription factor 2 1418514_at chr5 F 17765 13.5 6 2679 Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 1422610_s_at chr6 B2.3|6 20.3 cM 140488 13.5 6 2680 Mettl2 methyltransferase like 2 1456118_at chr11 E1|11 63.0 cM 52686 13.5 6 2681 Pigy phosphatidylinositol glycan anchor biosynthesis, class Y 1428556_at chr6 B3 66459 13.5 6 2682 BC003266 cDNA sequence BC003266 1449189_at chr4 D2.2 80284 13.5 6 2683 Ldhb lactate dehydrogenase B 1455235_x_at chr6 G2|6 62.0 cM 16832 13.5 6 2684 Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1426384_a_at chr11 B2|11 44.17 cM 22627 13.5 6 2685 Fth1 ferritin heavy chain 1 1448771_a_at chr19 A-C|19 2.0 cM 14319 13.5 6 2686 Gm10241 /// LOC100046167 /// Sumo2 predicted gene 10241 /// similar to Chain B, Crystal Structure Of Sumo-3-Modified Thymine-Dna Glycosylase 1415782_at chr11 E2 /// chr16 A3 100043459 /// 100046167 /// 170930 13.5 6 2687 Sf3b5 splicing factor 3b, subunit 5 1451185_at chr10 A1 66125 13.5 6 2688 Mrpl34 mitochondrial ribosomal protein L34 1416349_at chr8 B3.3|8 33.5 cM 94065 13.5 6 2689 Higd2a HIG1 domain family, member 2A 1418002_at chr13 B1 67044 13.5 6 2690 Ndufa3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 1428464_at chr7 A1 66091 13.5 6 2691 Eif1 eukaryotic translation initiation factor 1 1423799_at chr11 D 20918 13.5 6 2692 Eif4a1 eukaryotic translation initiation factor 4A1 1427058_at chr11 B3|11 39.0 cM 13681 13.5 6 2693 Phc2 polyhomeotic-like 2 (Drosophila) 1437239_x_at chr4 D2.2|4 61.0 cM 54383 13.5 6 2694 Lbr lamin B receptor 1415829_at chr1 H5|1 97.3 cM 98386 13.5 6 2695 Mrpl10 mitochondrial ribosomal protein L10 1418112_at chr11 D 107732 13.5 6 2696 Smoc2 SPARC related modular calcium binding 2 1415935_at chr17 10.0 cM 64074 13.5 6 2697 Slc35b1 solute carrier family 35, member B1 1448769_at chr11 D|11 55.5 cM 110172 13.5 6 2698 Gpr180 G protein-coupled receptor 180 1417245_at chr14 E4 58245 13.5 6 2699 Pfdn4 prefoldin 4 1454888_at chr2 H3|2 99.0 cM 109054 13.5 6 2700 Supt3h suppressor of Ty 3 homolog (S. cerevisiae) 1434963_at chr17 B3 109115 13.5 6 2701 Ctnnbip1 catenin beta interacting protein 1 1431694_a_at chr4 E2 67087 13.5 6 2702 4933434E20Rik RIKEN cDNA 4933434E20 gene 1448463_at chr3 F1 99650 13.5 6 2703 Rps27l ribosomal protein S27-like 1450925_a_at chr9 D 67941 13.5 6 2704 Rfc2 replication factor C (activator 1) 2 1417503_at chr5 G2|5 74.0 cM 19718 13.5 6 2705 Ptp4a2 protein tyrosine phosphatase 4a2 1420613_at chr4 D2.3 19244 13.5 6 2706 Fam100b family with sequence similarity 100, member B 1436747_at chr11 E2 319370 13.5 6 2707 Znhit1 zinc finger, HIT domain containing 1 1451745_a_at chr5 G1 70103 13.5 6 2708 H2afx H2A histone family, member X 1416746_at chr9 A5.2|9 26.0 cM 15270 13.5 6 2709 Map2k6 mitogen-activated protein kinase kinase 6 1426850_a_at chr11 E1 26399 13.5 6 2710 Dusp28 dual specificity phosphatase 28 1429613_at chr1 D 67446 13.5 6 2711 Pbk PDZ binding kinase 1448627_s_at chr14 D1|14 28.0 cM 52033 13.5 6 2712 Fndc4 fibronectin type III domain containing 4 1431226_a_at chr5 B1 64339 13.5 6 2713 Rnf7 ring finger protein 7 1456600_a_at chr9 D2.3 19823 13.5 6 2714 Rnf7 ring finger protein 7 1426414_a_at chr9 D2.3 19823 13.5 6 2715 Snrpb small nuclear ribonucleoprotein B 1437193_s_at chr2 F1|2 73.0 cM 20638 13.5 6 2716 Efcab2 EF-hand calcium binding domain 2 1420513_at chr1 H3 68226 13.5 6 2717 Sepw1 selenoprotein W, muscle 1 1460561_x_at chr7 A2 20364 13.5 6 2718 Nop56 NOP56 ribonucleoprotein homolog (yeast) 1455035_s_at chr2 F3 67134 13.5 6 2719 Bcor BCL6 interacting corepressor 1429438_at chrX A1.2 71458 13.5 6 2720 5730494M16Rik RIKEN cDNA 5730494M16 gene 1459875_x_at chr18 A2 66648 13.5 6 2721 Rpl23 ribosomal protein L23 1415701_x_at chr11 D|11 58.0 cM 65019 13.5 7 2722 Ndufb2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 1416834_x_at chr6 B1 68198 13.5 7 2723 3110082D06Rik RIKEN cDNA 3110082D06 gene 1453598_at chr17 B3 627626 13.5 7 2724 Cycs /// Gm10053 cytochrome c, somatic /// predicted gene 10053 1456071_a_at chr19 B /// chr6 B2.3|6 23.0 cM 13063 /// 672195 13.5 7 2725 Psmb3 proteasome (prosome, macropain) subunit, beta type 3 1417052_at chr11 D|11 58.3 cM 26446 13.5 7 2726 1810046J19Rik RIKEN cDNA 1810046J19 gene 1449412_at chr11 D 103742 13.5 7 2727 Fmc1 formation of mitochondrial complexes 1 homolog (S. cerevisiae) 1416367_at chr6 B1 66117 13.5 7 2728 Cdk4 /// LOC640611 cyclin-dependent kinase 4 /// similar to Cell division protein kinase 4 (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) 1422440_at chr10 D3 12567 /// 640611 13.5 7 2729 Mrpl28 mitochondrial ribosomal protein L28 1456313_x_at chr17 B1 68611 13.5 7 2730 Rpl18 ribosomal protein L18 1450372_a_at chr7 B4 19899 13.5 7 2731 Prkrip1 Prkr interacting protein 1 (IL11 inducible) 1417425_at chr5 G1 66801 13.5 7 2732 1810009A15Rik RIKEN cDNA 1810009A15 gene 1417886_at chr19 A 66276 13.5 7 2733 Kat2a K(lysine) acetyltransferase 2A 1422971_at chr11 D|11 61.4 cM 14534 13.5 7 2734 Hddc3 HD domain containing 3 1428692_at chr7 D3 68695 13.5 7 2735 2610316D01Rik RIKEN cDNA 2610316D01 gene 1458702_at chr3 B 72511 13.5 7 2736 Tmem208 transmembrane protein 208 1419287_at chr8 D1 66320 13.5 7 2737 Rfc4 replication factor C (activator 1) 4 1438161_s_at chr16 B1 106344 13.5 7 2738 Rps17 ribosomal protein S17 1438986_x_at chr7 D3 20068 13.5 7 2739 Gm10333 /// Nutf2 predicted gene 10333 /// nuclear transport factor 2 1434367_s_at chr19 D2 /// chr8 D3|8 52.0 cM 100043462 /// 68051 13.5 7 2740 Magoh mago-nashi homolog, proliferation-associated (Drosophila) 1416212_at chr4 C7|4 51.3 cM 17149 13.5 7 2741 2410015M20Rik RIKEN cDNA 2410015M20 gene 1427909_at chr17 D 224904 13.5 7 2742 LOC100047340 /// Rcc2 hypothetical protein LOC100047340 /// regulator of chromosome condensation 2 1452226_at chr4 D3 100047340 /// 108911 13.5 7 2743 Rangrf RAN guanine nucleotide release factor 1448740_at chr11 B3 57785 13.5 7 2744 Ict1 immature colon carcinoma transcript 1 1460308_a_at chr11 E2 68572 13.5 7 2745 Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 1422460_at chr6 C1|6 30.3 cM 56150 13.5 7 2746 Nudt4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1449107_at --71207 13.5 7 2747 Sin3a Transcriptional regulator, SIN3A (yeast) 1419900_at chr9 B|9 30.0 cM 20466 13.5 7 2748 Trim59 tripartite motif-containing 59 1431430_s_at chr3 E2 66949 13.5 7 2749 Mrps9 mitochondrial ribosomal protein S9 1435843_x_at chr1 B 69527 13.5 7 2750 Cib2 calcium and integrin binding family member 2 1422852_at chr9 A5.3 56506 13.5 7 2751 Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 1423643_at chr8 C2 68278 13.5 7 2752 Gm10709 /// Gm13841 /// Gm5561 /// Gm6344 /// Rpl29 predicted gene 10709 /// predicted gene 13841 /// ribosomal protein L29 1455348_x_at chr1 H4 /// chr13 B1|13 /// chr5 F /// chr9 A1 /// chr9 F2100039782 /// 19944 /// 433941 /// 622707 /// 665032 13.5 7 2753 Chkb choline kinase beta 1448448_a_at chr15 E3 12651 13.5 7 2754 2400001E08Rik RIKEN cDNA 2400001E08 gene 1448718_at chr7 F1 66508 13.5 7 2755 Fis1 fission 1 (mitochondrial outer membrane) homolog (yeast) 1416764_at chr5 G1 66437 13.5 7 2756 Thyn1 thymocyte nuclear protein 1 1438480_a_at chr9 A4 77862 13.5 7 2757 Nudt21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1417681_at chr8 C5 68219 13.5 7 2758 Fzd3 frizzled homolog 3 (Drosophila) 1450135_at chr14 D1|14 27.0 cM 14365 13.5 7 2759 Nkain1 Na+/K+ transporting ATPase interacting 1 1419652_s_at chr4 D3 67149 13.5 7 2760 RP23-195K8.6 hypothetical protein LOC622404 1451370_at chr4 B1 622404 13.5 7 2761 Gm1821 /// Ubb predicted gene 1821 /// ubiquitin B 1453723_x_at chr11 B2|11 35.0 cM /// chr14 C1 22187 /// 624036 13.5 7 2762 Hbxip hepatitis B virus x interacting protein 1415759_a_at chr3 F3 68576 13.5 7 2763 1500009L16Rik RIKEN cDNA 1500009L16 gene 1452840_at chr10 C1 69784 13.5 7 2764 Ndufb7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 1448331_at chr8 C3 66916 13.5 7 2765 Ddah2 dimethylarginine dimethylaminohydrolase 2 1416457_at chr17 B1 51793 13.5 7 2766 Ormdl1 ORM1-like 1 (S. cerevisiae) 1451219_at chr1 C1.1 227102 13.5 7 2767 Gm3258 /// Supt4h1 predicted gene 3258 /// suppressor of Ty 4 homolog 1 (S. cerevisiae) 1422418_s_at chr10 A4 /// chr11 C|11 49.0 cM 100041294 /// 20922 13.5 7 2768 Atp5j2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 1435395_s_at chr5 G2 57423 13.5 7 2769 Atp5c1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 1416058_s_at chr2 A1 11949 13.5 7 2770 Romo1 reactive oxygen species modulator 1 1420642_a_at chr2 H1 67067 13.5 7 2771 Cenpp centromere protein P 1429095_at chr13 B1 66336 13.5 7 2772 Dbf4 DBF4 homolog (S. cerevisiae) 1418334_at chr5 A2 27214 13.5 7 2773 Lsm5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1418656_at chr6 C1 66373 13.5 7 2774 Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 1423779_at chr6 D2 66098 13.5 7 2775 Lypd6 LY6/PLAUR domain containing 6 1454969_at chr2 C1.1 320343 13.5 7 2776 Grpel1 GrpE-like 1, mitochondrial 1417320_at chr5 B3 17713 13.5 7 2777 H2afz H2A histone family, member Z 1438092_x_at chr3 G3 51788 13.5 7 2778 Hoxa5 homeo box A5 1443803_x_at chr6 B3|6 26.3 cM 15402 13.5 7 2779 Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d 1423676_at chr11 E2 71679 13.5 7 2780

PAGE 27

Mrpl40 mitochondrial ribosomal protein L40 1448849_at chr16 A3|16 11.95 cM 18100 13.5 7 2781 Tinf2 Terf1 (TRF1)-interacting nuclear factor 2 1451163_at chr14 C3|14 22.5 cM 28113 13.5 7 2782 Cox6a1 /// Gm7795 cytochrome c oxidase, subunit VI a, polypeptide 1 /// predicted gene 7795 1417418_s_at chr19 A|19 /// chr5 F|5 60.0 cM 12861 /// 665806 13.5 7 2783 Phpt1 phosphohistidine phosphatase 1 1427903_at chr2 A3 75454 13.5 7 2784 Sep15 selenoprotein 1448903_at chr3 H3 93684 13.5 7 2785 Klhl11 kelch-like 11 (Drosophila) 1427218_at chr11 D 217194 13.5 7 2786 1810014B01Rik RIKEN cDNA 1810014B01 gene 1431083_a_at --66263 13.5 7 2787 Atp5g2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 1415980_at chr15 F3 67942 13.5 7 2788 Gm10709 /// Gm12508 /// Gm13841 /// Gm5561 /// Gm6344 /// Rpl29 predicted gene 10709 /// ribosomal protein L29 1448846_a_at chr1 H4 /// chr13 B1|13 /// chr4 B3 /// chr5 F /// chr9 A1 100039782 /// 19944 /// 433941 /// 622707 /// 665032 /// 670211 13.5 7 2789 Ndufs5 NADH dehydrogenase (ubiquinone) Fe-S protein 5 1416495_s_at chr4 D2 595136 13.5 7 2790 Mrps16 mitochondrial ribosomal protein S16 1448869_a_at --66242 13.5 7 2791 Rbp1 retinol binding protein 1, cellular 1448754_at chr9 E3.3|9 52.0 cM 19659 13.5 7 2792 Tes testis derived transcript 1460378_a_at chr6 A2|6 1.5 cM 21753 13.5 7 2793 Lsm1 LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1423873_at chr8 A3 67207 13.5 7 2794 Frs3 fibroblast growth factor receptor substrate 3 1424449_at chr17 C 107971 13.5 7 2795 Gm10333 /// Gm10349 /// Nutf2 predicted gene 10333 /// predicted gene 10349 /// nuclear transport factor 2 1439553_s_at chr18 A1 /// chr19 D2 /// chr8 D3|8 52.0 cM 100043462 /// 621832 /// 68051 13.5 7 2796 OTTMUSG00000010657 predicted gene, OTTMUSG00000010657 1451477_at chr4 E1 666532 13.5 7 2797 Gm6948 /// Gm8942 /// LOC677113 /// Rps24 ribosomal protein S24 pseudogene /// predicted gene 8942 /// similar to ribosomal protein S24 /// ribosomal protein S24 1428530_x_at chr10 D2 /// chr14 B /// chrX B 20088 /// 629116 /// 668041 /// 677113 13.5 7 2798 Bex1 brain expressed gene 1 1448595_a_at chrX F1|X 57.5 cM 19716 13.5 7 2799 Rpl12 ribosomal protein L12 1416026_a_at chr2 B 269261 13.5 7 2800 Ppib peptidylprolyl isomerase B 1437649_x_at chr9 C 19035 13.5 7 2801 Mrpl28 mitochondrial ribosomal protein L28 1416284_at chr17 B1 68611 13.5 7 2802 Cks1b CDC28 protein kinase 1b 1448441_at chr3 F1 54124 13.5 7 2803 Mrpl13 mitochondrial ribosomal protein L13 1424204_at chr15 D2 68537 13.5 7 2804 Mrpl14 mitochondrial ribosomal protein L14 1451307_at chr17 B3 68463 13.5 7 2805 Atp5j2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 1416269_at chr5 G2 57423 13.5 7 2806 Cdca3 cell division cycle associated 3 1452040_a_at chr6 F2|6 60.19 cM 14793 13.5 7 2807 Gm10045 /// Gm10155 /// Gm10163 /// Gm10240 /// Gm12411 /// Gm13653 /// Gm146 predicted gene 10045 /// ribosomal protein L21 pseudogene 1429077_x_at chr15 D2 /// chr17 A3.3 /// chr17 D /// chr18 B3 /// chr2 C 100039601 /// 100040140 /// 100041000 /// 100042767 /// 100043348 /// 1000 13.5 7 2808 2610021K21Rik RIKEN cDNA 2610021K21 gene 1431667_s_at chr12 F1 78767 13.5 7 2809 Gmfg glia maturation factor, gamma 1419193_a_at chr7 A3 63986 13.5 7 2810 Rps24 ribosomal protein S24 1456628_x_at chr14 B 20088 13.5 7 2811 Wipi2 WD repeat domain, phosphoinositide interacting 2 1428882_at chr5 G2 74781 13.5 7 2812 Gm13835 /// Psma3 predicted gene 13835 /// proteasome (prosome, macropain) subunit, alpha type 3 1448442_a_at chr12 C3 /// chr6 A3.3 100038973 /// 19167 13.5 7 2813 Ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4 1438166_x_at chr13 D2.2 17993 13.5 7 2814 Hmgb1 high mobility group box 1 1435324_x_at chr5 G3|5 83.0 cM 15289 13.5 7 2815 Gm10063 /// Gm12334 /// Gm5462 /// Gm7567 /// Gm9153 /// LOC676277 /// Rps12 predicted gene 10063 /// predicted gene 12334 /// ribosomal protein S12 pseudogene 1416453_x_at chr10 A3 /// chr11 B5 /// chr14 D1 /// chr8 A4 /// chrX D / 20042 /// 432865 /// 627835 /// 665281 /// 668406 /// 671641 /// 676277 13.5 7 2816 Gm11970 /// Gm12936 /// Gm6525 /// Gm8001 /// Gm8697 /// Rpl36a predicted gene 11970 /// predicted gene 12936 /// ribosomal protein L36A 1416807_at chr11 A1 /// chr18 D3 /// chr3 F1 /// chr4 D2.2 /// chr7 A1 19982 /// 624713 /// 665197 /// 665277 /// 666243 /// 667549 13.5 7 2817 Tmem183a transmembrane protein 183A 1417200_at chr1 E4 57439 13.5 7 2818 Sfrs3 splicing factor, arginine/serine-rich 3 (SRp20) 1454993_a_at chr17 A3.3|17 11.0 cM 20383 13.5 7 2819 0610012G03Rik RIKEN cDNA 0610012G03 gene 1417002_at chr16 B2 106264 13.5 7 2820 Shfm1 split hand/foot malformation (ectrodactyly) type 1 1418575_at chr6 A2 20422 13.5 7 2821 N6amt2 N-6 adenine-specific DNA methyltransferase 2 (putative) 1449072_a_at chr14 C3 68043 13.5 7 2822 Nsmce2 non-SMC element 2 homolog (MMS21, S. cerevisiae) 1424149_at chr15 D1 68501 13.5 7 2823 Cotl1 coactosin-like 1 (Dictyostelium) 1436236_x_at chr8 E1 72042 13.5 7 2824 2010107E04Rik RIKEN cDNA 2010107E04 gene 1428258_at chr12 F1 70257 13.5 7 2825 Taf10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1448784_at chr7 F1 24075 13.5 7 2826 LOC100047155 /// Snrpa1 similar to Small nuclear ribonucleoprotein polypeptide A /// small nuclear ribonucleoprotein polypeptide A' 1417351_a_at chr7 C 100047155 /// 68981 13.5 7 2827 Tomm20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1423080_at chr8 E2 67952 13.5 7 2828 Arpp19 /// LOC632823 cAMP-regulated phosphoprotein 19 /// similar to cyclic AMP phosphoprotein, 19 kDa 1422608_at chr9 E1 59046 /// 632823 13.5 7 2829 Avpi1 arginine vasopressin-induced 1 1423122_at chr19 C3 69534 13.5 7 2830 LOC100045866 /// Tceb1 similar to elongation factor SIII p15 subunit /// transcription elongation factor B (SIII), polypeptide 1 1427914_a_at chr1 A3 100045866 /// 67923 13.5 7 2831 Mrto4 MRT4, mRNA turnover 4, homolog (S. cerevisiae) 1423823_at chr4 D3 69902 13.5 7 2832 Dpy30 dpy-30 homolog (C. elegans) 1423767_at chr17 E2 66310 13.5 7 2833 Seh1l SEH1-like (S. cerevisiae 1424201_a_at chr18 E1 72124 13.5 7 2834 Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 1455814_x_at chr8 C2 68278 13.5 7 2835 G2e3 G2/M-phase specific E3 ubiquitin ligase 1455355_at chr12 C1 217558 13.5 7 2836 Ndufa2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 1417368_s_at chr18 B2 17991 13.5 7 2837 Lama5 laminin, alpha 5 1427009_at chr2 H4|2 106.0 cM 16776 13.5 7 2838 Nubp1 nucleotide binding protein 1 1418905_at chr16 A1|16 3.4 cM 26425 13.5 7 2839 Lsm6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1437109_s_at chr8 C1 78651 13.5 7 2840 Uqcr ubiquinol-cytochrome c reductase (6.4kD) subunit 1448292_at chr10 C1 66594 13.5 7 2841 Exosc5 exosome component 5 1417167_at chr7 A3|7 6.0 cM 27998 13.5 7 2842 Wrb tryptophan rich basic protein 1460446_at chr16 C4 71446 13.5 7 2843 2400001E08Rik /// Gm5510 RIKEN cDNA 2400001E08 gene /// predicted gene 5510 1417463_a_at chr19 A /// chr7 F1 433216 /// 66508 13.5 7 2844 Rps19 ribosomal protein S19 1449243_a_at chr7 A3 20085 13.5 7 2845 Ppp4c protein phosphatase 4, catalytic subunit 1460288_a_at chr7 F3 56420 13.5 7 2846 Gm9684 predicted gene 9684 1454312_at chr15 E3|15 676575 13.5 7 2847 Tigd5 tigger transposable element derived 5 1460743_at chr15 D3 105734 13.5 7 2848 Tbca tubulin cofactor A 1417652_a_at chr13 D1 21371 13.5 7 2849 Ppil5 peptidylprolyl isomerase (cyclophilin) like 5 1452458_s_at chr12 C3 69706 13.5 7 2850 Orc1l origin recognition complex, subunit 1-like (S.cereviaiae) 1422663_at chr4 D 18392 13.5 7 2851 Sssca1 Sjogren's syndrome/scleroderma autoantigen 1 homolog (human) 1417725_a_at chr19 A 56390 13.5 7 2852 Ptrh2 peptidyl-tRNA hydrolase 2 1451845_a_at chr11 C 217057 13.5 7 2853 Exo1 exonuclease 1 1418026_at chr1 H4|1 97.0 cM 26909 13.5 7 2854 Yeats4 YEATS domain containing 4 1423105_a_at chr10 D2 64050 13.5 7 2855 Prdx1 peroxiredoxin 1 1434731_x_at chr4 D1|4 47.0 cM 18477 13.5 7 2856 Ccdc72 coiled-coil domain containing 72 1454813_at chr9 F2 66167 13.5 7 2857 Nip7 nuclear import 7 homolog (S. cerevisiae) 1448480_at chr8 D2 66164 13.5 7 2858 Aif1l allograft inflammatory factor 1-like 1451287_s_at chr2 B 108897 13.5 7 2859 Chaf1b chromatin assembly factor 1, subunit B (p60) 1423877_at chr16 C4|16 67.4 cM 110749 13.5 7 2860 Cox6b1 cytochrome c oxidase, subunit VIb polypeptide 1 1436757_a_at chr7 B1|7 10.0 cM 110323 13.5 7 2861 Nudt14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 1424753_at chr12 F2 66174 13.5 7 2862 Cklf chemokine-like factor 1425769_x_at chr8 D3 75458 13.5 7 2863 Fxn frataxin 1427282_a_at chr19 C1 14297 13.5 7 2864 Hnrnpc heterogeneous nuclear ribonucleoprotein C 1460240_a_at chr14 C2|14 20.0 cM 15381 13.5 7 2865 Rpl14 ribosomal protein L14 1438626_x_at chr9 F4 67115 13.5 7 2866 Cd151 CD151 antigen 1424093_x_at chr7 F5|7 23.5 cM 12476 13.5 7 2867 AU022252 expressed sequence AU022252 1438226_at chr4 D2.1 230696 13.5 7 2868 Cox17 cytochrome c oxidase, subunit XVII assembly protein homolog (yeast) 1434435_s_at chr16 B3 12856 13.5 7 2869 Uqcrh ubiquinol-cytochrome c reductase hinge protein 1452133_at chr4 C7 66576 13.5 7 2870 Gm10241 /// Gm13430 /// Gm13690 /// LOC100046167 /// Sumo2 predicted gene 10241 /// SMT3 suppressor of mif two 3 homolog 2 (yeast) 1415781_a_at chr11 E2 /// chr16 A3 /// chr2 B /// chr2 C3 100043459 /// 100046167 /// 170930 /// 672381 /// 675440 13.5 7 2871 5730601F06Rik RIKEN cDNA 5730601F06 gene 1454812_at chr9 A3 77519 13.5 7 2872 Cd151 CD151 antigen 1451232_at chr7 F5|7 23.5 cM 12476 13.5 7 2873 2810055G20Rik RIKEN cDNA 2810055G20 gene 1431424_at chr16 C3.1 77994 13.5 7 2874 Med30 mediator complex subunit 30 1448917_at chr15 C 69790 13.5 7 2875 D7Ertd715e DNA segment, Chr 7, ERATO Doi 715, expressed 1455087_at chr7 B5|7 28.65 cM 52480 13.5 7 2876 Tusc2 tumor suppressor candidate 2 1417593_at chr9 F1 80385 13.5 7 2877 Rps24 ribosomal protein S24 1453362_x_at chr14 B 20088 13.5 7 2878 Serf2 small EDRK-rich factor 2 1433786_x_at chr2 E5 378702 13.5 7 2879 Gm3379 /// Gm4892 /// Gm7476 /// Rpl10 predicted gene 3379 /// ribosomal protein 10 pseudogene /// 60S ribosomal protein L10 (QM protein homolog) 1415942_at chr12 B3 /// chr12 F1|12 /// chr8 D3 /// chrX A7.3|X 29.82 100041509 /// 110954 /// 234703 /// 665071 13.5 7 2880 Gm11401 /// LOC638798 /// LOC677628 /// Tceb2 predicted gene 11401 /// similar to transcription elongation factor B (SIII), polypeptide 2 1436949_a_at chr11 A1 /// chr17 A3.3 638798 /// 665250 /// 67673 /// 677628 13.5 7 2881 LOC100045999 /// Ran similar to RAN, member RAS oncogene family /// RAN, member RAS oncogene family 1438977_x_at chr5 G1.3 100045999 /// 19384 13.5 7 2882 Anxa6 Annexin A6 1442288_at chr11 B1.3|11 29.5 cM 11749 13.5 7 2883 Mrps6 mitochondrial ribosomal protein S6 1424440_at chr16 C4 121022 13.5 7 2884 Hmgb1 high mobility group box 1 1425048_a_at chr5 G3|5 83.0 cM 15289 13.5 7 2885 Zfp637 zinc finger protein 637 1434689_at chr6 F1 232337 13.5 7 2886 Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 1460165_at chr19 E3-F2 19045 13.5 7 2887

PAGE 28

Hax1 HCLS1 associated X-1 1426187_a_at --23897 13.5 7 2888 Rps9 ribosomal protein S9 1433689_s_at chr7 A1 76846 13.5 7 2889 9430021M05Rik RIKEN cDNA 9430021M05 gene 1430464_at --77288 13.5 7 2890 Oaz1 ornithine decarboxylase antizyme 1 1436292_a_at chr10 C1|10 43.0 cM 18245 13.5 7 2891 Ppil5 peptidylprolyl isomerase (cyclophilin) like 5 1427506_at chr12 C3 69706 13.5 7 2892 2810025M15Rik RIKEN cDNA 2810025M15 gene 1428452_at chr1 H1 69953 13.5 7 2893 ----1459720_x_at ----13.5 7 2894 Fgfr1op Fgfr1 oncogene partner 1428919_at chr17 A1 75296 13.5 7 2895 Gm13611 /// Gm4604 /// LOC100048508 /// Rpl36 predicted gene 13611 /// predicted gene 4604 /// similar to Rpl36 protein /// ribosomal protein L36 1433510_x_at chr17 D /// chr2 B /// chr6 E1|6 100043718 /// 100048508 /// 54217 /// 622534 13.5 7 2896 Hmgb2 high mobility group box 2 1438307_at chr8 B2 97165 13.5 7 2897 Gm1821 /// Gm8441 /// LOC218963 /// Ubb predicted gene 1821 /// predicted gene 8441 /// ubiquitin pseudogene /// ubiquitin B 1449436_s_at chr11 B2|11 35.0 cM /// chr14 C1 /// chr6 B3 218963 /// 22187 /// 624036 /// 667066 13.5 7 2898 Polr2c polymerase (RNA) II (DNA directed) polypeptide C 1416341_at chr8 D1 20021 13.5 7 2899 Timm23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1416485_at chr14 B 53600 13.5 7 2900 Myo9b Myosin IXb 1459110_at chr8 B3.3|8 33.5 cM 17925 13.5 7 2901 Eef1a2 eukaryotic translation elongation factor 1 alpha 2 1418062_at chr2 H4|2 110.0 cM 13628 13.5 7 2902 Tbpl1 TATA box binding protein-like 1 1431415_a_at chr10 A3 237336 13.5 7 2903 Pdgfa platelet derived growth factor, alpha 1418711_at chr5 G2|5 82.0 cM 18590 13.5 7 2904 Mrps21 mitochondrial ribosomal protein S21 1422451_at chr3 F2 66292 13.5 7 2905 Znhit1 zinc finger, HIT domain containing 1 1425531_at chr5 G1 70103 13.5 7 2906 2010007H12Rik RIKEN cDNA 2010007H12 gene 1429255_at chr5 G2 69871 13.5 7 2907 2810001G20Rik RIKEN cDNA 2810001G20 gene 1455170_at chr11 B3 66456 13.5 7 2908 Cspp1 centrosome and spindle pole associated protein 1 1431405_a_at chr1 A2 211660 13.5 7 2909 Chchd2 /// LOC100045688 /// Scand3 coiled-coil-helix-coiled-coil-helix domain containing 2 /// similar to coiled-coil-helix-coiled-coil-helix domain containing 2 1450815_s_at chr5 G1.3 100045688 /// 14004 /// 71970 13.5 7 2910 Tm2d2 TM2 domain containing 2 1438181_x_at chr8 A3 69742 13.5 7 2911 Chst11 carbohydrate sulfotransferase 11 1450509_at chr10 C1 58250 13.5 7 2912 5133400G04Rik RIKEN cDNA 5133400G04 gene 1430023_at chr18 B3 71242 13.5 7 2913 Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 1438168_x_at chr8 C2 68278 13.5 7 2914 Cox5b cytochrome c oxidase, subunit Vb 1456588_x_at chr1 B 12859 13.5 7 2915 1810043H04Rik RIKEN cDNA 1810043H04 gene 1457826_a_at chr11 E2 208501 13.5 7 2916 Dnajc24 DnaJ (Hsp40) homolog, subfamily C, member 24 1430718_s_at chr2 E3 99349 13.5 7 2917 Ndufb7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 1416417_a_at chr8 C3 66916 13.5 7 2918 Cd151 CD151 antigen 1437670_x_at chr7 F5|7 23.5 cM 12476 13.5 7 2919 D4Ertd22e DNA segment, Chr 4, ERATO Doi 22, expressed 1434482_at chr4 D3|4 69.8 cM 213491 13.5 7 2920 Polr1d polymerase (RNA) I polypeptide D 1459657_s_at chr5 G3 20018 13.5 7 2921 Wdr4 WD repeat domain 4 1423138_at chr17 B1 57773 13.5 7 2922 A430005L14Rik RIKEN cDNA A430005L14 gene 1454682_at chr4 E2 97159 13.5 7 2923 4930558N01Rik RIKEN cDNA 4930558N01 gene 1429586_at --75840 13.5 7 2924 Chchd3 /// LOC100046321 coiled-coil-helix-coiled-coil-helix domain containing 3 /// similar to coiled-coil-helix-coiled-coil-helix domain containing 3 1431241_at chr6 B1 100046321 /// 66075 13.5 7 2925 Naca nascent polypeptide-associated complex alpha polypeptide 1416669_s_at chr10 D2-D3 17938 13.5 7 2926 Ncald neurocalcin delta 1417569_at chr15 B3.1|15 11.0 cM 52589 13.5 7 2927 Slc35b2 solute carrier family 35, member B2 1423927_at chr17 B3 73836 13.5 7 2928 Psmg3 proteasome (prosome, macropain) assembly chaperone 3 1424087_at chr5 G2 66506 13.5 7 2929 D930003E18Rik RIKEN cDNA D930003E18 gene 1440007_at --100048911 13.5 7 2930 Pim2 proviral integration site 2 1417216_at chrX A1.1|X 2.0 cM 18715 13.5 7 2931 Med31 mediator of RNA polymerase II transcription, subunit 31 homolog (yeast) 1417387_at chr11 B4 67279 13.5 7 2932 Tipin timeless interacting protein 1426612_at chr9 D|9 36.0 cM 66131 13.5 7 2933 Nubp1 nucleotide binding protein 1 1430778_a_at chr16 A1|16 3.4 cM 26425 13.5 7 2934 Gm1821 /// Ubb predicted gene 1821 /// ubiquitin B 1435643_x_at chr11 B2|11 35.0 cM /// chr14 C1 22187 /// 624036 13.5 7 2935 Apex1 apurinic/apyrimidinic endonuclease 1 1437715_x_at chr14 C3|14 18.5 cM 11792 13.5 7 2936 Serf2 small EDRK-rich factor 2 1437683_x_at chr2 E5 378702 13.5 7 2937 Gm6573 /// LOC100044992 /// Rps13 ribosomal protein S13 pseudogene /// similar to ribosomal protein S13 /// ribosomal protein S13 1448142_x_at chr7 E1 /// chr8 C3 100044992 /// 625298 /// 68052 13.5 7 2938 Gm10269 /// Gm4342 /// Rpl35 predicted gene 10269 /// predicted gene 4342 /// ribosomal protein L35 1416243_a_at chr18 A2 /// chr2 B /// chr8 E2|8 100040823 /// 100043296 /// 66489 13.5 7 2939 Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1455876_at chr14 A2 218756 13.5 7 2940 Snapin SNAP-associated protein 1426578_s_at chr3 F1 20615 13.5 7 2941 Rpl8 ribosomal protein L8 1417762_a_at chr15 E1 26961 13.5 7 2942 Gtf3a general transcription factor III A 1427027_a_at --66596 13.5 7 2943 Shfm1 split hand/foot malformation (ectrodactyly) type 1 1418574_a_at chr6 A2 20422 13.5 7 2944 Wdr45l Wdr45 like 1416281_at chr11 E2|11 3.4 cM 66840 13.5 7 2945 Slc6a19 solute carrier family 6 (neurotransmitter transporter), member 19 1455442_at chr13 C1 74338 13.5 7 2946 Kcnk1 potassium channel, subfamily K, member 1 1455896_a_at chr8 E2 16525 13.5 7 2947 Fis1 fission 1 (mitochondrial outer membrane) homolog (yeast) 1443819_x_at chr5 G1 66437 13.5 7 2948 Wdr86 WD repeat domain 86 1419464_at chr5 A3 269633 13.5 7 2949 Npr3 natriuretic peptide receptor 3 1450286_at chr15 A1|15 6.7 cM 18162 13.5 7 2950 Ndufb9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 1436803_a_at chr15 D2 66218 13.5 7 2951 Rnaseh2a ribonuclease H2, large subunit 1452725_a_at chr8 C3 69724 13.5 7 2952 Nxt1 NTF2-related export protein 1 1422488_at chr2 H1 56488 13.5 7 2953 Fam109a family with sequence similarity 109, member A 1454662_at chr5 F 231717 13.5 7 2954 Cdc25c cell division cycle 25 homolog C (S. pombe) 1456077_x_at chr18 B1|18 15.0 cM 12532 13.5 7 2955 LOC100046344 /// Nme1 similar to Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) 1424110_a_at chr11 D 100046344 /// 18102 13.5 7 2956 Dtymk deoxythymidylate kinase 1438096_a_at chr1 D|1 38.0 cM 21915 13.5 7 2957 Ccne1 cyclin E1 1416492_at chr7 B2|7 16.0 cM 12447 13.5 7 2958 Msx1 homeobox, msh-like 1 1417127_at chr5 B3|5 21.0 cM 17701 13.5 7 2959 BC027582 cDNA sequence BC027582 1428048_at chr3 F2.2 269472 13.5 7 2960 Alkbh7 alkB, alkylation repair homolog 7 (E. coli) 1428516_a_at chr17 E1.1 66400 13.5 7 2961 Gm10191 /// Gm16382 /// Gm7689 /// LOC638399 /// LOC675018 /// Rpl31 predicted gene 10191 /// ribosomal protein L31 pseudogene 1428212_x_at chr1 B /// chr1 E4 /// chr12 C1 /// chr16 A3 100042740 /// 114641 /// 638399 /// 665562 /// 673582 /// 675018 13.5 7 2962 Serf2 small EDRK-rich factor 2 1435738_x_at chr2 E5 378702 13.5 7 2963 Fam96b family with sequence similarity 96, member B 1428874_at chr8 D1 68523 13.5 7 2964 Ndufa12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 1455806_x_at chr10 F 66414 13.5 7 2965 Cd24a CD24a antigen 1448182_a_at chr10 B2|10 26.0 cM 12484 13.5 7 2966 Serf2 small EDRK-rich factor 2 1455236_x_at chr2 E5 378702 13.5 7 2967 LOC100045999 /// Ran similar to RAN, member RAS oncogene family /// RAN, member RAS oncogene family 1434578_x_at chr5 G1.3 100045999 /// 19384 13.5 7 2968 9430038I01Rik RIKEN cDNA 9430038I01 gene 1453799_at chr7 F4 77252 13.5 7 2969 Raly hnRNP-associated with lethal yellow 1418573_a_at chr2 H1|2 88.8 cM 19383 13.5 7 2970 Nup43 nucleoporin 43 1432187_at chr10 A1 69912 13.5 7 2971 Fastkd2 FAST kinase domains 2 1426741_a_at chr1 C2 75619 13.5 7 2972 Ccne1 cyclin E1 1441910_x_at chr7 B2|7 16.0 cM 12447 13.5 7 2973 Bola1 bolA-like 1 (E. coli) 1452637_a_at chr3 F2 69168 13.5 7 2974 Sub1 SUB1 homolog (S. cerevisiae) 1422693_a_at chr15 A2 20024 13.5 7 2975 Wdr37 WD repeat domain 37 1455278_at chr13 A1 207615 13.5 7 2976 4933434E20Rik RIKEN cDNA 4933434E20 gene 1443955_at chr3 F1 99650 13.5 7 2977 Gpr107 G protein-coupled receptor 107 1459788_at chr2 B 277463 13.5 7 2978 Nmral1 NmrA-like family domain containing 1 1430530_s_at chr16 A1|16 2.5 cM 67824 13.5 7 2979 Sms spermine synthase 1434190_at chrX F4|X 65.45 cM 20603 13.5 7 2980 Cox4i1 cytochrome c oxidase subunit IV isoform 1 1448322_a_at chr8 E1|8 64.0 cM 12857 13.5 7 2981 Rpl23 ribosomal protein L23 1454859_a_at chr11 D|11 58.0 cM 65019 13.5 7 2982 Ccny cyclin Y 1454201_a_at chr18 A1 67974 13.5 7 2983 Tmsb4x thymosin, beta 4, X chromosome 1415906_at chrX F5|X 72.5 cM 19241 13.5 7 2984 Nop10 NOP10 ribonucleoprotein homolog (yeast) 1423211_at chr2 E4 66181 13.5 7 2985 Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1417483_at chr16 C1.2-C1.3 80859 13.5 7 2986 Ep400 E1A binding protein p400 1437020_at chr5 F 75560 13.5 7 2987 Ssbp1 single-stranded DNA binding protein 1 1452616_s_at chr6 B2 381760 13.5 7 2988 Rpl22l1 ribosomal protein L22 like 1 1417126_a_at chr3 A3 68028 13.5 7 2989 Rnf182 ring finger protein 182 1440086_at chr13 A4 328234 13.5 7 2990 Rnaseh2c ribonuclease H2, subunit C 1417427_at chr19 A 68209 13.5 7 2991 Msx1 homeobox, msh-like 1 1448601_s_at chr5 B3|5 21.0 cM 17701 13.5 7 2992 Pole4 polymerase (DNA-directed), epsilon 4 (p12 subunit) 1423372_at chr6 D1 66979 13.5 7 2993 Ppp1r8 protein phosphatase 1, regulatory (inhibitor) subunit 8 1424554_at chr4 D2.3 100336 13.5 7 2994

PAGE 29

Ccdc56 coiled-coil domain containing 56 1423840_at chr11 D|11 60.0 cM 52469 13.5 7 2995 Inpp5j inositol polyphosphate 5-phosphatase J 1433941_at chr11 A1 170835 13.5 7 2996 Cdca5 cell division cycle associated 5 1448466_at chr19 A 67849 13.5 7 2997 Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 1449044_at chr13 A5 66143 13.5 7 2998 Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like 1424766_at chrX D 236930 13.5 7 2999 Fam118b family with sequence similarity 118, member B 1432435_s_at chr9 A5.3 109229 13.5 7 3000 Nt5c3l 5'-nucleotidase, cytosolic III-like 1451180_a_at chr11 D 68106 13.5 7 3001 Sdf4 stromal cell derived factor 4 1426393_a_at chr4 E2 20318 13.5 7 3002 Hmgn1 high mobility group nucleosomal binding domain 1 1455897_x_at chr16 C4|16 69.8 cM 15312 13.5 7 3003 Pole2 polymerase (DNA directed), epsilon 2 (p59 subunit) 1427094_at chr12 C3 18974 13.5 7 3004 Ppie peptidylprolyl isomerase E (cyclophilin E) 1450657_at chr4 D2.2 56031 13.5 7 3005 Cox5b cytochrome c oxidase, subunit Vb 1454716_x_at chr1 B 12859 13.5 7 3006 Cd320 CD320 antigen 1417100_at chr17 B1|17 18.0 cM 54219 13.5 7 3007 Phospho2 phosphatase, orphan 2 1451624_a_at chr2 C2 73373 13.5 7 3008 Prmt1 protein arginine N-methyltransferase 1 1452787_a_at chr7 B4|7 23.1 cM 15469 13.5 7 3009 Dynll1 /// Gm6788 dynein light chain LC8-type 1 /// predicted gene 6788 1417339_a_at chr19 C1 /// chr5 F 56455 /// 627788 13.5 7 3010 Eif3e eukaryotic translation initiation factor 3, subunit E 1434523_x_at chr15 B3.2|15 17.1 cM 16341 13.5 7 3011 Polr2i polymerase (RNA) II (DNA directed) polypeptide I 1428494_a_at chr7 B1 69920 13.5 7 3012 Exo1 exonuclease 1 1418027_at chr1 H4|1 97.0 cM 26909 13.5 7 3013 Prdx1 peroxiredoxin 1 1436691_x_at chr4 D1|4 47.0 cM 18477 13.5 7 3014 Fxc1 fractured callus expressed transcript 1 1436416_x_at chr7 F1 14356 13.5 7 3015 Gm6742 /// Gm7993 /// Gm9115 /// LOC677259 /// Odc1 predicted gene 6742 /// similar to Ornithine decarboxylase (ODC) 1438761_a_at chr12 A1.1 /// chr12 A1.1|12 6.0 cM /// chr5 E3|5 /// chrX 18263 /// 627245 /// 666231 /// 668343 /// 677259 13.5 7 3016 Ccnb1 cyclin B1 1448205_at chr13 D1 268697 13.5 7 3017 Mrps28 mitochondrial ribosomal protein S28 1452585_at chr3 A1 66230 13.5 7 3018 Id3 inhibitor of DNA binding 3 1416630_at chr4 D3|4 66.0 cM 15903 13.5 7 3019 Eif1 eukaryotic translation initiation factor 1 1423798_a_at chr11 D 20918 13.5 7 3020 Cbx2 chromobox homolog 2 (Drosophila Pc class) 1434116_at chr11 E2|11 75.0 cM 12416 13.5 7 3021 Cd151 CD151 antigen 1456085_x_at chr7 F5|7 23.5 cM 12476 13.5 7 3022 Susd4 sushi domain containing 4 1424221_at chr1 H5 96935 13.5 7 3023 Ncaph2 non-SMC condensin II complex, subunit H2 1423698_at chr15 E3|15 49.9 cM 52683 13.5 7 3024 ----1440860_at ----13.5 7 3025 Gtpbp3 GTP binding protein 3 1450980_at chr8 C1 70359 13.5 7 3026 Ndufa12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 1433513_x_at chr10 F 66414 13.5 7 3027 Gm9106 /// Marcksl1 predicted gene 9106 /// MARCKS-like 1 1435627_x_at chr15 F3|15 /// chr4 D2.2|4 59.0 cM 17357 /// 668321 13.5 7 3028 Gng5 guanine nucleotide binding protein (G protein), gamma 5 1423985_at chr3 H2 14707 13.5 7 3029 Ppdpf pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)RIKEN cDNA 2700038C09 gene 1428381_a_at chr2 H4 66496 13.5 7 3030 Sip1 survival of motor neuron protein interacting protein 1 1451044_at chr12 C2 66603 13.5 7 3031 Rnaseh2c ribonuclease H2, subunit C 1439453_x_at chr19 A 68209 13.5 7 3032 Mrpl46 mitochondrial ribosomal protein L46 1449004_at chr7 D3 67308 13.5 7 3033 Mettl11a methyltransferase like 11A 1451278_a_at chr2 B 66617 13.5 7 3034 Traip TRAF-interacting protein 1420707_a_at chr9 F1-F2|9 60.0 cM 22036 13.5 7 3035 D030056L22Rik RIKEN cDNA D030056L22 gene 1455384_x_at chr19 B 225995 13.5 7 3036 Ung uracil DNA glycosylase 1425753_a_at chr5 F 22256 13.5 7 3037 Cars2 cysteinyl-tRNA synthetase 2 (mitochondrial)(putative) 1428524_at chr8 A2 71941 13.5 7 3038 Nup43 nucleoporin 43 1432188_s_at chr10 A1 69912 13.5 7 3039 Refbp2 /// Thoc4 RNA and export factor binding protein 2 /// THO complex 4 1422993_s_at chr1 H3 /// chr11 E2 21681 /// 56009 13.5 7 3040 Ndufs8 NADH dehydrogenase (ubiquinone) Fe-S protein 8 1423908_at chr19 A 225887 13.5 7 3041 Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein 1428235_at chr9 B 66925 13.5 7 3042 Hes6 hairy and enhancer of split 6 (Drosophila) 1452021_a_at chr1 D 55927 13.5 7 3043 Ece2 endothelin converting enzyme 2 1423358_at chr16 B1 107522 13.5 7 3044 Rpl7 ribosomal protein L7 1415979_x_at chr1 A3 19989 13.5 7 3045 Gm10080 /// Gm11836 /// Gm5526 /// Myl6 predicted gene 10080 /// myosin, light polypeptide 6, alkali, smooth muscle and non-muscle 1435041_at chr1 C1.1 /// chr4 A1 /// chr9 A5.2|9 100043172 /// 17904 /// 433297 /// 433688 13.5 7 3046 Timm22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1448518_at chr11 B4 56322 13.5 7 3047 Rac3 RAS-related C3 botulinum substrate 3 1420554_a_at chr11 E2 170758 13.5 7 3048 2700046G09Rik RIKEN cDNA 2700046G09 gene 1431163_at chr19 C1 67188 13.5 7 3049 Ndufb3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 1416547_at chr1 C1.3 66495 13.5 7 3050 Pabpn1 poly(A) binding protein, nuclear 1 1422849_a_at chr14 C3|14 19.5 cM 54196 13.5 7 3051 Gm10333 /// Gm10349 /// Nutf2 predicted gene 10333 /// predicted gene 10349 /// nuclear transport factor 2 1418274_at chr18 A1 /// chr19 D2 /// chr8 D3|8 52.0 cM 100043462 /// 621832 /// 68051 13.5 7 3052 Bloc1s1 biogenesis of lysosome-related organelles complex-1, subunit 1 1422614_s_at chr10 D3|10 72.0 cM 14533 13.5 7 3053 Gnb1l guanine nucleotide binding protein (G protein), beta polypeptide 1-like 1419316_s_at chr16 A3|16 11.28 cM 13972 13.5 7 3054 Sergef secretion regulating guanine nucleotide exchange factor 1419217_at chr7 B4 27414 13.5 7 3055 Ndufa1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 1422241_a_at chrX A2 54405 13.5 7 3056 Gm15365 /// Tomm20 predicted gene 15365 /// translocase of outer mitochondrial membrane 20 homolog (yeast) 1423079_a_at chr8 E2 /// chrX A7.3 546321 /// 67952 13.5 7 3057 5830454E08Rik RIKEN cDNA 5830454E08 gene 1442415_at chr9 F4 76100 13.5 7 3058 Cox6b1 cytochrome c oxidase, subunit VIb polypeptide 1 1416565_at chr7 B1|7 10.0 cM 110323 13.5 7 3059 Pdcd2 programmed cell death 2 1423534_at chr17 A2|17 8.26 cM 18567 13.5 7 3060 Commd3 COMM domain containing 3 1433539_at chr2 A3|2 9.0 cM 12238 13.5 7 3061 Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 1455988_a_at chr5 G1.3 12466 13.5 7 3062 Zscan21 Zinc finger and SCAN domain containing 21 1420096_at chr5 G2|5 78.0 cM 22697 13.5 7 3063 Bcar1 breast cancer anti-estrogen resistance 1 1439388_s_at chr8 D3 12927 13.5 7 3064 2900053A13Rik RIKEN cDNA 2900053A13 gene 1453207_at chr8 A1.1 554362 13.5 7 3065 Tk1 thymidine kinase 1 1416258_at chr11 E1-E2|11 78.0 cM 21877 13.5 7 3066 Ubl4 ubiquitin-like 4 1424538_at chrX A7.3|X 29.9 cM 27643 13.5 7 3067 Mrps7 mitchondrial ribosomal protein S7 1453725_a_at chr11 E2 50529 13.5 7 3068 Atp6v1f ATPase, H+ transporting, lysosomal V1 subunit F 1423993_at chr6 A3 66144 13.5 7 3069 1700029F09Rik RIKEN cDNA 1700029F09 gene 1428593_at chr1 C1|1 75623 13.5 7 3070 Psma6 proteasome (prosome, macropain) subunit, alpha type 6 1416506_at chr12 C1 26443 13.5 7 3071 Atp5g3 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 3 1454661_at chr2 C3 228033 13.5 7 3072 Marcksl1 MARCKS-like 1 1435415_x_at chr4 D2.2|4 59.0 cM 17357 13.5 7 3073 Pebp1 phosphatidylethanolamine binding protein 1 1438649_x_at chr5 F|5 63.0 cM 23980 13.5 7 3074 Rnaseh2c ribonuclease H2, subunit C 1435733_x_at chr19 A 68209 13.5 7 3075 Phb prohibitin 1417053_at chr11 D|11 55.6 cM 18673 13.5 7 3076 Fbxo46 F-box protein 46 1436601_at chr7 A3 243867 13.5 7 3077 Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1435651_a_at chr6 C1|6 29.69 cM 13990 13.5 7 3078 AI428936 expressed sequence AI428936 1427176_s_at chr7 B1 233066 13.5 7 3079 Urm1 ubiquitin related modifier 1 homolog (S. cerevisiae) 1431752_a_at chr2 B 68205 13.5 7 3080 Mrps36 mitochondrial ribosomal protein S36 1423242_at chr13 D1 66128 13.5 7 3081 Nkain1 Na+/K+ transporting ATPase interacting 1 1449553_at chr4 D3 67149 13.5 7 3082 Cd40 CD40 antigen 1460415_a_at chr2 H3|2 97.0 cM 21939 13.5 7 3083 Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 1417233_at chr6 D1 72170 13.5 7 3084 4930515G01Rik RIKEN cDNA 4930515G01 gene 1438869_at chr5 F 67642 13.5 7 3085 Banf1 barrier to autointegration factor 1 1421083_x_at chr19 A 23825 13.5 7 3086 Mll3 myeloid/lymphoid or mixed-lineage leukemia 3 1457193_at chr5 A3 231051 13.5 7 3087 Gtf2h5 general transcription factor IIH, polypeptide 5 1428906_at chr17 A1 66467 13.5 7 3088 Rbbp4 retinoblastoma binding protein 4 1434892_x_at --19646 13.5 7 3089 Lyplal1 lysophospholipase-like 1 1451490_at chr1 H5 226791 13.5 7 3090 Dynll1 /// Gm6788 dynein light chain LC8-type 1 /// predicted gene 6788 1456125_a_at chr19 C1 /// chr5 F 56455 /// 627788 13.5 7 3091 Prim2 DNA primase, p58 subunit 1418035_a_at chr1 B|1 18.5 cM 19076 13.5 7 3092 Banf1 barrier to autointegration factor 1 1421081_a_at chr19 A 23825 13.5 7 3093 Rps27l ribosomal protein S27-like 1423254_x_at chr9 D 67941 13.5 7 3094 Tm2d2 TM2 domain containing 2 1433473_x_at chr8 A3 69742 13.5 7 3095 Cript cysteine-rich PDZ-binding protein 1423486_at chr17 E4 56724 13.5 7 3096 Gm7083 /// Sfrs3 predicted gene 7083 /// splicing factor, arginine/serine-rich 3 (SRp20) 1434512_x_at chr15 D1|15 /// chr17 A3.3|17 11.0 cM 20383 /// 632248 13.5 7 3097 Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 1415958_at chr11 C-E1|11 40.0 cM 20528 13.5 7 3098 Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 1437052_s_at chr6 F2|6 59.0 cM 20527 13.5 7 3099 Glrx3 glutaredoxin 3 1417340_at chr7 F5 30926 13.5 7 3100 Wbp5 WW domain binding protein 5 1451230_a_at chrX F1 22381 13.5 7 3101

PAGE 30

Flywch2 FLYWCH family member 2 1424494_s_at chr17 A3.3 76917 13.5 7 3102 Eri2 exoribonuclease 2 1435390_at chr7 F3|7 71151 13.5 7 3103 0610011L14Rik RIKEN cDNA 0610011L14 gene 1437835_a_at chr2 H2 68295 13.5 7 3104 Mdk midkine 1416006_at chr2 E1|2 53.0 cM 17242 13.5 7 3105 Sms spermine synthase 1421052_a_at chrX F4|X 65.45 cM 20603 13.5 7 3106 Donson downstream neighbor of SON 1426739_at chr16 C3.3 60364 13.5 7 3107 Ldhb lactate dehydrogenase B 1448237_x_at chr6 G2|6 62.0 cM 16832 13.5 7 3108 Pin1 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 1416228_at chr9 A3|9 4.0 cM 23988 13.5 7 3109 Pomp proteasome maturation protein 1416979_at chr5 G3 66537 13.5 7 3110 Itgb1bp1 integrin beta 1 binding protein 1 1422157_a_at chr12 A1.2 16413 13.5 7 3111 Fkbp3 FK506 binding protein 3 1416859_at chr12 C3 30795 13.5 7 3112 Mrpl41 mitochondrial ribosomal protein L41 1428589_at chr2 A3 107733 13.5 7 3113 Ndufs8 NADH dehydrogenase (ubiquinone) Fe-S protein 8 1434579_x_at chr19 A 225887 13.5 7 3114 Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1421751_a_at chr2 C1.3 59029 13.5 7 3115 Dnajc9 DnaJ (Hsp40) homolog, subfamily C, member 9 1426473_at chr14 A3 108671 13.5 7 3116 Krtcap2 keratinocyte associated protein 2 1417058_a_at chr3 F2 66059 13.5 7 3117 Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 1424118_a_at chr2 C3 66442 13.5 7 3118 Rfc3 replication factor C (activator 1) 3 1432538_a_at --69263 13.5 7 3119 Gabra4 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 1433707_at chr5 C3.2 14397 13.5 7 3120 Dsg2 desmoglein 2 1425619_s_at chr18 A2|18 7.05 cM 13511 13.5 7 3121 5730403M16Rik RIKEN cDNA 5730403M16 gene 1434343_at chr7 A1 232853 13.5 7 3122 3200002M19Rik RIKEN cDNA 3200002M19 gene 1424327_at chr7 E3 75430 13.5 7 3123 Uqcrh ubiquinol-cytochrome c reductase hinge protein 1453229_s_at chr4 C7 66576 13.5 7 3124 Sdf2l1 stromal cell-derived factor 2-like 1 1418206_at chr16 A3 64136 13.5 7 3125 Rpl7 ribosomal protein L7 1426162_a_at chr1 A3 19989 13.5 7 3126 Cdk2ap1 /// LOC100047490 CDK2 (cyclin-dependent kinase 2)-associated protein 1 /// similar to putative oral cancer suppressor 1426885_a_at chr5 F 100047490 /// 13445 13.5 7 3127 0610010F05Rik RIKEN cDNA 0610010F05 gene 1456660_a_at chr11 A3.3 71675 13.5 7 3128 Commd6 COMM domain containing 6 1435863_at chr14 E2.3 66200 13.5 7 3129 Bud31 BUD31 homolog (yeast) 1439466_s_at chr5 G2 231889 13.5 7 3130 Ssu72 Ssu72 RNA polymerase II CTD phosphatase homolog (yeast) 1425674_a_at chr4 E2 68991 13.5 7 3131 Ndufs8 NADH dehydrogenase (ubiquinone) Fe-S protein 8 1455283_x_at chr19 A 225887 13.5 7 3132 LOC100048449 /// Rpl18 similar to ribosomal protein L18 /// ribosomal protein L18 1436699_x_at chr7 B4 100048449 /// 19899 13.5 7 3133 Prelid1 PRELI domain containing 1 1431421_x_at chr13 B2 66494 13.5 7 3134 Cdca2 cell division cycle associated 2 1455983_at chr14 D1 108912 13.5 7 3135 Cdc34 /// LOC100046898 cell division cycle 34 homolog (S. cerevisiae) /// similar to Cell division cycle 34 homolog (S. cerevisiae) 1434879_at chr10 C1|10 43.0 cM 100046898 /// 216150 13.5 7 3136 Hmgb3 high mobility group box 3 1416155_at chrX A1 15354 13.5 7 3137 Prdx2 peroxiredoxin 2 1430979_a_at chr8 C3|8 36.0 cM 21672 13.5 7 3138 LOC100045306 /// Med10 similar to mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae) 1448295_at chr13 C1|13 41.0 cM 100045306 /// 28077 13.5 7 3139 Dtymk deoxythymidylate kinase 1452681_at chr1 D|1 38.0 cM 21915 13.5 7 3140 Arf5 /// LOC100046958 ADP-ribosylation factor 5 /// similar to ADP-ribosylation factor 1422807_at chr6 A3.3 100046958 /// 11844 13.5 7 3141 Tmem183a transmembrane protein 183A 1431304_a_at chr1 E4 57439 13.5 7 3142 Cdk2ap1 /// LOC100047490 CDK2 (cyclin-dependent kinase 2)-associated protein 1 /// similar to putative oral cancer suppressor 1456314_x_at chr5 F 100047490 /// 13445 13.5 7 3143 2310028O11Rik RIKEN cDNA 2310028O11 gene 1455126_x_at chr4 D3 433771 13.5 7 3144 AU016916 expressed sequence AU016916 1420083_at --105268 13.5 7 3145 Mrps14 mitochondrial ribosomal protein S14 1420489_at chr1 H2.1 64659 13.5 7 3146 Phgdh 3-phosphoglycerate dehydrogenase 1426658_x_at chr3 E1 236539 13.5 7 3147 Mrps6 mitochondrial ribosomal protein S6 1447585_s_at chr16 C4 121022 13.5 7 3148 Gemin7 gem (nuclear organelle) associated protein 7 1435764_a_at chr7 A3 69731 13.5 7 3149 2900092E17Rik RIKEN cDNA 2900092E17 gene 1424014_at chr7 F4 67278 13.5 7 3150 Slc25a19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 1424316_at chr11 E2 67283 13.5 7 3151 Dph3 DPH3 homolog (KTI11, S. cerevisiae) 1433921_s_at chr14 B 105638 13.5 7 3152 Gm5366 /// Tuba3a /// Tuba3b predicted gene 5366 /// tubulin, alpha 3A /// tubulin, alpha 3B 1416311_s_at chr6 F3 /// chr6 G3 /// chr9 D 22144 /// 22147 /// 384954 13.5 7 3153 Gm11560 /// Gm6540 /// LOC100045189 /// LOC677262 /// Ybx1 CCAAT-binding protein /// predicted gene 6540 /// similar to transcription factor EF1(A) 1418624_at chr11 D /// chr17 A3.3 /// chr4 D1 100045189 /// 22608 /// 624960 /// 630936 /// 677262 13.5 7 3154 Mrpl22 mitochondrial ribosomal protein L22 1435995_at chr11 B1.3 216767 13.5 7 3155 2610209A20Rik RIKEN cDNA 2610209A20 gene 1423357_at chr7 F1 67164 13.5 7 3156 Rabl4 RAB, member of RAS oncogene family-like 4 1434299_x_at chr15 E2 67042 13.5 7 3157 Hax1 HCLS1 associated X-1 1438180_x_at --23897 13.5 7 3158 Etf1 Eukaryotic translation termination factor 1 1449701_at chr18 B1 225363 13.5 7 3159 Timm8b translocase of inner mitochondrial membrane 8 homolog b (yeast) 1431665_a_at chr9 B 30057 13.5 7 3160 Tbca tubulin cofactor A 1456205_x_at chr13 D1 21371 13.5 7 3161 Mif macrophage migration inhibitory factor 1416335_at chr10 C1|10 40.9 cM 17319 13.5 7 3162 LOC100270747 hypothetical LOC100270747 1434391_at --100270747 13.5 7 3163 Ndufa7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a) 1436567_a_at chr17 B1 66416 13.5 7 3164 Dynlt1 /// Dynlt1-ps1 /// LOC100040563 dynein light chain Tctex-type 1 /// dynein light chain Tctex-type 1, pseudogene 1 1453473_a_at chr17 A1 /// chr17 A1|17 3.1 cM /// chr6 G1 100040563 /// 100043890 /// 21648 13.5 7 3165 Aldh16a1 aldehyde dehydrogenase 16 family, member A1 1447372_at chr7 B4 69748 13.5 7 3166 Pafah1b3 platelet-activating factor acetylhydrolase, isoform 1b, subunit 3 1416410_at chr7 A3 18476 13.5 7 3167 Ccdc56 coiled-coil domain containing 56 1419812_s_at chr11 D|11 60.0 cM 52469 13.5 7 3168 Rbm4 RNA binding motif protein 4 1416920_at chr19 A 19653 13.5 7 3169 Mcat malonyl CoA:ACP acyltransferase (mitochondrial) 1452216_at chr15 E1 223722 13.5 7 3170 Mea1 male enhanced antigen 1 1416810_at chr17 C|17 24.3 cM 17256 13.5 7 3171 5730437N04Rik RIKEN cDNA 5730437N04 gene 1424045_at chr17 A1 70544 13.5 7 3172 Tars2 threonyl-tRNA synthetase 2, mitochondrial (putative) 1436856_x_at chr3 F2.1 71807 13.5 7 3173 Gm11663 /// Gm2992 /// Gm7862 /// Hmgn1 predicted gene 11663 /// high mobility group nucleosomal binding domain 1 1438940_x_at chr11 E1 /// chr12 C3 /// chr16 C4|16 69.8 cM /// chr3 E1|3 100040836 /// 15312 /// 665957 /// 666721 13.5 7 3174 Bloc1s2 biogenesis of lysosome-related organelles complex-1, subunit 2 1429048_at chr19 C3 73689 13.5 7 3175 Zfp64 zinc finger protein 64 1430117_a_at chr2 H3|2 98.0 cM 22722 13.5 7 3176 Dph3 DPH3 homolog (KTI11, S. cerevisiae) 1455268_at chr14 B 105638 13.5 7 3177 Tmem223 transmembrane protein 223 1416628_at chr19 A 66836 13.5 7 3178 LOC100044980 /// Thoc7 similar to Thoc7 protein /// THO complex 7 homolog (Drosophila) 1448461_a_at chr14 A2 100044980 /// 66231 13.5 7 3179 Hhipl1 hedgehog interacting protein-like 1 1430062_at chr12 F1 214305 13.5 7 3180 Tspan13 tetraspanin 13 1460239_at chr12 B2 66109 13.5 7 3181 Slc25a38 solute carrier family 25, member 38 1424418_at chr9 F4 208638 13.5 7 3182 1190007I07Rik /// 1810014B01Rik RIKEN cDNA 1190007I07 gene /// RIKEN cDNA 1810014B01 gene 1429259_a_at chr10 C1 544717 /// 66263 13.5 7 3183 Axin1 /// LOC100047927 axin 1 /// similar to Axin 1426967_at chr17 A3.3|17 11.8 cM 100047927 /// 12005 13.5 7 3184 B9d2 B9 protein domain 2 1427947_at chr7 A3 232987 13.5 7 3185 Gpn1 GPN-loop GTPase 1 1442114_at chr5 B1 74254 13.5 7 3186 Stmn1 stathmin 1 1415849_s_at chr4 D3|4 65.7 cM 16765 13.5 7 3187 Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 1427213_at chrX F2 18639 13.5 7 3188 Bnc1 basonuclin 1 1424890_at chr7 D3 12173 13.5 7 3189 Gins1 GINS complex subunit 1 (Psf1 homolog) 1452598_at chr2 H1 69270 13.5 7 3190 C630043F03Rik RIKEN cDNA C630043F03 gene 1455542_at --68285 13.5 7 3191 Siva1 SIVA1, apoptosis-inducing factor 1426323_x_at chr12 F2 30954 13.5 7 3192 Ndufb2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 1448483_a_at chr6 B1 68198 13.5 7 3193 Ndufb9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 1452184_at chr15 D2 66218 13.5 7 3194 Luc7l Luc7 homolog (S. cerevisiae)-like 1431181_a_at chr17 B1|17 11.8 cM 66978 13.5 7 3195 Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 1455898_x_at chr6 F2|6 59.0 cM 20527 13.5 7 3196 Rpl26 ribosomal protein L26 1448109_a_at chr11 B3 19941 13.5 7 3197 H2afv H2A histone family, member V 1436596_at chr11 A1 77605 13.5 7 3198 AI846148 expressed sequence AI846148 1438270_at chr19 A 68229 13.5 7 3199 Eef1b2 eukaryotic translation elongation factor 1 beta 2 1448252_a_at chr1 C2 55949 13.5 7 3200 Ccl25 chemokine (C-C motif) ligand 25 1458277_at chr8 A1.1|8 1.0 cM 20300 13.5 7 3201 Siva1 SIVA1, apoptosis-inducing factor 1452020_a_at chr12 F2 30954 13.5 7 3202 2010111I01Rik RIKEN cDNA 2010111I01 gene 1460695_a_at chr13 B3 72061 13.5 7 3203 Cks1b CDC28 protein kinase 1b 1416698_a_at chr3 F1 54124 13.5 7 3204 Pcbd2 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 1452621_at chr13 B2 72562 13.5 7 3205 Rpl34 ribosomal protein L34 1427875_a_at chr3 G3 68436 13.5 7 3206 Ndufab1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 1428160_at chr7 F3 70316 13.5 7 3207 Brms1 breast cancer metastasis-suppressor 1 1426129_at chr19 A 107392 13.5 7 3208

PAGE 31

LOC676546 /// Mmd similar to monocyte to macrophage differentiation-associated 1435645_at chr11 C 67468 /// 676546 13.5 7 3209 Ero1l /// Rpl31 ERO1-like (S. cerevisiae) /// ribosomal protein L31 1460008_x_at chr1 B /// chr14 C-D 114641 /// 50527 13.5 7 3210 Sgol1 shugoshin-like 1 (S. pombe) 1418919_at chr17 C 72415 13.5 7 3211 Cox8a cytochrome c oxidase, subunit VIIIa 1448222_x_at chr19 A 12868 13.5 7 3212 Ero1l /// Gm10191 /// Gm13004 /// Gm16382 /// Gm7689 /// Gm9401 /// LOC638399 ERO1-like (S. cerevisiae) /// predicted gene 10191 /// ribosomal protein L31 pseudogene 1436924_x_at chr1 B /// chr1 E4 /// chr12 C1 /// chr14 C-D /// chr16 A3 100042740 /// 114641 /// 50527 /// 638399 /// 665533 /// 665562 /// 668850 13.5 7 3213 Erdr1 erythroid differentiation regulator 1 1452406_x_at --170942 13.5 7 3214 Sap30 sin3 associated polypeptide 1417719_at chr8 B2|8 31.0 cM 60406 13.5 7 3215 Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1424151_at chr5 G2 231872 13.5 7 3216 Sf3b4 splicing factor 3b, subunit 4 1436784_x_at chr3 F2.1 107701 13.5 7 3217 Gm6573 /// Gm6834 /// LOC100044992 /// Rps13 ribosomal protein S13 pseudogene /// predicted gene 6834 1415912_a_at chr7 E1 /// chr8 C3 /// chr8 E1 100044992 /// 625298 /// 628061 /// 68052 13.5 7 3218 Clcn7 chloride channel 7 1450408_at chr17 A3.3|17 10.0 cM 26373 13.5 7 3219 Sod1 superoxide dismutase 1, soluble 1451124_at chr16 B5-C3|16 61.0 cM 20655 13.5 7 3220 Ndufs5 NADH dehydrogenase (ubiquinone) Fe-S protein 5 1416494_at chr4 D2 595136 13.5 7 3221 Nmral1 NmrA-like family domain containing 1 1453562_a_at chr16 A1|16 2.5 cM 67824 13.5 7 3222 Prdx4 peroxiredoxin 4 1416167_at chrX F3|X 67.7 cM 53381 13.5 7 3223 Sod1 superoxide dismutase 1, soluble 1459976_s_at chr16 B5-C3|16 61.0 cM 20655 13.5 7 3224 Grcc10 gene rich cluster, C10 gene 1416522_a_at chr6 F2|6 60.22 cM 14790 13.5 7 3225 Gm11627 predicted gene 11627 1442917_at chr11 E1 100040792 13.5 7 3226 Gm9354 /// LOC100042019 /// Rps27a predicted gene 9354 /// similar to fusion protein: ubiquitin (bases 43_513) 1449196_a_at chr11 A3.3 /// chr7 B5 100042019 /// 668779 /// 78294 13.5 7 3227 Rps17 ribosomal protein S17 1455662_x_at chr7 D3 20068 13.5 7 3228 EG627427 /// Gm13337 /// Gm5385 /// Gm7669 /// Gm7901 /// Gm8096 /// Gm8341 / predicted gene, EG627427 /// 3-phosphoglycerate dehydrogenase pseudogene 1456471_x_at chr15 A2|15 /// chr17 C /// chr18 B2|18 /// chr2 A3 /// chr 236539 /// 385344 /// 627427 /// 630761 /// 630896 /// 637235 /// 665516 / 13.5 7 3229 Cox8a cytochrome c oxidase, subunit VIIIa 1416112_at chr19 A 12868 13.5 7 3230 Bola2 bolA-like 2 (E. coli) 1434544_at chr7 F3 66162 13.5 7 3231 Snrpc U1 small nuclear ribonucleoprotein C 1416197_at chr17 B1 20630 13.5 7 3232 Gm7669 /// Gm7901 /// Gm9347 /// Phgdh predicted gene 7669 /// 3-phosphoglycerate dehydrogenase 1454714_x_at chr3 E1 /// chr7 F3|7 /// chr8 A1.1 /// chr8 C1 236539 /// 665516 /// 666036 /// 668771 13.5 7 3233 Wnt6 wingless-related MMTV integration site 6 1435980_x_at chr1 C3 22420 13.5 7 3234 Zfp719 zinc finger protein 719 1443985_at chr7 B4 210105 13.5 7 3235 Cox7c /// Gm10012 /// Gm3386 /// LOC100048613 cytochrome c oxidase, subunit VIIc /// cytochrome c oxidase, subunit VIIc pseudogene 1448112_at chr13 C3 /// chr14 B|14 /// chr17 A3.3 100041521 /// 100043160 /// 100048613 /// 12867 13.5 7 3236 Aff4 AF4/FMR2 family, member 4 1420912_at chr11 B1.3 93736 13.5 7 3237 Dynlt1 /// Dynlt1-ps1 /// LOC100040563 dynein light chain Tctex-type 1 /// dynein light chain Tctex-type 1, pseudogene 1 1428116_a_at chr17 A1 /// chr17 A1|17 3.1 cM /// chr6 G1 100040563 /// 100043890 /// 21648 13.5 7 3238 Rps24 ribosomal protein S24 1436064_x_at chr14 B 20088 13.5 7 3239 ----1445518_at ----13.5 7 3240 Stra13 stimulated by retinoic acid 13 1416553_at chr11 E2 20892 13.5 7 3241 Psmb6 proteasome (prosome, macropain) subunit, beta type 6 1448822_at chr11 B3|11 39.0 cM 19175 13.5 7 3242 Gpx4 glutathione peroxidase 4 1456193_x_at chr10 C1|10 43.0 cM 625249 13.5 7 3243 Nop10 NOP10 ribonucleoprotein homolog (yeast) 1423210_a_at chr2 E4 66181 13.5 7 3244 2810004N23Rik /// Setd6 RIKEN cDNA 2810004N23 gene /// SET domain containing 6 1448947_at chr8 D1 /// chr8 E2 66083 /// 66523 13.5 7 3245 1110020P15Rik RIKEN cDNA 1110020P15 gene 1424364_a_at chr11 A1 66152 13.5 7 3246 Mlh1 mutL homolog 1 (E. coli) 1417360_at chr9 F3|9 62.0 cM 17350 13.5 7 3247 Prss16 protease, serine, 16 (thymus) 1448355_at chr13 A3-A5|13 10.0 cM 54373 13.5 7 3248 Gcsh glycine cleavage system protein H (aminomethyl carrier) 1432164_a_at chr8 E1 68133 13.5 7 3249 Bex2 brain expressed X-linked 2 1417388_at chrX F1|X 57.5 cM 12069 13.5 7 3250 Tmem121 transmembrane protein 121 1451181_at chr12 F1 69195 13.5 7 3251 Cox6a1 cytochrome c oxidase, subunit VI a, polypeptide 1 1417417_a_at chr5 F|5 60.0 cM 12861 13.5 7 3252 Gpx1 glutathione peroxidase 1 1460671_at chr9 F1|9 57.0 cM 14775 13.5 7 3253 Siva1 SIVA1, apoptosis-inducing factor 1418377_a_at chr12 F2 30954 13.5 7 3254 Trip13 thyroid hormone receptor interactor 13 1429295_s_at chr13 C1|13 43.0 cM 69716 13.5 7 3255 Csrp2 cysteine and glycine-rich protein 2 1420731_a_at chr10 D1 13008 13.5 7 3256 Mrpl28 mitochondrial ribosomal protein L28 1437622_x_at chr17 B1 68611 13.5 7 3257 Aprt adenine phosphoribosyl transferase 1423801_a_at chr8 E1|8 67.0 cM 11821 13.5 7 3258 Rps20 ribosomal protein S20 1456436_x_at chr4 A1 67427 13.5 7 3259 Tm2d2 TM2 domain containing 2 1437725_x_at chr8 A3 69742 13.5 7 3260 Naca nascent polypeptide-associated complex alpha polypeptide 1448430_a_at chr10 D2-D3 17938 13.5 7 3261 Mrpl1 mitochondrial ribosomal protein L1 1450948_a_at chr5 E3 94061 13.5 7 3262 Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein 1425271_at chr11 D 19183 13.5 7 3263 Ttc39a tetratricopeptide repeat domain 39A 1455162_at chr4 C7 230603 13.5 7 3264 Med11 mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae) 1417739_at chr11 B3 66172 13.5 7 3265 LOC100045999 /// LOC640204 /// Ran similar to RAN, member RAS oncogene family /// 1439270_x_at chr5 G1.3 100045999 /// 19384 /// 640204 13.5 7 3266 Hmgn2 high mobility group nucleosomal binding domain 2 1433507_a_at chr4 D3|4 62.2 cM 15331 13.5 7 3267 Prdx2 peroxiredoxin 2 1418506_a_at chr8 C3|8 36.0 cM 21672 13.5 7 3268 Rps8 ribosomal protein S8 1437610_x_at chr4 D1 20116 13.5 7 3269 Metrn meteorin, glial cell differentiation regulator 1427100_at chr17 A3.3 70083 13.5 7 3270 Airn antisense Igf2r RNA 1451634_at chr17 A1|17 7.36 cM 104103 13.5 7 3271 Cdc26 cell division cycle 26 1423987_at chr4 B3 66440 13.5 7 3272 Etnk1 ethanolamine kinase 1 1439972_at chr6 G3|6 74.0 cM 75320 13.5 7 3273 Marveld2 MARVEL (membrane-associating) domain containing 2 1426914_at chr13 D1 218518 13.5 7 3274 Cox5a cytochrome c oxidase, subunit Va 1415933_a_at chr9 B 12858 13.5 7 3275 Cdk4 cyclin-dependent kinase 4 1422441_x_at chr10 D3 12567 13.5 7 3276 Fam136a family with sequence similarity 136, member A 1417075_at chr6 D1 66488 13.5 7 3277 Prss22 protease, serine, 22 1420352_at chr17 A3.3|17 10.7 cM 70835 13.5 7 3278 Sec61b Sec61 beta subunit 1417083_at chr4 B1 66212 13.5 7 3279 Gm6722 /// H2afz predicted gene 6722 /// H2A histone family, member Z 1438091_a_at chr12 D1 /// chr3 G3 51788 /// 626950 13.5 7 3280 Rpl35 ribosomal protein L35 1454856_x_at chr2 B 66489 13.5 7 3281 Tbc1d9 TBC1 domain family, member 9 1431253_s_at chr8 C3 71310 13.5 7 3282 1110034G24Rik RIKEN cDNA 1110034G24 gene 1452888_at --73747 13.5 7 3283 Gm12967 /// Gm4468 /// Rpl37 predicted gene 12967 /// predicted gene 4468 /// ribosomal protein L37 1434872_x_at chr15 A1 /// chr15 F1|15 /// chr4 D2.2 100040532 /// 100043481 /// 67281 13.5 7 3284 2700038G22Rik RIKEN cDNA 2700038G22 gene 1453745_at chr5 A3 67194 13.5 7 3285 Gm10079 /// Rps16 ribosomal protein S16 pseudogene /// ribosomal protein S16 1416404_s_at chr5 G1.3 /// chr7 A3 100039355 /// 20055 13.5 7 3286 LOC100047713 /// Mipep similar to Mipep protein /// mitochondrial intermediate peptidase 1428290_at chr14 D1 100047713 /// 70478 13.5 7 3287 Gm7669 /// Gm7901 /// Gm9347 /// Phgdh predicted gene 7669 /// 3-phosphoglycerate dehydrogenase pseudogene 1437621_x_at chr3 E1 /// chr7 F3|7 /// chr8 A1.1 /// chr8 C1 236539 /// 665516 /// 666036 /// 668771 13.5 7 3288 ----1458213_at ----13.5 7 3289 Cks2 CDC28 protein kinase regulatory subunit 2 1417458_s_at chr13 A5 66197 13.5 7 3290 Gm11425 /// Gm4957 /// Gm5962 /// Gm6285 /// Gm6336 /// Gm7117 /// LOC546695 predicted gene 11425 /// similar to ribosomal protein L12 1435725_x_at chr1 B /// chr10 D3 /// chr11 C /// chr16 B1 /// chr17 E1.3 241053 /// 269261 /// 546659 /// 546695 /// 622098 /// 622589 /// 630855 / 13.5 7 3291 Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein 1442058_s_at chr11 D 19183 13.5 7 3292 Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 1428297_at chr19 A 26412 13.5 7 3293 Rpl26 ribosomal protein L26 1436995_a_at chr11 B3 19941 13.5 7 3294 Uchl1 ubiquitin carboxy-terminal hydrolase L1 1448260_at chr5 C3.1|5 36.0 cM 22223 13.5 7 3295 Eny2 enhancer of yellow 2 homolog (Drosophila) 1429411_a_at chr15 B3.2 223527 13.5 7 3296 Thoc4 THO complex 4 1417724_at chr11 E2 21681 13.5 7 3297 LOC100047579 /// Tmem20 similar to transmembrane protein 20 /// transmembrane protein 20 1435452_at chr19 C3 100047579 /// 240660 13.5 7 3298 2900092E17Rik RIKEN cDNA 2900092E17 gene 1449617_at chr7 F4 67278 13.5 7 3299 9430038I01Rik RIKEN cDNA 9430038I01 gene 1431198_x_at chr7 F4 77252 13.5 7 3300 Hic2 hypermethylated in cancer 2 1437571_at chr16 B1 58180 13.5 7 3301 ----1442977_at ----13.5 7 3302 Rpl19 ribosomal protein L19 1416219_at chr11 D 19921 13.5 7 3303 Ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 1424085_at --17992 13.5 7 3304 Rpl35 ribosomal protein L35 1455950_x_at chr2 B 66489 13.5 7 3305 Aif1l allograft inflammatory factor 1-like 1424263_at chr2 B 108897 13.5 7 3306 Dync1i1 dynein cytoplasmic 1 intermediate chain 1 1416361_a_at chr6 A1|6 3.8 cM 13426 13.5 7 3307 2310030N02Rik RIKEN cDNA 2310030N02 gene 1429213_at chr4 A1 76947 13.5 7 3308 Rpl37 ribosomal protein L37 1453729_a_at chr15 A1 67281 13.5 7 3309 Gm13611 /// Gm4604 /// LOC100048508 /// Rpl36 predicted gene 13611 /// predicted gene 4604 /// similar to Rpl36 protein 1416520_x_at chr17 D /// chr2 B /// chr6 E1|6 100043718 /// 100048508 /// 54217 /// 622534 13.5 7 3310 Gm15451 /// Rpl10a ribosomal protein L10a pseudogene /// ribosomal protein L10A 1431177_a_at chr1 C2|1 /// chr17 A3.3 100043141 /// 19896 13.5 7 3311 Lypd6 LY6/PLAUR domain containing 6 1457843_at chr2 C1.1 320343 13.5 7 3312 Slc25a13 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 1449481_at chr6 A1 50799 13.5 7 3313 Cks2 CDC28 protein kinase regulatory subunit 2 1417457_at chr13 A5 66197 13.5 7 3314 Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1418005_at chr4 E1 67680 13.5 7 3315

PAGE 32

Rps17 ribosomal protein S17 1437510_x_at chr7 D3 20068 13.5 7 3316 ----1457416_at ----13.5 7 3317 Gm10119 /// Gm9000 /// Rps3a predicted gene 10119 /// predicted gene 9000 /// ribosomal protein S3A 1422475_a_at chr13 D2.1 /// chr14 E1 /// chr3 F1 100043780 /// 20091 /// 668144 13.5 7 3318 Ptges2 prostaglandin E synthase 2 1417591_at chr2 B 96979 13.5 7 3319 Tuba1a tubulin, alpha 1A 1418884_x_at chr15 F1|15 60.4 cM 22142 13.5 7 3320 Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d 1435112_a_at chr11 E2 71679 13.5 7 3321 Cgrrf1 cell growth regulator with ring finger domain 1 1453409_at chr14 C1 68755 13.5 7 3322 Actb actin, beta 1436722_a_at chr5 G2|5 80.0 cM 11461 13.5 7 3323 Fads1 fatty acid desaturase 1 1440444_at chr19 A 76267 13.5 7 3324 Dhfr dihydrofolate reductase 1419172_at chr13 C3|13 43.0 cM 13361 13.5 7 3325 Nme6 non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase) 1448574_at chr9 F2 54369 13.5 7 3326 Fam54a family with sequence similarity 54, member A 1432013_a_at chr10 A3 71804 13.5 7 3327 Mat2a methionine adenosyltransferase II, alpha 1438976_x_at chr6 C1 232087 13.5 7 3328 Bola2 bolA-like 2 (E. coli) 1434545_x_at chr7 F3 66162 13.5 7 3329 Trub2 TruB pseudouridine (psi) synthase homolog 2 (E. coli) 1451408_at chr2 B 227682 13.5 7 3330 Pa2g4 Proliferation-associated 2G4 1460265_at chr10 D3 18813 13.5 7 3331 Cdk4 /// LOC640611 cyclin-dependent kinase 4 /// similar to Cell division protein kinase 4 (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) 1422439_a_at chr10 D3 12567 /// 640611 13.5 7 3332 Sfrs7 splicing factor, arginine/serine-rich 7 1424883_s_at chr17 E3 225027 13.5 7 3333 2810422J05Rik /// Gm11808 /// Uba52 RIKEN cDNA 2810422J05 gene /// ubiquitin A-52 residue ribosomal protein fusion product 1 1452701_x_at chr4 A1 /// chr8 B3.3 /// chr8 B3.3|8 33.5 cM 22186 /// 666586 /// 75620 13.5 7 3334 3010003L21Rik RIKEN cDNA 3010003L21 gene 1415875_at chr6 G3 109163 13.5 7 3335 Wdr54 WD repeat domain 54 1422616_s_at chr6 D1 75659 13.5 7 3336 Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII 1430326_s_at chr11 B1.3 22272 13.5 7 3337 0610038B21Rik RIKEN cDNA 0610038B21 gene 1430930_at --70345 13.5 7 3338 Snrpe small nuclear ribonucleoprotein E 1451294_s_at chr1 E4 20643 13.5 7 3339 Rps4x ribosomal protein S4, X-linked 1416276_a_at chrX D|X 39.0 cM 20102 13.5 7 3340 Snrpn /// Snurf small nuclear ribonucleoprotein N /// SNRPN upstream reading frame 1435716_x_at chr7 C /// chr7 C|7 29.0 cM 20646 /// 84704 13.5 7 3341 Gm2423 /// Ywhaq Predicted gene 2423 /// Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 1454378_at chr12 A1.3 /// chr13 A1 100039786 /// 22630 13.5 7 3342 Gins2 GINS complex subunit 2 (Psf2 homolog) 1428713_s_at chr8 E1 272551 13.5 7 3343 Cnih4 cornichon homolog 4 (Drosophila) 1429763_at chr1 H4 98417 13.5 7 3344 Rps8 ribosomal protein S8 1455319_x_at chr4 D1 20116 13.5 7 3345 Ibsp integrin binding sialoprotein 1417485_at chr5 E5|5 56.0 cM 15891 13.5 7 3346 Gm9786 /// Oaz1 ornithine decarboxylase antizyme 1 pseudogene /// ornithine decarboxylase antizyme 1 1428868_a_at chr10 C1|10 43.0 cM /// chr17 A3.2|17 100041965 /// 18245 13.5 7 3347 2810417H13Rik RIKEN cDNA 2810417H13 gene 1419153_at chr9 C 68026 13.5 7 3348 Rps15a ribosomal protein S15A 1453467_s_at chr7 F2 267019 13.5 7 3349 Ndufa13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 1430713_s_at chr8 C1 67184 13.5 7 3350 Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) 1435054_at chr11 D 268465 13.5 7 3351 Rpl27 ribosomal protein L27 1453096_x_at chr11 A1 19942 13.5 7 3352 Gm9385 /// Rpl24 predicted gene 9385 /// ribosomal protein L24 1460201_a_at chr16 C1|16 31.5 cM /// chr9 F3 668829 /// 68193 13.5 7 3353 2310003L22Rik RIKEN cDNA 2310003L22 gene 1428745_a_at chr2 G3 69487 13.5 7 3354 Ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4 1448959_at chr13 D2.2 17993 13.5 7 3355 C230006B20 hypothetical LOC403344 1441157_at --403344 13.5 7 3356 Gm3756 /// Gm5620 /// Gm7172 /// LOC100044416 /// LOC100045728 /// Tuba1a /// predicted gene 3756 /// similar to tubulin, alpha 1 1416128_at chr12 B3 /// chr15 F1 /// chr15 F1|15 60.4 cM /// chr9 A4|9 100042266 /// 100044416 /// 100045728 /// 22142 /// 22143 /// 22146 /// 43 13.5 7 3357 Rplp1 ribosomal protein, large, P1 1416277_a_at chr9 B 56040 13.5 7 3358 Styxl1 serine/threonine/tyrosine interacting-like 1 1422299_a_at chr5 G2 76571 13.5 7 3359 Rpl35 ribosomal protein L35 1436840_x_at chr2 B 66489 13.5 7 3360 Chchd2 /// LOC100045688 coiled-coil-helix-coiled-coil-helix domain containing 2 /// similar to coiled-coil-helix-coiled-coil-helix domain containing 2 1428161_a_at chr5 G1.3 100045688 /// 14004 13.5 7 3361 2410003K15Rik RIKEN cDNA 2410003K15 gene 1428495_at --75593 13.5 7 3362 Tomm40l translocase of outer mitochondrial membrane 40 homolog-like (yeast) 1429382_at chr1 H3 641376 13.5 7 3363 Ccdc30 coiled-coil domain containing 30 1430190_at chr4 D2.1 73332 13.5 7 3364 Dnajc15 DnaJ (Hsp40) homolog, subfamily C, member 15 1416910_at chr14 D3 66148 13.5 7 3365 Plk4 polo-like kinase 4 (Drosophila) 1452115_a_at chr3 B 20873 13.5 7 3366 Rpl35 ribosomal protein L35 1434231_x_at chr2 B 66489 13.5 7 3367 Orc6l origin recognition complex, subunit 6-like (S. cerevisiae) 1417037_at chr8 C3 56452 13.5 7 3368 Gm10213 /// Gm10247 /// Gm10296 /// Gm15434 /// Ino80 /// LOC100046034 /// mC ribosomal protein L35a pseudogene 1417317_s_at chr1 H4 /// chr16 A1 /// chr16 B3 /// chr2 E5 /// chr5 B1 / 100040169 /// 100042363 /// 100042824 /// 100043106 /// 100046034 /// 1000 13.5 7 3369 Ins1 insulin I 1422447_at chr19 D2|19 49.0 cM 16333 13.5 7 3370 Wnt6 wingless-related MMTV integration site 6 1419708_at chr1 C3 22420 13.5 7 3371 Tpd52l1 tumor protein D52-like 1 1418412_at chr10 A4-B2 21987 13.5 7 3372 Rpl32 ribosomal protein L32 1435897_at chr6 E3|6 50.5 cM 19951 13.5 7 3373 Gm10051 /// Gm15435 /// Rpl28 predicted gene 10051 /// ribosomal protein L28 pseudogene /// ribosomal protein L28 1416074_a_at chr1 E4 /// chr5 G2 /// chr7 A1|7 4.0 cM 100039731 /// 100042670 /// 19943 13.5 7 3374 Gm11599 /// Gm12366 /// Gm14583 /// Gm16408 /// Gm5921 /// Gm6139 /// Gm8841 predicted gene 11599 /// 40S RIBOSOMAL PROTEIN S2 1422156_a_at chr1 C2 /// chr14 D3 /// chr4 A5 /// chr5 G1.3|5 /// chr8 D 100043752 /// 16898 /// 546164 /// 546298 /// 620248 /// 620559 /// 667592 13.5 7 3375 Ssr4 signal sequence receptor, delta 1448524_s_at chrX A7.3|X 29.5 cM 20832 13.5 7 3376 Pfdn1 prefoldin 1 1417026_at chr18 B2 67199 13.5 7 3377 Krt42 keratin 42 1439765_x_at chr11 D 68239 13.5 7 3378 Coq2 coenzyme Q2 homolog, prenyltransferase (yeast) 1452791_at chr5 E3 71883 13.5 7 3379 Gm11263 /// Gm13654 /// LOC100043734 /// LOC236932 /// Rps6 predicted gene 11263 /// predicted gene 13654 /// similar to 40S ribosomal protein S6 1455693_x_at chr14 D3 /// chr2 C3 /// chr4 C3 /// chrX D 100043734 /// 20104 /// 236932 /// 667739 /// 667922 13.5 7 3380 Rbm5 RNA binding motif protein 5 1456262_at chr9 F1 83486 13.5 7 3381 Gmnn geminin 1417506_at chr13 A3.1 57441 13.5 7 3382 Pop5 processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae) 1417972_s_at chr5 F 117109 13.5 7 3383 Rps2 ribosomal protein S2 1431766_x_at --16898 13.5 7 3384 Rpl18 ribosomal protein L18 1437005_a_at chr7 B4 19899 13.5 7 3385 Atp5k ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e 1434053_x_at chr5 F|5 56.0 cM 11958 13.5 7 3386 Rev3l REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) 1451960_a_at chr10 B1 19714 13.5 7 3387 Ndufa7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a) 1428360_x_at chr17 B1 66416 13.5 7 3388 Nisch nischarin 1433757_a_at chr14 B 64652 13.5 7 3389 ----1438104_at ----13.5 7 3390 Polr3k polymerase (RNA) III (DNA directed) polypeptide K 1422753_a_at chr2 H4 67005 13.5 7 3391 Dhrs13 dehydrogenase/reductase (SDR family) member 13 1452902_at chr11 B5 70451 13.5 7 3392 Apex1 apurinic/apyrimidinic endonuclease 1 1456079_x_at chr14 C3|14 18.5 cM 11792 13.5 7 3393 Guk1 guanylate kinase 1 1416395_at chr11 B1.3 14923 13.5 7 3394 Gm11353 /// Gm14289 /// Gm15501 /// Gm6998 /// LOC100042180 /// LOC100048094 predicted gene 11353 ribosomal protein S8 pseudogene /// similar to ribosomal protein S8 1436760_a_at chr10 B4 /// chr13 A3.1 /// chr2 H4 /// chr4 D1 /// chr7 E1 100039036 /// 100040298 /// 100042180 /// 100048094 /// 20116 /// 629732 / 13.5 7 3395 Rbx1 ring-box 1 1448387_at chr15 E1 56438 13.5 7 3396 Uxt ubiquitously expressed transcript 1418986_a_at chrX A2 22294 13.5 7 3397 Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 1446145_at chr4 D3 230861 13.5 7 3398 Phf20 PHD finger protein 20 1458017_at chr2 H1 228829 13.5 7 3399 Dut deoxyuridine triphosphatase 1419270_a_at chr2 F1|2 70.0 cM 110074 13.5 7 3400 ----1440314_at ----13.5 7 3401 Ndufaf2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 1452923_at chr13 D2.1 75597 13.5 7 3402 Mrpl20 mitochondrial ribosomal protein L20 1416093_a_at chr4 E2 66448 13.5 7 3403 Lsm3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1448536_at chr6 D2 67678 13.5 7 3404 5730422E09Rik RIKEN cDNA 5730422E09 gene 1444601_at chr5 G3 433966 13.5 7 3405 1110034G24Rik RIKEN cDNA 1110034G24 gene 1437617_x_at --73747 13.5 7 3406 Lck lymphocyte protein tyrosine kinase 1425396_a_at chr4 D2.2|4 59.0 cM 16818 13.5 7 3407 Rpl13 ribosomal protein L13 1455245_x_at chr8 E1 270106 13.5 7 3408 Ggn gametogenetin 1445278_at chr7 B1 243897 13.5 7 3409 Gm14303 /// Rps29 predicted gene 14303 /// ribosomal protein S29 1437413_x_at chr2 H3 20090 /// 629957 13.5 7 3410 Gpx4 glutathione peroxidase 4 1451695_a_at chr10 C1|10 43.0 cM 625249 13.5 7 3411 ----1455744_at ----13.5 7 3412 Tomm7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1428215_x_at chr5 A3 66169 13.5 7 3413 Fau /// Gm9843 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) /// predicted gene 9843 1417452_a_at chr16 C3.1|16 /// chr19 A|19 3.0 cM 100039316 /// 14109 13.5 7 3414 Rpl18a ribosomal protein L18A 1428152_a_at chr8 B3.3 76808 13.5 7 3415 Pcdh10 protocadherin 10 1421311_at chr3 C 18526 13.5 7 3416 Psmb1 proteasome (prosome, macropain) subunit, beta type 1 1448166_a_at chr17 A2|17 8.25 cM 19170 13.5 7 3417 Hint1 histidine triad nucleotide binding protein 1 1424018_at chr11 B1.3 15254 13.5 7 3418 Gm10164 /// Gm10223 /// Gm10268 /// Gm10362 /// Gm4329 /// Gm6133 /// Hk1 /// ribosomal protein L17 pseudogene /// ribosomal protein L17 pseudogene 1436822_x_at chr10 B4|10 30.0 cM /// chr12 A1.1|12 /// chr12 C2 /// chr1 100040745 /// 100040929 /// 100042067 /// 100042583 /// 100043273 /// 1000 13.5 7 3419 Ndufa7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a) 1450818_a_at chr17 B1 66416 13.5 7 3420 Cln3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) 1457789_at chr7 F3|7 60.4 cM 12752 13.5 7 3421 Eny2 enhancer of yellow 2 homolog (Drosophila) 1460392_a_at chr15 B3.2 223527 13.5 7 3422

PAGE 33

Gm13611 /// LOC100048508 /// Rpl36 predicted gene 13611 /// similar to Rpl36 protein /// ribosomal protein L36 1416519_at chr17 D /// chr2 B 100048508 /// 54217 /// 622534 13.5 7 3423 Phb2 prohibitin 2 1438938_x_at chr6 F2|6 60.22 cM 12034 13.5 7 3424 Ptgdr prostaglandin D receptor 1422171_at chr14 C1|14 13.5 cM 19214 13.5 7 3425 Gm10071 /// Gm12918 /// Gm15710 /// Rpl13 predicted gene 10071 /// predicted gene 15710 /// ribosomal protein L13 1450150_a_at chr3 D|5 /// chr4 A1 /// chr5 E2|5 /// chr8 E1 100039656 /// 100040416 /// 100040605 /// 270106 13.5 7 3426 LOC100045999 /// Ran similar to RAN, member RAS oncogene family /// RAN, member RAS oncogene family 1433569_x_at chr5 G1.3 100045999 /// 19384 13.5 7 3427 Cox4nb COX4 neighbor 1448677_at chr8 E1|8 64.0 cM 18117 13.5 7 3428 Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1457528_at chr14 A2 218756 13.5 7 3429 Cox7a2 cytochrome c oxidase, subunit VIIa 2 1416970_a_at chr9 E1|9 42.0 cM 12866 13.5 7 3430 Atp5k ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e 1422525_at chr5 F|5 56.0 cM 11958 13.5 7 3431 Trnau1ap tRNA selenocysteine 1 associated protein 1 1428747_at chr4 D3|4 71787 13.5 7 3432 Trub2 TruB pseudouridine (psi) synthase homolog 2 (E. coli) 1424611_x_at chr2 B 227682 13.5 7 3433 Gm11263 /// Gm13654 /// Gm14138 /// Gm6476 /// Gm8779 /// LOC100043734 /// LO predicted gene 11263 /// 40S ribosomal protein S6 (Phosphoprotein NP33) 1454620_x_at chr13 A5|13 /// chr14 D3 /// chr17 E2 /// chr2 C3 /// chr2 100043734 /// 20104 /// 236932 /// 545640 /// 624159 /// 639593 /// 667717 13.5 7 3434 Rpl34 ribosomal protein L34 1438655_a_at chr3 G3 68436 13.5 7 3435 Dnajc24 DnaJ (Hsp40) homolog, subfamily C, member 24 1451389_at chr2 E3 99349 13.5 7 3436 1500004F05Rik RIKEN cDNA 1500004F05 gene 1456899_at chr8 A4 69765 13.5 7 3437 Nme4 non-metastatic cells 4, protein expressed in 1416798_a_at chr17 B1 56520 13.5 7 3438 Batf3 basic leucine zipper transcription factor, ATF-like 3 1453076_at chr1 H6 381319 13.5 7 3439 Actb actin, beta 1419734_at chr5 G2|5 80.0 cM 11461 13.5 7 3440 Rpl27a ribosomal protein L27A 1426661_at chr7 E2-F1|7 51.55 cM 26451 13.5 7 3441 Rpl11 ribosomal protein L11 1417615_a_at chr4 D3 67025 13.5 7 3442 ----1447449_at ----13.5 7 3443 Lsm4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1448622_at chr8 B3.3 50783 13.5 7 3444 Gm13654 /// Rps6 predicted gene 13654 /// ribosomal protein S6 1434377_x_at chr2 C3 /// chr4 C3 20104 /// 667739 13.5 7 3445 Gm10335 /// Gm3940 /// Gm5384 /// Gm7413 /// Gm8158 /// LOC100042058 /// Rpl2 predicted gene 10335 /// similar to ribosomal protein L23a /// ribosomal protein L23a 1437975_a_at chr1 C1.1|1 /// chr10 A2 /// chr10 B4 /// chr10 C1 /// chr1 100039571 /// 100042058 /// 100042634 /// 268449 /// 385336 /// 664936 /// 13.5 7 3446 Rps27 ribosomal protein S27 1415716_a_at chr3 F1 57294 13.5 8 3447 Gm10164 /// Gm10223 /// Gm10294 /// LOC100041933 /// LOC100046300 /// Rpl17 ribosomal protein L17 pseudogene /// ribosomal protein L17 pseudogene 1423855_x_at chr12 C2 /// chr18 E3 /// chr5 A3 /// chr7 D1 100040745 /// 100041933 /// 100042067 /// 100042880 /// 100046300 /// 3191 13.5 8 3448 ----1457358_at ----13.5 8 3449 Tpt1 tumor protein, translationally-controlled 1 1416642_a_at chr14 D3 22070 13.5 8 3450 Gm9840 /// Rbx1 predicted gene 9840 /// ring-box 1 1438623_x_at chr15 E1 /// chr17 B1|17 100043674 /// 56438 13.5 8 3451 Cklf chemokine-like factor 1451832_at chr8 D3 75458 13.5 8 3452 2810422J05Rik /// Gm11808 /// Uba52 RIKEN cDNA 2810422J05 gene /// ubiquitin A-52 residue ribosomal protein fusion product 1 1416624_a_at chr4 A1 /// chr8 B3.3 /// chr8 B3.3|8 33.5 cM 22186 /// 666586 /// 75620 13.5 8 3453 Rpp30 Ribonuclease P/MRP 30 subunit (human) 1447970_at chr19 C2 54364 13.5 8 3454 Polr3k polymerase (RNA) III (DNA directed) polypeptide K 1439266_a_at chr2 H4 67005 13.5 8 3455 C78704 expressed sequence C78704 1458862_at --97868 13.5 8 3456 Rock1 Rho-associated coiled-coil containing protein kinase 1 1441162_at chr18 A2 19877 13.5 8 3457 ----1441722_at ----13.5 8 3458 Lama1 laminin, alpha 1 1418153_at chr17 E1.1|17 38.0 cM 16772 13.5 8 3459 Snhg7 Small nucleolar RNA host gene (non-protein coding) 7 1447484_x_at --72091 13.5 8 3460 ----1457529_x_at ----13.5 8 3461 Rps11 ribosomal protein S11 1424000_a_at chr7 B4 27207 13.5 8 3462 4930474A20Rik RIKEN cDNA 4930474A20 gene 1433370_at --74940 13.5 8 3463 Gm10027 /// Gm10260 /// Rps18 ribosomal protein S18 pseudogene /// predicted gene 10260 /// ribosomal protein S18 1435712_a_at chr13 D1 /// chr17 B1|17 18.42 cM /// chr8 D3 100039740 /// 100042791 /// 20084 13.5 8 3464 Srrm1 serine/arginine repetitive matrix 1 1450045_at chr4 D3 51796 13.5 8 3465 Aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) 1458873_at chr1 F 12316 13.5 8 3466 Kcne3 potassium voltage-gated channel, Isk-related subfamily, gene 3 1418499_a_at chr7 F1 57442 13.5 8 3467 Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 1455168_a_at chr11 B1.2 14694 13.5 8 3468 ----1458650_at ----13.5 8 3469 Nktr natural killer tumor recognition sequence 1437660_at chr9 F4|9 71.0 cM 18087 13.5 8 3470 A630007B06Rik RIKEN cDNA A630007B06 gene 1444371_at chr19 D2 213993 13.5 8 3471 Ctr9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1442240_at chr7 F1|7 54.0 cM 22083 13.5 8 3472 Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 1455987_at chr6 D1 53421 13.5 8 3473 Gm10117 /// Gm7206 /// Gm9822 /// Rpl9 ribosomal protein L9 pseudogene /// ribosomal protein L9 pseudogene /// ribosomal protein L9 1416420_a_at chr14 C1 /// chr19 C1 /// chr2 C2 /// chr5 C3.1 100040021 /// 100042823 /// 20005 /// 637379 13.5 8 3474 Pdia6 protein disulfide isomerase associated 6 1430983_at chr12 A1.1 71853 13.5 8 3475 Dab1 disabled homolog 1 (Drosophila) 1421100_a_at chr4 C6|4 52.7 cM 13131 13.5 8 3476 ----1445837_at ----13.5 8 3477 Cenpa centromere protein A 1450842_a_at chr5 B1|5 18.0 cM 12615 13.5 8 3478 ----1443526_at ----13.5 8 3479 Tmtc3 Transmembrane and tetratricopeptide repeat containing 3 1457294_at chr10 D1 237500 13.5 8 3480 ----1457851_at ----13.5 8 3481 Clasp1 CLIP associating protein 1 1459233_at chr1 E2 76707 13.5 8 3482 Dnajc17 /// Gm6257 DnaJ (Hsp40) homolog, subfamily C, member 17 /// DnaJ (Hsp40) homolog, subfamily C, member 17 pseudogene 1446928_at chr2 E5|2 36.0 cM /// chr9 C 621763 /// 69408 13.5 8 3483 Gm10027 /// Gm10260 /// Rps18 ribosomal protein S18 pseudogene /// predicted gene 10260 1448739_x_at chr13 D1 /// chr17 B1|17 18.42 cM /// chr8 D3 100039740 /// 100042791 /// 20084 13.5 8 3484 2610036L11Rik RIKEN cDNA 2610036L11 gene 1453053_at chr10 A4 66311 13.5 8 3485 Rbx1 ring-box 1 1416577_a_at chr15 E1 56438 13.5 8 3486 Immp1l IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1451217_a_at chr2 E3 66541 13.5 8 3487 Mrpl11 mitochondrial ribosomal protein L11 1417918_at chr19 A 66419 13.5 8 3488 ----1446029_at ----13.5 8 3489 Mrpl12 mitochondrial ribosomal protein L12 1452048_at chr11 E2 56282 13.5 8 3490 Slc38a2 solute carrier family 38, member 2 1429593_at chr15 F1 67760 13.5 8 3491 1110050K14Rik RIKEN cDNA 1110050K14 gene 1430012_at --68790 13.5 8 3492 Srrm2 serine/arginine repetitive matrix 2 1437638_at chr17 A3.3 75956 13.5 8 3493 Hba-a1 /// Hba-a2 hemoglobin alpha, adult chain 1 /// hemoglobin alpha, adult chain 2 1452757_s_at chr11 A4|11 16.0 cM /// chr11|11 16.0 cM 110257 /// 15122 13.5 8 3494 Ubxn2b UBX domain protein 2B 1430816_at chr4 A1 68053 13.5 8 3495 LOC552876 hypothetical LOC552876 1442041_at --552876 13.5 8 3496 Ddx50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1453852_at chr10 B4 94213 13.5 8 3497 ----1442519_at ----13.5 8 3498 1700085D22Rik RIKEN cDNA 1700085D22 gene 1453348_at --73512 13.5 8 3499 Mesdc1 mesoderm development candidate 1 1416398_at chr7 D3 80889 13.5 8 3500 Rplp0 ribosomal protein, large, P0 1419441_at chr5 F 11837 13.5 8 3501 Tmem168 transmembrane protein 168 1432311_at chr6 A2 101118 13.5 8 3502 Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) 1436898_at chr4 D2.2|4 57.6 cM 71514 13.5 8 3503 Foxk2 forkhead box K2 1442933_at chr11 E2 68837 13.5 8 3504 AI314760 expressed sequence AI314760 1437923_at --106885 13.5 8 3505 Rps14 ribosomal protein S14 1436586_x_at chr18 E1|18 30.0 cM 20044 13.5 8 3506 Hist1h2ad histone cluster 1, H2ad 1438009_at --319165 13.5 8 3507 ----1432828_at ----13.5 8 3508 Cltc clathrin, heavy polypeptide (Hc) 1439094_at chr11 C 67300 13.5 8 3509 Rpl9 Ribosomal protein L9 1443843_x_at chr5 C3.1 20005 13.5 8 3510 Ccdc83 coiled-coil domain containing 83 1453923_at chr7 E1 75338 13.5 8 3511 Fabp3 fatty acid binding protein 3, muscle and heart 1444844_at chr4 D2.2|4 61.0 cM 14077 13.5 8 3512 ----1443354_at ----13.5 8 3513 Rpl41 ribosomal protein L41 1422623_x_at chr10 D3 67945 13.5 8 3514 Wnt5a wingless-related MMTV integration site 5A 1456976_at chr14 A3|14 7.8 cM 22418 13.5 8 3515 Gm5805 /// Rps14 predicted gene 5805 /// ribosomal protein S14 1437706_x_at chr15 E1 /// chr18 E1|18 30.0 cM 20044 /// 545121 13.5 8 3516 ----1426061_x_at ----13.5 8 3517 Acvr1c activin A receptor, type IC 1428032_at chr2 C1.1 269275 13.5 8 3518 Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 1446376_at chr11 C 72508 13.5 8 3519 6230409E13Rik RIKEN cDNA 6230409E13 gene 1440611_at chr4 A3 76132 13.5 8 3520 ----1459350_at ----13.5 8 3521 2310001K24Rik RIKEN cDNA 2310001K24 gene 1430525_at chr2 H3 69517 13.5 8 3522 Kdm5b Lysine (K)-specific demethylase 5B 1442278_at chr1 E4|1 72.0 cM 75605 13.5 8 3523 Pde10a phosphodiesterase 10A 1432490_a_at chr17 A1 23984 13.5 8 3524 ----1440685_at ----13.5 8 3525 Fubp1 far upstream element (FUSE) binding protein 1 1437543_at chr3 H3|3 70.5 cM 51886 13.5 8 3526 Cldn7 claudin 7 1448393_at chr11 B4 53624 13.5 8 3527 Ube2b ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae) 1439477_at chr11 B1.3 22210 13.5 8 3528 Dtl denticleless homolog (Drosophila) 1456652_at chr1 H6 76843 13.5 8 3529

PAGE 34

Tmsb10 thymosin, beta 10 1417219_s_at chr6 C1 19240 13.5 8 3530 Zcchc11 zinc finger, CCHC domain containing 11 1439631_at chr4 C7 230594 13.5 8 3531 Palld palladin, cytoskeletal associated protein 1440635_at chr8 B3.3 72333 13.5 8 3532 Tmem160 transmembrane protein 160 1460424_at chr7 A2 69094 13.5 8 3533 ----1432676_at ----13.5 8 3534 ----1439823_at ----13.5 8 3535 Kif13a kinesin family member 13A 1442252_at chr13 B1 16553 13.5 8 3536 Hmga2 high mobility group AT-hook 2 1422851_at chr10 D2|10 67.5 cM 15364 13.5 8 3537 Pus3 pseudouridine synthase 3 1429222_at chr9 A5.3 67049 13.5 8 3538 Nsun4 NOL1/NOP2/Sun domain family, member 4 1445570_at chr4 D1 72181 13.5 8 3539 ----1444231_at ----13.5 8 3540 Mast4 microtubule associated serine/threonine kinase family member 4 1445866_at chr13 D1 328329 13.5 8 3541 ----1457383_at ----13.5 8 3542 Zfp826 zinc finger protein 826 1428748_at chr19 D3 414758 13.5 8 3543 Meis1 Meis homeobox 1 1443260_at chr11 A3.1|11 11.0 cM 17268 13.5 8 3544 1810029B16Rik RIKEN cDNA 1810029B16 gene 1431117_x_at chr8 B3.3 66282 13.5 8 3545 A430108E01Rik RIKEN cDNA A430108E01 gene 1435267_at chr8 A1.3 384382 13.5 8 3546 March7 membrane-associated ring finger (C3HC4) 7 1440966_at chr2 C3 57438 13.5 8 3547 ----1447706_at ----13.5 8 3548 ----1444705_at ----13.5 8 3549 Bcorl1 BCL6 co-repressor-like 1 1454172_at chrX A4 320376 13.5 8 3550 Ube2d2 ubiquitin-conjugating enzyme E2D 2 1445885_at chr18 B2 56550 13.5 8 3551 LOC435565 interferon-inducible GTPase-like 1425722_at chr18 D3 435565 13.5 8 3552 LOC433197 hypothetical gene supported by AK028463 1446398_at chr18 E2 433197 13.5 8 3553 Brd8 bromodomain containing 8 1429526_at chr18 B1 78656 13.5 8 3554 Rbm39 RNA binding motif protein 39 1438420_at chr2 H1 170791 13.5 8 3555 ----1456991_at ----13.5 8 3556 Ick intestinal cell kinase 1454243_at chr9 E1 56542 13.5 8 3557 Rpl13a ribosomal protein L13A 1455001_x_at chr7 B4|7 69.0 cM 22121 13.5 8 3558 5730408K05Rik RIKEN cDNA 5730408K05 gene 1429207_at --67531 13.5 8 3559 ----1439191_at ----13.5 8 3560 Rsrc2 arginine/serine-rich coiled-coil 2 1442083_at chr5 F 208606 13.5 8 3561 Eps15 epidermal growth factor receptor pathway substrate 15 1430152_at chr4 C7 13858 13.5 8 3562 5830462P14Rik RIKEN cDNA 5830462P14 gene 1432997_at --76098 13.5 8 3563 Dusp9 dual specificity phosphatase 9 1433844_a_at chrX B 75590 13.5 8 3564 AL023051 expressed sequence AL023051 1444675_at --100782 13.5 8 3565 Trappc6a trafficking protein particle complex 6A 1460054_at chr7 A3 67091 13.5 8 3566 Dppa5a developmental pluripotency associated 5A 1416552_at chr9 E1 434423 13.5 8 3567 Wfdc2 WAP four-disulfide core domain 2 1424351_at chr2 H3 67701 13.5 8 3568 Rbm39 RNA binding motif protein 39 1439316_at chr2 H1 170791 13.5 8 3569 Rint1 RAD50 interactor 1 1431147_at chr5 A3 72772 13.5 8 3570 C230076A16Rik RIKEN cDNA C230076A16 gene 1441196_at --320496 13.5 8 3571 2810410L24Rik RIKEN cDNA 2810410L24 gene 1438972_x_at chr11 E2 100042332 13.5 8 3572 Cwf19l2 CWF19-like 2, cell cycle control (S. pombe) 1453688_at chr9 A1 244672 13.5 8 3573 Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 1441417_at chr9 A4|9 20.0 cM 16430 13.5 8 3574 9930017N22Rik RIKEN cDNA 9930017N22 gene 1456758_at --320403 13.5 8 3575 Prcp prolylcarboxypeptidase (angiotensinase C) 1431361_at chr7 E2 72461 13.5 8 3576 ----1444598_at ----13.5 8 3577 Hmga2 high mobility group AT-hook 2 1450781_at chr10 D2|10 67.5 cM 15364 13.5 8 3578 C80998 expressed sequence C80998 1456050_at --97819 13.5 8 3579 Sec61g SEC61, gamma subunit 1423090_x_at chr11 A2 20335 13.5 8 3580 H3f3b H3 histone, family 3B 1430357_at chr11 E2 15081 13.5 8 3581 AI131651 expressed sequence AI131651 1440736_at --98858 13.5 8 3582 ----1442262_at ----13.5 8 3583 ----1444557_at ----13.5 8 3584 Marcks Myristoylated alanine rich protein kinase C substrate 1430311_at chr10 B1|10 22.0 cM 17118 13.5 8 3585 ----1460126_at ----13.5 8 3586 1810027O10Rik RIKEN cDNA 1810027O10 gene 1430985_at chr11 B4 69186 13.5 8 3587 6820431F20Rik RIKEN cDNA 6820431F20 gene 1437717_x_at chr8 A1.3 381598 13.5 8 3588 LOC552906 hypothetical LOC552906 1438127_at --552906 13.5 8 3589 ----1458766_at ----13.5 8 3590 Lrch3 Leucine-rich repeats and calponin homology (CH) domain containing 3 1443199_at chr16 B3 70144 13.5 8 3591 BC002199 cDNA sequence BC002199 1446235_at chr3 G2 211556 13.5 8 3592 Hba-a1 /// Hba-a2 hemoglobin alpha, adult chain 1 /// hemoglobin alpha, adult chain 2 1428361_x_at chr11 A4|11 16.0 cM /// chr11|11 16.0 cM 110257 /// 15122 13.5 8 3593 Gm9844 /// Tmsb10 predicted gene 9844 /// thymosin, beta 10 1436902_x_at chr6 C1 /// chr7 A3 100043712 /// 19240 13.5 8 3594 ----1439672_at ----13.5 8 3595 D5Wsu178e DNA segment, Chr 5, Wayne State University 178, expressed 1442069_at chr5 B1|5 18.0 cM 28042 13.5 8 3596 Cep192 Centrosomal protein 192 1440081_at chr18 E1 70799 13.5 8 3597 ----1430183_at ----13.5 8 3598 Plekha2 pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2 1436177_at chr8 A2 83436 13.5 8 3599 ----1441397_at ----13.5 8 3600 Myeov2 myeloma overexpressed 2 1433516_a_at chr1 D 66915 13.5 8 3601 Snhg3 small nucleolar RNA host gene (non-protein coding) 3 1433789_at chr4 D2.3 399101 13.5 8 3602 2810055G20Rik RIKEN cDNA 2810055G20 gene 1445363_at chr16 C3.1 77994 13.5 8 3603 5430434G16Rik RIKEN cDNA 5430434G16 gene 1441976_at --71385 13.5 8 3604 ----1457073_at ----13.5 8 3605 2810046L04Rik RIKEN cDNA 2810046L04 gene 1429821_at chr3 C 212127 13.5 8 3606 ----1447062_at ----13.5 8 3607 ----1447379_at ----13.5 8 3608 Gm5871 /// Smndc1 predicted gene 5871 /// survival motor neuron domain containing 1 1443396_at chr19 D2 /// chr5 F 545792 /// 76479 13.5 8 3609 ----1443512_at ----13.5 8 3610 ----1445116_at ----13.5 8 3611 Hbb-b1 /// Hbb-b2 hemoglobin, beta adult major chain /// hemoglobin, beta adult minor chain 1417184_s_at chr7 E3|7 50.0 cM 15129 /// 15130 13.5 8 3612 Tmem186 transmembrane protein 186 1439726_at chr16 A1 66690 13.5 8 3613 ----1458979_at ----13.5 8 3614 C77648 expressed sequence C77648 1444445_at --97695 13.5 8 3615 ----1451930_at ----13.5 8 3616 2700094K13Rik RIKEN cDNA 2700094K13 gene 1436349_at chr2 D 72657 13.5 8 3617 ----1444762_at ----13.5 8 3618 D10Ertd709e DNA segment, Chr 10, ERATO Doi 709, expressed 1457539_at chr10 60.0 cM 52701 13.5 8 3619 Phip pleckstrin homology domain interacting protein 1438535_at chr9 E3.1 83946 13.5 8 3620 ----1441869_x_at ----13.5 8 3621 ----1442442_at ----13.5 8 3622 AI428301 expressed sequence AI428301 1457150_at --106201 13.5 8 3623 Ube2t ubiquitin-conjugating enzyme E2T (putative) 1422462_at chr1 E4 67196 13.5 8 3624 ----1443546_at ----13.5 8 3625 Rpa3 replication protein A3 1448938_at chr6 A1 68240 13.5 8 3626 Car10 carbonic anhydrase 10 1431288_at chr11 C 72605 13.5 8 3627 2810427A07Rik RIKEN cDNA 2810427A07 gene 1437576_at --72767 13.5 8 3628 Rtn4 reticulon 4 1439650_at chr11 A3.3 68585 13.5 8 3629 ----1446384_at ----13.5 8 3630 Usp8 ubiquitin specific peptidase 8 1446807_at chr2 F1 84092 13.5 8 3631 AA415038 expressed sequence AA415038 1457111_at --103570 13.5 8 3632 2410022L05Rik RIKEN cDNA 2410022L05 gene 1420113_s_at chr8 A1.1 66423 13.5 8 3633 Wnt7a wingless-related MMTV integration site 7A 1423367_at chr6 D1|6 39.5 cM 22421 13.5 8 3634 Gm9844 /// LOC100048142 /// Tmsb10 predicted gene 9844 /// similar to thymosin, beta 10 /// thymosin, beta 10 1437185_s_at chr6 C1 /// chr7 A3 100043712 /// 100048142 /// 19240 13.5 8 3635 ----1439233_at ----13.5 8 3636

PAGE 35

----1441172_at ----13.5 8 3637 Fam168a Family with sequence similarity 168, member A 1444119_at chr7 E3 319604 13.5 8 3638 Prei4 preimplantation protein 4 1429639_at chr2 F3|2 74182 13.5 8 3639 Myeov2 myeloma overexpressed 2 1434823_x_at chr1 D 66915 13.5 8 3640 Rpl41 ribosomal protein L41 1455578_x_at chr10 D3 67945 13.5 8 3641 Robo2 roundabout homolog 2 (Drosophila) 1458229_at chr16 C3.1 268902 13.5 8 3642 Rps3 ribosomal protein S3 1435151_a_at chr7 F1|7 49.6 cM 27050 13.5 8 3643 ----1437162_at ----13.5 8 3644 Gas5 growth arrest specific 5 1455904_at chr1 H2.1 14455 13.5 8 3645 Zmym5 zinc finger, MYM-type 5 1445543_at chr14 C3 219105 13.5 8 3646 Tagln3 transgelin 3 1450683_at chr16 B5 56370 13.5 8 3647 Tomm5 translocase of outer mitochondrial membrane 5 homolog (yeast) 1415733_a_at chr4 B1 68512 13.5 8 3648 Rprm reprimo, TP53 dependent G2 arrest mediator candidate 1422552_at chr2 C1 67874 13.5 8 3649 Twsg1 twisted gastrulation homolog 1 (Drosophila) 1426073_at chr17 E1.1|17 38.0 cM 65960 13.5 8 3650 2900010M23Rik RIKEN cDNA 2900010M23 gene 1436810_x_at chr17 B1 67267 13.5 8 3651 Mta3 metastasis associated 3 1443350_at chr17 E4 116871 13.5 8 3652 Rps25 ribosomal protein S25 1451068_s_at chr9 A5.2 75617 13.5 8 3653 D4Ertd117e DNA segment, Chr 4, ERATO Doi 117, expressed 1419947_at chr4 76.5 cM 52164 13.5 8 3654 Arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 1456917_at chr1 A2 211673 13.5 8 3655 A230070E04Rik RIKEN cDNA A230070E04 gene 1443133_at chr14 D1 654794 13.5 8 3656 Tnfrsf19 tumor necrosis factor receptor superfamily, member 19 1425212_a_at chr14 D1 29820 13.5 8 3657 6720475J19Rik RIKEN cDNA 6720475J19 gene 1423072_at chr19 A 68157 13.5 8 3658 Akr1b7 aldo-keto reductase family 1, member B7 1423556_at chr6 B1|6 14.0 cM 11997 13.5 8 3659 Rplp2 ribosomal protein, large P2 1415879_a_at chr7 F5 67186 13.5 8 3660 Mrpl54 mitochondrial ribosomal protein L54 1448699_at chr10 C1|10 43.0 cM 66047 13.5 8 3661 Tyms /// Tyms-ps thymidylate synthase /// thymidylate synthase, pseudogene 1424991_s_at chr10 C1 /// chr5 B1|5 18.2 cM 22171 /// 22172 13.5 8 3662 Gm13020 /// Gm7379 /// Rpl38 ribosomal protein L38 pseudogene /// ribosomal protein L38 pseudogene /// ribosomal protein L38 1433472_x_at chr11 G1 /// chr4 D3 /// chr6 G2 625646 /// 664868 /// 67671 13.5 8 3663 Nme2 non-metastatic cells 2, protein (NM23B) expressed in 1448808_a_at chr11 C 18103 13.5 8 3664 Anapc11 Anaphase promoting complex subunit 11 1447897_x_at chr11 E2 66156 13.5 8 3665 Arhgap5 Rho GTPase activating protein 5 1457410_at chr12 C1|12 25.75 cM 11855 13.5 8 3666 Gm13654 /// Rps6 predicted gene 13654 /// ribosomal protein S6 1416141_a_at chr2 C3 /// chr4 C3 20104 /// 667739 13.5 8 3667 ----1457348_at ----13.5 8 3668 ----1443436_at ----13.5 8 3669 ----1442692_at ----13.5 8 3670 Rps10 ribosomal protein S10 1456497_x_at chr17 B1 67097 13.5 8 3671 Egf epidermal growth factor 1418093_a_at chr3 G3|3 65.2 cM 13645 13.5 8 3672 2810046L04Rik RIKEN cDNA 2810046L04 gene 1427397_at chr3 C 212127 13.5 8 3673 Ppil1 peptidylprolyl isomerase (cyclophilin)-like 1 1428892_at chr17 A3.3 68816 13.5 8 3674 Gm3362 /// Rpl23a predicted gene 3362 /// ribosomal protein L23a 1426659_a_at chr11 B5 /// chr15 B3.1|15 100041478 /// 268449 13.5 8 3675 ----1445662_x_at ----13.5 8 3676 LOC497255 hypothetical LOC497255 1459678_at --497255 13.5 8 3677 Gm14303 /// Rps29 predicted gene 14303 /// ribosomal protein S29 1415833_x_at chr2 H3 20090 /// 629957 13.5 8 3678 Rps7 ribosomal protein S7 1419364_a_at chr12 C1 20115 13.5 8 3679 Tomm20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1423081_a_at chr8 E2 67952 13.5 8 3680 ----1436145_at ----13.5 8 3681 Eif3h eukaryotic translation initiation factor 3, subunit H 1415962_at chr15 D1 68135 13.5 8 3682 Tomm7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1428216_s_at chr5 A3 66169 13.5 8 3683 Gapvd1 GTPase activating protein and VPS9 domains 1 1444066_at chr2 B 66691 13.5 8 3684 Rps10 ribosomal protein S10 1416719_a_at chr17 B1 67097 13.5 8 3685 4930456A14Rik RIKEN cDNA 4930456A14 gene 1432968_at --74676 13.5 8 3686 Id2 inhibitor of DNA binding 2 1453596_at chr12 B|12 7.0 cM 15902 13.5 8 3687 Hint1 histidine triad nucleotide binding protein 1 1424017_a_at chr11 B1.3 15254 13.5 8 3688 Cxcl14 chemokine (C-X-C motif) ligand 14 1418456_a_at chr13 B1 57266 13.5 8 3689 Evl /// LOC100047333 Ena-vasodilator stimulated phosphoprotein /// similar to Ena-VASP-like 1440885_at chr12 F2 100047333 /// 14026 13.5 8 3690 Alg14 asparagine-linked glycosylation 14 homolog (yeast) 1419116_at chr3 G1 66789 13.5 8 3691 Rps21 ribosomal protein S21 1433721_x_at chr2 H4 66481 13.5 8 3692 Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 1443990_at chr3 F1|3 48.0 cM 18211 13.5 8 3693 Tubb3 tubulin, beta 3 1415978_at chr8 E1 22152 13.5 8 3694 Slfn9 schlafen 9 1458803_at chr11 C 237886 13.5 8 3695 Foxf1a forkhead box F1a 1434939_at chr8 67.0 cM 15227 13.5 8 3696 Rpl13a ribosomal protein L13A 1417608_a_at chr7 B4|7 69.0 cM 22121 13.5 8 3697 Wwox WW domain-containing oxidoreductase 1431960_at --80707 13.5 8 3698 Rpl13a ribosomal protein L13A 1455485_x_at chr7 B4|7 69.0 cM 22121 13.5 8 3699 ----1438753_at ----13.5 8 3700 ----1443056_at ----13.5 8 3701 Bri3 brain protein I3 1416924_at chr5 G2 55950 13.5 8 3702 Lypd6 LY6/PLAUR domain containing 6 1456138_at chr2 C1.1 320343 13.5 8 3703 2810408I11Rik RIKEN cDNA 2810408I11 gene 1437549_at --69941 13.5 8 3704 1110008J03Rik RIKEN cDNA 1110008J03 gene 1419333_at chr5 F 100764 13.5 8 3705 Gm9999 predicted gene 9999 1439149_s_at chr7 B4|7 629141 13.5 8 3706 Zmym4 zinc finger, MYM-type 4 1438460_at chr4 D2.2 67785 13.5 8 3707 Alkbh3 alkB, alkylation repair homolog 3 (E. coli) 1444184_at chr2 E1 69113 13.5 8 3708 Psma7 proteasome (prosome, macropain) subunit, alpha type 7 1423567_a_at chr2 H4 26444 13.5 8 3709 Nubp1 nucleotide binding protein 1 1418906_at chr16 A1|16 3.4 cM 26425 13.5 8 3710 ----1446953_at ----13.5 8 3711 Thyn1 thymocyte nuclear protein 1 1438769_a_at chr9 A4 77862 13.5 8 3712 Gm7969 Predicted gene 7969 1455240_x_at chr13 B3|13 666185 13.5 8 3713 Arrdc3 Arrestin domain containing 3 1459253_at chr13 C3 105171 13.5 8 3714 Usp14 ubiquitin specific peptidase 14 1439201_at chr18 A1|18 2.0 cM 59025 13.5 8 3715 Nacc1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 1420968_at chr8 C3|8 35.0 cM 66830 13.5 8 3716 Ccdc79 coiled-coil domain containing 79 1442013_at chr8 D3 320022 13.5 8 3717 Fam115a family with sequence similarity 115, member A 1430436_at chr6 B2|6 77574 13.5 8 3718 Opalin oligodendrocytic myelin paranodal and inner loop protein 1435854_at chr19 C3 226115 13.5 8 3719 ----1441248_at ----13.5 8 3720 LOC100046223 /// Rps15 similar to insulinoma protein (rig) /// ribosomal protein S15 1416088_a_at chr10 C1 100046223 /// 20054 13.5 8 3721 Tia1 cytotoxic granule-associated RNA binding protein 1 1431708_a_at chr6 D2 21841 13.5 8 3722 Abce1 ATP-binding cassette, sub-family E (OABP), member 1 1442071_at chr8 C 24015 13.5 8 3723 ----1458391_at ----13.5 8 3724 Rps15 ribosomal protein S15 1416089_at chr10 C1 20054 13.5 8 3725 Eef1a1 eukaryotic translation elongation factor 1 alpha 1 1424635_at chr9 E1 13627 13.5 8 3726 Rps10 ribosomal protein S10 1438723_a_at chr17 B1 67097 13.5 8 3727 4930588G05Rik RIKEN cDNA 4930588G05 gene 1430175_at --78817 13.5 8 3728 Xist inactive X specific transcripts 1436936_s_at chrX D 213742 13.5 8 3729 Mrpl11 mitochondrial ribosomal protein L11 1437131_x_at chr19 A 66419 13.5 8 3730 ----1446234_at ----13.5 8 3731 Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 1446965_at chr9 B 69632 13.5 8 3732 Cenph centromere protein H 1422016_a_at chr13 D1|13 51.0 cM 26886 13.5 8 3733 Gm10079 /// LOC100047501 /// Rps16 ribosomal protein S16 pseudogene /// ribosomal protein S16 1437196_x_at chr5 G1.3 /// chr7 A3 100039355 /// 100047501 /// 20055 13.5 8 3734 Rpl13a /// Zfp526 ribosomal protein L13A /// zinc finger protein 526 1435873_a_at chr7 A3 /// chr7 B4|7 69.0 cM 210172 /// 22121 13.5 8 3735 ----1441037_at ----13.5 8 3736 2610318N02Rik RIKEN cDNA 2610318N02 gene 1429268_at chr16 A3 70458 13.5 8 3737 ----1445411_at ----13.5 8 3738 Commd2 COMM domain containing 2 1433594_at chr3 D|3 30.0 cM 52245 13.5 8 3739 Slc25a19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 1437459_x_at chr11 E2 67283 13.5 8 3740 Kdm2a Lysine (K)-specific demethylase 2A 1438890_at chr19 A 225876 13.5 8 3741 Erbb2ip Erbb2 interacting protein 1439079_a_at chr13 D1 59079 13.5 8 3742 Ccdc142 /// Mrpl53 coiled-coil domain containing 142 /// mitochondrial ribosomal protein L53 1451178_at chr6 C3 /// chr6 D1 243510 /// 68499 13.5 8 3743

PAGE 36

Rps26 ribosomal protein S26 1415876_a_at chr10 D3 27370 13.5 8 3744 ----1442750_at ----13.5 8 3745 Arfgap3 ADP-ribosylation factor GTPase activating protein 3 1430904_at chr15 E3 66251 13.5 8 3746 Ppih peptidyl prolyl isomerase H 1429832_at chr4 D 66101 13.5 8 3747 Pld6 phospholipase D family, member 6 1438493_at chr11 B1.3 194908 13.5 8 3748 Rpl13a ribosomal protein L13A 1433928_a_at chr7 B4|7 69.0 cM 22121 13.5 8 3749 Snrpd1 small nuclear ribonucleoprotein D1 1416336_s_at chr18 A1 20641 13.5 8 3750 Gemin8 Gem (nuclear organelle) associated protein 8 1444239_at chrX F5 237221 13.5 8 3751 ----1457839_at ----13.5 8 3752 Apob apolipoprotein B 1455593_at chr12 A1.1 238055 13.5 8 3753 Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 1418761_at chr11 D|11 55.8 cM 140486 13.5 8 3754 ----1420178_at ----13.5 8 3755 Sltm SAFB-like, transcription modulator 1456683_at chr9 D 66660 13.5 8 3756 Snhg7 Small nucleolar RNA host gene (non-protein coding) 7 1447483_s_at --72091 13.5 8 3757 Gm9800 /// Ptma predicted gene 9800 /// prothymosin alpha 1423455_at chr1 D /// chr14 A1|14 100041948 /// 19231 13.5 8 3758 Egln3 EGL nine homolog 3 (C. elegans) 1425918_at chr12 C1 112407 13.5 8 3759 Rpl39 ribosomal protein L39 1450840_a_at chrX F3 67248 13.5 8 3760 Erh enhancer of rudimentary homolog (Drosophila) 1430536_a_at chr12 D1 13877 13.5 8 3761 Slc25a33 solute carrier family 25, member 33 1424211_at chr4 E1 70556 13.5 8 3762 ----1443069_at ----13.5 8 3763 Hist1h4a /// Hist1h4b /// Hist1h4c /// Hist1h4h /// Hist1h4i /// Hist1h4j /// histone cluster 1, H4a 1422948_s_at chr13 A2-A3 /// chr13 A3.1 100041230 /// 319155 /// 319158 /// 319159 /// 319160 /// 319161 /// 32661 13.5 8 3764 Gm10164 /// Gm10223 /// Gm10294 /// LOC100041933 /// LOC100046300 /// LOC1000 ribosomal protein L17 pseudogene 1435791_x_at chr12 C2 /// chr18 E3 /// chr5 A3 /// chr7 D1 100040745 /// 100041933 /// 100042067 /// 100042880 /// 100046300 /// 1000 13.5 8 3765 Gm14303 /// Rps29 predicted gene 14303 /// ribosomal protein S29 1438859_x_at chr2 H3 20090 /// 629957 13.5 8 3766 Atp5k ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e 1450640_x_at chr5 F|5 56.0 cM 11958 13.5 8 3767 Atpif1 ATPase inhibitory factor 1 1453681_at chr4 D2.3 11983 13.5 8 3768 Pabpn1 poly(A) binding protein, nuclear 1 1422850_at chr14 C3|14 19.5 cM 54196 13.5 8 3769 Znhit3 zinc finger, HIT type 3 1452880_at chr11 C 448850 13.5 8 3770 Jmjd1c jumonji domain containing 1C 1439998_at chr10 B5.1 108829 13.5 8 3771 Rpl15 ribosomal protein L15 1449255_a_at chr14 A2|14 66480 13.5 8 3772 Gm15500 /// Rpl5 predicted gene 15500 /// ribosomal protein L5 1423665_a_at chr5 F|5 58.5 cM /// chr7 F1|7 100043295 /// 19983 13.5 8 3773 ----1457119_at ----13.5 8 3774 Eny2 enhancer of yellow 2 homolog (Drosophila) 1429412_at chr15 B3.2 223527 13.5 8 3775 H2afv H2A histone family, member V 1428029_a_at chr11 A1 77605 13.5 8 3776 Gm10443 /// Rps28 predicted gene 10443 /// ribosomal protein S28 1454778_x_at chr17 B1 /// chr6 D1 100043527 /// 54127 13.5 8 3777 Zfp276 zinc finger protein (C2H2 type) 276 1444934_at chr8 E1|8 66.0 cM 57247 13.5 8 3778 Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1453601_at chr7 D3|7 41.0 cM 269951 13.5 8 3779 Hspe1 heat shock protein 1 (chaperonin 10) 1450668_s_at chr1 C1 15528 13.5 8 3780 Rps5 ribosomal protein S5 1416054_at chr7 A1 20103 13.5 8 3781 Gm10443 /// Rps28 predicted gene 10443 /// ribosomal protein S28 1423763_x_at chr17 B1 /// chr6 D1 100043527 /// 54127 13.5 8 3782 ----1452433_at ----13.5 8 3783 Adarb2 adenosine deaminase, RNA-specific, B2 1458112_at chr13 A1 94191 13.5 8 3784 1810035L17Rik RIKEN cDNA 1810035L17 gene 1428554_a_at chr12 E 380773 13.5 8 3785 Rps10 ribosomal protein S10 1434854_a_at chr17 B1 67097 13.5 8 3786 Rps18 ribosomal protein S18 1455572_x_at chr17 B1|17 18.42 cM 20084 13.5 8 3787 Gm4149 /// Rpl37a predicted gene 4149 /// ribosomal protein L37a 1416217_a_at chr1 C3 /// chr13 C1|13 100042986 /// 19981 13.5 8 3788 Trub2 TruB pseudouridine (psi) synthase homolog 2 (E. coli) 1424610_at chr2 B 227682 13.5 8 3789 B9d1 B9 protein domain 1 1417596_at chr11 B2 27078 13.5 8 3790 Gm8186 /// Snrpg predicted gene 8186 /// small nuclear ribonucleoprotein polypeptide G 1448358_s_at chr17 A3.3 /// chr6 B1 666609 /// 68011 13.5 8 3791 Mettl13 methyltransferase like 13 1453580_at chr1 H1 71449 13.5 8 3792 Ndst3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1453777_a_at chr3 G3 83398 13.5 8 3793 Rpl27 ribosomal protein L27 1416099_at chr11 A1 19942 13.5 8 3794 Rpl23a ribosomal protein L23a 1426660_x_at chr11 B5 268449 13.5 8 3795 Rpl37a ribosomal protein L37a 1460543_x_at chr1 C3 19981 13.5 8 3796 Rps7 ribosomal protein S7 1435593_x_at chr12 C1 20115 13.5 8 3797 Gm10335 /// Rpl23a predicted gene 10335 /// ribosomal protein L23a 1437976_x_at chr10 A2 /// chr11 B5 100039571 /// 268449 13.5 8 3798 Atp5e ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1416567_s_at chr2 H4 67126 13.5 8 3799 Zfr Zinc finger RNA binding protein 1444096_at chr15 A 22763 13.5 8 3800 Bex4 brain expressed gene 4 1428209_at chrXE3|X 406217 13.5 8 3801 Carhsp1 calcium regulated heat stable protein 1 1415976_a_at chr16 A1|16 1.7 cM 52502 13.5 8 3802 Spc24 SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) 1431087_at chr9 A3 67629 13.5 8 3803 Mid1 midline 1 1422055_at chrX F5|X 74.2 cM 17318 13.5 8 3804 Foxh1 forkhead box H1 1422213_s_at chr15 D3 14106 13.5 8 3805 Elof1 elongation factor 1 homolog (ELF1, S. cerevisiae) 1423820_at chr9 A3 66126 13.5 8 3806 Snrpg small nuclear ribonucleoprotein polypeptide G 1448357_at chr6 B1 68011 13.5 8 3807 1110001A16Rik RIKEN cDNA 1110001A16 gene 1435755_at --68554 13.5 8 3808 Rps10 ribosomal protein S10 1439374_x_at chr17 B1 67097 13.5 8 3809 C630004H02Rik RIKEN cDNA C630004H02 gene 1457518_at chr11 E2 217310 13.5 8 3810 2610002D18Rik RIKEN cDNA 2610002D18 gene 1429812_at chr4 D3 69885 13.5 8 3811 Bola2 bolA-like 2 (E. coli) 1434543_a_at chr7 F3 66162 13.5 8 3812 Mfsd8 major facilitator superfamily domain containing 8 1438497_at chr3 C 72175 13.5 8 3813 Adk adenosine kinase 1449641_at chr14 A2-B 11534 13.5 8 3814 ----1434280_at ----13.5 8 3815 Atpif1 ATPase inhibitory factor 1 1448770_a_at chr4 D2.3 11983 13.5 8 3816 H2afz H2A histone family, member Z 1416415_a_at chr3 G3 51788 13.5 8 3817 Cox7a2 cytochrome c oxidase, subunit VIIa 2 1416971_at chr9 E1|9 42.0 cM 12866 13.5 8 3818 Nrf1 Nuclear respiratory factor 1 1434627_at chr6 A3.3|6 6.5 cM 18181 13.5 8 3819 ----1439307_at ----13.5 8 3820 Rps12 ribosomal protein S12 1433432_x_at chr10 A3 20042 13.5 8 3821 Meg3 maternally expressed 3 1439380_x_at chr12 F1|12 54.0 cM 17263 13.5 8 3822 Psmb3 proteasome (prosome, macropain) subunit, beta type 3 1460198_a_at chr11 D|11 58.3 cM 26446 13.5 8 3823 Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 1421786_at chr11 A3.1 19058 13.5 8 3824 Rpl10 ribosomal protein 10 1448157_s_at chrX A7.3|X 29.82 cM 110954 13.5 8 3825 Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1451262_a_at chr5 G2 231872 13.5 8 3826 Nudt5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 1448651_at chr2 A1 53893 13.5 8 3827 ----1439336_at ----13.5 8 3828 Dtymk deoxythymidylate kinase 1449116_a_at chr1 D|1 38.0 cM 21915 13.5 8 3829 4930445K14Rik RIKEN cDNA 4930445K14 gene 1453475_at chr2 H3 74886 13.5 8 3830 Rpl7a ribosomal protein L7A 1422613_a_at chr2 A3|2 18.0 cM 27176 13.5 8 3831 5730457N03Rik RIKEN cDNA 5730457N03 gene 1430678_at --70593 13.5 8 3832 Trnau1ap tRNA selenocysteine 1 associated protein 1 1428746_a_at chr4 D3|4 71787 13.5 8 3833 Snrpd2 small nuclear ribonucleoprotein D2 1452680_at chr7 A3 107686 13.5 8 3834 Msi2 Musashi homolog 2 (Drosophila) 1421231_at chr11 C 76626 13.5 8 3835 Tuba1b tubulin, alpha 1B 1423846_x_at chr15 F1 22143 13.5 8 3836 Gm10443 /// LOC100044740 /// Rps28 predicted gene 10443 /// similar to ribosomal protein S28 /// ribosomal protein S28 1451101_a_at chr17 B1 /// chr6 D1 100043527 /// 100044740 /// 54127 13.5 8 3837 Rpl3 ribosomal protein L3 1449323_a_at chr15 E1 27367 13.5 8 3838 Arglu1 arginine and glutamate rich 1 1433598_at chr8 A1.1 234023 13.5 8 3839 Rps21 ribosomal protein S21 1434358_x_at chr2 H4 66481 13.5 8 3840 Ccdc84 coiled-coil domain containing 84 1454839_a_at chr9 A5.2 382073 13.5 8 3841 ----1445456_at ----13.5 8 3842 Sfrs3 splicing factor, arginine/serine-rich 3 (SRp20) 1416150_a_at chr17 A3.3|17 11.0 cM 20383 13.5 8 3843 Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 1416938_at chr14 B 66121 13.5 8 3844 Fam60a family with sequence similarity 60, member A 1448126_at --56306 13.5 8 3845 Gins2 GINS complex subunit 2 (Psf2 homolog) 1452881_at chr8 E1 272551 13.5 8 3846 1110012J17Rik RIKEN cDNA 1110012J17 gene 1442363_at chr17 E1.1 68617 13.5 8 3847 Rps20 ribosomal protein S20 1456373_x_at chr4 A1 67427 13.5 8 3848 Plekha4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 1451907_a_at chr7 B4 69217 13.5 8 3849 Nup37 nucleoporin 37 1423969_at chr10 C2 69736 13.5 8 3850

PAGE 37

1700023F06Rik RIKEN cDNA 1700023F06 gene 1430764_at chr11 E1 69441 13.5 8 3851 2900010M23Rik RIKEN cDNA 2900010M23 gene 1448685_at chr17 B1 67267 13.5 8 3852 Apcdd1 Adenomatosis polyposis coli down-regulated 1 1443639_at chr18 E1 494504 13.5 8 3853 Rpsa ribosomal protein SA 1448245_at chr9 F4|9 71.0 cM 16785 13.5 8 3854 Nrf1 Nuclear respiratory factor 1 1445914_at chr6 A3.3|6 6.5 cM 18181 13.5 8 3855 Arhgap28 Rho GTPase activating protein 28 1458688_at chr17 E1.2 268970 13.5 8 3856 Aprt adenine phosphoribosyl transferase 1451703_s_at chr8 E1|8 67.0 cM 11821 13.5 8 3857 Slc45a4 solute carrier family 45, member 4 1433560_at chr15 D3 106068 13.5 8 3858 Gm7285 /// Rps7 predicted gene 7285 /// ribosomal protein S7 1455364_a_at chr12 C1 /// chr5 G2|5 20115 /// 640050 13.5 8 3859 Rpain RPA interacting protein 1441814_s_at chr11 B4 69723 13.5 8 3860 Gm6301 /// Rpl27 ribosomal protein L27 pseudogene /// ribosomal protein L27 1448217_a_at chr1 H3 /// chr11 A1 19942 /// 622236 13.5 8 3861 Lage3 L antigen family, member 3 1449213_at chrX A6 66192 13.5 8 3862 LOC100046668 /// Rps23 similar to yeast ribosomal protein S28 homologue /// ribosomal protein S23 1460175_at chr13 C3 100046668 /// 66475 13.5 8 3863 Plekho1 pleckstrin homology domain containing, family O member 1 1417128_at chr3 F2 67220 13.5 8 3864 Ppia peptidylprolyl isomerase A 1417451_a_at chr11 A1|11 1.0 cM 268373 13.5 8 3865 Rpain RPA interacting protein 1428828_at chr11 B4 69723 13.5 8 3866 D930016D06Rik RIKEN cDNA D930016D06 gene 1424861_at chr5 E5 100662 13.5 8 3867 Tomm7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1428214_at chr5 A3 66169 13.5 8 3868 Rps21 ribosomal protein S21 1430288_x_at chr2 H4 66481 13.5 8 3869 Hspb2 heat shock protein 2 1429888_a_at chr9 A5.3|9 29.0 cM 69253 13.5 8 3870 Rbmx RNA binding motif protein, X chromosome 1416355_at chrX A5 19655 13.5 8 3871 Nnat neuronatin 1423506_a_at chr2 H1|2 88.0 cM 18111 13.5 8 3872 ----1458200_at ----13.5 8 3873 ----1444136_at ----13.5 8 3874 Cfl2 cofilin 2, muscle 1431432_at chr12 C1 12632 13.5 8 3875 Smek1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 1457522_at chr12 E 68734 13.5 8 3876 ----1459493_at ----13.5 8 3877 ----1440892_at ----13.5 8 3878 Nfkbiz Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1457404_at chr16 C1.2-C1.3 80859 13.5 8 3879 6430537I21Rik RIKEN cDNA 6430537I21 gene 1441688_at --319654 13.5 8 3880 ----1440935_at ----13.5 8 3881 Vps18 vacuolar protein sorting 18 (yeast) 1442112_at chr2 E5 228545 13.5 8 3882 Parp1 poly (ADP-ribose) polymerase family, member 1 1443573_at chr1 H5|1 98.6 cM 11545 13.5 8 3883 ----1456347_at ----13.5 8 3884 ----1446692_at ----13.5 8 3885 6820431F20Rik RIKEN cDNA 6820431F20 gene 1436740_at chr8 A1.3 381598 13.5 8 3886 Zfp287 zinc finger protein 287 1444352_at chr11 B2 170740 13.5 8 3887 4632427E13Rik RIKEN cDNA 4632427E13 gene 1442155_at chr7 E1 666737 13.5 8 3888 Vash1 vasohibin 1 1445143_at chr12 D2 238328 13.5 8 3889 ----1439200_x_at ----13.5 8 3890 Hist1h2bc /// Hist1h2be /// Hist1h2bl /// Hist1h2bm /// Hist1h2bp /// LOC1000 histone cluster 1, H2bc 1452540_a_at chr13 A2-A3 /// chr13 A3.1 100046213 /// 319179 /// 319185 /// 319186 /// 319188 /// 665596 /// 66562 13.5 8 3891 Dusp9 dual specificity phosphatase 9 1454737_at chrX B 75590 13.5 8 3892 ----1456973_at ----13.5 8 3893 Sdr39u1 short chain dehydrogenase/reductase family 39U, member 1 1459269_at chr14 C1 654795 13.5 8 3894 Acer2 alkaline ceramidase 2 1421496_at chr4 C4 230379 13.5 8 3895 ----1426060_at ----13.5 8 3896 Hist1h3f histone cluster 1, H3f 1431231_at chr13 A2-A3|13 12.0 cM 260423 13.5 8 3897 5730405O12Rik RIKEN cDNA 5730405O12 gene 1432843_at --70488 13.5 8 3898 5930427J20Rik RIKEN cDNA 5930427J20 gene 1433086_at --77112 13.5 8 3899 9230108I15Rik RIKEN cDNA 9230108I15 gene 1438299_at chr2 H4 78078 13.5 8 3900 Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 1448096_at chr8 C5 270086 13.5 8 3901 Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 1436602_x_at chr2 A2|2 18.0 cM 12287 13.5 8 3902 ----1444195_at ----13.5 8 3903 5930436O19Rik RIKEN cDNA 5930436O19 gene 1430585_at chr17 E4 77068 13.5 8 3904 ----1440219_at ----13.5 8 3905 Tns3 tensin 3 1446636_at chr11 A1 319939 13.5 8 3906 ----1445941_at ----13.5 8 3907 Ss18 synovial sarcoma translocation, Chromosome 18 1436257_at chr18 B1 268996 13.5 8 3908 5930433N17Rik RIKEN cDNA 5930433N17 gene 1440721_at --399623 13.5 8 3909 AA409587 expressed sequence AA409587 1442358_at --101447 13.5 8 3910 Scmh1 Sex comb on midleg homolog 1 1441573_at chr4 D1-D2|4 56.5 cM 29871 13.5 8 3911 ----1442886_at ----13.5 8 3912 Ahctf1 AT hook containing transcription factor 1 1446472_at chr1 H4|1 102.0 cM 226747 13.5 8 3913 Ypel1 yippee-like 1 (Drosophila) 1431782_s_at chr16 A3 106369 13.5 8 3914 ----1443400_at ----13.5 8 3915 ----1459373_at ----13.5 8 3916 ----1444130_at ----13.5 8 3917 4933438A12Rik RIKEN cDNA 4933438A12 gene 1432389_at --71243 13.5 8 3918 4632427E13Rik RIKEN cDNA 4632427E13 gene 1456201_at chr7 E1 666737 13.5 8 3919 Kdm5a lysine (K)-specific demethylase 5A 1444842_at chr6 F1 214899 13.5 8 3920 ----1438508_at ----13.5 8 3921 4930420K17Rik RIKEN cDNA 4930420K17 gene 1440349_at chr5 A1 652925 13.5 8 3922 MGC7817 hypothetical protein LOC620031 1425424_at chr6 G2 620031 13.5 8 3923 Slc44a2 solute carrier family 44, member 2 1438860_a_at chr9 A3 68682 13.5 8 3924 Wdr26 WD repeat domain 26 1438234_at chr1 H4 226757 13.5 8 3925 Gm8276 /// Pabpc1 predicted gene 8276 /// poly(A) binding protein, cytoplasmic 1 1453840_at chr15 C /// chr3 D|3 18458 /// 666756 13.5 8 3926 Wapal wings apart-like homolog (Drosophila) 1442426_at chr14 B 218914 13.5 8 3927 Ndufb8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 1448198_a_at chr19 D1 67264 13.5 8 3928 Psma1 proteasome (prosome, macropain) subunit, alpha type 1 1458292_at chr7 F1|7 53.0 cM 26440 13.5 8 3929 ----1427820_at ----13.5 8 3930 D530037H12Rik RIKEN cDNA D530037H12 gene 1437917_at --96893 13.5 8 3931 ----1446921_at ----13.5 8 3932 ----1439877_at ----13.5 8 3933 Gpr33 G protein-coupled receptor 33 1451708_at chr12 C1 14762 13.5 8 3934 ----1437600_at ----13.5 8 3935 AI317158 expressed sequence AI317158 1445481_at --106549 13.5 8 3936 Lims1 LIM and senescent cell antigen-like domains 1 1441411_at chr10 B4|10 30.0 cM 110829 13.5 8 3937 ----1444858_at ----13.5 8 3938 Rbm39 RNA binding motif protein 39 1446148_x_at chr2 H1 170791 13.5 8 3939 Cxcl14 chemokine (C-X-C motif) ligand 14 1418457_at chr13 B1 57266 13.5 8 3940 4632427E13Rik RIKEN cDNA 4632427E13 gene 1429331_at chr7 E1 666737 13.5 8 3941 Calu calumenin 1441477_at chr6 A3.3 12321 13.5 8 3942 LOC433064 /// Ppih similar to peptidyl prolyl isomerase H /// peptidyl prolyl isomerase H 1424136_a_at chr17 A1 /// chr4 D 433064 /// 66101 13.5 8 3943 Tmtc2 transmembrane and tetratricopeptide repeat containing 2 1441033_at chr10 D1 278279 13.5 8 3944 ----1444100_at ----13.5 8 3945 4833416J08Rik RIKEN cDNA 4833416J08 gene 1430404_at --75771 13.5 8 3946 Rbm25 RNA binding motif protein 25 1437862_at chr12 D1 67039 13.5 8 3947 Rdh1 retinol dehydrogenase 1 (all trans) 1421702_at chr10 D3|10 70.0 cM 107605 13.5 8 3948 1200009I06Rik RIKEN cDNA 1200009I06 gene 1428420_a_at chr12 F2 74190 13.5 8 3949 2810410L24Rik RIKEN cDNA 2810410L24 gene 1429510_at chr11 E2 100042332 13.5 8 3950 ----1442629_at ----13.5 8 3951 Lman1 lectin, mannose-binding, 1 1444037_at chr18 E1 70361 13.5 8 3952 Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 1440464_at chr8 A1.1|8 1.0 cM 15568 13.5 8 3953 Fam115a family with sequence similarity 115, member A 1453437_at chr6 B2|6 77574 13.5 8 3954 Kcnq1ot1 KCNQ1 overlapping transcript 1 1442029_at chr7 F5|7 69.3 cM 63830 13.5 8 3955 ----1456386_at ----13.5 8 3956 8030447M02Rik RIKEN cDNA 8030447M02 gene 1458601_at --399578 13.5 8 3957

PAGE 38

Mrpl11 mitochondrial ribosomal protein L11 1437839_x_at chr19 A 66419 13.5 8 3958 A430081F14Rik RIKEN cDNA A430081F14 gene 1457297_at --320639 13.5 8 3959 ----1459256_at ----13.5 8 3960 A430102J17Rik RIKEN cDNA A430102J17 gene 1438895_at --109200 13.5 8 3961 Cbara1 calcium binding atopy-related autoantigen 1 1439501_at chr10 B4 216001 13.5 8 3962 Fbxl7 F-box and leucine-rich repeat protein 7 1440441_at chr15 B1 448987 13.5 8 3963 Ttc3 tetratricopeptide repeat domain 3 1441684_at chr16 C3.3-4|16 67.9 cM 22129 13.5 8 3964 ----1439652_at ----13.5 8 3965 9030425P06Rik RIKEN cDNA 9030425P06 gene 1444456_at --319680 13.5 8 3966 ----1442955_at ----13.5 8 3967 5730507N06Rik RIKEN cDNA 5730507N06 gene 1457642_at --70622 13.5 8 3968 Mbnl2 muscleblind-like 2 1457477_at chr14 E4 105559 13.5 8 3969 Lbx2 ladybird homeobox homolog 2 (Drosophila) 1420714_at chr6 C3|6 35.0 cM 16815 13.5 8 3970 4633401B06Rik RIKEN cDNA 4633401B06 gene 1429822_at --70828 13.5 8 3971 C78692 expressed sequence C78692 1446288_at --97148 13.5 8 3972 ----1459497_at ----13.5 8 3973 Hif3a /// LOC641092 hypoxia inducible factor 3, alpha subunit /// similar to hypoxia inducible factor 3, alpha subunit 1425429_s_at chr7 A2 53417 /// 641092 13.5 8 3974 Mecp2 methyl CpG binding protein 2 1438538_at chrX A7.3|X 29.6 cM 17257 13.5 8 3975 B930025B16Rik RIKEN cDNA B930025B16 gene 1458376_at --503851 13.5 8 3976 4932431P20Rik RIKEN cDNA 4932431P20 gene 1432882_at chr7 B1 114675 13.5 8 3977 Tubb2c /// Tubb2c-ps2 tubulin, beta 2C /// tubulin, beta 2c, pseudogene 2 1438622_x_at chr1 A5 /// chr2 A3 227613 /// 665829 13.5 8 3978 ----1445773_at ----13.5 8 3979 ----1440431_at ----13.5 8 3980 ----1445933_at ----13.5 8 3981 Psma7 proteasome (prosome, macropain) subunit, alpha type 7 1423568_at chr2 H4 26444 13.5 8 3982 ----1446969_at ----13.5 8 3983 Clasp1 CLIP associating protein 1 1460102_at chr1 E2 76707 13.5 8 3984 Ttc14 tetratricopeptide repeat domain 14 1456430_at chr3 B 67120 13.5 8 3985 Fubp1 far upstream element (FUSE) binding protein 1 1437544_at chr3 H3|3 70.5 cM 51886 13.5 8 3986 AW556556 expressed sequence AW556556 1442064_at --106817 13.5 8 3987 Cdv3 carnitine deficiency-associated gene expressed in ventricle 3 1440332_at chr9 F1 321022 13.5 8 3988 E230012J19Rik RIKEN cDNA E230012J19 gene 1458156_at --319664 13.5 8 3989 Polb polymerase (DNA directed), beta 1439840_at chr8 A2|8 8.0 cM 18970 13.5 8 3990 ----1443592_at ----13.5 8 3991 Snrnp25 small nuclear ribonucleoprotein 25 (U11/U12) 1428004_at chr11 A4 78372 13.5 8 3992 ----1446475_at ----13.5 8 3993 ----1439227_at ----13.5 8 3994 Itsn2 intersectin 2 1445375_at chr12 A1.1 20403 13.5 8 3995 ----1443770_x_at ----13.5 8 3996 ----1460032_at ----13.5 8 3997 LOC553096 hypothetical LOC553096 1442320_at --553096 13.5 8 3998 E330024J20Rik RIKEN cDNA E330024J20 gene 1445743_at --320654 13.5 8 3999 Rian RNA imprinted and accumulated in nucleus 1428055_at chr12 F1|12 54.5 cM 75745 13.5 8 4000 Sf3b3 Splicing factor 3b, subunit 3 1430075_at chr8 E1 101943 13.5 8 4001 ----1438072_at ----13.5 8 4002 ----1458661_at ----13.5 8 4003 ----1440010_at ----13.5 8 4004 4933426B08Rik RIKEN cDNA 4933426B08 gene 1432153_at --71173 13.5 8 4005 5730488B01Rik RIKEN cDNA 5730488B01 gene 1432886_at chr4 B1 70602 13.5 8 4006 Sacm1l SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae) 1438900_at chr9 F|9 70.8 cM 83493 13.5 8 4007 D2Ertd93e DNA segment, Chr 2, ERATO Doi 93, expressed 1458414_at chr2 101.0 cM 51842 13.5 8 4008 Cldn6 claudin 6 1417845_at chr17 A3.3 54419 13.5 8 4009 Tac1 tachykinin 1 1431883_at chr6 A1|6 5.0 cM 21333 13.5 8 4010 Amn1 Antagonist of mitotic exit network 1 homolog (S. cerevisiae) 1441141_at chr6 G3 232566 13.5 8 4011 Nsd1 Nuclear receptor-binding SET-domain protein 1 1456916_at chr13 B1 18193 13.5 8 4012 Adk adenosine kinase 1446068_at chr14 A2-B 11534 13.5 8 4013 AI480624 expressed sequence AI480624 1442197_at --102540 13.5 8 4014 ----1457988_at ----13.5 8 4015 Ddhd2 DDHD domain containing 2 1444320_at chr8 A3 72108 13.5 8 4016 Phf20l1 PHD finger protein 20-like 1 1457264_at chr15 D2 239510 13.5 8 4017 6720475J19Rik RIKEN cDNA 6720475J19 gene 1423071_x_at chr19 A 68157 13.5 8 4018 ----1445966_at ----13.5 8 4019 ----1440790_x_at ----13.5 8 4020 Hmga2 high mobility group AT-hook 2 1450780_s_at chr10 D2|10 67.5 cM 15364 13.5 8 4021 ----1459005_at ----13.5 8 4022 Rae1 RAE1 RNA export 1 homolog (S. pombe) 1444256_at chr2 H3|2 103.0 cM 66679 13.5 8 4023 4921513D23Rik RIKEN cDNA 4921513D23 gene 1459879_at chr16 A1 223989 13.5 8 4024 ----1446001_at ----13.5 8 4025 ----1457480_at ----13.5 8 4026 9630010G10Rik RIKEN cDNA 9630010G10 gene 1460121_at --399612 13.5 8 4027 LOC100134980 hypothetical LOC100134980 1425421_at chr7 F3 100134980 13.5 8 4028 Taf1d TATA box binding protein (Tbp)-associated factor, RNA polymerase I, D 1457292_at chr9 A3 75316 13.5 8 4029 A930004J17Rik RIKEN cDNA A930004J17 gene 1457760_at --319635 13.5 8 4030 ----1447911_at ----13.5 8 4031 ----1445689_at ----13.5 8 4032 ----1456216_at ----13.5 8 4033 5830427D02Rik RIKEN cDNA 5830427D02 gene 1431528_at --76042 13.5 8 4034 Enho energy homeostasis associated 1454585_at chr4 A5 69638 13.5 8 4035 H3f3a H3 histone, family 3A 1442087_at chr1 D2.3 15078 13.5 8 4036 C130015C19 hypothetical LOC403342 1457464_at --403342 13.5 8 4037 Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1437797_at chr5 F|5 65.0 cM 11938 13.5 8 4038 ----1438739_at ----13.5 8 4039 Crkrs CDC2-related kinase, arginine/serine-rich 1443294_at chr11 D|11 56.0 cM 69131 13.5 8 4040 ----1445235_at ----13.5 8 4041 1810013D15Rik RIKEN cDNA 1810013D15 gene 1454271_at --69042 13.5 8 4042 Sip1 Survival of motor neuron protein interacting protein 1 1458627_at chr12 C2 66603 13.5 8 4043 Mucl1 mucin-like 1 1420466_at chr15 F3|15 58.1 cM 20771 13.5 8 4044 D9Ertd306e DNA segment, Chr 9, ERATO Doi 306, expressed 1442484_at chr9 50.0 cM 52203 13.5 8 4045 Cwc22 /// Gm14702 /// Gm2100 /// Gm2870 /// Gm2968 /// Gm3322 /// Gm3697 /// CWC22 spliceosome-associated protein homolog (S. cerevisiae) 1424607_a_at chr15 D1|15 /// chr2 C3 /// chr3 B|3 /// chr3 H3|3 /// chr4 100039204 /// 100040620 /// 100040790 /// 100041416 /// 100042151 /// 1000 13.5 8 4046 ----1445322_x_at ----13.5 8 4047 Hmmr hyaluronan mediated motility receptor (RHAMM) 1429871_at chr11 A5|11 19.0 cM 15366 13.5 8 4048 Ppih peptidyl prolyl isomerase H 1431506_s_at chr4 D 66101 13.5 8 4049 Trpm7 transient receptor potential cation channel, subfamily M, member 7 1431355_s_at chr2 F2 58800 13.5 8 4050 Tmem207 transmembrane protein 207 1445371_at chr16 B2|16 100043057 13.5 8 4051 ----1446946_at ----13.5 8 4052 Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 1453251_at chr9 F2 72831 13.5 8 4053 Nr1i2 nuclear receptor subfamily 1, group I, member 2 1425723_at chr16 B3 18171 13.5 8 4054 ----1440055_at ----13.5 8 4055 ----1447951_at ----13.5 8 4056 ----1458746_at ----13.5 8 4057 B230213L16Rik RIKEN cDNA B230213L16 gene 1446443_at --320943 13.5 8 4058 ----1447109_at ----13.5 8 4059 ----1457483_at ----13.5 8 4060 Papola poly (A) polymerase alpha 1424217_at chr12 F1 18789 13.5 8 4061 ----1458121_at ----13.5 8 4062 ----1445947_at ----13.5 8 4063 ----1446012_at ----13.5 8 4064

PAGE 39

Hpvc-ps Human papillomavirus 18 E5 central sequence motif, pseudogene 1456880_at chr5 G1.3|5 72.0 cM 15456 13.5 8 4065 Bcl9 B-cell CLL/lymphoma 9 1455565_at chr3 F2 77578 13.5 8 4066 Luc7l2 LUC7-like 2 (S. cerevisiae) 1436767_at chr6 B1 192196 13.5 8 4067 Mtdh Metadherin 1456548_at chr15 B3.3|15 53.5 cM 67154 13.5 8 4068 Taf15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1438130_at chr11 B5 70439 13.5 8 4069 AI605517 expressed sequence AI605517 1457797_at --106622 13.5 8 4070 ----1446571_at ----13.5 8 4071 ----1456849_at ----13.5 8 4072 ----1442735_at ----13.5 8 4073 ----1444345_at ----13.5 8 4074 ----1459301_at ----13.5 8 4075 Tmem178 transmembrane protein 178 1429175_at chr17 E3 68027 13.5 8 4076 ----1447523_at ----13.5 8 4077 Smc2 Structural maintenance of chromosomes 2 1458479_at chr4 B3|4 18.5 cM 14211 13.5 8 4078 ----1457910_at ----13.5 8 4079 ----1446410_at ----13.5 8 4080 Npat nuclear protein in the AT region 1459185_at chr9 A5.3 244879 13.5 8 4081 Tubb2a-ps2 tubulin, beta 2a, pseudogene 2 1449683_x_at chr12 A1.1 627110 13.5 8 4082 ----1459512_at ----13.5 8 4083 Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 1431388_at chr7 C 67973 13.5 8 4084 D2Ertd612e DNA segment, Chr 2, ERATO Doi 612, expressed 1438222_at chr2 31.0 cM 51922 13.5 8 4085 Aebp2 AE binding protein 2 1455616_at chr6 G1 11569 13.5 8 4086 ----1444411_at ----13.5 8 4087 ----1446627_at ----13.5 8 4088 ----1437883_s_at ----13.5 8 4089 Golim4 golgi integral membrane protein 4 1459045_at chr3 E3 73124 13.5 8 4090 5830415B17Rik RIKEN cDNA 5830415B17 gene 1433242_at --76012 13.5 8 4091 9430091N11Rik RIKEN cDNA 9430091N11 gene 1442352_at --319244 13.5 8 4092 A430108E01Rik RIKEN cDNA A430108E01 gene 1438049_at chr8 A1.3 384382 13.5 8 4093 Ep400 E1A binding protein p400 1440751_at chr5 F 75560 13.5 8 4094 ----1445012_at ----13.5 8 4095 Ccnt2 cyclin T2 1453399_at chr1 E3 72949 13.5 8 4096 Ptprs protein tyrosine phosphatase, receptor type, S 1436855_at chr17 D|17 33.8 cM 19280 13.5 8 4097 Diap1 diaphanous homolog 1 (Drosophila) 1445391_at chr18 B3|18 16.0 cM 13367 13.5 8 4098 Dctpp1 dCTP pyrophosphatase 1 1416439_at chr7 F3 66422 13.5 8 4099 Itch itchy, E3 ubiquitin protein ligase 1431316_at chr2 H1|2 89.0 cM 16396 13.5 8 4100 6030487A22Rik RIKEN cDNA 6030487A22 gene 1441195_at --402755 13.5 8 4101 Zmat2 zinc finger, matrin type 2 1446079_at chr18 B2 66492 13.5 8 4102 ----1446886_at ----13.5 8 4103 Ube2i ubiquitin-conjugating enzyme E2I 1453189_at chr17 A3.3 22196 13.5 8 4104 Flt4 FMS-like tyrosine kinase 4 1421442_at chr11 A5-B1|11 25.0 cM 14257 13.5 8 4105 Usmg5 upregulated during skeletal muscle growth 5 1448179_at chr19 D2 66477 13.5 8 4106 D11Ertd326e DNA segment, Chr 11, ERATO Doi 326, expressed 1449759_at chr11 11.0 cM 52574 13.5 8 4107 Strn3 Striatin, calmodulin binding protein 3 1441266_at chr12 C1 94186 13.5 8 4108 Kdm5b lysine (K)-specific demethylase 5B 1457482_at chr1 E4|1 72.0 cM 75605 13.5 8 4109 ----1440035_at ----13.5 8 4110 ----1457398_at ----13.5 8 4111 6720427H10Rik RIKEN cDNA 6720427H10 gene 1431118_at --77884 13.5 8 4112 8030497I03Rik RIKEN cDNA 8030497I03 gene 1442824_at --399593 13.5 8 4113 Zfp397 zinc finger protein 397 1443956_at chr18 A2 69256 13.5 8 4114 ----1457360_at ----13.5 8 4115 Ncaph2 non-SMC condensin II complex, subunit H2 1429477_at chr15 E3|15 49.9 cM 52683 13.5 8 4116 ----1442322_at ----13.5 8 4117 Phf6 PHD finger protein 6 1430415_at chrX A4 70998 13.5 8 4118 ----1443926_at ----13.5 8 4119 ----1446593_at ----13.5 8 4120 9030607L20Rik RIKEN cDNA 9030607L20 gene 1430103_at chr2 H1 71513 13.5 8 4121 Cux1 Cut-like homeobox 1 1441956_s_at chr5 G2|5 78.0 cM 13047 13.5 8 4122 Snrnp48 small nuclear ribonucleoprotein 48 (U11/U12) 1437180_at chr13 A5 67797 13.5 8 4123 ----1441463_at ----13.5 8 4124 ----1443085_at ----13.5 8 4125 ----1441683_at ----13.5 8 4126 Saps3 SAPS domain family, member 3 1454030_at chr19 A 52036 13.5 8 4127 Ubc ubiquitin C 1454373_x_at chr5 G1.1|5 64.0 cM 22190 13.5 8 4128 Glb1l galactosidase, beta 1-like 1420247_at chr1 C3 74577 13.5 8 4129 ----1440903_at ----13.5 8 4130 2210411K19Rik /// Rpl41 RIKEN cDNA 2210411K19 gene /// ribosomal protein L41 1454639_x_at chr10 D3 67945 /// 70164 13.5 8 4131 ----1458947_at ----13.5 8 4132 Fip1l1 FIP1 like 1 (S. cerevisiae) 1443586_at chr5 D 66899 13.5 8 4133 ----1439138_at ----13.5 8 4134 ----1440448_at ----13.5 8 4135 ----1442056_at ----13.5 8 4136 ----1459441_at ----13.5 8 4137 Gpr20 G protein-coupled receptor 20 1440021_at chr15 D3 239530 13.5 8 4138 Ttk Ttk protein kinase 1442594_at chr9 E2 22137 13.5 8 4139 Rbm39 RNA binding motif protein 39 1446147_at chr2 H1 170791 13.5 8 4140 C230037E05Rik RIKEN cDNA C230037E05 gene 1458942_at --30910 13.5 8 4141 A430107O13Rik RIKEN cDNA A430107O13 gene 1459878_a_at chr6 A3.1 214642 13.5 8 4142 Riok1 RIO kinase 1 (yeast) 1425358_at chr13 A3.3 71340 13.5 8 4143 Evl Ena-vasodilator stimulated phosphoprotein 1458889_at chr12 F2 14026 13.5 8 4144 BC023969 cDNA sequence BC023969 1445226_at --407828 13.5 8 4145 ----1448018_at ----13.5 8 4146 Top1 topoisomerase (DNA) I 1438495_at chr2 H2-3|2 92.0 cM 21969 13.5 8 4147 Unc84b unc-84 homolog B (C. elegans) 1439238_at chr15 E1 223697 13.5 8 4148 Ap2a2 adaptor protein complex AP-2, alpha 2 subunit 1432007_s_at chr7 F5 11772 13.5 8 4149 Rtn4 reticulon 4 1435284_at chr11 A3.3 68585 13.5 8 4150 ----1445638_at ----13.5 8 4151 A130001G05Rik RIKEN cDNA A130001G05 gene 1441068_at --320704 13.5 8 4152 ----1447408_at ----13.5 8 4153 8030448K23Rik RIKEN cDNA 8030448K23 gene 1459341_at --320826 13.5 8 4154 Mdfi MyoD family inhibitor 1425924_at chr17 C|17 24.0 cM 17240 13.5 8 4155 Sipa1l1 signal-induced proliferation-associated 1 like 1 1440647_at chr12 D1 217692 13.5 8 4156 ----1440304_at ----13.5 8 4157 9130208E07Rik RIKEN cDNA 9130208E07 gene 1427425_at --77670 13.5 8 4158 5830418K08Rik RIKEN cDNA 5830418K08 gene 1456296_at chr9 A2 319675 13.5 8 4159 Psma3 Proteasome (prosome, macropain) subunit, alpha type 3 1441707_at chr12 C3 19167 13.5 8 4160 Rbbp4 retinoblastoma binding protein 4 1456260_at --19646 13.5 8 4161 AA409749 expressed sequence AA409749 1420161_at --103086 13.5 8 4162 Tspy-ps testis specific protein-Y encoded, pseudogene 1427636_at chrY A1 22109 13.5 8 4163 Nfib nuclear factor I/B 1438244_at chr4 C4-C6|4 38.6 cM 18028 13.5 8 4164 ----1442109_at ----13.5 8 4165 Fn1 fibronectin 1 1437218_at chr1 C1-C5|1 36.1 cM 14268 13.5 8 4166 ----1443231_at ----13.5 8 4167 ----1446565_at ----13.5 8 4168 Trim35 tripartite motif-containing 35 1429494_at chr14 D1 66854 13.5 8 4169 Btg1 B-cell translocation gene 1, anti-proliferative 1442018_at chr10 C3 12226 13.5 8 4170 D230040J21Rik RIKEN cDNA D230040J21 gene 1439330_at --320216 13.5 8 4171

PAGE 40

----1457053_at ----13.5 8 4172 Rad23b RAD23b homolog (S. cerevisiae) 1456822_at chr4 B3 19359 13.5 8 4173 Pus3 pseudouridine synthase 3 1433104_at chr9 A5.3 67049 13.5 8 4174 ----1457206_at ----13.5 8 4175 Pmm2 phosphomannomutase 2 1439953_at chr16 A1 54128 13.5 8 4176 Usp36 ubiquitin specific peptidase 36 1458311_at chr11 E2 72344 13.5 8 4177 Gpc6 glypican 6 1441438_at chr14 E4 23888 13.5 8 4178 Taf7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor 1441982_at chr18 B3 24074 13.5 8 4179 ----1442682_at ----13.5 8 4180 Cwc22 /// Gm14702 /// Gm2100 /// Gm2870 /// Gm2968 /// Gm3322 /// Gm3697 /// CWC22 spliceosome-associated protein homolog (S. cerevisiae) 1424609_a_at chr15 D1|15 /// chr2 C3 /// chr3 B|3 /// chr3 H3|3 /// chr4 100039204 /// 100040620 /// 100040790 /// 100041416 /// 100042151 /// 1000 13.5 8 4181 ----1446967_at ----13.5 8 4182 Pcdhgc4 protocadherin gamma subfamily C, 4 1438103_at chr18 B3 93707 13.5 8 4183 Meis2 Meis homeobox 2 1440091_at chr2 E4-E5|2 64.0 cM 17536 13.5 8 4184 ----1443075_at ----13.5 8 4185 ----1456547_at ----13.5 8 4186 Nxf1 Nuclear RNA export factor 1 homolog (S. cerevisiae) 1439092_at chr19 A|19 5.0 cM 53319 13.5 8 4187 ----1456553_at ----13.5 8 4188 ----1441526_at ----13.5 8 4189 5830407P18Rik RIKEN cDNA 5830407P18 gene 1430646_at --78818 13.5 8 4190 ----1443513_at ----13.5 8 4191 ----1438353_at ----13.5 8 4192 Dusp9 dual specificity phosphatase 9 1433845_x_at chrX B 75590 13.5 8 4193 Mbtd1 mbt domain containing 1 1441100_at chr11 D 103537 13.5 8 4194 Saps3 SAPS domain family, member 3 1439161_at chr19 A 52036 13.5 8 4195 ----1458525_at ----13.5 8 4196 ----1438301_at ----13.5 8 4197 ----1441498_at ----13.5 8 4198 Tra2b transformer 2 beta homolog (Drosophila) 1441466_at chr16 B1 20462 13.5 8 4199 ----1442163_at ----13.5 8 4200 ----1457971_at ----13.5 8 4201 ----1442760_x_at ----13.5 8 4202 Fus fusion, derived from t(12;16) malignant liposarcoma (human) 1455831_at chr7 F3 233908 13.5 8 4203 Pvt1 plasmacytoma variant translocation 1 1450541_at chr15 D2-D3|15 32.0 cM 19296 13.5 8 4204 AY036118 cDNA sequence AY036118 1421754_at chr17 B1 170798 13.5 8 4205 Dnajc1 DnaJ (Hsp40) homolog, subfamily C, member 1 1447649_x_at chr2 A2 13418 13.5 8 4206 Gatad2a GATA zinc finger domain containing 2A 1445239_at chr8 B3.3 234366 13.5 8 4207 Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 1441536_at --208715 13.5 8 4208 ----1444017_at ----13.5 8 4209 Rnps1 ribonucleic acid binding protein S1 1437359_at chr17 A3.3 19826 13.5 8 4210 ----1442946_at ----13.5 8 4211 C030040A22Rik RIKEN cDNA C030040A22 gene 1444353_at --320771 13.5 8 4212 Wdr33 WD repeat domain 33 1453322_at chr18 B3 74320 13.5 8 4213 Med13l mediator complex subunit 13-like 1453906_at chr5 F 76199 13.5 8 4214 ----1427809_at ----13.5 8 4215 ----1445965_at ----13.5 8 4216 4921507H08Rik RIKEN cDNA 4921507H08 gene 1432966_at --70838 13.5 8 4217 ----1458127_at ----13.5 8 4218 Pafah1b1 Platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 1439656_at chr11 B3|11 44.0 cM 18472 13.5 8 4219 A430107O13Rik RIKEN cDNA A430107O13 gene 1447948_at chr6 A3.1 214642 13.5 8 4220 ----1442737_at ----13.5 8 4221 4632427E13Rik RIKEN cDNA 4632427E13 gene 1429332_at chr7 E1 666737 13.5 8 4222 Enah Enabled homolog (Drosophila) 1442223_at chr1 H5|1 98.7 cM 13800 13.5 8 4223 Rabepk Rab9 effector protein with kelch motifs 1454449_at chr2 B 227746 13.5 8 4224 Pcp4l1 Purkinje cell protein 4-like 1 1452913_at chr1 H3 66425 13.5 8 4225 5730601F06Rik RIKEN cDNA 5730601F06 gene 1457913_at chr9 A3 77519 13.5 8 4226 Trps1 trichorhinophalangeal syndrome I (human) 1457445_at chr15 C|15 30.1 cM 83925 13.5 8 4227 Ints6 integrator complex subunit 6 1443128_at chr14 C3 18130 13.5 8 4228 ----1457577_at ----13.5 8 4229 Trp63 transformation related protein 63 1459581_at chr16 B1|16 19.3 cM 22061 13.5 8 4230 6820431F20Rik RIKEN cDNA 6820431F20 gene 1429882_at chr8 A1.3 381598 13.5 8 4231 Nisch nischarin 1433758_at chr14 B 64652 13.5 8 4232 Ipo7 importin 7 1442511_at chr7 F1 233726 13.5 8 4233 Pitpnm3 PITPNM family member 3 1445004_a_at chr11 B4 327958 13.5 8 4234 Hist1h3a /// Hist1h3b /// Hist1h3c /// Hist1h3d /// Hist1h3e /// Hist1h3f /// histone cluster 1, H3a 1460314_s_at chr13 A2-A3 /// chr13 A2-A3|13 12.0 cM /// chr3 F1-F2 /// c 15077 /// 260423 /// 319148 /// 319149 /// 319150 /// 319151 /// 319152 // 13.5 8 4235 3830417A13Rik RIKEN cDNA 3830417A13 gene 1430162_at chrX A6 70696 13.5 8 4236 ----1443435_at ----13.5 8 4237 Gspt1 G1 to S phase transition 1 1446550_at chr16 A1|16 3.8 cM 14852 13.5 8 4238 Oaz3 ornithine decarboxylase antizyme 3 1437010_a_at chr3 F2 53814 13.5 8 4239 ----1457615_at ----13.5 8 4240 Tet2 Tet oncogene family member 2 1438781_at chr3 G3 214133 13.5 8 4241 Chd8 chromodomain helicase DNA binding protein 8 1457712_at chr14 C2 67772 13.5 8 4242 9130004J05Rik RIKEN cDNA 9130004J05 gene 1430191_at --71603 13.5 8 4243 ----1442150_at ----13.5 8 4244 D19Ertd409e DNA segment, Chr 19, ERATO Doi 409, expressed 1440417_at chr19 43.0 cM 52016 13.5 8 4245 Bcl2 B-cell leukemia/lymphoma 2 1440770_at chr1 E2.1|1 59.8 cM 12043 13.5 8 4246 D230040A04Rik RIKEN cDNA D230040A04 gene 1442151_at --414113 13.5 8 4247 ----1444538_at ----13.5 8 4248 ----1446780_at ----13.5 8 4249 ----1444175_at ----13.5 8 4250 Senp6 SUMO/sentrin specific peptidase 6 1445387_at chr9 E1 215351 13.5 8 4251 Brd8 bromodomain containing 8 1452350_at chr18 B1 78656 13.5 8 4252 ----1439136_at ----13.5 8 4253 ----1444430_at ----13.5 8 4254 1700109H08Rik RIKEN cDNA 1700109H08 gene 1453447_at chr5 A1 77036 13.5 8 4255 ----1439651_at ----13.5 8 4256 ----1440624_at ----13.5 8 4257 ----1445361_at ----13.5 8 4258 Pgc progastricsin (pepsinogen C) 1415786_at chr17 C|17 30.0 cM 109820 13.5 9 4259 ----1442535_at ----13.5 9 4260 Rab8b RAB8B, member RAS oncogene family 1426800_at chr9 C 235442 13.5 9 4261 ----1441041_at ----13.5 9 4262 ----1446480_at ----13.5 9 4263 3110005L21Rik RIKEN cDNA 3110005L21 gene 1453646_at --73104 13.5 9 4264 ----1457356_at ----13.5 9 4265 ----1443544_at ----13.5 9 4266 ----1457047_at ----13.5 9 4267 ----1447177_at ----13.5 9 4268 Fam19a4 family with sequence similarity 19, member A4 1435610_at chr6 D3 320701 13.5 9 4269 ----1445916_at ----13.5 9 4270 AA407881 expressed sequence AA407881 1440717_at --101931 13.5 9 4271 ----1441679_at ----13.5 9 4272 D930017J03Rik RIKEN cDNA D930017J03 gene 1456099_at --320391 13.5 9 4273 AL024213 expressed sequence AL024213 1457128_at --105253 13.5 9 4274 Zdhhc13 Zinc finger, DHHC domain containing 13 1460048_at chr7 B4 243983 13.5 9 4275 Arih2 ariadne homolog 2 (Drosophila) 1445934_at chr9 F2 23807 13.5 9 4276 ----1458521_at ----13.5 9 4277 Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1430161_at chr12 D3 78920 13.5 9 4278

PAGE 41

Erlin1 ER lipid raft associated 1 1441344_at chr19 C3 226144 13.5 9 4279 Atad2 ATPase family, AAA domain containing 2 1443146_at chr15 D2 70472 13.5 9 4280 ----1456832_at ----13.5 9 4281 Tmem57 Transmembrane protein 57 1458545_at chr4 D3|4 65.69 cM 66146 13.5 9 4282 2510017J16Rik RIKEN cDNA 2510017J16 gene 1430393_at --66574 13.5 9 4283 Lax1 lymphocyte transmembrane adaptor 1 1438687_at chr1 E4 240754 13.5 9 4284 ----1442422_at ----13.5 9 4285 Rbm27 RNA binding motif protein 27 1458013_at chr18 B3 225432 13.5 9 4286 ----1441505_at ----13.5 9 4287 Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 1431300_at chr4 C6 73094 13.5 9 4288 Gabrp gamma-aminobutyric acid (GABA) A receptor, pi 1451424_at chr11 A4 216643 13.5 9 4289 5830411J07Rik RIKEN cDNA 5830411J07 gene 1420758_at chr2 C2 74742 13.5 9 4290 Ednra endothelin receptor type A 1440093_at --13617 13.5 9 4291 ----1438848_at ----13.5 9 4292 ----1443731_at ----13.5 9 4293 ----1457746_at ----13.5 9 4294 ----1448090_at ----13.5 9 4295 ----1458526_at ----13.5 9 4296 Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 1421924_at chr6 F2|6 59.0 cM 20527 13.5 9 4297 ----1444140_at ----13.5 9 4298 ----1459009_at ----13.5 9 4299 Spanxn4 SPANX family, member N4 1438384_at chr12 C1 73309 13.5 9 4300 ----1442675_at ----13.5 9 4301 C76555 expressed sequence C76555 1442944_at --97125 13.5 9 4302 D13Ertd666e DNA segment, Chr 13, ERATO Doi 666, expressed 1440292_at chr13 37.0 cM 52695 13.5 9 4303 ----1443602_at ----13.5 9 4304 5730446D14Rik RIKEN cDNA 5730446D14 gene 1429398_at chr6 B3 66640 13.5 9 4305 ----1442014_at ----13.5 9 4306 ----1435708_at ----13.5 9 4307 ----1438960_at ----13.5 9 4308 ----1447891_at ----13.5 9 4309 ----1444043_at ----13.5 9 4310 Ints10 integrator complex subunit 10 1439712_at chr8 C1 70885 13.5 9 4311 4833441D16Rik RIKEN cDNA 4833441D16 gene 1456706_at --108962 13.5 9 4312 Hbb-y hemoglobin Y, beta-like embryonic chain 1436717_x_at chr7 E3|7 49.95 cM 15135 13.5 9 4313 Hbb-y hemoglobin Y, beta-like embryonic chain 1436823_x_at chr7 E3|7 49.95 cM 15135 13.5 9 4314 E230008O15Rik RIKEN cDNA E230008O15 gene 1439673_at --319862 13.5 9 4315 ----1446143_at ----13.5 9 4316 Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 1456985_at chr2 H3 76233 13.5 9 4317 ----1457795_at ----13.5 9 4318 5330403D14Rik RIKEN cDNA 5330403D14 gene 1453395_at --76675 13.5 9 4319 Tcrb-J T-cell receptor beta, joining region 1431653_at chr6 20.5 cM 21580 13.5 9 4320 4930524O07Rik RIKEN cDNA 4930524O07 gene 1439133_at chr9 F1 406209 13.5 9 4321 C130068B02Rik RIKEN cDNA C130068B02 gene 1440317_at --402752 13.5 9 4322 ----1440183_x_at ----13.5 9 4323 9930033D15Rik RIKEN cDNA 9930033D15 gene 1444775_at --320147 13.5 9 4324 1700029M20Rik RIKEN cDNA 1700029M20 gene 1453154_at chr4 D3 73937 13.5 9 4325 Mtmr3 myotubularin related protein 3 1443092_at chr11 A1 74302 13.5 9 4326 5530401A10Rik RIKEN cDNA 5530401A10 gene 1454477_at --71431 13.5 9 4327 Tiam1 T-cell lymphoma invasion and metastasis 1 1444373_at chr16 61.8 cM 21844 13.5 9 4328 ----1447175_at ----13.5 9 4329 ----1458592_at ----13.5 9 4330 Chmp5 chromatin modifying protein 5 1458572_at chr4 A5 76959 13.5 9 4331 Tac2 tachykinin 2 1419411_at chr10 D3 21334 13.5 9 4332 Rhoa Ras homolog gene family, member A 1443768_at chr9 F2 11848 13.5 9 4333 A330076H08Rik RIKEN cDNA A330076H08 gene 1456402_at --320026 13.5 9 4334 Slco6b1 solute carrier organic anion transporter family, member 6b1 1419535_at chr1 D 67854 13.5 9 4335 Afp alpha fetoprotein 1436879_x_at chr5 E1|5 50.0 cM 11576 13.5 9 4336 Rps9 ribosomal protein S9 1426958_at chr7 A1 76846 13.5 9 4337 Gmcl1 germ cell-less homolog 1 (Drosophila) 1438888_at chr6 D1|6 47.3 cM 23885 13.5 9 4338 LOC100046658 similar to crooked legs CG14938-PB 1457109_x_at --100046658 13.5 9 4339 Hbb-y hemoglobin Y, beta-like embryonic chain 1450621_a_at chr7 E3|7 49.95 cM 15135 13.5 9 4340 Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 1419430_at chr19 C2-C3 13082 13.5 9 4341 ----1442785_at ----13.5 9 4342 ----1439871_at ----13.5 9 4343 Mllt10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 1442070_at --17354 13.5 9 4344 Gca grancalcin 1451451_at chr2 C1.3 227960 13.5 9 4345 ----1445093_at ----13.5 9 4346 Lhx5 LIM homeobox protein 5 1420348_at chr5 F|5 64.0 cM 16873 13.5 9 4347 B830012L14Rik RIKEN cDNA B830012L14 gene 1439311_at chr12 F1 320085 13.5 9 4348 Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex 1448716_at chr11 A4|11 16.0 cM 15126 13.5 9 4349 Mpdz multiple PDZ domain protein 1441361_at chr4 C3|4 38.6 cM 17475 13.5 9 4350 Olfr112 olfactory receptor 112 1454098_at chr17 B1 258096 13.5 9 4351 BC014805 cDNA sequence BC014805 1425752_at chr19 A 236149 13.5 9 4352 ----1443744_at ----13.5 9 4353 ----1444957_at ----13.5 9 4354 AU015449 expressed sequence AU015449 1459204_at --105957 13.5 9 4355 Nav3 neuron navigator 3 1445160_at chr10 D1 260315 13.5 9 4356 ----1443675_at ----13.5 9 4357 ----1444828_at ----13.5 9 4358 ----1459338_at ----13.5 9 4359 ----1459746_at ----13.5 9 4360 AI465300 expressed sequence AI465300 1443972_at --102533 13.5 9 4361 ----1444194_at ----13.5 9 4362 Tktl1 transketolase-like 1 1449567_at chrX A7.3 83553 13.5 9 4363 ----1459049_at ----13.5 9 4364 9530068E07Rik RIKEN cDNA 9530068E07 gene 1429921_at chr11 B1.3 213673 13.5 9 4365 Gm11560 /// Gm6540 /// LOC100045189 /// LOC677262 /// Ybx1 CCAAT-binding protein /// Y box protein 1 1438064_at chr11 D /// chr17 A3.3 /// chr4 D1 100045189 /// 22608 /// 624960 /// 630936 /// 677262 13.5 9 4366 9430012M22Rik RIKEN cDNA 9430012M22 gene 1454592_at --77244 13.5 9 4367 ----1436398_at ----13.5 9 4368 ----1446296_at ----13.5 9 4369 Baz2b bromodomain adjacent to zinc finger domain, 2B 1442971_at chr2 C1.1 407823 13.5 9 4370 Odz2 odd Oz/ten-m homolog 2 (Drosophila) 1454424_at chr11 A4|11 18.0 cM 23964 13.5 9 4371 ----1459856_at ----13.5 9 4372 Mtch2 mitochondrial carrier homolog 2 (C. elegans) 1437806_x_at chr2 E1 56428 13.5 9 4373 Hbb-bh1 hemoglobin Z, beta-like embryonic chain 1437810_a_at chr7 E3|7 49.96 cM 15132 13.5 9 4374 Hbb-bh1 hemoglobin Z, beta-like embryonic chain 1437990_x_at chr7 E3|7 49.96 cM 15132 13.5 9 4375 Hbb-bh1 hemoglobin Z, beta-like embryonic chain 1450736_a_at chr7 E3|7 49.96 cM 15132 13.5 9 4376 Fxyd7 FXYD domain-containing ion transport regulator 7 1419200_at chr7 B1 57780 13.5 10 4377 Asph aspartate-beta-hydroxylase 1425275_at chr4 A1 65973 13.5 10 4378 Ambra1 autophagy/beclin 1 regulator 1 1442477_at chr2 E1 228361 13.5 10 4379 Eif2s2 eukaryotic translation initiation factor 2, subunit 2 (beta) 1441023_at chr2 H1|2 90.0 cM 67204 13.5 10 4380 ----1438245_at ----13.5 10 4381 Nono non-POU-domain-containing, octamer binding protein 1431239_at chrX D 53610 13.5 10 4382 ----1456655_at ----13.5 10 4383 6530403G13Rik RIKEN cDNA 6530403G13 gene 1429731_at --76227 13.5 10 4384 Fam13b family with sequence similarity 13, member B 1442897_at chr18 B1 225358 13.5 10 4385

PAGE 42

Prpf38b PRP38 pre-mRNA processing factor 38 (yeast) domain containing B 1455016_at chr3 G1 66921 13.5 10 4386 ----1440341_at ----13.5 10 4387 Slc16a10 solute carrier family 16 (monocarboxylic acid transporters), member 10 1453675_at chr10 B1 72472 13.5 10 4388 Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 1440609_at --26921 13.5 10 4389 ----1441547_at ----13.5 10 4390 Kcnq1ot1 KCNQ1 overlapping transcript 1 1457781_at chr7 F5|7 69.3 cM 63830 13.5 10 4391 B430203M17Rik RIKEN cDNA B430203M17 gene 1438454_at chr19 C1 320193 13.5 10 4392 Sfrs8 splicing factor, arginine/serine-rich 8 1438675_at chr5 G1.3 231769 13.5 10 4393 ----1439169_at ----13.5 10 4394 ----1456650_at ----13.5 10 4395 ----1458980_at ----13.5 10 4396 Mycbp2 MYC binding protein 2 1442858_at chr14 E2.3|14 54.58 cM 105689 13.5 10 4397 A730059M13Rik RIKEN cDNA A730059M13 gene 1443114_at --319543 13.5 10 4398 ----1458296_at ----13.5 10 4399 Trpc2 transient receptor potential cation channel, subfamily C, member 2 1430485_at chr7 F1|7 50.0 cM 22064 13.5 10 4400 Ranbp2 RAN binding protein 2 1440104_at chr10 B4|10 30.0 cM 19386 13.5 10 4401 4732423E21Rik RIKEN cDNA 4732423E21 gene 1442903_at --106967 13.5 10 4402 2610028L16Rik RIKEN cDNA 2610028L16 gene 1460474_at --76368 13.5 10 4403 Hist1h3d histone cluster 1, H3d 1453573_at --319149 13.5 10 4404 Ranbp3 RAN binding protein 3 1457711_at chr17 D 71810 13.5 10 4405 Fras1 Fraser syndrome 1 homolog (human) 1440765_at chr5 E3 231470 13.5 10 4406 ----1445350_at ----13.5 10 4407 Cblb Casitas B-lineage lymphoma b 1458469_at chr16 B5 208650 13.5 10 4408 ----1456272_at ----13.5 10 4409 ----1441789_at ----13.5 10 4410 A230071A22Rik RIKEN cDNA A230071A22 gene 1442168_at --320380 13.5 10 4411 Rai14 Retinoic acid induced 14 1444777_at chr15 A2 75646 13.5 10 4412 Thrap3 thyroid hormone receptor associated protein 3 1452125_at chr4 D2.2 230753 13.5 10 4413 Etv3 ets variant gene 3 1456358_at chr3 F1 27049 13.5 10 4414 C77673 expressed sequence C77673 1444677_at --97696 13.5 10 4415 Dpf2 D4, zinc and double PHD fingers family 2 1429903_at chr19 A|19 2.0 cM 19708 13.5 10 4416 Usp7 ubiquitin specific peptidase 7 1438249_at chr16 A1 252870 13.5 10 4417 ----1459734_at ----13.5 10 4418 ----1445020_at ----13.5 10 4419 ----1440020_at ----13.5 10 4420 ----1446245_at ----13.5 10 4421 Hmbox1 homeobox containing 1 1443020_at chr14 D1 219150 13.5 10 4422 ----1443996_at ----13.5 10 4423 Csnk2a1 casein kinase 2, alpha 1 polypeptide 1453427_at chr2 G3 12995 13.5 10 4424 ----1457175_at ----13.5 10 4425 ----1436540_at ----13.5 10 4426 Sh3rf1 SH3 domain containing ring finger 1 1442402_at chr8 B3.1 59009 13.5 10 4427 Suhw4 suppressor of hairy wing homolog 4 (Drosophila) 1457455_at chr9 D 235469 13.5 10 4428 Marveld1 MARVEL (membrane-associating) domain containing 1 1436830_at chr19 C3 277010 13.5 10 4429 Foxp1 Forkhead box P1 1438802_at chr6 E1 108655 13.5 10 4430 ----1459715_at ----13.5 10 4431 Cux1 Cut-like homeobox 1 1437431_at chr5 G2|5 78.0 cM 13047 13.5 10 4432 Matr3 matrin 3 1458508_at chr18 C|18 15.0 cM 17184 13.5 10 4433 ----1438762_at ----13.5 10 4434 Xpo4 exportin 4 1442528_at chr14 C3 57258 13.5 10 4435 ----1443613_x_at ----13.5 10 4436 ----1447147_at ----13.5 10 4437 Tbx3 T-box 3 1445757_at chr5 F|5 65.0 cM 21386 13.5 10 4438 Slbp stem-loop binding protein 1430058_at chr5 B2 20492 13.5 10 4439 D3Wsu106e DNA segment, Chr 3, Wayne State University 106, expressed 1457626_at chr3 54.2 cM 28011 13.5 10 4440 Pecr peroxisomal trans-2-enoyl-CoA reductase 1439167_at chr1 C3|1 36.1 cM 111175 13.5 10 4441 ----1445600_at ----13.5 10 4442 ----1440013_at ----13.5 10 4443 ----1456172_at ----13.5 10 4444 ----1442534_at ----13.5 10 4445 ----1443337_at ----13.5 10 4446 ----1441437_at ----13.5 10 4447 Sfrs11 splicing factor, arginine/serine-rich 11 1430077_at chr3 H4 69207 13.5 10 4448 ----1457842_at ----13.5 10 4449 Tmem57 transmembrane protein 57 1430418_at chr4 D3|4 65.69 cM 66146 13.5 10 4450 Rac1 RAS-related C3 botulinum substrate 1 1437674_at chr5 G2|5 82.0 cM 19353 13.5 10 4451 ----1439298_at ----13.5 10 4452 Ube3a ubiquitin protein ligase E3A 1445727_at chr7 C|7 28.65 cM 22215 13.5 10 4453 Ccdc58 coiled-coil domain containing 58 1440260_at chr16 B3 381045 13.5 10 4454 ----1446955_at ----13.5 10 4455 D15Wsu126e DNA segment, Chr 15, Wayne State University 126, expressed 1446972_at chr15 30.0 cM 28112 13.5 10 4456 Med15 mediator complex subunit 15 1441617_at chr16 A3|16 9.9 cM 94112 13.5 10 4457 Rbm39 RNA binding motif protein 39 1442744_at chr2 H1 170791 13.5 10 4458 2410022L05Rik RIKEN cDNA 2410022L05 gene 1420114_s_at chr8 A1.1 66423 13.5 10 4459 Zcchc7 zinc finger, CCHC domain containing 7 1438580_at chr4 B1 319885 13.5 10 4460 AI451458 expressed sequence AI451458 1442122_at --102916 13.5 10 4461 ----1438398_at ----13.5 10 4462 AU022084 expressed sequence AU022084 1443442_at --101250 13.5 10 4463 Ddx42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 1443719_x_at chr11 E1 72047 13.5 10 4464 Atxn2 /// LOC100047323 ataxin 2 /// similar to ataxin 2 1459363_at chr5 F 100047323 /// 20239 13.5 10 4465 Htt huntingtin 1456667_at chr5 B2|5 20.0 cM 15194 13.5 10 4466 ----1431996_at ----13.5 10 4467 ----1458874_at ----13.5 10 4468 2810404I24Rik RIKEN cDNA 2810404I24 gene 1432923_at --76949 13.5 10 4469 ----1443533_at ----13.5 10 4470 2310029O18Rik RIKEN cDNA 2310029O18 gene 1454031_at --76946 13.5 10 4471 Nucks1 Nuclear casein kinase and cyclin-dependent kinase substrate 1 1444953_at chr1 E4 98415 13.5 10 4472 ----1458241_at ----13.5 10 4473 ----1443603_at ----13.5 10 4474 ----1456947_at ----13.5 10 4475 Gsk3b glycogen synthase kinase 3 beta 1439931_at chr16 B4 56637 13.5 10 4476 Dctn4 dynactin 4 1458596_at chr18 D2 67665 13.5 10 4477 Igsf9 immunoglobulin superfamily, member 9 1441420_at chr1 H3|1 94.0 cM 93842 13.5 10 4478 D11Ertd326e DNA segment, Chr 11, ERATO Doi 326, expressed 1420173_at chr11 11.0 cM 52574 13.5 10 4479 5830469G19Rik RIKEN cDNA 5830469G19 gene 1430089_at --76093 13.5 10 4480 Neo1 neogenin 1444295_at chr9 B 18007 13.5 10 4481 ----1457402_at ----13.5 10 4482 ----1446048_at ----13.5 10 4483 Ces8 carboxylesterase 8 (putative) 1451615_at chr8 D3 234677 13.5 10 4484 2310010M20Rik RIKEN cDNA 2310010M20 gene 1432107_at chr16 B2 69576 13.5 10 4485 ----1440841_at ----13.5 10 4486 Fcho2 FCH domain only 2 1442453_at chr13 D1 218503 13.5 10 4487 Ahctf1 AT hook containing transcription factor 1 1438816_at chr1 H4|1 102.0 cM 226747 13.5 10 4488 ----1447094_at ----13.5 10 4489 D330022H12Rik RIKEN cDNA D330022H12 gene 1430251_at --77095 13.5 10 4490 4933404G15Rik RIKEN cDNA 4933404G15 gene 1431509_at chr16 A3 74066 13.5 10 4491 ----1439097_at ----13.5 10 4492

PAGE 43

----1442569_at ----13.5 10 4493 Ptk2 PTK2 protein tyrosine kinase 2 1443384_at chr15 D3|15 42.0 cM 14083 13.5 10 4494 C530014P21Rik RIKEN cDNA C530014P21 gene 1447510_at --399604 13.5 10 4495 ----1441677_at ----13.5 10 4496 Hmga2 high mobility group AT-hook 2 1446196_at chr10 D2|10 67.5 cM 15364 13.5 10 4497 ----1446289_at ----13.5 10 4498 ----1458684_at ----13.5 10 4499 Lix1 limb expression 1 homolog (chicken) 1421180_at chr17 A3.1 66643 13.5 10 4500 Chd9 chromodomain helicase DNA binding protein 9 1458078_at chr8 C5 109151 13.5 10 4501 ----1441324_at ----13.5 10 4502 Mbtd1 Mbt domain containing 1 1443862_at chr11 D 103537 13.5 10 4503 ----1427600_at ----13.5 10 4504 ----1458077_at ----13.5 10 4505 Usp4 ubiquitin specific peptidase 4 (proto-oncogene) 1442319_at chr9 F2|9 60.0 cM 22258 13.5 10 4506 Myst2 MYST histone acetyltransferase 2 1447631_at chr11 D 217127 13.5 10 4507 9530086O07Rik RIKEN cDNA 9530086O07 gene 1430392_at --78741 13.5 10 4508 LOC667118 zinc finger, BED domain containing 4 pseudogene 1441112_at chr1 E4 667118 13.5 10 4509 ----1436933_at ----13.5 10 4510 ----1437916_at ----13.5 10 4511 Clcn7 chloride channel 7 1425821_at chr17 A3.3|17 10.0 cM 26373 13.5 10 4512 2610319H10Rik RIKEN cDNA 2610319H10 gene 1438429_at --72505 13.5 10 4513 ----1440011_at ----13.5 10 4514 D2Ertd173e DNA segment, Chr 2, ERATO Doi 173, expressed 1444330_at chr2 103.0 cM 51864 13.5 10 4515 Usp47 ubiquitin specific peptidase 47 1457454_at chr7 F2 74996 13.5 10 4516 ----1445148_at ----13.5 10 4517 ----1446182_at ----13.5 10 4518 6030490B17Rik RIKEN cDNA 6030490B17 gene 1440163_at --77715 13.5 10 4519 ----1446490_at ----13.5 10 4520 Magi1 Membrane associated guanylate kinase, WW and PDZ domain containing 1 1458240_at chr6 D3 14924 13.5 10 4521 ----1441771_at ----13.5 10 4522 Tcf12 transcription factor 12 1439619_at chr9 D|9 42.0 cM 21406 13.5 10 4523 ----1445804_at ----13.5 10 4524 Fam48a family with sequence similarity 48, member A 1443000_at chr3 D 56790 13.5 10 4525 ----1444620_at ----13.5 10 4526 ----1458637_x_at ----13.5 10 4527 ----1440121_at ----13.5 10 4528 ----1459289_at ----13.5 10 4529 ----1440701_at ----13.5 10 4530 Pigs phosphatidylinositol glycan anchor biosynthesis, class S 1457640_x_at chr11 B5 276846 13.5 10 4531 2610036L11Rik RIKEN cDNA 2610036L11 gene 1429156_at chr10 A4 66311 13.5 10 4532 ----1444126_at ----13.5 10 4533 Sfrs12 splicing factor, arginine/serine-rich 12 1458056_at chr13 D1 218543 13.5 10 4534 Aff2 AF4/FMR2 family, member 2 1458014_at chrX A5 14266 13.5 10 4535 6430537K16Rik RIKEN cDNA 6430537K16 gene 1438878_at --320480 13.5 10 4536 ----1441415_at ----13.5 10 4537 Gm12816 /// Gm4959 /// Gm5850 /// Gm5879 /// Gm6035 /// Rpl3 predicted gene 12816 1438527_at chr13 D2.2 /// chr15 E1 /// chr3 F1 /// chr4 D1 /// chr5 A1 242809 /// 27367 /// 433745 /// 545543 /// 545864 /// 547402 13.5 10 4538 Zfr Zinc finger RNA binding protein 1442311_at chr15 A 22763 13.5 10 4539 Tcf12 Transcription factor 12 1439209_at chr9 D|9 42.0 cM 21406 13.5 10 4540 ----1441253_at ----13.5 10 4541 9430047G12Rik RIKEN cDNA 9430047G12 gene 1458892_at --102344 13.5 10 4542 Mycbp2 MYC binding protein 2 1447150_at chr14 E2.3|14 54.58 cM 105689 13.5 10 4543 ----1457637_at ----13.5 10 4544 Dnm3os dynamin 3, opposite strand 1452382_at chr1 H2.1 474332 13.5 10 4545 Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 1421280_at chr11 A5|11 19.0 cM 14394 13.5 10 4546 Mef2a Myocyte enhancer factor 2A 1442623_at chr7 C|7 33.0 cM 17258 13.5 10 4547 9430019C24Rik RIKEN cDNA 9430019C24 gene 1453458_at chr8 B1.1 77279 13.5 10 4548 1110007A13Rik RIKEN cDNA 1110007A13 gene 1439126_at chr7 F3 210711 13.5 10 4549 ----1439970_at ----13.5 10 4550 March7 membrane-associated ring finger (C3HC4) 7 1458690_at chr2 C3 57438 13.5 10 4551 A130022J21Rik RIKEN cDNA A130022J21 gene 1444764_at --320617 13.5 10 4552 ----1457343_at ----13.5 10 4553 C130075A20Rik RIKEN cDNA C130075A20 gene 1442845_at --320395 13.5 10 4554 Arid3b AT rich interactive domain 3B (BRIGHT-like) 1423526_at chr9 C 56380 13.5 10 4555 B3gat3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) 1431219_at chr19 A 72727 13.5 10 4556 ----1443394_at ----13.5 10 4557 5230400M03Rik RIKEN cDNA 5230400M03 gene 1437493_at chr2 C1.1 329406 13.5 10 4558 ----1446924_at ----13.5 10 4559 ----1443161_at ----13.5 10 4560 ----1444459_at ----13.5 10 4561 Ube2w ubiquitin-conjugating enzyme E2W (putative) 1443188_at chr1 A3 66799 13.5 10 4562 C77631 expressed sequence C77631 1445195_at --97357 13.5 10 4563 B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 1425316_at chr9 A4 76898 13.5 10 4564 ----1458739_at ----13.5 10 4565 ----1442617_at ----13.5 10 4566 Dtl denticleless homolog (Drosophila) 1453753_at chr1 H6 76843 13.5 10 4567 Pogz pogo transposable element with ZNF domain 1457748_at chr3 F2.1 229584 13.5 10 4568 Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 1423226_at chr19 B|19 4.0 cM 12482 13.5 10 4569 Ankrd17 ankyrin repeat domain 17 1445826_at --81702 13.5 10 4570 Tatdn1 TatD DNase domain containing 1 1438513_at chr15 D1 69694 13.5 10 4571 Arid5b AT rich interactive domain 5B (MRF1-like) 1458238_at chr10 B5.1 71371 13.5 10 4572 Trim31 tripartite motif-containing 31 1425308_at chr17 B1 224762 13.5 10 4573 ----1443363_at ----13.5 10 4574 6720477C19Rik RIKEN cDNA 6720477C19 gene 1433184_at --77731 13.5 10 4575 Arpc2 Actin related protein 2/3 complex, subunit 2 1442295_at chr1 C3|1 40.3 cM 76709 13.5 10 4576 Rps6ka2 ribosomal protein S6 kinase, polypeptide 2 1441311_at chr17 F4|17 3.65 cM 20112 13.5 10 4577 ----1439174_at ----13.5 10 4578 ----1438929_at ----13.5 10 4579 Ccdc76 coiled-coil domain containing 76 1443323_at chr3 G1 229780 13.5 10 4580 9030607L02Rik RIKEN cDNA 9030607L02 gene 1432978_at --75754 13.5 10 4581 Ulk2 Unc-51 like kinase 2 (C. elegans) 1439591_at chr11 B2 29869 13.5 10 4582 Sympk Symplekin 1459000_at chr7 A3 68188 13.5 10 4583 Cbara1 calcium binding atopy-related autoantigen 1 1443340_at chr10 B4 216001 13.5 10 4584 ----1445900_at ----13.5 10 4585 F830028O17Rik RIKEN cDNA F830028O17 gene 1436457_at --320071 13.5 10 4586 Trpv1 transient receptor potential cation channel, subfamily V, member 1 1443392_at chr11 B3 193034 13.5 10 4587 ----1459517_at ----13.5 10 4588 ----1458147_at ----13.5 10 4589 9430047L24Rik RIKEN cDNA 9430047L24 gene 1458811_at --320850 13.5 10 4590 ----1459485_at ----13.5 10 4591 ----1441373_at ----13.5 10 4592 Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 1450404_at chr18 B2|18 18.0 cM 20522 13.5 10 4593 Pctk1 PCTAIRE-motif protein kinase 1 1443296_at chrX A1.3|X 5.7 cM 18555 13.5 10 4594 Nlrp4a NLR family, pyrin domain containing 4A 1438077_at chr7 A3 243880 13.5 10 4595 ----1456661_at ----13.5 10 4596 AI225934 expressed sequence AI225934 1441001_at --98884 13.5 10 4597 ----1440552_at ----13.5 10 4598 ----1441375_at ----13.5 10 4599

PAGE 44

D930015E06Rik RIKEN cDNA D930015E06 gene 1440625_at chr3 F1 229473 13.5 10 4600 ----1459707_at ----13.5 10 4601 Wdr75 WD repeat domain 75 1442296_at chr1 C1 73674 13.5 10 4602 Gprin1 G protein-regulated inducer of neurite outgrowth 1 1424137_at chr13 B2 26913 13.5 10 4603 Pebp4 phosphatidylethanolamine binding protein 4 1430706_at chr14 D2 73523 13.5 10 4604 Adamts18 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 1446247_at chr8 E1 208936 13.5 10 4605 ----1438821_at ----13.5 10 4606 Nudt5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 1430341_at chr2 A1 53893 13.5 10 4607 ----1442775_at ----13.5 10 4608 ----1446839_at ----13.5 10 4609 Vcan versican 1433043_at chr13 C3|13 55.0 cM 13003 13.5 10 4610 Atxn2 Ataxin 2 1443516_at chr5 F 20239 13.5 10 4611 Fnbp4 formin binding protein 4 1438700_at chr2 E1 55935 13.5 10 4612 ----1438871_at ----13.5 10 4613 ----1442067_at ----13.5 10 4614 ----1459473_at ----13.5 10 4615 ----1446521_at ----13.5 10 4616 ----1458920_at ----13.5 10 4617 Itch itchy, E3 ubiquitin protein ligase 1459332_at chr2 H1|2 89.0 cM 16396 13.5 10 4618 Gabrp gamma-aminobutyric acid (GABA) A receptor, pi 1424647_at chr11 A4 216643 13.5 10 4619 Birc6 baculoviral IAP repeat-containing 6 1437789_at --12211 13.5 10 4620 ----1440092_at ----13.5 10 4621 2600002B07Rik RIKEN cDNA 2600002B07 gene 1429967_at --72343 13.5 10 4622 Gm7536 Predicted gene 7536 1437729_at chr3 A3 665189 13.5 10 4623 ----1442239_at ----13.5 10 4624 ----1447270_at ----13.5 10 4625 Gnb1 guanine nucleotide binding protein (G protein), beta 1 1425908_at chr4 E2|4 79.4 cM 14688 13.5 10 4626 ----1438894_at ----13.5 10 4627 Neil3 nei like 3 (E. coli) 1440633_at chr8 B1.3 234258 13.5 10 4628 D15Ertd529e DNA segment, Chr 15, ERATO Doi 529, expressed 1444846_at chr15 6.7 cM 52510 13.5 10 4629 ----1456965_at ----13.5 10 4630 Stambpl1 STAM binding protein like 1 1430367_at chr19 C1 76630 13.5 10 4631 Itgav integrin alpha V 1432678_at chr2 D|2 46.0 cM 16410 13.5 10 4632 1700081L11Rik RIKEN cDNA 1700081L11 gene 1457062_at chr11 E1 76719 13.5 10 4633 ----1437599_at ----13.5 10 4634 Rif1 Rap1 interacting factor 1 homolog (yeast) 1438516_at chr2 C1.1|2 31.0 cM 51869 13.5 10 4635 Dzip1 DAZ interacting protein 1 1443772_at chr14 E4 66573 13.5 10 4636 Topbp1 topoisomerase (DNA) II binding protein 1 1458480_at chr9 F1 235559 13.5 10 4637 Tyms Thymidylate synthase 1438690_at chr5 B1|5 18.2 cM 22171 13.5 10 4638 Myo1b myosin IB 1458007_at chr1 C1.1|1 24.8 cM 17912 13.5 10 4639 ----1440012_at ----13.5 10 4640 A130004G07Rik RIKEN cDNA A130004G07 gene 1440430_at chr2 E3 320687 13.5 10 4641 ----1456906_at ----13.5 10 4642 ----1459010_at ----13.5 10 4643 Trav17 T cell receptor alpha variable 17 1443140_at chr14 C2 627777 13.5 10 4644 Acan aggrecan 1449827_at chr7 D3|7 39.0 cM 11595 13.5 10 4645 AA409368 expressed sequence AA409368 1457466_at --98783 13.5 10 4646 Pi4ka phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 1457379_at chr16 A3 224020 13.5 10 4647 ----1427437_at ----13.5 10 4648 Fancl Fanconi anemia, complementation group L 1432337_at chr11 A2-A3 67030 13.5 10 4649 Fibp fibroblast growth factor (acidic) intracellular binding protein 1430171_at chr19 A 58249 13.5 10 4650 ----1459011_at ----13.5 10 4651 2410042D21Rik RIKEN cDNA 2410042D21 gene 1443314_at chr2 E4 72425 13.5 10 4652 ----1444541_at ----13.5 10 4653 Tle3 transducin-like enhancer of split 3, homolog of Drosophila E(spl) 1458512_at --21887 13.5 10 4654 2210017G18Rik RIKEN cDNA 2210017G18 gene 1433209_at --70386 13.5 10 4655 ----1457184_at ----13.5 10 4656 Mrpl11 mitochondrial ribosomal protein L11 1438080_at chr19 A 66419 13.5 10 4657 ----1446172_at ----13.5 10 4658 ----1446504_at ----13.5 10 4659 ----1446167_at ----13.5 10 4660 ----1457173_at ----13.5 10 4661 E130112M24Rik /// Six3 RIKEN cDNA E130112M24 gene /// sine oculis-related homeobox 3 homolog (Drosophila) 1427523_at chr17 E4|17 45.5 cM 20473 /// 77999 13.5 10 4662 ----1441882_at ----13.5 10 4663 ----1459968_at ----13.5 10 4664 ----1439643_at ----13.5 10 4665 ----1439813_at ----13.5 10 4666 9230110I02Rik RIKEN cDNA 9230110I02 gene 1460499_at chr3 F2.1 77698 13.5 10 4667 9530029O12Rik RIKEN cDNA 9530029O12 gene 1457161_at --399629 13.5 10 4668 Birc6 baculoviral IAP repeat-containing 6 1442959_at --12211 13.5 10 4669 2310009B15Rik RIKEN cDNA 2310009B15 gene 1455761_at chr1 F 69549 13.5 10 4670 ----1445317_at ----13.5 10 4671 Fam43b family with sequence similarity 43, member B 1435063_at chr4 D3 625638 13.5 10 4672 ----1439572_at ----13.5 10 4673 D13Ertd787e DNA segment, Chr 13, ERATO Doi 787, expressed 1457304_at chr13 29.0 cM 52680 13.5 10 4674 D230044B12Rik RIKEN cDNA D230044B12 gene 1441558_at --399635 13.5 10 4675 ----1458042_at ----13.5 10 4676 ----1444269_at ----13.5 10 4677 ----1444788_x_at ----13.5 10 4678 ----1444825_at ----13.5 10 4679 ----1442078_at ----13.5 10 4680 Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 1446374_at chr8 A1.1 234094 13.5 10 4681 Tle4 transducin-like enhancer of split 4, homolog of Drosophila E(spl) 1430384_at chr19 A|19 7.0 cM 21888 13.5 10 4682 LOC100046241 /// Tlk1 similar to tousled-like kinase 1 /// tousled-like kinase 1 1460002_at chr2 C2 100046241 /// 228012 13.5 10 4683 ----1441635_at ----13.5 10 4684 Nasp nuclear autoantigenic sperm protein (histone-binding) 1444583_at chr4 56.5 cM 50927 13.5 10 4685 D130023J23Rik RIKEN cDNA D130023J23 gene 1440985_at --319769 13.5 10 4686 ----1444937_at ----13.5 10 4687 ----1444920_at ----13.5 10 4688 8430406H22Rik RIKEN cDNA 8430406H22 gene 1431158_at --71495 13.5 10 4689 Napg N-ethylmaleimide sensitive fusion protein attachment protein gamma 1443366_at chr18 D3 108123 13.5 10 4690 Gnb2l1 Guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 1440120_at chr11 B1.2 14694 13.5 10 4691 Hoxa10 Homeo box A10 1446408_at chr6 B3|6 26.33 cM 15395 13.5 10 4692 Top1 topoisomerase (DNA) I 1457573_at chr2 H2-3|2 92.0 cM 21969 13.5 10 4693 Pcdhg@ Protocadherin gamma cluster 1458721_at chr18 B3 192682 13.5 10 4694 Cluster Number and Cluster Order corresponds to Figure 3b, female at E13.5 versus female at E15.5 dendrogram.





PAGE 1

Gene Symbol Gene Title Probe Set ID Entrez Gene Gender Enriched Casp6 caspase 6 1415995_at 12368 F Psrc1 proline/serine-rich coiled-coil 1 1417323_at 56742 F 5730494M16Rik RIKEN cDNA 5730494M16 gene 1428189_at 66648 F Polr2e polymerase (RNA) II (DNA directed) polypeptide E 1417138_s_at 66420 F Snrpb small nuclear ribonucleoprotein B 1419260_a_at 20638 F Ctsz cathepsin Z 1417870_x_at 64138 F Dgcr8 DiGeorge syndrome critical region gene 8 1435439_at 94223 F Grem2 gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis) 1418492_at 23893 F Lsamp limbic system-associated membrane protein 1435895_at 268890 F Lix1l Lix1-like 1436546_at 280411 F LOC100046963 /// Pgm5 similar to phosphoglucomutase 5 /// phosphoglucomutase 5 1437871_at 100046963 /// 226041 F Cryab crystallin, alpha B 1416455_a_at 12955 F Dpp4 dipeptidylpeptidase 4 1416697_at 13482 F Ndst3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1453777_a_at 83398 F ----1447996_at --F Serpinb3b /// Serpinb3c serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B /// serine (or cysteine) peptidase inhibitor, clade B, member 3C 1422940_x_at 381286 /// 383548 F ----1445020_at --F Tprg transformation related protein 63 regulated 1430114_at 71338 F Rab40b Rab40b, member RAS oncogene family 1425756_at 217371 F ----1446181_at --F Ube3a ubiquitin protein ligase E3A 1416682_at 22215 M Srd5a3 steroid 5 alpha-reductase 3 1456691_s_at 57357 M Slc35a2 solute carrier family 35 (UDP-galactose transporter), member A2 1457024_x_at 22232 M Atp13a1 ATPase type 13A1 1417475_at 170759 M Usp14 ubiquitin specific peptidase 14 1439201_at 59025 M Wdr26 WD repeat domain 26 1451188_at 226757 M Rrm2b ribonucleotide reductase M2 B (TP53 inducible) 1433773_at 382985 M Slc25a46 solute carrier family 25, member 46 1418134_at 67453 M Cbx6 chromobox homolog 6 1424407_s_at 494448 M Chm choroidermia 1439824_at 12662 M 2610507B11Rik RIKEN cDNA 2610507B11 gene 1426820_at 72503 M Mbtps1 membrane-bound transcription factor peptidase, site 1 1448240_at 56453 M LOC640441 /// Thbs1 similar to thrombospondin 1 /// thrombospondin 1 1421811_at 21825 /// 640441 M ----1437375_at --M Nr2c1 nuclear receptor subfamily 2, group C, member 1 1446194_at 22025 M Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 1438856_x_at 20724 M Nipal1 NIPA-like domain containing 1 1456321_at 70701 M Mgst2 microsomal glutathione S-transferase 2 1452592_at 211666 M D4Ertd58e DNA segment, Chr 4, ERATO Doi 58, expressed 1448089_at 52054 M Targets of the androgen receptor at E13.5.