CREATING AND SETTING OF THE CTSI -- OUR EXPERIENCE AND SUCCESSFUL EXAMPLES

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Title:
CREATING AND SETTING OF THE CTSI -- OUR EXPERIENCE AND SUCCESSFUL EXAMPLES
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Conlon, Michael
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University of Florida
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Mumbai, India
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Collected for University of Florida's Institutional Repository by the UFIR Self-Submittal tool. Submitted by Michael Conlon.
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CREATING AND SETTING OF THE CTSI -OUR EXPERIENCE AND SUCCESSFUL EXAMPLES

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THE NATIONAL INSTITUTES OF HEALTH CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAM In 2006, NIH developed the Clinical and Translational Science Award (CTSA) Program The CTSA consortium vision: to improve human health by transforming the research and training environment to enhance the efficacy and quality of clinical and translational research The 62 CTSA institutions are linked together to transform the local, regional, and national environment to increase the efficiency and speed of clinical and translational research

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THE FOUR TRANSLATIONS

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THE EXAMPLE OF TOBACCO Basic science 1912 Clinical science in the 1930s Policy 1960s current Public awareness, legislation Tobacco use is the single greatest cause of preventable death globally

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IMPROVE RESEARCH 1. Services to Investigators 2. Training those involved in research 3. Transforming the research environment

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SERVICES TO INVESTIGATORS

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BASIC SCIENCE Core lab services -genotyping, behavioral, IPS cells, simulation center, biorepository, mass spectroscopy, NMR, global metabolomics, human imaging Collaborations with other university core laboratories, laboratory cores in cancer, genetics, aging, brain, emerging pathogens Workshops and consulting in Good Laboratory Practice

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CLINICAL SCIENCE Twelve clinical research venues including Clinical Research Center, Veterans Affairs, Tuberculosis Study design, data collection, data analysis, informatics, recruitment and retention Human subject protection, budget development assistance, Investigational New Drug applications

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POPULATION SCIENCE Health Impacts practice based research network (PBRN) with Florida State University Integrated data repository Collaborations with High Performance Computing, Informatics institute National Dental practice based research network Team based approach Mentoring, implementation studio

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TRAINING THE RESEARCH WORKFORCE Junior medical faculty -didactic, experiential and mentoring programs Doctoral students Research Coordinators Research nurses School teachers

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ACADEMY OF RESEARCH EXCELLENCE

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TEAM SCIENCE

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COLLABORATIO N ACROSS THE UNIVERSITY Agriculture Design, Construction and Planning Dentistry Medicine Journalism Nursing Veterinary Medicine Business Engineering Liberal Arts and Sciences Education Fine Arts Public Health and Health and Health Professions Law Health and Human Performance Pharmacy

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COLLABORATION ACROSS THE STATE AND NATION UF Health and College of Medicine Jacksonville Florida State Orlando Miami CTSI 61 additional CTSAs across the country including Duke, Harvard, Northwestern, Mayo Clinic, Wisconsin, UCSF

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TRANSFORMING RESEARCH

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SOUTHEAST CENTER FOR INTEGRATED METABOLOMICS (SECIM)

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INTEGRATED DATA REPOSITORY

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PERSONALIZED MEDICINE

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IMPACT OF THE CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

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The social network of research at the University of Florida 2013 Points represent faculty. (n=6,044) Points are connected if faculty have written a grant or a paper together. Blue points represent CTSI investigators (n=950). CTSI investigators occupy the central positions in the main component. Figure by Chris McCarty and Raffaelle Vacca, Bureau of Business and Economic Research

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ECONOMIC IMPACT, 2008 2012 $1 : $11 8,351 $1.1B CTSI operating expenditures External funding Person years of employment in Florida Economic activity in Florida On average, every $1 of CTSI operating expenditures helped spur an additional $11 in external funding Source: UF Bureau of Economic and Business Research assessed regional economic impact of CTSI operations from 2008 2012

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RESEARCH IMPACT From 2009 2012, affiliation as a CTSI investigator is associated with: increase in external funding increase in patent filings increase in publications in top 100 journals Source: UF Bureau of Economic and Business Research compared records of CTSI investigators before and after association with CTSI, controlling for annual shocks to productivity of all UF researchers and shifts in average productivity of each academic unit.

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THANK YOU! University of Florida Clinical and Translational Research Building Home of the Clinical and Translational Science Institute, Institute on Aging, Department of Health Outcomes and Policy, Department of Aging and Geriatric Research, Department of Epidemiology and Department of Biostatistics. For more information please contact us at www.ctsi.ufl.edu ; info@ctsi.ufl.edu ;352 273 8700