Citation
Summer Focus on the Physical Sciences and Quantitative Research: What Are the Effects of Long-Term NSAID Therapy on Cognition in Older Adults? A Literature Review

Material Information

Title:
Summer Focus on the Physical Sciences and Quantitative Research: What Are the Effects of Long-Term NSAID Therapy on Cognition in Older Adults? A Literature Review
Series Title:
Journal of Undergraduate Research
Creator:
Snigurska, Urszula A.
Horgas, Ann L.
Place of Publication:
Gainesville, Fla.
Publisher:
University of Florida
Publication Date:
Language:
English

Subjects

Subjects / Keywords:
NSAIDs
aspirin
dementia
older adults
Genre:
serial ( sobekcm )

Notes

Abstract:
Dementia is a major neurocognitive disorder characterized by deterioration in memory, thinking, and behavior, which results in the inability to perform activities of daily living. Alzheimer’s disease is the most common type of dementia. Preventative approaches against neurocognitive disease in older adults described in the literature have focused on the use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs). The CINAHL and PubMed databases were searched for previous studies, of which sixteen were analyzed, but these studies showed no strong evidence that NSAIDs have an effect on slowing the progression of cognitive decline in community-dwelling older adults. The results on the effects of NSAIDs on cognitive function are mixed. Based on the current evidence, there is no medical recommendation to initiate NSAID therapy in order to prevent cognitive decline.

Record Information

Source Institution:
University of Florida
Holding Location:
University of Florida
Rights Management:
Copyright by Creator or Publisher. Permission granted to University of Florida to digitize and display this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.

Downloads

This item is only available as the following downloads:


Full Text

PAGE 1

College of Nursing, University of Florida Keywords

PAGE 2

Effects of NSAIDs on Cognitive Function

PAGE 4

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 11 Neurology Frontiers in Aging Neuroscience, 2 The Lancet: Neurology Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 7 Annals of Epidemiology, 7

PAGE 5

Cochrane Database of Systematic Reviews, 2012 Neurobiology of Aging British Medical Journal, 334 Drug Safety, 19 International Journal of Geriatric Psychiatry, 27 Pain Medicine, 12 Archives of Neurology, 65 Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 9 British Medical Journal, 337 The Cochrane Database of Systematic Reviews Journal of the American Geriaritcs Society American Journal of Epidemiology, 143 Neurology India, 64 Journal of the Americ an Geriaritcs Society Alzheimer Disease and Asso ciated Disorders, 30 International Journal of AlzheimerÂ’s Disease

PAGE 6

substantial some substantial some

PAGE 7

Notes American Journal of Epidemiology, 143 The Cochrane Database of Systematic Reviews British Medical Journal, 334 British Medical Journal, 337

PAGE 9

Notes Journal of the American Geriaritcs Society Neurobiology of Aging Neurology Journal of the American Geriaritcs Society Frontiers in Aging Neuroscience, 2

PAGE 10

Alzheimer Disease and Associated Disorders, 30 not substantial consistent deleterious

PAGE 11

deleterious

PAGE 12

Notes

PAGE 13

Annals of Epidemiology 7 Archives of Neurology, 65 Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 7 Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 9 Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 11 International Journal of Geriatric Psychiatry, 27