Citation
Effects of Aerobic Exercise on Structural Changes in Brain Areas Associated with Pain Processing in Older Adults

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Title:
Effects of Aerobic Exercise on Structural Changes in Brain Areas Associated with Pain Processing in Older Adults
Creator:
Quach, Helena Lynn
Publication Date:
Language:
English

Notes

Abstract:
Brain structures such as the prefrontal cortex, insula and cingulate gyrus are known to be activated during pain processing. Furthermore, loss of brain structures, including cortical thinning, are seen in chronic pain patients, but also occur with normal aging. Interestingly, older adults also are at increased risk for developing chronic pain. Studies of cognition in older adults with dementia have shown recovery of brain structure along with improvements in cognition following moderate exercise programs. This study tested whether an aerobic exercise program would increase brain structures associated with pain processing in older adults. Four healthy older adults completed a 12-week aerobic exercise program using stationary bicycles. Structural MRI was performed before and after the exercise program. A total of 8 cortical and subcortical areas were targeted and included areas associated with pain processing and modulation (Insular, Rostral Anterior Cingulate, Caudal Anterior Cingulate, and Lateral Orbital Frontal) and others which are not associated with pain processing (Superior Temporal, Middle Temporal, Inferior Temporal, and Isthmus Cingulate). Significant post-exercise differences were found for right side Insular (p = .009), Rostral Anterior Cingulate (p = .036), Lateral Orbital Frontal (p < .001) and the Caudal Anterior Cingulate (p = .029) within the left hemisphere only. ( en )
General Note:
Awarded Bachelor of Health Science, summa cum laude, on May 8, 2018. Major: Health Science. Emphasis/Concentration: General Health Sciences
General Note:
College or School: College of Public Health & Health Professions
General Note:
Advisor: Joseph Riley. Advisor Department or School: Public Health and Health Professions

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Source Institution:
University of Florida
Holding Location:
University of Florida
Rights Management:
Copyright Helena Lynn Quach. Permission granted to the University of Florida to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.

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UF Undergraduate Honors Theses

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