Preliminary tests on N-substituted p-nitrobenzamides as insecticides

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Material Information

Title:
Preliminary tests on N-substituted p-nitrobenzamides as insecticides
Physical Description:
10 p. : ; 27 cm.
Language:
English
Creator:
Bottger, G. T
Yerington, Albert P., 1914-
Gertler, S. I
United States -- Bureau of Entomology and Plant Quarantine
Publisher:
U.S. Department of Agriculture, Agricultural Research Administration, Bureau of Entomology and Plant Quarantine
Place of Publication:
Washington, D.C
Publication Date:

Subjects

Subjects / Keywords:
Insecticides -- Testing   ( lcsh )
Organic compounds -- Synthesis   ( lcsh )
Genre:
federal government publication   ( marcgt )
non-fiction   ( marcgt )

Notes

General Note:
Caption title.
General Note:
"E-764."
General Note:
"December 1948."
Statement of Responsibility:
by G.T. Bottger and A.P. Yerington and S.I. Gertler.

Record Information

Source Institution:
University of Florida
Rights Management:
All applicable rights reserved by the source institution and holding location.
Resource Identifier:
aleph - 030294086
oclc - 780166898
System ID:
AA00025176:00001

Full Text
1 ;. .F .*,,

December 1948 E-764


United States Department of Agriculture
Agricultural Research Administration
Bureau of Entomology and Plant Quarantine



PHBLIMINARY TESTS ON N-SUBSTITUTED p-NITBDBEIZAMIDES AS IIUSLCTICIDES

By G. T. Bottger and A. P. Yerington, Division
of Control Investigations, and S. I. Gertler,
Division of Insecticide Investigations


Twenty-three N-substituted Z-nitrobenzamides, which were prepared
by reacting Z-nitrobenzoyl chloride with amines under suitable condi-
tions, have been tested in the insecticide-testing laboratory of this
Bureau at Anaheim, Calif. All the compounds have the nitro group in
the para position. They contain in common the

0

02N C group.


These compounds were tested as 25-percent dusts against five or more
species of leaf-feeding insects. On the basis of the results of these
tests# some of the more toxic materials were tested further at reduced
concentrations.

For comparative purposes, tests were made with DDT, pure gamma
isomer of benzene hexachloride, and parathion, the insecticidal effec-
tiveness of which against the various species tested was already known.

The insects and mites used in the tests were as follows:

Alder flea beetle (Altica ambiens (Lec.))
Armyworm (Cirphis unipuncta (Haw.))
Celery leaf tier (lyctaenia rubigalis (Guen.))
Large milkweed bug (Oncopel us fasciatus Dall.)
Pea aphid (Macrosiphum ii (Kltb.))
Two-spotted spider mite (Tetranychus bimaculatus Har-ey)
Variegated cutworm (Peridroma margaritosa (Ha5.-Y)

The armyworm, the celery leaf tier, the large milkweed bug, and
the variegated cutworm were reared in the laboratory, whereas all the
other species were collected from field populations.

In the tests with coleopterous and lepidopterous insects, sections
of leaves were dusted in a settling chamber and then placed in petri
dishes with the test insects. The two-spotted spider mites and the pea
aphids were dusted while in contact with their hosts. The rilk_7eed c'"s






2 -

were dusted while confined in crystallizing dishes, to which untreated food
was afterward added. A minimum of 24 coleopterous or lepidopterous insects
were employed in each test. However, many more than 24 mites and aphids
were used in most of the tests.

The results of the tests with the known insecticides against the various
test species are presented in table 1. High kills were obtained with all the
cjcpcfnds at concentrations of 0.5 percent or less against all the species
tested, except the alder flea beetle, which was killed with a 3-percent dust.

Data on the 23 compounds tested as 25-percent dusts are presented in
table 2. No apparent injury resulted from any of the compounds when these
dusts were applied to green foliage of alder, castor-bean, collard, Windsor
bean, and Swiss chard. The materials showing mortalities of 65 percent or
higher against one or more species were N-amyl-k-nitrobenzamide; N-butyl-2-
nitrobenzamide; N-oec-butyl-2-nitrobenzamide; N N-diethyl-j&-nitrobenzamide;
N ,N-dii sobutyl-o-nitrobenzamide; N,N-dii sopropyl- -nitrobenzamide; M ,N-di-
methyl-j-nitrobenzamide; N,N-dipropyl-j-nitrobenzamide; and N-isopropyl-2-
niltrobenzamide.

Five of these compounds, all of which were toxic to the two-spotted
spider mite, were again tested against this mite at concentrations of 5 and
1 percent. The results of these tests are shown in table 3. At the 5-per-
cent level mortalities ranged from 64 percent with N,N-dipropyl-i-nitroben-
zamide to 92 percent with N,N-diethyl-2-nitrobenzamide. However, at 1 per-
cent no appreciable mortality resulted.

Of all the compounds tested N,N-diisopropyl-.-nitrobenzamide appeared to
be the most toxic to the greatest number of species.

Because of the high kills from concentrations of 0.5 percent or less of
the standard insecticides against most of the test insects, it does not appear
likely that any of the N-substituted 2-nitrobenzamides could compete success-
fully with these standard insecticides and/or the many other insecticides
alrRady established in the industry.












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