Veterinary Science Florida Agricultural
Mimeo Report VY66-3 Experiment S
June 1966 IHUMAE eiBi a
CURRENT RESEARCH ON ANIMAL DI ASES AUG 4 1972
George T. Edds
I.F.A.S. Univ. of Florida
In the Fall of 1965, a Gilchrist county bee- producer reported
losses of 8-10 percent of his herd from a "downer-cow" problem. The
disease was characterized by loss of appetite, weakness, diarrhea.
Some animals showed red urine. Several of the animals died within
24 hours after they had gone down. Other animals in the herd showed
some incoordination-if they were forced to move rapidly or very
far, they would go down.
A graduate veterinarina, working on his Master of Science degree
in Veterinary Science under an NIH grant on Toxicology, chose this
problem for his thesis research. Arrangements were made with the
county agent, local veterinarian and farmer to secure a quantity of
the Cassia plant for feeding trials in rabbits and six calves.
The symptoms did not develop until 24-36 hours prior to death.
These included complete loss of appetite, lethargy, and ataxia.
Severe diarrhea developed in one of the calves; in the others, a
slight diarrhea became severe by the third to fourth day and contin-
ued until death occurred. Certain of the calves showed muscle tremors,
particularly of the rear limbs. The calves went down in sternal
recumbency about 12 hours prior to death.
This study indicates that the Cassia species common to Florida
is capable of producing death in rabbits and cattle. Should this
syndrome appear in your herd, you and your local veterinarian should
consider this plant as a probable etiological agent.
The infective, pathogenic vibrio, Vibrio fetus, venerealis
has been isolated from approximately 12 percent of reproductive tracts
of beef cows going to slaughter. Various other infectious agents
including streptococci, corynebacteria, coliforms and other gram-
negative bacteria have been identified. Various pathological
conditions were observed in the tracts, ranging from mild cervicitis
to severe metritis. Controlled vaccine studies are to be run to
determine whether this apparent contributory cause of infertility in
beef cows can be controlled.
Infectious keratoconjunctivitis or pink-eye continues to be a
serious problem in certain beef cattle herds. Research on possible
vaccination programs to reduce the incidence and severity of the
lesions are underway. Some work suggests that vaccination with an
infectious bovine rhinotracheitis agent will decrease the likelihood
of outbreaks. Work with a new specific viral agent isolated by
research workers at the Anderson Foundation in Houston shows it, too,
may be involved in pink-eye. One of the earlier microorganisms
isolated and believed to be responsible for pink-eye, Moraxella bovis,
has been frequently found in outbreaks here in Florida.-~"ThTs-Tar,
treatment of both eyes of all cattle on the premises, has markedly
reduced the incidence in beginning outbreaks.
The Committee on Anaplasmosis of the USLSA is planning a
thorough review of the current information on this important disease.
This will include studies on the nature of the infectious agent, the
relationship between this and other blood parasites like piroplasmosis
in horses, the response expected in vaccinates from the commercial
vaccine "Anaplaz" and their resistance to field challenge and
persistence of immunity. At present, valuable bulls or cows to be
imported onto premises where the cattle are known to be infected
carriers, are so vaccinated to reduce their possible loss at the time
of exposure. Further research is continuing on drugs which can be
used to prevent infection or treat acute outbreaks. The AEC contract
to support basic research and the possible production of an X-ray
attenuated vaccine is enabling us to continue our research on this
important disease problem.
PROGRAMMED ANIMAL HEALTH FOR A COW-CALF OPERATION
Dr. Melvin Horning, Practitioner, Alturas, California
1. Establish Need for Program
A. Larger Units-Investors unfamiliar with business.
B. Diseases more difficult to differentiate.
2. Large animal practice-Specialization required.
A. Beef Cattle
3. Variation from area to area-separate set of circumstances
4. How to sell program-Prove economic advantages.
A. Bankers support-Fertilize pastures; pregn.
tests-etc. to get loan.
B. Continuous process of advising new mgmt.
C. Records to be kept by Veterinarian-
deficiencies in soil.
5. After calves weaned
A. Start preg. diagnosis; check for signs of
cancer-eye; and teeth & condition.
B. Vaccinate for leptospirosis and vibriosis.
C. If too many unsettled-run vaginal swabs and
serology to see what the cause may be.
D. Do fecal sampling regularly-especially in
PROGRAMMED FEEDLOT HEALTH PRACTICE
Dc. Shideler Equine, Dairy, Beef-lot operations
1. An opportunity to practice preventive medicine.
Weekly (or regular) visits keep one informed of
the feedlot status and allows opportunity to plan
2. The advantages of permitting one to utilize his
veterinary medical training for diagnosis, laboratory
procedures, and various testing methods at our disposal.
3. This gives the feedlot an opportunity to prepare for
your visit, again saving you time.
4. The priviledge of being a part of a functional,
What does the Veterinarian have to offer a feedlot operator?
A. Clinical diagnostic ability.
B. Laboratory diagnosis and interpretations.
C. Preventive medicine.
2. Skills our ability to do various techniques in an
efficient time-saving manner.
A. The administration of drugs.
B. Various vaccinations.
C. Post mortem examinations.
What can the Veterinarian do to increase his value in the
1. Be prompt with each appointment.
3. Show a desire to work.
4. Develop and improve your ability and skill.
5. Exert every effort to make a complete and accurate
diagnosis each time a problem is presented.
6. Have a weekly written report of inspections and
7, Training Lay Personnel.
How may the Veterinarian supply drugs?
1. A Veterinarian, by initial agreement, may supply all
drugs used, at invoice price plus 10%.
2. How are the drugs used?
A. Under the Veterianarian's directions, when not
specifically by him. Follow up treatments of
individuals can easily be done by cowboys properly
What are the feedlot's obligation to the Veterinarian?
1. To provide proper working facilities.
2. To have available the operator or suitable attendant
to company the Veterinarian on inspection trips.
3. Be ready and properly prepared for your scheduled visits.
Have cattle ready to work or available for inspection.
4. By initial agreement, payment of account by the 10th
day of each month.
5. Identify each lot of cattle with a member brand-may have
to STOP buying cattle from one source.