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 Front Cover
 Table of Contents
 Post it
 Distance ed milestone
 UF's first medical class
 Sadove named chief
 (Extra)ordinary people
 Dental digital age
 New clinic
 New Vet Med dean
 Tribble threat
 Cancer crusaders
 Joe Simone
 Oral decongestant replacement
 Research briefs
 Cell cycle
 Women in medicine month
 Ann Harwood-Nuss
 Translational science
 Distinctions
 Candids


UF



The Post
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Permanent Link: http://ufdc.ufl.edu/UF00073869/00028
 Material Information
Title: The Post
Uniform Title: Post (Gainesville, Fla. 2001)
Physical Description: v. : ill. ; 28 cm.
Language: English
Creator: University of Florida -- Health Science Center
University of Florida -- Health Science Center. -- Office of Public Information
Publisher: HSC Office of Public Information
Place of Publication: Gainesville Fla
Creation Date: September 2006
Publication Date: 2001-
Frequency: biweekly
regular
 Subjects
Subjects / Keywords: Health occupations schools -- Periodicals -- Florida   ( lcsh )
Genre: government publication (state, provincial, terriorial, dependent)   ( marcgt )
periodical   ( marcgt )
serial   ( sobekcm )
 Notes
Statement of Responsibility: The University of Florida Health Science Center.
Dates or Sequential Designation: July 27, 2001-
General Note: Title from caption.
 Record Information
Source Institution: University of Florida
Rights Management: All rights reserved by the source institution and holding location.
Resource Identifier: oclc - 47826372
lccn - 2001229452
System ID: UF00073869:00028
 Related Items
Preceded by: Friday evening post (1989)

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Table of Contents
    Front Cover
        Page 1
    Table of Contents
        Page 2
    Post it
        Page 3
    Distance ed milestone
        Page 4
    UF's first medical class
        Page 5
    Sadove named chief
        Page 6
    (Extra)ordinary people
        Page 7
    Dental digital age
        Page 8
    New clinic
        Page 9
    New Vet Med dean
        Page 10
    Tribble threat
        Page 11
    Cancer crusaders
        Page 12
        Page 13
        Page 14
    Joe Simone
        Page 15
    Oral decongestant replacement
        Page 16
    Research briefs
        Page 17
    Cell cycle
        Page 18
    Women in medicine month
        Page 19
    Ann Harwood-Nuss
        Page 20
    Translational science
        Page 21
    Distinctions
        Page 22
        Page 23
    Candids
        Page 24
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UP FRONT


Table of Contents

POST IT
Education I1i : r.n1,:- -il h, il- : In:iI
Administration ..,il: I ,- iI.iia i-Il lii :
(Extra)ordinary people I 1 :1I: 11
Patient care I -it.i l l ,n t..il a.i4 -
Administration Ii- '.I r 1 1I I il-c l
Cover Story i.i r: 1-1 i .ii .1 l:i
Administration I:ll .iiIIn:iri
Research Cell cycle
Library Women in medicine month
Jacksonville -Ann Harwood-Nuss
Administration Translational science
Distinctions
Candids


on the cover
Like their caped comic book counterparts, researchers
at the UF Shands Cancer Center are relentlessly battling
their foe, a disease that claims the lives of millions
every year. Thanks to sheer scientific skill, technological
advances, new facilities and people power, they are
finally gaining ground. The Cancer Center is coming of
age. Cover illustration by Josh Clark.


Fly with nursing
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HSC leads UF to reach record
research funding
The University of Florida received a record
$518.8 million in research funding in
2006, driven by cutting-edge
biomedical research and a growing
relationship with private
industry. The Health Science
Center accounted for just over
half of the university's total,
with its six colleges receiving a HSC Research
record $271 million, up 5.4 $271
percent. \ million
UF passed half a billion
dollars for the first time in the
fiscal year that ended June 30,
thanks in large part to a $13.4 million
increase in funding from the National
Institutes of Health. Overall, federal funding rose to
$324.4 million.
UF's Institute on Aging received two of the largest
NIH awards in 2005-06: $2.7 million to study how




In 1956, when the UF J. Hillis Miller Health Center was
Sounded, an interdisciplinary health science center was
:t.4 still a novel idea. To honor those who turned that novel
idea into a success story, the HSC Office of News &
Communications has produced a magazine to chronicle
the leaders who pushed for the health center to be built
_at UF and the faculty, staff members and students who
have kept the dream alive. For a copy, call 273-5810.









What I did this summer
UF teaches CSI summer camp at local elementary school

As the school year swings into action for students at Oak Hall School, some
just might add a new twist to the traditional "What I did this summer" i
essay. Forget writing about the beach. They're more likely to highlight
tales of buried meat and blood spatter patterns, at least if they report on the
forensic field trip they took in July.
Donna Wielbo, Ph.D., an associate professor in the College of
Pharmacy who teaches UF's forensic DNA and serology master's
program, and David Khey, a UF doctoral candidate in criminology,
teamed up to teach a weeklong crime scene investigation summer camp for children ages 10 to 12.
Jeff Malloy, upper school dean at Oak Hall School in Gainesville, contacted UF last year in search of
faculty who might help develop a new science-related summer experience.
"Oak Hall School works hard to establish cooperative relationships with agencies like the University
of Florida so that we can offer unique, quality summer programs for kids," Malloy said.
Wielbo and Khey brought in a variety of speakers, including an FBI agent, a local law enforcement officer
and a magician who showed the students how pickpockets steal. Activities for the week included forensic
chemistry tests to identify unknown substances, examining buried meat for insects and decay, learning
about the human skeleton and understanding what blood spatter patterns mean to investigators.
Amy Kinsey, a forensic investigator with the Alachua County Sheriff's Office, emphasized to the
students that real-life crime scene investigation is quite different from and not as glamorous as what
they see on television. A 2003 graduate of the UF forensic master's program in toxicology, Kinsey showed
the students her crime scene tool kit and led them in a fingerprint examination activity.
Khey, also a graduate of the UF forensic program in drug chemistry, taught an introductory CSI camp
at Oak Hall last year that this year's camp expanded on. By Linda Homewood


exercise can prevent disability in the elderly and $2.7
million to study rehabilitation techniques designed to
improve walking in the first year after a stroke. Other
large NIH awards included $2.1 million for a
hi. 'jki y laboratory in UF's planned
r urging pathogens facility and $1.6
million to study one of several
incurable forms of blindness that
Other UF Research afflict about 200,000 Americans.
$247 "It's a testimony to the quality
of our faculty that UF's NIH
ill funding continues to increase at a
time when the agency's budget has
leveled off and the competition for
funding has increased
considerably," said Win Phillips,
I i's vice president for research.
UF's industry funding rose from $49.7
million in 2005 to $62.4 million last year.
Among the largest industry grants was $1.5 million to
conduct clinical trials on new HIV treatments and
$1.5 million to study the use of lasers to repair
macular degeneration that leads to blindness.








Manage stress one

step at a time with


The start of another academic year and
all the stress that comes with it is the
perfect time to make a new commitment
to physical activity, a scientifically
proven stress-buster. Gators on the Go is
a free Web-based program that allows
participants to walk, swim, bike, dance,
run or even garden their way to a U.S.
or European city of their choice.
Participants choose a goal distance and
then log their "mileage" from different
activities as they "travel" to their
destination.
Sponsored by the Healthy Gators
2010 coalition and the College of Health
and Human Performance, Gators on the
Go will kick off from 11 a.m. to 2 p.m.
Sept. 26, at the Reitz Union Colonnade.
At 11:30 a.m., UF's first lady Chris
Machen, chair of Healthy Gators 2010,
will lead a 1-mile walk around campus,
followed by a speech at noon.
Registration began Sept. 1 at www.
healtygators.hhp.ufl.edu. For more info,
contact Cher Harris at ctharris@hhp.
ufl.edu or 392-0578 ext. 1279.


Visit us online @ http://news.healthul.edu/ for the latest news and HSC events. I


/
I





EDUCATION


Dental Diversity
The University of Florida College
of Dentistry has been ranked the
No. 3 producer of Hispanic
dentistry first professionals out of
56 dental institutions in the nation
by Diverse: Issues in Higher
Education magazine.
The college was ranked No. 15
for overall minority dental
graduates, No. 12 for African-
American dental graduates and No.
23 for Asian-American dental first
professionals.
The Diverse rankings use U.S.
Department of Education data for
the 2005-06 academic year to rank
the top 100 minority graduate
degree-producing American
institutions in the categories of
master's, doctoral and first
professional degrees awarded.
Groups designated as minority
include African Americans, Asian
Americans, Hispanics and Native
Americans but do not include
foreign minority students.
UF was ranked No. 9 for total
minority doctorate degrees
conferred in the health sciences
and tied for No. 26 for Hispanic
medicine first professionals.
For more information on UF's
minority graduate and doctoral
degree rankings, visit www.
diverseeducation.com.
-Lindy McCollum-Brounley


Attending the College of Pharmacy August commencement are (from left) WPPD clinical faculty members
Nancy Kazarian and Linda Rolston, who also were among the first graduates of the program in 1997; 1,000th
graduate Teresa Watkins, (class of 2006); and Sven Normann, associate dean of distance education.


A big score for UF in building a


Gator Nation of pharmacists

By Linda Homewood


With football season in full swing, the
University of Florida College of Pharmacy is
kicking off fall semester with one big score for
the Gator Nation: 1,000. That's the number of working
pharmacists who have earned professional degrees
through UF distance education program to become
official Gators.
In August, Lt. Cmdr. Teresa Watkins, a pharmacist at
the U.S. Public Health Service in Washington, D.C.,
traveled to Gainesville to claim her academic title and her
place as the college's 1,000th graduate of the UF Working
Professional Pharm.D. program. Her by-chance ranking
was secondary to her personal achievement of graduating
with top honors and receiving the college's Outstanding
Leadership award.
Balancing the academic demands of the UF program
with clinical assessments at the National Institutes of
Health and her work as the designated official for two
Food and Drug Administration advisory committees
proved challenging.
"The program was incredibly rigorous. I continue to be
amazed by the quality of the faculty as well as the caliber
of student the program attracts," Watkins said.
Though not as commonly known as the Army, Navy, Air
Force or Marines, the PHS is a branch of service quite
familiar to William H. Riffee, Ph.D., dean of the College of
Pharmacy, who also served there as a young pharmacist.
While offering "congratulations from one officer to


another," Riffee said the WPPD students were among the
most highly motivated learners he has encountered.
"These students put their education to use the day after
mastering the content, raising the level of pharmacy
practice immediately in their workplace," Riffee said.
The need for the WPPD program began in the mid-
'90s when pharmacy degree programs nationally began
phasing out baccalaureate degrees and instead offering
the Doctor of Pharmacy Pharm.D. degree as a first
professional degree.
"For many pharmacists, taking time away from their
careers to re-enroll in a pharmacy program was not an
option and that's why the distance learning program was
born," said Sven Normann, associate dean of distance
education.
In 1996, the WPPD program formed an early
partnership with Compass Knowledge Group Inc., a
Florida-based higher education services company,
Normann said. Compass provided services in marketing,
instructional design, student recruitment and retention,
and increasing the national and international student
enrollment from 40 to 600 by 2005.
For Watkins, the doctor of pharmacy degree opens new
doors, including opportunity for a promotion to
commander next year.
"With my new credentials, I'm even thinking about
possibly returning to a clinical career in the future after
my military service," Watkins said. O


404 1 *k U Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.





EDUCATION


United by a





By April Frawley Birdwell



UF's first medical class


paved the way for

future medical students


Students from UF's first medical class mingle with faculty members
and founding dean George T. Harrell at a student reception.


The only thing Jean Bennett, M.D., ever wanted to
be was a doctor.
Mark Barrow, M.D., wasn't really sure what he wanted to do with his life
until he met George T. Harrell, M.D., in Grove Hall one day.
Other students in the UF College of Medicine's first class spent years in other careers
before deciding to start medical school. Some of them, with balding heads and families,
were older than their newly minted professors.
But on Sept. 17, 1956, all 47 students who started classes in the new College of
Medicine were united, by a shared dream to become doctors and by a shared role as
trailblazers for the more than 4,000 medical students who would follow them over the
next 50 years.
"There was an attitude of 'all for one and one for all,'" said Bennett, now a retired
pediatrician in Clearwater.
With no older medical students to guide them or let them know it was all right to take
breaks, the first students worked intensely, often staying in their individual study
cubicles until 10 or 11 every night for the first year. The cubicles, the brainchild of
founding Dean Harrell, had enough space for a desk and microscope, a place to hang a
white coat and room to stack books. If they weren't in their cubicles, which Harrell had
dubbed "thinking offices," they were in the lab or the library, Barrow said.
At a time when American medical schools were still mostly filled with white male
students, the first class also was uniquely
diverse. There were three women, including
Bennett, as well as Hispanic and Asian
students in the first class.
"(Harrell) championed the idea of student
diversity before it became an educational
buzzword," Bennett said. "The playing field
was level. Everyone had an equal
opportunity."
And after the first year, they eased up a
little and began to have some fun. When
they had time, which wasn't often, students
attended football games, went on dates, hung
out at the few places there were around town
then and threw parties. Parties presented
their own challenge in 1950s Gainesville,
though, Barrow said.
"The county was dry, so if you had a party
you had to make a run to Ruby's in Putnam
County or Henry's in Marion County,"
Barrow said. "We made something with
grape juice and vodka. We called it 'Purple
Passion.'"
The hospital had yet to be built when the
students began classes in 1956 but was ready
when they began their clinical rotations two
years later. But it took awhile for the teaching
hospital, now Shands at UF, to become the
bustling place it is today.
"We had like three patients a week and we
were scrounging to get those sometimes," said Jim Free, M.D., a retired nephrologist
and a graduate of the first class. "But I feel like we learned more from those few patients
than we could have learned from a thousand patients. We were expected to know
everything in detail."
By the time they graduated in 1960, only 40 of the original 47 students remained, but
the group was tight-knit, members of the class say.
"We all knew the dean," Free said. "We all knew everybody. It was like a small
family. We had a camaraderie among ourselves that was unique." 0


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. I. 0 5





ADMINISTRATION


The new face of aesthetic medicine


Sadove named chief



By Melanie Fridl Ross
Richard Sadove, M.D., has been named chief of the aesthetic medicine
service, part of the department of surgery's division of plastic and
reconstructive surgery at the University of Florida College of Medicine.
Sadove spent the past 13 years in private cosmetic practice in Tel Aviv. A
recipient of a J. William Fulbright Foreign Scholarship, he helped to establish a
department of pediatric plastic surgery at Tel Aviv University, where he was a
visiting associate professor. Prior to that he was an associate professor of plastic
surgery at the University of Kentucky Chandler Medical Center and chief of the
plastic surgery department at Lexington Veterans Hospital.
"The division here is in a period of rebuilding and growth," said Sadove, whose
main areas of interest include minimally invasive techniques for facial
rejuvenation and breast reconstruction for cancer patients. "I'm impressed by the
potential here and the people here."
His arrival coincides with the construction of an enhanced facility for cosmetic
surgery services, slated to open soon off Newberry Road in the Park Avenue
medical complex. It will offer discreet consultation areas and improved computer
technology, including digital imaging depicting post-treatment results likely to
be achieved.
While in Israel, Sadove gained years of experience working with cohesive gel
anatomic breast implants, a type not yet available in the United States for
commercial use. UF is currently participating in an FDA study of the implants.
In addition, he had access to filler materials for the treatment of wrinkles that
were only recently approved for use in this country.
A Chicago native, he received his medical degree from Rush Medical College.
He completed his general surgery residency at Rush-Presbyterian-St. Luke's
Medical Center, where he was chief resident, and his plastic and reconstructive
surgery residency and fellowship at the Eastern Virginia Graduate School of
Medicine. He is board certified in plastic surgery.


He is a fellow of the American College of Surgeons and a member of numerous
professional societies, including the American Society of Plastic and
Reconstructive Surgeons, the International Society of Aesthetic Plastic Surgery
and the European Association of Plastic Surgeons. He lectures internationally on
subjects in the field of cosmetic surgery.
"There is a huge demand for cosmetic surgery on the part of society," said
Sadove, adding that he is looking forward to helping to train residents in quality
cosmetic surgery techniques. "The need is there in society, and society demands
doctors get excellent training in cosmetic surgery. I think the institution, in
having this vision, is responsive to that." Q


PHHP announces administrative changes


The UF board of trustees recently
approved three new initiatives in the
College of Public Health and Health
Professions.
These initiatives include the
establishment of the department of
epidemiology and biostatistics, led by
Elena Andresen, Ph.D. In addition, the
department of rehabilitation counseling,
chaired by Barbara Curbow, Ph.D., has
changed its name to the department of
behavioral science and community


health to reflect the addition of public
health divisions in environmental
health and social and behavioral
sciences to the existing program in
rehabilitation counseling.
Lastly, a School of Health Professions
was created within the college to
organize the disciplines focused on
disability and rehabilitation.
The establishment of the School of
Health Professions recognizes the
college's 50-year commitment to its


programs in rehabilitation, chronic
illness or injury, and health policy, said
Robert Frank, Ph.D., dean of the
College of Public Health and Health
Professions.
"While we are excited about the
opportunities and challenges for the
college in public health, we want to
remember that our heritage is in the
health professions. This is a symbolic
and practical step for the college," he
said. Jill Pease


606 1 *k U Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.















































The Cat in the Hat, a.k.a. Robert Pelaia, pretends tc be a talk show host and introduces some of the inhabitants of the Jungle of Nool including
Lazy Mayzie LaBird and the bird girls to the audience during Theatre Jacksonville's recent production of "Seussical The Musical."


n his role as attorney for UF's Health Science Center in
Jacksonville, Robert Pelaia wears many hats. He conducts research,
gathers facts, analyzes audiences, shares information, encourages
dialogue and focuses on the task at hand.
As an actor, Pelaia uses the same skills but plays multiple roles -
both human and animal and wears much wilder hats. In fact, the
most recent was the oversized, red-and-white-striped version the Cat in
the Hat sports.
Pelaia grew up in Edison, N.J., and his parents often took him to
Manhattan to see Broadway plays.
'Shenandoah,' 'Annie' and 'Dracula' were the first shows I saw," he
said. "Then in grade school we wrote our own shows and put them on
for the entire school. I did a few high school productions, some spring
musical shows and a couple of community theater plays but stopped
acting when I started college."
After earning a bachelor's degree in French and communications
from the State University of New York at New Paltz, Pelaia worked in
marketing. Even though he wasn't on stage, his office was on the 70th
floor of the Empire State Building just eight blocks from Broadway.
Six years into his marketing career, he started law school at Seton
Hall University.
"I was interested in health law policy," he said, "and completing an
externship at a New Jersey hospital cemented that specialty for me."
After earning his J.D., Pelaia went to work for a private health law
firm in Washington, D.C.
In 1998 the same year Gainesville was rated one of the nation's best
cities to live in Robert joined the Office of the Vice President and
General Counsel as an associate general counsel at the UF Health
Science Center in Gainesville. In May 2000, he became the attorney for
the UF Health Science Center in Jacksonville.
Robert found his theatrical home at Theatre Jacksonville, Florida's
longest-running community theatre. He serves on the theatre's


repertory committee and has performed in several productions as
Dale Harding in Kesey's "One Flew Over the Cuckoo's Nest," as one of
a "cast of thousands" in Coen and Crane's "Epic Proportions," as
Snoopy in "You're a Good Man Charlie Brown" and most recently as
the Cat in the Hat in "Seussical The Musical."
"I do it because it's an opportunity to get your creative juices flowing
and do something that makes you happy," he said. "It fans the flames
inside of you for something that you want to be doing."
Pelaia, a.k.a. the Cat in the Hat, particularly enjoyed Theatre
Jacksonville's most recent production, "Seussical the Musical," because
it attracted all ages.
"The thing that was just wonderful about this show was the whole
family atmosphere," he said. "This was the first time Theatre
Jacksonville offered a 'child's ticket' price, and we broke all previous
ticket sales records in the theatre's history.
"The other fun part of doing "Seussical" is that my kids could come
see it," Pelaia added.
He and his wife, Judi, have three children 12-year-old son Griffin
and 9-year-old twin daughters Tess and Greer.
"All of our children have done theatre at the Theatre of Youth
Program at the Jewish Community Alliance and attended summer
theatre camp at Theatre Jacksonville," he said. "I brought one child to
each 'Seussical' rehearsal, and Griffin helped backstage."
A couple of times Cat Pelaia had to dash off stage right, run through
the lobby at the back of the theater and rush down a hallway for a stage-
left entrance. "In the lobby I sprinted past a dad-reprimanding-son
situation and overheard the dad say, 'Look, here's the Cat in the Hat
right now! Do you want him to see you act this way?'"
Pelaia had no idea the Cat had so much clout.
"There were tons of kids in the audience, and I had no idea what a
popular and recognizable character the Cat in the Hat is," Pelaia said.
"They even lined up for the Cat's autograph after the show!" 0


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. *- 0 7





PATIENT CARE


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Putting down roots


By Lindy Brounley


Dr. Emma Lewis, an assistant professor of oral and maxillofacial
surgery, watches the on-screen progress of an implant surgery
as surgical dental assistant Deanna Hardee assists and Dr. Will
Martin observes. The implant navigation system combines CT
imaging, software and motion tracking technology (note the
sensors on the hand piece and patient tracker at left) to monitor
the surgical drill's exact position, angle and depth in real time.


3D imaging keeps computerized implant navigation on course


When it comes to im-
plant dentistry, many
practitioners are just
now cutting their teeth in this
young field, which relies on the
latest prosthodontic and surgical

techniques.

Now, thanks to technological advances, they are
finding the learning curve is shorter than ever.
Planning, placing and restoring dental implants
requires enormous expertise, manual dexterity
and creative thinking. And dental implant teams
have been breaking new ground in territory where
others fear to tread-though it's a landscape that


is becoming increasingly easy to navigate.
"I think the trends in dentistry are really
enhanced through access to three-dimensional
imagery," said William C. Martin, D.M.D.,
clinical director of UF's Center for Implant
Dentistry. "Implant navigation and guidance offer
the ability to merge the 3D information from a CT
scan into the ... planning frame of the therapy,
allowing the implant surgeon to achieve the ideal
positioning of the implant with extreme
accuracy."
Martin should know. UF was the first
university in the United States to receive the IGI
Implant Navigation System, donated in the fall of
2004 by the Israeli company DenX. DenX also
partnered with Straumann US to arrange for a
cone beam CT unit to be installed in the college's
radiology suite this January, helping to bolster the


center's clinical treatment and research
enterprise.
The two technologies represent the state-of-the-
art in implant surgery, and they're keeping UF's
Center for Implant Dentistry close to its trend-
setting roots. Established in 1999 through
collaboration with Straumann AG, the
International Team for Oral Implantology and the
UF College of Dentistry, the center was the first of
its kind in the world designed to be an
interdisciplinary ground zero for the creative
exploration of dental implant surgery, research
and education.
"The computer-aided implant navigation
system affords us the ability to treat those more
complex patients that may have anatomical
variances that make surgery difficult, whether a
nerve is really close to where you want to put the


88 1 *k Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.


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implant or whether you need to negotiate around
a sinus or another tooth," Martin said.
The IGI system software helps the implant
team create a treatment plan using 3D CT
images, and then facilitates real-time navigation
during surgery, greatly enhancing the accuracy
of implant placement, often without having to
retract the gum tissue away from the bone.
"In certain situations, the system affords us
the ability to make a small punch incision in the
gum tissue prior to placing the implant," Martin
said. "In previous situations, we would have to
broadly reflect the gum tissue to assist in
visualization of the bone."
This dramatic decrease in surgical trauma to
the patient's soft tissue makes for a faster, less
painful recovery.
That doesn't mean all patients are candidates
for computer-aided navigation, nor are all
dentists candidates to become implant surgeons.
"This technology and all other technology
that utilizes computers to aid in providing care is
not to be misinterpreted with technology that
will allow just anyone to do the procedures,"
Martin said. "When you're dealing with dental
implants, you're dealing with a surgical situation
with the potential for medical complications or
emergencies, so the clinician behind the
technology should be formally trained in
implant surgery."
Conversely, the technology may not be a good
fit for all implant surgeons. Martin said the
popularity of computer-aided implant navigation
and other technologies will depend not only on a
surgeon's ability to access 3D imaging equipment
but also to his or her comfort level with using
new technologies.
"What you're going to see is our younger
generation, the PlayStation generation, walking
right into it with no problem," Martin said. "Our
future dentists three to five years down the road,
and I think it will be that soon, will have easy
access to three-dimensional imaging much more
than we do today.
"They'll also be far more comfortable and
familiar with using digital technology in general.
For them, it'll be a piece of cake," he said. O


Dr. Anne-Marie Slinger, a developmental-behavioral pediatrician in the UF College of Medicine, co-
developed the School Problems Clinic, a multidisciplinary clinic that will allow clinicians to catch
underlying problems that stymie children in class.



New clinic helps students

make the grade


By April Frawley Birdwell
One-fifth of school-age children struggle to make gains in the classroom, and uncovering
what keeps some kids from achieving success in school is a problem that stumps teachers,
parents and physicians.
That's why faculty members from three UF colleges have teamed to form the School Problems
Clinic, a multidisciplinary clinic they hope will help families solve the puzzle of why some children
struggle in school.
About half of children with achievement problems have a learning disability or attention-deficit
hyperactivity disorder, but for other children the causes are far more subtle, said Anne-Marie
Slinger, M.D., a UF developmental-behavioral pediatrician in the College of Medicine who co-
developed the clinic.
Underlying health problems such as seizures, anemia or allergies can affect a child's ability to learn,
as can sleep troubles, hearing loss, vision problems and socio-emotional problems, Slinger said.
Linking pediatricians from the College of Medicine, psychologists and audiologists from the
College of Public Health and Health Professions and speech-language pathologists and audiologists
from the College of Liberal Arts and Sciences will allow clinicians to notice factors that often go
overlooked, Slinger said.
"Rather than simply looking at surface symptoms, we're looking for the underlying reasons for a
student's achievement problem," she said.
The clinic will provide comprehensive evaluations to find the root of a child's academic problems.
This process may involve vision and hearing screening, as well as neurodevelopmental,
neuropsychological, speech, language and audiological testing.
Children are motivated when they feel capable of achieving success, but if they continue to fail
despite their hard work, they often stop trying, Slinger said. If learning problems are not identified
early, children sometimes develop secondary emotional problems as well, Slinger said.
"Without appropriate support and intervention to help them develop deficient skills, children
who struggle in school are at risk of school failure and dropping out," she says. "Therefore, one of
our goals is to intervene early."
Starting the clinic had been a longtime goal for Slinger and former faculty member Richard
Frye, M.D. The goal was realized when the Children's Miracle Network granted them program
development funds to establish the clinic's infrastructure.
Eventually, faculty members say they would like to expand the clinic to offer comprehensive
treatments for learning disorders and associated problems in addition to evaluations, Slinger said.
But for now, helping families put all of the pieces together is a good first step, she says.
For more information, call 846-2182 or go to www.spc.peds.ufl.edu. 0


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. | 0 9





ADMINISTRATION


New veterinary dean sets sights high



By Sarah Carey


already an upper-tier school,
the UF College of Veterinary

Medicine is poised to join

the elite ranks, says incoming dean

Glen F. Hoffsis, D.V.M.

"We will capitalize on our clinical science, research and
student program strengths," said Hoffsis, who will officially
start his new position Oct. 1, becoming the college's fifth


senior vice president for health affairs, and Jimmy
Cheek, Ph.D, senior vice president for agriculture and
natural resources.
Hoffsis quickly flew to Gainesville to address faculty
and staff, saying he "wanted to personally accept the
position." He called UF's veterinary college "a top-tier
school of veterinary medicine," but said he knew many
here were interested in advancing to the top five in the
country.
"I like that, because it shows a desire to advance
beyond the status quo," Hoffsis said. "I have the sense
that this College of Veterinary Medicine is integral to

























,4








... i,' ;;


Dr. Glen Hoffsis and his wife, Lana, visit with well-wishers at the UF College of Veterinary Medicine


after the announcement of his appointment as dean.


permanent dean. "With a strong outreach program and
fundraising effort, I expect to see robust growth."
Recognized for leading the College of Veterinary
Medicine at The Ohio State University to national
prominence, Hoffsis was chosen to lead at UF after a
nationwide search, according to Douglas Barrett, M.D.,


the advancement of the University of Florida. I also have
the sense that as the college advances, and advances UF
along with it, there will be reciprocal support."
Hoffsis noted Florida's strong agricultural, equine
and small animal industry constituencies are valuable
resources for UF's veterinary college and would continue


to be assets. Furthermore, he mentioned the small
animal hospital fundraising effort and noted the
emerging pathogens initiative as important to the
college's progress.
"Manyagents used by terrorists are animal pathogens,"
he said. "More people are becoming concerned about
the bird flu. These are avenues for us to demonstrate
what we have to offer and to make a contribution."
The OSU College of Veterinary Medicine progressed
from a limited accreditation status with the American
Veterinary Medical Association during Hoffsis' term as
dean to a ranking of sixth among veterinary medical
schools in the country by U.S. News & World Report.
"During his tenure as dean at Ohio State University,
Dr. Hoffsis oversaw a remarkable expansion in the
college's research and academic output, expanded its
clinical teaching hospital and moved the college forward
in peer rankings to become one of the best in the
country," Barrett said. "He knows how to build and
grow a college, and he's extraordinarily enthusiastic
about this opportunity."
After a long career at OSU, including 11 years as
dean, Hoffsis joined lams, a Procter & Gamble company,
as associate director of veterinary services. As such, he
has led a group that implements academic programs in
colleges of veterinary medicine in the United States
and overseas.
"At this point, I'm looking forward to combining my
experience in academia with my new perspectives gained
in the corporate world and putting them to good use at
the University of Florida," Hoffsis said. "I am honored to
have the opportunity to lead the fine College of Veterinary
Medicine at UF to a new level of excellence."
Hoffsis is an established and visible leader among
veterinary medical school deans, having served as a
former president of the Association of American
Veterinary Medical Colleges, UF administrators said.
Furthermore, he has also been president of the American
Association of Bovine Practitioners and chairman of the
Food and Drug Administration's veterinary medicine
advisory committee.
"Dr. Hoffsis brings an incredible amount of

experience and commitment to this position," said Jimmy
Cheek, Ph.D., UF senior vice president for agriculture
S and natural resources. "He's done everything from
researching cattle diseases and directing a veterinary
teaching hospital to significantlyexpanding development
efforts and leading the veterinary services division of a
major corporation."
Hoffsis received his veterinary medical degree from
Ohio State in 1966 and completed an internship in large
animal medicine at Colorado State University in 1967. He
is a board-certified veterinary internist. He replaces former
dean Joseph DiPietro, D.V.M., who served nine years in
the job and left in February to become vice president for
agriculture at the University of Tennessee. 0


101 Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.











Tribble




threat


New chief of cardiothoracic

surgery is a skilled surgeon,

administrator and teacher


By Melanie Fridl Ross
Curtis G. Tribble, M.D., has been named
vice chairman of the department of
surgery and chief of its division of cardio-
thoracic surgery.
Tribble is a graduate of the Vanderbilt University School of Medicine and
completed postdoctoral training in general, thoracic and cardiovascular
surgery at the University of Virginia, where he subsequently served on the
faculty for 19 years.
He is credited with helping to start UVA's heart transplant program and
served as its surgical director for the past 18 years. In 1991, he also helped
perform the first lung transplant in the state of Virginia, launching the
university's lung transplant program. In addition, he ran the general
surgery residency for a decade and was the longtime director of the
department's student clerkship.
Tribble has won every available teaching award at UVA, some more
than once.
"It was a special treat for me to walk from a techniques lab with an
idealistic new third-year medical student fresh out of the basic sciences in
the morning and in the afternoon go operate with the thoracic surgical
residents," Tribble said. "In essence, I was encompassing the entire
spectrum of teaching in surgery, from the youngest and most
inexperienced med students to the most senior and experienced surgical
residents.
"I have always gotten energy back from people who are learning, and
that has always been part of my focus," he added. "It has been a very
symbiotic mission, and not one that I do out of feeling an onerous burden
or obligation but because I really have fun with it. To me it's viscerally
satisfying to see people progress in what they're doing, and I have not lost
my enjoyment of that."
Tribble said he intends to emphasize education here at UF as well,
essentially making thoracic surgery training at UF "second to none."
"Although this division has had a good reputation for education,
obviously that's an interest of mine, and I want to be sure we in the
College of Medicine and the department of surgery are really immersed
with interactions with students and residents of all levels," he said. "I'm
really committed to having that happen."
In addition, he said he is devoted to fostering academic productivity and
superior patient care. Initial plans call for recruiting an additional
surgeon whose primary focus is in general thoracic surgery, thoracic
surgical oncology and lung and esophageal cancer.


"I really want to focus on how our patients experience our care," Tribble
said. "I think people around the world have spent a fair amount of time
looking at the technical side of what is done in a division like this, and
have not spent a lot of time thinking about the patient as an integral part
of this."
Tribble, who is board certified in surgery and thoracic surgery, has
published more than 200 papers in refereed journals. His National
Institutes of Health-funded research efforts have largely focused on organ
preservation after lung transplantation. Other projects have analyzed how
children fare after receiving transplanted lung tissue from adults versus
from other children, and studies of whether adult lung tissue can be
stimulated to grow in the presence of certain growth factors. He also has
been involved in developing the next generation of ventricular assist
devices, work that he will continue at UF.
William Cance, chairman of the department of surgery, praised college
administrators and Shands at UF officials for recognizing the importance
of supporting the cardiothoracic program through Tribble's recruitment.
"It's a credit to the hospital; Shands' contributions represent a
commitment to the future of cardiovascular services, not only working
with the college to recruit the finest people but also a true commitment to
state-of-the-art technology, to be leaders in the technological advances
we're seeing in the cardiac surgical realm," Cance said. O


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. I U 1 0 11






-KUN YOT


fTORY BY MELANIE FRID
pHOTOS BY SARAH Kll



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REPRODUCING. CAN THIS NEOPLATIC
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i j 7 shortly after cell biologist Stephen Sugrue arrived on
campus 10 years ago, he set out to do an experiment
that involved rapidly multiplying cells in a lab dish,
(?A b 7 ~ J(? LI hcn abruptly halting their growth.
'topping the cells in their tracks required a chemical he
a umed would be within easy reach on his lab shelf. But finding
ii required a bit of a scientific scavenger hunt, one that today
i > presents for him the giant leaps the UF Shands Cancer Center
haj. made since then.
"I came down from Harvard from the cell biology department,"
!called Sugrue, Ph.D., now associate director of basic science
I--i the Cancer Center and chairman of the medical school's
department of anatomy and cell biology. "There every lab would
have such reagents. Here it took me two or three days to find
somebody who had a reagent to do a cell-cycle block. It was like
borrowing a cup of sugar!"
In those days, researchers studying how cancer cells
proliferate and spread were virtually nonexistent at UF, as was
National Cancer Institute funding-a couple of grants totaled a
paltry $500,000.
"We started from ground zero and we needed to build," he
said. "The Cancer Center existed on paper but really didn't have
any substance to it."
Today the landscape looks far different. There is no shortage
of the reagents Sugrue needed a decade ago. Furthermore, a
'/.. brand-new $85 million, 280,000-square-foot Cancer & Genetics
SResearch Complex has been added to house those bottles and
the expanding number of people who use them.
., i The Cancer Center has come alive.
That's in large part thanks to a cadre of scientists who have
blt marshaled their forces in the fight against cancer. Like their
Escaped comic book counterparts, these researchers rely on
1 strength and speed to battle their foe, a disease that claims the
lives of millions every year. No superhuman abilities here-just
plain old scientific skill, technology and sheer people power to
propel them forward.
Money also has helped. The overall institutional investment in
cancer in the past decade has been simply astounding-in excess
of $600 million. Consider, too, the cancer extramural research
base, which has grown from $3.7 million to $24.6 million in just
seven years. And for the first time in the institution's history,
administrators say, UF has in place fundamental bench research
in cancer that will yield advances at the patient's bedside. To
further that effort, a critical mass of scientists has been assembled,
bolstered by a flood of new faculty recruits: In the past year alone,
25 cancer researchers have come on board.


121 *ke Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.







NEUROIURGERY
CHAIRMAN WILLIAM
FRIEDMAN, M.D, EXPLAINS A NEW
MACHINE FOR NONINVA$IVE, IMAGE-GUIDED
S RADIO SURGERY CALLED THE TRILOGY TX MEDICAL
S LINEAR ACCELERATOR, DEVELOPED BY VARIANT MEDICAL
. SYSTEMS OF pALOALTO, CALIF.. USING TECHNOLOGY
PERFECTED AT UF. THE TREATMENT INVOLVES DELIVERING
PRECISELY FOCUSED. HIGH-ENERGY RADIATION TO A
PATIENT IN A SINGLE TREATMENT SEIION AT HAND AT UF
MEDICAL CENTER. THE INTENT Ia TO DESTROY
MALIGNAT OR NONMALIGNANT TUMORS OR TO MAKE
OTHER MEDICAL REPAIRS THAT CANNOT BE
ADDRESSED BY CONVENTIONAL SURGERY.


The list goes on: Last month, UF's Proton Therapy
Institute-one of only five in the nation-treated its first
patient. And by 2009, the Shands at UF Cancer Hospital
will have sprung up along Southwest Archer Road.
"We expect to be major contributors to ending the long-
fought war on cancer," said W. Stratford May, M.D., Ph.D.,
Cancer Center director. "We plan to grow our cancer
operation through research and clinical trials. That's what
I envision the Cancer Center being able to do-to provide
the infrastructure, the support, the colleagues and all of
the backup needed to develop a new therapy and bring it
into testing in the clinical arena for the potential benefit
of patients. That's our job."

ABLE TO BUILD TALL BUILDINGS
Building up the research effort to support the overall
cancer initiative has been a key thrust for UF scientists.
"When I arrived here, there were pockets of excellence
in both laboratory science as well as clinical investigation
but no coordinated effort, and we didn't have any synergies
between one individual and another individual's efforts,"
said John Wingard, M.D., the Cancer Center's deputy
director for the Gainesville campus. "When the institution
made a decision to recruit a new Cancer Center director,
Dr. May, and to put resources behind coordinating both
the research and the clinical efforts, we for the first time
had the opportunity to blend those in new ways that made


the effort more than any one individual's efforts. Over the
last five years or so, we've spent an enormous amount of
time recruiting new investigators to our campus with a
cancer focus and also encouraging individuals in other
disciplines that were tangential to cancer to try to turn
that focus more toward the cancer research effort.
"And of course this big push over the last few years has
been enormously facilitated by the new (Cancer &
Genetics) research building, where these individuals who
had been scattered across campus now are on a day-to-day
basis rubbing elbows and talking about common research
problems or technical issues, so they can draw on each
other's ideas," he added.
Information gleaned in the lab can then be used to
identify new targets for novel therapies that can be tested
clinically. Researchers in pharmacology and therapeutics,
for example, have done groundbreaking work on an
enzyme that is active in stimulating cancer cell growth,
May said, opening new avenues for drug development.
As science changes, research opportunities expand,
too, often in unexpected ways. The Cancer Center is
pouring resources into epigenetics, a promising field
involving the molecules that package a cell's genome.
Much of that work will go on in the new building, home
to half the cancer-focused researchers on campus. And
while it's a focal point, "our bright new shining star on
campus for cancer and genetics research," Sugrue said,


the cancer research initiative is much bigger than that.
Researchers still populate the Academic Research and
Medical Science buildings, offices within the College of
Dentistry and a multitude of departments on main
campus.
Meanwhile, UF researchers continue to pioneer new
treatments. In July, physicians treated eight patients with
the Trilogy Tx medical linear accelerator. They were the
first ever to receive this form of noninvasive, image-
guided radiosurgery, which targets tumors with precisely
focused radiation.
Other notable initiatives include the planned cancer
hospital facility, which will provide the latest technology
and high-quality care. Clinicians now scattered throughout
the existing hospital system will be able to work in an
interdisciplinary fashion more easily, Wingard said.
"Cancer affects so many of us personally as well as
professionally," said Shands HealthCare CEO Tim
Goldfarb. "The Shands at UF Cancer Hospital will allow
us to blend the science of medicine with the art of healing
in a specially designed space."
And last month, a Cocoa Beach man with prostate
cancer became the first patient to undergo treatment at
the new 98,000-square-foot, $125 million UF Proton
Therapy Institute, the first time this advanced form of
radiation therapy has been offered in the Southeast. The
therapy has a high rate of success in curing prostate cancer


CONTINUED ON PAGE 14


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. I U. 0 13


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and malignancies of the brain, lung, head and
neck, eye, cervix, gastrointestinal tract, bones
and soft tissues, with minimal side effects.
"We are determined to offer patients in Florida
and the Southeast the best possible treatment
options, whether it be proton therapy,
conventional radiation therapy, surgery or
chemotherapy," said Nancy Mendenhall, the
institute's medical director. "We do believe that
protons will occupy a very important place among
the armamentarium of cancer weapons. We are
also poised to become a center for both clinical
and basic research that will increase our
understanding of basic disease processes and
improve cancer treatments."

CANCER CRUSADERS
The development of five cancer-focused research
programs has helped fuel recruiting in cell
signaling and apoptosis; cancer genetics,
epigenetics and tumor virology; stem cells,
vasculogenesis and cancer; experimental
therapeutics; and cancer prevention, control and
population research.
Since 1999, the university has hired 71 new
faculty members whose work addresses cancer, 51
in Gainesville and 20 in Jacksonville. Those efforts
will continue, with a focus on translational researchers
who can bridge basic science with clinical work.
Additional hiring will take place in medical oncology
and in subspecialties of cancer care, such as urology,
thoracic surgery and neurooncology, May said.
The recent arrival of Johannes Vieweg, M.D., has
been heralded as one example of the center's emphasis
on attracting top scientists and clinicians. Much of
Vieweg's research focuses on the development and
early clinical testing of new immunotherapies for
cancers of the genitourinary tract, including prostate
cancer. A new Good Manufacturing Practices facility
also is under construction; it will provide engineered
cells and small molecules required for vaccine-based
clinical trials and will produce new stem cell-based
therapies.
Meanwhile, the Cancer Center continues the search
to fill two key clinical leadership positions, a chief
medical oncologist with solid tumor expertise for the
Gainesville campus and a deputy director for the
cancer program in Jacksonville. Such individuals
happen to be in short supply.
"It's a problem that every university center faces,
and we're not unique to that," Wingard said. "For a
number of years, many of the trainees, when they
complete their fellowship, go into private practice.
What we are trying to do with our fellowship program
is to emphasize the pursuit of scholarly interests.
We're hoping to grow our own oncologists from our
own trainees."

X-RAY VISIONARIES
So where to go from here? Cancer Center administrators


UF' CANCER-
FIGHTING CAPABILITIES TOOK A
QUANTUM LEAP WITH THE OPENING OF
THE UF PROTON THERAPY IJNTITUTE IN
JACKSONVILLE LAST MOTH. THE f125
MILLION FACILITY, ONE OF ONLY FOUR LIKE IT IN
THE COUNTRY. WILL OFFER ONE MORE OPTION TO
CANCER PATIENTS THROUGHOUT THE
SOUTHEASTERN U.. PICTURED WITH ONE OF
THE THREE-STORY GANTRIES THAT POSITIONS
THE BEAM I$ INSTITUTE EXECUTIVE
DIRECTOR JTUART KLEIN.


say they will build on existing strengths, which include
a world-class bone marrow transplant program, the
surgical and radiation oncology programs and
significantly enhanced capabilities in epigenetics.
Robert Nuss, senior associate dean and associate
vice president for health affairs at the Health Science
Center-Jacksonville, said the center's structure as a
joint campus initiative also is a plus. And because of
Jacksonville's huge patient base, it will be a key
component in clinical trials development.
"I think the sum of the parts is greater than each
one alone, clearly," Nuss said. "I think that's the key
advantage of this opportunity, to allow us to be
successful utilizing the strengths of both campuses."
The development of a Health Science Center-wide
clinical trials office-a common resource for the
coordination of research studies and contract
negotiation-is another recent achievement, Wingard
said, and replaces the fragmented approach of the past.
In the past 12 months, 684 patients entered clinical
trials at UF. In contrast, in fiscal year 2002 only 337
subjects were enrolled in trials.
Challenges lie ahead. As the number of patients
grows, the outpatient clinics and the oncology staff
need to expand to accommodate them, he said. And
the availability of future research funding remains a
concern.
"The federal government has traditionally been the
major funding mechanism for cancer research, and
there are concerns with where those dollars will come
from in the future because of cutbacks," said Joe
Woelkers, the center's chief administrative officer.
"That, to me, is our biggest risk. I also know we're seeing
reimbursement for cancer care being reduced by


Medicare and other insurance carriers, and that's a
trend I think is going to continue. We're going to have to
find a way to be more economically efficient but continue
to provide the highest quality of care for our patients."
Cancer Center administrators also seek to become
one of 60 NCI-designated comprehensive cancer
centers, a quest complicated by current federal funding
constraints, said Joseph Simone, associate vice
president of health affairs for cancer programs. The
NCI grant would provide a few million dollars annually
for core facilities, recruitment and seed money for
research.
"More important than the money is that you are
now in an elite club, and it has an impact on your
ability to recruit people, it has an impact on your
standing in the university environment, and it has an
impact on your standing in the national cancer
community," Simone said.
Wingard likes to think back to a year ago, when
program leaders gave a presentation to the UFSCC
internal advisory board, articulating their vision, their
accomplishments, recruitment efforts and plans to
strengthen programs and collaborative research.
"For me that was an important turning point for the
Cancer Center," he said. "In the past, it seemed that
only a couple of individuals had a vision of what was to
be accomplished; it was then that I saw that the vision
was embraced by a wider circle of leaders who over
time will shape the future of the Cancer Center.
Buildings and money are important facilitators of
progress, but shared vision and broad leadership are
much more powerful agents of change. These changes
are now happening and are perhaps the most notable
accomplishments of the Cancer Center to date."


141 ; U ? Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.


THE END





ADMINISTRATION


Veteran



cancer


eader


joins UF



team


By Tom Fortner
A highly experienced leader
of some of the country's
best known academic
cancer centers has joined the
Health Science Center as associate
vice president of health affairs
for cancer program planning and
development.
Joe Simone, M.D., has a long and distinguished
career as a researcher, clinician and administrator,
most recently as the executive director of clinical
programs at the University of Utah's Huntsman
Cancer Institute. Before that he held leadership
positions at the Memorial Sloan-Kettering Cancer
Center in New York City and at St. Jude Children's
Research Hospital in Memphis, Tenn., where he
spent 25 years.
For the past five years, Simone has served as a
private consultant to academic centers and other
organizations whose activities touch on cancer
programs in some way. It was in his capacity as a
consultant that Simone was engaged by the HSC last
February to conduct a strategic assessment of cancer
programs operated by UF and Shands HealthCare.
In what is viewed as a time-limited appointment,
Simone has been asked by Senior Vice President for
Health Affairs Douglas J. Barrett, M.D. and Shands
HealthCare CEO Tim Goldfarb to work on two
important priorities. The first and most pressing is to
help plan the development of the new cancer hospital
under construction on the south side of Archer Road.
Simone said the initial phase of planning for the
facility in which all the most important decisions are
made is under way and will be his highest priority


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over the next few months.
The second priority is to help UF Shands Cancer
Center Director W. Stratford May Jr., M.D., Ph.D.,
and Deputy Director John Wingard, M.D., create a
blueprint for the growth of coordinated clinical
services in Gainesville and Jacksonville, with special
emphasis on the recruitment of a senior clinician to
serve as chief of hematology-oncology essentially
the quarterback of all cancer-related clinical services.
"Joe Simone's firsthand knowledge of what it takes
to build a top-ranked cancer program and his
extensive contacts in the field make him ideally
suited to help us at a critical time in the growth and
development of our programs," Barrett said.
That "critical time" in part describes the
confluence of several key developments: The Cancer
& Genetics Research Complex has just been
occupied, the UF Proton Therapy Institute in
Jacksonville has just come on line for patient care,
and the new cancer hospital must be configured in a


way that successfully accommodates not only cancer
services but also a trauma center and other
components of an acute care hospital.
Organizing these and other cancer-related
activities to best serve patients and their families is a
tall order, but one that Simone says must be achieved
if the Cancer Center is to earn National Cancer
Institute recognition and support as one of about 60
comprehensive cancer centers in the nation.
"Modern cancer care has become extremely
complex, and the relationship between the various
physicians and the various functions that a patient
faces has to be coordinated if you want the best
possible, efficient, high-quality way of doing things,"
said Simone, who earned his medical degree at
Loyola University of Chicago and did his clinical
training at Chicago-area hospitals in pediatric
hematology.
"I always put myself in the position of the patient,"
he said. "If I were a patient, what would I want?" Q


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. I U. 0 15






RESEARCH


By Christopher Hiatt


Oral decongestant replacement:

UF pharmacists challenge effectiveness


Leslie Hendeles (left) holds a drug
product that contains
pseudoephedrine while Randy
Hatton displays a similar-looking
drug product containing
phenylephrine, which the UF
pharmacists contend is ineffective at
the Food and Drug Administration's
approved dose.


University of Florida
pharmacists say a popular
decongestant in over-the-
counter medications is ineffective at
the Food and Drug Administration's
approved dose.
Phenylephrine is making its way
into oral cold and allergy medications
in response to new federal restrictions
on the sale of pseudoephedrine, an
industry standard decongestant that
can be used to illegally produce
methamphetamine.
As the late September deadline to
move medications containing
pseudoephedrine behind the counter
looms, many pharmaceutical
companies are reformulating some of
their common cold and allergy
medications to keep them readily
available on store shelves. Most
companies are switching to
phenylephrine, which cannot be used
to make methamphetamine.
But in a peer-reviewed letter to the
editor of the Journal ofAllergy and


Clinical Immunology, UF pharmacists
Leslie Hendeles, Pharm.D., and Randy
Hatton, Pharm.D., warn that
phenylephrine is poorly absorbed into
the bloodstream and will not work as
well as medications containing
pseudoephedrine. Hendeles, an FDA
consultant who served on the agency's
pulmonary advisory committee for six
years, said the FDA should further
investigate the drug as more companies
are beginning to use it.
"When it is ingested, it becomes
inactivated somewhere between the gut
and the liver," Hendeles said. "More
research needs to be done to determine
whether higher doses can be effective
and safe."
In 1976, the FDA deemed a 10
milligram oral dose of phenylephrine
safe and effective at relieving
congestion, making it possible for
companies to use the ingredient
without conducting studies.
But in their letter, Hendeles and
Hatton say phenylephrine does not


effectively relieve nasal stuffiness at
this dose. They say the FDA cited four
tests demonstrating efficacy at the 10
milligram dose, two of which were
unpublished and sponsored by drug
manufacturers. In contrast, the FDA
cited six tests demonstrating no
significant difference between
phenylephrine and placebo. Hendeles
said a higher dose may work, but no
research has been published regarding
safety at higher doses.
"They need to do a dose-response
study to determine at what higher dose
they get both efficacy and safety,"
Hendeles said.
Susan Johnson, Pharm. D., director
of the FDA's Division of
Nonprescription Regulation
Development, said once a drug's
ingredients are published in a final
monograph, pharmaceutical companies
can market it as directed without
further FDA approval.
The drug approval process is
designed to be public, she added, and


citizens have several opportunities to
raise questions about new drugs before
the agency approves them.
"This was all a public process,"
Johnson said. "If there are concerns, it
was not because the FDA turned a
deaf ear."
Under an amendment to the USA
Patriot Act, any medication containing
pseudoephedrine will be put under
lock and key nationwide by late
September. That means consumers will
no longer be able to purchase the
medicines off the retail shelf but will
have to ask store employees for the
drugs, show ID and sign a sales log.
Phenylephrine is not new to the
market. It has been commonly used in
nonprescription nasal sprays and in
eye and hemorrhoid medicines for
years. In these applications,
phenylephrine is highly effective. But
Paul Doering, M.S., a UF professor of
pharmacy who teaches about over-the-
counter medications, said that
phenylephrine has rarely been used in
oral decongestants, and for good
reason.
"As pharmacists we have always
avoided this drug," Doering said. "We
all know that it isn't absorbed into the
bloodstream well enough."
Sprays with phenylephrine are safe
and effective for the relief of nasal
stuffiness due to a simple cold lasting
less than a week, Hendeles said, but
the treatments should not be used for
stuffiness from allergies lasting longer
because a "rebound effect" can actually
worsen congestion.
"Consumers should go that extra step
and get it (pseudoephedrine) from
behind the counter," Hendeles said. O


161 w U* Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.





RESEARCH


Study pinpoints how genetic glitch could

keep some people from feeling full


By April Frawley Birdwell
Nearly 6 percent of morbidly obese children and adults have a genetic
defect that keeps them feeling like their stomach is running on empty, no
matter how much they have eaten.
Mutations of the melanocortin- 4 receptor, a gene found in brain cells that
play a role in regulating hunger, are the most common cause of genetic
obesity. Now University of Florida researchers have determined how some of


Zhimin Xiang, left, Carrie Haskell-Luevano, Sally Litherland, Bettina
Proneth and William Millard pinpointed how genetic mutations kept the
melaocortin-4 receptor from receiving signals that tell the body when it's
full and when it's hungry. The work puts scientists one step closer to finding
a way to correct these defects that can contribute to obesity.


these mutations cause the receptor to miss signals from molecules that tell
the body when to eat and when to put down the fork, placing scientists one
step closer to finding a way to correct these defects.
In a side-by-side comparison of 40 genetic mutations, UF medicinal
chemists found that 11 caused the receptor to behave abnormally, according
to findings recently published in the online edition of the journal
Biochemistry.
The goal is to discover the molecular glitch that causes the receptor to
malfunction so chemists can make drugs to treat it, said Carrie Haskell-
Luevano, Ph.D., an associate professor of medicinal chemistry in the
College of Pharmacy and the study's lead author. UF researchers have
already found a molecule that seems to correct one of the mutations, keeping
the hunger-signaling pathway running smoothly, Haskell-Luevano said.
"If you administer these compounds, it's a potential anti-obesity agent
because you feel full," Haskell-Luevano said. "On the other hand, if you
have cancer or wasting disease, if you administer an antagonist that blocks
or turns off the system, then you want to eat or you feel hungry.
"It directly controls the desire to eat."
About 30 percent of adults and 16 percent of children in the United States
are overweight, according to the Centers for Disease Control and Prevention.
Only a fraction of these people have genetic conditions or mutations that
are linked to obesity, but researchers say studying genetic obesity can also
help uncover clues to treating the nation's growing weight problem.
"There are so many factors that come into play," Haskell-Luevano said.
"It's a very simplistic approach to say what we study in a dish (completely
explains) why a person is obese. At the same time, taking it down to the
simplest level is how you identify specific problems." 0


Visit us online @ http://nev


New UF tool measures heart
implant patients' anxiety
Implantable heart devices are the treatment of choice for patients with
potentially life-threatening irregular heartbeats. But the thought of receiving
a high-energy shock to restore normal cardiac rhythm can strike fear in their
hearts nonetheless.
Now a new tool can help health-care providers identify which patients
who have received an implantable cardioverter defibrillator, or ICD, may
need psychological services to cope with anxiety. It's called the Florida
Shock Anxiety Scale, and UF researchers reported on its effectiveness in the
June issue of Pacing and Clinical Electrophysiology.
The study was done as part of a continuing series of cardiac psychology
investigations led by Samuel Sears, Ph.D., an associate professor in the
department of clinical and health psychology at the College of Public Health
and Health Professions, and Jamie Conti, M.D., an associate professor in
Sthe College of Medicine.
Patients with an ICD may be afraid that if the device fires they may harm
themselves or others, or create a scene. Or they may be fearful that certain
activities, such as exercise or sexual activity, might trigger a shock, said Emily
Kuhl, the study's lead author and a doctoral candidate in the department of
clinical and health psychology.
To test its effectiveness, researchers administered the Florida Shock Anxiety
Scale, a written questionnaire, to 72 ICD recipients. Researchers analyzed
participants' responses and determined that the scale evaluates the correct
underlying anxiety concepts and proved highly reliable.
"We also want to get the Florida Shock Anxiety Scale into the hands of
health-care providers so they use it, understand it and realize how important
it is," Kuhl said. Jill Pease






Health benefits of moderate
drinking extend to elderly
Older adults who consume a few alcoholic drinks a week are more likely to
ward off heart disease and live longer, a new multicenter study led by UF
researchers shows, but not for the reasons many might think. In a surprising
twist, alcohol's anti-inflammatory properties alone do not explain the reduced
risk of heart attack or death associated with light to moderate drinking, the
researchers report.
Published in the Archives of Internal Medicine, the current study suggests
the cardiovascular benefits of imbibing even one drink a week could instead
be tied to not yet fully understood cellular and molecular effects and genetic
interactions.
"Actually we expected to see that the protective effect of alcohol intake
was mediated by its anti-inflammatory properties, but we didn't find this, and
this is interesting," said Cinzia Maraldi, M.D., the study's lead author and
a lecturer in the College of Medicine's department of aging and geriatric
research. "Those other mechanisms that could explain that association
should be investigated."
UF Institute on Aging researchers, who collaborated with scientists from
several other academic institutions, studied 2,487 men and women between
the ages of 70 to 79 who had no history of heart disease. At the beginning
of the study, they gathered reports of alcohol consumption and measured
blood levels of two inflammatory markers, IL-6 and CRP.
Compared with the group of people who either never drank or were
occasional drinkers, the group of people who reported being moderate
drinkers consuming one to seven drinks a week were 26 percent less
likely to die and almost 30 percent less likely to experience a heart attack
or heart disease.
"This is very important because cardiovascular disease is among the
main causes of hospitalization and death in the United States and Europe,
so a 30 percent reduction may have important clinical and public health
implications," Maraldi said. -By Denise Trunk




Ts.health.utl.edu/ for the latest news and HSC events. *i j17


__ ____





RESEARCH










Healing p







in everyday

ByJohn Pastor


M cKnight Brain
Institute researchers

have shown ordinary

human brain cells may share

the prized qualities of self-re-

newal and adaptability normally

associated with stem cells.

Writing in Development, scientists described
how they used mature human brain cells taken
from epilepsy patients to generate new brain
tissue in mice.
Furthermore, they can coax these pedestrian
human cells to produce large amounts of new brain
cells in culture, with one cell theoretically able to
begin a cycle of cell division that does not stop
until the cells number about 10 to the 16th power.
"We can theoretically take a single brain cell
out of a human being and with just this one
cell generate enough brain cells to replace
every cell of the donor's brain and conceivably
those of 50 million other people," said Dennis
Steindler, Ph.D., executive director of the MBI.
"This is a completely new source of human brain
cells that can potentially be used to fight
Parkinson's disease, Alzheimer's disease, stroke
and a host of other brain disorders. It would
probably only take months to get enough
material for a human transplant operation."
The findings document for the first time the
ability of common human brain cells to morph
into different cell types, a previously unknown
characteristic, and are the result of the research
team's long-term investigations of adult human


UF McKnight Brain Institute researchers were able to purify and grow highly adaptable cells called adult human
neural progenitors from mature human brain tissue. The progenitor cells could be useful in the development of
therapies and diagnostics for brain disease. The green marker indicates a support brain cell called an astrocyte
and the red marker is an indication of a stem cell, which is highly valued for its ability to transform into any cell
type. Blue marks the cell nucleus. Photo by Noah Walton/UF McKnight Brain Institute.


stem cells and rodent embryonic stem cells.
Last year, the researchers published details
about how they used stem-like brain cells from
rodents to duplicate neurogenesis the process of
generating new brain cells in a dish. The latest
findings go further, showing common human
brain cells can generate different cell types in
cell cultures. In addition, when researchers
transplanted these human cells into mice, the
cells effectively incorporated in a variety of brain
regions.
The human cells were acquired from patients
who had undergone surgical treatment for
epilepsy and were extracted from support tissue
within the gray matter, which is not known for
harboring stem cells.
When the donor cells were subjected to a bath
of growth agents within cell cultures, a type of
cell emerged that behaves like something called a
neural progenitor a cell that is a bit further
along in development than a stem cell but shares
a stem cell's vaunted ability to divide and
transform into different types of brain cells.


Even when the cells from the epilepsy patients
were transplanted into mice, bypassing any
growth enhancements, they were able to take
cues from their surroundings and produce new
neurons.
"It was a long and difficult process, but we
were able to induce what are basically support
cells in the human brain to form beautiful new
neurons in a dish," said Noah Walton, a graduate
student in the neuroscience department at the
UF College of Medicine. "But what we really
needed is for these support cells to turn into
neurons in the brain, and we found we could get
them to do it. Something in the environment in
the rodent brain is sufficient to get these cells to
become neurons."
Scientists speculate a small amount of existing
progenitors may be emerging from the gray
matter of the brain and multiplying in torrents,
or perhaps the aging clock of the mature cells
actually turns backward when the donor cells are
in a new environment, returning them to past
lives as progenitors or as stem cells. O


181 ; Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.





LIBRARY


Dr. May Edward Chinn examines a young patient in New York City in this
1930 photo. Dr. Chinn graduated from medical school in 1926 and
practiced medicine in Harlem for 50 years.



SCHEDULE OF SEPTEMBER EVENTS


UF Health Science Center Libraries host "Changing

the Face of Medicine" traveling exhibition


By Ned Davis
Women doctors are the focus of a new traveling exhibition that opened Aug. 30 at
the UF Health Science Center Libraries.
"Changing the Face of Medicine: Celebrating America's Women
Physicians" tells the extraordinary story of how American women who wanted to practice
medicine have struggled over the past two centuries to gain access to medical education
and to work in the medical specialty of their choosing.
The exhibit focuses on women physicians, including UF's Rebecca Rainer Pauly, M.D.,
associate chair for medical student education in the department of medicine. Pauly, one
of only two women from Florida included in the exhibit, spoke at the opening reception
Aug. 30 at the library.
Since the mid-1800s, when Elizabeth Blackwell became the first woman in America to
earn an M.D., women have made enormous strides in every branch of medicine and have
achieved success in work once considered unsuitable for them. They are educators,
surgeons, family practitioners, specialists, government officials and researchers on the
cutting edge of new medical discoveries.
"Women have brought fresh perspectives to the medical profession," said Donald A.B.
Lindberg, M.D., director of the National Library of Medicine. "They have turned the
spotlight on issues that had previously received little attention, such as the social and
economic costs of illnesses and the low numbers of women and minorities entering
medical school and practice."
Two interactive kiosks traveling as part of the exhibition offer access to the National
Library of Medicine's "Local Legends" Web site (www.nlm.nih.gov/locallegends), which
features outstanding women physicians from every state, and the exhibition's own Web
site at http://www.nlm.nih.gov/changingthefaceofmedicine.
"We are delighted to have been selected as a site for this exhibition," said Faith A.
Meakin, director of the UF Health Science Center Libraries. "Although 'Changing the
Face of Medicine' focuses on women in medicine, its lessons about persistence,
dedication and courage in one's life choices speak to everyone men and women and
young adults and to people in all lines of work."
The National Library of Medicine and the American Library Association organized
the exhibition with support from the NLM, the National Institutes of Health Office of
Research on Women's Health and the American Medical Women's Association.
The UF Health Science Center Libraries are sponsoring free programs and other events
for the public in connection with the exhibition, as part of its 50th anniversary celebrations.
Call Ned Davis at 352-392-2362 or e-mail ned@library.health.ufl.edu for more information,
or visit the library's Web site at www.library.health.ufl.edu to preregister. Q


Sept. 8: Keynote speech
Regina Morantz-Sanchez, Ph.D., a professor of
history at the University of Michigan, speaks on
"Gynecological Surgery and Public Controversy: Dr.
Mary Dixon-Jones on trial, 1892" at 3 p.m. in the MSB
Auditorium, followed by a light reception at the library.

Sept. 12: Whatever Happened to the
Women's Health Movement?
Part 1: Lecture "The Influence of the Women's Health
Movement on Healthcare Today."
Byllye Avery, M.Ed., founder of the National Black
Women's Health Project and recipient of a
MacArthur Foundation "genius" grant, and Betsy
Randall David, R.N., Ph.D., Center for Creative
Education, will both speak, offering historical and


sociopolitical perspectives on women's influence on
health care at noon in Communicore Room Cl-11.
Lunch will be provided.

Part 2: Panel discussion -"Whatever Happened to the
Women's Health Movement?"
Mary Ann Burg, L.C.S.W., Ph.D., director of UF's
Women's Health Research Center, will moderate a
panel discussion from 3 p.m. to 4:30 p.m. at the
Reitz Union, Room 361. Speakers will be drawn
from the original founders of the Gainesville
Women's Health Center, including Byllye Avery,
Betsy Randall David, Randi Cameon, Marilyn
Mesh and others. A reception will follow.

Sept. 19: Women and the Health Center
Nina Stoyan-Rosenzweig, historian and HSC


archivist, at noon in Communicore Room C1-15.
Lunch will be provided.

Sept. 20: Health-care career fair
The HSC Libraries and the UF Center for
Precollegiate Education & Training will host a
health-care career fair for students from Gainesville
high schools. It runs from 9 a.m. to 3 p.m. at
locations around the HSC and the library.


Sept. 26: African-American Women in
Medicine
Donna Parker, M.D., UF College of Medicine assistant
dean for minority cultural affairs and a clinical
assistant professor of pediatrics, will speak at noon in
Communicore Room C1-15. Lunch will be provided.


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. U 1 0 19





JACKSONVILLE


h roughout her career Ann

Harwood-Nuss, M.D., has

had many goals, but one

stands out: She wants to make a

difference.
Serving as UF's director of graduate medical
education for the Health Science Center-Jacksonville
since 1992 and as assistant and then associate dean
for educational affairs for HSC-Jacksonville from
1994 until she semiretired June 30 has given
Harwood-Nuss that opportunity... and then some.
But she traces her drive to make a difference back to
her days growing up in a big, close-knit family in
northern Iowa, long before she assumed those roles.
"My father was a physician, and my mother was a
very intelligent woman who with my father managed
to raise seven Harwood kids," she said.
Harwood-Nuss followed in her father's footsteps


Ann Harwood-Nuss

Making a difference one goal at a time


By Patricia Bates McGhee


and graduated from the University of Iowa College of
Medicine.
During her residency at Michigan State, the
emerging field of emergency medicine caught her
interest. Harwood-Nuss left Michigan to become the
emergency medicine program director at the
University of Chicago and from there was recruited
as an associate professor at UF and chair for the
department of emergency medicine at University
Hospital Jacksonville (now Shands Jacksonville).
During this time she also published the first edition
of "The Clinical Practice of Emergency Medicine," a
textbook that to this day makes a difference.
"When Dr. Harwood-Nuss started her textbooks
in 1991, there were only a couple in existence in this
specialty," said David Vukich, M.D., chair of the
department of emergency medicine in Jacksonville.
"Because of her national reputation she was able to
attract an incredible list of contributors, and what
followed was the bible of emergency medicine a
tool that many emergency physicians keep on hand
and refer to often during clinical shifts."
Turning her focus to graduate medical education
was a natural transition for Harwood-Nuss and yet
another environment where she could make a
difference, though not without effort.
"The challenges are certainly there," she said,


"and meeting them has required hard work, much
collaboration with my colleagues and the support of
the great and visionary leaders of the College of
Medicine Drs. Barrett, Tisher, Watson, Nuss and
others."
Also challenging are the many changes in graduate
medical education, Harwood-Nuss said.
"Graduate medical education has become highly
regulated, and the daily challenges of meeting the
requirements have been stimulating, gratifying and,
on occasion, frustrating," she said.
Meeting these challenges and changes head on -
and with aplomb sets Harwood-Nuss apart, said
Robert Watson, M.D., senior associate dean for
educational affairs.
"Ann Harwood-Nuss is the person most
responsible for success of our educational programs
in Jacksonville," he said. "She has been an exemplary
Designated Institutional Officer for our GME
programs, someone who quietly, intensely and with
complete commitment to our local GME mission
produces perfection.
"She is among the most organized and dependable
people with whom I have ever worked, and it was
always nice knowing that whatever task she was
doing would be done better than I could do it, thus
without worry on my part," said Watson, who at this


year's medical education banquet presented her with
the prestigious Society of Teaching Scholars
Lifetime Achievement Award (pictured above). "Ann
is one of those who can't be replaced, just succeeded."
When asked what she liked best about her job in
educational affairs, Harwood-Nuss offered many
examples. "It allowed me the opportunity to work
with dedicated, intelligent physicians, residents and
staff and stimulated me to find solutions to problems,
to overcome barriers to the conducting of our
educational mission and, on occasion, to have the
chance to be innovative and bring new ideas or
solutions to our Jacksonville campus," she said. "But
I think the best part of the job is that it placed me in
a position to make a difference," she said.
As of July 1, Harwood-Nuss continues to work in
the Dean's Office half time.
The rest of her time will be spent on her hobbies,
which range from traveling with her family and
reading last year she read every Pulitzer Prize
winner of the last 15 years to enjoying her cats,
Thelma and Louise.
"I especially love to watch my husband (associate
vice president for health affairs and College of
Medicine senior associate dean Robert Nuss, M.D.)
work hard in our garden, where he really does make a
difference," she said. O


201 U1 Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events.





ADMINISTRATION


Dr. Peter Stacpoole, who's heading up UF's pursuit of a major translational science grant, visits with Dr. Jennifer Miller and her
young patient, who is involved in a clinical study in the General Clinical Research Center.


U F By Tom Fortner


FUgears up for new world order of clinical research


he U.S. clinical research enterprise has long been considered the most
productive of any country's in the world. And yet there are well-
documented flaws: Lines of inquiry are too tightly focused within single
disciplines. Although there are many basic science discoveries, the translation of
these findings into treatments and cures takes too long and yields too little.
There are disconnects between academic researchers, drug and device
manufacturers, and the financing that nurtures new discoveries. A young
investigator has few incentives to pursue a career in academic clinical research.
Ready or not, help may be on the way. As part of its Roadmap initiative to
reengineer the U.S. biomedical research enterprise, the National Institutes of
Health has created a new grants-in-aid program designed to address these long-
standing deficits. It's called the Clinical and Translational Science Award, or
CTSA, and it's just one of the Roadmap initiatives that has academic medical
centers scrambling to adapt.
The person charged with the gargantuan task of getting UF ready for the
CTSA is Peter Stacpoole, Ph.D., M.D., associate dean for clinical research and
training in the College of Medicine. He's the logical choice for the job, since he
heads the UF program the CTSA is designed not so much to replace as to
gradually engulf- the General Clinical Research Center.
The GCRC and 77 centers like it represent a pillar of NIH-sponsored, patient-
oriented research and training in the United States. Operated "in the framework
of a human laboratory" from a combined 10-bed inpatient unit and outpatient
facility on the third floor of Shands at UF, the GCRC has enjoyed continuous
funding since 1962, and it appears to be aging well: At its last competitive
renewal in December, UF's GCRC received one of the top scores in the country,
an "outstanding" rating and another five years of funding at approximately $5
million per year.
But that, as they say, is yesterday's news. During the next five years, Stacpoole
said, the expectation is that the 78 GCRCs at 68 academic health centers will
transition to just 60 institutional holders of a CTSA, a prospect that is creating


anxiety at UF and elsewhere.
"My own view," said Stacpoole, "is that this is going to be a winnowing down
process in which the'haves' will continue to remain competitive for new initiatives
and will be looked on as the national leaders in research and training, and those
who do not succeed in getting a CTSA will evolve primarily into more of a non-
research, primary training mode. And the middle class of academic health centers
is probably going to go away," in terms of their participation in federally supported
clinical research.
Faced with what he describes as this "new world order," Stacpoole's first task
- with the help of a cast of dozens of other UF faculty and administrators was
to develop a proposal for a planning grant that would lay the groundwork for a
full CTSA application to be submitted in early January 2007. The planning
grant, submitted to NIH last March, outlines UF's vision for creating the
university's central academic home for clinical and translational research and
training.
This plan would create a sweeping new matrix organization that spans 11 UF
colleges, Shands and VA teaching hospitals and, through IFAS, has a presence
in all 67 Florida counties. Under the supervision of UF Vice President for
Research Win Phillips, the new Center for Clinical and Translational Research
will have a broadly representative steering committee and three subcommittees
dealing with research projects, training and career development, and information
technology. With several million dollars in annual funding to support
investigator-initiated translational research and training, the center will wield
considerable influence on campus and even offer an advanced degree in clinical
and translational research.
Stacpoole believes UF with its history of being interdisciplinary, experience
in running clinical trials, substantial existing and planned infrastructure, and
a GCRC with a successful track record will be competitive for a CTSA award.
"Every place will have its own pearls," he said. "I think we have a lot of
potential to be innovative." Q


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. IU U. 0 21






DISTINCTIONS


COLLEGE OF DENTISTRY

LINDA BARTOSHUK,
Ph.D., an internationally
known researcher in the
chemical senses of taste and
smell, has been appointed
a presidential endowed
professor of community
dentistry and behavioral
sciences in the College of Bartoshuk
Dentistry. Bartoshuk, who
first joined the UF faculty as a visiting professor
in the College of Public Health and Health
Professions last year, comes to UF from Yale
University. She is a fellow of the National
Academy of Sciences and the only female NAS
member at UF.
Bartoshuk's research, which explores the
genetic variations in taste perception and how
taste perception affects overall health, will
complement care provided through the UF
McKnight Brain Institute's Center for Taste
and Smell, housed in the College of Dentistry.
Bartoshuk was the first to discover that burning
mouth syndrome, a condition predominantly
experienced by postmenopausal women, is
caused by damage to the taste buds at the
front of the tongue and is not a psychosomatic
condition, as many believed. Center experts
treat patients suffering from smell and taste
disorders or loss of taste due to disease or
cancer therapy.

SAMUEL LOW, D.D.S.,
M.S., M.Ed., associate
dean for faculty practice
and continuing education,
has been elected secretary-
treasurer of the American
Academy of Periodontology.
As secretary-treasurer, Low
will become president of the
organization in 2010.
Low has a distinguished record of executive
leadership in organized dentistry, and is a past
president of the Florida Dental Association and
a member of the American Dental Association
House of Delegates.

COLLEGE OF MEDICINE JACKSONVILLE

MICHAEL GAYLE, M.D.,
an associate professor of
pediatrics, recently passed
the American Board of
Pediatrics recertification
examination in pediatric
critical care medicine.
PCCM recertification is
part of ABP's Program for Gayl
Maintenance of Certification
in Pediatrics -or PMCP -designed to provide
assurance that ABP-certified pediatricians and
subspecialists are up-to-date with their specialty.

MICHAEL SUK, M.D., J.D., an assistant
professor of orthopaedic surgery in the College
of Medicine-Jacksonville, received the American
Medical Association Foundation's 2006
Leadership Award, presented in association with
the Pfizer Medical Humanities Initiative.


The honor, extended
to 55 individuals from
across the nation,
recognizes outstanding
nonclinical leadership
skills in advocacy,
community service
or education. It also
provides medical Suk
students, residents and
fellows, young physicians and international
medical graduate physicians leadership
development training to further strengthen
their efforts toward advancing health care in
America.

GEORGE WILSON,
M.D., associate chair
and an associate
professor of community
health and family
medicine at the College
of Medicine Jacksonville,
has been appointed to
a two-year term on the
American Academy of
Family Physicians' Commission on Finance and
Insurance.
AAFP, representing more than 94,000
physicians and medical students nationwide,
is the largest medical specialty organization
devoted solely to primary care.

COLLEGE OF MEDICINE


SAEED R. KHAN,
Ph.D., a professor in
the department of
pathology, was recently
named to the National
Institutes of Health
Center for Scientific
Review's Urologic and
Kidney Development
and Genitourinary
Diseases Study Section.


Khan


Members of NIH study sections play a key
role in reviewing and recommending NIH
grant applications for approval. Study section
members also pay close attention to the
development of research in their own scientific
fields.
Khan will serve as a member of the study
section until 2010.

WENDY B. LONDON,
Ph.D., a research
associate professor
in the department of
epidemiology and
health policy research,
was honored with the

Audrey Evans Prize for
the Outstanding Paper London
in Clinical Research
at the Advances in Neuroblastoma Research
meeting in May. London, who also serves as
principal investigator and associate program
director of the Children's Oncology Group
Statistics and Data Center at UF, received the
honor for her efforts to determine the best
statistical way to assess the risk for disease


recurrence, progression or death in children
with neuroblastoma. London is chairwoman of
the International Neuroblastoma Risk Group
Project's statistics committee and performs
research to define new universal guidelines for
assessing risk.

COLLEGE OF NURSING

JUDY CAMPBELL, M.S.N.,
A.R.N.P., a doctoral
student, has been chosen
to receive a scholarship
supporting the work of
future leaders in geriatric
nursing. Campbell is one
of 18 recipients nationwide
to receive the "Building Campbell
Academic Geriatric
Nursing Capacity" predoctoral scholarship,
funded by the John A. Hartford Foundation
and administered by the American Academy
of Nursing. The scholarship, which provides
$40,000 a year for two years, will enable
Campbell to concentrate on her research
full time. Campbell's research examines
interventions that can possibly delay placement
of those with dementia in long-term care. The
multimillion-dollar Building Academic Geriatric
Nursing Capacity Scholars Award Program was
launched in 2000 to produce gerontological
leaders in the areas of research, academics and
practice who will ultimately improve elderly care.

PUBLIC HEALTH AND HEALTH PROFESSIONS

NEHA DIXIT, a graduate
student in the department
of clinical and health
psychology, received a
predoctoral fellowship
from the American Heart
Association's Florida/
Puerto Rico Affiliate
Research Committee to
Dixit
support her dissertation
work in cardiac psychology and cognition.

JOE DZIERZEWSKI, a
graduate student in the
department of clinical and
health psychology, received
the Retirement Research
Foundation Master's
Thesis Proposal Research
Award from the American
Psychological Association's
Adult Development and Dzierzewski
Aging division.

SAMUEL SEARS, Ph.D.,
an associate professor in
the department of clinical
and health psychology,
has been named to the
advisory council of the
Sudden Cardiac Arrest
Foundation. The new
nonprofit organization's
mission is to increase
sudden cardiac arrest survival rates through
education and awareness.


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DISTINCTIONS


COLLEGE OF VETERINARY MEDICINE

SARAH JUDD, a junior
veterinary student at the
University of Florida, has won
the Hill's Big Win Scholarship
Challenge, sponsored by
Hill's Pet Nutrition Inc. Judd
will receive a scholarship
for one year's tuition, worth
approximately $25,000. The Judd
announcement was made
in June at the American College of Veterinary
Internal Medicine's annual meeting in Louisville.
Students from veterinary schools throughout the
United States who participated in the Scholarship
Challenge took a short-answer quiz and winners
had their school name posted on a Hill's Web site.
Fellow students could then go online and cast their
vote for their school. UF received the most votes,
which resulted in Judd winning the scholarship.


College of Nursing dean named
: ll to advisory council on nurse and
physician shortages

College of Nursing Dean Kathleen Ann Long is among
a select group of national health-care leaders named to
the newly created Council on Physician and Nurse Supply,
which will address the growing problem of nurse and
physician shortages. Council members will monitor data
and act as advocates for change, advising legislators and
others on ways the supply of nurses and physicians can be
altered to meet the public's needs.
Council co-chairs are Richard "Buz" Cooper, M.D.,
Long and UF nursing alumna Linda Aiken, Ph.D., R.N., both
professors at the University of Pennsylvania. The council is
based in the University of Pennsylvania's Consortium for Health Workforce Research and Policy,
a joint program of the schools of Nursing and Medicine and the Leonard Davis Institute of Health
Economics.
The council's goals are to bring objectivity to the study of physician and nurse supply and to
shape public policy. Council members will examine a range of domestic and international issues
that must be addressed as the United States attempts to better align its health-care workforce with
its future health-care needs. It is the only multidisciplinary organization in the nation dedicated
exclusively to addressing issues of nurse and physician supply.
Council members represent universities across the country as well as major hospitals and
health-care organizations. Tracy Brown Wright


GRANTS


Researcher works to remove barriers to breast cancer


screening for women with physical disabilities


ByJill Pease


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women with disabilities and 30
health-care providers to learn their
perspective on cancer screening
facilitators and barriers.


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and it will set the stage for women in
the community to be involved in the
research as partners, not just
participants," Lopez said. O


Visit us online @ http://news.health.ufl.edu/ for the latest news and HSC events. I U. 0 23







SI l 1 .. I,. H ,1 J .i F'i 1 11 1 1 I I .,,J,- I


Ill.I


As part of a two-week geriatrics clerkship small group program, HSC medical student
Miriam Ricardo works with a patient the Malcom Randall Veterans Affairs Medical
Center.


Donald Tucker, hospital care technician, has worked for three years
discharging animals at the large animal hospital.


Published by
UF Health Science Center
Office of News & Communications
Senior Vice President,
Health Affairs
Douglas J. Barrett, M.D.
Director, News &
Communications
Tom Fortner


Editor
Denise Trunk
Senior Editors
Melanie Fridl Ross, John Pastor
Designer
Mickey Cuthbertson
Writers
April Frawley Birdwell, Tracy Brown,
Sarah Carey, Christopher Hiatt,


Linda Homewood, Lindy McCollum-
Brounley, Patricia McGhee, John
Pastor, Jill Pease, Melanie Fridl Ross,
Denise Trunk

Photojournalist
Sarah Kiewel
Support Staff
Cassandra Jackson, Beth Powers,
Kim Smith,

The POST is the monthly internal
newsletter for the University of
Florida Health Science Center, the
most comprehensive academic
health center in the Southeast,
with campuses in Gainesville
and Jacksonville and affiliations
throughout Florida. Articles feature
news of interest for and about HSC
faculty, staff and students. Content


may be reprinted with appropriate
credit. Ideas for stories are welcome.
The deadline for submitting items to
be considered for each month's issue
is the 15th of the previous month.
Submit to the editor at dtrunk@ufl.
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UNIVERSITY

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