| Material Information
||Various forms of penicillin as antibiotic supplements for growing-fattening swine
||Animal husbandry mimeograph series
||4 leaves : ; 28 cm.
||Wallace, H. D ( Harold Dean )
Gillespie, Larry, 1925-
Haines, C. E
University of Florida -- Dept. of Animal Husbandry and Nutrition
||University of Florida, Dept. of Animal Husbandry and Nutrition
||Place of Publication:
||Swine -- Growth -- Florida ( lcsh )
Swine -- Health -- Florida ( lcsh )
||government publication (state, provincial, terriorial, dependent) ( marcgt )
bibliography ( marcgt )
non-fiction ( marcgt )
||Includes bibliographical references (leaf 4).
||Statement of Responsibility:
||H.D. Wallace, L. Gillespie and C.E. Haines.
| Record Information
||University of Florida
||All rights reserved by the source institution and holding location.
||oclc - 76941616
Animal Husbandry Mimeograph October, 1955
Series No. 55-9
VARIOUS FORMS OF PENICILLIN AS
ANTIBIOTIC SUPPLEMENTS FOR GROWING-FATTENING SWINE1
H. D. Wallace, L. Gillespie and C. E. Haines2
Procaine penicillin has been used effectively in the rations of growing-
fattening swine at several experiment stations (1). However, in studies at
the Florida Station the antibiotic has always failed to improve growth rate.
This may be explained by differences in the bacterial populations encountered.
Also, it has been suggested that the stability of procaine penicillin may not
be adequate for the warm yearly climate encountered here. However, this last
point does not seem too logical since our feeds have been mixed regularly and
not held for periods of more than two weeks.
This experiment was undertaken to determine if other forms of penicillin
would effectively stimulate the growth rate of growing-fattening swine fed
Forty weanling Duroc pigs were divided into five experimental lots of
eight each according to weight, sex, litter and previous treatment. The pigs
were self fed in concrete pens which were cleaned and washed daily. The
basal ration is presented in Table 1.
1This study was supported in part by a grant-in-aid from Eli Lilly and Co.,
2Wallace, Associate Animal Husbandmin, Gillespie and Haines, Graduate Assist-
ants, Department of Animal Husbandry and Nutrition. The technical assistance
of W. E. Collins, Swine Herdsman, is gratefully acknowledged.
Table 1. BASAL RATION1
Ground yellow corn 79.00
Soybean oilmeal 19.00
Ground limestone 1.00
Steamed bonemeal .50
Trace mineralized salt2 .53
1. Vitamin fortifications included 2,000 I.U.
of vitamin A per lb. of feed, and 20 mg.
B12, 4 gm. riboflavin, 8 gm. pantothenic
acid, 18 gm. niacin and 20 gm. choline
chloride per ton of feed.
2. The trace mineralized salt was composed of:
iodized salt (50 lb,) MnS04O H20 (921 gm.),
FeS04 H20 (398 gim.), CuS04 o (125 gm.),
coco3 (10 gm.) and ZnSo4 Hg2 (350 gm.)
The experiment was started on May 14, 1955 and was terminated after eight
The experimental treatments and a summary of the results are given in
Table 2. All forms of penicillin were added at a rate of 2.5 mg. per lb. of
Results and Discussion
There were no significant differences between growth rate of the control
pigs (Lot 1) and those that received the various forms of the antibiotic.
Daily feed consumption was similar for all lots except Lot 4 which received
the dipenicillin V. Pigs in this lot ate about one quarter of a pound of feed
less per day per head. However, they gained well and the lower feed intake
was reflected in better feed conversion for this lot of pigs. Feed conversion
was quite good for all lots of pigs and with the exception of Lot 4 was not
affected greatly by the addition of penicillin.
Table 2. Summary of Results
Lot Number 1 2 3 4 5
Experimental Basal Ration Basal ration Basal ration Basal ration
Variation Basal Ration / procaine / penicillin V / dipenicillin V / potassium
penicillin (crystalline penicillin V
Number of pigs
Av. initial wt. Ibs.
Av. final wt. lbs.
Av. daily gain, Ibs.
SAv. daily feed
Feed required per
lb. gain, Ibs.
Days on test
Penicillin V has been developed
for oral usage.
by Eli Lilly and Compaay in an attempt to produce an acid stable penid.clin
2 One pig removed from experiment after L wks. because of unthriftinesse
This experiment tends to confirm previous results at this Station on the
use of penicillin for swine. Either the organism population is not covered
by the bacterial spectrum of this antibiotic or it was not fed at the optimum
level. However, 2.5 mg. of penicillin per pound of feed has elicited significant
growth responses at other stations.
1. Braude, R., H. D. Wallace and T. J. Cunha. 1953. The Value of Antibiotics
in the Nutrition of Swine: A Review. Antibiotics and Chemotherapy. 3:
100 cc -4.