• TABLE OF CONTENTS
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 Front Cover
 Table of Contents
 Statement from the Chairman
 Department organizational...
 Graduate medical education
 Department research
 Individual divisions
 Back Cover






Title: Department of Medicine annual report
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 Material Information
Title: Department of Medicine annual report academic year 2007 - 2008
Series Title: Department of Medicine annual report
Physical Description: Serial
Language: English
Creator: College of Medicine, University of Florida
Publisher: College of Medicine, University of Florida
Place of Publication: Jacksonville, Fla.
Publication Date: 2007-2008
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Bibliographic ID: UF00090036
Volume ID: VID00002
Source Institution: University of Florida
Holding Location: University of Florida
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Table of Contents
    Front Cover
        Front Cover
    Table of Contents
        Page 1
        Page 2
    Statement from the Chairman
        Page 3
        Page 4
    Department organizational overview
        Page 5
        Page 6
        Page 7
        Page 8
    Graduate medical education
        Page 9
        Page 10
        Page 11
    Department research
        Page 12
    Individual divisions
        Page 13
        Page 14
        Page 15
        Page 16
        Page 17
        Page 18
        Page 19
        Page 20
        Page 21
        Page 22
        Page 23
        Page 24
        Page 25
        Page 26
        Page 27
        Page 28
        Page 29
        Page 30
        Page 31
        Page 32
        Page 33
        Page 34
        Page 35
        Page 36
        Page 37
        Page 38
        Page 39
        Page 40
        Page 41
        Page 42
        Page 43
        Page 44
    Back Cover
        Back Cover
Full Text







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Department of Medicine


TABLE OF CONTENTS
ACADEMIC YEAR 2008 (7/07 6/08)


I. Statement from the Chairman

II. Department Organizational Overview
a. Administration
b. Division Chiefs
c. Residents/Fellows

III. Graduate Medical Education
a. Internal Medicine Residency Training Program
b. Subspecialty Fellowship Program
c. Student Education Programs

IV. Department Research

V. Individual Divisions
a. Cardiology
b. Endocrinology
c. Gastroenterology
d. General Internal Medicine
e. Hematology/Oncology
f. Hospital Medicine
g. Infectious Disease
h. Nephrology and Hypertension
i. Pulmonary and Critical Care
j. Rheumatology




















Department of Medicine
University of Florida
College of Medicine Jacksonville
653-1 West 8th Street, L20
Jacksonville FL 32209
904-244-8846
www.hscj.ufl.edu/im/


Annual Report AY 2008 Department of Medicine


Table of Contents


Annual Report AY 2008


Department of Medicine








Department Chair: Arshag Mooradian, MD


STATEMENT FROM THE CHAIRMAN
ACADEMIC YEAR 2008 (7/07 6/08)

Dear Colleagues and Friends:

I am happy to share with you the Annual Report of the Department of Medicine at the University of Florida College
of Medicine Jacksonville for the academic year July 2007 through June 2008. I will briefly describe the
departmental accomplishments for the past year.

Patient care: The Department expanded clinical activities and achieved 103% of the budgeted revenues. The
faculty members in 7 out of 10 divisions continued to exceed the 75% percentile of MGMA RVU benchmarks. The
Department was successful in attracting talented faculty in all of its divisions. The service contracts with the
Veterans' Administration and the Department of Health in Duval County were maintained throughout the fiscal
year. Continued improvements in clinical operations helped cost containment and enhanced efficiency.

Education: Faculty members of the Department continue to excel in their mission of educating students and
residents. The Department has once again been the winner of the Golden Apple Award for the best clinical
clerkship. This is an exceptional honor that the Department has received year after year. There were 16 faculty
members in the Department who received the Exemplary Teacher Award. This is an unprecedented number of
awards that the departmental faculty receives. In addition, the Outstanding Clinical Educator Award of Physician
Assistants program was given to Dr. Irene Alexandraki of the Division of General Internal Medicine. The scholarly
productivity of the house staff increased substantially and the top prizes of the Annual Research Day were awarded
to the residents and fellows within the Department.

New Fellowship programs were initiated as follows: Nephrology Fellowship started on July 1, 2007, while
Endocrinology, Pulmonary and Critical Care and Cardiac Electrophysiology Fellowships were approved to start July
1, 2008.

New Continuing Medical Education (CME) initiatives were launched in Nephrology, Endocrinology and
Oncology in addition to traditional CME's offered by the other divisions.

Research: The Department once again had an exceptionally productive year in research. There were a total of
119 peer reviewed publications and 15 book chapters authored by faculty members. Faculty made 34 national and
regional presentations. During fiscal year 2008, 54 research awards with a direct cost of $1,330,431 were acquired.
This represents a 147.2% change compared to the previous fiscal year.

I trust this brief synopsis of the Annual Report highlights the commitment of the departmental faculty to excellence
in patient care, education, and research.


Sincerely,


Arshag D. Mooradian, M.D.
Professor and Chairman


Annual Report AY 2008 Statement from the Chairman


Statement from the Chairman


Annual Report AY 2008


Statement from the Chairman








Organizational Overview


DEPARTMENT ORGANIZATIONAL OVERVIEW
ACADEMIC YEAR 2008 (7/07 6/08)

Arshag D. Mooradian, M.D.
Chairman, Department of Medicine

N. Stanley Nahman, M.D.
Program Director, Internal Medicine Residency and Associate Chair, Department of Medicine

Linda R. Edwards, M.D.
Associate Chair, Department of Medicine

Arpitha Ketty, M.D.
Associate Program Director, Graduate Medical Education

Olga Petrucelli, M.D.
Associate Program Director, Graduate Medical Education

Carlos Palacio, M.D.
Director, Medical Student Clerkship

Irene Alexandraki, M.D.
Associate Director, Medical Student Clerkship

Christina Catalano, M.B.A.
Administrator

Nanci Morton
Administrative Manager

DIVISION CHIEFS


Cardiology

Endocrinology, Diabetes & Metabolism

Gastroenterology

General Internal Medicine

Hematology & Medical Oncology

Hospital Medicine

Infectious Disease

Nephrology and Hypertension

Pulmonary, Critical Care & Sleep Medicine

Rheumatology & Clinical Immunology


Theodore Bass, M.D.

Kent R. Wehmeier, M.D.

Louis Lambiase, M.D., M.H.A.

Linda R. Edwards, M.D.

Fauzia Rana, M.D.

Jeffrey House, D.O.

Michael Sands, M.D., M.P.H. &T.M.

N. Stanley Nahman, Jr., M.D.

J. Davis Cury, M.D.

Ghaith Mitri, M.D., M.M.M.


Annual Report AY 2008 Organizational Overview


Department of Medicine


Annual Report AY 2008


Organizational Overview





Organizational Overview


RESIDENTS/FELLOWS


Chief Residents 2007-2008

Nikolaos Anatoliotakis, M.D.
Sian S. Chisholm, M.D.


University of Crete Faculty of Medicine
Ross University School of Medicine


Class of 2007-2008


Medical School


Rajarshi Chakravarty, M.D.
Paul Gilreath, M.D.
Christopher Hseih, M.D.
Tarif Khair, M.D.
Brandon Kinney, M.D.
Ravindra Maharaj, M.D.
Jasdip Matharu, M.D.
Archer Martin, M.D.
Peyman Mazidi, M.D.
Michael Nguyen, M.D.
Quang Nguyen, M.D.
Ricardo Nieves-Ramos, M.D.
Taren Ohman, M.D.
John-Paul Pham, M.D.
Tauseef Qureshi, M.D.
Karishma Ramsubeik, M.D.
Jon Rosensweig, M.D.
Naveen Seecheran, M.D.
Atman Shah, M.D.
Ho Vu, M.D.
Edward Yazigi, M.D.


Housestaff II


St. George's University School of Medicine
Medical College of Georgia
Ohio State University College Of Medicine
American University of Beirut
University of Texas Medical School
University of West Indies Trinidad
St. George's University School of Medicine
University of South Florida College of Medicine
Flinders University of South Australia
University of Miami School of Medicine
University of South Florida College of Medicine
Ohio State University College Of Medicine
St. George's University School of Medicine
Marshall University School of Medicine
St. George's University School of Medicine
University of West Indies Trinidad
Drexel University College of Medicine
University of West Indies Trinidad
Ross University School of Medicine
Ross University School of Medicine
Ross University School of Medicine


Medical School


Melvin Bullock, M.D.
Andrew Darlington, D.O.
Friba Faqeeri, M.D.
Somajita Ghosal, M.D.
Mohammad Asif Khan, M.D.
Carol Le, M.D.
Nimish Naik, M.D.
Thomas Nguyen, M.D.
Vinny Samuel, M.D.
Vandana Seeram, M.D.
Siva Suryadevara, M.D.
Esther Vildor-Dazil, M.D.


Housestaff III


Medical College of Georgia
Philadelphia College of Osteopathic Medicine
Ross University School of Medicine
Calcutta National Medical College
Khyber Medical College
Medical College of Wisconsin
New York Medical College
Drexel University College of Medicine
Ross University School of Medicine
University of West Indies Trinidad
University of West Indies Trinidad
Florida State University College of Medicine


Medical School


Rosalyn Alcalde, M.D.
Gina Chacon, M.D.
Ruchi Gupta, M.D.
Michael Hernandez, M.D.
Victor Lopez de Mendoza, M.D.
Ashwin Mehta, M.D.
Latonia Moncur, M.D.
Soo Nam, M.D.
Timmy Nguyen, M.D.
Juan Daniel Pulido, M.D.
Shilpa Reddy, D.O.


Ross University School of Medicine
Universidad Catolica de Santa Maria
Lady Hardinge Medical College
Florida State University College of Medicine
Universidad Central Del Este
St. George's University School of Medicine
St. George's University School of Medicine
Ross University School of Medicine
Flinders University of South Australia
Universidad de Ciencias Medicas
Nova Southeastern University


Annual Report AY 2008 Organizational Overview


Housestaff I


Department of Medicine


Annual Report AY 2008


Organizational Overview





Organizational Overview


Subspecialty Fellowship Program Directors

Cardiology
Gastroenterology
Interventional Cardiology
Infectious Disease
Medical Oncology
Nephrology

Subspecialty Fellow Housestaff IV

Aamir Amin, M.D. (Cardiology)
Wayne Cheng, M.D. (Cardiology)
Noel Dasgupta, M.D. (Cardiology)
Taylor Dowsley, M.D. (Cardiology)
Supriya Mannepalli, M.D. (Infectious Disease)
Aasita Patel, M.D. (Cardiology)
Ivan Rascon-Aguilar, M.D. (Gastroenterology)
Haritha Sakhamuri, M.D. (Nephrology)
Amit Shah, M.D. (Cardiology)
Aja Smith-McCutchen, M.D. (Gastroenterology)
Robert Sullivan, M.D. (Nephrology)
Thomas Walsh, M.D. (Cardiology)
Robert Zaiden, M.D. (Medical Oncology)

Subspecialty Fellow Housestaff V

M. Kamran Aslam, M.D. (Cardiology)
Matthew Cole, M.D. (Gastroenterology)
Nikesh Jasani, M.D. (Medical Oncology)
Lori McMullan, M.D. (Cardiology)
A. Tony Ortiz, M.D. (Cardiology)
Sunitha Pudhota, M.D. (Gastroenterology)
Peyman Salimi-Tari, M.D. (Medical Oncology)
Stuart Smalheiser, M.D. (Cardiology)
Derek Sun, M.D. (Cardiology)
Jose Vindas-Cordero, M.D. (Infectious Disease)

Subspecialty Fellow Housestaff VI

Mary Alizadeh, M.D. (Gastroenterology)
Amitra Caines, M.D. (Cardiology)
Binu Jacob, M.D. (Cardiology)
Joe Khoury, M.D. (Gastroenterology)
Dao Pham, M.D. (Cardiology)
Ian Weisberg, M.D. (Cardiology)

Subspecialty Fellow Housestaff VII

Lyndon Box, M.D. (Interventional Cardiology)
Chris Pavlovic, M.D. (Interventional Cardiology)


Steven Lavine, M.D.
Louis Lambiase, M.D.
Ted Bass, M.D.
Michael Sands, M.D.
Janet Hosenpud, M.D.
N. Stanley Nahman, Jr., M.D.

Medical School


Texas A & M University College of Medicine
University of Florida College of Medicine
University of Wisconsin Medical School
Finch University of Health Science Chicago Medical School
Mangalore University Kasturba Medical College
University of Illinois College of Medicine
Universidad de San Carlos
PSG Institute of Medical Sciences
University of Alabama School of Medicine
Case Western Reserve University School of Medicine
Ross University School of Medicine
University of Miami School of Medicine
St. Matthews University School of Medicine

Medical School

University of Texas Southwestern Medical School
Ross University School of Medicine
St. George's University School of Medicine
Louisiana State University School of Medicine
Universidad Central del Este
Osmania Medical College
Flinders University of South Australia
University of Miami School of Medicine
Drexel University College of Medicine
Universidad de Costa Rica, San Jose

Medical School

University of Colorado School of Medicine
Case Western Reserve University School of Medicine
University of Miami School of Medicine
Lebanese University Faculty of Medicine
University of Alabama School of Medicine
Emory University School of Medicine

Medical School


University of Alabama School of Medicine
Washington University School of Medicine


Annual Report AY 2008 Organizational Overview


Department of Medicine


Annual Report AY 2008


Organizational Overview








Program Director: N. Stanley Nahman, Jr MD


GRADUATE MEDICAL EDUCATION
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

Academic year 2007-2008 is another landmark year for the Graduate Medical Education (GME) Program as it relates to the
Department of Medicine. The GME program had strong showing in a number of arenas. Under the leadership of Dr. Nahman,
the GME programs grew in size and strength. Faculty and residents continued to excel in all areas of education and research.

Internal Medicine Residency Program: The core program continued to mature under the Program Director, Dr. Stan Nahman
and Associate Program Directors Dr. Arpitha Ketty and Dr. Olga Petrucelli. Consistent with the preceding year, the intern class
was the strongest class yet as measured by the USMLE Step 1 scores. The class blended into the program with relative ease.
The innovation, resourcefulness and flexibility in the program continues to shape curricular activities as well exemplified by the
initiation of Internal Medicine and Emergency Medicine interdepartmental conferences and the ambulatory clinic intense
orientation sessions both of which have been very well received by the PGY-1 class. Efforts and dedicated work of all faculty
bore fruit this year with the graduating class registering a 93% ABIM board pass rate. This reemphasized the need to bolster all
the successful facets of the program including the Board Review course, mentoring program, mega team and night float rounds.

The program was well served by the two Chief Medical Residents (CMR), Dr. Nik Anatoliotakis and Dr. Sian Chisholm, who
graduated at the beginning of the year. Among the others, six went on to pursue subspecialty fellowship training. Drs. Ketty,
Petrucelli, and Alexandraki completed the 18 month Master Educator Program sponsored by the University of Florida and
became peer reviewers for other faculty. In research, residents submitted abstracts to the Florida ACP, American Society of
Nephrology, and Southern Section of the AFMR. They accounted for 5 internal research grants, 4 published manuscripts, 8
published abstracts and almost 20 poster presentations.

Subspecialty Fellowship Program: This was another great year marking the successful start of the Endocrine Fellowship and the
first set of fellows starting the following year. This adds to the six other successful fellowship programs of Cardiology,
Interventional Cardiology, Gastroenterology, Medical Oncology, Nephrology and Infectious Disease. The Nephrology Fellowship
that started the previous academic year started to mature. Pulmonary and Critical Care Medicine and Cardiac Electrophysiology
are set to apply for their own fellowship to start the next academic year. Gastroenterology will have a site visit in the summer of
2008.

Student Education: Drs. Alexandraki and Palacio continue to head student education and have been recognized for their efforts.
Students continue to have rotations in inpatient and ambulatory setting. They also complete a two week required Geriatrics
Clerkship during the 4th year.


LISTING OF PROGRAM LEADERSHIP

New Faculty
Nik Anatoliotakis, MD, Post-doctoral Associate and Chief Medical Resident
Medical School / Graduation date University of Crete
Internship/residency and year University of Florida Jacksonville 2007
Chief Medical Resident University of Florida Jacksonville 2008

Sian Chisholm, MD, Post-doctoral Associate and Chief Medical Resident
Medical School / Graduation date Ross University
Internship/residency and year University of Florida Jacksonville 2007
Chief Medical Resident University of Florida Jacksonville 2008

Current Faculty
Irene Alexandraki, MD, Assistant Professor and Associate Student Clerkship Director
Medical School / Graduation date University of Athens Medical School 1989
Internship/residency and year Hahneman University 1998
Subspecialty training and year Infectious disease/Baylor College of Medicine 2001

Arpitha Ketty, MD, Assistant Professor and Associate Program Director
Medical School / Graduation date University of Southern California 1999
Internship/residency and year University of California Davis 2002

N. Stanley Nahman, Jr., MD, Professor and Program Director
Medical School / Graduation date Medical College of Ohio 1979
Internship/residency and year Presbyterian Hospital Denver, Mt Carmel Health, Columbus 1984
Subspecialty training and year Nephrology/The Ohio State University 1987


Graduate Medical Education


Annual Report AY 2008


Graduate Medical Education





Program Director: N. Stanley Nahman, Jr MD


Carlos Palacio, MD, Assistant Professor and Student Clerkship Director
Medical School / Graduation date University of Miami
Internship/residency and year University of Florida Jacksonville
Chief Medical Resident University of Florida Jacksonville

Olga Petrucelli, MD, Assistant Professor and Associate Program Director
Medical School / Graduation date University of South Florida
Internship/residency and year University of Chicago


1993
1996
1997


1996
1999


PUBLICATIONS

Khan MA*, Renganathan R. Varying practices of Warfarin dosing regimen, could we modify this? Irish Medical Journal. 2007.

Sullivan R*, Samuel V*, Le C*, Khan M*, Alexandraki I, Cuhaci B, Nahman Jr NS: Hemodialysis catheter-related bacteremia. Am J Med Sci.
2007 Dec;334(6):458-65.

Shepherd TM*, King MA, Yachnis AT, Ozarslan E, Blackband SJ. Cytoarchitectural Basis for Diffusion Anisotropy in the Human Hippocampus.
AJNR Am. J. Neuroradiol. May 2007;28(5):958-64.

Barmoutis A, Vemuri BC, Shepherd TM*, Forder JR. Tensor Splines for Interpolation and Approximation of DT-MRI with Applications to
Segmentation of Isolated Rat Hippocampi. IEEE Trans Med Imaging. 2007 Nov;26(11):1537-46.

HONORS AND AWARDS


Jasdip Matharu,MD


Intern of the Year


Michael Hernandez, MD Resident of the Year


James Cury, MD


Teacher of the Year


Exemplary Teachers: (arranged alphabetically)

Drs. Irene Alexandraki, Theodore A. Bass, James D. Cury, Linda R. Edwards, Malcolm T. Foster, Luis Guzman,
Steve S. Hsu, Arpitha K. Ketty, Ghania Masri, Senthil R. Meenrajan, Alan B. Miller, N. Stanley Nahman Jr., Carlos
Palacio, Olga M Petrucelli, Michael Sands and Elisa M. Sottile.

Clinical Teacher of the Year & Excellence in Student Education Award:

Irene Alexandraki, M.D. was named Clinical Teacher of the Year for the Jacksonville regional campus by UF
Physician Assistant Program graduates. The announcement was made during commencement in Gainesville on
Saturday, June 21.

Alexandraki also received the Excellence in Student Education Award during the College of Medicine-Jacksonville
resident graduation on June 18.

ENDOWMENTS AND GIFTS

The Anne and Max Michael, Jr. Education Fund Established 2006, by Anne Michael

GRANTS AND CONTRACTS

Principal Sponsor/Title
Investigator
Sullivan, Robert University of Florida Dean's Fund Resident Research Grant/ Risk factors for gram negative bacteremia and central venous
dialysis access

Zaiden, Robert University of Florida Dean's Fund Resident Research Grant/ Effect of hepatitis C infection on cellular immunity in
hemodialysis patients

Lopez de Mendoza, University of Florida Dean's Fund for Residents and Fellows Research Grant, "Changes in hemodialysis blood circuit
Victor parameters as predictors of catheter loss in dialysis patients".


2008

2008

2008


Graduate Medical Education


Annual Report AY 2008


Graduate Medical Education






Program Director: N. Stanley Nahman, Jr MD


Reddy, Shilpa University of Florida Dean's Fund for Residents and Fellows Research Grant: "Effect of hepatitis C viral load on bacteremic
events in hemodialysis patients".

Sakhamuri, Haritha University of Florida Dean's Fund for Residents and Fellows Research Grant: "The incidence of transient proteinuria in
urinary tract infection".

Katta, Sarah University of Florida Dean's Fund for Residents and Fellows Research Grant: "Age-related changes to renal function in
patients with sickle cell disease."

Mehta, Ashwin University of Florida Dean's Fund for Residents and Fellows Research Grant: "Enlighten encouraging dialogue about
decisions to limit life sustaining treatment using educational videos."

Pulido, Danny University of Florida Dean's Fund for Residents and Fellows Research Grant: "The Incidence of Cardiovascular Diseases in
Athletes and Methods of Screening."

Panse, Neeta University of Florida Dean's Fund for Residents and Fellows Research Grant: "Trends in Inflammatory Breast Cancer,
Incidence and Survival at UF Jacksonville."

Gupta, Ruchi University of Florida Dean's Fund for Residents and Fellows Research Grant: "Use of Acid Suppression Therapy In
Hospitalized Patients-Going Beyond The Indications."

Darlington, Andrew University of Florida Dean's Fund for Residents and Fellows Research Grant: "The use of thromboelastography as a tool to
predict tunneled catheter loss."

Shepherd, Timothy University of Florida Dean's Fund for Residents and Fellows Research Grant, 2007: "High Resolution MRI of Hippocampal
Sclerosis using the Diffusion Orientation Transform."


POST

Graduate


Outgoing Chiefs
Nik Anatoliotakis, MD

Sian Chisholm, MD


Graduating residents
1. Shilpa Reddy, MD
2. Rosalyn Alcalde, MD
3. Soo Nam, MD
4. Ashwin Mehta, MD
5. Ruchi Gupta, DO

6. Michael Hernandez, MD
7. Timmy Nguyen, MD
8. Danny Pulido, MD
9. Victor Lopez Mendoza, MD
10. Latonia Moncur, MD
11. Gina Chacon, MD


-GRADUATE ACTIVITIES OF CMR AND SENIOR RESIDENTS

Professional status Location


Fellowship, Cardiology 2008

Hospitalist




Chief Medical Resident
Chief Medical Resident
Hospitalist
Fellowship, Sleep Medicine
Hospitalist
Fellowship, Gastroenterology, 2009
Hospitalist
Fellowship, Oncology
Fellowship, Pulmonary/Critical Care
Fellowship, Nephrology
Private Practice
Research


Greece

University of Florida Jacksonville




University of Florida Jacksonville
University of Florida Jacksonville
Melbourne, FL
Miami, Florida
University of Florida Jacksonville
University of Missouri Columbia
University of Florida Jacksonville
University of Florida Jacksonville
University of Florida Jacksonville
University of Florida Jacksonville
Bahamas
University of Michigan


Graduate Medical Education


Graduate Medical Education


Annual Report AY 2008





Department of Medicine


DEPARTMENT RESEARCH
ACADEMIC YEAR 2008 (7/07 6/08)


Clinical and basic research, as well as mentoring and fostering skill sets for formulating and solving problems in medicine, have
been a major focus of the Department this year. In July, the Robert C. Nuss Research Building was dedicated and Michael
Haas, Ph.D. (Endocrinology), Xiaoyu Li, M.D., Ph.D. (Gastroenterology), and Virginia Urquidi, Ph.D. (Nephrology &
Hypertension) moved into the remodeled facility.

Research was also the theme of a new conference sponsored by the Department of Medicine. Invited speakers from the
Departments of Medicine, Neurology, Pathology, and Surgery discussed topics associated with their current and future research
activities. The topic of each conference fell into three broad categories basic science, clinical science, and hospital systems
management. Speakers from the Department of Medicine as well as other departments were invited in order to bring together
individuals with similar interests and to enhance the formation of interdepartmental collaborations.

Extra effort has been made to enhance resident and sub-specialty resident training in clinical and/or basic science research.
Didactic lectures covering clinical study design, statistics, genomics and proteomics, and analysis of gene expression were
provided for faculty and trainees. A noon conference describing various research methodologies, as well as administration
issues, grant preparation, and the Institutional Review Board was presented to assist residents in preparing research proposals.
Campus research resources and mentoring was also discussed at the orientation for incoming residents.

At Research Day, the Department of Medicine was well represented when the awards were announced. Resident Andrew
Darlington, D.O. won first place with his abstract and oral presentation, Stuart Smalheiser, M.D. received second place,
and Ivan Rascon, M.D. received third place. In the poster category, Joe Khoury, M.D. won first place and Amitra Caines,
M.D. received fifth place. Several faculty presented posters Christina Bailey, M.D. (Infectious Disease), Michael Haas,
Ph.D. (Endocrinology), Xiaoyu Li, M.D., Ph.D. (Gastroenterology), Mae Sheikh-Ali, M.D. (Endocrinology) and Kent
Wehmeier, M.D. (Endocrinology). Dominick Angiollilo, M.D. (Cardiology) received the Researcher/Scholar of the Year
Award.


Annual Report AY 2008 Department Research


Department Research


Annual Report AY 2008


Department Research





Division Chief: Theodore Bass, MD


DIVISION OF CARDIOLOGY
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Cardiology had a strong year academically and clinically. Financially there were some struggles on the
professional side due to some errors in developing the fiscal budget for 08. On the technical side, (Shands Budget) Cardiology
had a strong year, with volumes being up and expenses remaining under flex budget.

The Division had a great deal of growth in FY 08 in regards to programs and facility space. We opened a 14 bed state-of-the-
art Pre/Post Intervention Unit, located directly across from the Catheterization/Electrophysiology suites. In this area we added
an Inpatient Nuclear Camera. This is the 2nd nuclear camera for Cardiology. This camera is used for performing nuclear studies
on all inpatients and ED patients requiring this service. Also in this area, we added the Electrophysiology administrative suite.
The Electrophysiologist, ARNP and support staff are housed in this area, as well as a state-of-the-art conference room. We
are in preparation to start the Electrophysiology Fellowship program in FY 10, which will also be housed in this area.

The Division of Cardiology developed a partnership with The Department of Radiology for an Advanced Cardiac Imaging
Program. With this partnership, professional fees for all advanced cardiac imaging (PET/CT/MRI/Nuclear) are split 50/50
between cardiology and radiology. A quality assurance program and an educational program are being developed along with
an at home reading program that will allow for off-hours testing.

The Division continues to practice in Lake City, Florida and St. Mary's, Georgia, both being strong practices which ramped up in
volume over the past year. Lake Shore opened a diagnostic Cath Lab in November 2007, in collaboration with The CV Center.
We provide Medical Directorship for this new Catheterization Lab. The Division is also in discussions with The Live Oak Shands
Hospital to offer Cardiology Services out of this hospital (an outpatient clinic). Live Oak is approximately 20 minutes outside of
Lake City and appears to be underserved in cardiovascular medicine.

The Peripheral Vascular Program continues to be strong under the leadership of Dr. Luis Guzman. Our volume of peripheral
cases has remained steady.

Dr. Lyndon Box, Interventional Fellow, who will be staying on as faculty July 1, 2008, worked very aggressively this year with
the local EMS to develop protocols for STEMI patients, develop educational programs for EMT's regarding STEMI's, and work
with EMS on state and national legislation issues regarding dedicated PCI hospitals. He has also been instrumental in working
with local EMS on standardizing the Electronic EKG transmission systems for ambulances. A program was presented to the
Hospital regarding purchasing devices for accepting EKG transmission from EMS services in surrounding counties. This program
should start in FY 09, and a STEMI Coordinator will be hired.

In regards to the in-house STEMI program, developed April 2007, the program is going strong. The Emergency Department
(ED) was given authorization to alert the Call Team for STEMI's. We put new EKG protocol in place in the ED and standardized
many other procedures. In doing this we have been able to significantly decrease the Door to Balloon time for STEMI pts.

Cardiology continues to work diligently with the Emergency Department on the development of a Chest Pain Center. All policies
and protocols are in place. The ED has set up a "virtual" Chest Pain Center. Cardiology is providing same day non-invasive
testing for these patients in order to expedite discharge. We will soon have an off-hours program in place for nuclear and
ECHO testing.

The division has worked closely with the Director of Information Services/ Medical Records/Coding in regards to improving
documentation and coding for the division. We have regular meetings with the Director to go over outliers in documentation
and new guidelines for documentation and coding. We did an extensive look into Health Grades reporting, pulling all morbidities
and researching the documentation and finding substantial problems with how Health Grades adjust for co-morbidities.

We did not do a great deal of marketing for the Cardiology Division this FY, as Shands did not roll out the 2nd phase of
Marketing, after the Branding Campaign. We do have a marketing campaign coming out in July 2008 for our Electrophysiology
Program. We also plan to heavily market the EMS partnership as a community service.

The below were the goals we had listed for FY 08. Most we have met. Some of the goals are a work in progress (The Chest
Pain Center/Documentation improvement).

In collaboration with Radiology, further develop the Cardiac Advanced Imaging Program (CT and MRI program).
Expand the Electrophysiology Program to satellite offices. Proceed with plans to start an EP Fellowship Program in FY
2007/2008.


Annual Report AY 2008


Cardiology


Cardiology





Division Chief: Theodore Bass, MD


Continue to expand the CHF program, adding a CHF consult service, and continue to develop a team of heart failure
specialists (Physicians/PA/pharmacy/dietary). Develop a data base for tracking all CHF pts. Market the program as
a full service CHF program.
Continue to develop the Peripheral Vascular Program. Look at adding a Vascular Medicine physician.
Work with the Emergency Department to develop a Chest Pain Center.
Work with EMS to develop a partnership for a Cardiac Alert Program, transmitting EKG's from the field.
Continue to focus on growth in satellite offices, work with Lake Shore Hospital on plans for a new Heart Cath Lab at
Lake Shore
Open a new 14 bed holding unit on the 5th floor across from the new labs.
Work with coding/medical records to improve coding procedures/morbidity documentation.
Marketing CV services in 2nd stage of branding campaign.
Additional faculty to support expanding programs to include CHF Cardiologist, Electrophysiology Cardiologists (2),
Interventional Cardiologist, and a Vascular Medicine physician.

Our Goals for FY 09 are as follows:

Continue to enhance the Advanced Imaging Program in collaboration with Radiology.
Offer off-hours testing for certain diagnostic non-invasive tests (ECHO/Nuclear)
Start a program with EMS where EKG's will be transmitted directly from the field
Continue our relationship with EMS for educational needs/community service.
Continue to work with the Emergency Department regarding a Chest Pain Center.
Open an outpatient clinic in Live Oak/provide Cardiovascular Medicine services to the Live Oak community.
Continue to recruit a Female Cardiologist to help start a Women's Program in Cardiology.
Recruit for a Heart Failure Director to help develop the Heart Failure Program.
Recruit for an additional Electrophysiologist, for our expanding EP program.
Continue to work with UF satellite offices on improving percent of in network referrals. Program for Physician liaison
with each office is in place, started April 08.
Work with VA physicians on a partnership
Continue improving STEMI Stat Program, bring a STEMI coordinator onboard.

Patient Care: As stated above, CV satellite offices continue to expand. Our Lake Shore office provides cardiovascular care
(physician visits as well as diagnostic testing) to Lake City and surrounding communities. Physicians rotate to the Lake City
office Monday-Friday. We look to expand these services to Live Oak.

We continue with the practice in St. Mary's, Georgia. This office is equipped with diagnostic testing equipment (ECHO
machine/stress testing). UF cardiologists rotate to the practice Monday through Friday. They cover office visits as well as
hospital consults at Camden Medical Center.

We continue to see an increase in downstream revenue from both locations.

The Electrophysiology Program continues to grow in volume. This area had a very strong year financially and in volume growth.
We have an additional Electrophysiologist joining our group in September 08. We are also upgrading the Monitoring system in
the EP Lab ( PRUKA) to make operations much more efficient. As stated above, we will move forward with plans for an
Electrophysiology Fellowship Program.

Our Quality scores in MI and CHF have seen a downward turn in the last few months. As we investigated this we found that
most of the patients who were "fallouts" were not on the Cardiology service. These were patients seen on other services (non-
cardiology). Solutions for these issues are being discussed.

Patient Satisfaction scores for both inpatient and outpatient services continue to be above the 85th percentile.

As stated above we continue to improve our Door to Balloon time, with advances in our STEMI Stat Program.

Education: We receive between 400-500 applications per year for five available spots in our Fellowship Program. Applications
are screened 18 months prior to the start of the program. This past year we received 510 applicants thru ERAS (Electronic
Residency Application Service) of which 54 were selected for interview. Individuals are invited based on medical school, quality
of the medical residency, USME scores, research performed, and letters of recommendations. Faculty evaluates candidates
based on interpersonal skills, academic potential, and clinical potential.

Faculty conducts 4 sessions of Board review for medical residents. Significant changes were made in the CCU service to shorten
rounds, enhance teaching, and faculty-resident interaction.

Fellows passing their boards are at 100% in both the Cardiovascular Disease and Interventional programs.


Cardiology


Annual Report AY 2008


Cardiology





Division Chief: Theodore Bass, MD


Research: The division has been involved in three main areas of research: clinical research, cardiovascular imaging, and
translational research.

Clinicalresearch: The division was involved in several multi-center sponsored research projects in the fields of heart failure,
arrhythmia electrophysiologyy), and coronary artery disease. We currently have 14 active sponsored research projects being
conducted at the Division of Cardiology. Among the trials of most relevance, our group was the first in Florida to apply
transmyocardial injection of gene therapy to promote angiogenesis in patients with coronary artery disease. The division
received IRB approval to conduct the first transmyocardial injection of bone marrow derived CD34+ stem cells to promote
angiogenesis in patients with coronary artery disease in Florida.

Cardiovascular Imaging Core Laboratories. The Core lab provides quantitative assessment of different cardiovascular
image modalities, including angiography, intravascular ultrasound and magnetic resonance imaging for clinical studies. Since
2001, the Core lab has been involved in several national and international clinical trials. This year we reported a large STLLR
clinical trial, in which on-line transfer of angiographic data via internet to our core-lab was performed.

Translational Research: We have continued to nurture the growth of our thrombosis research laboratory. In addition, the
state of the art assays for platelet function testing the research team has a medical director, a PhD, 2 post-doctoral research
fellows, and a laboratory technician. The thrombosis research laboratory currently performs numerous sponsored and
investigator initiated studies. The Thrombosis Research Laboratory is among the most involved in the country for
pharmacodynamic testing of antiplatelet agents under clinical development. We have also been involved in testing assays for
sponsors requiring FDA approval of novel devices. The research group is among the most prolific academically with numerous
peer-reviewed publications in major scientific journals.

Academic productivity: The scientific output of the Cardiovascular Division during this academic year has been remarkable.
This includes 37 peer-reviewed publications, 24 abstract presentations at national and international meetings, authorship to 4
book chapters, and editorship to 1 book.

Awards: Faculty members have received various research awards, both locally (Researcher/Scholar of the Year Award) and
nationally (Northwester Cardiovascular Junior Faculty Clinical Research Award). Faculty has mentored resident/fellow recipients
of research awards as well.

Community Involvement: We played vital roles in the both the Heart Walk and United Way programs during this academic
year. We also participated in the Women's and Topics in Cardiology Symposiums. Some of the faculty also participated in the
African American Symposium this year.

LISTING OF FACULTY MEMBERS

New Faculty
Steven B. Shoemaker, MD, Assistant Professor

Medical School / Graduation date University of Florida Gainesville, Florida 2001
Internship/residency and year University of Florida Gainesville, Florida 2004
Subspecialty training and year University of Florida Jacksonville, Florida 2007

Current Faculty
Dominick Angiolillo, M.D. Ph.D., Assistant Professor
Medical School / Graduation date The Catholic University of the Sacred Heart Medical School, Italy 1997
Internship/residency and year The Catholic University of the Sacred Heart Medical School, Italy 1997
Subspecialty training and year University Hospital of Salamanca, Spain/The Policlinico Agostino Gemelli 1998
University Hospital, Italy/San Carlos University Hospital 2003

Theodore Bass, M.D., Professor and Division Chief
Medical School / Graduation date Brown University 1976
Internship/residency and year Mayo Clinic 1979
Subspecialty training and year Boston University 1981

Douglas Chapman, M.D., Assistant Professor
Medical School / Graduation date Chicago Medical School 1984
Internship/residency and year University of Missouri 1987
Subspecialty training and year Michael Reese Hospital 1990

Donald Conetta, M.D., Associate Professor
Medical School / Graduation date Duke University 1970


Cardiology


Annual Report AY 2008


Cardiology






Division Chief: Theodore Bass, MD


Internship/residency and year Georgetown University 1975
Subspecialty training/year University of Florida 1977

Luis Guzman, M.D., Assistant Professor
Medical School / Graduation date University of Buenos Aires, Argentina 1982
Internship/residency and year Churruca-Visca Hospital, Argentina 1986
Subspecialty training and year Instituto Cardiovascular Buenos Aires, Argentina 1989

Steve Hsu, M.D., Assistant Professor
Medical School / Graduation date Washington University 1990
Internship/residency and year Thomas Jefferson University 1993
Subspecialty training and year Thomas Jefferson University 1997

Steven Lavine, M.D., Associate Professor
Medical School / Graduation date Temple University 1976
Internship/residency and year Temple University 1979
Subspecialty training and year Temple University 1981

Alan Miller, M.D., Professor
Medical School / Graduation date University of Pittsburgh 1966
Internship/residency and year Mount Sinai 1968
Internship/residency and year George Washington University 1971
Subspecialty training and year Cleveland Metropolitan Hospital 1973

David Nabert, M.D., Associate Professor
Medical School / Graduation date UMDNJ New Jersey Medical School 1988
Internship/residency and year Hackensack University Medical Center 1991
Subspecialty training and year Ochsner Medical Foundation 1999

Joseph Pensabene, M.D., Assistant Professor
Medical School / Graduation date The Chicago Medical School 1984
Internship/residency and year Overlook Hospital 1987
Subspecialty training and year Cardiovascular Disease, Northwestern Memorial Hospital 1990
Subspecialty training and year Interventional Cardiology, UCLA Medical Center 1991
Subspecialty training and year Cardiac CT and Cardiac MRI, University of Florida Jacksonville 2006

Robert Percy, M.D., Associate Professor
Medical School / Graduation date University of Mississippi 1973
Internship/residency and year University of Mississippi 1977
Subspecialty training and year Joslin Clinic 1979
Subspecialty training and year Mass General Hospital 1981

Martin Zenni, M.D., Associate Professor
Medical School / Graduation date University of Chicago 1986
Internship/residency and year Tufts University 1989
Subspecialty training and year Harvard Medical School 1992


PUBLICATIONS

Angiolillo DJ. ADP receptor antagonism: what's in the pipeline? Am J Cardiovasc Drugs 2007; 7:423-32.

Angiolillo DJ, Alfonso F. Clopidogrel-statin interaction: myth or reality? JAm Coll Cardiol2007; 50:296-8.

Angiolillo D.J., Bernardo E, Sabate M, Jimenez-Quevedo P, Costa MA, Palazuelos J, Hernandez R, Moreno R, Escaned J, Alfonso F, Banuelos C,
Guzman L, Bass TA, Macaya C, Fernandez-Ortiz A. Impact of Platelet Reactivity on Cardiovascular Outcomes in Patients with Type 2 Diabetes
Mellitus and Coronary Artery Disease. JAm Coll Cardiol2007; 50:1541-7.

Angiolillo DJ, Alfonso F. Platelet Function Testing and Cardiovascular Outcomes: Steps Forward in Identifying the Best Predictive Measure.
Thromb Haemost2007; 98:707-9.

Angiolillo DJ, Costa MA, Shoemaker SB, Desai B, Yuan H, Bernardo E, Charlton R, Guzman L, Zenni M, Bass TA. Functional Effects of High
Clopidogrel Maintenance Dosing in Patients with Inadequate Platelet Inhibition. AmJCardiol2008; 101:440-5.

Angiolillo D.J., Bernardo E, Palazuelos J, Desai B, Weisberg I, Alfonso F, Guzman LA, Hernandez-Antolin R, Escaned J, Banluelos C, Shoemaker
SB, Zenni MZ, Macaya C, Fernandez-Ortiz A, Bass TA. Functional impact of high clopidogrel maintenance dosing in patients undergoing elective
percutaneous coronary interventions. Results of a randomized study. Thromb Haemost. 2008;99:161-8.


Cardiology


Annual Report AY 2008


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Division Chief: Theodore Bass, MD


Moreno R, Fernandez C, Sanchez-Recalde A, Galeote G, Calvo L, Alfonso F, Hernandez R, Sanchez-Aquino R, Angiolillo DJ, Villarreal S, Macaya
C, Lopez-Sendon JL. Clinical impact of in-stent late loss after drug-eluting coronary stent implantation. EurHeartJ2007; 28:1583-91.

Box LC, Angiolillo DJ, Suzuki N, Box LA, Jiang J, Guzman L, Zenni MA, Bass TA, Costa MA. Variability of Atherosclerotic Plaque Characteristics in
Human Coronary Arteries disease: a Three-dimensional Intravascular Ultrasound Study. Catheter CardiovascInterv. 2007; 70:349-56.

Costa MA, Shoemaker S, Futamatsu H, Klassen C, Angiolillo DJ, Nguyen M, Siuciak A, Gilmore P, Zenni MM, Guzman L, Bass TA, Wilke N.
Myocardial Perfusion Reserve Determined by Magnetic Resonance Perfusion Correlates with Invasive Physiologic and Anatomical Assessments of
Coronary Artery Disease. JAm Coll Cardiol 2007; 50:514-22.

Futamatsu H, Wilke N, Klassen C, Shoemaker S, Angiolillo DJ, Siuciak A, Morikawa-Futamatsu K, Suzuki N, von Ziegler F, Bass TA, Costa MA.
Evaluation of Cardiac Magnetic Resonance Imaging Parameters to Detect Anatomically and Hemodynamic ally Significant Coronary Artery
Disease. Am HeartJ2007; 154:298-305.

Lotrionte M, Biondi-Zoccai GL, Agostoni P, Abbate A, Angiolillo DJ, Valgimigli M, Moretti C, Meliga E, Cuisset T, Montalescot G, Collet JP, Di
Sciascio G, Waksman R, Testa L, Sangiorgi G, Laudito A, Trevi GP, Sheiban I. Metaanalysis Appraising High Clopidogrel Loading In Patients
Undergoing Percutaneous Coronary Intervention. AmJCardiol2007; 100:1199-206.

Jimenez-Quevedo P, Sabate M, Angiolillo DJ, Alfonso F, Hernandez-Antolin R, Sanmartin M, Gomez-Hospital JA, Banuelos C, Escaned J, Moreno
R, Fernandez C, Fernandez-Aviles F, Macaya C; for the DIABETES Investigators. Long-term clinical benefit of sirolimus-eluting stent implantation
in diabetic patients with de novo coronary stenoses: long-term results of the DIABETES trial. EurHeartJ. 200;28:1946-52.

Alfonso F, Suarez A, Perez-Vizcayno MJ, Moreno R, Escaned J, Banuelos C, Jimenez P, Bernardo E, Angiolillo DJ, Hernandez R, Macaya C.
Intravascular Ultrasound Findings During Episodes of Drug-Eluting Stent Thrombosis. JAm Coll Cardiol2007; 50:2095-7.

Cavallari U, Trabetti E, Malerba G, Biscuola M, Girelli D, Olivieri O, Martinelli N, Angiolillo DJ, Corrocher R, Pignatti PF. Gene sequence variations
of the platelet P2Y12 receptor are associated with coronary artery disease. BMCMedical Genetics 2007; 8: 59-64.

Wiviott SD, Trenk D, Frelinger AL, O'Donoghue M, Neumann FJ, Michelson AD, Angiolillo DJ, Hod H, Montalescot G, Miller DL, Jakubowski JA,
Cairns R, Murphy SA, McCabe CH, Antman EM, Braunwald E; PRINCIPLE-TIMI 44 Investigators. Prasugrel compared with high loading- and
maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for
Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation. 2007;116:2923-32.

Guzman LA, Costa MA, Angiolillo DJ, Zenni M, Henquin R, Wludyca P, Silliman S, Bass TA. Staged Carotid Artery Stenting and CABG Surgery in
Patients with Concomitant Disease: A Review of the Available Information. Stroke 2008; 39:361-5.

Kawaguchi R, Sabate M, Angiolillo DJ, Jimenez-Quevedo P, Suzuki N, Corros C, Futamatsu H, Alfonso F, Hernandez-Antolin R, Macaya C, Bass
TA, Costa MA. Angiographic and 3D Intravascular Ultrasound Assessment of Overlapping Bare Metal Stent and 3Different Formulations of Drug-
Eluting Stents in Patients with Diabetes Mellitus. IntJ Cardiovasc Imaging 2008; 24(2):125-32.

Futamatsu H, Klassen C, Pilla M, Wilke N, Angiolillo DJ, Smalheiser S, Siuciak A, Suzuki N, Bass TA, Costa MA. Diagnostic Accuracy of
Quantitative Cardiac MRI Evaluation Compared to Stress Single-Photon-Emission Computed Tomography. International Journal of Cardiovascular
Imaging 2008; 24:293-9.

Oikawa Y, Yajima J, Angiolillo DJ, Akabane M, Funada R, Matsuno S, Inaba T, Nakagawa Y, Nakamura M, Sawada H, Aizawa T. Short- or long-
term outcomes of coronary artery aneurysms occurring after directional coronary atherectomy. JInvasive Cardiol. 2008 ;20:159-60.

Rossini R, Angiolillo DJ, Musumeci G, Scuri P, Invernizzi P, Bass TA, Mihalcsik L, Gavazzi A. Aspirin desensitization in patients undergoing
percutaneous coronary interventions with stent implantation. Am JCardiol. 2008;101:786-9.

Suzuki N, Nanda H, Angiolillo DJ, Bezerra H, Sabatd M, Jimenez-Quevedo P, Alfonso F, Macaya C, Bass TA, Ilegbusi OJ, Costa MA. Assessment
of potential relationship between wall shear stress and arterial wall response after bare metal stent and sirolimus-eluting stent implantation in
patients with diabetes mellitus. IntJ Cardiovasc Imaging. 2008 (in press).

Tamburino C, Angiolillo DJ, Capranzano P, Di Salvo M, Caggeggi A, Tomasello D, Capodanno D, Galassi AR, Ussia GP, Bass TA. Complete
Versus Incomplete Revascularization in Patients with Multivessel Disease Undergoing Percutaneous Coronary Intervention with Drug-Eluting
Stents. Catheter Cardiovasc Interv 2008 (in press).

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Antiplatelet
Therapy and Platelet Function Testing: Introduction. Clin Cardiol. 2000,31(S1):I1.

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Antiplatelet
Strategies: Evaluating Their Current Role in the Setting of Acute Coronary Syndromes. Clin Cardiol. 2000,31(S1): 12-19.

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Accessing the
Current Role of Platelet Function Testing. Clin Cardiol. 2000,31(S1): 110-I16.

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. The Problem of
Persistent Platelet Activation in Acute Coronary Syndromes and Following Percutaneous Coronary Intervention. Clin Cardiol. 2000,31(S1): 117-
120.


Cardiology


Annual Report AY 2008


Cardiology






Division Chief: Theodore Bass, MD


Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Investigating the
Mechanisms of Hyporesponse to Antiplatelet Approaches. Clin Cardiol. 2000,31(S1): I21-I27.

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Clinical
Considerations with the Use of Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention. Clin Cardiol. 2000,31(S1): I28-
135.

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Antiplatelet
Therapy and Platelet Function Testing: Conclusion. Clin Cardiol. 2000,31(S1):I36.

Suzuki N, Angiolillo DJ, Monteiro C, Shuja S, Futamatsu H, Kawaguchi R, Box LC, Guzman L, Zenni MM, Gilmore PS, Bass TA, Costa MA. Variable
histological and ultrasonic characteristics of restenosis after drug-eluting stents. IntJ Cardiol2008 (in press).

Costa MA, Angiolillo DJ, Tannenbaum M, Driesman M, Chu A, Patterson J, Kuehl W, Battaglia J, Dabbons S, Shamoon F, Flieshman B,
Niederman A, Bass TA. Impact of Stent Deployment Procedural Factors on Long-Term Effectiveness and Safety of Sirolimus-eluting Stents Final
Results of The Multicenter Prospective S.T.L.L.R. Trial. Am J Cardiol 2008 (in press).

Antonios N, Angiolillo DJ, Silliman S. Hypertriglyceridemia and ischemic stroke. European Journal of Neurology. 2008 (in press).

Mansouri V, Lavine SJ. Effect of external constraint on the index of myocardial performance in a canine model of left ventricular dysfunction.
Echocardiography. 2007 Aug;24(7):712-22.

Lavine SJ, and Prcevski P. Modulating Effect of Glycemic Control on Left Ventricular Response to Afterload Stress in Diabetic Canines with Left
Ventricular Dysfunction. JAm CollCardiol 2008, in press

Lavine SJ, Caines A Prediction of Left Ventricular Filling Pressures with Changes in Preload and Afterload. JAm Soc Echo, in press 6/08

Lavine SJ, Caines A. Effect of calcium channel blockade and Angiotensin converting enzyme inhibition on left ventricular systolic and diastolic
function in a canine model of poorly controlled diabetes. JAm Soc Echo, in press June 2008

Lavine SJ and Walsh T. Noninvasive Estimation of LV Filling Pressures in Diastolic Dysfunction can be Predicted by Tricuspid Regurgitation
Velocity. JAm Soc Echo, in press, June 2008.

Angiolillo DJ, Kastrati A, Simon DI. "A Clinical Guide to the Use of Antithrombotic Drugs in Coronary Artery Disease" (Taylor & Francis, UK -
2008)

Angiolillo D.J., Capranzano P, Macaya C. Targeting the diabetic platelet (in A Clinical Guide to the Use of Antithrombotic Drugs in Coronary
Artery Disease; edited by Angiolillo DJ, Kastrati A, Simon DI; Informa Healthcare. 2008; p: 205-210).

Angiolillo D.J, Bernardo E. P2Y12 receptor antagonists: from bench to bedside (in A Clinical Guide to the Use of Antithrombotic Drugs in
Coronary Artery Disease; edited by Angiolillo DJ, Kastrati A, Simon DI; Informa Healthcare. 2008; p:45-52).

Guzman, L; Bass, T. Antithrombotic Treatment in Vein Graft Intervention (in A Clinical Guide to use Antithrombotic Drugs in Coronary Artery
Disease. edited by Angiolillo DJ, Kastrati A, Simon DI; Informa Healthcare. 2008; p: 197-204).

Costa MA, Sabate M, Alfonso F. Stenbt thrombosis in the era of drug eluting stents (in A Clinical Guide to use Antithrombotic Drugs in Coronary
Artery Disease. edited by Angiolillo DJ, Kastrati A, Simon DI; Informa Healthcare. 2008; p: 211-220).

Guzman L., Book: Evidence in Cardiology. 5th Edition. Title: Evidence Based Medicine in Percutaneous Coronary Angioplasty. Editors: C. Tajer,
M.D., H. Doval, M.D.; Publisher Atlante; May 2008 (in press)


HONORS AND AWARDS
Theodore A. Bass, M.D.
University of Florida College of Medicine Exemplary Teacher Award (Jacksonville, June 2008)

Dominick Angiolillo, M.D., Ph.D.
Northwestern Cardiovascular Young Investigators' Forum -Junior Faculty Clinical Research (First Place) (Chicago, November
2007)

University of Florida College of Medicine Researcher/Scholar of the Year (Jacksonville, May 2008)

One of Five Researchers Recognized on behalf of the ITALIAN Government for Italian Researchers who have made major
contributions to Cardiovascular Research (Parma, Italy June 2008)

Luis Guzman, MD
University of Florida College of Medicine Exemplary Teacher Award (Jacksonville, June 2008)


Annual Report AY 2008


Cardiology


Cardiology






Division Chief: Theodore Bass, MD


Steve Hsu, MD
University of Florida College of Medicine Exemplary Teacher Award (Jacksonville, June 2008)

Alan Miller, MD
University of Florida College of Medicine Exemplary Teacher Award (Jacksonville, June 2008)


CLINICAL ACTIVITIES


Inpatient activity AY 07/08
CV In PT admissions 2198
Cardiology discharges
Observations 550

Outpatient activity
Physician clinic visits *9,685
Cardiac ultrasounds 10,230
Cardiac nuclear studies 2,482
EKGs 55,782
Stress tests 3,118
Heart caths ** 2,462
EP procedures *** 508
Device placements 330
Cardiac rehab visits 3,202
*Attending and Fellows
**Cath Only = 1638, Coronary = 656, Peripheral = 168
***Includes: Ablations, Cardioversions, EP's, & Lead Extractions


CONTRACTS AND GRANTS
RESEARCH
Sponsor Date Begun Study
Eli Lilly 6/05 TIMI38
Eli Lilly 7/06 SWAP
Eli Lilly 11/06 TIMI44
HCRI 3/06 Resistor
Medtronic 1/05 Endeavor
Eli Lilly 4/08 TACA
Sanofi-Synthelabo 7/05 Stradivarius
Atra Zeneca 3/07 PLATO
Baxter 7/06 ACT34
Accumetrics 2/08 Clopidogrel Response Study
Molecular Insight 9/07 MIP
Pharmaceuticals
Cordis 3/08 SAPPHIRE WW
Abbott Vascular 7/06 Exact
NHLBI 12/06 Coral
FoxHollow 4/06 Leap
St Jude Medical 9/07 CRT-D
Boston Scientific 9/07 RAPID-RF
Amgen 9/07 RED-HF
St. Jude Medical 9/05 PAS
Norvacrdia/Merck 9/07 PROTECT
CONTRACTS & GRANTS, CARDIOVASCULAR IMAGING CORE LABORATORIES AND BASIC RESEARCH
Sponsor Date Role of Nominee
GSK 2007-2009 Educational Grant

Cordis Japan 2006-2011 Unrestricted Educational Grant, Core Lab


Annual Report AY 2008


Cardiology


Cardiology





Division of Endocrinology, Diabetes and Metabolism


DIVISION OF ENDOCRINOLOGY, DIABETES AND METABOLISM
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Endocrinology, Diabetes and Metabolism had a year of rapid growth and development in all areas of the
academic mission of the University of Florida. Dr. Wehmeier was appointed June 10, 2007 as the Division Chief after Dr. Robert
Lavine served as Interim Chief of the Division of Endocrinology. The most significant advance was ACGME approval of the
Endocrinology Fellowship Training Program which will begin in July 2008. Clinically, major events included expansion of clinical
services and in research, the new research building was inaugurated allowing the Division of Endocrinology to continue
investigations into hormone action. Academically, the division submitted multiple publications and contributed immensely to the
educational component of the University's mission in many training programs at the University of Florida as well as non-
university affiliated health care providers.

Patient care: The division provides inpatient and outpatient consultation for the University of Florida Jacksonville campus
and satellite offices as well as for referring physicians in the Northeast Florida and Southern Georgia regions. Dr. Joe Chehade,
Dr. Mae Sheikh-Ali, and Dr. Kent R. Wehmeier are the core clinical faculty. The division addresses clinical endocrinology
problems related to diabetes mellitus, metabolic syndrome, obesity, pituitary, thyroid, adrenal and sex hormone gland
dysfunction. Patients with metabolic disorders including cholesterol, calcium and metabolic bone diseases such as osteoporosis
and vitamin D deficiency are also evaluated and treated. Thyroid needle biopsy procedures under ultrasound guidance are
offered by the division. The division also coordinates outpatient and inpatient education services that include diabetic
educators. A multidisciplinary approach with the support of neurosurgery, ophthalmology, otolaryngology and radiation oncology
is utilized in the management of patients with pituitary disease.

Education: The most significant event this year was ACGME accreditation with commendation of the Endocrinology Fellowship
in May. The program received a two year provisional accreditation, which will begin in July 2008 with 2 fellows, and will be
under the direction of Dr. Wehmeier. In residency education, Dr. Wehmeier joined the Internal Medicine Core program as
Director of relevant educational programs in endocrinology. He is the primary liaison between the Core Residency Program and
the division, and is a member of the Resident Education Committee. Dr. Joe Chehade and Dr. Mae Sheikh-Ali made major
contributions to the training of the Internal Medicine Core Program residents with didactic presentations, Board review questions
and bedside teaching.

In the educational program of University of Florida medical students, Dr. Chehade and Dr. Wehmeier participated in
preceptoring clinics in endocrinology along with coordinating lectures for the medical students during their third year medicine
clerkship. Dr. Joe Chehade spearheaded the Endocrinology Symposium that was held in Jacksonville this academic year. The
symposium served as an update regarding endocrinology topics for the primary care physician. This meeting was attended by a
broad group of health care providers practicing in the Jacksonville metropolitan area.

Research: Inauguration of the new research building allowed opening of the endocrinology laboratories and research offices at
the facility. Basic science programs in the area of hormone action in oncology and atherosclerosis moved forward. Multiple
grant applications have been submitted to potential funding sources. Active areas of research include endoplasmic recticulum
stress, lipid metabolism, vitamin D signaling and thyroid neoplasia.

LISTING OF FACULTY MEMBERS

Joe Chehade, M.D., Associate Professor
Medical School / Graduation date St. Joseph University School of Medicine, Beirut-Lebanon 1992
Internship/residency and year Staten Island University Hospital 1997
Subspecialty training and year Saint Louis University School of Medicine 1997

Michael Haas, PhD, Research Associate Professor
Graduate School/Graduation date University of Nebraska Medical Center 1991
Post-Graduate Training and year McArdle Laboratory for Cancer Research 1994

Arshag D. Mooradian, M.D., Professor and Department Chairman
Medical School / Graduation date American University of Beirut, Lebanon 1980
Internship/residency and year American University of Beirut, Lebanon 1982
Subspecialty training and year University of Minnesota 1983

Mae Sheikh-Ali, M.D., Assistant Professor
Medical School / Graduation date Damascus University School Medicine, Syria 1999
Internship/residency and year Drexel University College Of Medicine 2005


Division Chief: Kent Wehmeier, MD


Annual Report AY 2008


Endocrinology, Diabetes and Metabolism






Division of Endocrinology, Diabetes and Metabolism Division Chief: Kent Wehmeier, MD


Subspecialty training and year Mayo Clinic, Jacksonville, Florida 2007

Kent Wehmeier, M.D., Associate Professor and Division Chief
Medical School / Graduation date University of Missouri-Columbia 1988
Internship/residency and year Barnes-Jewish Hospital 1991
Subspecialty training and year Saint Louis University School of Medicine 1993

PUBLICATIONS

Albert SG, Oiknine RF, Parseghian S, Mooradian AD, Haas MJ, McPherson T. The effect of glucosamine on Serum HDL cholesterol and
apolipoprotein Al levels in people with diabetes. Diabetes Care Nov; 30:2800-2803, 2007.

Wehmeier KR, Mazza A, Hachem S, Ligaray K, Mooradian AD, Wong NC, Haas MJ. Differential regulation of apopliprotein A-I gene
expression by vitamin D receptor modulators. Biochim Biophys Acta Feb;1780: 264-73, 2008.

Mooradian, AD, Haas, MJ, Wong, NCW, Wehmeier, KR. Obesity-related changes in high-density lipoprotein metabolism. Obesity 16:1152-
1160, 2008.

Sheikh-Ali M, Krishna M, Lloyd R, Smallridge. Predicting the Development of Cushing's Syndrome in Medullary Thyroid Cancer: Utility of
Proopiomelanocortin Messenger Ribonucleic Acid In Situ Hybridization. Thyroid Nov; 17: 631-634, 2007.

Sheikh-Ali M, Karon B, Basu A, Kudva Y, Muller L, Xu J, Schwenk WF and Miles JM. Can serum p-Hydroxybutyrate be used to diagnose diabetic
ketoacidosis? Diabetes Care Apr; 31: pages 643-647, 2008.

Sheikh-Ali M, Aguirre L, Meek S, McNeil B, Keaveny A.P. The incidence and risk factors of new onset diabetes mellitus post liver
transplantation. Accepted for 17h Annual Meeting of the American Association of Clinical Endocrinologists (AACE), May 14-18, 2008. Orlando, FL.
Sheikh-Ali M, Lina Aguirre, Wharen R, Czervionke L, Smallridge, Robert C. TSH-Secreting pituitary microadenoma: Diagnosis by dynamic
contrast enhanced MR scan and octreoscan. Case report. Accepted forl7th Annual Meeting of the American Association of Clinical
Endocrinologists (AACE), May 14-18, 2008. Orlando, FL.

Sheikh-Ali M, Aguirre L, Meek S, McNeil B, Keaveny A.P. the prevalence of abnormal vitamin D and PTH levels in patients with End stage liver
disease. Accepted for the 90th Annual Meeting of the Endocrine Society, June 15-18, 2008. San Francisco, CA.

Chandurkar V, Mooradian AD. Intermittent hyponatremia as a clinical presentation of adrenal insufficiency caused by pituitary adenoma.
Hospital Physician 43: 51-55, 2007.

Bosi E et al Mooradian AD (site PI). Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately
controlled with metformin. Diabetes Care 30: 890- 895, 2007.

Garber AJ et al and Mooradian AD (site PI). Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2
diabetes failing thazolidenedione monotherapy: a randomized, placebo-controlled study. Diabetes, Obesity and Metabolism 9:166-174, 2007.

Goldstein I et al for MOMENTUS Study Investigators. Efficacy and safety of Tadalafil in men with errectile dysfunction with a high prevalence of
comorbid conditions: Results from MOMENTUS: Multiple Observations in Men with Erectile Dysfunction in National Tadalafil Study in the US J.
Sexual Med. 4: 166-175, 2007.

Mooradian AD, Haas MJ. Statins ameliorate glomerular permeability changes in streptozotocin-induced diabetic rats. Am. J. Therap. 14:41-45,
2007.

Albert SG, Obediah J, Parseghian SA, Hurley W, Mooradian AD. Severe insulin resistance associated with subcutaneous amyloid deposition.
Diabetes Research and Clinical Practice 75:374-376, 2007.

Albert SG, Haas MJ, Mooradian AD. Effects of recombinant human growth hormone (rhGH) supplementation on adipokines and C reactive
protein in obese subjects. Growth Hormone & IGF Research 17:19-25, 2007.

Snyder PJ, Biller BM, Zagar A, Jackson I, Arafah BM, Nippoldt TB, Cook DM, Mooradian AD, Kwan A, Scism-Bacon J, Chipman JJ, Hartman ML.
Effect of growth hormone replacement on bone mineral density in adult-onset growth hormone deficiency. J Bone Miner Res. 22:762-770, 2007.

Wylie-Rosett J, Albright AA, Apovian C, Clark NG, Delahanty L, Franz MJ, Hoogwerf B, Kulkarni K, Lichtenstein AH, Mayer-Davis E, Mooradian
AD, Wheeler M. 2006-2007 American Diabetes Association nutrition recommendations: issues for practice translation. J Am Diet Assoc.
107:1296-304, 2007.

Albert SG, Oiknine R, Parseghian S, Mooradian AD, Haas MJ, McPherson T. The effect of glucosamine on serum high density lipoprotein
cholesterol and apolipoprotein AI levels in people with diabetes mellitus. Diabetes Care 30:2800-2803, 2007.

Lowman E, Mooradian AD. Macromelia masquerading as an acromegaloid syndrome in an adult with Klippel-Trenaunay syndrome. Endocrine
Practice. 14:109-111, 2008.

Mooradian AD. Asymptomatic hyperthyroidism in older adults? is it a distinct clinical and laboratory entity? Drugs & Aging 25(5):371-80, 2008.

Annual Report AY 2008 21 Endocrinology, Diabetes and Metabolism






Division of Endocrinology, Diabetes and Metabolism


Wehmeier, KR, Mazza, A, Hachem, S, Ken Ligaray K, Mooradian AD, Wong, NC, Haas MJ. Differential regulation of apolipoprotein A-I gene
Expression by vitamin D receptor modulators Biochim. Biophys. Acta 1780:264-273, 2008.

American Diabetes Association, Bantle JP, Wylie-Rosett J, Albright AL, Apovian CM, Clark NG, Franz MJ, Hoogwerf BJ, Lichtenstein AH, Mayer-
Davis E, Mooradian AD, Wheeler ML. Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes
Association. Diabetes Care. Jan;31 Suppl 1:S61-78, 2008.

Nowak FV, Mooradian AD. Endocrine Function and Dysfunction. Encyclopedia of Gerontology: Age, Aging, and the Aged. (Second Edition) J.
E. Birren (ed); Elsevier Inc. San Diego, CA. Vol. 1; 2007; pp 480-493.
Mooradian AD. Korenman, SG. Endocrinology, in Atlas of Internal Medicine, Eugene Braunwald (ed). Third Edition, Springer, Philadelphia,
2007, pp. 121-179.

Mooradian AD. The effect of nutrients on apolipoprotein AI gene expression. In High Density Lipoproteins. From Basic Biology to Clinical
Aspects, Christopher. J. Fielding (ed), Wiley-VCH, Weinheim2007; 399-423.


CLINICAL ACTIVITIES


Inpatient Activity AY 07/08
Number of Inpatient Admissions 17
Number of Inpatient Consults 310

Outpatient Activity
Clinic Visits 4020
Thyroid Biopsies 87


GRANTS AND CONTRACTS


Endocrinology, Diabetes and Metabolism


Investigator Sponsor/Title Project period Total direct costs
Mooradian AD NHLBI., National Institute of Health, Grant # U01 HL61744-01 "Bypass Angioplasty 3/01-3/08
(Site PI) Revascularization Investigation in type 2 diabetes"
Mooradian AD NIH- National Institute on Aging Small Business Innovation Research Grant 1 R43
(Co- PI) AG028218-01 (SBIR) 2007-2009 "Formulated Phytosterols A New Treatment for Benign
Prostatic Hyperplasia," Protocol No. ZNX 1.003-C.
Mooradian AD Shands/UF CME Grant: Impact of diabetes education on outcome of hospitalized diabetic 2007-2008 $17,500
(PI) patients.
Wehmeier K University of Florida Dean's Fund Resident Research Grant 8/07 -8/08 $8,000
(PI) Effect of vitamin D receptor ligands on apoAI-apoCII gene cluster


Division Chief: Kent Wehmeier, MD


Annual Report AY 2008





Division Chief: Louis Lambiase, MD


DIVISION OF GASTROENTEROLOGY
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Gastroenterology had an outstanding 2006-2007 fiscal year. Two new faculty, Dr. Steve Li and Dr. Samir
Habashi joined us. Dr. Byron Kolts retired after thirty-seven years of service to the University of Florida. Clinically, the Division
saw outpatients at the on-campus Ambulatory Care Center (ACC), Emerson Gastroenterology Clinic (Emerson), Northside Multi-
specialty Clinic (Northside), Shands Jail Clinic, UF Jacksonville Faculty Clinic, VA Clinic in Jacksonville, Duval County Health
Department, Beaches Digestive Clinic, and the Southside Digestive Clinic. Ambulatory motility studies, capsule endoscopy, and
diagnostic breath tests were performed at Emerson. Endoscopy procedures were performed at Shands Jacksonville Medical
Center and the Surgical Associates Surgical Center at Emerson. The research operation saw us acquiring several industry
sponsored grants including one with Dr. Ken Vega as the national Principal Investigator. We presented abstracts at the Florida
Gastroenterologic Society Meeting, the American College of Gastroenterology meeting and at Digestive Disease Week. Members
of the division received local, state and national awards for the research. Dr. Steve Li has opened the first virology lab within the
division in the new research building.

Patient Care: The patient care aspect of the academic mission is pursued by the Division through four University of Florida
clinics, the provision of inpatient consult services at Shands Jacksonville, inpatient and outpatient GI services at Baptist Medical
Center Beaches and St. Luke's Hospital, as well as providing outpatient services at the Jacksonville Veterans Administration
Medical Center, and the Duval County Department of Health. The Division continues to be the leader in Northern Florida in the
treatment of viral hepatitis and staffs a gastrointestinal motility laboratory that is among the most active in the state.

Education: The division was involved in teaching for the residency program. Coordinated by Dr. Ravi Kottoor, the division
conducted resident rotations for inpatient gastroenterology consults and ambulatory gastroenterology. The division taught
residents in morning report, noon resident conference, and internal medicine grand rounds.

The division conducted a Gastroenterology Fellowship Program which consists of two fellows a year for three years. The
program was pleased to continue its 100% board passage rate by previous year's graduates. Work is underway to prepare for
an upcoming accreditation site visit.

Research: Divisional research activities include clinical trials, and giving presentations at regional and national meetings.
Dr. Kenneth Vega received an "Award of Excellence" for submitting the best abstract regarding research in the health on under-
represented minorities at the national Digestive Disease Week meeting in San Diego.
Dr. Ivan Rascon-Aguilar won a fellow research award for his presentation at the Florida Gastroenterologic Society Meeting.


LISTING OF FACULTY MEMBERS

New Faculty
Samir Habashi, M.D., Assistant Professor
Medical School / Graduation date Ain-Shams University, Cairo, Egypt 1985
Internship/residency and year University of Florida Jacksonville 2003
Subspecialty training and year University of Florida Jacksonville 2007

Xiaoyu Li, M.D., Ph.D. Assistant Professor
Medical School / Graduation date Harbin Medical University, Harbin, China 1983
Internship/residency and year Mt Sinai School of Medicine 2004
Subspecialty training and year University of Florida 2007
Graduate School State University of New York 2001

Current Faculty
Louis Lambiase, M.D., M.H.A. Associate Professor and Division Chief
Medical School / Graduation date University of Miami 1987
Internship/residency and year University of Pittsburgh 1990
Subspecialty training and year University of Florida 1992
Graduate School University of North Florida 2006

Robert Bass, M.D., Assistant Professor
Medical School / Graduation date Medical College of Georgia 1988
Internship/residency and year University of South Alabama 1991
Subspecialty training and year University of Florida Jacksonville 1993


Gastroenterology


Annual Report AY 2008


Gastroenterology






Division Chief: Louis Lambiase, MD


Byron Kolts, M.D., Professor
Medical School / Graduation date University of Rochester 1964
Internship/residency and year Dartmouth Medical School/University of Vermont 1967
Subspecialty training and year University of Florida 1972

Ravi Kottoor, M.D., Associate Professor
Medical School / Graduation date Kasturba Medical College, India 1970
Internship/residency and year Ottawa Civic Hospital 1974
Subspecialty training/year Dalhousie University, Canada 1975

Juan Munoz, M.D., Assistant Professor
Medical School / Graduation date Universidada Complutense, Spain 1991
Internship/residency and year University of Florida Jacksonville 2001
Subspecialty training and year University of Florida Jacksonville 2004

Edward Partyka, M.D., Assistant Professor
Medical School / Graduation date Ohio State University 1973
Internship/residency and year Mount Carmel Medical Center 1976
Subspecialty training and year University of Arizona, VA Hospital 1980

Paul Sievert, M.D., Assistant Professor
Medical School / Graduation date University of Miami 1996
Internship/residency and year Medical College of Virginia 1999
Subspecialty training and year University of Florida Jacksonville 2003

Kenneth Vega, M.D., Associate Professor
Medical School / Graduation date Cornell University Medical College 1988
Internship/residency and year Boston University School of Medicine 1991
Subspecialty training and year Temple University Hospital 1995


PUBLICATIONS

Jamal MM, Samarasena JB, Hashemzadeh M, Vega K3. Declining Hospitalization Rate of Esophageal Variceal Bleeding in the United States. Clin
Gastroenterol Hepatol. 2008 May 2.

Reddy SC, Vega K3. Endoscopic diagnosis of chronic severe upper GI bleeding due to helminthic infection. Gastrointest Endosc. 2008
May;67(6):990-2.

Ibegbu E, Relan M, Vega K3. Retrograde jejunoduodenogastric intussusception due to a replacement percutaneous gastrostomy tube
presenting as upper gastrointestinal bleeding. World J Gastroenterol. 2007 Oct 21;13(39):5282-4

Vega KI, Rabaa E, Jamal MM. Lower esophageal sphincter pressure and distal esophageal body function between Hispanic Americans and non-
Hispanic whites are equivalent. J Clin Gastroenterol. 2007 Feb;41(2):141-4

Munoz JC, Habashi S, Corregidor AM, Bass R, Alizadeh M, Gupta R, Lambiase LR, Vega K3. Extraction of hollow gastric foreign bodies by
flexible upper endoscopy assisted by a through-the-scope balloon catheter for anchoring. Gastrointest Endosc. 2008 Mar;67(3):519-21.

Gupta R, Munoz JC, Garg P, Masri G, Nahman NS, Lambiase LR. Mediastinal Pancreatic Pseudocyst-A Case Report and Review of the
Literature. MedGenMed 2007;9(2):8.

Harrison J and Lambiase LR The Improving Efficiency of University Health System Consortium (UHC) Hospitals. Journal of Public Budgeting,
Accounting and Financial Management 2007;19(3)

Lambiase L, Harrison J. The impact of GME on Teaching Hospital Efficiency. Journal of Health Care Finance. 2007;34(1):19-26

Jacobson IM, Brown RS Jr, McCone J, Black M, Albert C, Dragutsky MS, Siddiqui FA, Hargrave T, Kwo PY, Lambiase L, Galler GW, Araya V,
Freilich B, Harvey J, Griffel LH, Brass CA; WIN-R Study Group. Impact of weight-based ribavirin with peginterferon alfa-2b in African Americans
with hepatitis C virus genotype 1. Hepatology 2007; 46(4):982-990.


HONORS AND AWARDS

Kenneth J Vega Excellence in Minority Research DDW 2008


Annual Report AY 2008 Gastroenterology


Gastroenterology


Annual Report AY 2008


Gastroenterology






Division Chief: Louis Lambiase, MD


CLINICAL ACTIVITIES


Inpatient Activity AY 07/08
Number of IP Consults 1447
Shands Jacksonville Inpatient Procedures 1355
Baptist Beaches Inpatient Procedures 125

Outpatient Activity
Clinic Visits 14776
Shands Jacksonville Outpatient Procedures 4613
Jacksonville Beach Surgery Center Outpatient Procedures 708
Jacksonville Surgery Center 1189
Medical Partners Surgery Center 235


GRANTS AND CONTRACTS


Principal Sponsor/Title Project Total Direct
Investigator Period Cost
Lambiase, A Multi-center, Randomized, Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Albuferon'T 08/04- $88,171
Louis R Recombinant Human Albumin-Interferon Alfa Fusion Protein in Combination with Ribavirin in Interferon present
Treatment Experienced Subjects with Chronic Hepatitis C

Lambiase, Comparison of PEG-Intron 1.5 ug/kg/wk Plus REBETOL vs PEG-Intron 1 ug/kg/wk Plus REBETOL vs 11/05- $59,752
Louis R PEGASYS 180 ug/wk PlusCOPEGUS'T in Previously Untreated Adult Subjects with Chronic Hepatitis C Infected present
with Genotype 1

Lambiase, An Extension Protocol to Evaluate the Long-Term Effects of Treatment with Peginterferon Alfa-2a (PEG-IFN)- 10/05 $3,520
Louis R or Interferon-Based Therapies for Patients with Chronic Hepatitis C present

Lambiase, A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of Renzapride in 09/05 $26,895
Louis R Women with Constipation- Predominant Irritable Bowel Syndrome present

Lambiase, A Phase III, Multicenter, Open Label, Extension Study to Evaluate the Long-term Safety of Renzapride 4mg 01/06 $9,054
Louis R Once Daily in Women with Constipation-Predominant Irritable Bowel Syndrome (c-IBS) present

Lambiase, A Randomized, Multicenter, Double Blinded, Phase IV Study Comparing the Safety and Efficacy of Pegasys 05/06- $26,131
Louis R 180ug plus Copegus 1,000 or 1,200 mg to the Currently Approved Combination of Pegasys 180ug plus present
Copegus 800mg in Interferon Naive Patients with Chronic Hepatitis C Genotype 1 virus Infection Co infected
with Human Immuno-deficiency Virus (HIV-1)

Lambiase, A Randomized, Multi-center, Double-Blinded, Phase IV Study Evaluating the Efficacy (as measured by 12/06- $12,654
Louis R Sustained Virological Response) and Safety of 360 mcg. Induction Dosing of Pegasys in Combination with present
Higher Copegus Doses in Treatment-naive Patients with Chronic Hepatitis C Genotype 1 Virus Infection of
High Viral Titer and Baseline Body Weight Greater than or Equal to 85 kg

Lambiase, A Phase 3, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Albumin Interferon Alfa-2b 02/07- $159,186
Louis R (alb-IFN) in Combination with Ribavirin Compared with Peginterferon Alfa-2a (PEGASYS or PEG-IFNa2a) in present
Combination with Ribavirin in Interferon Alfa Naive Subjects with Chronic Hepatitis C Genotype 1

Lambiase, A Phase 3, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Albumin Interferon Alfa-2b 02/07- $ 7,050
Louis R (alb-IFN) in Combination with Ribavirin in Interferon Alfa Naive Subjects with Chronic Hepatitis C Genotype 2 present
or 3

Lambiase, An Open-Label Clinical Study Evaluating the Long Term Safety of ALTU-135 in the Treatment of Patients with 10/07- $8,126
Louis R Exocrine Pancreatic Insufficiency due to Chronic Pancreatitis or Pancreatectomy present

Lambiase, A Randomized, Double-blind, Placebo-controlled Study of AGI-003 (Arverapamil) in the Treatment of Irritable 12/07- $6,213
Louis R BowelSyndrome with Diarrhea (IBS-D) present

Munoz, Juan A Randomized, Double-Blind, Study of GT267-004 Versus Vancomycin, and GT267-004 Versus Metronidazole, 03/05- $23,800
C in Patients with C. Difficile-Associated Diarrhea 04/07

Vega, Comparison of Normal Values of Esophageal 24-hour Acid Exposure Between African American Compared 09/03- $50,666
Kenneth J toNon-Hispanic Whites 03/07

Vega, COPD Patients diagnosed with Gastroesophageal Reflux Disease have Decreased Rates of COPD Exacerbations 06/07- $25,085
Kenneth J After Treatment with High Dose Proton Pump Inhibitor Therapy (Esomeprazole or Lansoprazole) present

Vega, Validation of the GERQ for use in African Americans 01/05- $32,708
Kenneth J present


Gastroenterology


Annual Report AY 2008


Gastroenterology





Division Chief: Linda Edwards, MD


DIVISION OF GENERAL INTERNAL MEDICINE
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division continues a robust inpatient and outpatient practice and is an integral part of the educational experience for the
Internal Medicine residency.

Patient Care: The Division of General Internal Medicine is comprised of 14 members who are board certified in Internal
Medicine. Their clinical care includes: the provision of inpatient care as the attending for the four inpatient teaching services,
outpatient care at three locations: the ACC, Faculty Clinic and the UF Multispecialty Clinic on Emerson, an inpatient Internal
Medicine consultation service and medical evaluation of patients admitted to the Psychiatry service. The division has
experienced significant growth in its outpatient practice as the newer physicians in the group have established themselves as
excellent clinicians. One of the highlights of the outpatient practice is the JaxHATS (Jacksonville Health and Transition Services)
Clinics held on Tuesday and Thursday mornings. Dr. Edwards, in conjunction with Dr. Wood, a general pediatrician, have
established this clinic that provides a medical home for adolescents and young adults with special health care needs who are
transitioning from their pediatricians to adult providers.

Education: The Division provides faculty supervision of residents on the four general internal medicine inpatient teaching
services, inpatient medicine consultation service and geriatrics. The division also provides faculty supervision and mentoring of
all categorical medicine residents in their outpatient continuity practice and urgent care clinics.

Dr. Sottile conducted her third faculty development seminar for several members of the department in 2007. The seminar ran
for 8 weeks for a total of 16 hours. The topic was "Clinical Teaching". She conducted the first seminar in the spring of 2006
with all faculty members of the Division of GIM participating. Dr. Sottile also serves as a facilitator and is the co-developer of the
"Teaching Residents to Teach"-a 6-8 hour intradepartmental seminar offered each year at the University of Florida Health
Science Center/Jacksonville. Dr. Arpitha Ketty also serves as a facilitator for the "Teaching Residents to Teach" seminar.

Drs. Arpitha Ketty and Olga Petrucelli are Associate Program Directors for the Internal Medicine Residency Program. Drs.
Alexandraki and Palacio serve as Associate Clerkship Director and Clerkship Director for medical students from Gainesville who
rotate on the Internal Medicine service (inpatient and outpatient). Dr. Jeff House coordinates monthly M&M/QA for the training
program. Drs. Alexandraki, House and Meenrajan also serve as key clinical faculty for the Core Training Program in Internal
Medicine.

Drs. Edwards, House, Ketty, Petrucelli and Sottile serve on the House Staff Evaluation Committee. Drs. Alexandraki, Edwards,
House, Ketty, Meenrajan and Petrucelli also serve on the Resident Education Committee. All members of the division have
participated in and/or presented at the noon conference core curriculum series held daily as well as the Friday afternoon
ambulatory didactic sessions and Board review.

Research: Research in the division continues to focus on continuing medical education, clinical research, and faculty
facilitation of resident research projects. Drs. House, Ketty and Petrucelli worked with resident recipients of the Dean's Fund
Research Awards. Dr. House has several clinical studies ongoing and Drs. Alexandraki and Palacio are evaluating the Diabetes
Education program at UF and Shands.

LISTING OF FACULTY MEMBERS

Irene Alexandraki, M.D., Assistant Professor
Medical School / Graduation date University of Athens, Greece 1989
Internship/residency and year Hahnemann University Hospital 1998
Subspecialty training and year Baylor College of Medicine (Infectious Disease) 2001

Linda Edwards, M.D., Associate Professor and Division Chief
Medical School / Graduation date East Carolina University 1981
Internship/residency and year Jacksonville Health Education Programs 1985

Malcolm Foster, M.D., Professor
Medical School / Graduation date Bowman Gray School of Medicine 1963
Internship/residency and year University of Florida, Gainesville 1966
Subspecialty training and year University of Florida, Gainesville (Infectious Disease) 1967

Alan Halperin, M.D., Professor
Medical School / Graduation date University of Kansas 1971
Internship/residency and year University of Wisconsin 1974


General Internal Medicine


Annual Report AY 2008


General Internal Medicine






Division Chief: Linda Edwards, MD


Jeffrey House, D.O., Assistant Professor
Medical School / Graduation date Nova Southeastern College of Osteopathic Medicine 1997
Internship/residency and year University of Florida Jacksonville 2001

Arpitha Ketty, M.D., Assistant Professor
Medical School / Graduation date University of Southern California, Los Angeles 1999
Internship/residency and year University of California, Davis 2002

Ghania Masri, M.D., Assistant Professor
Medical School / Graduation date Damascus University, Syria 1989
Internship and year Cleveland Clinic Foundation 1992
Residency and year Case Western Reserve University 1994

Senthil Meenrajan, M.D. M.B.A, Assistant Professor
Medical School / Graduation date Madras Medical College, India 1997
Internship/residency and year Robert Packer Hospital 2004
Subspecialty training and year Oregon Health Sciences University (Geriatric Medicine) 2005
Post-graduate training and year Canyon College (MBA: Healthcare Administration) 2004

Carlos Palacio, M.D., M.P.H., Assistant Professor
Medical School / Graduation date University of Miami 1993
Internship/residency and year University of Florida, Jacksonville 1997
Post-graduate training and year University of North Florida (MPH, Master of Public Health) 2007

Olga Petrucelli, M.D., Assistant Professor
Medical School / Graduation date University of South Florida 1996
Internship/residency and year University of Chicago Hospital 1999

James Phillips, M.D., Assistant Professor
Medical School / Graduation date St. George's University, West Indies 2001
Internship/residency and year University of Florida, Jacksonville 2005

Pramod Reddy, M.D., Assistant Professor
Medical School / Graduation date Sri Dev Raj Urs Medical College, India 1992
Internship/residency and year Stony Brook University Hospital 2000

Manish Relan, M.D., Assistant Professor
Medical School / Graduation date Armed Forces Medical College, India 1995
Internship and year Brookdale University Hospital 2000
Residency and year Scranton Temple Residency Program 2002

Elisa Sottile, M.D., Assistant Professor
Medical School / Graduation date Temple University School of Medicine 1993
Internship/residency and year University of Pennsylvania 1997


PUBLICATIONS

Alexandraki, I Contributing author "Community Acquired Pneumonia" chapter of the textbook "Internal Medicine Essentials for Clerkship
Students", 3d edition, ACP- Clerkship Directors in Internal Medicine, 2007, Chapter 53, pages 177-179

Alexandraki, I Contributing author "Urinary Tract Infectiorn chapter of the textbook "Internal Medicine Essentials for Clerkship Students", 3r
edition, ACP-Clerkship Directors in Internal Medicine, 2007, Chapter 48, pages 162-164

Alexandraki I, Department of Medicine, University of Florida College of Medicine-Jacksonville (2008). 48-year-old woman with HIV- Ms. Hunt.
In SIMPLE: Simulated Internal Medicine Patient Learning Experience [Internet], eds. Berman and Fall, Institute for Innovative Technology In
Medical Education, Lebanon, NH. http://www.simplecases.orq.

Palacio C, Department of Medicine, University of Florida College of Medicine-Jacksonville (2008). 65-year old woman-Mrs Thompson. In
SIMPLE: Simulated Internal Medicine Patient Learning Experience [Internet], eds. Berman and Fall, Institute for Innovative Technology In
Medical Education, Lebanon, NH. http://www.simplecases.ora.

Hepatitis C viral load and the risk of bacteremia in hemodialysis patients with Vascular Catheters, S Reddy, R Zaiden, R Sullivan, N Niak, I
Alexandraki, NS Nahman Jr. Presented, Southern AFMR. JInvestMed, 55:S308, 2007


General Internal Medicine


Annual Report AY 2008


General Internal Medicine






Division Chief: Linda Edwards, MD


Otis W. Brawley, MD; Llewellyn J. Cornelius, PhD, LCSW; Linda R. Edwards, MD; Vanessa Northington Gamble, MD, PhD; Bettye L. Green,
RN; Charles Inturrisi, PhD; Andra H. James, MD, MPH; Danielle Laraque, MD; Magda Mendez, MD; Carolyn J. Montoya, RN, MSN, CPNP; Brad H.
Pollock, MPH, PhD; Lawrence Robinson, MD, MPH; Aaron P. Scholnik, MD; and Melissa Schori, MD, MBA National Institutes of Health
Consensus Development Conference Statement: Hydroxyurea Treatment for Sickle Cell Disease Annals of Internal Medicine 2008; 148; 932-8.

Jeffrey House, DO, FACP and Alan K. Halperin, MD, Guest Editors, "Outcomes of Surgical Patients Improve with Perioperative Assessment
and Postoperative Management", Northeast Florida Medicine 2008; 59:10-13.

Jeffery House, DO, FACP,"Perioperative Evaluation and Management of the Patient with Suspected Coronary Artery Disease", Northeast
Florida Medicine 2008; 59:14-18.

Praveen Garg, MD, Jeffrey House, DO, FACP,_"Management of Anticoagulation in the Perioperative Period", Northeast Florida Medicine 2008:
59:28-30.

Masri, Ghania MD; Bledsoe, Kristi PharmD; Palacio, Carlos MD. Characteristics of Patients Prescribed Angiotensin Converting Enzyme
Inhibitors, Angiotensin Receptor Blockers, or the Combination at an Urban Medical Center. Medscape General Medicine. 2007; 9(4):40

Relan M, Kancha RK; Perioperative Assessment and management of patient with Pulmonary Disease. Northeast Florida Medicine Journal; 2008
Vol 59, (1)

Kancha RK, Relan M; Perioperative Assessment and management of patient with Diabetes. Northeast Florida Medicine Journal; 2008 Vol 59,
(1)

Gina Chacon MD, David J. Wolfson MD, Carlos Palacio MD, MPH, FACP, and Sinha A. Animesh MD, PhD, "Darier's Disease: A Commonly
Misdiagnosed Cutaneous Disorder", Journal of Drugs in Dermatology, April 2008; 7(4):19-22.


HONORS AND AWARDS


Irene Alexandraki, M.D.









Linda Edwards, M.D.





Malcolm Foster, M.D.





Alan Halperin, M.D.

Jeff House, D.O.


Arpitha Ketty, M.D.


Ghania Masri, M.D.

Senthil Meenrajan, M.D.


UF College of Medicine's Excellence in Student Education Award 2008
Outstanding Clinical Year Instructor UF Physician Assistant Program 2008
University of Florida Exemplary Teacher Award 2008
Master Educators in Medical Education 2008
Peer Reviewer Journal of General Internal Medicine
Peer Reviewer Journal of Medical Education
Reviewer National Abstract Competition, ACP 2007, 2008
Judge National Poster Finals, ACP Annual Meeting 2007, 2008

Elected Member and Vice-President, Faculty Council HSC/Jacksonville
Member, Executive Committee, UF Self-Insurance Program
NIH Consensus Panel Member "Hydroxyurea Treatment for Sickle Cell Anemia" February 25-
28, 2008
University of Florida Exemplary Teacher Award 2008

Governor, Florida Chapter of the American College of Physicians
Treasurer, Board of Directors, Duval County Medical Society
Board of Directors, ACP Foundation, Vice-Chairman
Board of Directors, Florida Georgia Blood Alliance
University of Florida Exemplary Teacher Award 2008

Chair, Institutional Review Board, UF & SJMC

Chair, Medical Performance Improvement Committee
UF and Shands Jacksonville Medical Center

Master Educators in Medical Education 2008
University of Florida Exemplary Teacher Award 2008

University of Florida Exemplary Teacher Award 2008

University of Florida Exemplary Teacher Award 2008
DCMS representative- FMA's Health, Education and
Public Policy Committee
Duval County Medical Society
Journals and Communication Committee
Homeland Security, Bioterrorism and


Annual Report AY 2008 General Internal Medicine


General Internal Medicine


Annual Report AY 2008


General Internal Medicine





Division Chief: Linda Edwards, MD


Carlos Palacio, M.D.


Olga Petrucelli, M.D.


Elisa Sottile, M.D.


Emergency Preparedness Committee
Legislative Committee
Chair of Elder Task Force: Shands Jacksonville

Vice-Chair, Institutional Review Board
University of Florida Exemplary Teacher Award 2008

Master Educators in Medical Education 2008
University of Florida Exemplary Teacher Award 2008

University of Florida Exemplary Teacher Award 2008


CLINICAL ACTIVITIES


Inpatient Activity AY 07/08
Numbers of Inpatient Admissions 3983
Inpatient Days 20576
Average length of stay 5.16
Number of OBU Admissions 1127
Number of SNU Admissions 318
Number of IP Consults 1569

Outpatient Activity
Clinic Visits 14566


Annual Report AY 2008 General Internal Medicine


General Internal Medicine


Annual Report AY 2008


General Internal Medicine





Interim Division Chief: Fauzia Rana, MD


DIVISION OF HEMATOLOGY & MEDICAL ONCOLOGY
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Oncology continued its clinical and academic missions. The division maintains an ACGME accredited Oncology
fellowship training program and actively participates in training internal medicine residents and medical students in inpatient
and outpatient settings. The division continues to expand multi-disciplinary clinics and has added the Thoracic Oncology Multi-
Disciplinary Clinic. There has been a significant improvement in patient convenience. Dr. Fauzia Rana started the first multi-
modality Sickle Cell Clinic at the C.B. McIntosh Center with Dr. Gary Reisfield and Dr. Akram Khan. Dr. Rana, with the help of
tumor registry, initiated and conducted the first Breast Cancer Screening program at the Proton Therapy Institute. Dr Rana also
organized two public awareness events, one at the Islamic Center and another at the Brooks Health and Fitness Center. These
events were a great success and we are looking forward to providing this free education each year.

Each member of the division has a strong role in division activities. Dr. Rana is Interim Chief of Hematology/Oncology and Chair
of the Cancer Committee. She also initiated the first Breast Cancer Neoadjuvant protocol. Dr. Pham continues his efforts in the
Thoracic Oncology Program and is on the Quality Improvement Committee. He also works with the Proton Therapy Institute in
collaboration of patient care. We have been successful in hiring Dr. Janet Hosenpud who arrived in July 2007 as the Fellowship
Director. Dr. Hosenpud continues to work closely with the education of the fellows.

Patient care: The division continues to work closely with hematology-oncology leadership, and central administration of the
UF College of Medicine Gainesville, to coordinate the divisional mission with growth and development of the Proton Therapy
Institute. It is anticipated that when at full capacity, the facility will result in a 30-50% increase in inpatient and outpatient
activity. This year we have already had a 21% increase in analytic cases data received from Tumor Registry.

Education: The division continues to support the Internal Medicine Residency Program through facilitation of morning report
and noon conference core curriculum. The division offers a consult experience in medical oncology to residents at all training
levels. We have a weekly didactic lecture series that gives fellows the opportunity to present cases to the faculty. Continuing
support of education to division fellows, we have a monthly Journal Club that generates discussion on various oncology related
topics throughout the year. There is a quarterly city wide joint conference between the University of Florida and Mayo Clinic of
Jacksonville. This opportunity allows the fellows to present unusual cases. The fellowship in medical oncology continues to
prosper with all positions filled for July 2008 and 2009.

Research: The Division is currently engaged in 14 clinical hematology/oncology trials. There were 168 subjects pre-screened
for the Breast Clinic and 918 subjects pre-screened for the TOPS Clinic. There were a total of 1086 patients pre-screened for all
of the clinical trials from July 2007 through June 2008. We now have a total of 9 patients currently enrolled in clinical trials.

LISTING OF FACULTY MEMBERS

New Faculty
Janet Hosenpud, MD, Assistant Professor
Medical School / Graduation date University of Washington 1979
Internship/residency and year Medical College of Wisconsin 1980
Subspecialty training and year Oregon Health Sciences University 1982

Current Faculty
Fauzia Rana, MD, Interim Chief and Assistant Professor
Medical School / Graduation date Fatima Jinnah Medical College 1982
Internship/residency and year University of Rochester New York 1990
Subspecialty training and year Dana Farber Deaconess Hospital/Harvard 1993

Dat Pham, MD Assistant Professor
Medical School / Graduation date University of Florida 1997
Internship/residency and year University of Florida Jacksonville 2000
Subspecialty training and year University of Florida Jacksonville 2002

PUBLICATIONS

Gynecologic Oncology Dat C. Pham, M.D. Troy H. Guthrie, M.D. and Boniface Ndubisi, M.D.: HIV- Associated Primary Cervical Non-Hodgkin's
Lymphoma and Tow other Cases of primary Pelvic Non-Hodgkin's Lymphoma [90(1):204-6] 2003

American Journal of Hematology Dat C. Pham, M.D. Troy H. Guthrie, Bruce Villas, Elane Salazar Refractory idiopathic Pure Red Cell Aplasia
Complicated by Immune Thrombocytopenia Successfully Treated with Subcutaneous Alemtuzmab. Case publication January 2008
DOI:10.1002/ajh.21155 Jan 29 2008


Hematology/Oncology


Annual Report AY 2008


Hematology/Oncology






Interim Division Chief: Fauzia Rana, MD


Nikesh Jasani, M.D., Peyman Salimi-Tari,M.D., Fauzia Rana,M.D. Complete Remission Of Metastatic Ewing's Sarcoma/ Primitive
Neuroectodermal Tumor With Standard Chemotherapy pending publication Community Oncology, vol 4 number 9 September 2007

Comparing aromatase inhibitors and tamoxifen as neoadjuvant therapy for breast cancer- Fauzia Rana, M.D.; Shalin Shah, M.D. Community
Oncology, vol 5 number 2 February 2008

Fauzia Rana, M.D., Praveen Garg, M.D., Anticoagulation management in hospitalized patients, NEFJM February 2008

Jasani N, Mohammed K, Fauzia Rana, M.D. HIV-associated Lymphoma. Consultant 2008; 48:349.

HONORS AND AWARDS

Fauzia Rana, MD Fellowship Award, 2007
Fauzia Rana, MD Garrison Research Professor, 2007
Fauzia Rana, MD Southern Medical Association, 2008
Fauzia Rana, MD Breast Cancer Research, 2008
Fauzia Rana, MD Master in Medical Education, 2008

CLINICAL ACTIVITIES


Inpatient Activity AY 07/08
Numbers of Inpatient Admissions 313
Inpatient Days 2082
Average length of stay 6.65
Number of OBU Admissions 21
Number of IP Consults 328

Outpatient Activity
Clinic Visits 5623


CONTRACTS AND GRANTS


Principal Sponsor/Title Project Period Total Direct
Investigator Cost
Pham, Dat Phase III Trial, Bones Mets-Advanced Cancer (Excluding Breast and Prostate Cancer) or Multiple Myeloma 07/07-06/08 $0.00

Pham, Dat Phase III Trial, Breakthrough Cancer Pain in Subjects taking opoids 07/07-06/08 $16056

Pham, Dat Phase III Trial, Breakthrough Cancer Pain in Subjects taking opoids long term 07/07-06/08 $1200

Pham, Dat Phase II Study of Continued Immunotherapy with FavId (Id-KLH) and GM-CSF in Patients with Stable or 07/07-06/08 $1200
Responding Grade 1 or 2 Follicular B-Cell Lymphomas

Pham, Dat Phase III Trial, Melanoma Stage III or IV 07/07-06/08 $0.00

Pham, Dat Hyperuricemia Plasma Uric Acid Management 07/07-06/08

Pham, Dat Phase I/II, Lung NCSLC Relapses or Refractory 07/07-06/08 $0.00

Pham, Dat Phase III Study of the treatment of Subjects with Chronic Phase Philadelphia Chromosome Positive 07/07-06/08 $0.00
Chronic Myeloid Leukemia

Pham, Dat Phase III Study to access the efficacy of the recMage-A3+AS15 Antigen-Specific Cancer Immuno- 07/07-06/08 $0.00
therapeutic as adjuvant therapy in patients with respectable MAGE-A3-positive non-small cell lung cancer.

Pham, Dat Phase II/III Study in the First-Line Treatment of Advanced Transitional Cell Carcinoma (TCC) of the 07/07-06/08 $0.00
Urothelium

Rana, Fauzia A phase ii trial of preoperative capecitabine plus cisplatinum in early stage er negative, pr negative, her- 07/07-06/08 $10000
2 negative breast cancer

Rana, Fauzia Phase II, MDS Indication Thrombocytopenia associated with lenalidomide therapy in MDS 07/07-06/08 $2000

Rana, Fauzia Phase II, MDS Indication Thrombocytopenia associated with hypomethylating agent therapy in MDS 07/07-06/08 $37166

Rana, Fauzia Examination of PNH, by Level of CD 59 pm RBC and WBC in bone marrow failure syndrome 07/07-06/08 $2000


Hematology/Oncology


Annual Report AY 2008


Hematology/Oncology






Interim Division Chief: Fauzia Rana, MD


Annual Report AY 2008


Hematology/Oncology


Hematology/Oncology





Division Chief: Jeff House, DO


DIVISION OF HOSPITAL MEDICINE
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The fiscal year of 2008 proved to be another year of growth and evolution for the Division of Hospital Medicine. The program's
mission still remains to provide quality acute and subacute inpatient care. To achieve this, the program has continued to refine
its practice model as well as its staffing and scheduling protocols.

As in previous years, the inpatient census continued to expand. In order to meet the ever-growing inpatient care demands, the
division began to assertively recruit new physicians. Although four new physicians joined this past year, the division did not
increase in size due to expected attrition. Recruiting efforts have resulted in 7 new physicians joining the division for the next
fiscal year.

Although patient care continues to dominate the division's activities, there have been areas of tremendous growth in education,
scholarly activity and administrative affairs. In research, the division has continued to make strides and produced more
publications than any preceding year.

This year, the division was successful in recruiting its first full time administrator. With her assistance, the division was better
able to define and address key implementation and operational issues relevant to the program. New projects such as
scheduling and clinician report cards were developed. She was also integral in developing the program's monthly newsletter.

Patient care. The Division of Hospital Medicine provides care for one quarter of all inpatient admissions for Shands Hospital-
Jacksonville and, for fiscal year 2008, the division carried an average daily census of approximately 130 patients. This Division
routinely cares for more hospitalized patients than any other service. In addition to providing care to the city's underserved, the
Hospital Medicine Division also provided care to Humana Medicare patients, University of Florida satellite offices and overflow
patients from the teaching services. On occasion, the hospitalists provide assistance to Cardiology when its services are maxed.
The Division of Hospital Medicine provides in-house 24 hour care which is vital to providing quality health care for nightly
admissions and cross coverage issues.

With such high patient care demands, the division made numerous operational adjustments to address potential quality
concerns. As previously mentioned, an aggressive recruitment strategy was one of the first steps in developing the program.
This included not only physicians but ancillary support staff as well. The division has established a geographical, team-oriented
approach to provide more efficient care. Call schedules have been adjusted in order to provide better patient continuity. The
division has also incorporated a dedicated admitting and rounding services. In the spring of 2008, the Division of Hospital
Medicine incorporated a new team approach with case management in order to provide more efficient health care, better
patient satisfaction and shorten length of stay. This new system of pairing a clinician with a specific case manager improved
communication among the staff. Preliminary data has already shown an improvement in length of stay.

In addition to direct patient care, the division also participates in a number a number of administrative activities that greatly
affect patient care. These include the Med Safety Committee, Throughput Committee, Medical Performance Improvement
Committee, and Faculty Council.

Education. Traditionally, the Division of Hospital Medicine has not been directly involved with the educational mission of the
Internal Medicine Residency. However, the division plays a critical role in the health and viability of the inpatient teaching
services. The Hospital Medicine service continues to be the buffer that allows the Internal Medicine Residency Program to
comply with Residency Review Committee rules regarding patient care and duty hours. The hospital medicine staff is also
responsible for monitoring procedures performed by residents at night. Other members of the division participate in medical
student didactic sessions on a regular basis.

Fiscal Year 2008 was marked with the division's first successful elective in hospital medicine. This one-on-one Hospital Medicine
rotation, designed for 3rd year residents, was complete with a written curriculum and didactic sessions on advanced topics such
as palliative care, insurance, and billing.

Dr. House has been intimately involved in the residency program. He is also a member of the internal medicine faculty and he
serves in many facets of resident education. These duties include attending Resident Continuity Clinic, ward services, lecturing
at core conferences and morning report. He also participates in night float rounds on a regular basis. In addition to these
duties, Dr. House is the Director of Clinical Quality Improvement for the residency program and the proctor for the College of
Medicine's monthly Morbidity and Mortality Conference. Lastly, Dr. House is also a member of the Resident Education
Committee and Key Clinical Faculty.


Annual Report AY 2008


Hospital Medicine


Hospital Medicine





Division Chief: Jeff House, DO


In the upcoming year, the division has devised plans to expand their educational role by periodically serving as ward attending
on the inpatient teaching services. Hospital Medicine Journal Club is now well established and is conducted on a monthly basis.
The Hospital Medicine Division also participates in the monthly Morbidity and Mortality conference.

Research. Since the Division of Hospital Medicine is primarily focused on the inpatient care service, this previously has not been
an area of emphasis for the division. In spite of the lack of emphasis on research and scholarly activity, this has been the most
successful year in the program's history in terms of publications. The division recently submitted (in conjunction with Internal
Medicine) a compilation of review articles centered on perioperative medicine. This was published in the spring 2008 Northeast
Florida Medicine Journal.

As in previous years, the division is participating in the Joint Commission of Accredited Healthcare Organizations (JCAHO) core
measures surrounding community acquired pneumonia and congestive heart failure. There are 2 faculty (Drs Garg and House)
who are currently members of the Medical Performance Improvement Committee. Dr. Garg is the Physician Champion for
community acquired pneumonia.

LISTING OF FACULTY MEMBERS

New Faculty

Anna Ayvazyan, M.D., Assistant Professor
Medical School / Graduation date Yerevan State Medical University, Armenia 1995
Internship/residency and year University of Florida Jacksonville (Family Practice) 2007

Sann Yin Htoo M.D., Assistant Professor
Medical School / Graduation date Institue of Medicine, Myanmar 2002
Internship/residency and year Brooklyn Hospital Center 2007

Sanjay Mughal, M.D., Assistant Professor
Medical School / Graduation date Government Medical College, India 1989
Internship/residency and year Maimonides Medical Center 2002
Subspecialty training and year Oregon Health Services University (Geriatric Medicine) 2003

Wilfredo Sanchez, M.D., Assistant Professor
Medical School / Graduation date Ponce School of Medicine, Puerto Rico 2002
Internship/residency and year University of Florida Jacksonville 2005
Subspecialty training and year University of Florida Jacksonville (Infectious Disease) 2007

Current Faculty
Nonette Asistores, M.D., Assistant Professor
Medical School / Graduation date De La Salle University, Phillipines 1986
Internship/residency and year University of Florida Jacksonville (Family Practice) 2004

Arshia Cottey, M.D., Assistant Professor
Medical School / Graduation date Dow Medical College, Pakistan 1993
Internship/residency and year University of Florida Jacksonville 2001

Praveen Garg, M.D., Assistant Professor
Medical School / Graduation date University of Delhi, India 1998
Internship/residency and year University of Rochester 2006

Jeff House, D.O., Assistant Professor and Division Chief
Medical School / Graduation date Nova Southeastern College of Osteopathic Medicine 1997
Internship/residency and year University of Florida Jacksonville 2001

Ravi Kancha, M.D., Ph.D., Assistant Professor
Medical School / Graduation date Ross University Medical School 2002
Internship/residency and year Drexel University College of Medicine 2004
Internship/residency and year George Washington University Hospital 2007
Postgraduate training and year Osmania University (PhD Biochemistry) 1991

Angelika Kharrazi, M.D., Assistant Professor
Medical School / Graduation date Saba University School of Medicine, Netherlands 2000
Internship/residency and year University of Florida Jacksonville (Family Practice) 2006


Annual Report AY 2008


Hospital Medicine


Hospital Medicine






Division Chief: Jeff House, DO


Vijay Konda, M.D., Assistant Professor
Medical School / Graduation date Gandhi Medical College, India
Internship and year Weiss Memorial Hospital

Senthil Meenrajan, M.D. M.B.A, Assistant Professor
Medical School / Graduation date Madras Medical College, India
Internship/residency and year Robert Packer Hospital


Saw Po, M.D., Assistant Professor
Medical School / Graduation date
Internship/residency and year


(anyin State General Hospital, Myanmar
University of Florida, Jacksonville


PUBLICATIONS

Chisholm S, Gummadi B, House J, Vega K, Sandostatin causing reversible thrombocytopenia. European Journal of Gastroenterology &
Hepatology. Accepted

House, "Perioperative Evaluation and Management of the Patient with Suspected Coronary Artery Disease", Northeast Florida Medicine 2008;
59:14-18.

Gara P. House J. "Management of Anticoagulation in the Perioperative Period", Northeast Florida Medicine 2008: 59:28-30.

Shrivastava R, Khan A, Jeevanantham V, Nautiyal A, Garq P, Reddy PC. Control of Cardiovascular Risk Factors and Use of Aspirin in Diabetic
Patients Remain Elusive. South Med J. 2008 May 7. [Epub ahead of print] PMID: 18475221 [PubMed as supplied by publisher]

Ammar H, Brown SH, Malani A, Sheth HK, Sollars EG, Zhou SX, Gupta C, Muahal S. A case of paraneoplastic cerebellar ataxia secondary to
renal cell carcinoma. South Med J. 2008 May;101 (5):556-7. PMID: 18414160 [PubMed in process]

Kancha. R Relan M. "Perioperative Assessment and Management of the Patient with Diabetes", Northeast Florida Medicine 2008: 59:23-27.


CLINICAL ACTIVITIES


Inpatient Activity AY 07/08
Inpatient Admissions 5170
Inpatient Days 32643
Average Length of Stay 6.31
Number of OBU Admissions 1925


CONTRACTS AND GRANTS


Principal Sponsor/Title Project Period Total Direct
Investigator Costs
Pulido D, University of Florida Dean's Fund Resident Research Grant/ EKG screening criteria for 5/07-8/08 $5,000
House J preparticiatition athletic screening


Annual Report AY 2008


2000
2006


1997
2004


1987
2001


Hospital Medicine


Hospital Medicine





Division Chief: Michael Sands, MD


DIVISION OF INFECTIOUS DISEASES
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Infectious Diseases has continued its clinical and academic missions during this past year. A full staffing
complement was maintained during this academic year. The division is currently comprised of 6 infectious diseases consultants
all of whom are dually boarded in internal medicine and infectious diseases, 1 Nurse research coordinator and 1 travel medicine
nurse. The division provides clinical consultation in infectious diseases at the Shands Hospital/Jacksonville, Hospital Infection
Control direction of Shands Hospital, transplantation infectious diseases consultation at Shands, outpatient travel and tropical
medicine services, outpatient infectious diseases consultation, and clinical infectious diseases research. The Division maintains
an ACGME accredited Infectious Diseases Fellowship Training Program and actively participates in the training of internal
medicine residents and medical students in inpatient and outpatient infectious diseases. The division has a major contract with
the Duval County Health Department (DCHD) to provide professional consultation and programmatic direction for the HIV/AIDS,
TB and STD Programs and clinical care to the counties' HIV/AIDS, TB and STD patients in the DCHD specialty clinics. This
contract funds 3.4 FTE of the 5.3 FTE of the division's ID physician time.

Each member of the division has a strong administrative role in division activities. Dr. Sands is currently the University ID
Division Chief, Medical Director of Communicable Diseases for Duval County Health Department and ID Division Fellowship
Program Director. Dr. Vandevelde directs the Travel Medicine section. Dr. Guzman is the Chairperson and Director of Hospital
Infection Control for Shands Hospital, the Division Research Director and coordinates resident and student subspecialty
education. Dr. Mitchell-Samon is the Director of the HIV section. Dr. Bailey is the Director of the STD section, oversees the
Refugee Health section, is the Associate Fellowship Program Director and the consultative liaison for infections in solid organ
transplantation. Dr. Lauer is the Chief of the TB section.

Patient care:
University ID Division inpatient and hospital based activity
The division provides full time infectious consultation throughout the Shands/Jacksonville Hospital system. During the 2007-
2008 academic year, the division performed over 700 inpatient infectious diseases consultations with subsequent follow-up at
Shands Hospital.

Outpatient services
The division offers outpatient ID consultation by referral in its clinic. Travel medicine services are provided daily for overseas
travelers. 850 travel patients have been seen between July 1, 2007 May 31, 2008.

An outpatient ID Consultative Clinic run by Dr. Vandevelde is conducted two half days a week.

The division provides professional and administrative oversight and care for the HIV/AIDS, TB, STD and refugee screening
clinical services for the DCHD specialty clinics. In the 10 month period July 1, 2007 May 31, 2008, ID division physicians
delivered or oversighted the care for over 2,000 HIV/AIDS patients, 4,400 STD visits, 716 refugee visits and over 650 TB visits
at DCHD specialty clinics.

Education:
Grand Rounds: The division actively participates in presenting at Medical Grand Rounds and are regular attendees.

Fellowship Training: The division maintains an ACGME accredited fellowship in infectious diseases with one fellow for each of
the 2 clinical fellowship years.

Resident Training: Division faculty are regular resident morning report attendees, conduct the ID noon core curriculum
conferences, ID consultation teaching rounds, outpatient HIV/AIDS continuity clinics, and resident ID board review sessions.

Medical Student Education: Dr. Guzman presents the HIV/AIDS core content conference for UF medical students by
teleconference with UF Gainesville. Medical student rotate on the infectious consultative service.

ID Division Conference Schedule: The division maintains a full conferencing schedule with ongoing meetings Monday, Thursday
and Friday noon. Conference topics include: regularly scheduled cases conferences; ID Mandell text book board reviews; ID
core topics review utilizing the Chicago Board Review Course; Infectious Diseases topical guidelines and evidence based
medicine conferences: monthly journal club; HIV topical reviews; monthly TB cases and topical reviews; monthly research
conferences; travel and tropical medicine conferences; transplantation ID conferences; and monthly Med/Peds ID joint
conference.

Research: Drs Guzman and Bailey serve as members of the University of Florida/Jacksonville Institutional Review Board.


Annual Report AY 2008


Infectious Diseases


Infectious Diseases






Division Chief: Michael Sands, MD


The division is responsible for performance of components of federal and state categorical grants awarded to the DCHD for TB,
HIV, refugee and STD care and epidemiologic services. These grants are in excess of $6.5 million. Additionally the division has
been instrumental in acquiring and directing a federal Ryan White Title 3 Grant of $300,000 annually for improved community
based access to care, that provides HIV/AIDS care to 250 indigent patients not otherwise brought into care or previously lost
from case.

LISTING OF FACULTY MEMBERS

Michael Sands, MD, MPH&TM, FIDSA, Associate Professor and Division Chief
Medical School / Graduation date Georgetown University 1972
Internship/residency and year St. Mary's Hospital 1974
Subspecialty training and year Tulane University School of Public Health& Tropical Medicine (MPH&TM) 1975
Louisiana State University School of Medicine (Infectious Diseases) 1977
Northwestern Memorial Hospital (Clinical Microbiology) 1981

Alexander Vandevelde, M.D., Associate Professor
Medical School / Graduation date University of Louvain Medical School, Belgium (MD) 1963
Internship/residency and year St. Vincent's Medical Center 1964
University Medical Center 1969
Subspecialty training and year University of Florida (Infectious Diseases) 1971

Nilmarie Guzman, MD, Assistant Professor
Medical School / Graduation date Ponce School of Medicine, Ponce, PR 1996
Internship/residency and year Damas Hospital, Ponce, PR 1999
Subspecialty training and year University of Florida, Jacksonville (Infectious Diseases) 2006

Levonne Mitchell-Samon, MD, Assistant Professor
Medical School / Graduation date University of South Florida College of Medicine 1997
Internship/residency and year University of Florida, Jacksonville 2000
Subspecialty training and year University of Florida, Jacksonville (Infectious Diseases) 2002

Jeffrey Lauer, MD, Assistant Professor
Medical School / Graduation date University of New Mexico School of Medicine 1994
Internship/residency and year University Medical Center, Jacksonville 1997
Subspecialty training and year University Medical Center, Jacksonville (Infectious Diseases) 1999

Christina Bailey, MD, Assistant Professor
Medical School / Graduation date University of Texas Health Science Center 1995
Internship/residency and year University of Florida, Jacksonville 1998
Subspecialty training and year University of Florida, Jacksonville (Infectious Diseases) 2000

PUBLICATIONS

Kay R. Vandevelde A. Fiorella P. Crouse R. Blackmore C. Sanderson R. Bailey C and Sands M. An outbreak of healthcare associated
multidrug resistant Salmonella Seftenberg in Florida. Inf Control Hosp Epi 2007:28:805-11

Guzman N, Sands M. The aging face of HIV. Northeast Florida Medicine 2007:58:35-36

Guzman N. Sands M. The expanding spectrum of Human T-cell lymphotrophic virus 1 associated neurological disease. Infect Dis Clin Pract
2007:15:236-238

Sands M. McCarter Y. Sanchez W. Synergy testing of multidrug resistant Acinetobacter baumanii against tigecycline and polymyxin using an E-
test methodology. Eur J Clin Microbioal Infect Dis 2007:26:521-2

The strategies for management of antiretroviral therapy (SMART) study group, including Sands M. Major clinical outcomes in antiretroviral
therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study. JID 2008:197:1133-44

The strategies for management of antiretroviral therapy (SMART) study group, including Sands M. Inferior clinical outcomes of the CD4 cell
count-guided antiretroviral treatment interruption strategy in the SMART study: Role of CD4 cell counts and HIV RNA levels during follow-up.
JID 2008:197:1145-55

Vindas-Cordero J, Sands M, Sanchez W. Austrian's triad complicated by suppurative pericarditis and cardiac tamponade: A case report and
review of the literature. IJID 2008

Bailey C. Smith V. Sands M. Hepatitis B vaccine: A seven year study of adherence to the immunization guidelines and efficacy in HIV-1
positive adults. IJID 2008


Annual Report AY 2008


Infectious Diseases


Infectious Diseases






Division Chief: Michael Sands, MD


Irene Alexandraki. MD. Udavan Bhatt. MD. Darcv Plott. MD. Christina Bailey. MD. N. Stanley Nahman. MD. Blood culture isolates in
hemodialysis catheter-related bacteremia. American Journal of Medical Science 2007


Michael Sands., M.D.


HONORS AND AWARDS

Exemplary Teacher

CLINICAL ACTIVITIES


Inpatient activity AY 07/08
Consults 700

Outpatient activity
UF Travel Medicine 850
DCHD HIV/AIDS patients Over 2000
STD visits 4,400
Refugee visits 716
TB visits Over 650


* Encompassing the 10 month period from July 2007 May 2008 only.

GRANTS AND CONTRACTS


Principal Investigator Sponsor/Title

Sands AI424128: A Phase IV, Multi-center, Cross-sectional study to evaluate the 1501. Substitution Among Subjects
Experiencing Virologic Failure on HAART Regimen Containing Atazanavir

Sands NCI-NIH/ Identification and functional analysis of metastasis proteins NV 17751: Observational Cohort Study of
Pneumonia in Fuzeon-Exposed and Non-Exposed Patients.

Sands CPCRA 065: A Large, Simple Trial Comparing Two Strategies for Management of Anti-Retroviral therapy (The SMART
study).

Sands Ceftibuten Study: Evaluation of Single-Dose Ceftibuten for Treatment of Uncomplicated Gonocaccal Urethritis in Men.

Bailey A prospective study of the effect of Compath use on renal transplant outcomes.

Mitchell-Samon An accelerated schedule for Hepatitis B vaccination of HIV patients Pilot study assessing completion rates and
seroconversion

Mannepalli Sleep disorders in elderly HIV infected Afro-American patients seen in a large inner city clinic.

Vindas The prevalence of Candida dublinensis as a cause of thrush in HIV/AIDS patients attending a large inner city clinic

Bailey Antimicrobial susceptibility of GC isolates to an alternative panel of antimicrobial agents.


Annual Report AY 2008


2008


Infectious Diseases


Infectious Diseases





Division Chief: N. Stanley Nahman, Jr, MD


DIVISION OF NEPHROLOGY AND HYPERTENSION
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Nephrology and Hypertension had a prosperous year in all facets of the academic mission. In patient care, the
new Acute Hemodialysis Unit at Shands Jacksonville opened, and our first off site chronic dialysis venture with our dialysis
provider (DCI) opened. In education, the Nephrology Fellowship had a successful first year, with one of our fellows winning 3rd
place at the annual fellows' research competition sponsored by the Southern Society of Clinical Investigation. In addition, we
conducted our first annual "Update in Nephrology" CME course with an excellent response from the physician public. In
research, the division has recruited a new faculty member who is a world expert in glucose transporter proteins (Dr. Charles
Heilig), submitted an NIH grant in collaboration with the US Navy, and continued the collaborative data mining study of the
USRDS with the University of North Florida. Academically, Dr. Maddirala was selected by the Southern Society of the AFMR as
the Young Faculty Investigator of the Year and the division presented abstracts at the ASN, the AFMR and the National Dialysis
Conference.

Patient care: The most important advances this year were the opening of new inpatient and outpatient dialysis units and a
vigorous vascular access program. In October 2007, the new Acute Hemodialysis Unit at Shands Jacksonville was opened. The
unit has 8 open hemodialysis stations, 1 isolation bed, full ICU monitoring, and a digital urinalysis station for performing and
recording all urinalyses. The unit serves as the primary educational platform for nephrology fellows and allows for appropriate
delivery of inpatient dialysis therapies. In the outpatient arena, the new Gateway outpatient dialysis unit opened in June 2008.
The division of Nephrology will serve as the medical directors of the 24 station facility. The rapid growth of our outpatient
dialysis population necessitated this expansion. Finally, with support from DCI, Dr. Bruce Sommer and the division have
established a weekly outpatient vascular access clinic and a busy surgical service for the provision of vascular access in our
dialysis patients.

Education: The most significant event this year was the launching of the Nephrology Fellowship Program in July 2007. The
educational platform provides fellows with high quality training in all facets of inpatient and outpatient Nephrology. Dr. Nahman
helped establish the program, but Dr. Heilig will assume the role of Program Director in 2008. Dr. Maddirala will continue in her
capacity as the Associate PD. All fellows attended the National Kidney Foundation spring meetings in 2008, and Dr. Sullivan
presented his research from the Southern Society competition at those sessions. In February, the division conducted its first
annual Update in Nephrology CME Conference. Speakers included Nephrology faculty and Dr. Bruce Biagi, a physiologist from
Ohio State University. The program was widely applauded by the over 50 participants and we anticipate another session in
2009.

Research: The major accomplishment this year was the establishment of a stable and productive clinical research group that
utilized the USRDS federal dataset. That work has generated several abstracts presented at regional and national meetings.
Drs. Sherif Elfayoume and Peter Wludyka from the University of North Florida continue to be our research collaborators on that
work. Dr.'s Urquidi and Nahman also submitted an NIH grant assessing the effect of circadian rhythm disturbances on
development of metabolic syndrome. The work is a collaborative venture between the division and the US Navy and will study
nuclear submariners. An extension of that project is also being prepared for a Department of Defense grant application later in
2008. In other areas, Dr. Maddirala has established the only HIV nephropathy clinic in Northeast Florida in collaboration with
the Division of Infectious Diseases and the Duval County Health Department. Patients from this clinic will be recruited for future
studies in HIV nephropathy. Dr. Maddirala was also selected by the Southern Society of the AFMR as the Young Faculty
Investigator of the year and presented her work on HIV from the USRDS at the regional meeting in New Orleans. She was also
elected to a 2 year term as counselor of the organization.

In the past year, the division successfully recruited Dr. Charles Heilig (University of Chicago). He is expected to join the group
in summer 2008. Drs. Cuhaci and Vu departed and Dr. Ross cancelled her relocation plans at the last minute. At this time,
recruitment for two more faculty members continues. We anticipate that the substantial progress made in all facets of the
academic mission will help keep the division on a positive trajectory for the coming year and expect the above in-progress
activities to attain fruition during that time.

LISTING OF FACULTY MEMBERS

Gil Cu, MD, Assistant Professor
Medical School / Graduation date University of the Philippines 1983
Internship/residency and year Lutheran Medical Center 1991
Subspecialty training and year Beth Israel Medical Center 1995
Post-doctoral training Rockefeller University 1996

Supriya Maddirala, MD, Assistant Professor
Medical School / Graduation date American University of the Caribbean 2000


Annual Report AY 2008


Nephrology and Hypertension


Nephrology






Division Chief: N. Stanley Nahman, Jr, MD


Internship/residency and year University of Oklahoma 2003
Subspecialty training and year University of Oklahoma 2006

Ronald Mars, MD, Associate Professor
Medical School / Graduation date St Louis University 1972
Internship/residency and year Emory University 1976
Subspecialty training and year Emory University 1978

N. Stanley Nahman, Jr, MD, Professor and Division Chief
Medical School / Graduation date Medical College of Ohio 1979
Internship/residency and year Presbyterian Hospital Denver, Mt Carmel Health, Columbus 1984
Subspecialty training and year The Ohio State University 1987

Virginia Urquidi, PhD, Research Associate Professor
Graduate School and year University of Bilbao, Spain 1978
PhD Oxford University, UK 1992
Post-doctoral training Oxford University, UK 1994



PUBLICATIONS

Urquidi V and Goodison S. Genomic Signatures of Breast Cancer Metastasis. Cytogenetic and Genome Research. 118:116-129, 2007.

Kreunin P, Yoo C, Urquidi V, Lubman DM, Goodison S. Proteomic Profiling Identifies Breast Tumor Metastasis- Associated Factors in an Isogenic
Model Proteomics. 7:299-312, 2007.

Kreunin P, Yoo C, Urquidi V, Lubman DM, Goodison S. Differential expression of ribosomal proteins in a human metastasis model identified by
coupling 2-D liquid chromatography and mass spectometry. Cancer Genomics Proteomics, 4:329-339, 2007.

Maddirala S, Pitha JV, Cowley BC, Haragsim L. End stage renal disease due to polyoma virus in a cardiac transplant patient. Nature Clin Prac
Nephrol, 3:393-396, 2007.

Dickey CA, Kamal A, Lundgren K, Klosak N, Bailey RM, Dunmore J, Ash P, Shoraka S, Zlatkovic J, Echman CB, Patterson C, Dickson D, Hutton M,
Burrows F, Nahman Jr NS, Petrucelli L. The high-affinity Hsp90-CHIP complex recognizes and selectively degrades phosphorylated tau client
proteins. JClin Invest, 117: 648-658, 2007.

Sullivan R, Samuel V, Le C, Khan M, Alexandraki I, Cuhaci B, Nahman Jr NS: Hemodialysis catheter-related bacteremia. Amer J Med Sci,
334:458-465, 2007.

Gupta R, Munoz JC, Garg P, Masri G, Nahman Jr NS, Lambiase, LR: Mediastinal pancreatic pseudocyst a case report and review of the literature.
MedGenMed, 9: 8-15, 2007.

Kreunin P, Zhao J, Rosser C, Urquidi V, Lubman DM, Goodison S. Bladder cancer associated glycoprotein signatures revealed by urinary
proteomic profiling. JProteome Res. 6:2631-2639, 2007

Alexandraki I, Sullivan R, Zaiden R, Bailey C, McCarter Y, Khan A, Offutt, JK, Bhatt U, Plott D, Nahman Jr NS: Blood culture isolates in
hemodialysis vascular catheter-related bacteremia. AmerJMed Sc, in press.

Maddirala S, Hand B, Vincent A, Lau K. Effect Of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on serum potassium
levels and renal function in ambulatory outpatients: risk factor analysis. AmerJ Med Sci, in press.



HONORS AND AWARDS

S Maddirala Young Faculty Researcher of the Year-American Federation for Medical Research, Southern section 2008

S Maddirala Counselor, Southern AFMR 2008

NS Nahman, Jr President, First Coast Nephrology Society 2007

R Sullivan 3rd place Fellows' Research competition American Society for Clinical Investigation, Southern section 2008


Annual Report AY 2008


Nephrology and Hypertension


Nephrology






Division Chief: N. Stanley Nahman, Jr, MD


CLINICAL ACTIVITIES


Inpatient activity AY 07/08
Inpatient Nephrology admissions 388
IP Consults 912
Acute dialysis runs 4445

Outpatient activity
UF Jax Nephrology clinic visits 3078
Outpatient dialysis visits 4500


GRANTS AND CONTRACTS


Annual Report AY 2008


Principal Investigator Sponsor/Title Project period Total direct costs

Urquidi V NCI-NIH/ Identification and functional analysis of metastasis proteins 9/04-8/09 $1,250,000

Urquidi V NCI-NIH/Towards a non-invasive molecular test for bladder cancer 9/07 8/12 $1,450,000

Urquidi V Susan G Komen breast cancer Research Fdn/Isolation of monclonal 7/06 6/09 $200,000
metastasis-inhibiting antibodies

Urquidi V University of Florida Dean's Fund Faculty Research Grant/ The role of MMP8 8/07 9/10 $30,000
protein isoforms in migration and invasion capabilities of breast cancer cells

Sommer B, Nahman Jr Fistula first program/Dialysis Clinic Inc 3/07 2/10 $225,000
NS (Co-PI)

Zaiden R, University of Florida Dean's Fund Resident Research Grant/ Effect of hepatitis 3/06 2/07 $5,000
Nahman Jr NS (mentor) C infection on cellular immunity in hemodialysis patients

Lopez V, University of Florida Dean's Fund Resident Research Grant/ Changes in 8/06 7/07 $2,000
Nahman Jr NS (mentor) hemodialysis blood circuit parameters as predictors of catheter loss in dialysis
patients

Reddy S, University of Florida Dean's Fund Resident Research Grant/ Effect of hepatitis 8/06 7/07 $5,000
Nahman Jr NS (mentor) C viral load on bacteremic events in hemodialysis patients

Darlington A, University of Florida Dean's Fund for Residents and Fellows Research 2/07 -1/08 $5,000
Nahman Jr NS (mentor) Grant/The use of thromboelastography as a tool to predict tunneled catheter
loss

Nguyen T, University of Florida Dean's Fund for Residents and Fellows Research 11/07 10/08 $5,000
Nahman Jr NS (mentor) Grant/Steps Toward Prevention: A Retrospective Analysis of Risk Factors in
ESRD Patients Who Are Exposed to Gadolinum and the Associated
_Development of Nephrogenic Systemic Fibrosis "


Nephrology and Hypertension


Nephrology





Pulmonary, Critical Care & Sleep Medicine


DIVISION OF PULMONARY, CRITICAL CARE & SLEEP MEDICINE
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

The Division of Pulmonary, Critical Care and Sleep Medicine has had a very successful year. We have begun a fellowship
program. Each member of the division has had at least one article accepted or published in a peer-reviewed journal. We have
begun a Pulmonary Hypertension and Interstitial Lung Disease Clinic.

Patient care: The Pulmonary Hypertension and Interstitial Lung Disease Clinic, the Asthma Clinic, the Sleep Clinic, and the
Thoracic Oncology Clinic are all up and running and expanding. We continue to provide Endobronchial Ultrasound and
ultrasound guided placement of pigtail pleural drainage catheters as well as our usual procedures.

Education: The most significant educational event was the submission of the program information form to the ACGME. In
anticipation of accreditation, the Pulmonary and Critical Care Fellowship began 7/1/08. We are currently recruiting a faculty
candidate to become the Fellowship Program Director and a faculty candidate board certified or board eligible in Pulmonary,
Critical Care and Sleep.

Research: The Pulmonary Hypertension and Interstitial Lung Disease Clinic under the directorship of Dr. Bajwa has generated
a fertile ground for research. Research grant applications for these areas will be forthcoming. Again, each member of the
division has independently had at least one article accepted by a peer-reviewed journal this past year.


LISTING OF FACULTY MEMBERS

Abubakr Bajwa, M.D., Assistant Professor
Medical School / Graduation date King Edward Medical College 1999
Internship/residency and year University of South Dakota 2003
Subspecialty training and year Mayo Graduate School of Medicine 2007


James D. Cury, M.D., Associate Professor and Division Chief
Medical School / Graduation date University of Miami 1981
Internship/residency and year Barnes Hospital/Washington 1984
Subspecialty training and year Washington University 1987


Kathryn Koch, M.D, Associate Professor
Medical School / Graduation date John Hopkins 1975
Internship/residency and year Medical University of South Carolina 1977
Subspecialty training and year Case Western 1979

Luis Laos, M.D., Associate Professor
Medical School / Graduation date University Peruana Cayetano Heredia Medical School of Peru 1986
Internship/residency and year SUNY, Brooklyn 1995
Subspecialty training and year University of Florida, Gainesville 1998


PUBLICATIONS

Daniels J, Cury J, Diaz J. An Unusual Cause of Post-Obstructive Pneumonia. Chest. 2007; 13:930-3.

Anatoliotakis N, Chisholm S, Moncur L, Ketty A, Cury J. Tuberculous Bronch-Esophageal Fistula Complicated by Bacterial Midiastinitis. Mauscript
in Press, Chest 2008.

Afessa B, Bajwa AA, Salman SS, Paroxysmal atrial fibrillation in critically ill patients with sepsis. Journal of Intensive Care Medicine (Accepted,
pending publication).

Griffin JP, Koch KA, Nelson JE, Cooley ME. Palliative care consultation, quality-of-life measurements, and bereavement for end-of-life care in
patients with lung cancer. ACCP evidence-based clinical practice guidelines (2nd edition). Chest 2007;132(3 Suppl);404S-422s.

Koch KA. Allow Natural Death: Do Not Resuscitate Orders. Northeast Florida Medicine. 2007 (Suppl);9-13.

Mazidi P, Bajestani S, Khan M, Khair T, Laos L. Goodpasture's Syndrome: A Case Report and Review of Literature. The Internet Journal of
Internal Medicine. 2008:Volume 7, Number 2.


Pulmonary, Critical Care & Sleep Medicine


Division Chief: James D. Cury, M.D.


Annual Report AY 2008





Pulmonary, Critical Care & Sleep Medicine


Laos L. Cardiac Papillary Fibroelastoma: Case report and review of the literature. International Journal of Cardiology. Accepted for Publication
HONORS AND AWARDS


James D. Cury, M.D.


University of Florida Exemplary Teacher


CLINICAL ACTIVITIES


Inpatient activity AY 07/08
Inpatient Pulmonary Admissions 507
Inpatient Days 4264
Average Length of Stay 8.41
Number of IP Consults 1016

Outpatient activity
Clinical Visits 3268

Procedures
Bronchoscopies 530
Sleep Studies 497


Pulmonary, Critical Care & Sleep Medicine


2008


Division Chief: James D. Cury, M.D.


Annual Report AY 2008





Division of Rheumatology and Clinical Immunology


DIVISION OF RHEUMATOLOGY AND CLINICAL IMMUNOLOGY
ACADEMIC YEAR 2008 (7/07 6/08)

Highlights

There has been a steady growth in patient care, research and education. Dr. Mitri joined UF Jacksonville as the Division Chief
in September 2007 as the first full-time rheumatologist in over ten years. There is a major shortage of rheumatologists in
Jacksonville. After significant efforts in that academic year, two full-time physicians were recruited and will join the division in
February 2009 and July 2009. We achieved full-time coverage of out-patient and in-patient consults and services. In
collaboration with the GI division we are providing an expanding IV infusion services in the out-patient setting. Education was
emphasized with more student and resident rotations, lectures, guest speakers, and round table discussions covering multiple
rheumatological and healthcare related issues. Academically, the division submitted an abstract to the ACR meeting in San
Francisco in October 2008 and has been working separately and in collaboration with other divisions on numerous clinical trials.

Patient care: The most important achievement was improving access to rheumatological services in the out-patient and in-
patient settings. In previous years, the next available appointment for a new patient exceeded 6 months, but it has been
minimized to several weeks. In-patient rheumatology consultations are now covered by a board certified rheumatologist 24/7
throughout the year. More specialized and patient oriented services are constantly being added to the out-patient setting, such
as various infusion services and musculoskeletal ultrasound in the near future. The goal is to provide the highest quality of care
in response to our patient's needs and take leadership position in patient satisfaction and among other institutions.

Education: Education is one of the division's top priorities. It is the key element in advancing healthcare and recruiting the
rheumatologists of the future. Numerous medical students and residents rotated in the out-patient and in-patient consultative
services. Dr. Mitri volunteered in the Internal Medicine Residency Program rounds as an attending. Numerous lectures were
given to the internal medicine residents and other training programs within UF Jacksonville, grand rounds including invited
guest speakers. Numerous round table discussion involving residents, faculty from UF and Mayo Clinic in Jacksonville were
facilitated in order to strengthen the collegial and collaborative efforts between our educational institutions, residents, and
faculty members.

Research: Dr. Mitri submitted an abstract to the American College of Rheumatology Annual Meeting in October 2008 titled:
"High Levels of Serologic and Inflammatory Markers in Rheumatoid Arthritis are Associated with Poor Functional Status", which
evaluated the relationship between currently available diagnostic tests and assessment tools and a new functional status
numerical scale commonly used in our practice.

We are also working in conjunction with the Division of Gastroenterology on a investigator initiated study regarding arthritis and
pain in patients with chronic hepatitis C.

LISTING OF FACULTY MEMBERS

Archana Goel, M.D., Assistant Professor
Medical School / Graduation date G.S.V.M. Medical College, Kanpur India 1990
Internship/residency and year Albert Einstein College of Medicine, Bronx, NY 1994
Subspecialty training and year New York University 1996

Ghaith Mitri, M.D. M.M.M., Assistant Professor and Division Chief
Medical School / Graduation date Damascus University School of Medicine 1995
Internship/residency and year Scranton Temple University 1999
Subspecialty training and year University of Pittsburg School of Medicine 2001
Post-Graduate Training and year Marshall School of Business, USC 2007


CLINICAL ACTIVITIES


Inpatient activity AY 07/08
Number of IP Consults 58

Outpatient activity
Clinical Visits 2363


Rheumatology/Clinical Immunology


Division Chief: Ghaith Mitri, MD, MMM


Annual Report AY 2008




























Department of Medicine
Annual Faculty Meeting
June 2008










Department of Medicine
University of Florida
College of Medicine Jacksonville
653-1 West 8th Street, L20
Jacksonville FL 32209
904-244-8846
www.hscj.ufl.edu/im/




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