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From the Dean
Table of Contents
Research and innovation
Making the grade
on Safety &
Natural Products Herbal Medicine Food/Drug Interaction
In every issue of Gatorx, I ask our editor what the theme will be for the current edition. What I am
finding is that instead of a "theme" we try to report some of the great things going on in our II.. -
I am so full of wonder at what our faculty is doing in the research lab and the classroom that I find
it difficult to adequately communicate to all of you the exciting things that are currently in progress.
Please take a moment to review the : II 1'1 list for yourself. Each of these ,'ii.4 .i -. represent
current research topics conducted by our faculty:
* Pharmacist involvement for improved patient
care in rural health clinics
* Potential therapeutic agents for the treat-
ment of transusional iron overload related to
* Therapeutic agents for use as antineoplastic
* Public policy related to pain management and
* Herbal medicine therapy for pathologies such
as depression and anxiety
* The causes of glaucoma and ALS
* Therapy for geriatric memory dysfunction and
temporal lobe epilepsy
* The role of genetics in drug interactions
* A nationwide database to help identify
causes of resistance to antibiotics in specific
* Enhancing patient safety
* Mechanisms within the brain responsible for
feeding behavior and obesity to find therapeu-
tic agents for obesity
* Links between patients' adverse drug events
and improper medication use
* Methods to improve the lung selectivity and
reduce side effects of inhaled glucocorticoids
* Potential therapeutic genes and treatment for
* The impact of environmental chemicals on the
metabolism of drugs
* A genetic approach to the prediction and
optimization of drug therapy
* Improving therapy for children with asthma
* Angiotensin converting enzyme inhibitors
(ACE inhibitors) and angiotensin receptors
* Physiological adaptations during pregnancy
and these effects on major organ systems
* ii- i associated with the central nervous
system and Parkinson's disease and the contri-
bution of pesticides, heavy metals and infec-
tious agents to those pathological changes
* Neurological changes in ethanol addiction and
prediction of susceptibility to addiction
* Compounds for possible treatment of stroke,
traumatic brain injury, depression and drug
* Effects of drugs on patient quality of life and
the psychosocial aspects of elderly patients
and psychotropic drug use
* Automated systems, personal interviewing
approaches and pharmaceutical care models
that increase medication adherence, improve
health care outcomes and decrease total health
* Transient synthetic modifications of drugs to
improve delivery through biological mem-
* Gene therapy for diabetes, cancer and genetic
* Non-viral gene therapy for brain cancer
* Pharmaco-epidemiologic methods to evaluate
the effectiveness and safety of medications
* Cardiovascular disease and drug treatment
C II...1, I this talented group of teacher/scholars generated more than $8 million in grants
and contracts last year and is ahead of that productivity this year. Our faculty has improved the level
of productivity that ,11 .. I our II.... to move from up from No. 13 to No. 7 ranking among U.S.
schools and ,. 11-. -j of pharmacy in individual grants per FTE research faculty. At the same time,
these teacher/scholars have almost doubled the enrollment in the College of Pharmacy through the
use of distance education and additional instructional innovations.
What I have been observing over the last few years is the development of a II...,. faculty that
will truly revolutionize pharmaceutical research and teaching over the coming decades. Sure, the
players may change, but there is culture of success growing among our faculty which will be auto-
matically observed and absorbed by those who wish to join us over the coming years. I hope you will
join me in recognizing a i- I.. 111111 dedicated and talented group of teacher/scholars known as the
University of Florida College of Pharmacy.
William H. Riffee, Ph.D.
Associate Provost for Distance,
Executive & Continuing Education
Dean, College of Pharmacy
GATORx Magazine is produced by the
University of Florida College of Pharmacy
for its alumni, faculty and friends
Dean and Associate Provost of
William H. Riffee, Ph.D.
Executive Associate Dean
William J. Millard, Ph.D.
Associate Dean for
Michael W. McKenzie, Ph.D.
Assistant Dean for Distance,
Continuing and Executive
Sven A. Normann, Pharm.D.
Assistant Dean for Administration
and Financial Affairs
Associate Dean for Curriculum
L. Douglas Ried, Ph.D.
Kelly Markey, Director
Megan Bailey, Asst. Director
Director of Public Relations,
Editor GATORx Magazine
Linda Homewood, APR
JS Design Studio
10. research & innovation
trends in pharmacy
14. blackboard notes
faculty news, honors & awards
K0 THE COUER:
Profiling College of Pharmacy
educators who are leading
research efforts in herbal
medicine and drug
interactions. Read about
them in Features.
making the grade
spotlight on students
alumni & development news
reviving the study of herbal medicine
By Lisa Sperry
Veronika Butterweck, Ph.D.
Americans spent $4.13 billion on herbal supple-
ment sales in 2000, according to Nutrition
Business Journal. Some of the most popular
herbal supplements, including gingko biloba, St. John's
wort and echinacea, are purchased as ,11.. .. I remedies
for central nervous system disorders or as immune
system boosters. Herbal medicinal products have been
reported useful in 11.. i i, 11, almost any health problem,
including diseases of the respiratory tract; disorders of
the stomach, bowel, liver and bile; dermatologic condi-
tions; urinary tract disorders; inflammatory conditions;
and cardiovascular disorders.
Currently manufacturers and distributors do not need
Food and Drug Administration approval to sell dietary
supplements, including vitamins, minerals, and herbs or
other botanicals, but are responsible for determining their
safety. Still, medical studies have reported certain herbal
supplements, including St. John's wort, often used as a
natural antidepressant, may interact with prescription
drugs, rendering them ineffective.
"The emergence of interactions between St. John's
wort and certain prescription medicines has necessitated
regulatory action worldwide and has highlighted the need
for health-care professionals to have up-to-date scientific
information on the quality, safety and efficacy of these
products," said Veronika Butterweck, Ph.D., assistant
professor of natural products at the University of Florida
C II..1.. of Pharmacy.
The DeSantis Term Professorship in Natural Products
was established in 2002 through a $1.5 million gift by 1982
alumna Debbie DeSantis and her mother, Sylvia DeSantis.
Debbie is the daughter of the founders of Rexall Sundown,
a major manufacturer of herbal supplements.
While Debbie was a student, a professor named
Koppaka V Rao, Ph.D., of the department of medicinal
chemistry, taught pharmacognosy-the study of herbal
medicines-at the C II..'.. of Pharmacy. Known for his
knowledge of medicinal plants and folk medicine, Rao
shared his knowledge with students until his death in 1998.
Recognizing the void Rao's death left and that the
gradual loss of pharmacognosy in U.S. pharmacy schools
may close the door on the knowledge and potential benefits
of medicinal plants, Debbie and her mother made the gift to
establish the faculty position in the department of pharma-
ceutics, to focus on the biopharmaceutics, pharmacokinetics
and pharmacodynamics of natural products.
"I always regarded my natural products class as one of
the most interesting, informative, and practical classes I had
experienced during my pharmacy education. I also found
that the majority of pharmacists who had not been exposed
to such a class were very interested in the material," Debbie
The ,. II.... began an extensive search for a professor
with experience in teaching about herbal medicines. It
became evident that this was not a field of expertise easily
found in the United States.
"Through our ,. II I i, with European universi-
ties, we were very successful in recruiting a highly qualified
educator and researcher in herbal medicine," said Hartmut
Derendorf, chairman of the pharmaceutics department.
SButterweck came to UF in September 2003 from the
Institute of li-1, -- ,. 1i and Toxicology at the Westfalische
Wilhelms-Universitat, Munster, Germany, where pharmacog-
nosy is part of the curriculum. She became interested in the
field as a pharmacy student at the same university
Now, drawing on Butterweck's expertise, the C II.... of *
St. John's wo Pharmacy offers a course called Herbal Medicines for students
interested in learning about natural supplements. The course
4 introduces students to aspects related to safety, quality and
efficacy of herbal medicinal products, including techniques
for ensuring quality control, batch-to-batch consistency, r
specification concepts and relevant international guidelines.
Considering the distinctive characteristics of herbal medicinal
products, the course will address problems in the evaluation
of efficacy in pharmacological and clinical studies.
C, -II..g.. of Pharmacy Dean William Riffee, Ph.D., sees
pharmacists as having a vital role in recognizing drug interac-
tions and advising patients about the herbal remedies they
may be taking but not reporting to their doctors.
"Americans spend billions of dollars a year on natural
products. It's imperative that pharmacists have adequate
knowledge in this area," Riffee said. i i r
Ginko Biloba With the .. II... -. support, Butterweck is studying
herbal medicines with central nervous system activity She is r -
focusing on the investigation of plants with antidepressant or
anxiety-relieving activity, phytomedicines for the treatment
of restlessness and sleep disturbances, and herbal remedies
for the prevention of alcohol dependency. She also studies
the pharmacokinetics of herbal medicinal products, or how
the body absorbs, distributes, metabolizes and excretes these
products, which provides valuable information on potential
drug-herb interactions, aiding practitioners in prescribing
herbs safely and effectively
Butterweck cites the high degree of trust that the majority
Gundelia To rnefortli of consumers have in herbal medicines as one of the advan-
tages of botanicals.
"Furthermore, when compared with conventional drugs,
herbal medicines have fewer side effects, leading to a better
compliance of patients," Butterweck said. "The use of herbal
medicines can be recommended for the treatment of mild
to moderate disorders; for this indication, herbal medicines
might be superior compared to synthetic drugs." x
Debbie is delighted to see this specialty return to the
C II.,. of Pharmacy
"This was certainly an area worth reviving," Debbie
added, "Dr. Butterweck's expertise is a valuable addition to the
reintroduction of the study of herbal medicine."
Grad student Sasiporn Sarawek
College of Pharmacy teams with Tufts University to advance studies of
By Lisa Sperry/Linda Homewood
A new University of Florida research center is investigat-
ing how foods and drugs interact to prevent I i11
harmful side effects and improve patient outcomes.
The Center for Food-Drug Interaction Research and
Education, established by UF C II..1.. of Pharmacy and
the Tufts University School of Medicine, brings together
researchers in pharmacy, medicine and food science to
investigate known food-drug interactions and anticipate
Common use of prescription drugs combined with
daily consumption of over-the-counter medications,
herbal supplements, foods and alcohol makes this an im-
portant area of research for patients and their doctors.
Center researchers first will focus on the "grapefruit
juice effect," a phenomenon that has gained
widespread media attention since its dis-
covery in 1989. Scientists have learned that
grapefruit juice interferes with the body's
ability to breakdown certain drugs, increasing
"There is an immediate need for further
research to identify exactly which drugs
I ,- are affected by grapefruit juice and which
ones aren't so that drug substitutions can be
recommended," said center founder Hartmut
Derendorf, Ph.D., a distinguished profes-
l sor and chairman of the UF department of
B pharmaceutics. Derendorf directs the center
g with David Greenblatt, M.D., a professor and
chairman of the department of pharmacology and experi-
mental therapeutics at Tufts.
After seeing a 25 percent decrease in national sales
of grapefruit products, the Florida citrus industry turned
to research to answer consumer concerns. The U.S.
Department of Agriculture provided a renewable grant of
$232,000 to open the center last fall.
Steve Talcott, Ph.D., an assistant professor at the
UF C II..1.. of Agricultural and Life Sciences, joined the
center because of his research in phytochemicals the
compounds responsible for food interactions.
Established community outreach services and public
awareness programs through his II... -. Institute of Food
and Agricultural Sciences also makes this collaboration a
perfect fit, Talcott said.
With additional support from the federal Food and
Drug Administration and the Florida Department of
Citrus, Derendorf and others are working to develop a
research strategy that considers both the welfare of the
public and the grapefruit industry.
"Without up-to-date research providing factual in-
formation, patients sometimes feel that they should avoid
drinking grapefruit juice to be
safe," Derendorf said. "This is
not always the best solution
since the juice contributes
valuable health benefits."
Sharing its findings with
the public and health-care
community is one of the
center's main missions. Re-
searchers will provide specific
guidelines and dosing recom-
mendations, and educate the
public about the risks and
potential significance of food-
Plans include dissemi-
nating balanced and objec-
tive information through the
center's Web site (ww I 11
organizing scientific symposia
on food-drug interactions at
national meetings of physicians,
pharmacists and nurse-practi-
tioners; maintaining a speaker's
bureau available for lectures
and presentations to profession-
al groups and consumers; and
providing scientific consultation
with professionals working with
public media outlets.
Research and educational
efforts will expand to other food
products and to complemen-
tary and alternative medicines,
which have become increas-
ingly popular in recent years.
Derendorf, Ph.D. and
co-dir ecto Ve onika
Butterwe c, Ph.D.
"Many studies have begun
to identify prescription drug
interactions with natural
products such as St. John's
wort," said Veronika Butter-
week, Ph.D., center co-director
"We want to ensure the safety
and effectiveness of natural
products since interactions can
result in unwanted side effects,
toxic responses or treatment
Research groups are being
established at UF and Tufts,
with research and educational
activities monitored by the
center's Medical Scientific Over-
sight Committee. This commit-
tee has already had a meeting
with the FDA to get input on
regulatory concerns related to
food and drug interactions.
"We have been involved
in education and research at
the University of Florida for
80 years," said William Riffee,
Ph.D., dean of UF C II.... of
Pharmacy "Now, working with
researchers from several disci-
plines, we have an opportunity
to extend our ,. II.. .. service
beyond our own campus to
share research and to educate
to back) Immo
Victor de Castro
Study shows St. John's wort may compromise
cancer drug's ability to prevent relapse
By Linda Homewood
St. John's wort, an herb thought to be a safe, natural remedy
for mild depression, may interfere with a powerful cancer-fighting
drug's ability to prevent relapse in leukemia patients, Reginald F.
Frye, Ph.D., associate director for the UF Center of Pharmacoge-
nomics reported March 27 at the annual meeting of the American
Society for Clinical Pharmacology and Therapeutics.
Researchers who studied healthy volunteers to determine
whether the herbal preparation interacts with the prescription drug
imatinib mesylate, known by the trade name Gleevec, found that
taking the two together caused the amount of Gleevec in the blood
to drop nearly 30 percent.
Because it targets only cancerous cells, Gleevec has been
called a "magic bullet" drug that fights aggressive cancers such as
chronic myelogenous leukemia, researchers say. Leukemia patients
who go into remission must continue to take daily oral doses of the
medicine to prevent a recurrence.
"A 30 percent decrease in the level of Gleevec is significant
to cancer patients," said Frye. "It is the same as lowering the dose
-which is enough to allow for a relapse in the cancer growth."
Frye began the study while he was still working at the Uni-
versity of Pittsburgh Schools of Pharmacy and Medicine, prior to
arriving at UF's College of Pharmacy in 2003.
Patients should be aware that any product they take, whether
herbal, nonprescription or prescription, has the potential to alter
how their body handles other drugs they are taking, said study
collaborator Merrill J. Egorin, M.D., co-director of the Molecular
Therapeutics and Drug Discovery Program at the University of
Pittsburgh Cancer Institute.
"The interactions of herbal preparations and even certain
foods can be an important factor in how well a patient may absorb
or metabolize certain drugs, and those differences can have
important clinical consequences," Egorin said.
Clinical trials performed on St. John's wort in the
United States show that while it doesn't appear useful
for major depression, it may help treat mild depres-
sion, Frye said.
The first indication that St. John's wort interacts
with other medications came after physicians noted
drugs designed to prevent organ rejection weren't as
effective in transplant patients who were taking the
herbal supplement, he added. A few years ago, the
U.S. Food and Drug Administration issued a public
health advisory after federal research showed St.
John's wort interferes with medicines used to treat
patients with HIV. Those findings
raised concerns that the herb also
might interact with drugs taken
by patients with heart disease,
depression or seizures.
The National Nutritional Foods
Association reported in 2000 that
more than 242 million Americans
used some form of dietary supple-
ment, vitamins, minerals, herbal
remedies or specialty products. Al-
though St. John's wort is available
over-the-counter at most national
drug stores, little is known about
how it may interact with prescrip-
tion medications. Herbal products
aren't evaluated or regulated by the
FDA, and don't normally go through
the interaction studies required of
marketed prescription drugs.
"Often, patients don't think
of herbal supplements as
being a drug, and when
their doctor asks what other
medications they are taking,
they may not report taking
herbal products like St.
John's wort," Frge said.
"The emergence of studies such as this shows the need for
health-care professionals to have current scientific information
on the safety and efficacy of natural supplements," said Veronika
Butterweck, Ph.D., assistant professor of natural products at UF
College of Pharmacy.
For the current study, researchers focused on 12 healthy,
nonsmoking volunteers, six men and six women, who took one
400-milligram dose of imatinib mesylate. Researchers then took
a series of blood samples over a 72-hour period to see how much
of the drug had been metabolized. For two weeks after the blood
tests, study participants took 300 milligrams of St. John's wort
three times each day. On the 15th day, they again were
given one dose of imatinib mesylate, and the blood tests
were repeated to measure drug levels.
Frye noted a marked decrease of imatinib
mesylate in the subjects' bloodstreams after they took
S the St. John's wort regimen, indicating the herbal product
M caused the body to metabolize the medicine at a faster
Rate, weakening its effectiveness.
"Often, patients don't think of herbal supple-
ments as being a drug, and when their doctor asks what
other medications they are taking, they may not report
taking herbal products like St. John's wort," Frye said.
College honors three
leaders in pharmacy
The C II.... of Pharmacy presented distinguished pharmacy awards in May's
commencement ceremonies to two ,. II. -. alumni and a nonalumnus for their
significant contributions to the pharmacy profession.
Distinguished Pharmacy Alumnus Award
V. Ravi Chandran, Ph.D., who is now researching and developing several
innovative drugs with Signature Pharmaceuticals, received the Distinguished
Pharmacy Alumnus Award for his work in drug development and strong support
of the .. II. ..
Chandran earned a Ph.D. in pharmaceutical sciences from the UF C II.... of
Pharmacy in 1986 and in 1999 established the V Ravi Chandran Professorship
Chair for drug design and targeting in the UF C II.. .. of Pharmacy.
Chandran received his bachelor's and master's degrees in pharmacy from
Jadavpur University in Kolkata, India before attending UF He has since supported
pharmaceutical education by giving an endowment to establish the V Ravi
Chandran Center for Pharmaceutical Sciences and the V Ravi Chandran Endow-
ment Fund to promote graduate research and student scholarship in the C II.. .. of
V. R. Chandran Pharmacy at Jadavpur University.
He began his career as a senior research scientist with Sterling Drug Company
and has served as president and chief executive officer for both Signature Pharma-
ceuticals, Inc. and American Generics, Inc., both located in Bolton Landing, N.Y.
Distinguished Pharmacy Alumnus Service Award
This year's Distinguished Pharmacy Alumnus Service Award was presented to
Michael MacLeay, who previously served as president of the C II..4.. of Pharmacy
Alumni Association for two years, helped to develop a fund to build a new UF
M. MacLeay pharmacy building and assisted with the ,. II.... homecoming reunion.
He is recognized for his work with the alumni association and for playing a
major role in developing the UF pharmacy distance education campus in Orlando.
MacLeay graduated with a bachelor's degree in pharmacy from the UF C II.. .. of
Pharmacy in 1976, and he and his wife, Robin, are lifetime members of the UF
Alumni Association, members of Gator Boosters and longtime supporters of the
C .II.... of Pharmacy.
MacLeay began his career as a staff pharmacist at Florida Hospital Orlando,
and in 1979 he opened Douglas Square Pharmacy in Longwood, Fla. He later
started Nutritional Support, Inc., one of the first home infusion pharmacies in
Florida, in 1980. He served as the vice president of new business for Healthdyne,
T. D. Keith Inc. in 1987, started Parenteral Therapy Associates, Inc. in 1989 and founded and
served as president of ProHealth Medical, Inc. in 1990.
Distinguished Pharmacy Service Award
The Distinguished Pharmacy Service Award was presented to Thomas D.
Keith, Pharm.D., the operations administrator for oncology and director of the
m department of pharmacy for the Mayo Clinic at St. Luke's Hospital in Jacksonville.
x He received the award for his significant leadership in hospital administra-
I tion and hospital pharmacy practice in his career, his active interest in pharmacy
Education and for his contributions to the pharmacy profession.
o Keith received bachelor's and master's degrees from the School of Pharmacy
o at the University of Mississippi and continued his education at the Philadelphia
ruC II.. of Pharmacy and Sciences, where he received his doctor of pharmacy
E He has held several leadership positions in hospital practice and hospital
administration in the Southeast, including serving as the executive vice president
E and chief operating officer for Shands '.I II.. Medical Center, which he
p4 helped turn into a world-class pharmacy.
Do You Have the
If you are an independent pharmacist seeking
succession/exit strategy for business, or a
pharmacist looking to transition to independent
pharmacy ownership you will want to attend
this weekend workshop, August 27-29, at UF
College of Pharmacy.
* Business plans
* Selling your business
* Wealth succession & estate planning
* Managing for growth equity
* Retirement Planning
Our expert speakers will present case studies,
lead discussion groups and facilitate networking
opportunities. This productive learning environ-
ment with colleagues, who share your goals, will
empower you to start making career plans.
One inclusive fee of $395 includes two nights
hotel, and all weekend meals and activities.
Transportation is also provided to and from UF
campus. Registration is limited to 75 participants.
The course has been approved for 11 contact
hours (1.1 CEU). UPN: 012-000-04-119-L04
[ The University of Florida College of
SPharmacy is accredited by the Accreditation
Council on Pharmacy Education as a provider of
continuing pharmacy education.
For more information contact:
UF College of Pharmacy Development Office
(352) 265-8034, e-mail Kelly Markey:
firstname.lastname@example.org, or visit our Web site:
(-r) UF President Bernard
Machen, Ph.D., Dean
William : -it Ph.D.,
Advisory Board Chairman
Stephen Reeder, R.Ph.,
and Vice President for
& new beginnings
In fall 2003, the College of
Pharmacy had the largest entering
class of pharmacy students in the
United States. At that time, the .. II..,
three distance learning campuses completed
their first academic year. With 935 appli-
cants, the ,. II.... admitted a total of 306
a new students at four
L campus locations:
,, ,-, (4 8),
Orlando (52) and St.
This year, more
than 2,400 applica-
tions were received
UF President Machen speaks through a centralized
at the ( of Pharmacy's application service
spring National Advisory (PharmCAS) for 300
Board meeting. (PharmCAS) for 300
openings for fall 2004,
of which 1,854 were referred to the II..,..
for review and consideration. Fifty-five
percent of these applications were from
Florida residents and were given priority
for admission consideration. Nonresident
applications with superlative academic and
personal credentials were also reviewed.
The strength of the applicant pool insures
the continuity of a high-quality group of
new pharmacy students for the 2004 enter-
ing pharmacy class.
New developments are now underway
at UF as well. The UF Board of Trustees
unanimously elected James Bernard
Machen, Ph.D., as the university's 11th
president. Machen, who previously served
as president of the University of Utah,
assumed his new position January of this
President Machen addressed pharmacy
leaders and educators at the .. II.... -. spring
National Advisory Board meeting. His
message focused on the importance of
the role of advisory boards to professional
schools like the C..II .Z,. of Pharmacy.
"Professional schools must be grounded
in terms of what's going on in the world,
and advisory groups are one of the best
connectors between the academic world and
what I call, the real world," Machen said.
Machen also presented his belief that
I. I... within the university system should
be 11 .. a degree of independence to
chart their own course.
"The whole idea of the administration
is to help the faculty through the ,. II...
to do the things that they do best, which is
teaching and research," Machen said.
pharmacy students travel abroad
By Lisa Sperry
An exchange program linking U.S. and
European universities enables pharmacy
students to see firsthand how pharmacy
programs vary from country to country
The Transatlantic Mobility of Phar-
macy Students program gives students
the opportunity to travel abroad and learn
how pharmacy practice varies in different
cultural and political systems. Supported
by the U.S. Department of Education's
Fund for the Improvement of Postsecond-
ary Education, or FIPSE, the program links
schools in the United States and Europe,
creating a global classroom.
The program began in 2000, when
Chris Cullander, Ph.D., of the University
of California at San Francisco, obtained the
FIPSE grant totaling more than $200,000.
The University of Florida C II.. .. of Phar-
macy was one of four schools included
in the original proposal and has been a
program partner since its inception. L.
Douglas Ried, Ph.D., an associate professor
of pharmacy health care administration, is
the UF coordinator.
The C II.. .. of Pharmacy hosted six
European students and sent five students
to France, Spain and the United Kingdom
in 2003. Students traveling to UF send
Ried a "wish list"
of what they would
like to incorporate
into their learning
experience, and he
tries to accommodate
While at UF the
worked in a variety
of settings in the
UF Health Science
Center and the
the Shands at the University of Florida
Drug Information and Pharmacy Resource
Center, a regional drug information
center serving health-care professionals
(mentored by center co-directors Paul
Doering, M.S., and Randy Hatton, Pharm.
D.); Tacachale, a residential facility for
children and I.I. ..I I --.. i ,11l disabled
adults in Gainesville (Tom Munyer, R.Ph.,
and Mark Heller, R.Ph.); the C II.... of
Pharmacy Asthma Lab (Leslie Hendeles,
Pharm.D.); research laboratories in the
departments of pharmacodynamics and
pharmaceutics (Maureen K.- I'II-' .,. .I,
Ph.D., and Guenther Hochhaus, Ph.D.);
the UF Shands Eastside Community
Practice (Kristin Weitzel, Pharm.D.); and
Eckerd Pharmacy (Timothy-John Grainger-
Rousseau, Ph.D., R.Ph.).
Ried meets .......1 11I, preceptors
from host countries to assure experi-
ences will meet UF requirements. Before
traveling to international institutions, UF
students must be fluent in the language of
the country they will visit.
"As the program matures, we will
be working toward II i ,, the students
to acquire their community pharmacy
clerkship in the host country, as well as
one of their elective clerkships," Ried said.
Patricia Saunders in Barcelona, Spain
trends in pharmacy
"Students are officially students at UF
and pay tuition and fees."
Conceicao Ferreira, who was a
pharmacy student at the University
of Lisbon, Portugal, traveled to UF in
June 2003, shortly after completing
her pharmacy coursework there.
"The time spent in University of
Florida was absolutely unforgettable,"
Ferreira said. "At the same time that I
had the opportunity to work and learn
with excellent people and improve my
English skills, I also had the most amaz-
ing personal experience of my life."
During her visit, Ferreira observed
and participated in various clinical
pharmacy-related activities. She first
stayed in Tacachale, helping review
patient's drug regimens and attending
seizure and psychological clinical
The second part of Ferreira's
program was based at Shands at UF
primarily in the Drug Information and
Pharmacy Resource Center. There,
she helped answer patient-specific
questions received by the center. She
also participated alongside UF Pharm.
D. students in all aspects of their drug
information clerkship instruction,
presenting an article in the journal
club and taking part in weekly quality-
Ferreira, now considering
returning to UF for a doctoral degree
in pharmacy, had the opportunity to
visit cities throughout Florida (includ-
ing St. Augustine, Ocala, Orlando,
Tampa, St. ..I.. -i -i- and Miami), the
John E Kennedy Space Center at Cape
Canaveral and theme parks during her
Asthma assessment service
College of Pharmacy partners with Walgreens
By Linda Homewood
Conceicao Ferreira I. at work with recent Pharm.D. grad,
Erin Collins (back) at the UF Drug Information and Pharmacy
"The students also benefit by participating in
and experiencing cultures that are very different from
our own," Ried said. "Americans are sometimes very
ethnocentric, and it is helpful for the students to see
practices in other countries that are different and
possibly better than in the United States.
"On the other hand, when one sees things in
other countries, it also makes them appreciate the
good things about home, as well," Ried added.
"FlI I. .l11 it makes them more aware and sensitive
Although funding for the program ends this year,
Ried hopes to see it continue.
"We are trying to find alternative sources of
funding for students to continue the program to try to
offset a portion of the students' expenses," Ried said.
"Whether we are successful in developing alternative
funding or not, we will continue the program. If we
are unsuccessful, students will have to pay for the
whole program travel, food and housing -
The program is open to all UF pharmacy
students. For more information, e-mail Ried at
ried@. I ,1I .. I, or visit www.pharmobility.org.
We would like to extend a special thank you to our
students for their photo contributions.
(1-r) Sherry Gresser and Heather Myers Huentelman
As part of his UF
College of Pharmacy
residency training in
patient care, Michael
Ward, Pharm.D., has
implemented a new
service for Walgreens
to add to its patient
health screenings at its
Gainesville drugstore on
East University Avenue
and Waldo Road.
A community phar-
macy practice resident
at Walgreens working under UF faculty advisers
Kristin Weitzel, Pharm.D., and Brad Van Riper,
Pharm.D., Ward said he wants to educate asthma
patients on how they can get the best results
while following their doctor's prescribed plan.
Ward has been trained in the use of spirometry
- a breathing test that measures lung function,
which was previously available only in hospitals
or in a pulmonologist's office. Walgreens is the
first to offer the test in a community pharmacy,
By participating in the free service, patients can
learn why particular medications are used to treat
asthma, how they work and how to improve their
asthma condition. In private counseling sessions,
Ward teaches patients how to avoid asthma trig-
gers and demonstrates proper inhaler techniques.
All visits are documented and with patients'
consent their physicians are notified.
"Because it is easy for a patient to access a
walk-in clinic at their local drugstore, pharmacists
are in a position to aid physicians in treating asth-
ma patients," Ward said. "By helping the patient
to better understand asthma control, pharmacists
also help the doctor achieve a better success rate
in asthma therapy."
The Walgreens Patient Care Center, established
in 1998 in collaboration with the UF College of
Pharmacy, offers screenings for hypertension,
cholesterol, osteoporosis and diabetes in addition
to the new asthma service.
Nathalie Merle visits a pharmacy in Paris.
Michael Ward, Pharm.D.,
demonstrates a spirometry tool
You've invented a new drug that will improve people's lives dramatically, if only you can get it into their hands.
What's the fastest way to take your discovery from lab to market? If you said, 'Share my research results publicly
where other researchers and drug manufacturers can freely access the information,' you may be preventing your
groundbreaking research from ever benefiting anyone.
rom bench top to marketplace -
lBy Andrea Huisden
Pharmaceutical companies will not touch a technology
no matter how incredible unless they are fairly
confident their roughly $800k development investment
will ultimately be profitable. No drug will be profitable if the
company can't protect its interests in it and the only way to
do that is through the patent process. If a drug company finds
enabling information about your new pharmaceutical in the
public domain, unprotected, there's no way that company can
protect its interest either. So the best
route from your UF lab to drug store
shelves where people can actually -
access your discovery is through
the Office of Technology Licensing
Just ask Raymond Bergeron,
Ph.D., graduate research professor,
eminent scholar and Duckworth i
professor of drug development at UF
C II..1.. of Pharmacy. He worked for p
decades to better understand the role
of iron metabolism and polyamine Raymond Bergeron, Ph.D.
metabolism in disease processes. This
work led to the discovery of a number of new therapeutics.
Two of the drugs are now in clinical trials; one for liver cancer
and one for the treatment of iron overload disease in children.
Initially licensed by SunPharm Corp, Bergeron's tech-
nology then passed through the necessary preclinical and
early clinical trials. SunPharm was later acquired by Geltex
Pharmaceuticals, then by Genzyme Corporation, which is
now i, i I11111, the manufacture and ongoing clinical trials
of Bergeron's drugs. This is the last step before putting it in
But in order to get to the licensing stage, Bergeron went
through the Office of Technology Licensing. OTL works with
UF researchers to patent their work, a prerequisite for such
work to be licensed by a pharmaceutical company Licensing
involves the protected transfer of intellectual property, and
it's the only way pharma companies will accept university
Researchers like Bergeron have shown that it is possible
to share their discoveries with the scientific community and
to bring them to the marketplace as well. He is responsible
for 168 patent filings, 77 of which have issued. He has also
generated nearly 200 publications and several books. Almost
all of the patent filings were paid for by the corporate sector.
Knowledgeable about the complex patent process,
OTL negotiates licensing agreements like the one between
Bergeron and SunPharm. They assist researchers and
technology experts through the business process, which can
be difficult to navigate.
One of the larger university licensing offices in the
country, UFs Office of Technology and Licensing consis-
tently ranks in the top 10 of license revenue generation.
Inventors keep between 25 to 40 percent of net income from
a technology license as personal income, with the remainder
divided between the inventor's department, ,. II..g.. and
other UF programs to fund additional research. Income from
licenses has no strings attached and can be used for pioneer-
ing research that might otherwise be difficult to fund.
Licensing agreements can also lead to close relationships
between researchers and corporations that yield research
sponsorship or outright gifts and grants for basic research, as
well as job offers for UF graduates.
"We view our customers as potential long-term part-
ners," said Jane Muir, OTLs associate director. "Our relation-
ship with them does not end when the licensing agreement
is signed we continue to work alongside these companies
to ensure their success with our technology"
There are four basic steps in the OTL process:
1. First, you must recognize that you've conceived of or devel-
oped something unusual, unexpected, unobvious and usable.
2. Write a brief description of the discovery on OTL's Confi-
dential Invention Disclosure form (a streamlined version is
available online at www.otl.ufl.edu).
3. OTL's licensing team evaluates the discovery and researches
its patentability and marketability. This process often in-
volves discussions with the researcher to make an informed
decision on whether patent protection is appropriate.
4. Filing the patent: OTL facilitates the process with patent law-
yers to determine the breadth of claims. The licensing team
also works with inventors to identify corporations that might
make good licensing partners. They look for companies that
can provide resources and expertise necessary to take the
discovery through further development and through approval
processes of multiple agencies.
UF researchers propel FDA decision
to regulate pancreatic enzymes
By Linda Homewood
Leslie Hendeles, Pharm.D., a professor in
the ,. I I.. -. of Pharmacy and Medicine, calls the
recent decision by the Food and Drug Admin-
istration to regulate pancreatic enzyme replace-
ments "a huge step in the protection of patients
with cystic fibrosis."
Hendeles, also a clinical pharmacist in the
Pediatric Pulmonary Clinic at Shands at UF
medical center, has spent more than 10 years
documenting the health risks faced by cystic
fibrosis patients who
take unregulated generic
were available before
the 1938 Federal Food,
Drug and Cosmetic Act
and thus were "-g, ,, II ,-
thered" in escaping
dating back to 1989
Leslie Hendeles, Pharm.D., concred that s e
professor of pharmacy me products sm
and pediatrics enzyme products did not
provide consistent doses
or release of the enzymes, which could result
in treatment failure in patients with pancreatic
diseases, such as cystic fibrosis.
According to the Cystic Fibrosis Foundation,
cystic fibrosis is a genetic disease that affects
nearly 30,000 people in the United States. In
addition to causing changes in the lungs that lead
to chronic infection, the defective gene that causes
cystic fibrosis also impairs digestion, rendering
90 percent of patients dependent on pancreatic
enzyme replacement. Under the new ruling,
unless a manufacturer voluntarily withdraws
its product, it will continue to be available to
patients for four years.
Hendeles, a consultant to the FDAs pulmo-
nary division, said there were 30 to 40 cases of
treatment failure reported by doctors last year to
the Cystic Fibrosis Foundation.
A long-time activist
who has sought FDA regula-
tion of enzyme replacements
for years, Hendeles first
reported treatment failures
in three UF patients in
1990. Subsequently, he
conducted research with
Guenther Hochhaus, Ph.D.,
a professor of pharmaceutics
atUF C II.. .. of Phar-
macy, to analyze all enzyme
products on the market.
Published in 1994, their
research showed important
differences among products
and urged pharmacists
not to substitute one for
another. Although these
products are available on the
market, many have never
been tested in humans,
FDA officials said
manufacturers of pancreatic
enzyme replacements have
been notified their products
must be approved by the
agency within the next four
years in order to remain
available to patients. This
means product efficacy and
safety must be proven in
patients with CF
"It will still be several
years before the FDA weeds
out the unreliable products,"
Hendeles said. "Meanwhile,
it will be absolutely neces-
sary that pharmacists do not
substitute generic products
without discussion with the
UF Web site spotlights
If you visited the University of Florida Web site this
spring, you may have seen College of Pharmacy
Professor Paul Doering who was featured on the
home page spotlight (www.ufl.edu).
An expert on many drug issues in the news,
Distinguished Service Professor Paul Doering can't
afford to be camera shy.
Because when people need bottom-line drug
information, Doering is a bedrock source of reli-
able information a public resource.
For example, when ABC News reporter Jamie
Floyd recently prepared a report on diet supple-
ments for the "20/20" program, she needed an
expert. She called Doering, who co-directs the UF
Drug Information and Pharmacy Resource Center.
But members of the news media are not the
only ones who seek Doering's expertise. He
recently testified about national trends in prescrip-
tion drugs at a federal House of Representatives
subcommittee hearing aimed at developing strate-
gies to prevent prescription drug abuse.
An educator who understands how pharma-
cists' roles have changed in the past 30 years,
Doering hopes to shape his students into patient-
centered, pharmacy practitioners. Known for his
honest and direct approach to issues of drug use
and abuse, he sees education as something that
should be shared outside the classroom.
"As a pharmacist, I am in position to give
people the plain facts so that they can make
informed choices about any kind of drug use,
"Cystic fibrosis is a genetic disease that affects
nearly 30,000 people in the United States."
- Cystic Fibrosis Foundation
C of Pharmacy researchers working with the UF McKnight Brain Institute, I ..' left) Dr Katalin Prokai-Tatrai, Dr Laszlo Prokai and
Dr Alevtina Zharikova, are hopeful that new insight into how estrogen works could lead to better treatments for stroke patients.
by John Pastor
New insight into how estrogen works may lead to better
treatments for stroke patients, say researchers associated
with the University of Florida's Evelyn F and William L.
McKnight Brain Institute.
The hormone estrogen is commonly accepted as an
antioxidant that can minimize brain damage from stroke,
but it's not widely used therapeutically because of potential
side effects, including uterine cancer and breast cancer in
women, and feminizing effects in men.
Now, Laszlo Prokai, Ph.D., a professor of medicinal
chemistry at UF's C II.... of Pharmacy has solved the
mystery of how the body naturally regenerates estrogen
after a stroke, implicating a compound that he believes may
also provide estrogen's benefits without its risks.
Researchers at UF and the University of North Texas
Health Science Center II I i, I.. I to make the discovery,
which was reported in the Proceedings of the National
Academy of Sciences. More investigation is required, but
the findings may lead to therapies for post-menopausal
women who no longer benefit from estrogen's neuroprotec-
tive qualities, as well as for men who are at risk for stroke.
"During a stroke, free radicals damage important cells
in the body, most notably, nerve cells," said Prokai. "That's
where much of the debilitating effect of the stroke comes
from, not from the primary
incident the clogging of the
arteries and the shortage of
blood but after the surgeon
opens an artery, for example,
and the blood startsI i -
through the previously blocked
territory Then the reactive
oxygen species (free radicals)
just start going rampant."
Free radicals are unbal-
anced molecules than have lost
an electron and try to stabilize
themselves by stealing an elec-
tron from a nearby molecule,
which creates a jumble of
high energy particles that
ricochet wildly and damage
cells. In the case of stroke, the
hydroxyl radical a chemical
compound consisting of one
atom of hydrogen and one of
oxygen does a large part of
Estrogen comes to the
rescue by capturing the
"In layman's terms, a spill
occurs when the blood starts
:I into the blocked terri-
tory, and their ..II -hydroxyl
radical is the spill," Prokai said.
"The estrogen is the mop, soak-
ing up the hydroxyl radicals
before they do damage. But
when the mop is saturated, you
have to squeeze it to continue
mopping. This mechanism has
never been fully understood
When the estrogen and
hydroxyl radicals combine,
an unusual molecule called
a quinol is produced. In this
form, the hydroxyl radicals are
harmless, but the estrogen is
no longer useful as an anti-
oxidant. Prokai investigated
more deeply and discovered
chemicals in the body
transform the quinol back to
estrogen, effectively wringing
out the mop and making it
"It has been talked
about for years that estrogen
somehow participates in an
(antioxidant) cycle, and until
this work, no one really knew
what the cycle was," said Bruce
McEwen, Ph.D., a professor
of neuroendocrinology at
Rockefeller University in New
York. "The cycle implies that
estrogen doesn't have to be
used up, that it can be rejuve-
faculty news, honors & awards
Teacher of the Year
Gerald E. Gause, Ph.D., assistant scholar
in the department of pharmacodynamics,
is this year's recipient of the Teacher of the
Gause, who lectures on the physiologi-
cal basis of disease and pharmacological
basis of therapeutics, has received the
award from the College of Pharmacy twice
Gause and Dean irt in previous years. The award recognizes the
faculty member whose dedication to excellence in teaching represents the highest
standards of the College of Pharmacy and the University of Florida.
He received both his bachelor's and doctor of philosophy degrees in zoology
from UF and began his academic career as a research associate in the UF College
of Veterinary Medicine and later was appointed as a visiting assistant professor.
In 1980, he received the Freshman Class Teacher of the Year Award in the College
of Veterinary Medicine and was recognized by the freshman class of 1981 for his
dedication to teaching. Recently, Gause was recognized in Who's Who Among
America's Teachers for 2002 and 2004.
Gause's devotion to teaching is complemented by his interests in research ac-
tivities. Gause has also published several articles on perinatal pulmonary physiolo-
gy and pulmonary and systemic hypertension caused by endogenous compounds.
nated to produce a chemical shield that gets rid of free radicals
Further, you can use tiny amounts of the estrogen derivative to
set off this cycle. Showing a mechanism in which these effects
can take place is an important step forward."
In terms of therapies, scientists believe administering the
quinol the saturated mop will deliver the protective
benefits of estrogen, because the body will naturally wring it
out and convert it to estrogen, while side effects associated
with direct estrogen therapy, such as feminization in men, may
remain in check.
This could be a viable alternative to hormone replacement
therapy, which is a combination of estrogen plus progestin, a
synthetic substance that mimics the hormone progesterone to
oppose estrogen's undesirable effects on the uterus. While the
natural loss of estrogen as women age may contribute to higher
risk of stroke and heart disease, the American Heart Association
does not advise women to take hormone replacement therapy.
Furthermore, scientists at the National Heart, Lung and Blood
Institute in 2002 stopped a large study of such therapy because
it increased the risk of invasive breast cancer and blood clots in
the legs and lungs and failed to protect women from stroke.
"Many women are interested in hormone replacement
therapy, but they are afraid of the side effects," said James
Simpkins, Ph.D., a professor of pharmacology and neuroscience
at the University of North Texas Health Science Center and a
co-author of the paper. "But if a compound can retain estrogen's
protective benefits and reduce the side effects, because the
estrogen is produced in a controlled fashion in the body, it could
change the way one treats acute events, such as stroke and heart
attack, and chronic conditions such as Alzheimers disease."
Production of such a drug will require additional
experimentation, clinical testing and is at least five years away,
Faculty Recognition Award
Paul Doering, M.S.P, distinguished service professor of pharmacy,
was selected by College of Pharmacy students to receive the Faculty
Recognition Award for outstanding teaching
and service to students.
This is the second time Doering has
received the award, which recognizes an
Individual who has demonstrated continued
commitment to student achievement.
Doering, who is also the co-director of the
Drug Information and Pharmacy Resource
Center at the Health Science Center, has
earned the respect and admiration of students for his creative ap-
proaches to teaching pharmacotherapy, drug abuse and drug informa-
He has maintained an active clinical practice in drug information
services and made significant contributions to professional literature
in book chapters, journal articles and book reviews and has served as
an expert witness in several legal cases involving drug therapy.
Doering also has received the Teacher of the Year Award five times,
the most of any professor in history of the College of Pharmacy.
Medical relief to Honduras
In April, Doering volunteered with a
dozen other health care professionals to
accompany high school students on a
medical mission bringing relief to a small
town in Honduras.
They established a temporary clinic in
the west central part of Honduras near
Santa Rosa de Copan to bring health care
services to an area of the world where
otherwise there would be little to no
healthcare available. -
The group's mission was also to "bring With a hand-made sign, Doering
the message of hope to people who are declared himself "ElJefe de
disadvantaged in just about every way Farmacia" Chief Pharmacist.
possible," Doering said.
The group, which was comprised of mainly members of the Trinity
United Methodist Church, also included 15 high school students,
who gave up
their spring break X
to learn what it
means to sacrifice
for others and to
get the experience
of working in the
health care arena,
(l-r) Gabriel Ortiz, Casey Head and Ben Dunn help
pre-package vitamins for the children of Honduras.
Gyula Gdl (1) presents award with diploma to Bodor.
Bodor receives high
honor from Hungary
Hungarian President Ferenc Madl has awarded
one of his country's highest state honors to University
of Florida scientist Nicholas Bodor, Ph.D., D.Sc., who
was lauded for his contributions to the worldwide
scientific community in the field of drug development.
The Gold Cross of Merit of the Hungarian
Republic was given to Bodor as a representative of
Hungary in recognition of his many
achievements, including the successful
introduction of new drugs to the
marketplace and his leadership of the
research and development activities at the
IVAX Drug Research Institute in Budapest.
Bodor, a UF C II.... of Pharmacy graduate
Research professor emeritus who maintains
an active research program, also was
recognized for his work in pioneering the
engineering of drugs with improved effectiveness yet
fewer adverse effects.
The award was bestowed at a private ceremony
attended by Bodor's family and six dignitaries from
the Hungarian government, held May 19 in Budapest.
Istvan C -,11 Ph.D., the Hungarian Minister of
Economy and Transport, attended as President Madls
designated representative and the State Secretary, Gyula
Gal, presented the award to Bodor.
In his acceptance speech, Bodor noted the
numerous contributions from his collaborators and
students at UF as well as the IVAX Drug Research
"I would also like to thank my family," he added,
"for the support they have shown me through many
years of odd work hours and frequent traveling."
Bodor is chief scientific officer of the IVAX Corp.
and managing director and chief executive officer of
the IVAX Drug Research Institute in Budapest. He also
serves as executive director of UF's Center for Drug
Discovery, which he founded in 1986.
receives $3.5 million grant to
study drug effectiveness
based on genes ByLindaHomewood
he key to prescribing the right antihypertensive
medication may be as simple as knowing a patient's
genetic make-up. UF pharmacy researcher Julie A.
Johnson, Pharm.D., is on a quest to confirm that hypothesis,
armed with a $3.5 million federal grant.
More than 50 million people in the United States have high
blood pressure, according to the American Heart Association.
Although many antihypertensive drugs are available to treat the
condition, statistics show only half the patients treated have a
good response to any one of these drugs, Johnson said.
By studying genetic markers that might be related to
the response to blood pressure-lowering medicines, Johnson,
chairwoman of the department of pharmacy practice at the
C II.. .. of Pharmacy, said she hopes to show that the best
treatment responses can be predicted. This would mean patients
would be prescribed the drug best suited to their personal
genetic profile, eliminating or limiting the need to try multiple
drugs before finding the right one, she said.
Working with DNA taken from cheek cells, Johnson and
a team of 13 researchers will focus on a number of genes they
think are important to predicting response to blood pressure
medicines. If genetic markers for response are -..... I, ,1 I
identified, they could be used to develop a screening test. Such
a test would aim to help doctors determine which drug would
result in the best outcome for individual patients.
The beta-blocker atenolol and the calcium antagonist
verapamil, commonly prescribed to treat high blood pressure,
will be central to the study The variability in patient responses
to these types of drugs has been well-documented, said Johnson
a member of the UF Genetics Institute. Two other drugs used for
treatment hydrochlorothiazide, a diuretic, and trandolapril,
an angiotensin-converting enzyme inhibitor will also be
studied to see how their effectiveness is related to specific genes.
The data and genetic samples being analyzed in this research
were collected earlier from patients in a large clinical trial.
Johnson's four-year award from the National Institutes of
Health was made possible by a collaborative UF effort initiated
in 2001. While conducting clinical trials in hypertension
pharmacogenetics, Johnson and Carl J. Pepine, M.D., UFs
chief of cardiovascular medicine, saw a real need for early
investment funding that would enable them to begin II.. .i, ,
large numbers of genetic samples from patients with high
blood pressure. These patients were participating in a large
international trial led by Pepine called the International
Verapamil SR-Trandolapril study, or INVEST.
The UF Division of Sponsored Research agreed to provide
$100,000 of the initial funds. The .. II.... -. of Medicine and
Pharmacy added to the investment, providing a total of
$175,000 for Johnson to continue her work. Johnson credits
faculty news, honors & awards
Julie A. Johnson, Pharm.D., department of
pharmacy practice chair
this UF seed investment with helping to
secure a small NIH grant,: II .. I by a
larger grant from Abbott Laboratories, the
sponsor of the INVEST trial, and finally
the $3.5 million grant from NIH. Thus,
in a period of less than three years, the
$175,000 investment made by UF led to
more than $5 million in external funding.
"We felt that if we could begin
genetic sample collection, we might be
able to secure substantial funding for our
future research, but without these samples
in hand, acquiring such funding would be
difficult," Johnson said.
Then, working with Pepine and
Rhonda Cooper-DeHoff, Pharm.D., a
research assistant professor in the C I I..
of Medicine, Johnson began II. .,,,I"
genetic samples in spring 2001. By late
2002, 6,000 genetic samples had been
collected by having study participants in
INVEST provide a sample of mouthwash
they had gargled.
With such a large sample population,
Johnson built the foundation for her study
and was able to continue by developing a
research plan with a cross-departmental
team, mostly comprising .- II.. g.... from
UF's .. II... .. of Pharmacy and Medicine
and also II 1 ,- from three other
universities. Last fall, she received
notification that her team was to receive
the $3.5 million NIH grant for the study of
"The work that Dr. Johnson is
doing with Dr. Pepine and others is
very exciting," said Kenneth Berns,
M.D., Ph.D., director of the UF Genetics
Institute. "The link between patient
genotype and response to drugs is the
cutting edge of patient care. Beginning
with this new look at the treatment of
hypertension, I think there will be cross-
over to treatments of many other health
conditions in the future."
Meet Our New Faculty...
Department of Pharmacodynamics
Dorette Ellis, Ph.D., Assistant Professor
Dr. Ellis was an instructor in Neurobiology at Harvard
Medical School since 1998. She joined the department of
pharmacodynamics in January 2004. Her research focuses
on the Na,K-ATPase protein, which is responsible for fluid
regulation. Two diseases that can result from increased fluid
build up are central to her research. One disease, glaucoma
is the leading cause of blindness in the U.S. It is caused by
excessive fluid that increases pressure on the optic nerve. An-
other disease, hydrocephalus, is caused by excessive accu-
mulation of cerebrospinal fluid, with infantile hydrocephalus
occurring in one out of 2,000 births. By better understanding
how this protein can be regulated, Dr. Ellis hopes that new
drugs can be developed to prevent these diseases.
Department of Pharmacy Practice
Issam Zineh, Pharm.D., Assistant Professor
Dr. Zineh joined the college in Aug. 2001 as a post-doc-
toral fellow in cardiovascular pharmacogenomics. Through
Dec. 2003, he taught pharmacy students, and conducted
research in genetics related to drug response in people with
high blood pressure and heart failure. His current research
is focused on how cardiovascular and endocrine drugs,
commonly used to treat high cholesterol, hypertension, heart
disease and diabetes, regulate immune functions.
Office of Distance, Continuing
and Executive Education for
the College of Pharmacy
Diane Beck, Pharm.D., Director of Educational Initiatives
Dr. Beck was a faculty member of the Harrison School of
Pharmacy at Auburn University for 25 years before joining
UF College of Pharmacy in April 2004. Her responsibilities
now involve student assessment, quality assurance of clinical
activities and curriculum review/revision for the Working
Professional Pharm.D. program and to collaborate with
faculty and staff in enhancing the delivery of the Distance
Honors & Awards
Hartmut Derendorf, Ph.D.
Professor and Chairman of Pharmaceutics,
Director of the Center for Food-Drug
Interaction Research and Education
President-elect of the American
C II. .,. of Clinical i-. -- I : He will
begin his two-year term as president in
2006. Derendorf has previously served as
a member of the Board of Regents and as
secretary of the ACCP
In 1969, the organization was
founded and dedicated to a new branch of
pharmacology that dealt with the effective-
ness and safety of drugs in man, and
today it has a membership of about 1,000
Earlene Lipowski, Ph.D.
Associate Professor of Pharmacy
Health Care Administration
Elected as the 2004-05 president of
the American Pharmacists Association's
Academy of Pharmaceutical Research &
Science and will serve on the APhA Board
APhA, the national professional soci-
ety of pharmacists, is the first established
and largest professional association of
pharmacists in the United States. Its more
than 50,000 members include practicing
pharmacists, pharmaceutical scientists,
pharmacy students, pharmacy technicians
and others interested in advancing the
Lipowski also has been appointed
through the American Pharmacists
Association as the representative to the
Pharmaceutical Sciences Section Commit-
tee of the American Association for the
Advancement of Science.
Lipowski is serving a three-year term
that will end February 2007. She will serve
to promote pharmaceutical sciences and
assist in arranging programs for presenta-
tion at the annual AAAS meetings. She will
serve as a liaison between the APhA the
The AAAS is the world's largest
general scientific society whose mission is
to foster the exchange of knowledge of all
disciplines of science.
Diane Beck, Pharm.D.
Director of Educational Initiatives at the
C',ji. : of Distance, Continuing & Executive
Education for the College of Pharmacy
Elected to serve as the president of
the American Association of C II. .. -. of
Pharmacy starting July 2004 and ending
Beck, who joined the UF faculty in
April 2004, is also the recipient of the
AACP's Robert K. Chalmers Award as
the distinguished pharmacy educator for
2004. It will be presented to her at the
group's annual meeting in July.
Founded in 1900, the AACP is a
national organization representing the
interests of pharmaceutical education and
educators and is comprised of all 89 U.S.
pharmacy II.. -. and schools.
Grants & Awards
Carrie Haskell-Luevano, Ph.D.
Assistant Professor of Medicinal Chemistry
Received a new grant from the
National Institutes of Health entitled
"Characterization of Human Melanocortin-
4 Receptor Polymorphisms."
Haskell-Luevano will study mutations
of the Melanocortin-4 Receptor protein
that have been identified in morbidly
obese humans. The purpose of the
four-year grant, of nearly $993,000, is
to attempt to design drugs that can treat
these specific mutant proteins to reduce
the associated obesity
Julie Johnson, Pharm.D.
Professor and Chairwoman of Pharmacy
Practice, Director of the Center for
2004 Leon L. C. I II.. ,Young Inves-
tigator Award, received from the American
Society for Clinical .li- 1 -- i and
Johnson was : 1 ,II, recognized
at the annual ASCPT meeting in Miami
Beach on March 25, 2004 where she gave
a keynote address and then received a
commemorative plaque and a $1,000
The award was established in 1986
with the purpose of encouraging and
recognizing young scientists active in the
field of clinical pharmacology.
Issam Zineh, Pharm.D.
Assistant Professor of Pharmacy Practice
Received a three-year Scientist
Development Award of $240,000 from the
American Heart Association Florida/Puerto
His project, called "Systemic Immu-
nomodulatory Effects and Pharmacogenet-
ics of Atorvastatin in Early Atherosclero-
sis," begins July 1, 2004.
Jason Frazier, Ph.D.
Assistant Professor of Pharmacodynamics
Received a one-year, $75,000 award
from the University of Florida McKnight
Brain Institute to support his work on
Frazier looks to obtain detailed
mechanistic information about how the
cholinergic system normally works in
memory processing with the hopes of
identifying more specific targets and more
precise goals for therapeutic interventions
that are designed to address age-related
faculty news, honors & awards
Pharmacy students convene for first
patient care colloquium
By Lisa Sperry
University of Florida pharmacy students from four statewide campuses
met recently in Gainesville for the Patient Care Colloquium, a new program
designed by faculty to help students improve their communication and
problem-solving skills related to patient care. I
he two-day program, held in
March, included a course in
professional communications and
two in pharmacotherapy, the use of drugs
for the treatment of disease and mental
illness. The program's goal was to help
prepare second-year professional pharmacy
students for communication with patients
and health-care providers and to simulate
patient-care experiences through active
learning exercises and demonstrations of
Carole Kimberlin, Ph.D., a profes-
sor, and Lynda McKenzie, R.N., M.Ed., a
clinical associate professor, coordinated the
professional consultation activity through
the Harrell Professional Development
and Assessment Center at the UF Health
Science Center. In this state-of-the-art
facility equipped to conduct standardize
video recordings of patient consultations,
students incorporate interviewing skills,
patient education, and new prescrip-
tion counseling. Paul Doering, M.S., a
distinguished service professor, Tom
Munyer, M.S., a clinical associate profes-
sor, and Bernadette Belgado, Pharm.D., a
clinical assistant professor, coordinated the
students' activities in a pharmacotherapy
patient case study
"We saw this as a great opportunity to
bring our second-year students from three
distance learning campuses to Gainesville,"
said Michael W McKenzie, Ph.D., R.Ph.,
associate dean for professional affairs.
Through this new program, the. I. II..,.
faculty and administration hope to create
new avenues for students in each profes-
sional-year class within the four-campus
program to convene not only for meaning-
ful and .. I, I I.. -1,1 ii. learning experiences,
but also for an enjoyable professional and
As part of the Professional Communi-
cations class, students were video recorded
during a 30-minute simulated patient
consultation. The activity enabled students
to practice interviewing, educating, and counseling a
patient on a new prescription. Standardized patients used
scripted patient roles to provide consistent interviews for
students. The students were evaluated on their ability to
assess how well therapeutic goals are being met for the
patient and address problems that the patient may be
having with current treatment, as well as to assess the
patient's understanding of the newly prescribed medica-
tion and provide information the patient needs to manage
a new therapeutic regimen effectively
In this simulated yet realistic setting, students had
the opportunity to practice their patient interview skills,
preparing them for working with real patients during their
internships later on, Munyer said.
Students also were assessed on how well they
recorded the patient interview in a SOAP (subjective,
objective, assessment, and plan) note, used for medical
documentation. The SOAP note details what a patient
tells a health-care professional, what the professional
observed, what the professional thinks the patient is
experiencing, and what will be done to help the patient.
"They can't assume that the records they have
been given are complete," Munyer said. "It requires
problem solving to document accurate patient-care
information, while at the same time demonstrating
The pharmacotherapy classes enabled the students to
work together on a patient case study All campuses were
represented in each study group of five to six students.
After evaluating a case together, the students reported
back to the class. They were called upon to interact with
A first-time approach to educating students in hands-
on patient interaction skills, Munyer said the Patient Care
Colloquium was successful and impressive.
"Working together to meet .li. II.. -.in developing
their communication and problem-solving abilities, the
students also have an opportunity to socialize with their
peers," McKenzie said.
"The demanding day of learning also should develop
an 'esprit de corps' among the students," McKenzie added.
Each day ended with an in-depth clinical discus-
sion of the case, remarks from C II. .. of Pharmacy
Dean William Riffee, Ph.D., and an interesting and
entertaining videotape on professional communications
produced by the American Society of Health System
Pharmacists. Students also gathered for a pizza social.
I ,Spring 2004
professional coating ceremony
.%C ... A L J-I. jh
Pledge of Professionalism
At this time, I pledge to develop
a sense of loyalty and duty
to the pharmacy profession.
I will accept responsibility
for membership in the
I will pursue all academic ;' 'A..
and professional campus receives her white coat r
endeavors with integrity. from Executive Associate D
Bill Millard, Phl.'
I will foster professional
through life-long learning.
I dedicate my life and
practice to excellence.
I accept the responsibility
pharmaceutical care to patients.
I commit to abiding by the
Oath of the Pharmacist and
2 the Code of Ethics for -Student speaker and graduating
Pharmacists as I advance toward senior Marfreeia Clarke
full membership in the profession.
SI voluntarily make this
C>pledge of professionalism.
o Richard and Lisa
completedfirst year of
Student speaker for
Class of 2004
Keith Teelucksingh was selected by the
graduating seniors in the Doctor of Pharmacy
degree program to have the
honor of giving remarks
about their time and
experiences in the C. II .1. of
Keith attended the New (above photo)
C.II. at the University Front: Amanda Tjiong,
of South Florida where he Ephane w
Erin Crawshaw; Back:
received a B.S. degree in Cary Ferree (05),
neurobiology He participat- Leslie Masem, Kevin
ed as an undergraduate in a National Institutes Ferguson, Melissa
of Health grant in neurobiology and presented McCracken
the research results at a poster session held at
the Society of Neuroscience in Los Angeles.
He was a member of the Academy of
Students of Pharmacy (ASP), the Student
Chapter of the Florida Society of Health-System
Pharmacists and has served on the C..II,. of
Pharmacy Curriculum Committee as a student
representative. Keith has been supportive of
events in the C .II,.,. of Pharmacy such the ASP
Cultural Dinner, National Pharmacy Week, the
Mobile Health Care Unit and Legislative Day in
Keith has worked with Walgreens as a
pharmacy technician. After graduation, he had
plans to attend the School of Pharmacy at the
University of California at San Francisco as a
pharmacy practice resident.
Working Professional Doctor
t of Pharmacy Graduate
After three years, it was a pleasure to meet the
faculty and staff who are such an important
part of the WPPD program.
Graduation was truly an experience not to be
forgotten or missed. Words cannot express
the pride and emotion felt by myself and my
family as I 11 I. L across the stage to shake
your hand. My children, wife and I will always
cherish the time spent at Gainesville."
Anthony J. Vitale, Pharm.D.
WPPD graduate from Cheshire, CT
Assistant Dean Sven Normann with Vitale
Student Awards and Recognition
College of Pharmacy graduate student wins
APhA best paper award in clinical sciences
Sharrel L. Pinto, Pharm.D., a
UF C II... of Pharmacy student and
research coordinator, is the recipient
of the 2004 American Pharmacists 7
Association Academy of Pharmaceuti-
cal Research and Science Postgraduate
Best Paper Award in the clinical
Awards are presented annually by the APhA to one
paper in each of three categories: clinical sciences, economic,
social and administrative sciences and basic sciences. Each
award recognizes the best contributed papers by postgraduate
authors, presented at the APhA annual meeting in Seattle,
Wash., March 26-30.
The award is given on the basis of originality of the work,
rigor of the experimental methods, clarity of the presentation
of the results, appropriateness of the conclusions, potential
significance of the study and overall quality of the presentation.
Sharrel won the award, a $500 honorarium and a certifi-
cate, for her paper, Evaluation of Pharmacists Interventions
in Diabetic Patients from Rural Community Health Centers.
Pintos research interests include adherence of ethical guidelines
by physicians and disease management and health care quality
improvement for diabetic patients. She is also the recipient of the
UF Outstanding International Graduate Student Award in the
pharmacy health care administration department.
APhA national patient counseling competition for
Cary Ferree was selected as one of five
students among ,. II.. -. of pharmacy to receive
the Pharmacy Student One-to-One Counsel-
ing Recognition at the American Pharmacist
Association annual meeting held March 26-29.
The award recognizes exemplary one-
to-one patient counseling resulting in better
health, superior communication and improved
outcomes for their patients.
Spring semester, Cary was president of the Iota Chapter of
the Phi Lambda Sigma chapter. She was chosen by a panel of nine
judges from the Pharmacy Student Editorial Advisory Board.
Cary, who was guest of honor at the APhA 2004 opening
reception, received airfare to Seattle for the 2004 APhA annual
meeting, three nights' hotel accommodations and full complimen-
tary registration to the meeting.
Al and Belle Meyerson Scholarship
Resident of Broward County, academic
performance and financial need
Academic performance and an interest
in community pharmacy
Brevard County Pharmacy
Resident of Brevard County, academic
performance, currently a second or
third year professional student
David W. Ramsaur Award for
Binh Nguyen and Lisa Taylor
Deserving student who has excelled
Eckerd Pharmacy Scholarship
Shawn Anderson, Kimberly Austin,
Amy Barnett, Bita Bijanfar, Michelle
Demus, Erika Diaz, Judy Duncan,
Felicia Fong Kong, Kinh Huynh,
Marie-Therese Jackson, Leandre
LePorte, Benjamin Lowe, Russell
McKelvey, Jennifer Mize, Adriana
Natoli, Shenjin Paul, Sarah Rainey,
Amanda Sartin, Denisse Reyes, Carol
Stauffer, Rebecca Turville, Wisener
First Coast Award
Resident of Baker, Clay, Duval,
Nassau or St. Johns counties prior to
enrollment; demonstrated academic
excellence; well rounded as exhibited
by regular participation in community
and student activities
Claudia Lopez and Amanda Sartin
Interest in pursuing career in hospital
Rx, open to current second or third
year students in the PharmD program.
Applicants must include a letter stating
interest and experience in hospital Rx
and completion of FSHP membership
Victor Micolucci Memorial
Preference to orphans, community-
oriented students without parental
North Central Florida society of Health
System Pharmacists Award
Interest in hospital pharmacy, leadership/
extracurricular activities. Priority given
to students currently in their second
professional year. Must submit a short
essay describing the role of hospital
pharmacists/own experience in hospital
Pinellas Pharmacists Association
Students from the Tampa Bay area, must
be able to attend one scheduled meeting
for introduction to the membership.
Walgreens Company Scholarship
William Terneus Jr.
Student in 3rd or 4th professional year
with high scholastic standing, financial
need, strong leadership qualities. Must
show a desire to enter community
pharmacy practice and have current/
previous experience in community
pharmacy. Must submit a letter describ-
ing his/her experience in a community
spotlight on students
Student award essay challenge IN MEMORIAM
Senior Heather Myers-Huentelman, was selected
as the third-place winner in the Seventh Annual US
Pharmacist Essay C i-, .II. 1-.. competition for her essay on
the treatment of insomnia.
The essay was selected by the C II.... of Pharmacy's
Financial Aid and Awards Committee to be its representa-
tive in the national competition.
Heather and the ,. II.... each received a $250 award,
and she was recognized in the US Pharmacist December issue.
She entered the contest while completing three months of pharmobility
exchange rotations at the University of Bath in the United Kingdom. Before
graduating, Heather was a member of the American Society of Health-System
Pharmacists, Florida Society of Health-System Pharmacists, Kappa Epsilon,
and Rho Chi.
"I thought the contest was a great opportunity to learn more about
insomnia and to compare pharmacy practice in the United Kingdom and the
United States," said Heather.
NACDS Awards: national organization
for chain drug stores
dT ^ J r This year, four C II. of Pharmacy students
received awards from the National Organization for Chain
Drug Stores Foundation.
l Mary Hopple, Heather Hardin and Cary Ferree all
received the NACDS Foundation Pharmacy Student
Scholarship, and Kimberly Terhune, from the I..
S,.I ,-, ,II.. distance learning campus, was one of
rn four students who received additional recognition by
Kimberly Terhune being awarded the Robert J. Bolger Scholarship. The
scholarship is donated by Barr Laboratories and named for its former board
member and past NACDS president. The awards are given each December.
The students were all recognized with scholarships from the organiza-
tion, which received about 400 applications from 77 pharmacy schools and
awarded a total of 25 scholarships to future leaders of chain community
pharmacy. The foundation has provided more than $1.1 million in support
to U.S. schools of pharmacy and students in the past.
Claire Somera Duncan
Members of the graduating class
of 2004 wore green ribbon lapel pins
to honor a former classmate, Claire
Duncan, who was meant to join them
While traveling in May 2001,
Clairet, ti ,. 11 died in a car accident.
She had been admitted to the C II....
of Pharmacy in 2000, and was working
toward her doctor of pharmacy degree.
The loss is deeply felt by her
family, .. II pharmacy students and
the faculty of the C II..1.. of Pharmacy.
In her memory, the student chapter of
the Florida Society of Health System
Pharmacists presents the Claire Somera
Duncan Leadership Award each year to
a deserving pharmacy student.
Claire was a member of several
pharmacy student organizations,
including FSHP and was a recipient
of the FSHP scholarship award. She
showed promise in her academic
work and pharmacy career and will
be remembered by the C II.. ..
of Pharmacy faculty and senior
class of 2004 as a bright,
beautiful and dedicated person.
Heather Hardin, Dean 'I 1 Cary Ferree and Mary Hopple
Fall 2003 reunion
On April 15. tile College ,if
Pharmacy held His 17[h Anr.
rual Research Sho:,wcase
and Awards Recognition Day
Divided in[r:, wo categories.
the compeil ion had three
WNinners in [lite oral division
and hlree winners in the
poster division The event
was sponsored by threee Col. .. ,
lege ..f Pharmacy Aluni n
SRober Bell Ph 0 of Barr
Laborat-ries (and Maria Bell).
Francisco Alvarez Ph 0 of Andr.. Corp and Robert Levlt Ph 0 (and
Poster Competition Winners:
Graduate Student Mei Tang
Title rAAV1 Il iedthted h.4AT Gene Therap1 Il modulate Cellular Im-.
Postdoctoral Fellow (Two pocst-doc winners tied)
Department Pharmacy Practice
Title C~ rochromne P450 3AJ. .A5. and P1gl coprowein as Pharima
co'gei'onic Predictors of Tacrolhnnus Phartnacoknetics and Clinical
Outcomes 7n ii er Transplant Recipients
Title H/hh Temporal Resolution Anal\ sis o Iveuroiransmniters U[ lizing
Onlhiioe Caplllar\ Electrophoresis n ith laser-induced Fluorescence
Oral Competition Winners:
Junior Division Aleksandar Todorovic
Department Medicinal Chenistry
Title Peptide Bond Ai Ioditcations o 11 lelanocortm A.gonists Result i
Coni ersioin of the Agonrist into an .4Antagonist
Levitt Divisiion Michael Taylor
Department Pharmacy Health Care Administration
Title Surger\ Versus Radiation: Is there a difference in Prostate
Cancer- specilc 1A lorralir, '
Senior Division Bonian Irani
Department Medicinal Chemistry
Title Benefits of Vohlumar\ E.ercise i Controlling Obles;ii and Sexual
\I Stunciion 1i iAlelanocortin.- Receptor DefLcient i lice.
Kappa Epsilon members raised money at the 2003 reunion by
having bidders choose faculty member to receive a pie in the
(-Ir) Bethany TZ I
volunteer at FSHP
2004 College of Pharmacy
Walgreens representatives present a check to Dean ia for student support.
reach out to alumni
ASP 3rd Annual
face. The highest bids were tied between (1-r) Professor
Paul Doering and Executive Associate Dean Bill Millard.
Anne Rafidi and
at SNPhA booth
;' I- T-shirts
1- .11. 1 Iif 11 1 1 Ill1I. I I.
I II I
II I 1,. 1 I, -,
i ..i I I.. III. ii.. 1. .III I
*Atkinson's Healthcare Providers
*Caremark Rx, Inc.
*Indian River Memorial Hospital
* K-Mart Corporation
*Medco Health Solutions
*Memorial Healthcare System
*Rite Aid Pharmacy
*Sacred Heart Health
*US Air Force
I' I' i I i I
Next year's Career Days will be held January 21-22, 2005
at UF's new College of Pharmacy building HPNP complex.
Thanks to our 2004 Participants:
spoi.'ll~Lg/l 111 111 NII(II111%
LETTER FROM YOUR ALUMNI PRESIDENT Alumni Reunion
SDear Fellow Gators,
C What an exciting year! As president of
the University of Florida C II.... of Phar- .
macy Alumni Association, I would like to tell
you a little about what is going on in my life
as well as in the life of our alma mater.
I can't believe it has been 25 years since
I II .. I out the gates of the University of
Florida and into the pharmacy profession.
Since that time, I have spent 11 years in
hospital pharmacy and 14 years in com-
munity pharmacy. While I practiced hospital
pharmacy, mostly in Central Florida, I held several offices with Central
District Florida Society of Health-System Pharmacists (I ,-,1II1 called
Hospital Pharmacists). When I moved to beautiful Brevard County 14 Dean i greets Bert Smith.
years ago, I started my career in community pharmacy practice and
became a member of Brevard County Pharmacy Association as well as
its executive committee. Eve.i ,i,,, II I became president of BCPA and
also became very involved with the Florida Pharmacy Association and
the American Pharmacists Association. In the midst of all this, I got
married and have a wonderful husband and a beautiful 13-year-old
daughter. F-, II, this year I will be installed as president-elect of the
Florida Pharmacy Association.
Looking at my calendar, the C I... of Pharmacy has enough to
keep us all busy this fall. The first big event, the 2004 Reunion Week-
end, will be held on September 10-11 at the new pharmacy building.
The weekend begins with an opportunity to earn two hours of CE
credit on Friday afternoon II .. I by a class party. On Saturday, we
will all meet in the courtyard for barbecue and catching up with old
friends. Later that day we will head up to the Swamp to watch the
Gators play Eastern Michigan.
The class of 1954 will also celebrate a special reunion this year
during Grand Guard weekend on October 1-2. This campus-wide
event will help the class of 1954 commemorate their 50th reunion. Albert and Alberta welcome students and alumni.
That same month, on October 15, the I.. will host the 11th an-
nual Ken Finger Memorial Day and Golf Tournament. The day will
begin with three hours of continuing education in the morning and
an afternoon on the course at Haile Plantation. The funds raised from
this event will help support graduate :.. II I-
I am proud to be a Gator because we have one of the best II...
of pharmacy in the nation wi I-1, 11i, ,. ..,,,-I faculty, students
who are involved with their professional organizations and alumni
who are well respected by their peers for their work with professional
organizations. Many I:I Gators have worked hard to advance the
profession of pharmacy and to make pharmacists a respected member
of the health care team.
0 I look forward to seeing you in Gainesville this year.
Go Gators! Kirsten and Philip Diaz enjoy Friday's
Kathy Petsos, R.Ph.
Class of 1979
2004 C ... of Pharmacy Alumni President
alumni & development news
Deborah Wood ('73) is pres-
ently earning her Pharm.D. online
from the University of Colorado,
Boulder, Colorado. She has been
elected to the Academy of Long
Term Care State of Colorado Phar-
macist Society for a two-year term.
Danny Soles ('74) sold his phar-
macy to Eckerd.
Mirta S. Soto ('74) is married
to Manny Soto, CPA and has two
daughters Mirty Soto who is a
first year pharmacy student at UF
and Michelle, a senior at Our Lady
of Laurdes Academy.
Ralph Watson ('75) became a
grandfather for the first time July
15, 2003: Sarah Elenor Grijalua
was born at Dekalb Medical Center
in Decator, Georgia.
Gerald R. Dominey ('78) is an in-
dependent pharmacist with a drug
shop in Pensacola, Florida. He and
his wife, Deana, have an 8-year-
old son, Edward, and a 5-year-old
John Murphy ('79) received the
"Award for Sustained Contribu-
tions to the Literature of Pharmacy
Practice in Health Systems" from
the ASHP Research and Educa-
tion Foundation in December of
2003 at the ASHP meeting in New
Barbara Kelly Ferguson ('83) is
a Clinical Pharmacist at Veteran's
Affairs in Brevard County She has
one son and one daughter and is
living in Melbourne, Florida.
Theresa Wells-Tolle ('88) was
sworn in as the Florida Pharmacy
Association President in June 2003
at the annual convention in Wesley
Chapel. She is the co-owner of
Bay Street Pharmacy in Sebastian,
Florida. She and her husband,
Joe, have two children, Taryn
(age 7) and TJ (age 5). Still avid
Gator fans, the Tolles have season
football tickets and stay with Gail
Wells ('74), Theresa's Aunt in
Susan Durden Beltz ('93) is
Coordinator of the Investigational
Drug Service at Shands UF She
and her husband, Billy, have twin
boys Blake and Bryce who are
almost three years old.
Ted Morton ('93) has been pro-
moted to the associate professor
of pharmacy at the University of
Tennessee College of Pharmacy.
He was also named Health-System
Pharmacist of the Year by the Ten-
nessee society of Health-System
Tony Posser ('94) just celebrated
10 years with Gold Standard
Kevin Ellis ('97) has been married
to Michelle since 1995 and is the
father of two boys Kevin Lee and
Joseph Geber ('95) and Jean
Geber (Finnman '98) welcomed
their first child, Stephanie Kate
Geber into their hearts on Febru-
ary 5, 2003. The Geber's live in
Oviedo where both Joe and Jean
are employed at the Orlando VA
Gary Levin ('90) began working
for Nova Southeastern University
in December of 2003. Gary serves
as a professor and chairman of the
department of pharmacy practice.
Jeana (Everett) Skora ('97) had a
career change in September 2001
when she joined the Air Force.
She has been located at Luke AFB
in Phoenix, AZ and is in charge of
the 7th busiest satellite pharmacy
AF-wide. She also recently married
an AF pilot (Chris) and will be
promoted to deputy commander
of the base pharmacy later this
Katherine (Siar) Andorfer ('03)
was married August 2003 in
Clearwater, Fla., then relocated to
Connecticut to start her job with
Wal-Mart. She and her husband
purchased their first home.
Join friends & alumni at these events...
FPA Gator Reception Gaylord Palms
FSHP Gator Reception Caribe Royale
Institute for Pharmacy Entrepreneurs
September 10- 11
18th Annual COP Alumni Reunion Weekend
Grand Guard Reunion "Class of 1954"
Alumni show Gator spirit at reunion barbecue.
11 th Annual Ken Finger Memorial Day
For more information visit www.cop.ufl.edu/alumni or call 352-265-8034
a Lasting Legacy
By Kelly Markey
When Russ Blaser, class of '76, and
his wife Carol unexpectedly died in a plane
crash two years ago, their sons, Rich and
Mike Blaser, experienced a deep loss that
was difficult to reconcile.
The brothers wanted to honor their par-
ents and find a way to bring meaning from the
tragic loss. Knowing how important pharmacy
education and practice was in their dad's life,
and the obstacles that he had overcome in
reaching his life's goal, they realized that a
scholarship fund was an ideal tribute.
"The best legacy we can leave for them
is to help another pharmacy student who is
in the same situation that my parents were
in when my dad started pharmacy school,"
Rich said. "My brother and I think a lot of the
College of Pharmacy and the pride my dad
took in being a pharmacist"
Russ was first introduced to pharmacy
when he enlisted in the U.S. Army during the
Vietnam war. He dispensed medications and
was promoted to a captain in the infantry. It
was this experience that led him to Gainesville
after leaving the military. He applied repeat-
edlyto UF College of Pharmacy. While waiting
to be accepted to pharmacy school, he and
his wife worked various jobs to support their
two sons. Not one to give up, Russ was ac-
cepted after his third attempt and graduated
at the top in his class. He continued to work
while attending college and still managed to
participate in Florida Blue Key and Student
"Russ was always an optimist. I never
remember seeing him without a smile on his
face. He brought a "can-do" attitude to ev-
erything he touched and it was contagious,"
remembers College of Pharmacy Dean Bill
After graduation, Russ served as a com-
munity pharmacist in the Gainesville area,
consultant pharmacist in psychiatric hospitals
and jails, and as a new drug educator for
doctors. He was president of the Alachua
County Pharmaceutical Association and was
awarded FSHP Pharmacist of Year in 1982.
Each year, the Russ and Carol Blaser
Memorial scholarship will benefit a pharmacy
student, in good academic standing, who has
a family and is in need of financial support.
In the coming years, Rich and Mike hope
to grow the fund to help even more pharmacy
"Our parents never left anything un-
said-they embraced every minute of life,"
Rich added. "The power they had on people
and the way they touched people lives was
unbelievable. They still continue to touch lives
Byron Barnes ('54)
dean emeritus and
trustee of St. Louis
College of Pharmacy
passed away February
24, 2004 in Chester-
field, Missouri. Born
and raised in Illinois,
he enrolled in the
Academy in King
Point, NY. Byron
graduated from St.
Louis College of
Pharmacy with his
bachelor's degree and
received his master's
and doctorate degrees
from the UF College
of Pharmacy. Profes-
sor Barnes joined the
faculty at St. Louis in
1957, and was named
dean in 1970. He
Handbook of Phar-
macy." Very close with
Byron enjoyed giving
talks on "Pink Pills
for Pale People," and
"Old Time Pharmacy."
Among his survivors
include his wife of 55
years, Enid Chandler
Barnes; a daughter,
Julie Burchett; a son,
Jeffrey Barnes; and
Richard H. Beach,
Jr. ('83) a registered
pharmacist in the
Pensacola area for 20
years, passed away
on October 21, 2003.
Rich was a graduate
of Bay High School in
Panama City ('79) and
Gulf Coast Commu-
nity College. Rich is
survived by a partner,
Dwight Brown, his
parents Dick and Pat
Beach, sisters, Jennifer
(Tim) Ramsey and
Beth (George Scott)
Biddle, nieces and
and Katie Landry, and
Mason and Jordan
Biddle; Uncle, John
Steven Bevis ('74)
a pharmacist for
died July 26, 2003
in Daytona Beach.
He was a graduate
of Jefferson County
High, where he was
valedictorian of the
class of 1967. He
was also a graduate
of Emory University
from UF he joined
the Jack Eckerd
Corp., where he
remained for 28 years.
his mother, Lorena
Bevis; a brother
Ken Bevis; and a
niece, Logan Bevis.
John Canova ('54)
of Cross City passed
away in December
of 2003. Born in
raised in Gainesville,
John attended PK.
Research School and
School. He earned
bachelor's degrees in
pharmacy and English
from the UF and did
graduate work at
University of North
Carolina Chapel Hill.
Mr. Canova taught
English at Georgia
Tech and served on
the Board of directors
of the Lentel Corpora-
tion, a family owned
business in Georgia.
('38) passed away
April 24, 2003,
he retired as chief
20 years at the VA
Medical Center at Bay
Pines. Mr. Ferguson
was a past president
of the Florida
Society of Hospital
Pharmacists, a Navy
veteran of World
War II who received
a Purple Heart.
his wife of five years,
"Our parents never
minute of life."
alumni & development news
...In Memorium continued
Claire B.; three sons,
Stephen and Robert; a
daughter, Jean Fergu-
son and a grand-
daughter, R. Lee.
('54) passed away
peacefully on October
24, 2003. Frank was
a pharmacist and
co-owner of Metro-
politan Pharmacy in
Ybor City for more
than 40 years. He
was a past president
cal Association, a
retired Captain of
the United States Air
Force, city council-
man for the City of
Temple Terrace for
10 years, a charter
member Krewe of
the Knights of Sant'
Yago, and a member
of Corpus Christi
Catholic Church. He
is survived by his wife
of 49 years, Evelyn
(Sugie); sons, Samuel
J. and wife Donna,
Frank Sergio, Jr. and
his wife Susan and
Dr. Sam Ferreri
('86) died February
25, 2004, at home
in Merritt Island, FL.
He graduated from
and the University
of Florida College
of Pharmacy in
1986. He worked
as a pharmacist at
Liggett, K-Mart and
cies. He was past
president of Brevard
Association. He also
served as chairman of
the FPA Professional
Affairs Council and
other state level
received the Sydney
from the Florida Phar-
macy Association in
July 2000. Survivors
include his loving
Melissa Hatfield and
Elise Hatfield; his
sisters, Pamela Valdes,
Kristen i-.. i. Heidi
Chavers and Kitty
Lyons; and several
nieces and nephews.
M. Roland Hitt ('53)
died November 8,
2002. He was an avid
boater and fisherman
who loved the water,
and held two world
records for snook
include his wife,
Better (Detter) Hitt;
(Blaise) Maugeri; son,
Stephen (Beth) Hitt;
Deborah Hitt; 14
David Lewis ('53)
died in December
of 2003. He was
Lewis Pharmacy in
Safety Harbor, was
an officer in the
Save Our Suwannee
member of San Juan
Catholic Mission in
include his wife,
Schultz and Vicky
S Lewis, Michelle
West, Elaine Davis
and Mary Lovell; son
David Kirk Lewis; and
Mardis Meyer ('48)
of Austin, Texas
died December 14,
2003. While at the
University of Florida
he was a member
of the Sigma Phi
Kappa Kappa Psi, the
Mortar and Pestle
Society, the University
Band, the University
Orchestra and the
Glee Club. His time
at the University
was interrupted so
he could serve
his country in the
United States Navy.
He had a long and
in the pharmaceutical
field that included
five years with Abbott
ship and operation
of a drug store, and
positions in Miami,
Fort Lauderdale and
culminating in his
eventual retirement as
a Chief of Pharmaceu-
tical Services in North
Broward Hospital in
May 1989. He was
a member of the UF
the Florida Society
of Health System
ciation, the American
Society of Hospital
cal Association and
the Woodmen of the
World. He is survived
by his three daugh-
ters, Melanie Louise
Meyer Turner, and
Melinda Meyer Gross;
Trace Michael Turner
and Marielle Delaney
Turner; his son in law,
Kenneth Gross; two
sisters, Juanita Crews
and Tamea Kelly;
nieces and nephews.
Sarah Ruth Norred
('50 & '54) died
June 6, 2002. She
completed a B.S.
degree at Howard
College and a master's
and Ph.D. degree
at the University of
Florida. She spent
37 years conduct-
ing and managing
research studies in
Corporation of New
Jersey She is survived
by her brother, Robert
Gaines Norred (Pana)
Sarah A. Norred
of New York City;
and a grandnephew,
Norred of Chat-
('54) died March 5,
2004. Mr. Ossenfort
the University of
Florida in 1954 with
a Bachelor of Science
degree in pharmacy
and was a member
of the Phi Kappa Tau
fraternity He was
co-owner of Osceola
Pharmacy, Vero Beach,
for 15 years. He
also was associated
with Broward Drugs
and Gray Drugs,
and later retired
from Eckerd Drugs
in 1994. He was a
volunteer for the
Indian River County
Sheriff's Office and
the Vero Beach
Squad. Survivors are
two sons, Douglas
Scott Ossenfort, of
Vero Beach, and
Kevin Ossenfort, of
Ann Blazei, of San
and one grandson.
('51) died October
26, 2003 in Orlando.
After serving as a US
Marine and earning a
purple heart, Charles
entered the University
of Florida College
of Pharmacy and
received his pharma-
cist license in 1952.
After graduating, he
worked with Albert's
Drug Store, and later
Pharmacy in Kissim-
mee. Mr. Pempey
completed his career
as a pharmacist at
Hospital in 1988. He
was a member of
Masonic Blue Lodge
69, the Scottish
Rite and the Bahia
Shrine. Charles is
survived by his wife
of 42 years, Dorothy
daughter, Sharon R
Miller and his brother
Harry ..-,i. Sr.,
his sister-in-law Betty
Jo (Mrs. Charles)
Abbott, five nieces
and one nephew.
James M. Plaxco,Jr.
('49) died September
11, 2000 in Lexing-
ton, SC. He earned
his Ph.D. in Pharmacy
from the University
of Florida in 1949.
He was a retired
professor of pharmacy
with the University
of South Carolina.
John Riherd ('50)
passed away at his
home in May 2003.
John was a retired
pharmacist and a
U.S. Navy veteran
of World War II. He
was past president
of Volusia County
and Central Florida
served on the Florida
He was a member of
the Daytona Beach
Country Club, Halifax
UF Alumni Asso-
ciation and Calvary
Baptist Church. He
was an avid Gator
fan and enjoyed golf.
his wife of 54 years,
Riherd; a son, John M
Riherd Jr.; daughters
Nancy Wilson and
Susan Riherd; a sister
Frances White and
Sparks, Sr. ('54)
died April 29,
2004 after a short
battle with cancer.
Mr. Sparks was a
life-long resident of
Pensacola. He was a
veteran of the U.S.
Navy, serving during
WWII. He graduated
in 1952, with honors
from Pensacola Junior
College and was
the Class Valedicto-
rian, and from the
University of Florida
in 1954, with honors,
with a BS degree
Sparks was a retired
Hannah's Pharmacy in
1961, and operated
it until he sold it in
1982. In 1981, he
served as president
of the Escambia
Association. He is
survived by his wife
of 57 years, Sue
Eller Sparks; son
Bill Sparks (Cathy);
and Tim Sparks;
Lowery Lee Sparks,
Jr.; eight nieces and
* Odis Burnett '54
* Paul Leonard '64
* George Burnett '60
* Phong Anh Ta '82
W.. m n -
-h -I-. --- V d
Alumni Web Site
Our newi Alummi Web site has all the
information you need to keep up with what's
going on at UF College of Pharmacy You can
find out about upcoming events and planned
reunions See who is on our advisory board,
meet our staff or look at lob opportuni-
ties-you can even post a lob opening We
have useful links to the college, professional
associations and helpful information to those
who want to give back to the college We will
keep you up-to-date with photos and copies of
Visit our Web site, www.cop.ufl.edu/alumni
today, and click on "Stay in Touch We would
love to hear from you and find out your latest
Director of Development and Alumni Affairs
new Director of Development. Building
lasting relationships with the many
College of Pharmacy graduates and supporters and
friends is her main goal. Kelly's prior endeavors before
joining the college include running her own advertising
company and working with the Florida Diabetes Camp.
If you want to know what's going on or how to get
involved with your College of Pharmacy, contact Kelly.
Assistant Director of Development and
megan @cop. ufl.edu
9 IH Megan earned her bachelor's
degree in special events from UF and
later received advanced certification
in the Event Management program at
George Washington University. While
in school, Megan had internships with
Florida House Congressman John Mica, the Ronald
McDonald House, and the Ladies Professional Golf
Association. Megan spent the past year planning our
many college events and meeting alumni. This year,
with new duties as assistant director of development she
looks forward to working with alumni and friends of the
I Laura, who is just starting at the
College of Pharmacy, is a long-time
resident of Gainesville and comes
from a proud Gator legacy Family. She
will be graduating from UF in special
events in August. Laura spent the past
six years working at the UF Alumni Association and
assisted with membership, marketing out outreach events.
In the year ahead, Laura will be planning our alumni
events and is looking forward to working with a new
group of alumni and friends.
alumni & development news
11th Annual Ken Finger Memorial Day
features continuing education & golf
Planned this fall for Oct. 15, the 11 Ith Annual
Ken Finger Memorial Day and CE Program will offer
alumni and friends three hours of continuing education
credits and an afternoon of golf: II .. I by an awards
dinner. This annual event is held in honor of Dr. Finger's
contributions to the University of Florida, where he
served many years as vice president for health affairs,
,.. and to the C .II.,. of Pharmacy where he served as dean
from 1968 to 1978. Promoting the concepts of continu-
...ing education and clinical pharmacy, Dr. Finger helped
establish a curriculum that prepares pharmacists for a
patient-oriented role in health care.
Alumni and area pharmacists are encouraged to
attend a 3-hour live CE course in the morning, which will
include lunch. Taught by UF faculty, the course, "Current
Issues in Pharmacy Practice," will highlight innovative
research and techniques in the areas of diabetes, HIV and mental health.
A golf scramble is scheduled for the afternoon featuring a silent
auction, awards ceremony and steak dinner. For golf sponsorship oppor-
tunities, or to register for golf and/or CE course, contact the C II. ... of
Pharmacy Office of Development and Alumni Affairs at 352-265-8034,
or e-mail Laura at lentz@c i ,,II .. I"
Thanks to our 2003 Ken Finger Memorial Day
and CE Program Sponsors
Platinum Sponsor $5,000
* Barr Laboratories/ Dr. Robert Bell Novartis
Bronze Sponsor $1,000
* Bill's Prescription Center
* Eckerd Corporation
* Purdue Pharma
George t Dorothy Vuturo
Our Alumna in the Spotlight
Theresa Wells-Tolle, R.Ph.,
is the recipient of the 2004
American Pharmacists Association
Good Government Pharmacist of
the Year Award. The award was
presented during the APhA Annual
Meeting and Exposition, in Seattle,
Wash., March 26 30.
The award, established in 1990, recognizes an
individual pharmacist who actively contributes to the
community through his or her voluntary involvement
in the political process. It is presented to an individual
who has raised the profession's awareness of the political
process and worked to achieve legislative objectives that
will improve the ability of pharmacists to provide care
Wells-Tolle, of Grant, Fla., is the president of the
Florida Pharmacy Association and the owner of Bay
Street Pharmacy and Home Health Care in Roseland,
Fla. She has worked to advance the interests of phar-
macists and pharmacy in the Florida legislature and has
made regular trips to Tallahassee to testify on legislation
illI...1 pharmacists and the community. She has also
worked to enhance the visibility of Florida Pharmacists
and their valuable role in patient care in her leader-
ship of the Florida Health Fair. Wells-Tolle received
her Bachelor of Science degree in pharmacy from the
University of Florida C II..-.. of Pharmacy.
1954 class representatives
(l-r) Anita Thompson andJean Plowden
Fifty years after graduating from the College of Pharmacy, the Class of 1954 will celebrate their Grand-
Guard reunion this year Sept. 30 Oct. 2. Alumni from the Class of 1954 are invited back to campus for a
weekend full of events that include a football game and induction ceremony. The College of Pharmacy will
host a tour of its new building on Oct. 1, and a special lunch and with Dean Riffee and other faculty members
has been planned. This will be a great opportunity to catch up with old classmates and recall memories of
As a way to show their appreciation for the opportunities a pharmacy education offered, the class of
1954 is making a special reunion gift. The goal is to assist pharmacy students with partial scholarships by
raising $10,000 to create the "Class of 1954 Scholarship Fund." To commemorate this accomplishment, the
college will place a brick in the courtyard in front of the new pharmacy building.
For more information about Grand Guard, please call Megan in the Development and Alumni Affairs
office at (352) 265-8034, or e-mail email@example.com.
COLLEGE OF PHARMACY
P.O. BOX 100484
GAINESVILLE. FL 32610
PERMrr No. 726