Title: Continuum newsletter
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Permanent Link: http://ufdc.ufl.edu/UF00091266/00006
 Material Information
Title: Continuum newsletter
Physical Description: Serial
Language: English
Creator: Institute on Aging, University of Florida
Publisher: Institute on Aging, University of Florida
Place of Publication: Gainesville, Fla.
Publication Date: Spring 2010
Copyright Date: 2010
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Bibliographic ID: UF00091266
Volume ID: VID00006
Source Institution: University of Florida
Holding Location: University of Florida
Rights Management: All rights reserved by the source institution and holding location.

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UFFLIS A InstitteIon ging V


UF Seeks Older Adults for LIFE Study
Lifestyle Interventions and Independence For Elders (LIFE) Study will
Determine Whether Exercise Prevents Mobility Disability
The University of Florida is seeking older adults between the ages of
70 and 89 to take part in a lifestyle interventions study that will deter-
mine whether exercise or health education can prevent or delay major
movement disability in older adults. Field sites
are in both Gainesville and Jacksonville; the
trial is currently being conducted at a total of
eight institutions around the country.
Called the Lifestyle Interventions and
Independence for Elders (LIFE) Study, this
6-year study is a phase 3 randomized controll-
ed trial of 1,600 sedentary older adults who
are at risk of mobility disability. The LIFE
Study is comparing the long-term effectiveness
Continued on page 2


The IOA Receives Award for New Building


Following a highly competitive peer review process, the University of
Florida's Institute on Aging (IOA) has been awarded a grant under the
American Recovery and Reinvestment Act to build a complex in-
tended to facilitate participation of older adults in clinical trials and promote
cooperation among existing research centers, including: the Claude D. Pep-
per Older Americans Independence Center, the Clinical and Translational
Science Institute and the recently established Cognitive Aging and Memory
Clinical Translational Research Program.
Continued on page 2


Dear friends of the IOA,
It is our great pleasure to
announce that Dr. Susan Nayfield has
recentlyjoined our Department and
Institute as Associate Professor and
Division Chief of the Clinical Research
Division and Acting Chief of the
Geriatric Medicine Division.
Dr. Nayfield comes with an
extensive, multi-faceted education and
training followed by 19 years of
experience in key leadership roles at the
National Institutes of Health, first at the
National Cancer Institute and later at
the National Institute on Aging, where
she worked as Chief of the Geriatrics
Branch, Geriatrics and
Clinical Gerontology
Extramural Program.
By participating
in countless initiatives,
fostering and promoting
competitive funding of
research at the national
level, and serving as
a mentor and Susan Nayfield, M.D., M.Sc.
counselor of several rising and estab-
lished stars in research, Dr. Nayfield has
become a nationally recognized leader
in key scientific areas related to aging.
Her valuable advice played a
significant role in the direction of the
overall research of the IOA team, which
has resulted in building one of the most
successful and highest funded interdis-
ciplinary research programs on aging in
the nation.
Dr. Nayfield brings outstanding
experience, talent and leadership to our
team, which are critical in the current
time of unprecedented growth of our
Department and Institute.
Pleasejoin me in welcoming
Dr. Nayfield! #










UF Seeks Older Adults
Continued from page 1

and practicality of two interventions:
a physical activity program and a
successful aging health education
program.
"We want to change how
people live," said principal inves-
tigator Marco Pahor, director of
UF's Institute on Aging. "Modifying
lifestyle is an important approach to
maintaining independence, which is
one of our public health and clinical
priorities for older adults."
Eligible participants are ran-
domly assigned to take part in either
a structured physical activity program
that includes moderate-intensity
physical activity such as walking and
exercises to improve strength, bal-
ance and flexibility, or in a successful
aging program that includes health
education workshops and supervised
stretching. Individuals will be followed
for up to approximately four years.
In addition to disability pre-
vention, investigators are examining
whether physical activity and health
education affect cognitive function,
cardiovascular and cardiopulmonary
events, falls and disability; they are
also reviewing quality-of-life measures
such as depression symptoms, sleep
quality, stress and satisfaction with life.
To enroll or learn more about
the LIFE Study, call 352-273-5919 or
toll-free 866-386-7730..



The IOA Receives Award
Continued from page 1

"In recognition of the
strength of the existing IOA pro-
grams and the fact that Florida has
the largest proportion of elderly
adults of all the United States, the


The Resveratrol for Improved Performance in the
Elderly (RIPE) Trial at the IOA
T he UF Institute on
Aging scientists are
recruiting particip-
ants for a clinical trial to
test whether Resveratrol, a
compound found in red wine
and dark-skinned grapes, can
help improve memory and
physical functioning in older
adults. In animal studies,
Resveratrol has been shown
to improve memory and
protect against cardiovascular
diseases, cancers and other
age-related changes. Resveratrol is and the mechanisms through which
also one of a small number of com- it produces observed results. Addi-
pounds shown to extend lifespan in tionally, the study will assess Resvera-
flies, fish and other organisms. trol's impact on reducing fatigue lev-
"If Resveratrol is found to els and fat content of muscles among
have a beneficial impact, the supple- other areas of potential impact.
ment might be a potential treatment The RIPE Trial seeks 30 vol-
option to fight age-related cognitive unteers between age 65 and 100 who
decline," said Todd Manini, Ph.D., lead a sedentary lifestyle to take part
who is co-principal investigator with in the 12-week phase I trial. Partici-
Steve Anton, Ph.D. pants must be non-smokers who do
Titled the Resveratrol for Im- not regularly drink red wine and are
proved Performance in the Elderly able to walk one mile.
(RIPE) Trial, the study will provide To enroll or learn more
insights about the effects of Resvera- about the RIPE study, call 352-273-
trol on specific areas of the brain 5919 or toll-free 866-386-7730.#


National Institutes of Health have
awarded a grant for constructing a
nearly 40,000 square-foot building
intended to support our Institute's
determination to further develop
age-related research.
This facility will enhance the
alliance between basic science, clini-
cal, epidemiology and health services
researchers by enabling them to
share resources and work under the
same roof on a common goal: im-
proving the health and independence
of older adults. Additionally, this


project will create over 370 perma-
nent and temporary jobs," said Dr.
Marco Pahor, principal investiga-
tor of the grant and director of the
IOA.
The four-story building will
be constructed on the University of
Florida's Gainesville campus, and
is designed following the LEED
Platinum certification the highest
level of environmental sustainability,
energy conservation and pollution
reduction, according to the standards
of the US Green Building Council. #











Dr. Leeuwenburgh and Dr. Bazikian Make an
Unprecedented Gift to the IOA


Dr. Christiaan Leeuwenburgh (left) and
Dr. Yvette Bazikian (right)
The Institute on Aging is
grateful to Drs. Leeuwen-
burgh and Bazikian for their
generous estate gift. Dr. Leeuwen-
burgh is Chief of the Division of
Biology of Aging and Professor of
Aging and Geriatrics. Dr. Bazikian is
a physician at North Florida Region-
al Hospital.
The newlyweds' gift is an ex-
pression of their commitment both
to each other and to the IOA. They


The Cognitive Aging and M

Dr. Marco Pahor, Director
of the Institute on Aging,
was recently appointed the
program coordinator for the newly
established Cognitive Aging and
Memory Clinical Translational Re-
search Program (CAM-CTRP). The
ultimate goal of the CAM-CTRP
is to develop clinical applications to
slow, avert or restore age-related
cognitive decline and memory loss.
Dr. Pahor and Dr. Thomas
Foster, professor of N 1 iir... i1n. .
and McKnight Chair for Research
on Aging and Memory, hosted a
meeting for distinguished guests from
the Board of Trustees for the Mc-
Knight Foundation for Brain Re-
search. Students, faculty and staff


meaningfully expressed their reason
for making the gift: "The outstand-
ing mission of the IOA and the in-
credibly hard working staff, students
and faculty make it easy to support
the IOA mission."
Dr. Leeuwenburgh believes
that funding contributions to Geri-
atric and Gerontological Research
will ensure novel interventions and
treatment in Florida, supporting his
dream for the state to become an
example for "Healthy Aging."
A long-time Gator, Dr. Leeu-
wenburgh completed his B.S. and
M.S. at the University of Florida. He
sincerely feels that it is important to
give back in order to show apprecia-
tion for all that he has received.
Drs. Leeuwenburgh and Ba-
zikian hope that their gift will con-
tribute to the IOAs success for many,
many years to come.


emory Program

from the entire UF campus were
invited to attend presentations by
McKnight Brain Institute faculty
and researchers, focusing on aging
and cognitive decline. Among these
speakers were two core leaders of the
Pepper Center, Dr. Michael Marsiske
and Dr. Chri-i) Carter, and one of
our junior scholars, Zvinka Zlatar.
Dr. Joe Verghese, Associate
Professor of Neurology at the Al-
bert Einstein College of Medicine
and Louis and Gertrude Feil Faculty
Scholar in Neurology, delivered a
keynote presentation on remediating
cognitive decline in the elderly.
The search for the future
CAM-CTRP Program Director is
ongoing.


Welcome To Our New
Faculty and Staff:
Pam Krueger, Program Assistant;
Lea-An Steiner, Study Coordinator;
Mallorey Picone, Screener; Alethea Geiger,
Receptionist; Melissa Lewis, Study
Coordinator; Deborah Hiatt-Jensen, NP-C;
Allison Martin, MS, Senior Interventionist;
Belinda Scurlock, Division Manager;
Sarah Drawver, Data Entry Operator.

New Faculty Spotlight:
Thomas Buford, Ph.D. joined our team in
2009 following completion of his Ph.D. in
Exercise, Nutrition and Preventative Health
at Baylor University. After a brief period as
a Research Associate, he was promoted to a
faculty position at the rank of Lecturer. Dr.
Buford's research interests center on age-
related changes in skeletal muscle physiol-
ogy. His translational research program is
focused on improving quality of life for older
individuals by developing practical methods
for improving muscle strength and mobility.
Presently, Dr. Buford is researching the role of
the vasculature on regeneration, a key process
in the maintenance of skeletal muscle mass.
Dr. Buford has published over a dozen articles
in journals such as Medicine and Science in
Sports and Exercise, European Journal of
Applied Physiology, and Applied Physiology,
Nutrition, and Metabolism.
He was also recently awar-
ded a KL2 Career Devel-
opment Award through the
UF Clinical and Translat-
ional Science Institute to
support his ongoing
research. Thomas Buford, Ph.D.

Opportunities to Participate
In Research Studies:
If you are interested in participating in one
of our current or future studies, you can
now enroll in our IRB approved recruitment
registry. To enroll or obtain additional infor-
mation, call 1-866-386-7730 or email Peggy
Smith at psmith@aging.ufl.edu.

New Positions:
We are currently advertising several faculty
and staff positions; more positions will be
posted soon. For employment opportuni-
ties, please visit the University of Florida's
website at http://jobs.ufl.edu or email
Camelia Pascu at cpascu@aging.ufl.edu.






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Giving to the Institute on Aging

...why every dollar counts

Unlocking life's mysteries particularly the secrets of how long and how

well we live -is the distinct focus of the University of Florida's Institute on
Aging. Our scientists and physicians are dedicated to achieving better un-
derstanding of the mechanisms of aging and how we can maintain or enhance our
physical independence and cognitive abilities.

Private philanthropy is so essential to our work. Your gift, regardless of size, can
make the critical difference in funding new scientific endeavors. Imagine discoveries
that fuel positive cellular changes; identify new therapies that help rehabilitate aging
bones and joints; or uncover additional pharmaceutical allies. Private philanthropy
makes all this and much more possible.

To learn more about how you can invest in a healthier and more independent to-
morrow for us all, please contact Sandra Fackler, Senior Director of Development,
at (352)265-7227 or sfackler@ufl.edu.


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