Group Title: Animal Science Department mimeograph report - University of Florida Agricultural Experiment Station ; AN65-2
Title: Antibiotics and copper in pig starter rations
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Permanent Link: http://ufdc.ufl.edu/UF00072955/00001
 Material Information
Title: Antibiotics and copper in pig starter rations
Series Title: Animal Science Department mimeograph report
Physical Description: 4 p. : ; 28 cm.
Language: English
Creator: Combs, G. E ( George Ernest ), 1927-
Wallace, H. D ( Harold Dean )
Berry, Thomas Hart, 1934-
University of Florida -- Agricultural Experiment Station
Publisher: Florida Agricultural Experiment Station
Place of Publication: Gainesville Fla
Publication Date: 1964
 Subjects
Subject: Swine -- Feeding and feeds -- Florida   ( lcsh )
Antibiotics in animal nutrition -- Florida   ( lcsh )
Copper in animal nutrition   ( lcsh )
Genre: government publication (state, provincial, terriorial, dependent)   ( marcgt )
non-fiction   ( marcgt )
 Notes
Statement of Responsibility: G.E. Combs, H.D. Wallace and T.H. Berry.
General Note: Caption title.
General Note: "July, 1964."
 Record Information
Bibliographic ID: UF00072955
Volume ID: VID00001
Source Institution: University of Florida
Rights Management: All rights reserved by the source institution and holding location.
Resource Identifier: oclc - 77537972

Full Text



Animal Science Department
Mimeograph Report AN65-2


Florida Agricultural
Experiment Station
Gainesville, Florida
July, 1964


ANTIBIOTICS AND COPPER IN PIG STARTER RATIONS

G. E. Combs, H. D. Wallace and T. H. Berry J/


The benefits derived from supplementing swine rations with antibiotics have
been recognized for many years. More recently copper sulfate, when properly
administered, has proven to be an effective growth promotant. The efficacy of
compounds of this type is always of interest to the nutritionist as well as the
producer.

The purpose of this study was to compare the growth-promoting ability and
indirectly the ability to reduce the incidence of scours of several antibiotics
with copper sulfate.

Experimental

Seventy-five pigs weaned at two weeks of age were allotted on the basis of
weight and litter into fifteen lots of five pigs each. All lots were self-fed
ad libitum in concrete floor pens for 42 days.

The experimental treatments were as follows:


Treatment I -
Treatment 2 -

Treatment 3 -

Treatment 4 -

Treatment 5 -


Basal
Basal + 250 gm. Aureo. S-P-250 per ton
(aureomycin sulfamethazine penicillin)
Basal + 250 gm. Tylan per ton
(tylosin phosphate)
Basal + 250 gm Taomyxin per ton
(terramycin oleandomycin)
Basal + 250 p.p.m. copper
(CuSO4'5H20)


The composition of the basal ration is presented in table I.


Results

The performance of each replication as well as the average of the three
replications is summarized in table 2. The response as measured by gain and
feed consumed to either antibiotic or copper sulfate supplementation was con-
sistent throughout the three replications. A somewhat less consistent response


I/ Combs, Associate Animal Nutritionist; Wallace, Animal Nutritionist and Berry,
Research Assistant, Florida Agricultural Experiment Station. The assistance
of W. E. Collins and L. S. Taylor is gratefully acknowledged. This study was par-
tially supported by funds from American Cyanamid Co., Chas. Pfizer and Co., Inc.
and Eli Lilly and Co.







-2-


was obtained in feed required per unit of gain, with this criterion only the pigs
receiving copper sulfate were more efficient than the basal fed groups.

The efficacy of the treatments was definitely in favor of the groups that
were fed either Aureo S-P-250 or copper sulfate. In all replications pigs in
these two groups gained more rapidly than-pigs fed either Tylan or Taomyxin.
The feed efficiency data indicate that all antibiotic supplemented groups re-
quired about the same amount of feed per pound of gain, whereas the copper-fed
pigs were considerably more efficient than any other treatment group. The over-
all response to Tylan:and Taomyxin indicated that the growth promoting ability
of these antibiotics was approximately equal.

Although the rate and efficiency of gain figures as well as initial cost
indicate that copper sulfate would be the feed additive of choice in this ex-
periment, caution should be exercised:When using this compound. Adequate and
thorough mixing is mandatory to prevent the occurrence of deaths from copper
toxicity.

Summary

Seventy-five early .weaned pigs were used to compare the relative effectiveness
of Aureo S-P-250, Tylan, Taomyxin.and copper sulfate in promoting increased rate
and efficiency of gain.

All supplemented groups gained faster than the non-supplemented basal group.
Only copper sulfate was effective in reducing the feed required per pound of gain.
Pigs fed either Aureo S-P-250 or copper sulfate gained at approximately the same
rate and both gained faster than pigs fed Tylan or Taomyxin. The performance of
pigs fed either Tylan or Taomyxin was similar.







-3-


TABLE I. COMPOSITION OF BASAL RATION


Ingredients Lb.

Ground yellow corn 56.40
Soybean meal 25.70
Cane sugar 10.00
Fat, stabilized 3.00
Defluorinated phosphate 2.00
Salt .50
Trace minerals .10
Vitamin supplement ./ .20
Vitamin BI2 supplement 2/ .10
Vitamin A and D premix _/ 2.00
100.00


J/ Contained 2,000 mg. riboflavin; 4,000 mg. pantothenic acid,
and 10,000 mg. choline chloride per pound.


9.000 mg. niacin


2/ Contained 12 mg. vitamin B12 per pound.


3/ Contained 14 gm. vitamin (10,000 I.U./gm.), 2 gm. vitamin D
and 892 gm. yellow corn.


(9,000 l.U./gm.)


GEC:gem
7/16/64
1000 copies








-4-


TABLE 2.


RESPONSE OF EARLY WEANED PIGS TO
VARIOUS ANTIBIOTICS AND COPPER SULFATE


Treatment Basal Aureo. Tylan Taomyxin Copper
S-P- Sulfate
250


Replication I

No. pigs
Av. init. wt.,
Av. Final wt.,
Av. daily gain,
Av. daily feed,
Feed/gain, lb.

Replication 2

No. pigs
Av. init. wt.,
Av. final wt.,
Av. daily gain,
Av. daily feed,
Feed/gain, Ib.

Replication 3


lb.
lb.
lb.
lb.


lb.
Ib.
Ib.
Ib.


No. pigs
Av. init. wt., Ib.
Av. final wt., lb.
Av. daily gain, lb.
Av. daily feed, Ib.
Feed/gain, Ib.


5
9.2
38.7
.70
1.33
1.90


5
9.5
37.7
.67
1.14
1.70


5
9.4
35.0
.61
1.13
1.85


5
9.1
48.6
.94
1.61
1.71


5
9.5
48.3
.92
I .73
1.88


5
9.3
53.2
1.05
1.92
1.83


5
9.2
44.0
.84
1.44
1.71


5
9.5
41.8
.77
1.46
1.90


5
9.3
39.4
.71
1.24
1.75


5
9.2
43.4
.81
1.42
1.75


5
9.6
44.0
.82
1.54
1.88


5
9.4
42.9
.80
1.39
1.74


5/
9.2
49.1
.95
1.53
1.61


5
9.5
48.8
.94
I.58
1.68


5
9.4
45.8
.87
1.29
1.48


Av. replication I. 2 & 3


Av. init. wt.,
Av. final wt.,
Av. daily gain,
Av. daily feed,
Feed/gain, lb.


Ib.
lb.
lb.
Ib.


9.4
37.1
.66
I.20
I.82


9.3
50.0
.97
1.75
1.81


9.3
41.7
.77
1.38
1.79


9.4
43.4
.81
1.45
1.79


9.4
47.9
.92
1.47
1.59


J./ Two pigs died, gross
copper toxicity.


post-mortem examination did not indicate death due to




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