Group Title: Mimeo report - University of Florida Everglades Experiment Station ; 59- 17
Title: Diethylstilbestrol, hydroxyzine, tapazole and tri-fluomeprazine in steer fattening programs
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Permanent Link: http://ufdc.ufl.edu/UF00067555/00001
 Material Information
Title: Diethylstilbestrol, hydroxyzine, tapazole and tri-fluomeprazine in steer fattening programs
Series Title: Everglades Station Mimeo Report
Physical Description: 7 leaves : ; 29 cm.
Language: English
Creator: Chapman, H. L ( Herbert L. ), 1923-
Haines, C. E
Crockett, J. R ( Joe Richard ), 1926-
Everglades Experiment Station
Publisher: Everglades Experiment Station
Place of Publication: Belle Glade Fla
Publication Date: 1959
 Subjects
Subject: Beef cattle -- Feeding and feeds -- Florida   ( lcsh )
Feed additives   ( lcsh )
Genre: non-fiction   ( marcgt )
 Notes
Statement of Responsibility: H.L. Cjapman, Jr., C.E. Haines, and J.R. Crockett.
General Note: "April, 1959."
General Note: Caption title.
 Record Information
Bibliographic ID: UF00067555
Volume ID: VID00001
Source Institution: University of Florida
Rights Management: All rights reserved by the source institution and holding location.
Resource Identifier: oclc - 65288594

Full Text



Everglades Station Mimeo Report 59-17


Diethylstilbestrol, hydroxyzine implants, tapazole and tr '
fluomeprazine in steer fattening programs

H. L., Chapman, Jr., C. E. Haines, and J. CrockeA

New compounds continue to be produced which appear to have value y
improving the performance of cattle being fattened in feed lot. During tvw
recent experiments at the Everglades Station several of these were investi-
gated. The purpose of the experiments herein reported was to determine the
value of oral and implanted diethylstilbestrol, hydroxyzine implants, tapa-
zole and trifluomeprazine for steers being fattened on pasture and in dry-
lot.
Experiment 819-2

One hundred and twenty two-year old steers were divided into 15 lots
of eight animals each and fed for a 131 day period to study the interrela-
tion of hydrozyzine implants with stilbestrol administered, orally and by
implant, to steers fattened on pasture and in drylot; and to determine the
effect that level of concentrate feed intake had on this interrelationship.
Groups receiving oral stilbestrol were given 10 milligrams daily, in the
concentrate mixture:' those implanted, 24 milligrams a&,''te beginning of the
experiment. One half of the animals in each lot received 60 milligrams
of bydioxyzine, implanted at the beginning of the experiment. Limited fed
animal received 6 pounds of a concentrate feed daily, which was comprised
of'2 parts ground snapped corn, 2 parts citrus pulp and one part cottonseed
meal. 'Tull fed groups received the same feed, except urea replaced the pro-
tein equivalent of 25 percent of the cottonseed meal. Pasture fed groups
grazed R6selawn'St. Augustinegrass. Animals in drylot received Roselawn
St. Augustinegrass silage as their roughage.
Experiment 819-6

One iHubdred and four two-year-old steers were divided into 13 lots of
Cightfanimals eiac and fed for a 112 day period to study the value of tapa-
zdle and'the tranquiliier trifluomeprazine for cattle being fattened on
pasture and in drylot and to see if the effect of these two compounds would
be iltered"by implanted stilbestrol or level of concentrate feed intake.
Tapazole was administered orally during the last 63 days of the experiment
at the'rate of 600 milligrams per animal per day and trifluomeprazine was
administered oially during the entire feeding period at the rate of 5 milli-
grams pdr animal daily. One half of the animals in each lot received 24
milligrams of stilbestrol implanted at the beginning of the experiment. Con-
oeitrate feed was fed the same as in experiment 819-2. Pasture fed groups
grazed Roseldwn St. Augustinegrass. Hegari (regular) sorghum silage was
fed as roughage to the steers fed in drylot.

Acknowledgments

These studied were supported in part by grant-ln-aids from Smith,
Kline sad .French raboratdrfes. Philadelphia,'and Chas. Pfizer and Co., Inc.,
Terre Haute, Indidna. Tapazole and Stilbosol was furnished by Ell Lilly
and Company, "Indianapolis. Stilbestrol and hydroxyzine implants were fur-
nished by Chas. Pfizer and Co,', Inc. Trifluomeprazine was furnished by
Smith. Kline and French Laboratories, Philadelphia.








Orally vs. Implanted Diethylstilbestrol Summary


Experimental
Tre-atment


Av.
Initial
Wt.
(1ho \


Av.
Final
Wt.
(1bs)


Av.
Total
Gain
(bs)


Av.
Daily
Gain
(flhfm


Av.
Intran-
sit
Shrink
(C)


Av.
Dressing
Percent
(IM


Av.
Cooler
Shrink
(I)


Av.1/
Final
Carcass
Value
(0)


Av.2/
Initial
Steer
Ccst
($)


Av. feejcost/
steer '
Pasture
or
Grain Silage
($) ($)


Av. return::
above feed I
and steer
costs (W)


Pasture


No feed
Limited feed
Full feed
No feed 4 24 mg. implant
Limited 4 24 mg. implant
Full 4 24 mg. implant
Full 4 36 mg. implant
Limited + 10 mg. orally
Full 4 10 mg. orally


Dry Lot


Limited feed
Full feed
Limited + 24 mg. implant
Full 4 24 mg. implant
Limited 4 mg. orally
Full 4 10 mg. orally


I/ Carcass price on grade and


yield basis: Choice 48.50;


Good 43.80; Standard 43.00; Utility


42.25; Cutter -
40.50.


2/ Initial steer prices, live basis: Standard 22.50; Utility 21.00; cutter 18.CO


3/ Feed Costs:
(a) Full fed concentrate, Cwt @ 2.62
(b) Limited fed concentrate, Cwt. @ 2.64


(c) Silage, ton @ 5.00
(d) Pasture fertilization, acre @ 9.00


759
741
741
754
789
771
747
763
756


807
870
1018
814
947
1073
1084
948
1071


48
129
277
60
158
302
337
185
315


0.37
0.99
2.12
0.46
1.21
2.30
2.57
1.41
2.40


4.1
4.2
4.0
3.0
3.0
3.6
3.6
3.7
3.9


52.1
56.6
63.4
52.8
54.9
62.7
62.9
56.8
64.5


4.2
3.4
2.9
3.8
3.4
2.8
2.9
3.5
2.8


159.69
194.43
258.47
164.75
206.18
276.77
276.75
213.70
277.95


159.39
155.61
155.61
158.34
165.69
161.91
156.87
160.23
158.76


20.57
70.87

20.57
77.42
79.39
20.57
79.78


S4,50
4.5o
4.50
4.50
4.50
4.50
4.50
4.50
-4.50


734
744
746
754
768
750


-4.20
13.75
27.49
1.91
15.42
32.94
35.99
28.40
34.91


910
1057
934
1161
988
1104


176
313
188
407
220
354


1.34
2.39
1.44
3.11
1.68
2.70


4.6
4.8
5.7
4.7
4.6
4.8


56.6
63.2
56.9
62.4
56.6
61.0


3.7
3.0
3.1
2.9
3.3
2.9


201.70
271.78
206.60
294.42
223.51
274.10


154.14
156.24
156.66
158.34
172.80
157.50


20 .57
78.34
20.57
78.34
20.57
72.44


"15.59
5.76
-16.64
6.55
19.50
5.90


11.40
31.44
12.73
51.19
10.62
38.26


___


(lb r, ( s ,, ,


_ __~__


Experiment 819-2.


k












Experiment 819-2 Suimary of Hydroxyzine vs. No Hydroxyzine im-
plants for steers receiving a full intake of
concentrate feed.


Hydroxyzine


No
Hydroxyzine


initial weight (Ibs).
final weight (lbs)
total gain (Ibs)
daily gain (lbs)

intransit shrink (%)
dressing percent (C)
cooler shrink (U)


Average final-carcass value (~) I/
Average initial steer value ($) /
Average feed cost per steer ($) 3/
Coiicntrate feed
Grass silage
Pasture
Average return above steer and feed


275.24
157.08

77.03
2.62
2.57
costs ($) 35.94


1/ Carcais price on grade and-yield basis: Choice 48.50;
Standard 43.00; Utility 42.25; Cutter 40.50.


Good 43.80:


2/ Initial steer prices, live basis: Standard 22.50; Utility -
S21.00; Cutter 18.00.

3/ Feed costs:

(a) ull fed concentrate, cwt @ 2.62
(b) Limited fed concentrate, cwt @ 2.64
(c) Silage, ton @ 5.00
(d) Pasture fertilization, acre @ 9.00


Average
Average
Average
Average

Average
Average
Average


748
1098
350
e.67

5.0
63.0
2.7


755
1065
310
2.36

3.3
62.8
3.0


270.56
158.55

77.03
2.62
2.57
29.79


I- -


- ---------- --- -- --~----- --~-












Experiment 819-2 -


Summary of Hydroxyzine vs. No Hydroxyzine im-
plants f6r steers receiving a full intake of
concentrate feed, plus stilbestrol.


No
----------------------------N--~-
Hydroxyzine Hydroxyzine

Average initial weight (Ibs) 752 760
Average findl weight (Ibs) 1124 1073
Average toStal gain (Ibs) 372 313
Average daily gain (ibs) 2.84 2.39

Average intransit shrink (5) 5.0 3.1
Average dressing percent (6) 62.7 62.7
Average cooler shrink (;) 2.7 3.1

Average final'carcass value 1/ ($) 280.75 273.05
Average initial steer value / ($) 157.92 159.60
Average feed cost/steer 3/ ()
Coiientrate feed 77.68 77.68
Grass silage 2.49 2.49
SPasture* .2.70 2.70
Average Yeturn above steer dnd feed costs ($) 39.96 30.58
1/ Carcass price on-grade and yield basis: Choice 48.50; Good -
" 43.80: Standard 43.00; Utility 42.25; Cutter 40.50.

2/ Initial steer prices, live basis: Standard 22.50; Utility -
21.00; Cutter 18.00.

3/ Feed costs:


Full fed concentrate, cwt. @ --
Limited fed concentrate. cwt. @-
Silage, ton 0.
Pasture fertilization, acre @ -


2.62
2.64
5.00
9.00








Experiment 819-6. Summary of Effect of Tapazole and Trifluomeprazine

Av. Av.1/ Av.2/ Av. re-
Av. Av. Av. Av. Intran- Av. Av. Final Initial Pasture turn above
Initial Final Total Daily sit Dressing Cooler Carcass Steer or feed and .
Experimental Wt. Wt. Gain Gain Shrink Percent Shrink Value Cost Grain Silage steer coasEts
Treatment (bis) (Ibs) (ibs) (ibs) (%) (_) () (4) ($) (M) ($) (i)

Pasture

No feed 631 749 118 1.05 6.9 53.0 1.9 156.11 132.51 4.50 19.10
Limited feed 626 812 186 1.66 4.2 56.5 1.6 183.87 131.46 17.70 4.50 30.21
Full feed 629 956 327 2.92 3.9 60.1 1.4 236.17 132.09 70.34 4.50 29.24
Limited feed 4
trifluomeprazine 622 834 212 1.89 4.3 56.3 1.3 188.68 130.62 17.70 4.50 35.86
Full feed 4
trifluomeprazine 631 939 308 2.75 3.3 60.1 1.4 233.37 132.51 66.19 4.50 30.17
Limited feed $ Tatazole 628 811 183 1.63 3.8 56.1 1.5 187.03 131.88 17.70 4.50 32.95
Full feed 4 Tapazole 632 908 276 2.46 1.9 58.9 1.5 220.50 132.72 55.66 5.14 26.98

Dry Lot

Limited feed 613 709 96 0.86 3.1 53.1 1.5 150.45 128.73 17.70 9.07 -5.05
Full feed 613 932 319 2.85 3.0 60.2 1.5 232.93 128.73 73.81 2.69 27.70
Limited feed 4
triflucmrprazine 618 716 98 0.88 4.6 52.5 1.3 147.96 129.78 17.70 10.75 -10.27
Full feed 4
t-rifluomeprazine 606 901 295 2.63 3.3 59.0 1.6 219.74 127.26 68.32 3.36 20.80
Limited feed 4 Tapazole 608 716 108 0.96 2.9 53.1 1.6 155.57 127.68 17.70 8.51 1.68
Full feed 4 Tapazole 619 916 297 2.65 3.2 59.0 1.3 223.73 129.99 60.48 3.58 26.68

1/ Carcass price on grade and yield basis: Choice 48.50; Good 43.80; Standard 43.00; Utility 42.25; Cutter 40.50

2/ Initial steer prices, live basis: Standard 22.50; Utility 21.00; Cutter 18.00


3/ Feed Costs: (a) Full fed concentrate, Cwt @ 2.62
(b) Limited fed concentrate, Cwt. @ 2.64


(c) Silage, ton @ 5.00
(d) Pasture fertilization, acre @ 9.00









Summary of Stilbestrol vs. No Stilbestrol


Stilbestrol


No
Stilbestrol


Average initial weight
Average total weight
Average t6tal gain
Average daily gain

Average intransit shrink
Average dressing percent
Average cooler shrink

Average final"value of carcass 1/
Average initial steer value 2/"'
Average total feed cost/steer 3/
Concentrate
Sbrghum silage
"Pasture
Return above feed and steer cost


I/ Caricads price on grade and yield basis: Choice 48.50:
Standard 43.00; Utility 42.25; Cutter 40.50.


Good- 43.80;


2/ Initial-steer prices, live basis: Standard 22.50; Utility 21.00;
Cutter 18.00.

3/ Fee'a Costs:
(a) nill fed concentrate, Cwt. @ 2.62
(b) Limited fed concentrate, Cwi. @- 2.64
(c) Silage, ton @ 5,00
(d) Pasture fertilization, acre @ 9.00


(Ibs)
(lbs

(Ibs)

()

(0)

($)
($)

($)

($)


622
865
243
2.17

3.6
57.0
1.6

200.42
130.62

38.64
2.87
2.48
25.81


621
813
192
1.71

3.9
56.7
1.4

186.88
130.41

38.64
2.87
2.48
12.48


_ _I ~___


Experiment 819-6.









Summary of Results




1. Didthylstilbestrol either rally (10 mg/animal/day) or im-
planted (24 mg) increased average daily gains of steers
in dryldt.
2. There was no significant difference in average daily gain
attributable to method of administration of stilbestrol.
3. Response to stilbestrol by steers being fattened on pasture
was variable.
4. Stilbestrol i:adttadignifi~nly ef6feij'naraasit shrink;
48hour codoeihihrink. 6ressing-pefce*t, 6r'. carcas -
grade;-
5. Implants of the tranquilizer Hydroxyzine (60 mg/animal)
stimulated average daily gains by 13 percent in steers on full
feed and 19 percent for steers receiving a full feed of con-
centrate plus stilbestrol.
6. Hydr6xyzine implants did not stimulate average daily gains
for steers receiving no or limited concentrate feed intake.
7. Response in growth stimulus to the tranquilizer Trifluo-
meprazine (5 mg./animal/day) was variable.
8. Tapazole (600 mg./animal/day, during last 63 days of feed-
ing period) did not increase average daily gains at either
level of concentrate feed intake, on pasture or in drylot.
9. Average net returns, above steer, feed and fertilizer costs,
were greater in most cases on pasture than in drylot.




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