Title: Adaptation of membrane-bound enzymes to ethanol
Full Citation
Permanent Link: http://ufdc.ufl.edu/UF00098910/00001
 Material Information
Title: Adaptation of membrane-bound enzymes to ethanol
Physical Description: vii, 58 leaves : ill. ; 28 cm.
Language: English
Creator: Dickens, Benjamin Fisher, 1951- ( Dissertant )
Ingram, Lonnie O. ( Thesis advisor )
Hoffman, Edward M. ( Reviewer )
Allen, Charles M. ( Reviewer )
Sisler, H. H. ( Degree grantor )
Publisher: University of Florida
Place of Publication: Gainesville, Fla.
Publication Date: 1978
Copyright Date: 1978
Subjects / Keywords: Lipid membranes   ( lcsh )
Microbiology and Cell Science thesis Ph. D
Alcohol -- Physiological effect   ( lcsh )
Dissertations, Academic -- Microbiology and Cell Science -- UF
Genre: bibliography   ( marcgt )
non-fiction   ( marcgt )
Abstract: Previous studies have shown that the proportion of unsaturated fatty acids increases in _E^he£ichia_coli_during growth in the presence of ethanol. These lipid changes presumably represent an adaptive response to compensate for the direct physical effect of ethanol on the membrane lipid bilayer. The effects of growth in the presence of ethanol on two membrane-bound enzymes, the lactose permease and adenosine triphosphatase, were investigated. All but one of the properties of these membrane-bound enzymes, the activity of membranebound ATPase with Ca as a cofactor, were found to adapt to the presences of ethanol. The role of new protein synthesis and the ethanol-induced changes in the bulk lipid composition in the adaptation of membrane-bound enzymes to ethanol was also investigated, Results of these investigations led to a model proposing that ethanol's effect on both membrane-bound enzymes and the adaptation of these enzymes to ethanol is mediated through the enzymes annular lipids.
Statement of Responsibility: by Benjamin Fisher Dickens, Jr.
Thesis: Thesis--University of Florida.
Bibliography: Bibliography: leaves 54-57.
General Note: Typescript.
General Note: Vita.
 Record Information
Bibliographic ID: UF00098910
Volume ID: VID00001
Source Institution: University of Florida
Holding Location: University of Florida
Rights Management: All rights reserved by the source institution and holding location.
Resource Identifier: alephbibnum - 000081135
oclc - 05086234
notis - AAJ6453


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