Group Title: Animal husbandry and nutrition mimeograph series - Florida Agricultural Experiment Station ; no. 60-9
Title: Thyroprotein and cortisone in starter rations for early weaned pigs
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Permanent Link: http://ufdc.ufl.edu/UF00072893/00001
 Material Information
Title: Thyroprotein and cortisone in starter rations for early weaned pigs
Series Title: Animal husbandry and nutrition mimeograph series
Physical Description: 4 p. : ; 28 cm.
Language: English
Creator: Combs, G. E ( George Ernest ), 1927-
Vandepopuliere, Joseph Marcel, 1929-
Wallace, H. D ( Harold Dean )
University of Florida -- Agricultural Experiment Station
Publisher: Florida Agricultural Experiment Station
Place of Publication: Gainesville Fla
Publication Date: 1959
 Subjects
Subject: Swine -- Feeding and feeds -- Florida   ( lcsh )
Swine -- Growth -- Florida   ( lcsh )
Genre: government publication (state, provincial, terriorial, dependent)   ( marcgt )
non-fiction   ( marcgt )
 Notes
Statement of Responsibility: by G.E. Combs, J.M. Vandepopuliere and H.D. Wallace.
General Note: Caption title.
General Note: "December, 1959."
Funding: Animal husbandry & nutrition mimeograph series ;
 Record Information
Bibliographic ID: UF00072893
Volume ID: VID00001
Source Institution: University of Florida
Rights Management: All rights reserved by the source institution and holding location.
Resource Identifier: oclc - 76971530

Full Text

Animal Husbandry and Nutrition Florida Agricultural
Mimeograph Series No. 60- 9 Experiment Station
December, 1959 Gainesville, Florida
THYROPROTEIN AND CORTISONE IN STARTER-
RATIONS FOR EARLY WEANED PIGS /.
by

G. E. Combs, J. M. Vandepopullere and H. D. Wallace 2/

Previous work at the Florida Station has demonstrated the inability of a
fortified corn-soybean meal ration to support maximum growth.with early weaned
pigs. Since this type ration has proven adequate for growing finishing swine
a series of studies was initiated in an attempt to improve thelperformance of
young pigs when fed a fortified corn-soybean meal ration.

In the present study Protamone, aniodinated protein, and cortisone, a
hormone that has among its physiological properties the.ability to increase
blood glucose level, were added to starter and grower rations.
Experimental

One hundred forty pigs weaned at two weeks of age were used in two experi-
ments. The pigs were allotted at random from out come groups on the basis of
weight and general condition, The treatment groups~ er fed ad fibitum from
self feeders and were housed in sheltered concrete-floored pens. The compo-
sition of the basal ration is presented in table i,

Experiment J

Lot I Basal ration
Lot 2 -Basal ration + 20 mg. Protamone/Ib. feed
Lot 3 !-Basal + 20 mg. Protamone t .25 mg. cortisone/lb. feed
Lot 4 Basal 4 20 mg. Protamone + .50 mg. cortisone/lb. feed
Lot 5 Basal + 20 mg. Protamone + 1.00 mg. cortisone/lb. feed

Experiment 2

Lot I Basal ration
Lot 2 Basal ration + 20 mg. Protamone/Ib feed
Lot 3 Basal ration + 20 mg. Protamone + .10 mg. cortisone/lb.
Lot 4 Basal ration + 20 mg. Protamone + .05 mg. cortisone/lb feed


1/ Cortisone acetate supplied by Merck and Co., inc. ,.Protamone (lodinated
casein) contained 1-thyroxine and was supplied by Agri-Tech, Inc.

_/ Combs, Vandepopulleree and Wallace, Assistpnt Professor, Research Assistant
and Associate Professor respectively, Department of Animal Husbandry and
Nutrition. The assistance of W. E. Collins and L. S. Taylor, Swine Herds-
men, is gratefully acknowledged.






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Table I. Composition of


Basal Ration I/


Ingredient

Ground yellow corn

Soybean meal

Sugar

Rolled Oats

Lard

Ground limestone

Steamed bone meal

Salt

Trace minerals 2

Vitamin antibiotic
premix /


J [ IIU I


i/ During the 5th and 6th week this ration was modified by replacing the
sugar, rolled oats and lard with ground yellow corn.

2/ Supplied the following in the ration (ppm):

manganese (35.5), iron (43.8), copper (3.0),
cobalt (1.0), zinc (50.0), and potassium (4.7).

. / Premix supplied the following per pound of ration:

Vitamin A, 2000 I.U.; vitamin D, 400 I.U.;
niacin, 20 mg.; riboflavin, 3 mg.;
pantothenic acid, 10. mg.; choline 500 mg.;
thbimine, 3 mg.; folic acid, 3 mg; pyridoxine,
I mg.; vitamin 812, 20 mcg.; chlortetracycline,
25 mg.; pencillin, 6 mg.; and streptomycin 9 mg.


I I --


Pounds

45.30

32.00

10.00

5.00

3.00

.80

1.30

.50

.10


2.00

100.00






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Results and Discussion

A summary of the results obtained from both experiments is presented in
Table 2.

Experiment 1. During the starter period (4 week period) the pigs re-
ceiving Protamone and Protamone plus .50 and I mg. cortisone gained slower .
and were less efficient in converting feed to gain than the basal fed pigs.
The pigs fed rations containing Protamone plus .25 mg. cortisone gained
slightly faster and more efficiently than the pigs on any of the other treat-
ments. A simi lar situation was found when performance on the starter and-
grower rations was combined (6 week period).

Since a decrease in performance was observed with increasing levels of
cortisone Experiment 2 was conducted to study rate and efficiency of gain
with lower levels of cortisone.

Experiment 2. As was observed in Experiment I during the starter period
Protamone failed to stimulate growth and only a slight increase over the
basal group was obtained by the addition of cortisone. When performance on
both the starter and grower rations (6 week period) was considered it was
evident that rate of gain for all treatments is essentially the same; the
pigs fed the basal ration required considerably less feed per pound gain
than the pigs on the other treatments.

A comparison of the combined performance of the basal and Protamone -
fed pigs on Experiments I and 2 showed that Protamone decreased gains'
approximately 5 percent and increased the feed required per pound of gain
about 7 percent.

Summary

Pigs weaned at 2 weeks of age were fed fortified corn soybean starter
and grower rations supplemented with Protamone or a Protamone cortisone
mixture.

Daily gains and feed efficiency were slightly decreased by the
addition of 20 mg. of Protamone per pound of ration. Performance "on the"
Protamone cortisone mixtures varied with the level of cortisone, with
the lower levels being the most effective. However the response at any
level was small and insignificant.






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Table 2. Results of Supplementing Starter and Grower Rations With
Protamone and a Protamone Cortisone Combination


Experiment I

Basal Protamone Protamone Protamone Protamone
Treatment + + +
.25 m9 Cor- .50mg. Cort- I mg. Ort-
Ssone isone isone

Number pigs 15 15 1 5 5 15
Av. Init. wt.,lbs. 10.3 10.3 10.3 10.2 10.3
Av. final wt., Ibs. 33.2 32.2 35.7 33.5 31.7

4 week period

Av. daily gain, lbs. .36 .35 .40 .34 .27
Av. dal!y feed, lbs. .82 .83 .88 .82 .72
Lb. feed/lb gaih, lbs. 2.28 2.37 2.20 2.41 2.67

6 week period

Av. daily gain, lbs. .55 .52 .60 .55. .51
Av. daily feed, lbs. 1.21 1.21 1.31 1.24 1.13
Lb. feed/lb gain, Ibs. 2.20 2.33 2.18 2.25 2.21


Experiment 2

Protamone Protamone Protamone
Treatment Basal t +
,10 m cortisone .05 ma. cortisone


Number pigs
Av. init. wt., lbs.
Av. final wt. Ibs.

4 week period

Av. daily gain, Ibs.
Av. daily feed, Ibs.
Lb. fee/ilb gain, Ibs.

6 week period

Av. daily gain, Ibs.
Av. daily feed, lbs.
> Lb. feed/lb gain Ibs.


10
9.3
41.6


.46
.83
1.80


.77
1.32
1.71


10
9.4
41.0


.46
.89
1.93


.75
1.41
1.88


10
9.3
43.2


10
9.3
40.1


.49
.96
1.96


.48
.89
1.85


.80
1.60
2.00


.73
1.48
2.03


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'. I




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