• TABLE OF CONTENTS
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 Front Cover
 Table of Contents
 Statement from the Chairman
 Departmental organizational...
 Continuing medical education
 Graduate medical education
 Individual divisions
 Community involvement
 Notes
 Back Cover






Title: Department of Medicine annual report
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Title: Department of Medicine annual report academic year 2006 - 2007
Series Title: Department of Medicine annual report
Physical Description: Serial
Language: English
Creator: College of Medicine, University of Florida
Publisher: College of Medicine, University of Florida
Place of Publication: Jacksonville, Fla.
Publication Date: 2006-2007
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Bibliographic ID: UF00090036
Volume ID: VID00001
Source Institution: University of Florida
Holding Location: University of Florida
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Table of Contents
    Front Cover
        Front Cover
    Table of Contents
        Page 1
        Page 2
    Statement from the Chairman
        Page 3
        Page 4
    Departmental organizational overview
        Page 5
        Page 6
        Page 7
        Page 8
    Continuing medical education
        Page 9
        Page 10
    Graduate medical education
        Page 11
        Page 12
        Page 13
        Page 14
        Page 15
        Page 16
    Individual divisions
        Page 17
        Page 18
        Page 19
        Page 20
        Page 21
        Page 22
        Page 23
        Page 24
        Page 25
        Page 26
        Page 27
        Page 28
        Page 29
        Page 30
        Page 31
        Page 32
        Page 33
        Page 34
        Page 35
        Page 36
        Page 37
        Page 38
        Page 39
        Page 40
        Page 41
        Page 42
        Page 43
        Page 44
        Page 45
        Page 46
        Page 47
        Page 48
        Page 49
        Page 50
        Page 51
        Page 52
        Page 53
        Page 54
        Page 55
        Page 56
        Page 57
        Page 58
        Page 59
        Page 60
    Community involvement
        Page 61
        Page 62
    Notes
        Page 63
        Page 64
    Back Cover
        Back Cover
Full Text





Department of Medicine


Annual Report

Academic Year 2006 2007




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UF


UNIVERSITY of
FLORIDA
College of Medicine
Jacksonville






Department of Medicine


TABLE OF CONTENTS
ACADEMIC YEAR 2007 (7/06 6/07)


I. Statement from the Chairman

II. Department Organizational Overview
a. Administration
b. Division Chiefs
c. Residents/Fellows

III. Continuing Medical Education
a. Medical Grand Rounds and Noon Conferences
b. Conferences and Symposiums

IV. Graduate Medical Education
a. Internal Medicine Residency Training Program
b. Subspecialty Fellowship Program
c. Student Education Programs

V. Individual Divisions
a. Cardiology
b. Endocrinology
c. Gastroenterology
d. General Internal Medicine
e. Hematology/Oncology
f. Hospital Medicine
g. Infectious Disease
h. Nephrology and Hypertension
i. Pulmonary and Critical Care

VI. Community Involvement










Department of Medicine
University of Florida
College of Medicine Jacksonville
653-1 West 8th Street
Jacksonville FL 32209
904-244-8846
www.hscj.ufl.edu/im/


Department of Medicine


Table of Contents


Annual Report AY 2007





























































































2







Department Chair: Arshaa Mooradian, MD


STATEMENT FROM THE CHAIRMAN
ACADEMIC YEAR 2007 (7/06 6/07)

Dear Colleagues and Friends:

As an important teaching site for the University of Florida College of Medicine the Department of
Medicine in Jacksonville pursues the three traditional missions of academic institutions; patient care,
teaching and research. I will briefly describe the scope of accomplishments for the 2006-2007 academic
year:

Patient care: The Department expanded clinical activities and achieved 102% of budgeted charges.
The Division of Hospital Medicine expanded three fold to keep in pace with increasing demands of
hospital admissions. Successful recruitments were achieved in all Divisions within the Department.
Several service contracts were negotiated with the Veterans' Administration, Department of Health, and
other private health care providers in Jacksonville. Clinical operations were reorganized to reduce cost
and increase the number of patient visits.

Education: Faculty members of the Department continue to excel in their mission of educating students
and residents. The Department has been the winner of the Golden Apple Award for the best clinical
clerkship for the last three consecutive years. Internal Medicine has been the highest rated experience
overall on the Graduation Questionnaire for the last three consecutive years and rated higher than the
national average. A dedicated cadre of teaching faculty on both campuses invests significant time
mentoring students and providing feedback. The post graduate education program is thriving in the core
and subspecialty programs. The Department continues to sponsor multiple continuing medical education
venues.

Research: The Department had an exceptionally productive year in research. There were a total of 77
peer reviewed publications and 15 book chapters authored by faculty members. Faculty made 52
national and regional presentations. During fiscal year 2007, 37 research awards with a direct cost of
$903,597 were acquired. This represents a 321.6% change compared to the previous fiscal year.

Since joining the Department a year ago, I continue to be impressed by the high quality and
achievements of faculty and staff. I hope this annual report will serve as an insider look into the
Department of Medicine and highlight our continuing commitment to excellence in patient care,
teaching, and research.

Sincerely,

Arshag D. Mooradian, M.D.
Professor and Chairman


Statement from the Chairman


Statement from the Chairman


Annual Report AY 2007





























































































4







Organizational Overview DeDartment of Medicine


DEPARTMENT ORGANIZATIONAL OVERVIEW
ACADEMIC YEAR 2007 (7/06 6/07)


Arshag D. Mooradian, M.D.
Chairman, Department of Medicine

N. Stanley Nahman, M.D.
Program Director, Internal Medicine Residency

Arpitha Ketty, M.D.
Associate Program Director, Graduate Medical Education

Olga Petrucelli, M.D.
Associate Program Director, Graduate Medical Education

Carlos Palacio, M.D.
Director, Medical Student Clerkship

Irene Alexandraki, M.D.
Associate Director, Medical Student Clerkship

Christina Catalano, M.B.A.
Administrator

Nanci Morton
Administrative Manager


DIVISION CHIEFS


Cardiology

Endocrinology

Gastroenterology

General Internal Medicine

Hematology/Oncology

Hospital Medicine

Infectious Disease

Nephrology and Hypertension

Pulmonary and Critical Care

Rheumatology

Annual Report AY 2007 5


Theodore Bass, M.D.

Robert Lavine, M.D.

Louis Lambiase, M.D.

Linda Edwards, M.D.

James Chingos, M.D.

Jeffrey House, D.O.

Michael Sands, M.D.

N. Stanley Nahman, M.D.

J. Davis Cury, M.D.

Archana Goel, M.D., Interim Chief

Department Organizational Overview


Oroanizational Overview


Department of Medicine







Organizational Overview DeDartment of Medicine


RESIDENTS/FELLOWS


Chief Residents 2006-2007


Bharat K. Gummadi, M.D.
Medical School: St. George's University, 2003

Erik S. Lowman, D.O.
Medical School: Nova Southeastern University, 2003

CLASS OF 2006/2007


MEDICAL SCHOOL


Melvin Bullock, M.D.
Andrew Darlington, D.O.
Friba Faqeeri, M.D.
Somajita Ghosal, M.D.
Henry Heyman, M.D.
Dongmei Jiang, M.D.
Mohammad Asif Khan, M.D.
Malca Kierson, D.O.
Carol Le, M.D.
Nimish Naik, MD.
Thomas Nguyen, M.D.
Chaturani Ranasinghe, M.D.
Vinny Samuel, M.D.
Kalina Sanders, M.D.
Vandana Seeram, M.D.
Timothy Shepherd, M.D.
Chut Sombutmai, D.O.
Siva Suryadevara, M.D.
Justin Upp, M.D.
Esther Vildor-Dazil, M.D.


Medical College of Georgia
Philadelphia College of Osteopathic Medicine
Ross University
Calcutta National Medical College
Medical College of Georgia
Bejing Medical University
Khyber Medical College
Chicago College of Osteopathic Medicine
Medical College of Wisconsin
New York Medical College
Drexel University College of Medicine
University of Miami School of Medicine
Ross University
Univ. of Texas Medical School At San Antonio
University of West Indies
University of Florida College of Medicine
Nova Southeastern University
University of the West Indies Trinidad
University of Florida College of Medicine
Florida State University College of Medicine


HOUSESTAFF II


MEDICAL SCHOOL


1. Rosalyn Alcalde, M.D.
2. Gina Chacon, M.D.
3. Ruchi Gupta, M.D.
4. Michael Hernandez, M.D.
5. Sarah Katta, D.O.
6. Victor Lopez de Mendoza, M.D.
7. Ashwin Mehta, M.D.
8. Latonia Moncur, M.D.
9. Soo Nam, M.D.
10. Timmy Nguyen, M.D.
11. Juan Danny Pulido, M.D.
12. Shilpa Reddy, D.O.


HOUSESTAFF III


Ross University
Universidad Catolica de Santa Maria
Lady Hardinage Medical College
Florida State University College of Medicine
Nova Southeastern University
Universidad Central Del Este
St. George's University
St. George's University
Ross University
Flinders University of South Australia
Universidad de Ciencias Medicas
Nova Southeastern University


MEDICAL SCHOOL


1. Nikolaos Anatoliotakis, M.D.
2. Fabian Arnaldo, M.D.
3. Rodolfo Barroso, M.D.
4. Sian Chisholm, M.D.
5. Khalil Khan, D.O.

Annual Report AY 2007


University of Crete
Universidad de Buenos Aires
American University of the Caribbean
Ross University
Nova Southeastern


HOUSESTAFF I


Department Organizational Overview


Oroanizational Overview


Department of Medicine







Organizational Overview DeDartment of Medicine


6. Frederick Martinez, M.D.
7. Neeta Panse, M.D.
8. Darceilia Plott, M.D.
9. Haritha Sakhamuri, M.D.
10. Mohammad Shehadeh, M.D.
11. Robert Sullivan, M.D.
12. Robert Zaiden, M.D.


University of Illinois College of Medicine
Grant Medical College
Ohio State University
PSG Institute of Medical Sciences
Universidad Central Del Caribe
Ross University
St. Matthews University School of Medicine


SUBSPECIALTY FELLOWSHIP PROGRAM DIRECTORS


Cardiology: Steven Lavine, M.D.
Gastroenterology: Louis Lambiase, M.D.
Interventional Cardiology: Ted Bass, M.D.
Infectious Diseases: Michael Sands, M.D.
Medical Oncology: James Chingos, M.D.


SUBSPECIALTY FELLOW HOUSESTAFF IV

Nikesh Jasani, M.D. (Oncology)
Peyman Salimi-Tari, M.D. (Oncology)
Matthew Cole, M.D. (Gastroenterology)
Sunitha Pudhota, M.D. (Gastroenterology)
Jose Vindas-Cordero, M.D. (Infectious Disease) Jan 07
M. Kamran Aslam, M.D. (Cardiology)
Lori McMullan, M.D. (Cardiology)
A. Tony Ortiz, M.D. (Cardiology)
Derek Sun, M.D. (Cardiology)

SUBSPECIALTY FELLOW HOUSESTAFF V

Shalin Shah, D.O. (Oncology)
Mary Alizadeh, M.D. (Gastroenterology)
Ghassan Hammoud, M.D. (Gastroenterology)
Wilfredo Sanchez, M.D. (Infectious Disease)
Amitra Caines, M.D. (Cardiology)
Juan Estrada, M.D. (Cardiology)
Binu Jacob, M.D. (Cardiology)
Dao Pham, M.D. (Cardiology)
10. Ian Weisberg, M.D. (Cardiology)

SUBSPECIALTY FELLOW HOUSESTAFF VI

Linda Di Teodoro, M.D. (Gastroenterology)
Samir Habashi, M.D. (Gastroenterology)
Lyndon Box, M.D. (Cardiology)
Erik Carlson, M.D. (Cardiology)
Chris Pavlovic, M.D. (Cardiology)
Prithviraj Rai, M.D. (Cardiology)
Steven Shoemaker, M.D. (Cardiology)

SUBSPECIALTY FELLOW HOUSESTAFF VII


MEDICAL SCHOOL


St. Georges University
University of Sydney
Ross University
Osmania Medical College
Universided de Costa Rica, San Jose
University of Texas
Louisiana State University
University of Miami
Drexel University

MEDICAL SCHOOL

Nova Southeastern University
University of Colorado School of Medicine
University of New Mexico
Ponce School of Medicine
Case Western Reserve University
Universidad Nacional Autonoma de Honduras
University of Miami
University of Alabama
Emory University

MEDICAL SCHOOL

St. George's University
Ain Shams University
University of Alabama-Birmingham
Medical College of Georgia
Washington University School of Medicine
Kasturba Medical College
University of Florida

MEDICAL SCHOOL


Nova Southeastern University
University of Oklahoma


Department Organizational Overview


Vafa Mansouri, D.O. (Interventional Cardiology)
Robert Smith, M.D. (Interventional Cardiology)


Oroanizational Overview


Department of Medicine


Annual Report AY 2007





























































































8








CONTINUING MEDICAL EDUCATION
ACADEMIC YEAR 2007 (7/06 6/07)


The mission of the University of Florida Continuing Medical Education program is to provide lifelong
learning experiences for physicians that support their intentional efforts to enhance competence in
patient care, medical knowledge, practice-based learning and improvement, interpersonal and
communication skills, professionalism and systems-based practice. This mission is accomplished through
the provision and support of seminars, workshops, review courses, symposia, conferences, meetings,
lecture series, enduring materials, distance education modules, grand rounds, mini-fellowships and
visiting professors programs focused on these competencies.


MEDICAL GRAND ROUNDS & NOON CONFERENCES

The goal of Medical Grand Rounds and Noon Conferences is to provide didactic sessions on each clinical
condition that may not be sufficiently addressed during other educational experiences within the Internal
Medicine Residency Program. Didactic sessions are presented as part of an 18-month curriculum to
ensure each resident has an opportunity to complete the curriculum over the course of his or her 3-year
residency. To accomplish this goal, the Program Director, in conjunction with the Subspecialty Education
Coordinators or other responsible faculty, reviews the educational experiences provided within the
residency program and select topics to be addressed.

Conferences include information from basic medical sciences, with emphasis on pathophysiology of
disease and recent advances in clinical medicine and biomedical research. Medical Grand Rounds are
held weekly and Noon Conferences are held daily. Quarterly, Clinical Pathology Conferences correlate
current pathology material, including material from autopsies, surgical specimens, and other pathology
with clinical course and management of patients. Monthly clinical quality improvement (morbidity and
mortality) conferences focus on adverse clinical events on teaching services. Monthly resident
presentation of Scholarly Activity consist of PGY2 & PGY3 residents who are assigned to present topic
reviews once each 12 months.

Residents are encouraged to take advantage of the maximum number of conferences possible to
optimize their fund of clinical knowledge and are required to attend 60% of the Core Conferences
offered. Residents at every level of training are required to attend Morning Report when rotating on
Inpatient Internal Medicine, Neurology, On-site Ambulatory Care and sub-specialty consult services. All
residents on campus are encouraged to attend the Autopsy Conference, which is held weekly in the
Morgue. Weekly scheduled didactics occur formally on the Inpatient Medicine, Cardiology, and MICA
Rotations. Didactic Teaching occurs informally on all subspecialty rotations.


CONFERENCES & SYMPOSIUMS

The Department of Medicine had two main conferences this academic year; Internal Medicine Update
2007 and Topics in Cardiology.

This year's Internal Medicine Update included topics on proton beam therapy with an emphasis on lung
cancer therapy, pain management, endocrinology, cardiology, nephrology, dermatology, medical literacy,
several interesting case presentations and a luncheon speaker from NASA. Presentations and lectures


Annual Report AY 2007 Continuing Medical Education


Continuing Medical Education


Department of Medicine








highlighted topics such as advances in insulin therapy, metabolic syndrome, aerospace medicine,
cutaneous neoplasms and integrative approaches to chronic pain.

Upon completion of the Internal Medicine Update, participants should have been able to describe the
latest advancements in research related to sub-specialties discussed, identify current diagnosis and
treatment options for conditions described above that are presented to family medicine physicians and
internists, and state the importance of preventative actions that practitioners may encourage patients to
employ, particularly to promote changes in patient behavior.

The Division of Cardiology hosted Topics in Cardiology, which was designed to present important and
practical new information, particularly for primary care clinicians and allied health care professionals who
are interested in improving the health outcomes for patients with cardiovascular disease. This
continuing education activity highlighted the practical aspects of recent scientific recommendations and
guidelines on several topics, including: coronary artery disease, including recent trials in interventional
cardiology, acute coronary syndromes, risk factor modification, approaches to congestive heart failure,
and advances in MR & CT as well as peripheral vascular disease.

The course objectives for Topics in Cardiology were to increase awareness of therapies and diagnoses of
peripheral vascular disease, enhance the understanding of comprehensive management of coronary risk
factors, review new diagnostic techniques and therapies in patients with congestive heart failure, and
explore current issues involving atherosclerosis, supraventricular arrhythmias, MR/CT, and angiogenesis.


Continuing Medical Education


Continuing Medical Education


Department of Medicine


Annual Report AY 2007








GRADUATE MEDICAL EDUCATION
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Office of Graduate Medical Education (GME) had another successful year of program maturation and
leadership development. The year was highlighted by another successful Match, establishment of a new
Nephrology Fellowship Program, and rapid growth of faculty numbers in the Department of Medicine.
Teaching and leadership skills of program leaders and key clinical faculty were raised through
participation in the Master Educator Program and research productivity by trainees and faculty continued
to expand.

Internal Medicine Residency Program. Dr. Nahman continued in his capacity as Program Director (PD)
and Drs. Arpitha Ketty and Olga Petrucelli remained Associate Program Directors. Our 4th year Chief
Administrative Residents were Drs. Bharat Gummadi and Eric Lowman. Curricular advancements
included continued utilization of mega-teams on ward rotations, refinement of the Friday afternoon
Board Review Course and re-organizing night float rotation from a single month into two, 2 week blocks.
The graduating class of 2007 sent 6 residents to chief residency positions or fellowships, with the
remaining pursuing Hospitalist Medicine or private practice options.

The intern Match class for 2007 boasted a mean step 1 USMLE score of 210, exhibiting the strongest
step 1 test scores of the last 4 recruitment years. This class was carefully chosen for strong academic
qualities in conjunction with the plan to strengthen resident performance on the ABIM Certification
Examination. In October 2006, 2 fourth year chief medical residents were recruited from the junior class
to serve in 2008-09, and in-training exam scores continued to improve. All program directors attended
at least 1 APDIM or other national education meeting, and incoming chief medical residents (CMR)
attended the APDIM-sponsored CMR orientation in the spring. Drs. Ketty, Petrucelli, and Alexandraki
enrolled in the 18 month Master Educator Program sponsored by the University of Florida and joined
many other key clinical faculty members in the course. In research, residents submitted abstracts to
the Florida ACP, American Society of Nephrology, and Southern Section of the AFMR, and accounted for
12 internal research grants, 10 published manuscripts and 11 published abstracts.

Subspecialty Fellowship Programs. An ACGME application to establish a new Nephrology Fellowship
Training Program was approved in May 2006, and will join 5 other accredited subspecialty fellowship
programs (Cardiology, Interventional Cardiology, Gastroenterology, Medical Oncology, and Infectious
Disease). Dr. Nahman directs the Nephrology Program and will be assisted by Associate PD Dr. Supriya
Maddirala. Dr. Janet Hosenpud was recruited to direct the Medical Oncology Fellowship Program
beginning July 2007. She will be assisted by current interim PD for Medical Oncology, Dr. Fauzia Rana.
Dr. Christina Bailey joined Dr. Michael Sands as an Associate PD for Infectious Disease. The
Gastroenterology Fellowship was revised in accordance with RRC recommendations following the 2005
site visit and is awaiting announcement of the next site visit date.

Student Education Programs. Medical student education programs are directed by Drs. Carlos Palacio
and Irene Alexandraki. Chairman rounds and student morning report continue to be offered and are
well received by students. Both physician leaders attended student clerkship sessions of the National
APDIM Meeting and work closely with Gainesville faculty to keep the highly rated student program an
effective learning tool.




Annual Report AY 2007 Graduate Medical Education


Graduate Medical Education


Proararn Director: N. Stanlev Nahman. Jr MD









LISTING OF PROGRAM LEADERSHIP

New Faculty

Bharat Gummadi, MD, Post-doctoral Associate and Chief Medical Resident

Medical School / Graduation date St. Georges University 2003
Internship/residency and year University of Florida Jacksonville 2006
Chief Medical Resident University of Florida Jacksonville 2007

Eric Lowman, DO, Post-doctoral Associate and Chief Medical Resident

Medical School / Graduation date Nova Southeastern College of Osteopathic Medicine 2003
Internship/residency and year University of Florida Jacksonville 2006
Chief Medical Resident University of Florida Jacksonville 2007

Current Faculty

Irene Alexandraki, MD, Assistant Professor and Associate Student Clerkship Director

Medical School / Graduation date University of Athens Medical School 1989
Internship/residency and year Hahneman University 1998
Subspecialty training and year Infectious disease/Baylor College of Medicine 2001

Arpitha Ketty, MD, Assistant Professor and Associate Program Director

Medical School / Graduation date University of Southern California 1999
Internship/residency and year University of California Davis 2002

N. Stanley Nahman, Jr., MD, Professor and Program Director

Medical School / Graduation date Medical College of Ohio 1979
Internship/residency and year Presbyterian Hospital Denver, Mt Carmel Health, Columbus 1984
Subspecialty training and year Nephrology/The Ohio State University 1987

Carlos Palacio, MD, Assistant Professor and Student Clerkship Director

Medical School / Graduation date University of Miami 1993
Internship/residency and year University of Florida Jacksonville 1996
Chief Medical Resident University of Florida Jacksonville 1997

Olga Petrucelli, MD, Assistant Professor and Associate Program Director

Medical School / Graduation date University of South Florida 1996
Internship/residency and year University of Chicago 1999



PUBLICATIONS

Garg P, Gupta R, Hsi D, Shiels L, DiSalle M. Hypertrophic cardiomyopathy an symptomatic conduction system
disease in cardiac amyloidosis. South MedJ. 2006 Dec; 99(12):1390-2.

Arnaldo F, Pulido M, House J. Cocaine-induced non-STEMI: an unusual electrocardiography presentation.
Emerg MedJ. 2006 Oct; 23(10):816-7.

Chacon G, Alexandraki I, Palacio C. Collet-Sicard syndrome: an uncommon manifestation of metastatic prostate

Annual Report AY 2007 Graduate Medical Education


Graduate Medical Education


Proararn Director: N. Stanlev Nahman. Jr MD






Graduate Medical Education Program Director: N. Stanley Nahman, Jr MD

cancer. South MedJ. 2006; Vol. 99:8 Aug 2006.

Arnaldo F, Anatoliotakis N. Hypothermia-induced J waves. Int J Cardiol. 2007 Jan 18; 114(3):e116-7. Epub 2006
Oct 17.

Rascon I, Pamer M, Vega K, Cury J, Nahman Jr. NS. The role of gastroesophageal reflux in exacerbations of
chronic obstructive pulmonary disease. Chest. 2006 Oct; 130(4):1096-101.

Garg P, Gupta R, Szalados J. Bacterial Pericarditis and tamponade due to nonencapsulated haemophilus
influenzae complicating a case of adult community-acquired pneumonia. Medscape General Medicine. 2006;
8(4):48. 2006

Daniels JT, Cury JD, Diaz J. An unusual cause of post obstructive pneumonia. Chest. 2007 131:930-3

Khan MA, Renganathan R. Varying practices of Warfarin dosing regimen, could we modify this? Irish Medical
Journal. 2007.

Lowman E, Mooradian AD. Macromelia masquerading as an acromegaloid syndrome in an adult with Klippel-
Trenaunay syndrome. Endocrine Practice. (In press) 2007.

Sullivan R, Samuel V, Le C, Khan M, Alexandraki I, Cuhaci B, Nahman Jr. NS: Hemodialysis catheter-related
bacteremia. AmerJMedSci, in press.

Sakhamuri H, Bhatt U. Hemodynamic impact of CRRT in trauma versus non-trauma patients. J Am Soc
Nephrol, 17:107A, 2006.

Sullivan R, Zaiden R, Jones D, Alexandraki I, Bhatt U, Vu H, Nahman, Jr. NS.: Relationship between hepatitis
C and bacteremia in hemodialysis patients with catheters. Presented, Southern AFMR. J Invest Med, 54:S298,
2006.

Sullivan R, Zaiden R, Reddy S, Lopez V, Kim H, Alexandraki I, Nahman, Jr. NS. Surveillance cultures in
hemodialysis patients with vascular catheters. Presented. American Society of Nephrology, JAmer Soc Nephrol,
17: 589A, 2006.

Zaiden R, Sullivan R, Reddy S, Lopez V, Kim H, Alexandraki I, Nahman, Jr. NS.: Cross-sectional study of
the relationship between hepatitis C and bacteremia in hemodialysis patients with vascular catheters. Presented.
American Society of Nephrology, J Amer Soc Nephrol, 17:589A, 2006.

Reddy S, Zaiden R, Sullivan R, Naik N, Alexandraki I, Nahman, Jr. NS.: Hepatitis C viral load and the risk of
bacteremia in hemodialysis patients with vascular catheters. Presented, Southern AFMR. JInvestMed, 55:S308,
2007.

Lopez de Mendoza V, Reddy S, Sullivan R, Le C, Naik N, Zaiden R, Alexandraki I, Nahman, Jr. NS. Natural
history of vascular access catheters in hemodialysis patients. Presented, Southern AFMR. JInvestMed, 55:S272,
2007.

Ketty A, Petrucelli O, Katta S, Nahman, Jr. NS.: Effect of Resident Manpower on Work Rounding Frequency.
Presented, Southern AFMR. J nvestMed, 55:S286, 2007.

Sakhamuri H, Urquidi V, Nahman Jr. NS, Petrucelli OM: Effect of red cells, leukocytes and bacteria on urine
dipstick testing for protein: role in the transient albuminuria of urinary tract infection. Presented, Southern
AFMR. J nvestMed, 55:S272, 2007.

Katta S, Sakhamuri H, Samuel V, Nahman Jr. NS, Ketty A: Age related changes in renal function in sickle cell
disease. American Society of Nephrology, JAmer Soc Nephrol, in press
Annual Report AY 2007 13 Graduate Medical Education











Reddy S, Elfayoumy S, Wludyka P, Britt K, Maddirala S, Cuhaci B, Mars R, Cu G, Vu H, Urquidi V, Lambiase L,
Nahman Jr. NS: Vascular catheters and hepatitis C in the development of bacteremia in ESRD patients: logistic
regression analysis from the DMMS study. Presented. American Society of Nephrology, JAmer Soc Nephrol, in
press

Lopez de Mendoza V, Naik N, Mars R, Cuhaci B, Nahman, Jr. NS: Effect of vascular catheter failure on
dynamic hemodialysis circuit pressures. American Society of Nephrology, JAmer Soc Nephrol, in press



HONORS AND AWARDS


Andy Darlington, DO

Rudy Barroso, MD


Intern of the Year

Resident of the Year


Senthil Meenrajan, MD Teacher of the Year


Carlos Palacio, MD
Manish Relan, MD
Robert Zaiden, MD


Exemplary teachers
University of Florida


ENDOWMENTS AND GIFTS

The Anne and Max Michael, Jr. Education fund Established 2006, by Anne Michael



GRANTS AND CONTRACTS
Up to $5, 000 each


Principal Sponsor/Title
Investigator
Sullivan, Robert University of Florida Dean's Fund Resident Research Grant/ Risk factors for gram negative bacteremia and central venous
dialysis access

Zaiden, Robert University of Florida Dean's Fund Resident Research Grant/ Effect of hepatitis C infection on cellular immunity in
hemodialysis patients

Lopez de Mendoza, University of Florida Dean's Fund for Residents and Fellows Research Grant, "Changes in hemodialysis blood circuit
Victor parameters as predictors of catheter loss in dialysis patients".

Reddy, Shilpa University of Florida Dean's Fund for Residents and Fellows Research Grant: "Effect of hepatitis C viral load on bacteremic
events in hemodialysis patients".

Sakhamuri, Haritha University of Florida Dean's Fund for Residents and Fellows Research Grant: "The incidence of transient proteinuria in
urinary tract infection".

Katta, Sarah University of Florida Dean's Fund for Residents and Fellows Research Grant: "Age-related changes to renal function in
patients with sickle cell disease."

Mehta, Ashwin University of Florida Dean's Fund for Residents and Fellows Research Grant: "Enlighten encouraging dialogue about
decisions to limit life sustaining treatment using educational videos."

Pulido, Danny University of Florida Dean's Fund for Residents and Fellows Research Grant: "The Incidence of Cardiovascular Diseases in
Athletes and Methods of Screening."

Panse, Neeta University of Florida Dean's Fund for Residents and Fellows Research Grant: "Trends in Inflammatory Breast Cancer,
Incidence and Survival at UF Jacksonville."
Annual ..... A .. Mealca- .a ..


2007

2007

2007

2007


Graduate Medical Education


Proararn Director: N. Staniev Nahman. Jr MD


Annual Report AY 2007


Graduate Medical Education












Gupta, Ruchi University of Florida Dean's Fund for Residents and Fellows Research Grant: "Use of Acid Suppression Therapy In
Hospitalized Patients-Going Beyond The Indications."

Darlington, Andrew University of Florida Dean's Fund for Residents and Fellows Research Grant: "The use of thromboelastography as a tool to
predict tunneled catheter loss."

Shepherd, Timothy University of Florida Dean's Fund for Residents and Fellows Research Grant, 2007: "High Resolution MRI of Hippocampal
Sclerosis using the Diffusion Orientation Transform."


Annual Report AY 2007 Graduate Medical Education


Graduate Medical Education


Proararn Director: N. Staniev Nahman. Jr MD


Annual Report AY 2007


Graduate Medical Education







GradateMedcal ductio ProramDirctor N.Staley ahmn. r M


POST-GRADUATE ACTIVITIES OF CMR AND SENIOR RESIDENTS


Graduate


Professional status


Location


Outgoing Chiefs


Bharat Gummadi, MD


Erik Lowman, DO


Heart failure fellow 2007
Fellowship, Cardiology 2008

Fellowship, Infectious disease


University of Florida Jacksonville
University of Florida Jacksonville

Rush University, Chicago


Graduating residents


Nik Anatoliotakis, MD
Sian Chisholm, MD
Fabian Arnaldo, MD
Rodolfo Barroso, MD
Khalil Khan, DO
Fred Martinez, MD
Neeta Panse, MD
Darcy Plott, MD
Haritha Sakhamuri, MD
Mohammad Shehadeh, MD
Robert Sullivan, MD
Robert Zaiden, MD


Chief Medical resident
Chief Medical resident
Fellowship, Cardiology
Private practice
Private practice
Hospitalist
Hospitalist
Private Practice
Fellowship, Nephrology
Private practice
Fellowship, Nephrology
Fellowship, Medical Oncology


University of Florida Jacksonville
University of Florida Jacksonville
Cleveland Clinic, Westin Florida
Miami, Florida
Ft. Lauderdale, Florida
Savannah, Georgia
University of Florida Jacksonville
Columbus, Ohio
University of Florida Jacksonville
San Juan, Puerto Rico
University of Florida Jacksonville
University of Florida Jacksonville


Annual Report AY 2007 Graduate Medical Education


Graduate Medical Education


Proararn Director: N. Stanlev Nahman. Jr MD


Annual Report AY 2007


Graduate Medical Education








DIVISION OF CARDIOLOGY
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Cardiovascular Center/Division of Cardiology had a strong fiscal year in 2006/2007 and a very
productive year in research. The division continued practice in Lake City and St. Mary's, Georgia, both
being strong practices which ramped up in volume over the past year. The new cardiovascular inpatient
unit opened in September 2006. We continued to expand the Peripheral Interventional Program,
aggressively marketing to primary care and internal medicine practices. All activities resulted in increased
volume. The following are goals and objectives for FY 2007:

In collaboration with Radiology, further develop the Cardiac Advanced Imaging Program (CT
and MRI program).
Expand the Electrophysiology Program to satellite offices. Proceed with plans to start EP
Fellowship program in FY 2007/2008.
Continue to expand the CHF program, adding a CHF consult service, and continue to develop a
team of heart failure specialists (Physicians/PA/pharmacy/dietary). Develop a data base for
tracking all CHF pts. Market program as a full service CHF program.
Continue to develop Peripheral Vascular Program. Look at adding a Vascular Medicine
physician.
Work with Emergency Department to develop a Chest Pain Center.
Work with EMS to develop a partnership for a cardiac alert program, transmitting EKG's from
the field.
Continue to focus on growth in satellite offices, work with Lake Shore hospital on plans for new
heart cath lab at Lake Shore
Open a new 14 bed holding unit on 5th floor across from the new labs.
Work with coding/medical records to improve coding procedures/morbidity documentation.
Marketing CV services in 2nd stage of branding campaign.
Additional faculty to support expanding programs to include a CHF Cardiologist, a
Electrophysiology Cardiologists (2), a Interventional Cardiologist, and a Vascular Medicine
physician

Patient Care: As stated above, CV satellite offices continue to expand. Our Lake Shore office provides
cardiovascular care (physician visits as well as diagnostic testing) to Lake City and surrounding
communities. Physicians rotate to the Lake City office Monday-Friday. We signed year 3 of the
agreement with Lake Shore to maintain a practice at this facility and to cover weekend call. Lake Shore
is currently putting in a diagnostic Cath Lab in the facility. Interventional physicians will work in the lab,
treating all patients who need a Cath, and transferring patients to Shands Jacksonville Medical Center
requiring an interventional procedure.

Dr. Howard Baker, a long time cardiologist in the St. Augustine area and a member of our practice,
provided services at the new UF Cardiovascular office in Saint Augustine, Florida at Flagler Hospital. The
office is equipped with all CV diagnostic testing equipment, including a nuclear camera. Dr. Joe
Pensabene joined the practice in November 2006.

We continue with the practice in St. Mary's, Georgia. This office is equipped with diagnostic testing
equipment (ECHO Machine/stress testing). UF cardiologists rotate to the practice Monday through
Friday. They cover office visits as well as hospital consults, at Camden Medical Center. We saw an

Annual Report AY 2007 Cardiology


Cardioloov


Division Chief: Theodore Bass. MD








increase in volume in our St. Mary's office in late 2006, along with an increase in downstream revenue to
Shands Jacksonville Medical Center from this practice in 2006.

On Campus program growth included the Peripheral Program. We continue to increase the number of
patients receiving non-invasive diagnostic peripheral testing (ABIs) and the number of peripheral
invasive procedures performed. We expanded CV inpatient units with the opening of a 24 bed
CCU/Progressive Care Unit. Dr. Doug Chapman was Inpatient Medical Director.

The Electrophysiology Program continues to grow in volume. We are currently recruiting for two
additional Electrophysiologists. Plans were finalized for an arrhythmia service, which will consolidate all
arrhythmia services, M.D.s, support staff, research area, fellows' area and a state-of-the-art conference
room. Construction began December 1, 2006. Plans for an Electrophysiology Fellowship continue.

An invasive cardiology supervisor was hired in 2006 and Dr. Theodore Bass took over as Medical Director
of the Cath labs. Dr. Gimore relocated to Utah in June 2006. Under new leadership, many new
operational policies have been put into place, one being the implementation of a STEMI Stat protocol.

Plans for a new 14 bed holding unit and space for a new inpatient/outpatient nuclear camera were
finalized. Construction began December 1, 2006.

Education: We receive between 400-500 applications per year for five available spots in our Fellowship
Program. Applications are screened eighteen months prior to the start of the program. This past year
we received 519 applicants thru ERAS (Electronic Residency Application Service) of which 55 were
selected for interview. Individuals are invited based on medical school, quality of the medical residency,
USME scores, research performed, and letters of recommendations. Faculty evaluates candidates based
on interpersonal skills, academic potential, and clinical potential.

Fellowship Program changes included additional rotations in adult congenital heart disease, cardiac
surgery, and vascular medicine.

Faculty conducts 4 sessions of Board review for medical residents. Significant changes were made in
CCU rotation assisting the Internal Medicine Residency Program in reacquiring full accreditation.

Fellows passing their boards were at 87%.

Research: The division was involved in several multi-center sponsored research projects in the fields of
heart failure, arrhythmia electrophysiologyy), and coronary artery disease. We currently have 28 active
sponsored research projects being conducted at the Division of Cardiology.

Cardiovascular Imaging Core Laboratories: The Core lab provides quantitative assessment of different
cardiovascular image modalities, including angiography, intravascular ultrasound and magnetic
resonance imaging for clinical studies. Since 2001, the Core lab has been involved in several national
and international clinical trials. Technologies available in the Core lab (UF College of Medicine -
Jacksonville) are unique in the country, including the pioneer worldwide utilization of on-line transfer of
angiographic data via internet in a large clinical trial (STELLAR, see below) and the use of advanced
cardiac MRI quantitative systems.
We are currently developing a quantitative analytical system for optical coherence tomography images to
evaluate atherosclerosis disease.


Annual Report AY 2007 1o Cardiology


Cardioloav


Division Chief: Theodore Bass. MD








Drug-Elutinq Stent Research: Our division has been involved with the first worldwide clinical research
experience in the field of drug-eluting stents. More recently, we coordinated and concluded one of the
largest DES clinical trials in 2006, which involved 1574 patients treated with drug- eluting stents in 43
clinical centers across the U.S (STLLR Trial). We have initiated a new international, multi-center clinical
trial evaluating the role of DES and intravascular ultrasound in the treatment of patients with bifurcation
coronary disease (INSIGHT trial).

In 2006, we initiated international collaboration with Dr. Giugio Guagliumi (Italy) on the evaluation of
vessel wall reaction to overlapping DES using optical coherence tomography.

Imaging: We are exploring the potential of cardiac MRI and multi-slice CT imaging to detect sub-clinical
unstable atherosclerosis disease in the heart and peripheral circulation.

We recently presented the first study validating MRI perfusion techniques compared with invasive
physiologic measurements at the latest American College of Cardiology, March 2006. We established
collaborative research projects evaluating vulnerable plaque (Dr. Juan Granada, Methodist Hospital,
Houston, TX) in a unique animal model of atherosclerosis development.

Our division is currently evaluating the role of MSCT to stratify patients with chest pain, in collaboration
with the Radiology Department.

Angiogenesis/Myocardial Regeneration: Our group was the first in Florida to apply transmyocardial
injection of gene therapy to promote angiogenesis in patients with coronary artery disease. The division
received IRB approval to conduct the first transmyocardial injection of bone marrow derived CD34+
stem cells to promote angiogenesis in patients with coronary artery disease in Florida.

We are currently providing MRI quantitative assessments to various angiogenesis clinical trials
(CORAUTUS, FOCUS-HF, FOCUS-BRIGHT).

The division established collaborative research projects in the field of angiogenesis with the Minneapolis
Heart Institute to evaluate myocardial perfusion in patients who underwent different angiogenesis
therapies.

Progenitor Endothelial Cells: In association with other UF investigators (Mark Segal, M.D., Sergey
Jarikov, Ph.D.), we are investigating the role of circulating progenitor endothelial cells in the
development vascular disease and analyzing nitric oxide production in freshly isolated progenitor cells.

We recently initiated collaboration with Professor Takayuki Asahara, M.D., Ph.D., Director of
Regenerative Medicine and Research, Kobe Institute of Biomedical Research and Innovation, who first
described the presence of circulating progenitor cells in humans. Future plans are to establish a center
for expansion of progenitor cells using a modified colony assay developed by Dr. Asahara's group.

Thrombosis Research: We established a comprehensive laboratory for platelet function studies. In 2006
the division completed the first randomized clinical trial (OPTIMUS) testing higher doses of antiplatelet
therapy in diabetic patients who are resistant to clopidogrel. OPTIMUS-II and OPTIMUS-III, a series of
randomized clinical trials testing the hypothesis of individualized antiplatelet therapy have been initiated.
In the field of platelet function studies, the division is likely one of the most prolific groups worldwide
with > 10 original contributions published in major scientific journals in 2006.


Annual Report AY 2007 Cardiology


Cardioloav


Division Chief: Theodore Bass. MD







Cadola DiiinCif hooeBs.M


LISTING OF FACULTY MEMBERS

New Faculty

Dominick Angiolillo, M.D. Ph.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


The Catholic University of the Sacred Heart Medical School, Italy
The Catholic University of the Sacred Heart Medical School, Italy
University Hospital of Salamanca, Spain/The Policlinico Agostino
Gemelli University Hospital, Italy/San Carlos University Hospital


Joseph Pensabene, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year
Subspecialty training and year
Subspecialty training and year


The Chicago Medical School
Overlook Hospital
Cardiovascular Disease, Northwestern Memorial Hospital
Interventional Cardiology, UCLA Medical Center
Cardiac CT and Cardiac MRI, University of Florida Jacksonville


Current Faculty

Theodore Bass, M.D., Professor and Division Chief


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Brown University
Mayo Clinic
Boston University


Howard Baker, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Ross University School of Medicine, Dominican Republic
Bergen County Hospital
Episcopal Hospital


Douglas Chapman, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Chicago Medical School
University of Missouri
Michael Reese Hospital


Donald Conetta, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training/year


Duke University
Georgetown University
University of Florida


Marco Costa, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Federal University of Minas Gerais, Brazil
Felicio Rocho Hospital
Felicio Rocho Hospital/Thoraxcenter Heart Center


Luis Guzman, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Buenos Aires, Argentina
Churruca-Visca Hospital, Argentina
Institute Cardiovascular Buenos Aires, Argentina


Steve Hsu, M.D., Assistant Professor

Medical School / Graduation date Washington University


Annual Report AY 2007 Cardiology


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Internship/residency and year
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Thomas Jefferson University
Thomas Jefferson University


Steven Lavine, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year

Alan Miller, M.D., Professor

Medical School / Graduation date
Internship/residency and year
Internship/residency and year
Subspecialty training and year


Temple University
Temple University
Temple University


University of Pittsburgh
Mount Sinai
George Washington University
Cleveland Metropolitan Hospital


David Nabert, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


UMDNJ New Jersey Medical School
Hackensack University Medical Center
Ochsner Medical Foundation


Robert Percy, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year
Subspecialty training and year


University of Mississippi
University of Mississippi
Joslin Clinic
Mass General Hospital


Norbert Wilke, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Internship/residency and year
Subspecialty training and year


Friedrich-Alexander University, Germany
Friedrich-Alexander University, Germany
Friedrich-Alexander University, Germany
University of Minnesota


Martin Zenni, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Chicago
Tufts University
Harvard Medical School


PUBLICATIONS

Angiolillo DJ., Fernandez-Ortiz A., Bernardo E., Ramirez C., Sabate M., Jimenez-Quevedo P, Hernandez R.,
Moreno R., Escaned J., Alfonso F., Baiuelos C., Costa MA, Bass TA, Macaya C. Influence of Aspirin Resistance on
Platelet Function Profiles in Patients on Long-term Aspirin and Clopidogrel After Pecutaneous Coronary
Intervention. Am J Cardiol 2006; 97:38-43.

Angiolillo D.J., Fernandez-Ortiz A., Bernardo E., Ramirez C., Sabate M., Jimenez-Quevedo P, Hernandez R.,
Moreno R., Escaned J., Alfonso F., Baiuelos C., Costa MA, Bass TA, Macaya C. Clopidogrel withdrawal is
associated with pro-inflammatory and pro-thrombotic effects in diabetic patients with coronary artery disease.
Diabetes 2006;55:780-4.

Angiolillo D3. Futamatsu K, Costa MA, Bass, TA. How to develop antiplatelet treatment for drug eluting stent?
International Review of Thrombosis 2006; 1: 48-57.


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Cardioloov


Division Chief: Theodore Bass. MD


Annual Report AY 2007


Cardiology









Angiolillo D.J., Bernardo E., Ramirez C., Costa MA, Sabat6 M., Jimenez-Quevedo P, Hernandez R., Moreno R.,
Escaned J., Alfonso F., Baiuelos C., Bass TA, Macaya C Fernandez-Ortiz A. Insulin Therapy is Associated with
Platelet Dysfunction in Patients with Type 2 Diabetes Mellitus on Dual Oral Antiplatelet Treatment. J Am Coil Cardiol
2006; 48:298-304.

Angiolillo D3, Fernandez-Ortiz A, Bernardo E, Ramirez C, Cavallari U, Trabetti E, Sabate M, Hernandez R, Moreno
R, Escaned J, Alfonso F, Banuelos C, Costa MA, Bass TA, Pignatti PF, Macaya C. Contribution of Gene Sequence
Variations of the Hepatic Cytochrome P450 3A4 Enzyme to Variability in Individual Responsiveness to Clopidogrel.
Arterioscler Thromb Vasc Biol. 2006; 26:1895-900.

Angiolillo D3, Singh D. Clopidogrel for up to one year after PCI is cost-effective for people with acute coronary
syndromes. Evid Based Cardiovasc Med. 2006; 10:116-8.

Angiolillo D3. Tackling the diabetic platelet: is high clopidogrel dosing the answer? Journal of Thrombosis and
Haemostasis 2006; 4:2563-5.

Fernandez Oritz A, Angiolillo D3. Use of oral antiplatelet agents during percutaneous coronary interventions. Rev
Esp Cardiol 2006 (Supplement I).

Alfonso F, Angiolillo D3. Platelet Function Assessment to Predict Outcomes after Coronary Interventions: Hype or
Hope? J Am Coil Cardiol 2006; 48:1751-4.

Bernardo E, Angiolillo D3, Ramirez C, Cavallari U, Trabetti E, Sabate M, Hernandez R, Moreno R, Escaned J,
Alfonso F, Banuelos C, Costa MA, Bass TA, Pignatti PF, Macaya C, Fernandez-Ortiz A. Influence of the CD14 C(-
260)T Promoter Polymorphism on C-Reactive Protein Levels in Patients with Coronary Artery Disease. Am J Cardiol
2006; 98:1182-4.

Bernardo E, Angiolillo D3, Ramirez C, Cavallari U, Trabetti E, Sabate M, Hernandez R, Moreno R, Escaned J,
Alfonso F, Banuelos C, Costa MA, Bass TA, Pignatti PF, Macaya C, Fernandez-Ortiz A. Lack of Association
Between Gene Sequence Variations of Platelet Membrane Receptors and Aspirin Resistance Defined by the PFA-100
System in Patients with Coronary Artery Disease. Platelets 2006; 17:586-90.

Costa MA, Sabate M, Angiolillo D3, Jimenez-Quevedo P, Teirstein P, Carter A, Leon MB, Moses J, Zenni M,
Yakubov S, Guzman LA, Gilmore P, Macaya C, Bass TA. Intravascular Ultrasound Characterization of the Black
Hole Phenomenon after Drug-eluting Stent Implantation. Am J Cardiol 2006; 97:203-6.

Moreno R, Conde C, Perez-Vizcayno MJ, Villarreal S, Hernandez-Antolin R, Alfonso F, Banuelos C, Angiolillo D3,
Escaned J, Fernandez-Ortiz A, Macaya C. Prognostic impact of a chronic occlusion in a noninfarct vessel in patients
with acute myocardial infarction and multivessel disease undergoing primary percutaneous coronary intervention. J
Invasive Cardiol. 2006;18:16-9.

Bass TA. DES: technique still matters. Catheter Cardiovasc Interv. 2006;67:10-1.

Cervinka P, Costa MA, Angiolillo D3, Spacek R, Bystron M, Kvasnak M, Veselka J, Nanda H, Futamatsu H,
Futamatsu K. Head-to-head comparison between sirolimus-eluting and paclitaxel-eluting stents in patients with
complex coronary artery disease: An intravascular ultrasound study. Catheter Cardiovasc Interv. 2006; 67:846-51.

Jimenez-Quevedo P, Sabate M, Angiolillo D3, Costa MA, Alfonso F, G6mez-Hospital JA, Hernandez-Antolin R,
Baiuelos C, Goicolea J, Fernandez-Aviles F, Bass TA, Escaned J, Moreno R, Fernandez C, Macaya C. Three-
dimensional intravascular ultrasound evaluation of the vascular effects of sirolimus-eluting versus bare metal stents
in diabetic patients: Insights from the DIABETES trial. J Am Coil Cardiol 2006; 47:2172-9.

Bass TA. "Menage a trois" or "No Mas" Catheter Cardiovasc Interv. 2006;67:377-378.


Annual Report AY 2007 Cardiology


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Division Chief: Theodore Bass. MD






Cardiology Division Chief: Theodore Bass, MD

Futamatsu H, Sabat6 M, Angiolillo DJ, Jimenez-Quevedo P, Corros C, Morikawa-Futamatsu K, Alfonso F, Jiang J,
Cervinka P, Hernandez-Antolin R, Macaya C, Bass TA, Costa MA. Characterization of Plaque Prolapse after Drug-
eluting Stent Implantation in Diabetic Patients: A Three-dimensional Volumetric Intravascular Ultrasound Outcome
Study. J Am Coil Cardiol 2006; 48:1139-45.

Jimenez-Quevedo P, Sabate M, Angiolillo DJ, Alfonso F, Hernandez-Antolin R, Gomez-Hospital JA, Sanmartin M,
Banuelos C, Moreno R, Escaned J, Fernandez C, Costa MA, Fernandez-Aviles F, Macaya C. Efficacy of Sirolimus-
Eluting Stent Implantation in Diabetic Patients With Very Small Vessels ( DIABETES Trial. Rev Esp Cardiol. 2006;59:1000-1007.

Ortiz AA. Lavine S3. The index of myocardial performance and aortic regurgitation: the influence of a volume
overload lesion. Anat. J Cardiol 2006; 6:115-120.

Rolandi F, Guzman L, Rubinstein F, Gabay JM, Sarmiento R, Perez de Arenaza D, de Miguel R, Alvarez J, Navarro
Estrada JL. N-terminal-pro brain natriuretic peptide predicts unfavorable prognosis in patients with acute coronary
syndromes and preserved LV function. Rev Argentina de Cardiol. 2006;74:19-27

Navarro Estrada JL, Rubinstein F, Cecilia Bahit M, Rolandi F, Perez de Arenaza D, Gabay JM, Alvarez J, Sarmiento
R, Rojas Matas C, Sztejfman C, Tettamanzi A, de Miguel R, Guzman LA. NT-pro brain natriuretic peptide predicts
complexity and severity of the coronary lesions in patients with non-ST-elevation acute coronary syndromes. Am
Heart J. 2006;151:1093 el-7.

Kurian KC, Chiong JR, Rai P, Miller AB. Statins and heart failure-effects beyond cholesterol lowering. J Card Failure
2006;12:473-8.

Lavine S3, Lavine JA. The effect of acute hypertension on left ventricular diastolic pressures in a canine model of left
ventricular dysfunction with preserved ejection fraction and elevated LV filling pressures. J Am Soc Echo 2006;
19:1350-8.

Corbisiero R, Lee MA, Nabert DR, Coman JA, Breiter DJ, Schwartz M, McKittrick E, Zhang Y. Performance of a new
single-chamber ICD algorithm: discrimination of supraventricular and ventricular tachycardia based on vector
timing and correlation. Europace. 2006 Dec;8(12):1057-61.

Chiong JR, Miller AB, Monterio C et al: Syncope: a case of vein graft rupture. Clin Cardiol Images
2006;29:512.

Panse P, Klassen C, Panse N, Siuciak A, Rickers C, Jerosch-Herold M, Wilke NM. Magnetic resonance quantitative
myocardial perfusion reserve demonstrates improved myocardial blood flow after angiogenic implant therapy. Int J
Cardiovasc Imaging. 2006 Jul 20; [Epub ahead of print]

Jerosch-Herold M, Muehling O, Wilke N. MRI of myocardial perfusion. Semin Ultrasound CT MR. 2006;27:2-10.

Klassen C, Nguyen M, Siuciak A, Wilke NM. Magnetic resonance first pass perfusion imaging for detecting
coronary artery disease. Eur J Radiol. 2006;57:412-6.

C Klassen, M Nguyen, F von Ziegler, A Siuciak, N Wilke. Software analyzes MR first-pass perfusion data.
Diagnostic Imaging 2006 (in press).

Costa MA, Rai P, Guzman LA. Renal Artery Disease. Brazilian Journal of Interventional Cardiology 2006 (in
press).

Ilegbusi JO, Teuma EV, Costa MA. A Fluid-Structure Interaction Index of Coronary Plaque Rupture. Journal of
Biomechanical Engineering 2006 (in press)


Annual Report AY 2007 Cardiology









Serebruany V, Malinin A, Pokov A, Arora U, Atar D, Angiolillo D3. Effects of escalating doses of tirofiban on
platelet aggregation and major receptor expression in diabetic patients: Hitting the TARGET in the TENACITY trial?
Thromb Res. 2007: 119: 175-181.

Pavlovic C, Futamatsu H, Angiolillo D3, Guzman LA, Wilke N, Siragusa D, Wludyka P, Percy R, Northrup M,
Bass TA, Costa MA. Quantitative Contrast Enhanced Magnetic Resonance Imaging for the Evaluation of Peripheral
Arterial Disease: A Comparative Study versus Standard Digital Angiography. J Cardiovasc Imaging 2007 (in press).

Costa MA, Sabate M, Angiolillo D3, Hu P, Jimenez-Quevedo P, Corros C, Alfonso F, Hernandez-Antolin R, Macaya
C, Bass TA. Relocation of Minimal Luminal Diameter After Bare Metal and Drug-Eluting Stent Implantation:
Incidence and Impact on Angiographic Late Loss. Catheter Cardiovasc Interv. 2007 (in press)

Costa M, Sabate M, Staico R, Alfonso F, Seixas AC, Albertal M, Crossman A, Angiolillo D3, Zenni M, Sousa JE
Macaya C, Bass TA. Anatomical and Physiologic Assessments in Patients with Small Coronary Artery Disease: Final
Results of the PHANTOM Trial. Am Heart J 2007 (in press).

Moreno R, Fernandez C, Sanchez-Recalde A, Galeote G, Calvo L, Alfonso F, Hernandez R, Sanchez-Aquino R,
Angiolillo D3, Villarreal S, Macaya C, Lopez-Sendon JL. Clinical impact of in-stent late loss after drug-eluting
coronary stent implantation. Eur Heart J 2007 (in press).

Lavine S3, Mansouri V. Effect of pericardial constraint on the index of myocardial performance in a canine model of
left ventricular dysfunction. Echocardiography 2007 (in press).

Lavine S3. Effect of changes in contractility on the index of myocardial performance in the dysfunctional left
ventricle. Cardiovascular Ultrasound 2007 (in press).

Angiolillo D3. ADP receptor antagonism: what's in the pipeline? Am J Cardiovasc Drugs 2007 (in press).

Angiolillo D.J., Bernardo E., Costa MA, Sabat6 M., Alfonso F., Bass TA, Macaya C, Fernandez-Ortiz A. Platelet
dysfunction associated to insulin therapy in patients with type 2 diabetes: please do not throw the baby out with
the bath water! J Am Coil Cardiol 2007 (in press).

Angiolillo D.J., Fernandez-Ortiz A, Bernardo E., Alfonso F., Macaya C, Bass TA, Costa MA. Variability in
Individual Responsiveness to Clopidogrel: Clinical Implications, Management and Future Perspectives. J Am Coil
Cardiol 2007 (in press).

Angiolillo D3. Antiplatelet therapy in type 2 diabetes mellitus. Current Opinion in Endocrinology and Diabetes
2007 (in press).

G6mez-Moreno S, Sabate M, Jimenez-Quevedol P, V6zquez P, Alfonso F, Angiolillo D3, Hernandez-Antolfn R,
Moreno R, Baiuelos C, Escaned J, Macaya C. Iatrogenic dissection of the ascending aorta following heart
catheterization: incidence, management and outcome. Eurolnterv 2007 (in press).

Box LC, Angiolillo D3, Suzuki N, Box LA, Jiang J, Guzman L, Zenni MA, Bass TA, Costa MA. Variability of
Atherosclerotic Plaque Characteristics in Human Coronary Arteries disease: a Three-dimensional Intravascular
Ultrasound Study. Catheter Cardiovasc Interv. 2007 (in press).

Angiolillo D.J., Desai B, Shoemaker, Yuan H, Bernardo E, Charlton R, Guzman L, Zenni M, Bass TA, Costa
MA. A randomized trial of different clopidogrel maintenance doses in patients with diabetes mellitus and coronary
artery disease. Results of the OPTIMUS-1 trial. (Optimizing Antiplatelet Therapy In diabetes MellitUS). Circulation
2007 (submitted).

Costa MA, Shoemaker S,, Futamatsu H, Klassen C, Angiolillo D3, Nguyen M, Siuciak A, Gilmore P, Zenni MM,
Guzman L, Bass TA, Wilke N. Myocardial Perfusion Reserve Determined by Magnetic Resonance Perfusion

Annual Report AY 2007 Cardiology


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Division Chief: Theodore Bass. MD






Cardiology Division Chief: Theodore Bass, MD

Correlates with Invasive Physiologic and Anatomical Assessments of Coronary Artery Disease. J Am Coil Cardiol 2007
(submitted)

Wainstein MV; Costa MA; Ribiero JP; Zago AJ; Campos MR, Courtney BK, Ghazarossian VE, Tsugita RS, Sadaat V,
Rogers C. Vulnerable plaque detection by temperature heterogeneity measured with a guidewire system: clinical,
intravascular ultrasound, and histopathologic correlates. Am J Cardiol 2007 (submitted).


HONORS AND AWARDS

Stephen J. Lavine, M.D.
2006 University of Florida Exemplary Teaching Award.

Dominick Angiolillo, M.D., Ph.D.
2006 Florida State "Stop the Heart" Researcher of the Year Award Florida Heart Institute/ Florida Chapter of the
American College of Cardiology.

Winner of the Leonardo da Vinci Scholarship of the European Community (Brussels, 1998).

Young Investigator Award of the Italian Society of Cardiology in basic cardiological research (Rome, December
1997, 1998, 199, 2001, 2002).

Winner of the Leonardo da Vinci Wealth Programme" Scholarship of the European Community (Brussels 2001).

Winner of Investigator Award at the Fifth International Congress on Nuclear Cardiology (Vienna, 2001)

Young Investigator Award for the Best Scientific Contribution in Interventional Cardiology of the Italian Society of
Interventional Cardiology (GISE, Verona, October 2002)

Winner of the Training Fellowship in Interventional Cardiology of the European Society of Cardiology (Berlin, August
2002).

Winner of the Cardiovascular Research Award on Thrombosis sponsored by AVENTIS and the Italian Society of
Cardiology (Rome December 2002).

Winner of the Marie Curie Individual Fellowship of the European Community for Post-Graduate Cardiovascular
Research (Brussels, December 2002).

Investigator Award Finalist of the Spanish Society of Cardiology (Madrid and Seville, October 2002, 2003)

Investigator Award of the Spanish Society of Thrombosis (Salamanca, October 2003).

Cardiovascular Research Foundation Young Investigator Award in Interventional Cardiology (Washington, DC;
September 2003).

Young Investigator Award in Thrombosis of the European Society of Cardiology (Munich 2004)

Young Investigator Award in Thrombosis of the European Society of Cardiology (Stockholm 2005)

Marco Costa, M.D., PhD.
2003 Researcher of the Year, American College of Cardiology Florida Chapter, Orlando, FL.

2002 Best Abstract Award, Annual Meeting of the Brazilian Society of Intervention Cardiology, Rio de Janeiro,
Brazil.
Annual Report AY 2007 Cardiology











2000 Best Abstract Award, Annual Meeting of the Vasconavarra-Aragonesa Society of Cardiology, Spain.

1999 Best International Clinical Trial. III Congress of the Latin America Society of Interventional Cardiology
(SOLACI), Chile.

Theodore A. Bass, M.D. (2 yrs)
University of Florida, Researcher of the Year (2004)

Jacksonville Business Journal; Super Scientist award (2005)



CLINICAL ACTIVITIES


Inpatient activity AY 06/07
CV In PT admissions 1,366
Cardiology discharges 2,113
Observations 254

Outpatient activity
Physician clinic visits 9,729
Cardiac ultrasounds 9,919
Cardiac nuclear studies 2,151
EKGs 45,783
Stress tests 3,561
Heart caths 2,066
EP procedures 199
Device placements 310
Cardiac rehab visits 3,694


CONTRACTS AND GRANTS


RESEARCH
Sponsor Date Begun Study
Eli Lilly 6/05 TIMI38
Eli Lilly 7/06 SWAP
Eli Lilly 11/06 TIMI44
HCRI 3/06 Resistor
Medtronic 1/05 Endeavor
Otsuka 2/06 Eclipse
Sanofi-Synthelabo 7/05 Stradivarius
Corautus Genetics 7/05 Genasis
Baxter 7/06 ACT34
Abbott Vacular 6/06 ZoMaxxII
Pfizer 11/03 PfizerA5901005
Flowmedica 6/05 BNP-002
Abbott Vascular 7/06 Exact
NHLBI 12/06 Coral
FoxHollow 4/06 Leap
Medtronic 3/05 Reverse
Guidant 3/05 SitelineAPL
Guidant 4/05 Easytrak4
St. Jude Medical 9/05 PAS
St. Jude Medical 9/05 VER
St. Jude Medical 9/05 AFS
Irvine Biomedical 11/05 CoolPath
St. Jude Medical 11/05 RethinQ


Cardioloov


Division Chief: Theodore Bass. MD


Annual Report AY 2007


Cardiology










Zealand Pharma 5/06 Zealand

Research Grant Total: $1,619,381.10

CONTRACTS & GRANTS, CARDIOVASCULAR IMAGING CORE LABORATORIES AND BASIC RESEARCH
Sponsor Date Role of Nominee Total Award
Cordis Corporation 2003-2006 STLLR Trial, PI Responsibility, Fellow Grant and Core Lab $725,000

Cordis Corporation 2005-2006 Director, Educational Seminars $40,000

Cordis Corporation 2005-2006 Diabetes II Trial, Core Lab $93,000

Sorin Biomedical Cardio 2005-2006 Diabetes III Trial, Core Lab $226,530

XTENT Inc 2005-2006 Custom I Trial, Core Lab $17,200

XTENT Inc 2006-2007 Custom II Trial, Core Lab $46,000

XTENT Inc 2006-2007 Custom III Trial, Core Lab $54,000

Pathway Medical Technologies 2006-2007 The Pathway PV Trial, Core Lab $120,000

Corautus, Inc 2006 Genasis MRI Trial, Core Lab $3,200

NIPRO Medical Corporation 2005-2006 Principal Investigator $15,000

Cordis Japan 2006-2011 Unrestricted Educational Grant, Core Lab $300,000

Japan Gunma 2006-2007 Administration Fee for Research PDA, Core Lab $20,000

Boston Scientific 2006 Educational Program, Core Lab $10,000

University of Florida 2005-2006 Circulating Endothelial Progenitor Cell... $10,000

Funding Source Date Research Project Total Award
University of Florida 2005-2006 Circulating Endothelial Progenitor Cell and its Association with $10,000
Coronary Artery Disease in Patients with Diabetes

University of Florida 2005-2006 A Randomized Comparison Between Two Different Clopidogrel $10,000
Maintenance Doses in Patients with Diabetes Mellitus and Coronary
Artery Disease

University of Florida 2005-2006 Clopidogrel Effects on Neointimal Hyperlasia Following Coronary Stent $5,000
Implantation in Diabetic Patienrs

University of Florida 2005-2006 Renal Vascular Intervention in a Cohort of Heart Failure Patients $5,000

University of Florida 2005-2006 Investigation of Current Clinical Patterns and Outcome of Patients with $5,000
Heart Failure

University of Florida 2005-2006 Correlation Between Cardiac MRI Perfusion and Invasive Physiologic $5,000
Coronary Assessments

University of Florida 2005-2006 Characterization of Carotid Atherosclerotic Artery Disease Using High $5,000
Resolution Magnetic Resonance Angiography: Comparison with 3D
Intravascular Ultrasound (IVUS).

University of Florida 2005-2006 Significance of Normal CK to CKMB Ratio and Elevated Troponin in $2,040
Patients Without Chest Pain


Annual Report AY 2007 Cardiology


Cardioloov


Division Chief: Theodore Bass. MD


Annual Report AY 2007


Cardiology

























































































28









DIVISION OF ENDOCRINOLOGY
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

Academic year 2006 was characterized by stabilization of the Division's clinical practice. The delivery of
high quality patient care continued. Plans for the addition of three more endocrinologists were made and
brought to fruition by the hiring of the additional endocrinologists who will start in 2007. Finally the
endocrine diabetes clinics were relocated in the new outpatient practice facility. A new initiative to
improve the diabetes care of hospitalized diabetic patients at Shands Jacksonville was undertaken.

Patient Care: The Division provides inpatient and outpatient consultation for the University of Florida
Jacksonville campus and satellite offices as well as for referring physicians in private practice. Dr. Lavine
and physician assistant Don Reed are the current core clinical faculty. All clinical endocrinology problems
are addressed by the Division, including diabetes, thyroid disease, adrenal disease and all other
endocrinopathies. Thyroid needle biopsy procedures and radioactive iodine therapy for hyperthyroidism
and thyroid malignancies are offered by the division. The Division also coordinates and American
Diabetes Association accredited outpatient education service that includes a certified diabetic educator
(Evelyn Schumacher, RD, CDE).

Education: The Division of Endocrinology and Diabetes provides a key educational experience for
medical students and residents in Internal Medicine. Trainees from both areas participate in a consult
month of endocrinology, and are mentored by Dr. Lavine. Division faculty also participate in resident
morning report, the noon lecture series, Departmental Grand Rounds, and designated slots for
Endocrinology board review sessions. In addition, the Division facilitates continuing medical education in
endocrinology and diabetes through lectures and seminar with community and University of Florida
satellite physicians.

Research: Research activities are limited by the current size of the Division. However, initiatives are
underway to participate as a study in several national clinical trials. As faculty recruitment goals are met,
this facet of the academic mission will become attainable.


LISTING OF FACULTY MEMBERS

Robert Lavine, M.D., Associate Professor and Division Chief

Medical School / Graduation date George Washington University 1966
Internship/residency and year Boston City Hospital 1968
Subspecialty training and year Harvard Medical School 1970

Arshag Mooradian, M.D., Professor and Department Chair

Medical School / Graduation date American University of Beirut 1980
Internship/residency and year American University of Beirut 1982
Subspecialty training and year University of Minnesota 1985

Kent Wehmeier, M.D., Associate Professor

Medical School / Graduation date University of Missouri Columbia 1988
Internship/residency and year Barnes-Jewish Hospital 1991
Subspecialty training and year Saint Louis University School of Medicine 1993


Annual Report AY 2007 Endocrinology


Endocrinoloov


Division Chief: Robert L. Lavine. MD









PUBLICATIONS

Marston WA, Mooradian AD (site PI) for the Dermagraft Diabetic Foot Ulcer Study Group. Risk factors associated with healing
chronic diabetic foot ulcers: The importance of hyperglycemia. Ostomy Wound Manage. 52: 26-39, 2006.

Horani MH, Haas MJ, Mooradian AD. Suppression of hyperglycemia-induced superoxide formation and endothelin-1 gene
expression by carvedilol. Am. J. Therapeutics. 213:2-7, 2006.

Mooradian AD, Haas MJ, Wadud K. Ascorbic acid and a-tocopherol down regulate apolipoprotein AI gene
expression in HepG2 and Caco-2 cell lines. Metabolism: Clinical and Experimental 55:159-167, 2006.

Horani MH, Haas MJ, Mooradian AD. Saturated, unsaturated, and trans fatty acids modulate oxidative burst
induced by high dextrose in human umbilical vein endothelial cells. Nutrition 22:123-127, 2006.

Mooradian AD, Haas MJ, Wong NCW. The effect of select nutrients on serum high density lipoprotein cholesterol
and apolipoprotein A-I levels. Endocrine Reviews 27:2-16, 2006.

Mooradian AD. Antioxidants and Diabetes. Nestle Nutr Workshop Ser Clin Perform Programme. 11:107-125,
2006.

Steiner G et al. for the BARI 2D Trial Investigators. Statement of the problem. Am. J. Cardiol 97[suppl]:3G-8G,
2006. Mooradian AD site PI and member of the Steering committee.

Brooks MM et al. for the BARI2D Trial Investigators. Hypotheses, design, and methods for the Bypass Angioplasty
Revascularization Investigation 2 diabetes (BARI 2D) Trial. Am. J. Cardiol 97[suppl]:9G-19G, 2006. Mooradian
AD site PI and member of the Steering committee.

Magee MF, Isley WL for the BARI2D Trial Investigators. Rationale, design and methods for glycemic control in the
Bypass Angioplasty Revascularization Investigation 2 diabetes (BARI 2D) Trial. Am. J. Cardiol 97[suppl]:20G-30G,
2006. Mooradian AD site PI and member of the Steering committee.

Barsness GW, Gersh BJ, Brooks MM, Frye RL for the BARI2D Trial Investigators. Rationale for the revascularization
arm of the Bypass Angioplasty Revascularization Investigation 2 diabetes (BARI 2D) Trial. Am. J. Cardiol
97[suppl]:31G-40G, 2006. Mooradian AD site PI and member of the Steering committee.

Albu J, Gottlieb SH, August P, Nesto R, Orchard TJ for the BARI2D Trial Investigators. Modifications of coronary risk
factors. Am. J. Cardiol 97[suppl]:41G-52G, 2006. Mooradian AD site PI and member of the Steering committee.

Sobel BE for the BARI2D Trial Investigators. Ancillary studies in the Bypass Angioplasty Revascularization
Investigation 2 diabetes (BARI 2D) Trial: Synergies and opportunities. Am. J. Cardiol 97[suppl]:53G-58G, 2006.
Mooradian AD site PI and member of the Steering committee.

Hlatky MA, Meslop KA, Boothroyd DB for the BARI2D Trial Investigators. Economic evaluation of alternative
strategies to treat patients with diabetes mellitus and coronary artery disease. Am. J. Cardiol 97[suppl]:59G-65G,
2006. Mooradian AD site PI and member of the Steering committee.

Case CC, Mooradian AD. Elevated plasma chromogranin A levels secondary to assay interference: A source of
diagnostic confusion. Endocrine Practice 12:476-477, 2006.

Haas MJ, Horani MH, Parseghian SA, Mooradian AD. Statins prevent dextrose-induced endothelial barrier
dysfunction possibly through inhibition of superoxide formation. Diabetes 55:474-479, 2006.

Morgentaler A for the National Tadalafil Study Group. Efficacy and safety of tadalafil across ethnic groups and
various risk factors in men with erectile dysfunction: use of a novel non-inferiority study design. J. Sexual Med. 3:
492-503, 2006.

Annual Report AY 2007 Endocrinology


Endocrinoloov


Division Chief: Robert L. Lavine. MD










Beers A, Haas MJ, Wong NCW, Mooradian AD. Inhibition of apolipoprotein AI gene expression by tumor necrosis
factor a: Roles for MEK/ERK and JNK Signaling. Biochemistry 45: 2408-2413, 2006.

Mooradian AD, Korenman SG. Management of the cardinal features of andropause. Am. J. Therapeutics 13: 145-
160, 2006.

Mooradian AD, Bernbaum M, Albert SG. Narrative review: A rational approach to starting insulin therapy. Ann.
Intern. Med. 145:125-34, 2006.

Mooradian AD. The dietary regulation of high density lipoprotein cholesterol. Commentary May 2006,
International Atherosclerosis Society, http://www.athero.ora; accessed July 15, 2006.

Hachem SB, Mooradian AD. Familial dyslipidaemias: An overview of genetics, pathophysiology and
management. Drugs 66: 1949-1969, 2006.

Bantle JP, Wylie-Rosett J, Albright AL, Apovian CM, Clark NG, Franz MJ, Hoogwerf BJ, Lichtenstein AH, Mayer-Davis
E, Mooradian AD, Wheeler ML. American Diabetes Association. Nutrition Recommendations and Interventions for
Diabetes-2006 A position statement of the American Diabetes Association. Diabetes Care 29:2140-2157, 2006.


CLINICAL ACTIVITIES


Inpatient Activity AY 06/07
Number of IP Consults 75

Outpatient Activity
Clinic Visits 3308


CONTRACTS AND GRANTS


Annual Report AY 2007


Principle Sponsor Date Title
Investigator
Mooradian A NHLBI; National 3/1/01- Bypass Angioplasy Revascularization Investigation in type 2 Diabetes
Institute of //
Health

Mooradian A NIH; National Formulated Phytosterols A New Treatment for Benign Prostatic Hyperplasia
Institute on 2007-2009
Aging I

Mooradian A Shands/UF CME 2007-2008 Impact of Diabetes Education on Outcome of Hospitalized Diabetic Patients


Endocrinoloov


Division Chief: Robert L. Lavine. MD


Endocrinology

























































































32








DIVISION OF GASTROENTEROLOGY
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Division saw outpatients at the on-campus Ambulatory Care Center (ACC), Emerson
Gastroenterology Clinic (Emerson), Northside Multi-specialty Clinic (Northside), Shands Jail Clinic, UF
Jacksonville Faculty Clinic, VA Clinic in Jacksonville, Duval County Health Department, Beaches Digestive
Cinic, and the Southside Digestive Clinic.

Ambulatory motility studies, capsule endoscopy, and diagnostic breath tests were performed at Emerson.
Endoscopy procedures were performed at Shands Jacksonville Medical Center.

Patient Care: The patient care aspect of the academic mission is pursued by the Division through four
University of Florida clinics, the provision of inpatient consult services at Shands Jacksonville, inpatient
and outpatient GI services at Baptist Medical Center Beaches and St. Luke's Hospital, as well as
providing outpatient services at the Jacksonville Veterans Administration Medical Center, and the Duval
County Department of Health. The Division continues to be the leader in Northern Florida in the
treatment of viral hepatitis and staffs a gastrointestinal motility laboratory that is among the most active
in the state.

Education: The division was involved in teaching for the residency program. Coordinated by Dr. Ravi
Kottoor, the division conducted resident rotations for inpatient gastroenterology consults and ambulatory
gastroenterology. The division taught residents in morning report, noon resident conference, and
internal medicine grand rounds.

The division conducted a gastroenterology fellowship program which consists of two fellows a year for
three years. The program was pleased to continue its 100% board passage rate by previous year's
graduates. Work is underway to prepare for an upcoming accreditation site visit.

Research: Divisional research activities include clinical trials, and giving presentations at regional and
national meetings. The Division will continue to mentor and guide residents and fellows in their research
endeavors and will focus on continued recruitment efforts for faculty with skill sets in hepatology and
therapeutic endoscopy. The GI fellowship program anticipates further successes in recruiting high
quality candidates and the faculty plans continued interaction and mentoring of resident research
activities.


LISTING OF FACULTY MEMBERS

Louis Lambiase, M.D., Assistant Professor and Division Chief

Medical School / Graduation date University of Miami 1987
Internship/residency and year University of Pittsburgh 1990
Subspecialty training and year University of Florida 1992

Robert Bass, M.D., Assistant Professor

Medical School / Graduation date Medical College of Georgia 1988
Internship/residency and year University of South Alabama 1991
Subspecialty training and year University of Florida Jacksonville 1993


Annual Report AY 2007


Gastroenteroloov


Division Chief: Louis Lambiase. MD


Gastroenterology







G e D


Byron Kolts, M.D., Professor

Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Rochester
Dartmouth Medical School/University of Vermont
University of Florida


Ravi Kottoor, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training/year


Kasturba Medical College, India
Ottawa Civic Hospital
Dalhousie University, Canada


Juan Munoz, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Universidada Complutense, Spain
University of Florida Jacksonville
University of Florida Jacksonville


Edward Partyka, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Ohio State University
Mount Carmel Medical Center
University of Arizona, VA Hospital


Paul Sievert, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Miami
Medical College of Virginia
University of Florida Jacksonville


Kenneth Vega, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Cornell University Medical College
Boston University School of Medicine
Temple University Hospital


PUBLICATIONS

Lambiase L, Harrison J. The impact of GME on Teaching Hospital Efficiency. Journal of Health Care Finance.
Accepted 5/10/2007 for publication in Fall 2007.

Vega K3, Rabaa E, Jamal MM. Lower esophageal sphincter pressure and distal esophageal body function between
Hispanic Americans and non-Hispanic whites are equivalent J Clin Gastroenterol. 2007 Feb;41(2):141-4.

Rascon-Aguilar, I; Pamer, M; Wludyka, P; Nahman, S, Lambiase, L; Cury, J Coultas, D; Vega, K The Role of
Gastroesophageal Reflux in Exacerbations of Chronic Obstructive Pulmonary Disease Chest. 2006
Oct;130(4):1096-101

Balan V, Nelson DR, Sulkowski MS, Everson GT, Lambiase LR, Wiesner RH, Dickson RC, Post AB, Redfield RR,
Davis GL, Neumann AU, Osborn BL, Freimuth WW, Subramanian GM. A Phase I/II study evaluating escalating
doses of recombinant human albumin-interferon-alpha fusion protein in chronic hepatitis C patients who have failed
previous interferon-alpha-based therapy. Antivir Ther. 2006;11(1):35-45.


Gupta, R, Munoz, JC, Garg, P, Masri, G,Nahman, NS, Lambiase, LR. Mediastinal Pancreatic Pseudocyst A Case
Report and Review of the Literature Medscape General Medicine. 2007;9(2):8


Annual Report AY 2007


1964
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1991
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2004



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1988
1991
1995


Gastroenteroloov


Division Chief: Louis Lambiase. MD


Gastroenterology









Munoz JC, Lambiase LR,. Hereditary Colon Cancer in Katz J ed Medicine OB-GYN, Psychiatry and Surgery
Emedicine.com 2007 Accepted for e-publication

Habashi SL, Lambiase LR, Anand MK, Mishark, KJ, Nguyen C, Dubin Johnson Syndrome in Katz J ed Medicine,
OB-GYN, Psychiatry and Surgery Emedicine.com 2006

Cole, M, Lambiase LR. Updates and Future Trends in Colorectal Cancer Screening. Northeast Florida Medicine
2007;58(1):27-32.

DiTeodoro LA, Reddy S, Vega IK. Gastrointestinal manifestations of ovarian
hyperstimulation syndrome. Am J Gastroenterol 2006; 101 supply) : S289.

DiTeodoro LA, Reddy S, Vega I3. Gastrointestinal stromal tumor: an atypical presentation of
upper gastrointestinal bleeding. Am J Gastroenterol 2006; 101 supply) : S255-S256. (Poster presentation, ACG
2006)


HONORS AND AWARDS

Drs. Bass and Lambiase were noted as "Top Doctors" by Jacksonville Magazine
Dr. Lambiase was awarded notice as one of the "Best Doctors" in America


Degrees Earned:
Louis Lambiase:


Master of Health Administration, August 2006


CLINICAL ACTIVITIES

Data is not available for all sites; however the activity detail is as follows:


Clinic Visits
Site Visits
ACC 1704
Emerson 4900
Faculty Clinic 443
Northside 1669
Jail Clinic 53

Procedures at Emerson
Procedure Visit
Remicade Infusion 111
Esophageal Manometry 103
Capsule Endoscopy 37
Anorectal Manometry 35
24 Hr pH Probe 59
Breath Tests 105

Endoscopy Procedures
Procedure Number
Upper Endoscopy 1669
Colonoscopy 2705
ERCP 107
Upper Endoscopic Ultrasound 78
Lower Endoscopic Ultrasound 14
Liver Biopsy 69


Gastroenteroloov


Division Chief: Louis Lambiase. MD


Annual Report AY 2007


Gastroenterology









Small Bowel Enteroscopy 11
Flexible Sigmoidoscopy 264



GRANTS AND CONTRACTS

Principal Title Amount Funded Source Total Awarded
Investigator (July 2006 -
present)
Lambiase, Louis R A 6 Week Novartis Study Of Females With GI Issues $ 2,905.00 Industry $ 20,937.50

Lambiase, Louis R Phase II Human Albumin-Interferon $ 3,000.00 Industry $ 97,563.78

Lambiase, Louis R IDEAL treatment for Hep C Geno 1 treatment naive $ 53,398.00 Industry $ 62,918.00

Lambiase, Louis R Short Term Treatment for chronic OBD $ 2,972.80 Industry $ 3,972.80

Lambiase, Louis R Long Term Treatment for Chronic OBD $ 1,000.00 Industry $ 2,000.00

Lambiase, Louis R Extension Protocol to Evaluate Long-Term Effects PEG-IF $ 2,700.00 Industry $ 3,400.00

Lambiase, Louis R Short Term Alizyme Renzapride Study in IBS-c (038) $ 26,117.00 Industry $ 30,587.00

Lambiase, Louis R ATL1251/052 Long Term Alizyme Study in IBS-c (052) $4,189.00 Industry $ 4,189.00

Lambiase, Louis R NV18209 Pegasys/Copegus in Hep C Co-Infected with HIV $ 7,809.50 Industry $16,303.25

Lambiase, Louis R HGS1008-C1060 Albumin Interferon compared to Pegasys $ 3,607.06 Industry $ 3,607.06

Munoz, Juan C C-Difficile Associated GI Treatments $ 9,717.00 Industry $ 20,933.67

Munoz, Juan C Tegaserod for the treatment of OIC with non-cancer pain $ 3,100.00 Industry $ 3,100.00

Vega, Kenneth J Comparison Of Normal Values Of Esophageal 24-Hour Acid $ 22,222.23 Industry $67,543.12

Vega, Kenneth J Validation of the GERQ for use in African Americans $ 16,041.67 Industry $16,041.67

Grants Awarded, not yet funded:


COPD patients diagnosed with gastro esophageal reflux disease have decreased rates of COPD
exacerbations after treatment with high dose proton pump inhibitor therapy.

Principal investigator: Kenneth Vega
Funding organization: TAP Pharmaceuticals
Starting date: June 2007
Award amount: $125,000


Gastroenteroloov


Division Chief: Louis Lambiase. MD


Annual Report AY 2007


Gastroenterology








DIVISION OF GENERAL INTERNAL MEDICINE
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Division continues a robust inpatient and outpatient practice and is an integral part of the
educational experience for the Internal Medicine residency.

Patient Care: The Division of General Internal Medicine is comprised of 14 members who are board
certified in Internal Medicine. Their clinical care includes: the provision of inpatient care as the
attending for the four inpatient teaching services, outpatient care at three locations: the ACC, Faculty
Clinic and the UF Multispecialty Clinic on Emerson, an inpatient Internal Medicine consultation service
and medical evaluation of patients admitted to the Psychiatry service. The Division has experienced
significant growth in its outpatient practice as the newer physicians in the group have established
themselves as excellent clinicians. One of the highlights of the outpatient practice is the JaxHATS
(Jacksonville Health and Transition Services) Clinics held on Tuesday and Thursday mornings. Dr.
Edwards, in conjunction with Dr. Wood, a general pediatrician, have established this new clinic that
provides a medical home for adolescents and young adults with special health care needs who are
transitioning from their pediatricians to adult providers. Dr. Foster has assisted

In the fall of 2006, Dr. House was appointed Chief, Division of Hospital Medicine.

Education: The Division provides faculty supervision of residents on the four general internal medicine
inpatient teaching services, inpatient medicine consultation service and geriatrics. The Division also
provides faculty supervision and mentoring of all categorical medicine residents in their outpatient
continuity practice and urgent care clinics.

Dr. Sottile conducted her second faculty development seminar for six members of the division in the fall
of 2006. The seminar ran for 8 weeks for a total of 16 hours. The topic was "Clinical Teaching". The
first seminar was held in the spring of 2006 with 8 faculty members participating. Dr. Sottile participated
as a facilitator in a faculty development seminar at Duke University. Dr. Sottile also serves as a facilitator
and is the co-developer of the "Teaching Residents to Teach"-a 6-8 hour intradepartmental seminar
offered each year at the University of Florida Health Science Center/Jacksonville.

Drs. Arpitha Ketty and Olga Petrucelli are Associate Program Directors for the Internal Medicine
residency program. Drs. Alexandraki and Palacio serve as Associate Clerkship Director and Clerkship
Director for medical students from Gainesville who rotate on the Internal Medicine service (inpatient and
outpatient). Dr. Jeff House coordinates monthly M&M/QA for the training program. Drs. House and
Alexandraki also serve as key clinical faculty for the Core Training Program in Internal Medicine.

Drs. Edwards, House, Ketty, Petrucelli and Sottile serve on the House Staff Evaluation Committee. Drs.
Alexandraki, Edwards, House, Ketty and Petrucelli also serve on the Resident Education Committee. All
members of the division have participated in and/or presented at the noon conference core curriculum
series held daily as well as the Friday afternoon ambulatory didactic sessions and Board review.

Research: Research in the Division continues to focus on continuing medical education, clinical
research, and faculty facilitation of resident research projects. Drs. House, Ketty and Petrucelli worked
with resident recipients of the Dean's Fund research awards. Dr. Halperin continues to focus on non-
traditional areas of research and has completed a study looking at the use of mind body medicine to


Annual Report AY 2007 General Internal Medicine


General Internal Medicine


Division Chief: Linda Edwards, MD









reduce stress in IM and ER residents. Dr. House has several clinical studies ongoing and Drs.
Alexandraki and Palacio are evaluating the Diabetes Education program at UF and Shands.



LISTING OF FACULTY MEMBERS

Current Faculty

Irene Alexandraki, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Athens, Greece
Hahnemann University Hospital
Baylor College of Medicine (Infectious Disease)


Linda Edwards, M.D., Associate Professor and Division Chief


Medical School / Graduation date
Internship/residency and year


East Carolina University
Jacksonville Health Education Programs


Malcolm Foster, M.D., Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Bowman Gray School of Medicine
University of Florida, Gainesville
University of Florida, Gainesville (Infectious Disease)


Alan Halperin, M.D., Professor

Medical School / Graduation date University of Kansas
Internship/residency and year University of Wisconsin

Jeffrey House, D.O., Assistant Professor

Medical School / Graduation date Nova Southeastern College of Osteopathic Medicine
Internship/residency and year University of Florida Jacksonville
Chief Medical Resident University of Florida Jacksonville

Arpitha Ketty, M.D., Assistant Professor

Medical School / Graduation date University of Southern California, Los Angeles
Internship/residency and year University of California, Davis

Ghania Masri, M.D., Assistant Professor


Medical School / Graduation date
Internship and year
Residency and year


Damascus University, Syria
Cleveland Clinic Foundation
Case Western Reserve University


Senthil Meenrajan, M.D. M.B.A, Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year
Post-graduate training and year


Madras Medical College, India
Robert Packer Hospital
Oregon Health Sciences University (Geriatric Medicine)
Canyon College (MBA: Healthcare Administration)


Carlos Palacio, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Post-graduate training and year


University of Miami
University of Florida, Jacksonville
University of North Florida (MBA: Healthcare Administration)


General Internal Medicine


1989
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1981
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1963
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1967



1971
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1997
2001
2001



1999
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1989
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1997
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2005
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1993
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2007


General Internal Medicine


Division Chief: Linda Edwards. MD


Annual Report AY 2007









Olga Petrucelli, M.D., Assistant Professor

Medical School / Graduation date University of South Florida 1996
Internship/residency and year University of Chicago Hospital 1999

James Phillips, M.D., Assistant Professor

Medical School / Graduation date St. George's University, West Indies 2001
Internship/residency and year University of Florida, Jacksonville 2005

Pramod Reddy, M.D., Assistant Professor

Medical School / Graduation date Sri Dev Raj Urs Medical College, India 1992
Internship/residency and year Stony Brook University Hospital 2000

Manish Relan, M.D., Assistant Professor

Medical School / Graduation date Armed Forces Medical College, India 1995
Internship and year Brookdale University Hospital 2000
Residency and year Scranton Temple Residency Program 2002

Elisa Sottile, M.D., Assistant Professor

Medical School / Graduation date Temple University School of Medicine 1993
Internship/residency and year University of Pennsylvania 1997



PUBLICATIONS

I. Alexandraki, Contributing author "Community Acquired Pneumonia" chapter of the textbook "Medicine
Essentials for Clerkship Students", Clerkship Directors in Internal Medicine-ACP, 2006

I. Alexandraki, Contributing author "Urinary Tract Infection" chapter of the textbook "Medicine Essentials for
Clerkship Students", Clerkship Directors in Internal Medicine-ACP, 2006

Collet-Sicard Syndrome: An Uncommon Manifestation of Metastatic Prostate Cancer: G. Chacon,
I. Alexandraki, C. Palacio. Southern Medical Journal2006 Aug; 99(8):898-9

Natural history of Vascular Access Catheters in Hemodialysis Patients, V. Lopez de Mendoza, S Reddy,
R Sullivan, C Le, N Naik, R Zaiden, I Alexandraki, B Cuhaci, NS Nahman Jr., Accepted, Southern AFMR, J Invest
Med, in press

Hepatitis C Viral Load and the risk of Bacteremia in Hemodialysis patients with Vascular Catheters,
S Reddy, R Zaiden, R Sullivan, N Niak, I Alexandraki, NS Nahman Jr., Accepted, Southern AFMR, J Invest Med, in
press

Surveillance cultures in Hemodialysis patients with vascular catheters, R Sullivan, R Zaiden, S Reddy,
V Lopez, H Kim, I Alexandraki and N S Nahman Jr. Abstract F-554028 presented at ASN 39th Annual Renal Week
Meeting, San Diego, CA, 2006

Cross-sectional study of the relationship between hepatitis C and bacteremia in hemodialysis patients with vascular
catheters, R Zaiden, R Sullivan, S Reddy, V Lopez, H Kim, I Alexandraki, and N S Nahman Jr., Abstract F-554111
presented at ASN 39th Annual Renal Week Meeting, San Diego, CA, 2006

Relationship between Hepatitis C and Bacteremia in Hemodialysis Patients with Catheters, R. Sullivan,


Annual Report AY 2007 General Internal Medicine


General Internal Medicine


Division Chief: Linda Edwards, MD






General Internal Medicine Division Chief: Linda Edwards, MD

R. Zaiden, D. Jones, I. Alexandraki, U. Bhatt, H. Vu, NS. Nahman Jr. Abstract presented (oral presentation) in the
2006 Meeting of the Southern Society for Clinical Investigation, Atlanta, GA.
JInvestMed, 54:S298, 2006

Halperin AK, Rathore M. Laughter therapy improves depression in patients with HIV/AIDS. (in preparation).

Arnaldo, F, House 3, Cocaine-induced non- ST elevation myocardial infarction: an uncommon electrocardiographic
presentation. Emergency Medicine Journal 2006; 23;816-817

Mediastinal Pancreatic Pseudocyst A Case Report and Review of the Literature. Ruchi Gupta,MD; Juan C.
Munoz,MD; Praveen Garg,MD; Ghania Masri MD; Norris S.Nahman;MD; Louis R. Lamdiase,MD. Medscape
General Medicine. 2007; 9(2):8.

The Role of Clinical Information Systems in Healthcare Quality Improvement
The Health Care Manager 25(3), 206-12 July 2006.
Harrison, Jeffrey P. and Palacio, Carlos
PMID: 16905990

Collet-Sicard Syndrome: An Uncommon Manifestation of Metastatic Prostate Cancer
Gina Chacon, MD, Irene Alexandraki, MD, Carlos Palacio, MD
Case Report
South Med J. 2006 Aug; 99(8):898-9
PMID: 16929891

A Conceptual Model for Benchmarkinq Electronic Medical Records Initiatives
Palacio, C, Harrison, JP, Garets, D
Journal of Healthcare Information Management (submitted August 2007)
37
Characteristics of Patients Prescribed Anciotensin Converting Enzyme Inhibitors, Anciotensin Receptor Blockers, or
the Combination at an Urban Medical Center Masri, Ghania MD; Bledsoe, Kristi PharmD; Palacio, Carlos MD
(Submitted MedGenMed June 2007)

Palacio C. Rickets. BMJ Publishing Group Point-of-Care Web site. 2007, Pending Publication

Palacio, C. Contributing author "COPD" chapter of the textbook "Internal Medicine Essentials for Clerkship
Students" 4th edition, ACP- Clerkship Directors in Internal Medicine, 2008 (in preparation)

Palacio, C. Contributing author "Hepatitis" chapter of the textbook "Internal Medicine Essentials for Clerkship
Students" 4th edition, ACP- Clerkship Directors in Internal Medicine, 2008 (in preparation)
Palacio, C. Writer Multiple Choice Question for CDIM MKSAP 4 for students (hepatitis and COPD)

Palacio, C. Reviewer MKSAP for Students 4 Multiple Choice Questions (Endocrinology and General Medicine)

E Ibegbu, Relan, M, Vega, K. American Journal of Gastroenterology, Retrograde Jejunoduodenogastric
Intussusception Caused by a Migrated Percutaneous Feeding Tube: Case report and Review of the Literature,
Publication Date: 2006, Pending Publication.


HONORS AND AWARDS

Irene Alexandraki, M.D. Fellowship, American College of Physicians

Linda Edwards, M.D. Elected Member and Vice-President, Faculty Council HSC/Jacksonville
Member, Executive Committee, UF Self-Insurance Program

Annual Report AY 2007 ,, General Internal Medicine







General Internal Medicine Division Chief: Linda Edwards. MD


Malcolm Foster, M.D.






Alan Halperin, M.D.

Jeff House, D.O.


Carlos Palacio, M.D.






Manish Relan, M.D.


Governor, Florida Chapter of the American College of Physicians
Board of Directors, Duval County Medical Society
Board of Directors, ACP Foundation, Vice-Chairman
Chair, Pharmacy and Therapeutics Committee UF & Shands
Jacksonville Medical Center (SJMC)

Chair, Institutional Review Board, UF & SJMC

University of Florida Exemplary Teacher Award 2006
Fellow, American College of Physicians

Vice-Chair, Institutional Review Board
University of Florida Exemplary Teacher Award 2007
Fellowship, American College of Physicians
MPH, University of North Florida August 2007
Elected Member, Faculty Council

University of Florida Exemplary Teacher Award 2007


CLINICAL ACTIVITIES

Inpatient Activity AY 06/07
Numbers of Inpatient Admissions 4330
Inpatient Days 22892
Average length of stay 5.29
Number of OBU Admissions 1459
Number of SNU Admissions 314
Number of IP Consults 1910

Outpatient Activity
Clinic Visits 17696


General Internal Medicine


General Internal Medicine


Division Chief: Linda Edwards. MD


Annual Report AY 2007

























































































42








DIVISION OF HEMATOLOGY & MEDICAL ONCOLOGY
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Division's move of administrative office space to the 4th floor of the Pavilion Annex in November
2005 has been a success for the Medical Oncology Division. In 2006 the division hired an outpatient
social worker to improve patient care. Medical oncology was provided resources to develop a call center
that would improve access to patient care. Communication among all patient care related staff has
increased as a result of centralization of most oncology services. The division continues to expand multi-
disciplinary clinics and with the addition of the Thoracic Oncology Multi-Disciplinary Clinic there has been
a significant improvement in patient convenience.

Patient care: The division continues to work closely with hematology-oncology leadership, and central
administration of the UF College of Medicine Gainesville, to coordinate the divisional mission with
growth and development of the Proton Beam Treatment Facility. It is anticipated that when at full
capacity, the facility will result in a 30-50% increase in inpatient and outpatient activity. With hiring of
additional faculty, the division has increased its ability to serve patient demands and to set a foundation
for increasing patient volumes.

Education: The division continues to support the Internal Medicine Residency Program through
facilitation of morning report and noon conference core curriculum. The division offers a consult
experience in medical oncology to residents of all training levels. We have a weekly didactic lecture
series that gives fellows the opportunity to present cases to faculty. Continuing support of education to
division fellows, we have a monthly Journal Club that generates discussion on various oncology related
topics throughout the year. The fellowship in medical oncology continues to prosper with all positions for
July 2006 and 2007 filled.

Research: The Division is currently engaged in 15 clinical hematology/oncology trials. With the
opening of the new clinical facilities and the addition of faculty, new clinical research initiatives began in
hematology.

Recruitment efforts led to the arrival of Dr. Fauzia Rana in June 2006, along with Dr. Ru-Amir Walker in
July 2006. We have been successful with hiring of Dr. Janet Hosenpud. Her arrival is expected in July of
2007, and she will be the new Fellowship Director. With these recruitment initiatives, the expanded
clinical infrastructure and continued development of the Proton Beam Treatment Facility, the division
expects to continue expanding all facets of the academic mission.


LISTING OF FACULTY MEMBERS

New Faculty

Fauzia Rana, MD, Assistant Professor

Medical School / Graduation date Fatima Jinnah Medical College 1982
Internship/residency and year University of Rochester New York 1990
Subspecialty training and year Dana Farber Deaconess Hospital/Harvard 1993

Ru-Amir Walker, MD, Assistant Professor
Medical School / Graduation date St George University 2001
Internship/residency and year University of Florida Jacksonville 2004
Annual Report AY 2007 Hematology/Oncology


Hematoloov/Oncoloav


Division Chief: James Chingos, MD







Heaola/ncla Diiso Che:Jms hno.M


Subspecialty training and year


University of Florida Jacksonville


2006


Current Faculty


James Chingos, MD Associate Professor and Chief


Medical School / Graduation date
Internship/residency and year

Subspecialty training and year


Albany Medical College
Tufts New England Medical Center
Memorial Sloan Kettering Cancer Center
Tufts New England Medical Center


Dat Pham, MD Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Florida Jacksonville
University of Florida Jacksonville
University of Florida Jacksonville


1973
1975
1976
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1997
2000
2002


PUBLICATIONS

"Lung Cancer Screening: Past, Present and Future," Ru-Amir Walker, M.D.



HONORS AND AWARDS

President, Association of Community Cancer Centers, 2006-2007 James Chingos M.D.
ACOS Commission on Cancer Accreditation 3 Year Approval (2007)
AMA Physician Recognition Award 3 Year Approval 2006 James Chingos, M.D.



CLINICAL ACTIVITIES


Inpatient Activity AY 06/07
Numbers of Inpatient Admissions 363
Inpatient Days 2759
Average length of stay 7.60
Number of OBU Admissions 11
Number of IP Consults 471

Outpatient Activity
Clinic Visits 6361


CONTRACTS AND GRANTS


Principal Sponsor Title
Investigator

Pham, Dat Amgen, Inc. Phase III Trial, Bones Mets Advanced Cancer (Excluding Breast and Prostate Cancer) or Multiple
Myeloma

Pham, Dat 13 Research Phase III Trial, Breakthrough Cancer Pain in Subjects taking opoids

Pham, Dat 13 Research Phase III Trial, Breakthrough Cancer Pain in Subjects taking opoids long term

Pham, Dat Favrille Phase II Study of Continued Immunotherapy with FavId (Id-KLH) and GM-CSF in Patients with Stable


Hematoloov/Oncoloav


Division Chief: James Chinoos. MD


Annual Report AY 2007


Hematology/Oncology










or Responding Grade 1 or 2 Follicular B-Cell Lymphomas

Pham, Dat Medarex Phase III Trial, Melanoma Stage III or IV

Pham, Dat Sanofi-Synthelabo Hyperuricemia Plasma Uric Acid Management

Pham, Dat Merck & Co, Inc. Phase I/II, Lung NCSLC Relapses or Refractory

Walker, Ru-Amir Amgen, Inc. Phase II, MDS Indication Thrombocytopenia associated with lenalidomide therapy in MDS

Walker, Ru-Amir Amgen, Inc. Phase II, MDS Indication Thrombocytopenia associated with hypomethylating agent therapy in
MDS

Chingos, James Icagen Inc. Phase III Trial, Sickle Cell Acute Pain

Chingos, James Icagen, Inc. Phase III Trial, Sickle Cell Acute Pain, Long Term Extension Study

Chingos, James Bristol-Myers Phase III Trial, CML with Chronic Philadelphia Chromosome Positive
Squibb
Rana, Fauzia Alexion Examination of PNH, by Level of CD 59 pm RBC and WBC in bone marrow failure syndrome


Annual Report AY 2007 Hematology/Oncology


Hematoloov/Oncoloav


Division Chief: James Chingos, MD


Annual Report AY 2007


Hematology/Oncology

























































































46








DIVISION OF HOSPITAL MEDICINE
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Division of Hospital Medicine has experienced a vast amount of growth and maturity considering the
program is still in its infancy. For the fiscal year of 2007, which surpassed expectations set in 2006, the
hospital medicine program continues to exceed the efficiency demands of complex patient care. Dr. Jeff
House continues to serve as Associate Professor and Chief of the Hospitalist Program. The program is
mainly structured to serve acute or general inpatient care. However, the Division also provides initial
hospital care to emergency and observation room patients to expedite the admission process and to
prevent unnecessary admissions. Clinically, the most important event includes allocating most of the
inpatient care at the Pavilion. In research, we have acquired a dual Hospitalist and Researcher.
Academically, the Division as a whole has not been able to participate in any abstracts or presentations
due to our limitation as a non academic division.

Patient Care: The Division of Hospital Medicine provides care for one quarter or 25% of all inpatient
admissions as a result of attrition of other private practice physicians, dissolution of family medicine
residency and hospital bed expansion. In addition to caring for medical inpatients, the Hospitalists also
perform consultations on other services. The end result of these changes has led to in an increase in the
average daily census from roughly 100 for Fiscal Year 2006 to 130 in Fiscal Year 2007. This number
continues to rise with the addition of patients from the Pavilion. This Division routinely cares for the
more hospitalized patients of any other service and provides continuous care to the city's indigent,
uninsured and underinsured. The Hospital Medicine Physicians also provide care for Humana Medicare
patients, University of Florida satellite offices and overflow patients from the teaching services. On
several occasions, the Hospitalists provide assistance to Cardiology when its services are maxed. The
Division of Hospital Medicine provides in house 24 hour care which is vital to providing quality health
care for nightly admissions and cross cover issues.

For the Academic Year of 2007, the Division of Hospital Medicine established a State of the Union
Hospitalist Committee. Its primary responsibility is to ensure that patient quality and safety is embedded
in the culture of our program. This year has also marked the increasing scope of care Hospitalist service
provides.

Education: Although not directly involved with the educational mission of the internal medicine
residency, the hospital medicine program played a critical role. Hospital Medicine service continues to be
the buffer that allows the Internal Medicine residency to comply with Residency Review Committee rules
regarding patient care and duty hours. The hospital medicine staff is also responsible for monitoring
procedures performed by residents at night.

Dr. House has been intimately involved in the residency program. He is also a member of the internal
medicine faculty; he serves in many facets of resident education. These duties include attending resident
continuity clinic and ward services as well lecturing at core conferences and morning report. He also
participates in night float rounds on a regular basis. In addition, Dr. House is the director of Clinical
Quality Improvement for the residency program. Along with these duties, his position also entails that
he proctors the monthly Morbidity and Mortality Conference. Finally, Dr. House is also a member of the
Resident Education committee and Key Clinical Faculty.

In the upcoming year, the division has devised plans to expand their educational role by initiating an
elective rotation beginning in July 2007. Goals and Objectives for this rotation have been established
Annual Report AY 2007 Hospital Medicine


HosPital Medicine


Division Chief: Jeff House. DO









and completed ahead of the target date. The hospital medicine division also participates in a monthly
journal club presentation and attends the monthly Morbidity and Mortality conference.

Research: Since the Division of Hospital Medicine is primarily focused on the inpatient care service, this
has not been an area of emphasis for the division. The division is participating in the Joint Commission
of Accredited Healthcare Organizations (JCAHO) core measures surrounding community acquired
pneumonia and congestive heart failure. There are 2 faculty (Drs Garg and House) who are currently
members of the Medical Performance Improvement Committee. Dr. Garg is the Physician Champion for
community acquired pneumonia. For the academic year of 2007, the division of hospital medicine
acquired Dr. Kancha, M.D., Ph.D, (Drexel University and George Washington University), who has
initiated research on various focuses such as Male Hormone Replacement Therapy and Molecular
Mechanisms of Lipoprotein Receptor Gene Regulation.


LISTING OF FACULTY MEMBERS

New Faculty

Ravi Kancha, M.D. Ph.D., Assistant Professor

Medical School / Graduation date Ross University Medical School 2002
Internship/residency and year Drexel University College of Medicine 2004
Internship/residency and year George Washington University Hospital 2007
Postgraduate training and year Osmania University (PhD Biochemistry) 1991

Vijay Konda, M.D., Assistant Professor

Medical School / Graduation date Gandhi Medical College, India 2000
Internship/residency and year Weiss Memorial Hospital 2006

Current Faculty

Angelika Kharrazi, M.D., Assistant Professor

Medical School / Graduation date Saba University School of Medicine, Netherlands 2000
Internship/residency and year University of Florida, Jacksonville 2006

Ernst Michel, M.D., Assistant Professor

Medical School / Graduation date University of Montemorelos, Mexico 2001
Internship/residency and year San Juan City Hospital, Puerto Rico 2006

Nonette Asistores, M.D., Assistant Professor

Medical School / Graduation date De La Sallee University, Philippines 1986
Internship/residency and year University of Florida, Jacksonville 2004

Praveen Garg, M.D., Assistant Professor

Medical School / Graduation date MBBS, University of Delhi, India 1998
Internship/residency and year University of Rochester 2006

Saw Po, M.D., Assistant Professor

Medical School / Graduation date Institute of Medicine II, Myanmar (Burma) 1987
Internship/residency and year University of Florida, Jacksonville 2001

Annual Report AY 2007 Hospital Medicine


Hospital Medicine


Division Chief: Jeff House. DO









Edgar Alvarez, M.D., Assistant Professor

Medical School / Graduation date National University of Columbia 1975
Internship/residency and year University of Florida, Jacksonville 1994

Arshia Cottey, M.D., Assistant Professor

Medical School / Graduation date Dow Medical College, Pakistan 1993
Internship/residency and year University of Florida, Jacksonville 2001

John Daniels, D.O., Assistant Professor

Medical School / Graduation date University of Health Sciences college of Osteopathic Medicine 2002
Internship/residency and year University of Florida, Jacksonville 2006

Ivan Rason Aguilar, M.D., Assistant Professor

Medical School / Graduation date Universidad San Carlos de Guatemala, Guatemala 2000
Internship/residency and year University of Florida, Jacksonville 2005

Monique Walcott, M.D., Assistant Professor

Medical School / Graduation date Boston University 2003
Internship/residency and year University of Florida, Jacksonville 2006

Jeff House, D.O., Associate Professor and Division Chief

Medical School / Graduation date Nova Southeastern University 1997
Internship/residency and year University of Florida, Jacksonville 2001



PUBLICATIONS

Arnaldo F, House 3, Cocaine-induced non- ST elevation myocardial infarction: an uncommon electrocardiographic
presentation. Emergency Medicine Journal 2006; 23;816-817

Garg P, Gupta R, Hsi D, Sheils L, DiSalle MR, Woodlock TJ. Hypertrophic cardiomyopathy and symptomatic
conduction system disease in Cardiac Amyloidosis. Southern MedicalJournal. 2006;99:1360-62

Garg P, Gupta R, Szalados J. Bacterial Pericarditis and Tamponade due to Non-Encapsulated Hemophilus
Influenzae Complicating an Adult Community Acquired Pneumonia. MedGenMed 2006 Dec 7; 8(4):8

IE Rascon-Aguilar, M Pamer, NS Nahman Jr, KJ Vega: Role of gastroesophageal reflux symptoms in
exacerbations of COPD. Chest2006 Oct;130(4):1096-101


HONORS AND AWARDS

Jeff House, MD Exemplary Teacher Award 2006








Annual Report AY 2007 Hospital Medicine


Hospital Medicine


Division Chief: Jeff House. DO







oIt n


CLINICAL ACTIVITIES


Inpatient Activity
Numbers of Inpatient Admissions
Inpatient Days
Average length of stay
Number of OBU Admissions


Annual Report AY 2007 Hospital Medicine


AY 06/07
4436
26724
6.02
1580


Hospital Medicine


Division Chief: Jeff House. DO


Annual Report AY 2007


Hospital Medicine








DIVISION OF INFECTIOUS DISEASES
ACADEMIC YEAR 2007 (7/06-06/07)

Highlights

The Division of Infectious Diseases continued its clinical and academic missions. A full staffing
complement without loss was maintained. The division is currently comprised of 7 infectious diseases
consultants (5 of whom are dually boarded in internal medicine and infectious diseases; 2 are boarded in
internal medicine, eligible in infectious diseases, have taken the infectious diseases certifying boards); 1
Nurse research coordinator, and 1 travel medicine nurse. The division provides clinical consultation in
infectious diseases at Shands Jacksonville Medical Center SJMC), hospital infection control direction and
transplantation infectious diseases consultation at SJMC, outpatient travel and tropical medicine services,
outpatient infectious diseases consultation, and clinical infectious diseases research. The division
maintains an ACGME accredited infectious diseases fellowship training program and actively participates
in training internal medicine residents and medical students in inpatient and outpatient infectious
diseases. The division has a contract with the Duval County Health Department (DCHD) to provide
professional consultation and programmatic direction for HIV/AIDS, TB and STD programs and clinical
care to the counties' HIV/AIDS, TB and STD patients in the DCHD specialty clinics. The contract funds
5.2 FTE of the 7 FTE of division's ID physician time.

Each member of the division has a strong administrative role in division activities. Dr. Sands is currently
the University ID Division Chief, Director of Communicable Diseases for Duval County Health
Department, and ID Division Fellowship Program Director. Dr. Vandevelde chairs and directs hospital
infection control for SJMC, directs the travel medicine section and is Assistant Program Director for the
ID division fellowship program. Dr. Toomey is Director of the STD section and coordinates resident and
student education. Dr. Mitchell-Samon is Director of the HIV section. Dr. Bailey is Director of the
refugee health section and infections in transplantation consultative liason. Dr. Lauer is Chief of the TB
section.

Patient Care: The division provides full time infectious diseases consultation throughout the Shands
Jacksonville Medical Center system. Between July and November 2006; 293 inpatient clinical
consultations were provided and subsequently followed at SJMC. During the 2005-2006 academic year
the division performed over 750 inpatient infectious diseases consultations with subsequent follow-up at
SJMC.

The division offers outpatient ID consultation by referral at its clinics. Travel medicine services are
provided daily for overseas travelers. 483 travel patient visits have been seen between July 1, 2006 and
November 30, 2006.

The division provides professional and administrative oversight and care for HIV/AIDS, TB, STD and
refugee screening clinical services for DCHD specialty clinics. In the 4 month period July 1 October 31,
2006, ID division physicians delivered or over-sighted care for 3,546 HIV/AIDS clinical visits, 1,214 STD
visits, 141 refugee visits, and 653 TB visits at DCHD specialty clinics.

Education: Dr. Sands is Editor of the biweekly DCHD Epidemiology Report electronically circulated
throughout Duval County and the state. The division actively participates presenting at Medical Grand
Rounds and are regular attendees. The division maintains an ACGME accredited fellowship in infectious
diseases with one fellow for each of the 2 clinical fellowship years.

Resident training:

Annual Report AY 2007 Infectious Disease


Infectious Diseases


Division Chief: Michael Sands, MD








Resident morning report attendees
ID noon core curriculum conferences
ID consultation teaching rounds
Outpatient HIV/AIDS continuity clinics
Resident ID Board review sessions

Medical student education:
Dr. Toomey HIV/AIDS core content conference by teleconference with UF College of
Medicine Gainesville.
Medical student rotations on the infectious diseases consultative service

ID division conference schedule:
The division maintains a full conferencing schedule with ongoing meetings Monday and Thursday noon.
Conference topics include:
regularly scheduled cases conferences
ID Board reviews
Journal Club
HIV topical reviews
TB cases and topical reviews
Research conferences
Travel and tropical medicine conferences
Transplantation ID conferences
Med Peds ID joint conference each month.

Dr. Sands attended the "Faculty as Teachers" workshop offered through UF.

Research: Drs. Guzman and Bailey serve as members of the University of Florida/Jacksonville
Institutional review board. Dr. Sands is the PI for the division's NIH sponsored CPCRA HIV clinical trials
program. The division is responsible for performance of components of federal and state categorical
grants awarded to the DCHD for TB, HIV, refugee and STD care and epidemiologic services. These
grants are in excess of $6.5 million. Additionally the division has been instrumental in acquiring and
directing a federal Ryan White Title 3 grant of $300,000 annually for improved community based access
to care, that provides HIV/AIDS care to 250 indigent patients not otherwise brought into care or
previously lost from care.


LISTING OF FACULTY MEMBERS

Michael Sands, M.D., MPH & TM, Associate Professor and Division Chief

Medical School / Graduation date Georgetown University 1972
Internship/residency and year St. Mary's Hospital 1974
Subspecialty training and year Louisiana State University (Infectious Disease) 1977
Subspecialty training and year Northwestern Memorial Hospital (Clinical Microbiology) 1981
Post-graduate training Tulane University of Public Health (MPH&TM) 1975

Alexander Vandevelde, M.D., Associate Professor

Medical School / Graduation date University of Louvain, Belgium 1963
Internship/residency and year Jacksonville Health Education Program 1969
Subspecialty training and year University of Florida, Gainesville 1971


Annual Report AY 2007 Infectious Disease


Infectious Diseases


Division Chief: Michael Sands, MD







Infectious Diseases Division Chief: Michael Sands. MD


James Toomey, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Northwestern University
University of Florida, Jacksonville
University of Florida, Jacksonville


Christina Bailey, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of Texas, Houston
University of Florida, Jacksonville
University of Florida, Jacksonville


Levonne Mitchell-Samon, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of South Florida
University of Florida, Jacksonville
University of Florida, Jacksonville


Jeffrey Lauer, M.D., Clinical Instructor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


University of New Mexico
University of Florida, Jacksonville
University of Florida, Jacksonville


Nilmarie Guzman, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Ponce School of Medicine, Puerto Rico
Dumas Hospital, Puerto Rico
University of Florida, Jacksonville


PUBLICATIONS


Crossman A, Mendez 3, Vandevelde A, Sands M. Spontaneous bacterial
enteritidis. Infect Med 2006;23:286-288.

EI-Sadr W and the SMART study group including Sands M. CD4
interruptions: Results of the SMART study. NEng J Med 2006;355:2283-96..


empyema caused by Salmonella


Guided Antiretroviral treatment


Kay R, Vandevelde A, Fiorella P, Crouse R, Blackmore C, Sanderson R, Bailey C and Sands M. An
outbreak of healthcare associated multidrug resistant Salmonella Seftenberg in Florida. Inf Control Hosp Epi
accepted for publication.

Guzman N, Sands M. The expanding spectrum of neurologic complications of HTLV1. submitted Infectious
Diseases in Clinical Practice

Dr. Sands is the editor of the biweekly DCHD epidemiology report electronically circulated throughout Duval county
and the state.

Hepatitis B vaccination experience in a large inner city HIV clinic C. Bailey

Tigecycline plus polymyxin synergy in vitro against multiresistant Acinetobacter sp. Sands M, Sanchez W,
McCarter Y.

Should Terbinafine be considered in the therapy of systemic fungal infections Guzman N, Sands M.


Annual Report AY 2007


1982
1991
1994



1995
1998
2000



1997
2000
2002



1994
1997
1999


1996
1999
2006


Infectious Diseases


Division Chief: Michael Sands, MD


Infectious Disease








Infectious Diseases Division Chief: Michael Sands. MD


CLINICAL ACTIVITIES


Inpatient Activity AY 06/07
Number of IP Consults 625

Outpatient Activity
Clinic Visits 98


CLINICAL TRIALS AND GRANTS

Dr. Sands is the PI for the division's NIH sponsored CPCRA HIV clinical trials program.

Multiple corporate sponsored clinical trials are currently being conducted in the division under the clinical trials program. Dr.
Sands is the PI on the majority of these trials. All division members are active in the trials as co-investigators

Principal Sponsor/Title
Investigator

Sands, Michael AI424128 A Phase IV, Multi-center, cross-sectional study to evaluate the I50L Substitution Among Subjects Experiencing
Virologic Failure on HAART Regimen containing Atazanavir

Sands, Michael NV17751 Observational Cohort Study of Pneumonia in Fuzeon-Exposed and Non-Exposed Patients

Sands, Michael CPCRA 065 A Large, Simple Trial Comparing Two Strategies for Management of Anti-Retroviral Therapy (the SMART Study)

Sands, Michael CPCRA 065F Neurology: A Substudy of a Large, Simple Trial Comparing Two Strategies of Anti-Retroviral Therapy to
Determine the Impact of the Strategies upon Central and Peripheral Nervous System Function.

Sands, Michael CPCRA 065G Anal Dypsplasia: A Substudy of a Large Simple Trial Comparing Two Strategies for Management of Anti-
Retroviral Therapy

Sands, Michael CPCRA 065H Genomics: A Substudy of a Large, Simple Trial Comparing Two Strategies for Management of Anti-Retroviral
Therapy

Sands, Michael Ceftibuten Study: Evaluation of Single-Dose Ceftibuten for Treatment of Uncomplicated Gonococcal Urethritis in Men
(mentor)

Sands, Michael ABC107442 A retrospective case-control study to estimate the sensitivity and specificity of a pharmacogenetic marker (HLA-
B*5701) in subjects with and without hypersensitivity to abacavir

Guzman, TMC125 Early access of TMC125 in combination with other antiretrovirals in treatment-experienced HIV-1 infected subjects
Nilmarie with limited treatment options.

Bailey, Christina A prospective study of the effect of Compath use on renal transplant outcomes

Mitchell-Samon, An accelerated schedule for Hepatitis B vaccination of HIV patients Pilot study assessing completion rates and
Levonne seroconversion


Annual Report AY 2007


Infectious Diseases


Division Chief: Michael Sands, MD


Infectious Disease








DIVISION OF NEPHROLOGY AND HYPERTENSION
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

The Division of Nephrology and Hypertension had a year of rapid growth and development in all areas of
the academic mission. Dr. Nahman returned as Division Director after serving as Interim Chairman of
the Department of Medicine. The most significant advance was ACGME approval of the Nephrology
Fellowship Training Program which will begin in July 2007. Clinically, major events included remodeling
the inpatient acute dialysis unit, the planned opening of our first off-campus outpatient hemodialysis
center, and establishment of stable vascular access services. In research, the new research building
opened allowing nephrology laboratories to relocate to the facility, and the division initiated a
collaborative clinical data mining study with the University of North Florida. Academically, the division
presented abstracts at the ASN in San Diego, AFMR in New Orleans, and National Dialysis Conference in
San Francisco. The division succeeded in acquiring another NIH grant, several internal grants, and
collaborated with our dialysis partner (DCI) for support of the Fistula First Program.

Patient care: The most important advances this year were the remodeling of the inpatient acute
dialysis unit, construction of a new outpatient dialysis facility, and DCI support of vascular access
surgeon Dr. Bruce Sommer. Dr. Cuhaci joined the division as a critical care nephrologist and will bring
needed expertise in CRRT. The new inpatient acute dialysis unit is slated to open in fall 2007 and will
have 8 open hemodialysis stations, 1 isolation bed, full ICU monitoring, and a digital urinalysis station for
performing and recording all urinalyses. The unit will allow appropriate delivery of inpatient dialysis
therapies and serve as the major teaching platform for the Nephrology Fellowship Training Program. In
the outpatient arena, the Division of Nephrology will serve as Medical Director of a new 24 station
dialysis facility, which is expected to open in August 2007. With support from DCI, Dr. Sommer and the
division have established a weekly outpatient vascular access clinic and provision of appropriate surgical
access support.

Education: The most significant event this year was ACGME approval of the nephrology fellowship in
May. The program received a 2 year provisional accreditation, will begin in July 2007 with 2 fellows, and
will be under the direction of Dr. Nahman. In residency education, Dr. Maddirala joined the group as
Director of relevant educational programs for Nephrology, and as Associate Director of the fellowship.
She is the primary liaison between the Core Residency Program and the division, and is a member of the
Resident Education Committee.

Research: Opening of the new research building allowed relocation of the nephrology laboratories and
research offices to the facility. Basic science programs in the area of biomarkers in renal disease are
moving forward. A clinical research project with the United States Renal Data System (USRDS, an NIH
supported database of all end stage renal disease and transplant programs in the US) was a significant
advance for the clinical research mission. The project continues collaboration with data mining expert
Dr. Sherif Elfayoume at the University of North Florida and has produced an abstract submission to the
ASN. In other areas, Dr. Vu continued to serve as a Site Co-investigator in the Coral trial of renal artery
stenosis, Dr. Maddirala is collaborating with Infectious Diseases to establish an HIV nephropathy clinic
and Dr. Urquidi and colleagues received a second $1.2 million NIH grant to study diagnostic methods for
bladder cancer. Drs. Nahman and Cu presented abstracts at the ASN and Dr. Mars presented at the
Annual Dialysis Conference. Dr. Nahman sponsored 3 trainee presentations at the Southern AFMR and
mentored several residents in successful internal grant applications. Dr. Urquidi presented at the
International Proteomics meeting in Luxembourg, and at the annual meeting of the American Association
for Cancer Research.
Annual Report AY 2007 Nephrology


Neohroloov and Hvoertension


Division Chief: N. Stanlev Nahman. Jr. MD









In the past year, the division successfully recruited Dr. Bulent Cuhaci (Texas Tech) and Dr. Supriya
Maddirala (University of Oklahoma) and is currently recruiting Leorah Ross, M.D., Ph.D. (U Mass,
Worcester) as a second transplant nephrologist. Dr. Bhatt departed in September 2006. With the
substantial progress made in the past year, the division plans to see the above projects and initiatives
through to completion and use them as basis for building and maturing all facets of the academic
mission.



LISTING OF FACULTY MEMBERS

New Faculty

Bulent Cuhaci, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year
Subspecialty training and year


Istanbul Faculty of Medicine, Istanbul, Turkey
St Agnes Hospital, Baltimore, MD
Mount Sinai Hospital, NY (Critical Care Medicine)
Hahnemann University, Medical College of Pennsylvania (Nephrology)


Supriya Maddirala, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


American University of the Caribbean
University of Oklahoma
University of Oklahoma


Current Faculty

Gil Cu, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year
Post-doctoral training


University of the Philippines
Lutheran Medical Center, NY
Beth Israel Medical Center, NY
Rockefeller University


Ronald Mars, M.D., Associate Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


St Louis University
Emory University
Emory University


N. Stanley Nahman, Jr., M.D., Professor and Division Chief


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


Medical College of Ohio
Presbyterian Hospital Denver, Mt Carmel Health, Columbus
Ohio State University


Virginia Urquidi, Ph.D., Research Associate Professor


Graduate School and year
Ph.D.
Post-doctoral training


University of Bilbao, Spain
Oxford University, UK
Oxford University, UK


Hang Vu, M.D., Assistant Professor


Medical School / Graduation date
Internship/residency and year
Subspecialty training and year


UT San Antonio
Texas Tech University
UTMB Galveston


Annual Report AY 2007 Nephrology


1985
1995
1996
1998



2000
2003
2006


1983
1991
1995
1996



1972
1976
1978



1979
1984
1987



1978
1992
1994



1997
2000
2002


Neohroloov and Hvypertension


Division Chief: N. Stanley Nahman. Jr. MD


Annual Report AY 2007


Nephrology










PUBLICATIONS

Spetie DN, Nadasdy T, Nadasdy G, Agarwal G, Mauer M, Agarwal AK, Khabiri H, Nagaraga HN, Nahman Jr NS,
Hartman JA, Hebert LA: Proposed pathogenesis of idiopathic loin-pain hematuria syndrome. AmerJ Kidney Dis
47:419-427, 2006.

Rascon I, Pamer M, Vega K, Cury J, Nahman Jr NS. The role of gastroesophageal reflux in exacerbations of
chronic obstructive pulmonary disease. Chest, 130:1096-1101, 2006.

Urquidi V and Goodison S. Genomic Signatures of Breast Cancer Metastasis. Cytogenetic and Genome Research.
in press.

Kreunin P, Yoo C, Urquidi V, Lubman DM, Goodison S. Proteomic Profiling Identifies Breast Tumor Metastasis-
Associated Factors in an Isogenic Model Proteomics. 7:299-312, 2007.

Maddirala S, Pitha JV, Cowley BC, Haragsim L. End stage renal disease due to polyoma virus in a cardiac
transplant patient. Nature Clin Prac Nephrol, in press.

Dickey CA, Kamal A, Lundgren K, Klosak N, Bailey RM, Dunmore J, Ash P, Shoraka S, Zlatkovic J, Echman CB,
Patterson C, Dickson D, Hutton M, Burrows F, Nahman Jr NS, Petrucelli L. The high-affinity Hsp90-CHIP complex
recognizes and selectively degrades phosphorylated tau client proteins. J Clin Invest, 117: 648-658, 2007.

Kreunin P, Zhao J, Rosser C, Urquidi V, Lubman DM, Goodison S.. Bladder Cancer Associated Glycoprotein
Signatures Revealed by Urinary Proteomic Profiling. JProteome Res. 6:2631-2639, 2007

Sullivan R, Samuel V, Le C, Khan M, Alexandraki I, Cuhachi B, Nahman Jr NS: Hemodialysis vascular catheter-
related bacteremia. AmerJ MedicalSci, in press.


HONORS AND AWARDS


N. S. Nahman, Jr., M.D.

N. S. Nahman, Jr., M.D.


Southern Society for Clinical Research

MKSAP 14 content reviewer


CLINICAL ACTIVITIES


Inpatient activity AY 06/07
Inpatient Nephrology admissions 310
Consults 898
Acute dialysis runs 4174

Outpatient activity
UF Jax Nephrology clinic visits 2584
Outpatient dialysis visits 4517


* Encompassing the 6 month period from January 06 June 06 only. Inpatient nephrology began January 1, 2006.


Annual Report AY 2007 Nephrology


2006

2006


Neohroloov and Hvoertension


Division Chief: N. Staniev Nahman. Jr. MD


Annual Report AY 2007


Nephrology








I a e s a


GRANTS AND CONTRACTS


Annual Report AY 2007 Nephrology


Principal Sponsor/Title Project period Total direct costs Release time
Investigator

Vu H CORAL trial for renal artery stenosis 7/06 goal $7385 / pt 0%
completing study

Urquidi V NCI-NIH/ Identification and functional analysis of metastasis 9/04-8/09 $1,250,000 15 %
proteins

Urquidi V NCI-NIH/Towards a non-invasive molecular test for bladder cancer 9/07 8/12 $1,250,000 25%

Urquidi V Susan G Komen breast cancer Research Fdn/Isolation of monclonal 7/06 6/08 $250,000 10%
metastasis-inhibiting antibodies

Urquidi V University of Florida Dean's Fund Faculty Research Grant/ The role 8/05 9/07 $10,000 0 %
of MMP8 protein isoforms in migration and invasion capabilities of
breast cancer cells

Sommer B, Fistula first program/Dialysis Clinic Inc 3/07 2/10 $225,000 100%
Nahman Jr NS (B Sommer)
(Co-PI)

Alexandraki I, University of Florida Dean's Fund Faculty Research 7/05 10/06 $5,000 0 %
Nahman Jr NS Grant/Hemodialysis vascular catheter-related bacteremia
(mentor)

Sullivan R, University of Florida Dean's Fund Resident Research Grant/ Risk 11/05 10/06 $5,000 0 %
Nahman Jr NS factors for gram negative bacteremia and central venous dialysis
(mentor) access

Zaiden R, University of Florida Dean's Fund Resident Research Grant/ Effect of 3/06 2/07 $5,000 0 %
Nahman Jr NS hepatitis C infection on cellular immunity in hemodialysis patients
(mentor)

Lopez V, University of Florida Dean's Fund Resident Research Grant/ 8/06 7/07 $2,000 0 %
Nahman Jr NS Changes in hemodialysis blood circuit parameters as predictors of
(mentor) catheter loss in dialysis patients

Reddy S, University of Florida Dean's Fund Resident Research Grant/ Effect of 8/06 7/07 $5,000 0 %
Nahman Jr NS hepatitis C viral load on bacteremic events in hemodialysis patients
(mentor)


Neohroloov and Hvoertension


Division Chief: N. Staniev Nahman. Jr. MD


Annual Report AY 2007


Nephrology








DIVISION OF PULMONARY & CRITICAL CARE
ACADEMIC YEAR 2007 (7/06 6/07)

Highlights

Patient Care: There were no significant changes in patient care duties. The Pulmonary Consult
Service, MICU, Thoracic Oncology Program, and Sleep Center continued to grow. Clinic volume
decreased as there was a decrease in manpower within the division. The Pavilion MICU move into the
Clinical Center and continued departure of community physicians led to the large increase in Pulmonary
and MICU volume. We should have two or three new attending physicians join us in July 2007.

Education: All division members participate in Grand Rounds, noon conference, and morning report.
The MICU lecture series and pulmonary lecture series are repeated monthly for interns, residents and
medical students. We all are guest speakers at many non-departmental conferences (Clinical Pathologic
Conference, ER Grand Rounds, Family Practice lecture series, M&M conferences, and Surgical Fellows
conference). We are planning to start a fellowship program in July 2008 or 2009, if infrastructure can be
improved, leadership agrees, and is stable.

Research: Members of the Division continue to participate in prospective clinical trials in critical care
medicine. Dr. Koch is active in the area of reducing medical errors and optimizing end of life decisions.
Dr. Cury has mentored resident-driven case reports and presentations. Administratively, the Division is
central to the success of the institution through provision of high quality MICU services, with Dr. Koch as
medical director. In addition, Division members serve medical directorships in other key institutional
service areas, including respiratory therapy and the arterial blood gas lab, the pulmonary function
laboratory and the sleep disorder center.


LISTING OF FACULTY MEMBERS


James D. Cury, M.D., Associate Professor and Division Chief

Medical School / Graduation date University of Miami 1981
Internship/residency and year Barnes Hospital/Washington 1984
Subspecialty training and year Washington University 1987

Kathryn Koch, M.D., Associate Professor

Medical School / Graduation date Johns Hopkins 1975
Internship/residency and year Medical University of South Carolina 1977
Subspecialty training and year Case Western 1979

Luis Laos, M.D., Associate Professor

Medical School / Graduation date Universidad Peruana Cayetano Heredia Medical School of Peru 1986
Internship/residency and year SUNY, Brooklyn 1995
Subspecialty training and year University of Florida, Gainesville 1998


Pulmonary & Critical Care


Pulmonarv & Critical Care


Division Chief: James D. Curv. MD


Annual Report AY 2007









PUBLICATIONS

Daniels J, Cury 3, Diaz J: An Unusual Cause of Post-Obstructive Pneumonia. Accepted to Chest for publication.
3/07.



CLINICAL ACTIVITIES


Inpatient Activity AY 06/07
Numbers of Inpatient Admissions 475
Inpatient Days 3170
Average length of stay 6.67
Number of IP Consults 749

Outpatient Activity
Clinic Visits 2115

Procedures
Bronchoscopies 202
Sleep Studies 464


CONTRACTS AND GRANTS


Pulmonary & Critical Care


Principal Sponsor Title
Investigator

Cury, James Alpha One Alpah-1 Screening and Detection Program
Foundation

Laos, Luis Novartis Phase III Trial, Community Acquired Pneumonia

Laos, Luis Takeda Phase III Trial, Severe Sepsis


Pulmonarv & Critical Care


Division Chief: James D. Curv. MD


Annual Report AY 2007








COMMUNITY INVOLVEMENT
ACADEMIC YEAR 2007 (7/06 6/07)


Linda Edwards, M.D., General Internal Medicine

Board Member, Attending Staff Foundation

Malcolm Foster, M.D., General Internal Medicine

Board Member, Attending Staff Foundation
Board Member, Florida-Georgia Blood Alliance
Board Member, Duval County Medical Society

Carlos Palacio, M.D., General Internal Medicine

Project Heal March 2007 (Ecuador) Served as attending for medical mission trip supervising
medical students from the University of Florida

Alan Miller, M.D., Cardiology

Chair of heart failure awareness week CME program Feb 13 Sterlings
Developed and hosted public forum on heart failure Sep 15, 2006 Wyndham
Chair of CME cardiology topics Sep 16 2006 Marriott at Sawgrass
Co-chair of CME internal medicine update Jan 27-28 Amelia island plantation

Lyndon Box, M.D., Cardiology

Media Activities
Interviewed by Jacksonville Magazine for an upcoming article on healthy habits for the
holidays
Two appearances on Channel 4 news morning show
Regarding hypertension and exercise
Regarding obesity and miss-diagnosis of asthma
Accepted position as a regular contributor for Jacksonville's "H Magazine." This is a widely
distributed personal health magazine aimed at the general public.
Subject of feature article for North Florida Doctor Magazine, currently in press
Article in submission to Health Partners Magazine on improving physician fitness
Will be featured on Channel 12 news and host a community call-in phone bank on November
29, 2006 for the community to ask questions about nutrition and personal health
Community involvement
Led the Shands Corporate Run team in February 2006
Spoke to Hammerhead Triathlon Club November 7, 2006 Audience of approximately 20
regarding cardiac exercise physiology
Rode with the Shands team in the MS 150 bike ride to help raise money for multiple sclerosis
research
Spoke to the Mandarin YMCA Silver Sneakers November 17, 2006 about exercise after age 65
Scheduled as speaker for "Shands at the YMCA" program to prepare people for the River Run.
In January, he will be giving two didactic lectures on exercise physiology to this group.
CME program for doctors- Submission currently being reviewed by the CME office

Annual Report AY 2007 Community Involvement


Community Involvement


Department of Medicine







C i l


Division of Cardiology, Staff Involvement


African American Summit
Breast Health Symposium
Sickle Cell Walk (Health Screenings)
Little Miracles Baby Shower (Health Screenings)
Westside Church of God by Faith (Heart Healthy Living-CVC Literature)
Heart Walk
United Way Campaign
American Heart Assoc. "Go Red for Women"
Chart Your Health Channel 4 Partnership
Jacksonville Senior Expo Health Screening


Ravi Kancha, M.D., Hospital Medicine

Attended a Community Education Diabetes Event where he spoke about Diabetes and
Hypertension
Participates in Career Pathing for Science and Medicine at Paxon High School

Ernst Michel, M.D., Hospital Medicine
Spoke at a health fair in Jacksonville, focusing on health screening, patient education and
male health
Gave a health care talk about diabetes and blood pressure in Orlando, FL


Community Involvement


Community Involvement


Department of Medicine


Annual Report AY 2007






Notes






Notes

































Department of Medicine


Annual Meeting June 2007
















Department of Medicine
University of Florida
College of Medicine Jacksonville
653-1 West 8th Street
Jacksonville FL 32209
904-244-8846
www.hsci.ufl.edu/im/




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